
PMC:7205724 / 21921-22331
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
760 | 374-382 | Species | denotes | children | Tax:9606 |
761 | 58-63 | Species | denotes | human | Tax:9606 |
762 | 0-11 | Chemical | denotes | Tocilizumab | MESH:C502936 |
763 | 131-150 | Disease | denotes | autoimmune diseases | MESH:D001327 |
764 | 194-214 | Disease | denotes | rheumatoid arthritis | MESH:D001172 |
765 | 216-236 | Disease | denotes | giant cell arteritis | MESH:D013700 |
766 | 238-281 | Disease | denotes | polyarticular juvenile idiopathic arthritis | MESH:D001171 |
767 | 287-327 | Disease | denotes | systematic juvenile idiopathic arthritis | MESH:D001171 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T160 | 77-85 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T161 | 167-175 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T162 | 222-226 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T165 | 131-150 | Disease | denotes | autoimmune diseases | http://purl.obolibrary.org/obo/MONDO_0007179 |
T166 | 194-214 | Disease | denotes | rheumatoid arthritis | http://purl.obolibrary.org/obo/MONDO_0008383 |
T167 | 205-214 | Disease | denotes | arthritis | http://purl.obolibrary.org/obo/MONDO_0005578 |
T168 | 216-236 | Disease | denotes | giant cell arteritis | http://purl.obolibrary.org/obo/MONDO_0008538 |
T169 | 227-236 | Disease | denotes | arteritis | http://purl.obolibrary.org/obo/MONDO_0043494 |
T170 | 238-281 | Disease | denotes | polyarticular juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/MONDO_0018456 |
T171 | 252-281 | Disease | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/MONDO_0011429 |
T172 | 272-281 | Disease | denotes | arthritis | http://purl.obolibrary.org/obo/MONDO_0005578 |
T173 | 298-327 | Disease | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/MONDO_0011429 |
T174 | 318-327 | Disease | denotes | arthritis | http://purl.obolibrary.org/obo/MONDO_0005578 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T261 | 41-42 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T262 | 43-52 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humanized |
T263 | 58-63 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T264 | 222-226 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T100 | 142-150 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | diseases |
T101 | 222-226 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T216 | 58-63 | Species | