PMC:7205724 / 25278-25897 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"896","span":{"begin":565,"end":569},"obj":"Gene"},{"id":"897","span":{"begin":571,"end":575},"obj":"Gene"},{"id":"898","span":{"begin":577,"end":581},"obj":"Gene"},{"id":"899","span":{"begin":587,"end":592},"obj":"Gene"},{"id":"900","span":{"begin":27,"end":35},"obj":"Species"},{"id":"901","span":{"begin":70,"end":78},"obj":"Species"},{"id":"902","span":{"begin":142,"end":150},"obj":"Species"},{"id":"903","span":{"begin":88,"end":106},"obj":"Chemical"},{"id":"904","span":{"begin":185,"end":203},"obj":"Chemical"},{"id":"905","span":{"begin":292,"end":298},"obj":"Chemical"},{"id":"906","span":{"begin":48,"end":56},"obj":"Disease"},{"id":"907","span":{"begin":271,"end":276},"obj":"Disease"},{"id":"908","span":{"begin":365,"end":371},"obj":"Disease"},{"id":"909","span":{"begin":408,"end":413},"obj":"Disease"}],"attributes":[{"id":"A896","pred":"tao:has_database_id","subj":"896","obj":"Gene:3558"},{"id":"A897","pred":"tao:has_database_id","subj":"897","obj":"Gene:3565"},{"id":"A898","pred":"tao:has_database_id","subj":"898","obj":"Gene:3569"},{"id":"A899","pred":"tao:has_database_id","subj":"899","obj":"Gene:3586"},{"id":"A900","pred":"tao:has_database_id","subj":"900","obj":"Tax:9606"},{"id":"A901","pred":"tao:has_database_id","subj":"901","obj":"Tax:9606"},{"id":"A902","pred":"tao:has_database_id","subj":"902","obj":"Tax:9606"},{"id":"A903","pred":"tao:has_database_id","subj":"903","obj":"MESH:D008775"},{"id":"A904","pred":"tao:has_database_id","subj":"904","obj":"MESH:D008775"},{"id":"A905","pred":"tao:has_database_id","subj":"905","obj":"MESH:D010100"},{"id":"A906","pred":"tao:has_database_id","subj":"906","obj":"MESH:C000657245"},{"id":"A907","pred":"tao:has_database_id","subj":"907","obj":"MESH:D005334"},{"id":"A908","pred":"tao:has_database_id","subj":"908","obj":"MESH:D003643"},{"id":"A909","pred":"tao:has_database_id","subj":"909","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T180","span":{"begin":315,"end":319},"obj":"Body_part"},{"id":"T181","span":{"begin":516,"end":526},"obj":"Body_part"},{"id":"T182","span":{"begin":534,"end":542},"obj":"Body_part"},{"id":"T183","span":{"begin":554,"end":563},"obj":"Body_part"},{"id":"T184","span":{"begin":565,"end":569},"obj":"Body_part"}],"attributes":[{"id":"A180","pred":"fma_id","subj":"T180","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A181","pred":"fma_id","subj":"T181","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A182","pred":"fma_id","subj":"T182","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A183","pred":"fma_id","subj":"T183","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A184","pred":"fma_id","subj":"T184","obj":"http://purl.org/sig/ont/fma/fma84051"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T26","span":{"begin":315,"end":319},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T190","span":{"begin":48,"end":56},"obj":"Disease"}],"attributes":[{"id":"A190","pred":"mondo_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T290","span":{"begin":315,"end":319},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T291","span":{"begin":315,"end":319},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T292","span":{"begin":534,"end":542},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T293","span":{"begin":565,"end":569},"obj":"http://purl.obolibrary.org/obo/PR_000001379"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T199","span":{"begin":88,"end":106},"obj":"Chemical"},{"id":"T200","span":{"begin":185,"end":203},"obj":"Chemical"},{"id":"T201","span":{"begin":215,"end":220},"obj":"Chemical"},{"id":"T202","span":{"begin":292,"end":298},"obj":"Chemical"},{"id":"T203","span":{"begin":394,"end":399},"obj":"Chemical"},{"id":"T204","span":{"begin":428,"end":433},"obj":"Chemical"},{"id":"T205","span":{"begin":565,"end":567},"obj":"Chemical"},{"id":"T207","span":{"begin":571,"end":573},"obj":"Chemical"},{"id":"T209","span":{"begin":577,"end":579},"obj":"Chemical"},{"id":"T211","span":{"begin":587,"end":589},"obj":"Chemical"}],"attributes":[{"id":"A199","pred":"chebi_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/CHEBI_6888"},{"id":"A200","pred":"chebi_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/CHEBI_6888"},{"id":"A201","pred":"chebi_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A202","pred":"chebi_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A203","pred":"chebi_id","subj":"T203","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A204","pred":"chebi_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A205","pred":"chebi_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A206","pred":"chebi_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A207","pred":"chebi_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A208","pred":"chebi_id","subj":"T207","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A209","pred":"chebi_id","subj":"T209","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A210","pred":"chebi_id","subj":"T209","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A211","pred":"chebi_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A212","pred":"chebi_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-MedDRA","denotations":[{"id":"T25","span":{"begin":292,"end":309},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T26","span":{"begin":516,"end":532},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"},{"id":"T27","span":{"begin":534,"end":548},"obj":"http://purl.bioontology.org/ontology/MEDDRA/10022891"}],"attributes":[{"id":"A25","pred":"meddra_id","subj":"T25","obj":"http://purl.bioontology.org/ontology/MEDDRA/10033316"},{"id":"A26","pred":"meddra_id","subj":"T26","obj":"http://purl.bioontology.org/ontology/MEDDRA/10025251"},{"id":"A27","pred":"meddra_id","subj":"T27","obj":"http://purl.bioontology.org/ontology/MEDDRA/10027876"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T120","span":{"begin":261,"end":269},"obj":"http://purl.obolibrary.org/obo/OGMS_0000020"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T130","span":{"begin":88,"end":106},"obj":"Chemical"},{"id":"T131","span":{"begin":185,"end":203},"obj":"Chemical"},{"id":"T132","span":{"begin":292,"end":298},"obj":"Chemical"}],"attributes":[{"id":"A130","pred":"chebi_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/CHEBI_6888"},{"id":"A131","pred":"chebi_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/CHEBI_6888"},{"id":"A132","pred":"chebi_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-NCBITaxon","denotations":[{"id":"T235","span":{"begin":48,"end":56},"obj":"Species"}],"attributes":[{"id":"A235","pred":"ncbi_taxonomy_id","subj":"T235","obj":"NCBItxid:2697049"}],"namespaces":[{"prefix":"NCBItxid","uri":"http://purl.bioontology.org/ontology/NCBITAXON/"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T207","span":{"begin":0,"end":204},"obj":"Sentence"},{"id":"T208","span":{"begin":205,"end":351},"obj":"Sentence"},{"id":"T209","span":{"begin":352,"end":434},"obj":"Sentence"},{"id":"T210","span":{"begin":435,"end":619},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-UBERON","denotations":[{"id":"T26","span":{"begin":315,"end":319},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

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study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

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study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-MAT","denotations":[{"id":"T9","span":{"begin":315,"end":319},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T48","span":{"begin":408,"end":413},"obj":"http://purl.obolibrary.org/obo/GO_0016265"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T180","span":{"begin":315,"end":319},"obj":"Body_part"},{"id":"T181","span":{"begin":516,"end":526},"obj":"Body_part"},{"id":"T182","span":{"begin":534,"end":542},"obj":"Body_part"},{"id":"T183","span":{"begin":554,"end":563},"obj":"Body_part"},{"id":"T184","span":{"begin":565,"end":569},"obj":"Body_part"}],"attributes":[{"id":"A180","pred":"fma_id","subj":"T180","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A181","pred":"fma_id","subj":"T181","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A182","pred":"fma_id","subj":"T182","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A183","pred":"fma_id","subj":"T183","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A184","pred":"fma_id","subj":"T184","obj":"http://purl.org/sig/ont/fma/fma84051"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T180","span":{"begin":48,"end":56},"obj":"Disease"}],"attributes":[{"id":"A180","pred":"mondo_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sample-PD-HP","denotations":[{"id":"T15","span":{"begin":271,"end":276},"obj":"Phenotype"}],"attributes":[{"id":"A15","pred":"hp_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/HP_0001945"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-sentences","denotations":[{"id":"T207","span":{"begin":0,"end":204},"obj":"Sentence"},{"id":"T208","span":{"begin":205,"end":351},"obj":"Sentence"},{"id":"T209","span":{"begin":352,"end":434},"obj":"Sentence"},{"id":"T210","span":{"begin":435,"end":619},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T16","span":{"begin":271,"end":276},"obj":"Phenotype"}],"attributes":[{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0001945"}],"text":"The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone. The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging. However, two deaths occurred in the first group and one death in the second group. Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment."}