> top > docs > PMC:7205724 > spans > 23261-26102 > annotations

PMC:7205724 / 23261-26102 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
817 66-78 Disease denotes inflammation MESH:D007249
820 266-285 Disease denotes autoimmune diseases MESH:D001327
821 533-551 Disease denotes hyper inflammation MESH:D007249
823 730-738 Disease denotes COVID-19 MESH:C000657245
853 1853-1860 Gene denotes TMPRSS2 Gene:103219191
854 1987-1994 Gene denotes TMPRSS2 Gene:7113
855 900-908 Species denotes MERS-CoV Tax:1335626
856 1083-1088 Species denotes human Tax:9606
857 1089-1102 Species denotes coronaviruses Tax:11118
858 1126-1134 Species denotes SARS-CoV Tax:694009
859 1281-1308 Species denotes respiratory syncytial virus Tax:12814
860 1318-1326 Species denotes MERS-CoV Tax:1335626
861 1485-1493 Species denotes MERS-CoV Tax:1335626
862 1566-1574 Species denotes MERS-CoV Tax:1335626
863 1584-1593 Species denotes SARS-CoV2 Tax:2697049
864 1895-1904 Species denotes SARS-CoV2 Tax:2697049
865 1267-1276 Species denotes influenza Tax:11309
866 805-816 Chemical denotes ciclesonide MESH:C120481
867 818-827 Chemical denotes cortisone MESH:D003348
868 829-841 Chemical denotes prednisolone MESH:D011239
869 843-856 Chemical denotes dexamethasone MESH:D003907
870 862-873 Chemical denotes fluticasone MESH:D000068298
871 945-956 Chemical denotes ciclesonide MESH:C120481
872 1008-1019 Chemical denotes ciclesonide MESH:C120481
873 1396-1407 Chemical denotes ciclesonide MESH:C120481
874 1497-1508 Chemical denotes ciclesonide MESH:C120481
875 1510-1520 Chemical denotes Mometasone MESH:D000068656
876 1605-1616 Chemical denotes ciclesonide MESH:C120481
877 1618-1628 Chemical denotes mometasone MESH:D000068656
878 1634-1643 Chemical denotes lopinavir MESH:D061466
879 1757-1763 Chemical denotes serine MESH:D012694
880 1791-1801 Chemical denotes nafamostat MESH:C032855
881 1112-1121 CellLine denotes HCoV-229E CVCL:D748
896 2582-2586 Gene denotes IL-2 Gene:3558
897 2588-2592 Gene denotes IL-4 Gene:3565
898 2594-2598 Gene denotes IL-6 Gene:3569
899 2604-2609 Gene denotes IL-10 Gene:3586
900 2044-2052 Species denotes patients Tax:9606
901 2087-2095 Species denotes patients Tax:9606
902 2159-2167 Species denotes patients Tax:9606
903 2105-2123 Chemical denotes methylprednisolone MESH:D008775
904 2202-2220 Chemical denotes methylprednisolone MESH:D008775
905 2309-2315 Chemical denotes oxygen MESH:D010100
906 2065-2073 Disease denotes COVID-19 MESH:C000657245
907 2288-2293 Disease denotes fever MESH:D005334
908 2382-2388 Disease denotes deaths MESH:D003643
909 2425-2430 Disease denotes death MESH:D003643
914 2662-2669 Species denotes patient Tax:9606
915 2697-2715 Chemical denotes methylprednisolone MESH:D008775
916 2675-2683 Disease denotes COVID-19 MESH:C000657245
917 2797-2816 Disease denotes respiratory failure MESH:D012131

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T167 471-484 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T168 570-574 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T169 1164-1167 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T170 1248-1251 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T171 1344-1351 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T172 1412-1422 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T173 1757-1763 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T174 1818-1823 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T175 1834-1839 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 1918-1922 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T177 1945-1954 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T178 1995-2007 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T179 1995-1999 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T180 2332-2336 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T181 2533-2543 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T182 2551-2559 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T183 2571-2580 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T184 2582-2586 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T24 471-484 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T25 570-574 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T26 2332-2336 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T181 66-78 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T182 266-285 Disease denotes autoimmune diseases http://purl.obolibrary.org/obo/MONDO_0007179
T183 539-551 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T184 730-738 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T185 1126-1134 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T186 1175-1182 Disease denotes rubella http://purl.obolibrary.org/obo/MONDO_0004656
T187 1267-1276 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T188 1584-1588 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T189 1895-1899 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T190 2065-2073 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T191 2675-2683 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T192 2797-2816 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T272 131-132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T273 184-185 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T274 471-484 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T275 649-654 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T276 1028-1029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T277 1083-1088 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T278 1168-1173 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T279 1183-1188 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T280 1252-1259 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T281 1303-1308 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T282 1328-1329 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T283 1686-1687 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T284 1818-1823 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T285 1829-1833 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T286 1829-1833 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T287 1834-1839 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T288 1918-1922 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T289 1995-1999 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T290 2332-2336 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T291 2332-2336 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T292 2551-2559 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T293 2582-2586 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T294 2646-2647 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T175 318-333 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T176 402-416 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T177 417-422 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T178 432-447 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T179 508-523 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T180 789-804 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T181 818-827 Chemical denotes cortisone http://purl.obolibrary.org/obo/CHEBI_16962
T182 829-841 Chemical denotes prednisolone http://purl.obolibrary.org/obo/CHEBI_8378
T183 843-856 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T184 862-873 Chemical denotes fluticasone http://purl.obolibrary.org/obo/CHEBI_5134
T185 1344-1351 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T186 1412-1422 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T187 1412-1417 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T188 1418-1422 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T189 1510-1520 Chemical denotes Mometasone http://purl.obolibrary.org/obo/CHEBI_6970
T190 1618-1628 Chemical denotes mometasone http://purl.obolibrary.org/obo/CHEBI_6970
T191 1634-1643 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T192 1757-1783 Chemical denotes serine protease inhibitors http://purl.obolibrary.org/obo/CHEBI_64926
T193 1757-1763 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T194 1764-1783 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T196 1773-1783 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T197 1791-1801 Chemical denotes nafamostat http://purl.obolibrary.org/obo/CHEBI_135466
T198 1806-1814 Chemical denotes camostat http://purl.obolibrary.org/obo/CHEBI_135632
T199 2105-2123 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T200 2202-2220 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T201 2232-2237 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T202 2309-2315 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T203 2411-2416 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T204 2445-2450 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T205 2582-2584 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T207 2588-2590 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T209 2594-2596 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T211 2604-2606 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T213 2697-2715 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888

LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T24 754-766 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes investigated http://purl.bioontology.org/ontology/MEDDRA/10062026
T25 2309-2326 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes oxygen saturation http://purl.bioontology.org/ontology/MEDDRA/10033316
T26 2533-2549 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes lymphocyte count http://purl.bioontology.org/ontology/MEDDRA/10025251
T27 2551-2565 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes monocyte count http://purl.bioontology.org/ontology/MEDDRA/10027876

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T103 277-285 http://purl.obolibrary.org/obo/OGMS_0000031 denotes diseases
T104 584-600 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T105 624-628 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T106 649-654 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T107 881-892 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T108 989-1000 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T109 1062-1073 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T110 1168-1173 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T111 1183-1188 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T112 1217-1228 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T113 1252-1259 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T114 1303-1308 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T115 1671-1682 http://purl.obolibrary.org/obo/IDO_0000608 denotes replication
T116 1818-1823 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T117 1834-1839 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T118 1918-1922 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T119 1995-1999 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T120 2278-2286 http://purl.obolibrary.org/obo/OGMS_0000020 denotes symptoms
T121 2735-2749 http://purl.obolibrary.org/obo/OGMS_0000063 denotes disease course
T122 2735-2742 http://purl.obolibrary.org/obo/OGMS_0000031 denotes disease

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T111 318-333 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T112 402-416 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T113 432-447 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T114 508-523 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T115 789-804 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T116 818-827 Chemical denotes cortisone http://purl.obolibrary.org/obo/CHEBI_16962
T117 829-841 Chemical denotes prednisolone http://purl.obolibrary.org/obo/CHEBI_8378
T118 843-856 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T119 862-873 Chemical denotes fluticasone http://purl.obolibrary.org/obo/CHEBI_5134
T120 1164-1167 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T121 1248-1251 Chemical denotes RNA http://purl.obolibrary.org/obo/CHEBI_33697
T122 1344-1351 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T123 1412-1422 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T124 1510-1520 Chemical denotes Mometasone http://purl.obolibrary.org/obo/CHEBI_6970
T125 1618-1628 Chemical denotes mometasone http://purl.obolibrary.org/obo/CHEBI_6970
T126 1634-1643 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T127 1757-1763 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T128 1791-1801 Chemical denotes nafamostat http://purl.obolibrary.org/obo/CHEBI_135466
T129 1806-1814 Chemical denotes camostat http://purl.obolibrary.org/obo/CHEBI_135632
T130 2105-2123 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T131 2202-2220 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T132 2309-2315 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T133 2697-2715 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T221 730-738 Species denotes COVID-19 NCBItxid:2697049
T222 900-908 Species denotes MERS-CoV NCBItxid:1335626
T223 1083-1102 Species denotes human coronaviruses NCBItxid:694448
T224 1112-1121 Species denotes HCoV-229E NCBItxid:11137
T225 1126-1134 Species denotes SARS-CoV NCBItxid:694009
T226 1164-1173 Species denotes RNA virus NCBItxid:2559587
T227 1175-1188 Species denotes rubella virus NCBItxid:11041
T228 1232-1259 Species denotes negative-strand RNA viruses NCBItxid:2497569
T229 1281-1308 Species denotes respiratory syncytial virus NCBItxid:12814
T230 1318-1326 Species denotes MERS-CoV NCBItxid:1335626
T231 1485-1493 Species denotes MERS-CoV NCBItxid:1335626
T232 1566-1574 Species denotes MERS-CoV NCBItxid:1335626
T233 1584-1593 Species denotes SARS-CoV2 NCBItxid:2697049
T234 1895-1904 Species denotes SARS-CoV2 NCBItxid:2697049
T235 2065-2073 Species denotes COVID-19 NCBItxid:2697049
T236 2675-2683 Species denotes COVID-19 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T189 0-18 Sentence denotes 7 Corticosteroids
T190 20-36 Sentence denotes 7.1 Hypothesis:
T191 37-78 Sentence denotes Corticosteroids can modulate inflammation
T192 79-168 Sentence denotes Corticosteroids are commonly used for modulation of a variety of inflammatory conditions.
T193 169-286 Sentence denotes In addition to a daily regimen, they can be used in the form of pulse therapy to treat flares of autoimmune diseases.
T194 287-485 Sentence denotes However, caution in the use of corticosteroids is needed due to the potential serious side effects associated with corticosteroid drugs and that corticosteroids generally suppress the immune system.
T195 486-660 Sentence denotes The latter means that corticosteroids modulate hyper inflammation and, on the other hand, inhibit immune responses that are vital for the host defense against the virus [29].
T196 662-677 Sentence denotes 7.2 Rationale:
T197 678-738 Sentence denotes Corticosteroids might help accelerate recovery from COVID-19
T198 739-909 Sentence denotes The study [30] investigated the effect of inhaled corticosteroids ciclesonide, cortisone, prednisolone, dexamethasone, and fluticasone on the replication of the MERS-CoV.
T199 910-1001 Sentence denotes Among the four compounds, the only ciclesonide was capable of inhibiting viral replication.
T200 1002-1309 Sentence denotes Also, ciclesonide induced a significant inhibition of viral replication of other human coronaviruses, such as HCoV-229E and SARS-CoV, and another positive-strand RNA virus, rubella virus, while not affect the viral replication of negative-strand RNA viruses, e.g., influenza and respiratory syncytial virus.
T201 1310-1408 Sentence denotes For the MERS-CoV, a nonstructural protein 15 (NSP15) appeared to act as the target of ciclesonide.
T202 1409-1509 Sentence denotes An amino acid substitution in the NSP15 conferred resistance of the mutated MERS-CoV to ciclesonide.
T203 1510-1575 Sentence denotes Mometasone could help deal effectively with the mutated MERS-CoV.
T204 1576-1703 Sentence denotes For the SARS-CoV2, all three ciclesonide, mometasone, and lopinavir were able to inhibit viral replication to a similar degree.
T205 1704-1861 Sentence denotes Interestingly, their effect was more noticeable than serine protease inhibitors, e.g., nafamostat and camostat in cells that Vero cells that express TMPRSS2.
T206 1862-2016 Sentence denotes It indicates the tendency of the SARS-CoV2 to enter the cell through the cathepsin/endosomal pathway rather than through the TMPRSS2/cell surface pathway.
T207 2017-2221 Sentence denotes The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone.
T208 2222-2368 Sentence denotes The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging.
T209 2369-2451 Sentence denotes However, two deaths occurred in the first group and one death in the second group.
T210 2452-2636 Sentence denotes Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment.
T211 2637-2750 Sentence denotes There is a report of the patient with COVID-19 treated with methylprednisolone since day 8 of the disease course.
T212 2751-2841 Sentence denotes However, his situation worsened and developed respiratory failure and died on day 14 [32].

LitCovid-sample-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T24 471-484 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T25 570-574 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T26 2332-2336 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
817 66-78 Disease denotes inflammation MESH:D007249
820 266-285 Disease denotes autoimmune diseases MESH:D001327
821 533-551 Disease denotes hyper inflammation MESH:D007249
823 730-738 Disease denotes COVID-19 MESH:C000657245
866 805-816 Chemical denotes ciclesonide MESH:C120481
867 818-827 Chemical denotes cortisone MESH:D003348
868 829-841 Chemical denotes prednisolone MESH:D011239
869 843-856 Chemical denotes dexamethasone MESH:D003907
870 862-873 Chemical denotes fluticasone MESH:D000068298
855 900-908 Species denotes MERS-CoV Tax:1335626
871 945-956 Chemical denotes ciclesonide MESH:C120481
872 1008-1019 Chemical denotes ciclesonide MESH:C120481
856 1083-1088 Species denotes human Tax:9606
857 1089-1102 Species denotes coronaviruses Tax:11118
881 1112-1121 CellLine denotes HCoV-229E CVCL:D748
858 1126-1134 Species denotes SARS-CoV Tax:694009
865 1267-1276 Species denotes influenza Tax:11309
859 1281-1308 Species denotes respiratory syncytial virus Tax:12814
860 1318-1326 Species denotes MERS-CoV Tax:1335626
873 1396-1407 Chemical denotes ciclesonide MESH:C120481
861 1485-1493 Species denotes MERS-CoV Tax:1335626
874 1497-1508 Chemical denotes ciclesonide MESH:C120481
875 1510-1520 Chemical denotes Mometasone MESH:D000068656
862 1566-1574 Species denotes MERS-CoV Tax:1335626
863 1584-1593 Species denotes SARS-CoV2 Tax:2697049
876 1605-1616 Chemical denotes ciclesonide MESH:C120481
877 1618-1628 Chemical denotes mometasone MESH:D000068656
878 1634-1643 Chemical denotes lopinavir MESH:D061466
879 1757-1763 Chemical denotes serine MESH:D012694
880 1791-1801 Chemical denotes nafamostat MESH:C032855
853 1853-1860 Gene denotes TMPRSS2 Gene:103219191
864 1895-1904 Species denotes SARS-CoV2 Tax:2697049
854 1987-1994 Gene denotes TMPRSS2 Gene:7113
900 2044-2052 Species denotes patients Tax:9606
906 2065-2073 Disease denotes COVID-19 MESH:C000657245
901 2087-2095 Species denotes patients Tax:9606
903 2105-2123 Chemical denotes methylprednisolone MESH:D008775
902 2159-2167 Species denotes patients Tax:9606
904 2202-2220 Chemical denotes methylprednisolone MESH:D008775
907 2288-2293 Disease denotes fever MESH:D005334
905 2309-2315 Chemical denotes oxygen MESH:D010100
908 2382-2388 Disease denotes deaths MESH:D003643
909 2425-2430 Disease denotes death MESH:D003643
896 2582-2586 Gene denotes IL-2 Gene:3558
897 2588-2592 Gene denotes IL-4 Gene:3565
898 2594-2598 Gene denotes IL-6 Gene:3569
899 2604-2609 Gene denotes IL-10 Gene:3586
914 2662-2669 Species denotes patient Tax:9606
916 2675-2683 Disease denotes COVID-19 MESH:C000657245
915 2697-2715 Chemical denotes methylprednisolone MESH:D008775
917 2797-2816 Disease denotes respiratory failure MESH:D012131

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T2261 1330-1354 Protein denotes nonstructural protein 15 https://www.uniprot.org/uniprot/Q80E51|https://www.uniprot.org/uniprot/Q80BV8|https://www.uniprot.org/uniprot/Q80BV7|https://www.uniprot.org/uniprot/Q808C0|https://www.uniprot.org/uniprot/Q7T697|https://www.uniprot.org/uniprot/Q6WGN0|https://www.uniprot.org/uniprot/P59641|https://www.uniprot.org/uniprot/P0DTD1|https://www.uniprot.org/uniprot/P0C6X7
T2270 1356-1361 Protein denotes NSP15 https://www.uniprot.org/uniprot/Q80E51
T2271 1443-1448 Protein denotes NSP15 https://www.uniprot.org/uniprot/Q80E51
T2272 1757-1783 Protein denotes serine protease inhibitors https://www.uniprot.org/uniprot/Q6J201
T2273 2582-2586 Protein denotes IL-2 https://www.uniprot.org/uniprot/Q9XT84|https://www.uniprot.org/uniprot/Q9XT83|https://www.uniprot.org/uniprot/Q9XS38|https://www.uniprot.org/uniprot/Q95MP4|https://www.uniprot.org/uniprot/Q95KP3|https://www.uniprot.org/uniprot/Q8MKH2|https://www.uniprot.org/uniprot/Q8HYR7|https://www.uniprot.org/uniprot/Q865Y1|https://www.uniprot.org/uniprot/Q865X2|https://www.uniprot.org/uniprot/Q7JFM5|https://www.uniprot.org/uniprot/Q7JFM4|https://www.uniprot.org/uniprot/Q7JFM3|https://www.uniprot.org/uniprot/Q7JFM2|https://www.uniprot.org/uniprot/Q791T3|https://www.uniprot.org/uniprot/Q5QT38|https://www.uniprot.org/uniprot/Q5PXD0|https://www.uniprot.org/uniprot/Q5MBA8|https://www.uniprot.org/uniprot/Q4U313|https://www.uniprot.org/uniprot/Q2PE78|https://www.uniprot.org/uniprot/Q2PE47|https://www.uniprot.org/uniprot/Q29615|https://www.uniprot.org/uniprot/Q29416|https://www.uniprot.org/uniprot/Q28249|https://www.uniprot.org/uniprot/Q25BC3|https://www.uniprot.org/uniprot/Q1WM29|https://www.uniprot.org/uniprot/Q0MS74|https://www.uniprot.org/uniprot/Q0MS71|https://www.uniprot.org/uniprot/Q08867|https://www.uniprot.org/uniprot/Q08081|https://www.uniprot.org/uniprot/Q07885|https://www.uniprot.org/uniprot/P97945|https://www.uniprot.org/uniprot/P79156|https://www.uniprot.org/uniprot/P70463|https://www.uniprot.org/uniprot/P70462|https://www.uniprot.org/uniprot/P68291|https://www.uniprot.org/uniprot/P68290|https://www.uniprot.org/uniprot/P60569|https://www.uniprot.org/uniprot/P60568|https://www.uniprot.org/uniprot/P51747|https://www.uniprot.org/uniprot/P51498|https://www.uniprot.org/uniprot/P46649|https://www.uniprot.org/uniprot/P37997|https://www.uniprot.org/uniprot/P36835|https://www.uniprot.org/uniprot/P26891|https://www.uniprot.org/uniprot/P19114|https://www.uniprot.org/uniprot/P17108|https://www.uniprot.org/uniprot/P05016|https://www.uniprot.org/uniprot/P04351|https://www.uniprot.org/uniprot/P01585|https://www.uniprot.org/uniprot/O97513|https://www.uniprot.org/uniprot/O77620|https://www.uniprot.org/uniprot/O62641|https://www.uniprot.org/uniprot/A9QWQ6|https://www.uniprot.org/uniprot/A0MZP6|https://www.uniprot.org/uniprot/A0MZP0
T2328 2588-2592 Protein denotes IL-4 https://www.uniprot.org/uniprot/Q9XS58|https://www.uniprot.org/uniprot/Q9MZR8|https://www.uniprot.org/uniprot/Q9GL85|https://www.uniprot.org/uniprot/Q95MZ6|https://www.uniprot.org/uniprot/Q8MKE6|https://www.uniprot.org/uniprot/Q8HYB1|https://www.uniprot.org/uniprot/Q865Y0|https://www.uniprot.org/uniprot/Q865X5|https://www.uniprot.org/uniprot/Q7YS71|https://www.uniprot.org/uniprot/Q6YL20|https://www.uniprot.org/uniprot/Q6NZ77|https://www.uniprot.org/uniprot/Q60440|https://www.uniprot.org/uniprot/Q58M18|https://www.uniprot.org/uniprot/Q3S4V6|https://www.uniprot.org/uniprot/Q2PE74|https://www.uniprot.org/uniprot/Q29054|https://www.uniprot.org/uniprot/Q14630|https://www.uniprot.org/uniprot/Q0MS73|https://www.uniprot.org/uniprot/Q0MS70|https://www.uniprot.org/uniprot/Q04745|https://www.uniprot.org/uniprot/P79339|https://www.uniprot.org/uniprot/P79170|https://www.uniprot.org/uniprot/P79155|https://www.uniprot.org/uniprot/P55030|https://www.uniprot.org/uniprot/P51744|https://www.uniprot.org/uniprot/P51492|https://www.uniprot.org/uniprot/P47966|https://www.uniprot.org/uniprot/P46652|https://www.uniprot.org/uniprot/P42202|https://www.uniprot.org/uniprot/P30368|https://www.uniprot.org/uniprot/P30367|https://www.uniprot.org/uniprot/P20096|https://www.uniprot.org/uniprot/P07750|https://www.uniprot.org/uniprot/P05112|https://www.uniprot.org/uniprot/O77762|https://www.uniprot.org/uniprot/O70330|https://www.uniprot.org/uniprot/O62774|https://www.uniprot.org/uniprot/O46393|https://www.uniprot.org/uniprot/A9QWQ7|https://www.uniprot.org/uniprot/A1E293
T2368 2594-2598 Protein denotes IL-6 https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0
T2412 2604-2609 Protein denotes IL-10 https://www.uniprot.org/uniprot/Q9Z1Y5|https://www.uniprot.org/uniprot/Q9TSJ7|https://www.uniprot.org/uniprot/Q9TSJ4|https://www.uniprot.org/uniprot/Q9JHK7|https://www.uniprot.org/uniprot/Q8MKG9|https://www.uniprot.org/uniprot/Q865X4|https://www.uniprot.org/uniprot/Q6A2H5|https://www.uniprot.org/uniprot/Q6A2H4|https://www.uniprot.org/uniprot/Q63263|https://www.uniprot.org/uniprot/Q5Q0V6|https://www.uniprot.org/uniprot/Q2PE73|https://www.uniprot.org/uniprot/Q29408|https://www.uniprot.org/uniprot/Q29055|https://www.uniprot.org/uniprot/Q28374|https://www.uniprot.org/uniprot/Q25BC1|https://www.uniprot.org/uniprot/Q1W5D6|https://www.uniprot.org/uniprot/Q0Z972|https://www.uniprot.org/uniprot/Q0VBJ1|https://www.uniprot.org/uniprot/P79338|https://www.uniprot.org/uniprot/P55029|https://www.uniprot.org/uniprot/P51746|https://www.uniprot.org/uniprot/P51497|https://www.uniprot.org/uniprot/P51496|https://www.uniprot.org/uniprot/P48411|https://www.uniprot.org/uniprot/P47965|https://www.uniprot.org/uniprot/P46651|https://www.uniprot.org/uniprot/P43480|https://www.uniprot.org/uniprot/P29456|https://www.uniprot.org/uniprot/P22301|https://www.uniprot.org/uniprot/P18893|https://www.uniprot.org/uniprot/O97798|https://www.uniprot.org/uniprot/O46673|https://www.uniprot.org/uniprot/A9QWR2|https://www.uniprot.org/uniprot/A2T6Z6

LitCovid-sample-Enju

Id Subject Object Predicate Lexical cue
T24370 0-1 CD denotes 7
T36802 3-18 NNS denotes Corticosteroids
T3294 20-23 CD denotes 7.1
T91345 25-35 NN denotes Hypothesis
T83198 35-36 -COLON- denotes :
T5476 37-52 NNS denotes Corticosteroids
T19383 53-56 MD denotes can
T18906 57-65 VB denotes modulate
T94029 66-78 NN denotes inflammation
T27658 79-94 NNS denotes Corticosteroids
T8138 95-98 VBP denotes are
T91474 99-107 RB denotes commonly
T89187 108-112 VBN denotes used
T38824 113-116 IN denotes for
T21445 117-127 NN denotes modulation
T58316 128-130 IN denotes of
T58021 131-132 DT denotes a
T37655 133-140 NN denotes variety
T87627 141-143 IN denotes of
T8391 144-156 JJ denotes inflammatory
T71073 157-167 NNS denotes conditions
T68994 169-171 IN denotes In
T59818 172-180 NN denotes addition
T18282 181-183 TO denotes to
T76082 184-185 DT denotes a
T38966 186-191 JJ denotes daily
T35672 192-199 NN denotes regimen
T41748 199-200 -COMMA- denotes ,
T45789 201-205 PRP denotes they
T91069 206-209 MD denotes can
T84858 210-212 VB denotes be
T11971 213-217 VBN denotes used
T91181 218-220 IN denotes in
T55573 221-224 DT denotes the
T52866 225-229 NN denotes form
T8605 230-232 IN denotes of
T21111 233-238 NN denotes pulse
T43357 239-246 NN denotes therapy
T46430 247-249 TO denotes to
T90499 250-255 VB denotes treat
T36198 256-262 NNS denotes flares
T16735 263-265 IN denotes of
T37577 266-276 JJ denotes autoimmune
T82392 277-285 NNS denotes diseases
T8787 287-294 RB denotes However
T74715 294-295 -COMMA- denotes ,
T63832 296-303 NN denotes caution
T88619 304-306 IN denotes in
T72548 307-310 DT denotes the
T74757 311-314 NN denotes use
T50691 315-317 IN denotes of
T75348 318-333 NNS denotes corticosteroids
T98869 334-336 VBZ denotes is
T37602 337-343 VBN denotes needed
T93826 344-347 IN denotes due
T27767 348-350 TO denotes to
T91545 351-354 DT denotes the
T30802 355-364 JJ denotes potential
T82688 365-372 JJ denotes serious
T84923 373-377 NN denotes side
T90339 378-385 NNS denotes effects
T67748 386-396 VBN denotes associated
T22188 397-401 IN denotes with
T5158 402-416 NN denotes corticosteroid
T29681 417-422 NNS denotes drugs
T1981 423-426 CC denotes and
T7707 427-431 IN denotes that
T73209 432-447 NNS denotes corticosteroids
T32353 448-457 RB denotes generally
T32990 458-466 VBP denotes suppress
T84727 467-470 DT denotes the
T72594 471-477 JJ denotes immune
T82578 478-484 NN denotes system
T98970 486-489 DT denotes The
T73202 490-496 JJ denotes latter
T49682 497-502 VBZ denotes means
T56698 503-507 IN denotes that
T44497 508-523 NNS denotes corticosteroids
T44722 524-532 VBP denotes modulate
T39029 533-538 NN denotes hyper
T14674 539-551 NN denotes inflammation
T31300 552-555 CC denotes and
T40275 555-556 -COMMA- denotes ,
T84174 557-559 IN denotes on
T84917 560-563 DT denotes the
T41471 564-569 JJ denotes other
T79253 570-574 NN denotes hand
T80094 574-575 -COMMA- denotes ,
T14361 576-583 VBP denotes inhibit
T92448 584-590 JJ denotes immune
T32652 591-600 NNS denotes responses
T58197 601-605 WDT denotes that
T6432 606-609 VBP denotes are
T65734 610-615 JJ denotes vital
T7857 616-619 IN denotes for
T27355 620-623 DT denotes the
T81023 624-628 NN denotes host
T39598 629-636 NN denotes defense
T97712 637-644 IN denotes against
T6736 645-648 DT denotes the
T59893 649-654 NN denotes virus
T48542 655-656 -LRB- denotes [
T9013 656-658 CD denotes 29
T33036 658-659 -RRB- denotes ]
T37227 662-665 CD denotes 7.2
T83170 667-676 NNP denotes Rationale
T22490 676-677 -COLON- denotes :
T92502 678-693 NNS denotes Corticosteroids
T30425 694-699 MD denotes might
T17782 700-704 VB denotes help
T8496 705-715 VB denotes accelerate
T16617 716-724 NN denotes recovery
T39745 725-729 IN denotes from
T7154 730-738 NN denotes COVID-19
T19799 739-742 DT denotes The
T20594 743-748 NN denotes study
T82079 749-750 -LRB- denotes [
T66365 750-752 CD denotes 30
T51925 752-753 -RRB- denotes ]
T58773 754-766 VBD denotes investigated
T62943 767-770 DT denotes the
T17766 771-777 NN denotes effect
T91507 778-780 IN denotes of
T41721 781-788 VBN denotes inhaled
T68865 789-804 NNS denotes corticosteroids
T72129 805-816 NN denotes ciclesonide
T75975 816-817 -COMMA- denotes ,
T94153 818-827 NN denotes cortisone
T58635 827-828 -COMMA- denotes ,
T32129 829-841 NN denotes prednisolone
T52544 841-842 -COMMA- denotes ,
T7734 843-856 NN denotes dexamethasone
T48772 856-857 -COMMA- denotes ,
T59239 858-861 CC denotes and
T36302 862-873 NN denotes fluticasone
T2290 874-876 IN denotes on
T42645 877-880 DT denotes the
T67274 881-892 NN denotes replication
T25492 893-895 IN denotes of
T52796 896-899 DT denotes the
T27491 900-908 NN denotes MERS-CoV
T5267 910-915 IN denotes Among
T36393 916-919 DT denotes the
T1788 920-924 CD denotes four
T60636 925-934 NNS denotes compounds
T50162 934-935 -COMMA- denotes ,
T78874 936-939 DT denotes the
T22199 940-944 JJ denotes only
T45806 945-956 NN denotes ciclesonide
T86672 957-960 VBD denotes was
T12794 961-968 JJ denotes capable
T91797 969-971 IN denotes of
T13593 972-982 VBG denotes inhibiting
T5717 983-988 JJ denotes viral
T7401 989-1000 NN denotes replication
T65340 1002-1006 RB denotes Also
T92623 1006-1007 -COMMA- denotes ,
T81617 1008-1019 NN denotes ciclesonide
T95958 1020-1027 VBD denotes induced
T85366 1028-1029 DT denotes a
T21714 1030-1041 JJ denotes significant
T15429 1042-1052 NN denotes inhibition
T16699 1053-1055 IN denotes of
T25584 1056-1061 JJ denotes viral
T73696 1062-1073 NN denotes replication
T7458 1074-1076 IN denotes of
T20174 1077-1082 JJ denotes other
T58259 1083-1088 JJ denotes human
T40953 1089-1102 NNS denotes coronaviruses
T84867 1102-1103 -COMMA- denotes ,
T83672 1104-1108 JJ denotes such
T19443 1109-1111 IN denotes as
T95806 1112-1121 NN denotes HCoV-229E
T84685 1122-1125 CC denotes and
T17277 1126-1134 NN denotes SARS-CoV
T94349 1134-1135 -COMMA- denotes ,
T72578 1136-1139 CC denotes and
T26171 1140-1147 DT denotes another
T39629 1148-1163 JJ denotes positive-strand
T10581 1164-1167 NN denotes RNA
T42602 1168-1173 NN denotes virus
T70474 1173-1174 -COMMA- denotes ,
T82553 1175-1182 NN denotes rubella
T68058 1183-1188 NN denotes virus
T24019 1188-1189 -COMMA- denotes ,
T62462 1190-1195 IN denotes while
T32300 1196-1199 RB denotes not
T38146 1200-1206 VB denotes affect
T72944 1207-1210 DT denotes the
T97423 1211-1216 JJ denotes viral
T43382 1217-1228 NN denotes replication
T16861 1229-1231 IN denotes of
T53501 1232-1247 JJ denotes negative-strand
T3387 1248-1251 NN denotes RNA
T51732 1252-1259 NNS denotes viruses
T35282 1259-1260 -COMMA- denotes ,
T32607 1261-1265 FW denotes e.g.
T24756 1265-1266 -COMMA- denotes ,
T29751 1267-1276 NN denotes influenza
T16801 1277-1280 CC denotes and
T19789 1281-1292 JJ denotes respiratory
T17323 1293-1302 JJ denotes syncytial
T9582 1303-1308 NN denotes virus
T55931 1310-1313 IN denotes For
T42084 1314-1317 DT denotes the
T92915 1318-1326 NN denotes MERS-CoV
T45016 1326-1327 -COMMA- denotes ,
T62094 1328-1329 DT denotes a
T52727 1330-1343 JJ denotes nonstructural
T37738 1344-1351 NN denotes protein
T44869 1352-1354 CD denotes 15
T12678 1355-1356 -LRB- denotes (
T67952 1356-1361 NN denotes NSP15
T62960 1361-1362 -RRB- denotes )
T99202 1363-1371 VBD denotes appeared
T16450 1372-1374 TO denotes to
T75671 1375-1378 VB denotes act
T10168 1379-1381 IN denotes as
T75263 1382-1385 DT denotes the
T95644 1386-1392 NN denotes target
T19735 1393-1395 IN denotes of
T45429 1396-1407 NN denotes ciclesonide
T28790 1409-1411 DT denotes An
T72966 1412-1417 JJ denotes amino
T10430 1418-1422 NN denotes acid
T13644 1423-1435 NN denotes substitution
T66951 1436-1438 IN denotes in
T16733 1439-1442 DT denotes the
T82047 1443-1448 NN denotes NSP15
T5298 1449-1458 VBD denotes conferred
T82196 1459-1469 NN denotes resistance
T91861 1470-1472 IN denotes of
T16541 1473-1476 DT denotes the
T11735 1477-1484 VBN denotes mutated
T77495 1485-1493 NN denotes MERS-CoV
T54348 1494-1496 TO denotes to
T98167 1497-1508 NN denotes ciclesonide
T36698 1510-1520 NN denotes Mometasone
T83057 1521-1526 MD denotes could
T32973 1527-1531 VB denotes help
T81462 1532-1536 VB denotes deal
T7177 1537-1548 RB denotes effectively
T91822 1549-1553 IN denotes with
T40647 1554-1557 DT denotes the
T69218 1558-1565 VBN denotes mutated
T94051 1566-1574 NN denotes MERS-CoV
T94597 1576-1579 IN denotes For
T52862 1580-1583 DT denotes the
T49143 1584-1593 NN denotes SARS-CoV2
T76216 1593-1594 -COMMA- denotes ,
T48579 1595-1598 DT denotes all
T87735 1599-1604 CD denotes three
T54792 1605-1616 NN denotes ciclesonide
T41003 1616-1617 -COMMA- denotes ,
T64594 1618-1628 NN denotes mometasone
T89636 1628-1629 -COMMA- denotes ,
T45337 1630-1633 CC denotes and
T31426 1634-1643 NN denotes lopinavir
T30995 1644-1648 VBD denotes were
T47275 1649-1653 JJ denotes able
T43506 1654-1656 TO denotes to
T13737 1657-1664 VB denotes inhibit
T48184 1665-1670 JJ denotes viral
T45532 1671-1682 NN denotes replication
T78456 1683-1685 TO denotes to
T84667 1686-1687 DT denotes a
T50127 1688-1695 JJ denotes similar
T63329 1696-1702 NN denotes degree
T13824 1704-1717 RB denotes Interestingly
T97722 1717-1718 -COMMA- denotes ,
T32551 1719-1724 PRP-DOLLAR- denotes their
T29877 1725-1731 NN denotes effect
T26799 1732-1735 VBD denotes was
T38163 1736-1740 RBR denotes more
T71857 1741-1751 JJ denotes noticeable
T13399 1752-1756 IN denotes than
T61277 1757-1763 NN denotes serine
T95334 1764-1772 NN denotes protease
T18879 1773-1783 NNS denotes inhibitors
T2889 1783-1784 -COMMA- denotes ,
T73448 1785-1789 FW denotes e.g.
T12218 1789-1790 -COMMA- denotes ,
T97193 1791-1801 NN denotes nafamostat
T84364 1802-1805 CC denotes and
T56231 1806-1814 NN denotes camostat
T36295 1815-1817 IN denotes in
T50002 1818-1823 NNS denotes cells
T41374 1824-1828 WDT denotes that
T64051 1829-1833 NN denotes Vero
T69995 1834-1839 NNS denotes cells
T3328 1840-1844 WDT denotes that
T80806 1845-1852 VBP denotes express
T14927 1853-1860 NN denotes TMPRSS2
T77594 1862-1864 PRP denotes It
T50088 1865-1874 VBZ denotes indicates
T80437 1875-1878 DT denotes the
T11181 1879-1887 NN denotes tendency
T22059 1888-1890 IN denotes of
T93173 1891-1894 DT denotes the
T10513 1895-1904 NN denotes SARS-CoV2
T35356 1905-1907 TO denotes to
T95799 1908-1913 VB denotes enter
T54387 1914-1917 DT denotes the
T81737 1918-1922 NN denotes cell
T49362 1923-1930 IN denotes through
T16554 1931-1934 DT denotes the
T7152 1935-1954 JJ denotes cathepsin/endosomal
T53710 1955-1962 NN denotes pathway
T21481 1963-1969 RB denotes rather
T71892 1970-1974 IN denotes than
T13882 1975-1982 IN denotes through
T1912 1983-1986 DT denotes the
T96928 1987-1999 NN denotes TMPRSS2/cell
T71956 2000-2007 NN denotes surface
T74893 2008-2015 NN denotes pathway
T35160 2017-2020 DT denotes The
T65117 2021-2026 NN denotes study
T45353 2027-2028 -LRB- denotes [
T58501 2028-2030 CD denotes 31
T88016 2030-2031 -RRB- denotes ]
T88407 2032-2040 VBD denotes included
T16300 2041-2043 CD denotes 46
T33446 2044-2052 NNS denotes patients
T87886 2053-2057 IN denotes with
T58994 2058-2064 JJ denotes severe
T97970 2065-2073 NN denotes COVID-19
T41758 2073-2074 -COMMA- denotes ,
T58135 2075-2077 IN denotes of
T85647 2078-2083 DT denotes these
T95602 2084-2086 CD denotes 26
T73561 2087-2095 NNS denotes patients
T76496 2096-2104 VBD denotes received
T42976 2105-2123 NN denotes methylprednisolone
T32544 2124-2125 -LRB- denotes (
T60914 2125-2136 NN denotes 1–2 mg/kg/d
T95632 2137-2140 IN denotes for
T23094 2141-2149 NNS denotes 5–7 days
T28841 2149-2150 -RRB- denotes )
T83750 2150-2151 -COMMA- denotes ,
T5759 2152-2155 CC denotes and
T23681 2156-2158 CD denotes 20
T13615 2159-2167 NNS denotes patients
T96732 2168-2176 VBD denotes received
T97501 2177-2185 JJ denotes standard
T84414 2186-2193 NN denotes therapy
T2990 2194-2201 IN denotes without
T83484 2202-2220 NN denotes methylprednisolone
T55303 2222-2225 DT denotes The
T42547 2226-2231 JJ denotes first
T58218 2232-2237 NN denotes group
T37085 2238-2246 VBD denotes achieved
T74264 2247-2253 JJR denotes faster
T54798 2254-2265 NN denotes improvement
T77136 2266-2268 IN denotes in
T46765 2269-2277 JJ denotes clinical
T98040 2278-2286 NNS denotes symptoms
T23999 2287-2288 -LRB- denotes (
T37402 2288-2293 NN denotes fever
T65661 2294-2297 CC denotes and
T89758 2298-2308 JJ denotes peripheral
T63703 2309-2315 NN denotes oxygen
T9527 2316-2326 NN denotes saturation
T5300 2326-2327 -RRB- denotes )
T34896 2328-2331 CC denotes and
T9982 2332-2336 NN denotes lung
T64673 2337-2344 NNS denotes lesions
T90980 2345-2353 VBN denotes detected
T16483 2354-2356 IN denotes by
T31403 2357-2359 NN denotes CT
T8195 2360-2367 NN denotes imaging
T7710 2369-2376 RB denotes However
T57863 2376-2377 -COMMA- denotes ,
T19219 2378-2381 CD denotes two
T43356 2382-2388 NNS denotes deaths
T32769 2389-2397 VBD denotes occurred
T5412 2398-2400 IN denotes in
T52171 2401-2404 DT denotes the
T5683 2405-2410 JJ denotes first
T18985 2411-2416 NN denotes group
T72564 2417-2420 CC denotes and
T66890 2421-2424 CD denotes one
T21460 2425-2430 NN denotes death
T49866 2431-2433 IN denotes in
T26278 2434-2437 DT denotes the
T96270 2438-2444 JJ denotes second
T89439 2445-2450 NN denotes group
T61059 2452-2460 RB denotes Moreover
T97295 2460-2461 -COMMA- denotes ,
T66784 2462-2465 DT denotes the
T32526 2466-2469 CD denotes two
T39437 2470-2476 NNS denotes groups
T87016 2477-2480 VBD denotes did
T42838 2481-2484 RB denotes not
T18576 2485-2491 VB denotes differ
T50188 2492-2494 IN denotes in
T80686 2495-2505 NN denotes laboratory
T16685 2506-2516 NNS denotes parameters
T92910 2516-2517 -COMMA- denotes ,
T79314 2518-2527 VBG denotes including
T58552 2528-2531 NNP denotes WBC
T52445 2531-2532 -COMMA- denotes ,
T19300 2533-2543 NN denotes lymphocyte
T50601 2544-2549 NN denotes count
T15065 2549-2550 -COMMA- denotes ,
T27527 2551-2559 NN denotes monocyte
T31332 2560-2565 NN denotes count
T62470 2565-2566 -COMMA- denotes ,
T39782 2567-2570 CC denotes and
T74286 2571-2580 NNS denotes cytokines
T39990 2581-2582 -LRB- denotes (
T86188 2582-2586 NN denotes IL-2
T98181 2586-2587 -COMMA- denotes ,
T95707 2588-2592 NN denotes IL-4
T51521 2592-2593 -COMMA- denotes ,
T13191 2594-2598 NN denotes IL-6
T97649 2598-2599 -COMMA- denotes ,
T67884 2600-2603 CC denotes and
T96461 2604-2609 NN denotes IL-10
T46182 2609-2610 -RRB- denotes )
T71095 2611-2614 CD denotes six
T75519 2615-2619 NNS denotes days
T70281 2620-2625 IN denotes after
T58821 2626-2635 NN denotes treatment
T68602 2637-2642 EX denotes There
T35641 2643-2645 VBZ denotes is
T96551 2646-2647 DT denotes a
T4246 2648-2654 NN denotes report
T68154 2655-2657 IN denotes of
T38317 2658-2661 DT denotes the
T15000 2662-2669 NN denotes patient
T78684 2670-2674 IN denotes with
T75392 2675-2683 NN denotes COVID-19
T66370 2684-2691 VBN denotes treated
T30686 2692-2696 IN denotes with
T52580 2697-2715 NN denotes methylprednisolone
T48202 2716-2721 IN denotes since
T9113 2722-2725 NN denotes day
T95658 2726-2727 CD denotes 8
T45554 2728-2730 IN denotes of
T3986 2731-2734 DT denotes the
T39007 2735-2742 NN denotes disease
T69348 2743-2749 NN denotes course
T97762 2751-2758 RB denotes However
T96472 2758-2759 -COMMA- denotes ,
T86008 2760-2763 PRP-DOLLAR- denotes his
T42849 2764-2773 NN denotes situation
T60930 2774-2782 VBD denotes worsened
T29454 2783-2786 CC denotes and
T36559 2787-2796 VBD denotes developed
T85992 2797-2808 JJ denotes respiratory
T55480 2809-2816 NN denotes failure
T13828 2817-2820 CC denotes and
T63285 2821-2825 VBD denotes died
T37916 2826-2828 IN denotes on
T9153 2829-2832 NN denotes day
T54332 2833-2835 CD denotes 14
T22231 2836-2837 -LRB- denotes [
T45405 2837-2839 CD denotes 32
T54531 2839-2840 -RRB- denotes ]
R70993 T36802 T24370 arg1Of Corticosteroids,7
R72739 T91345 T3294 arg1Of Hypothesis,7.1
R6776 T91345 T83198 arg1Of Hypothesis,:
R90351 T5476 T19383 arg1Of Corticosteroids,can
R4830 T18906 T19383 arg2Of modulate,can
R27738 T5476 T18906 arg1Of Corticosteroids,modulate
R34637 T94029 T18906 arg2Of inflammation,modulate
R14983 T27658 T8138 arg1Of Corticosteroids,are
R1800 T89187 T8138 arg2Of used,are
R30772 T89187 T91474 arg1Of used,commonly
R76656 T27658 T89187 arg2Of Corticosteroids,used
R83152 T89187 T38824 arg1Of used,for
R84216 T21445 T38824 arg2Of modulation,for
R71664 T21445 T58316 arg1Of modulation,of
R48317 T37655 T58316 arg2Of variety,of
R47267 T37655 T58021 arg1Of variety,a
R48435 T37655 T87627 arg1Of variety,of
R86835 T71073 T87627 arg2Of conditions,of
R39456 T71073 T8391 arg1Of conditions,inflammatory
R31135 T11971 T68994 arg1Of used,In
R76529 T59818 T68994 arg2Of addition,In
R33275 T59818 T18282 arg1Of addition,to
R34814 T35672 T18282 arg2Of regimen,to
R6389 T35672 T76082 arg1Of regimen,a
R46015 T35672 T38966 arg1Of regimen,daily
R96446 T11971 T41748 arg1Of used,","
R29876 T45789 T91069 arg1Of they,can
R96928 T11971 T91069 arg2Of used,can
R26417 T45789 T84858 arg1Of they,be
R27711 T11971 T84858 arg2Of used,be
R91907 T45789 T11971 arg2Of they,used
R53600 T90499 T11971 arg3Of treat,used
R25674 T11971 T91181 arg1Of used,in
R29015 T52866 T91181 arg2Of form,in
R85690 T52866 T55573 arg1Of form,the
R87967 T52866 T8605 arg1Of form,of
R68003 T43357 T8605 arg2Of therapy,of
R97154 T43357 T21111 arg1Of therapy,pulse
R38756 T90499 T46430 arg1Of treat,to
R5289 T45789 T90499 arg1Of they,treat
R88503 T36198 T90499 arg2Of flares,treat
R22941 T36198 T16735 arg1Of flares,of
R30207 T82392 T16735 arg2Of diseases,of
R64833 T82392 T37577 arg1Of diseases,autoimmune
R93978 T37602 T8787 arg1Of needed,However
R24390 T37602 T74715 arg1Of needed,","
R40383 T63832 T88619 arg1Of caution,in
R53932 T74757 T88619 arg2Of use,in
R49322 T74757 T72548 arg1Of use,the
R64073 T74757 T50691 arg1Of use,of
R93413 T75348 T50691 arg2Of corticosteroids,of
R94278 T63832 T98869 arg1Of caution,is
R11800 T37602 T98869 arg2Of needed,is
R49206 T32990 T98869 modOf suppress,is
R64524 T63832 T37602 arg2Of caution,needed
R49422 T37602 T93826 arg1Of needed,due
R37795 T93826 T27767 arg1Of due,to
R64331 T90339 T91545 arg1Of effects,the
R43912 T90339 T30802 arg1Of effects,potential
R95905 T90339 T82688 arg1Of effects,serious
R89670 T90339 T84923 arg1Of effects,side
R75209 T90339 T67748 arg2Of effects,associated
R82123 T67748 T22188 arg1Of associated,with
R97731 T1981 T22188 arg2Of and,with
R91222 T29681 T5158 arg1Of drugs,corticosteroid
R48726 T29681 T1981 arg1Of drugs,and
R3429 T73209 T1981 arg2Of corticosteroids,and
R78283 T73209 T7707 arg1Of corticosteroids,that
R39066 T32990 T32353 arg1Of suppress,generally
R41813 T90339 T32990 arg1Of effects,suppress
R62047 T82578 T32990 arg2Of system,suppress
R51061 T82578 T84727 arg1Of system,the
R76207 T82578 T72594 arg1Of system,immune
R86364 T73202 T98970 arg1Of latter,The
R26225 T73202 T49682 arg1Of latter,means
R25745 T40275 T49682 arg2Of ",",means
R20700 T40275 T56698 arg1Of ",",that
R35026 T44497 T44722 arg1Of corticosteroids,modulate
R76774 T14674 T44722 arg2Of inflammation,modulate
R24447 T14674 T39029 arg1Of inflammation,hyper
R58217 T44722 T31300 arg1Of modulate,and
R2013 T44722 T40275 arg1Of modulate,","
R80801 T14361 T40275 arg2Of inhibit,","
R44335 T14361 T84174 arg1Of inhibit,on
R96087 T79253 T84174 arg2Of hand,on
R31404 T79253 T84917 arg1Of hand,the
R34622 T79253 T41471 arg1Of hand,other
R33407 T14361 T80094 arg1Of inhibit,","
R60175 T44497 T14361 arg1Of corticosteroids,inhibit
R42871 T32652 T14361 arg2Of responses,inhibit
R3741 T32652 T92448 arg1Of responses,immune
R76507 T32652 T58197 arg1Of responses,that
R41346 T32652 T6432 arg1Of responses,are
R72901 T65734 T6432 arg2Of vital,are
R20900 T32652 T65734 arg1Of responses,vital
R42781 T65734 T7857 arg1Of vital,for
R62438 T39598 T7857 arg2Of defense,for
R39000 T39598 T27355 arg1Of defense,the
R37376 T39598 T81023 arg1Of defense,host
R88405 T39598 T97712 arg1Of defense,against
R90666 T59893 T97712 arg2Of virus,against
R66473 T59893 T6736 arg1Of virus,the
R9452 T14361 T48542 arg1Of inhibit,[
R81779 T9013 T48542 arg2Of 29,[
R24465 T33036 T48542 arg3Of ],[
R83938 T83170 T37227 arg1Of Rationale,7.2
R96084 T83170 T22490 arg1Of Rationale,:
R63665 T92502 T30425 arg1Of Corticosteroids,might
R55440 T17782 T30425 arg2Of help,might
R57612 T92502 T17782 arg1Of Corticosteroids,help
R96060 T8496 T17782 arg2Of accelerate,help
R33260 T92502 T8496 arg1Of Corticosteroids,accelerate
R88593 T16617 T8496 arg2Of recovery,accelerate
R45973 T16617 T39745 arg1Of recovery,from
R38722 T7154 T39745 arg2Of COVID-19,from
R65562 T20594 T19799 arg1Of study,The
R91543 T20594 T82079 arg1Of study,[
R68043 T66365 T82079 arg2Of 30,[
R8765 T51925 T82079 arg3Of ],[
R52690 T20594 T58773 arg1Of study,investigated
R62362 T17766 T58773 arg2Of effect,investigated
R80214 T17766 T62943 arg1Of effect,the
R30204 T17766 T91507 arg1Of effect,of
R57298 T59239 T91507 arg2Of and,of
R63916 T58635 T41721 arg2Of ",",inhaled
R43023 T58635 T68865 arg1Of ",",corticosteroids
R83908 T72129 T75975 arg1Of ciclesonide,","
R40147 T94153 T75975 arg2Of cortisone,","
R68981 T75975 T58635 arg1Of ",",","
R34809 T32129 T58635 arg2Of prednisolone,","
R35158 T58635 T52544 arg1Of ",",","
R94218 T7734 T52544 arg2Of dexamethasone,","
R66797 T59239 T48772 arg1Of and,","
R18975 T52544 T59239 arg1Of ",",and
R17941 T36302 T59239 arg2Of fluticasone,and
R76759 T36302 T2290 arg1Of fluticasone,on
R65488 T67274 T2290 arg2Of replication,on
R83692 T67274 T42645 arg1Of replication,the
R83433 T67274 T25492 arg1Of replication,of
R69453 T27491 T25492 arg2Of MERS-CoV,of
R5640 T27491 T52796 arg1Of MERS-CoV,the
R14892 T86672 T5267 arg1Of was,Among
R12867 T60636 T5267 arg2Of compounds,Among
R20551 T60636 T36393 arg1Of compounds,the
R45638 T60636 T1788 arg1Of compounds,four
R19889 T86672 T50162 arg1Of was,","
R6925 T45806 T78874 arg1Of ciclesonide,the
R51502 T45806 T22199 arg1Of ciclesonide,only
R80549 T45806 T86672 arg1Of ciclesonide,was
R88441 T12794 T86672 arg2Of capable,was
R54150 T45806 T12794 arg1Of ciclesonide,capable
R84902 T12794 T91797 arg1Of capable,of
R90818 T13593 T91797 arg2Of inhibiting,of
R59467 T45806 T13593 arg1Of ciclesonide,inhibiting
R61171 T7401 T13593 arg2Of replication,inhibiting
R62948 T7401 T5717 arg1Of replication,viral
R72412 T72578 T65340 arg1Of and,Also
R83353 T72578 T92623 arg1Of and,","
R13827 T81617 T95958 arg1Of ciclesonide,induced
R67632 T15429 T95958 arg2Of inhibition,induced
R52903 T15429 T85366 arg1Of inhibition,a
R95901 T15429 T21714 arg1Of inhibition,significant
R59832 T15429 T16699 arg1Of inhibition,of
R67342 T73696 T16699 arg2Of replication,of
R82929 T73696 T25584 arg1Of replication,viral
R28660 T73696 T7458 arg1Of replication,of
R31825 T40953 T7458 arg2Of coronaviruses,of
R98296 T40953 T20174 arg1Of coronaviruses,other
R36062 T40953 T58259 arg1Of coronaviruses,human
R24201 T40953 T84867 arg1Of coronaviruses,","
R18026 T19443 T83672 arg1Of as,such
R24587 T40953 T19443 arg1Of coronaviruses,as
R57525 T84685 T19443 arg2Of and,as
R99041 T95806 T84685 arg1Of HCoV-229E,and
R18584 T17277 T84685 arg2Of SARS-CoV,and
R60299 T72578 T94349 arg1Of and,","
R84710 T95958 T72578 arg1Of induced,and
R44966 T38146 T72578 arg2Of affect,and
R50591 T42602 T26171 arg1Of virus,another
R36647 T42602 T39629 arg1Of virus,positive-strand
R98576 T42602 T10581 arg1Of virus,RNA
R27749 T42602 T70474 arg1Of virus,","
R18576 T68058 T70474 arg2Of virus,","
R11915 T68058 T82553 arg1Of virus,rubella
R43356 T38146 T24019 arg1Of affect,","
R75887 T32300 T62462 arg1Of not,while
R44280 T38146 T32300 arg1Of affect,not
R91937 T42602 T38146 arg1Of virus,affect
R80466 T43382 T38146 arg2Of replication,affect
R95276 T43382 T72944 arg1Of replication,the
R61734 T43382 T97423 arg1Of replication,viral
R88271 T43382 T16861 arg1Of replication,of
R61511 T16801 T16861 arg2Of and,of
R90433 T51732 T53501 arg1Of viruses,negative-strand
R66191 T51732 T3387 arg1Of viruses,RNA
R5188 T51732 T35282 arg1Of viruses,","
R15638 T51732 T32607 arg1Of viruses,e.g.
R93190 T51732 T24756 arg1Of viruses,","
R92859 T29751 T24756 arg2Of influenza,","
R78785 T24756 T16801 arg1Of ",",and
R68118 T9582 T16801 arg2Of virus,and
R38873 T9582 T19789 arg1Of virus,respiratory
R7863 T9582 T17323 arg1Of virus,syncytial
R1995 T99202 T55931 arg1Of appeared,For
R6126 T92915 T55931 arg2Of MERS-CoV,For
R88085 T92915 T42084 arg1Of MERS-CoV,the
R79940 T99202 T45016 arg1Of appeared,","
R94118 T37738 T62094 arg1Of protein,a
R82408 T37738 T52727 arg1Of protein,nonstructural
R48240 T37738 T44869 arg1Of protein,15
R71223 T37738 T12678 arg1Of protein,(
R55825 T67952 T12678 arg2Of NSP15,(
R53099 T62960 T12678 arg3Of ),(
R16785 T37738 T99202 arg1Of protein,appeared
R13520 T75671 T99202 arg2Of act,appeared
R46727 T75671 T16450 arg1Of act,to
R20444 T37738 T75671 arg1Of protein,act
R15573 T75671 T10168 arg1Of act,as
R48367 T95644 T10168 arg2Of target,as
R90497 T95644 T75263 arg1Of target,the
R83237 T95644 T19735 arg1Of target,of
R92697 T45429 T19735 arg2Of ciclesonide,of
R20783 T13644 T28790 arg1Of substitution,An
R76164 T13644 T72966 arg1Of substitution,amino
R83793 T13644 T10430 arg1Of substitution,acid
R73378 T13644 T66951 arg1Of substitution,in
R18787 T82047 T66951 arg2Of NSP15,in
R39227 T82047 T16733 arg1Of NSP15,the
R65371 T13644 T5298 arg1Of substitution,conferred
R22776 T82196 T5298 arg2Of resistance,conferred
R90200 T82196 T91861 arg1Of resistance,of
R3544 T77495 T91861 arg2Of MERS-CoV,of
R34537 T77495 T16541 arg1Of MERS-CoV,the
R58093 T77495 T11735 arg2Of MERS-CoV,mutated
R53774 T82196 T54348 arg1Of resistance,to
R82049 T98167 T54348 arg2Of ciclesonide,to
R2236 T36698 T83057 arg1Of Mometasone,could
R84671 T32973 T83057 arg2Of help,could
R24093 T36698 T32973 arg1Of Mometasone,help
R32776 T81462 T32973 arg2Of deal,help
R18020 T36698 T81462 arg1Of Mometasone,deal
R11857 T81462 T7177 arg1Of deal,effectively
R16336 T81462 T91822 arg1Of deal,with
R70505 T94051 T91822 arg2Of MERS-CoV,with
R65523 T94051 T40647 arg1Of MERS-CoV,the
R9228 T94051 T69218 arg2Of MERS-CoV,mutated
R68878 T30995 T94597 arg1Of were,For
R91823 T49143 T94597 arg2Of SARS-CoV2,For
R46848 T49143 T52862 arg1Of SARS-CoV2,the
R23184 T30995 T76216 arg1Of were,","
R58043 T45337 T48579 arg1Of and,all
R7552 T54792 T87735 arg1Of ciclesonide,three
R28224 T54792 T41003 arg1Of ciclesonide,","
R78599 T64594 T41003 arg2Of mometasone,","
R82759 T45337 T89636 arg1Of and,","
R76678 T41003 T45337 arg1Of ",",and
R77720 T31426 T45337 arg2Of lopinavir,and
R11228 T45337 T30995 arg1Of and,were
R32948 T47275 T30995 arg2Of able,were
R73540 T45337 T47275 arg1Of and,able
R73449 T13737 T47275 arg2Of inhibit,able
R44161 T13737 T43506 arg1Of inhibit,to
R92204 T45337 T13737 arg1Of and,inhibit
R76291 T45532 T13737 arg2Of replication,inhibit
R30994 T45532 T48184 arg1Of replication,viral
R12341 T13737 T78456 arg1Of inhibit,to
R48043 T63329 T78456 arg2Of degree,to
R67825 T63329 T84667 arg1Of degree,a
R44939 T63329 T50127 arg1Of degree,similar
R15596 T26799 T13824 arg1Of was,Interestingly
R24705 T26799 T97722 arg1Of was,","
R73525 T29877 T32551 arg1Of effect,their
R81635 T29877 T26799 arg1Of effect,was
R5706 T71857 T26799 arg2Of noticeable,was
R45433 T71857 T38163 arg1Of noticeable,more
R94349 T29877 T71857 arg1Of effect,noticeable
R94809 T71857 T13399 arg1Of noticeable,than
R75113 T18879 T13399 arg2Of inhibitors,than
R31379 T18879 T61277 arg1Of inhibitors,serine
R89388 T18879 T95334 arg1Of inhibitors,protease
R12797 T18879 T2889 arg1Of inhibitors,","
R55160 T18879 T73448 arg1Of inhibitors,e.g.
R26094 T18879 T12218 arg1Of inhibitors,","
R31915 T84364 T12218 arg2Of and,","
R26263 T97193 T84364 arg1Of nafamostat,and
R85915 T56231 T84364 arg2Of camostat,and
R23540 T84364 T36295 arg1Of and,in
R7945 T50002 T36295 arg2Of cells,in
R37915 T50002 T41374 arg1Of cells,that
R79286 T50002 T64051 arg1Of cells,Vero
R22588 T69995 T64051 arg2Of cells,Vero
R48556 T69995 T3328 arg1Of cells,that
R51539 T69995 T80806 arg1Of cells,express
R51824 T14927 T80806 arg2Of TMPRSS2,express
R69829 T77594 T50088 arg1Of It,indicates
R64885 T11181 T50088 arg2Of tendency,indicates
R66606 T11181 T80437 arg1Of tendency,the
R72062 T11181 T22059 arg1Of tendency,of
R63884 T10513 T22059 arg2Of SARS-CoV2,of
R52625 T10513 T93173 arg1Of SARS-CoV2,the
R66017 T95799 T35356 arg1Of enter,to
R58532 T11181 T35356 modOf tendency,to
R56550 T81737 T95799 arg2Of cell,enter
R54662 T81737 T54387 arg1Of cell,the
R41067 T95799 T49362 arg1Of enter,through
R93053 T53710 T49362 arg2Of pathway,through
R36961 T53710 T16554 arg1Of pathway,the
R13940 T53710 T7152 arg1Of pathway,cathepsin/endosomal
R62122 T71892 T21481 arg1Of than,rather
R3351 T49362 T71892 arg1Of through,than
R57039 T13882 T71892 arg2Of through,than
R65615 T95799 T13882 arg1Of enter,through
R49728 T74893 T13882 arg2Of pathway,through
R87204 T74893 T1912 arg1Of pathway,the
R67917 T74893 T96928 arg1Of pathway,TMPRSS2/cell
R10707 T74893 T71956 arg1Of pathway,surface
R64586 T65117 T35160 arg1Of study,The
R22489 T65117 T45353 arg1Of study,[
R5694 T58501 T45353 arg2Of 31,[
R4977 T88016 T45353 arg3Of ],[
R7566 T65117 T88407 arg1Of study,included
R20385 T33446 T88407 arg2Of patients,included
R30779 T33446 T16300 arg1Of patients,46
R95770 T33446 T87886 arg1Of patients,with
R97198 T97970 T87886 arg2Of COVID-19,with
R49171 T97970 T58994 arg1Of COVID-19,severe
R35699 T88407 T41758 arg1Of included,","
R93763 T76496 T41758 arg2Of received,","
R16819 T76496 T58135 arg1Of received,of
R87137 T73561 T58135 arg2Of patients,of
R12315 T73561 T85647 arg1Of patients,these
R90367 T73561 T95602 arg1Of patients,26
R81582 T65117 T76496 arg1Of study,received
R44629 T42976 T76496 arg2Of methylprednisolone,received
R76194 T42976 T32544 arg1Of methylprednisolone,(
R40262 T60914 T32544 arg2Of 1–2 mg/kg/d,(
R66581 T28841 T32544 arg3Of ),(
R38992 T60914 T95632 arg1Of 1–2 mg/kg/d,for
R85093 T23094 T95632 arg2Of 5–7 days,for
R65720 T5759 T83750 arg1Of and,","
R2337 T41758 T5759 arg1Of ",",and
R8712 T96732 T5759 arg2Of received,and
R65190 T13615 T23681 arg1Of patients,20
R50258 T13615 T96732 arg1Of patients,received
R24762 T84414 T96732 arg2Of therapy,received
R75895 T84414 T97501 arg1Of therapy,standard
R18127 T84414 T2990 arg1Of therapy,without
R85994 T83484 T2990 arg2Of methylprednisolone,without
R52418 T58218 T55303 arg1Of group,The
R25309 T58218 T42547 arg1Of group,first
R81725 T58218 T37085 arg1Of group,achieved
R2693 T54798 T37085 arg2Of improvement,achieved
R24035 T54798 T74264 arg1Of improvement,faster
R63842 T54798 T77136 arg1Of improvement,in
R3939 T34896 T77136 arg2Of and,in
R44421 T98040 T46765 arg1Of symptoms,clinical
R37097 T98040 T23999 arg1Of symptoms,(
R73275 T65661 T23999 arg2Of and,(
R12543 T5300 T23999 arg3Of ),(
R15972 T37402 T65661 arg1Of fever,and
R68332 T9527 T65661 arg2Of saturation,and
R47680 T9527 T89758 arg1Of saturation,peripheral
R77580 T9527 T63703 arg1Of saturation,oxygen
R11535 T98040 T34896 arg1Of symptoms,and
R78424 T64673 T34896 arg2Of lesions,and
R25227 T64673 T9982 arg1Of lesions,lung
R8733 T8195 T90980 arg1Of imaging,detected
R3999 T64673 T90980 arg2Of lesions,detected
R58092 T8195 T16483 arg2Of imaging,by
R70763 T8195 T31403 arg1Of imaging,CT
R73246 T32769 T7710 arg1Of occurred,However
R42977 T32769 T57863 arg1Of occurred,","
R90696 T43356 T19219 arg1Of deaths,two
R78087 T43356 T32769 arg1Of deaths,occurred
R2074 T32769 T5412 arg1Of occurred,in
R67856 T72564 T5412 arg2Of and,in
R76205 T72564 T52171 arg1Of and,the
R59428 T18985 T5683 arg1Of group,first
R19610 T18985 T72564 arg1Of group,and
R73808 T21460 T72564 arg2Of death,and
R60151 T21460 T66890 arg1Of death,one
R56134 T32769 T49866 arg1Of occurred,in
R23329 T89439 T49866 arg2Of group,in
R47378 T89439 T26278 arg1Of group,the
R61252 T89439 T96270 arg1Of group,second
R68253 T18576 T61059 arg1Of differ,Moreover
R81037 T18576 T97295 arg1Of differ,","
R53458 T39437 T66784 arg1Of groups,the
R16309 T39437 T32526 arg1Of groups,two
R69157 T39437 T87016 arg1Of groups,did
R72743 T18576 T87016 arg2Of differ,did
R76339 T18576 T42838 arg1Of differ,not
R11494 T39437 T18576 arg1Of groups,differ
R38432 T18576 T50188 arg1Of differ,in
R3470 T16685 T50188 arg2Of parameters,in
R53455 T16685 T80686 arg1Of parameters,laboratory
R90661 T16685 T92910 arg1Of parameters,","
R19525 T16685 T79314 arg1Of parameters,including
R44574 T39782 T79314 arg2Of and,including
R16864 T58552 T52445 arg1Of WBC,","
R81496 T50601 T52445 arg2Of count,","
R72933 T50601 T19300 arg1Of count,lymphocyte
R4945 T52445 T15065 arg1Of ",",","
R51680 T31332 T15065 arg2Of count,","
R51130 T31332 T27527 arg1Of count,monocyte
R69030 T39782 T62470 arg1Of and,","
R12232 T15065 T39782 arg1Of ",",and
R44220 T74286 T39782 arg2Of cytokines,and
R54057 T74286 T39990 arg1Of cytokines,(
R67482 T67884 T39990 arg2Of and,(
R81532 T46182 T39990 arg3Of ),(
R6337 T86188 T98181 arg1Of IL-2,","
R78024 T95707 T98181 arg2Of IL-4,","
R89055 T98181 T51521 arg1Of ",",","
R12235 T13191 T51521 arg2Of IL-6,","
R48546 T67884 T97649 arg1Of and,","
R72360 T51521 T67884 arg1Of ",",and
R15075 T96461 T67884 arg2Of IL-10,and
R98942 T75519 T71095 arg1Of days,six
R22355 T70281 T75519 arg1Of after,days
R66219 T39782 T70281 arg1Of and,after
R53333 T58821 T70281 arg2Of treatment,after
R82494 T68602 T35641 arg1Of There,is
R73815 T4246 T35641 arg2Of report,is
R5528 T4246 T96551 arg1Of report,a
R12784 T4246 T68154 arg1Of report,of
R58615 T15000 T68154 arg2Of patient,of
R70338 T15000 T38317 arg1Of patient,the
R29523 T15000 T78684 arg1Of patient,with
R89677 T75392 T78684 arg2Of COVID-19,with
R64105 T75392 T66370 arg2Of COVID-19,treated
R49772 T66370 T30686 arg1Of treated,with
R57077 T52580 T30686 arg2Of methylprednisolone,with
R18015 T52580 T48202 arg1Of methylprednisolone,since
R60177 T9113 T48202 arg2Of day,since
R56648 T9113 T95658 arg1Of day,8
R72223 T9113 T45554 arg1Of day,of
R63506 T69348 T45554 arg2Of course,of
R4360 T69348 T3986 arg1Of course,the
R29456 T69348 T39007 arg1Of course,disease
R67593 T13828 T97762 arg1Of and,However
R45567 T13828 T96472 arg1Of and,","
R98500 T42849 T86008 arg1Of situation,his
R42021 T42849 T60930 arg1Of situation,worsened
R48458 T60930 T29454 arg1Of worsened,and
R24659 T36559 T29454 arg2Of developed,and
R94493 T42849 T36559 arg1Of situation,developed
R76701 T55480 T36559 arg2Of failure,developed
R53204 T55480 T85992 arg1Of failure,respiratory
R27664 T29454 T13828 arg1Of and,and
R87462 T63285 T13828 arg2Of died,and
R91325 T42849 T63285 arg1Of situation,died
R11819 T63285 T37916 arg1Of died,on
R13996 T9153 T37916 arg2Of day,on
R44977 T9153 T54332 arg1Of day,14
R52673 T9153 T22231 arg1Of day,[
R93142 T45405 T22231 arg2Of 32,[
R43374 T54531 T22231 arg3Of ],[

LitCovid-sample-PD-MAT

Id Subject Object Predicate Lexical cue
T8 570-574 http://purl.obolibrary.org/obo/MAT_0000091 denotes hand
T9 2332-2336 http://purl.obolibrary.org/obo/MAT_0000135 denotes lung

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T33 66-78 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T34 539-551 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T35 576-600 http://purl.obolibrary.org/obo/GO_0050777 denotes inhibit immune responses
T36 584-600 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T37 972-1000 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibiting viral replication
T38 983-1000 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T39 983-1000 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T40 1042-1073 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibition of viral replication
T41 1056-1073 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T42 1056-1073 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T43 1211-1228 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T44 1211-1228 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T45 1657-1682 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibit viral replication
T46 1665-1682 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T47 1665-1682 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T48 2425-2430 http://purl.obolibrary.org/obo/GO_0016265 denotes death

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T167 471-484 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T168 570-574 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T169 1164-1167 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T170 1248-1251 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T171 1344-1351 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T172 1412-1422 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T173 1757-1763 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T174 1818-1823 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T175 1834-1839 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T176 1918-1922 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T177 1945-1954 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T178 1995-2007 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T179 1995-1999 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T180 2332-2336 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T181 2533-2543 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T182 2551-2559 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T183 2571-2580 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T184 2582-2586 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T171 66-78 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T172 266-285 Disease denotes autoimmune diseases http://purl.obolibrary.org/obo/MONDO_0007179
T173 539-551 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T174 730-738 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T175 1126-1134 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T176 1175-1182 Disease denotes rubella http://purl.obolibrary.org/obo/MONDO_0004656
T177 1267-1276 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T178 1584-1593 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T179 1895-1904 Disease denotes SARS-CoV2 http://purl.obolibrary.org/obo/MONDO_0100096
T180 2065-2073 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T181 2675-2683 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T182 2797-2816 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113

LitCovid-sample-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T14 266-285 Phenotype denotes autoimmune diseases http://purl.obolibrary.org/obo/HP_0002960
T15 2288-2293 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T16 2797-2816 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T29 66-78 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T30 539-551 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T31 576-600 http://purl.obolibrary.org/obo/GO_0050777 denotes inhibit immune responses
T32 584-600 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T33 972-1000 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibiting viral replication
T34 983-1000 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T35 983-1000 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T36 1042-1073 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibition of viral replication
T37 1056-1073 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T38 1056-1073 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T39 1211-1228 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T40 1211-1228 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T41 1657-1682 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibit viral replication
T42 1665-1682 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T43 1665-1682 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T29 66-78 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T30 539-551 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T31 576-600 http://purl.obolibrary.org/obo/GO_0050777 denotes inhibit immune responses
T32 584-600 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T33 972-1000 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibiting viral replication
T34 983-1000 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T35 983-1000 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T36 1042-1073 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibition of viral replication
T37 1056-1073 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T38 1056-1073 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T39 1211-1228 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T40 1211-1228 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T41 1657-1682 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibit viral replication
T42 1665-1682 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T43 1665-1682 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T189 0-18 Sentence denotes 7 Corticosteroids
T190 20-36 Sentence denotes 7.1 Hypothesis:
T191 37-78 Sentence denotes Corticosteroids can modulate inflammation
T192 79-168 Sentence denotes Corticosteroids are commonly used for modulation of a variety of inflammatory conditions.
T193 169-286 Sentence denotes In addition to a daily regimen, they can be used in the form of pulse therapy to treat flares of autoimmune diseases.
T194 287-485 Sentence denotes However, caution in the use of corticosteroids is needed due to the potential serious side effects associated with corticosteroid drugs and that corticosteroids generally suppress the immune system.
T195 486-660 Sentence denotes The latter means that corticosteroids modulate hyper inflammation and, on the other hand, inhibit immune responses that are vital for the host defense against the virus [29].
T196 662-677 Sentence denotes 7.2 Rationale:
T197 678-738 Sentence denotes Corticosteroids might help accelerate recovery from COVID-19
T198 739-909 Sentence denotes The study [30] investigated the effect of inhaled corticosteroids ciclesonide, cortisone, prednisolone, dexamethasone, and fluticasone on the replication of the MERS-CoV.
T199 910-1001 Sentence denotes Among the four compounds, the only ciclesonide was capable of inhibiting viral replication.
T200 1002-1309 Sentence denotes Also, ciclesonide induced a significant inhibition of viral replication of other human coronaviruses, such as HCoV-229E and SARS-CoV, and another positive-strand RNA virus, rubella virus, while not affect the viral replication of negative-strand RNA viruses, e.g., influenza and respiratory syncytial virus.
T201 1310-1408 Sentence denotes For the MERS-CoV, a nonstructural protein 15 (NSP15) appeared to act as the target of ciclesonide.
T202 1409-1509 Sentence denotes An amino acid substitution in the NSP15 conferred resistance of the mutated MERS-CoV to ciclesonide.
T203 1510-1575 Sentence denotes Mometasone could help deal effectively with the mutated MERS-CoV.
T204 1576-1703 Sentence denotes For the SARS-CoV2, all three ciclesonide, mometasone, and lopinavir were able to inhibit viral replication to a similar degree.
T205 1704-1861 Sentence denotes Interestingly, their effect was more noticeable than serine protease inhibitors, e.g., nafamostat and camostat in cells that Vero cells that express TMPRSS2.
T206 1862-2016 Sentence denotes It indicates the tendency of the SARS-CoV2 to enter the cell through the cathepsin/endosomal pathway rather than through the TMPRSS2/cell surface pathway.
T207 2017-2221 Sentence denotes The study [31] included 46 patients with severe COVID-19, of these 26 patients received methylprednisolone (1–2 mg/kg/d for 5–7 days), and 20 patients received standard therapy without methylprednisolone.
T208 2222-2368 Sentence denotes The first group achieved faster improvement in clinical symptoms (fever and peripheral oxygen saturation) and lung lesions detected by CT imaging.
T209 2369-2451 Sentence denotes However, two deaths occurred in the first group and one death in the second group.
T210 2452-2636 Sentence denotes Moreover, the two groups did not differ in laboratory parameters, including WBC, lymphocyte count, monocyte count, and cytokines (IL-2, IL-4, IL-6, and IL-10) six days after treatment.
T211 2637-2750 Sentence denotes There is a report of the patient with COVID-19 treated with methylprednisolone since day 8 of the disease course.
T212 2751-2841 Sentence denotes However, his situation worsened and developed respiratory failure and died on day 14 [32].

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T15 266-285 Phenotype denotes autoimmune diseases http://purl.obolibrary.org/obo/HP_0002960
T16 2288-2293 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T17 2797-2816 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878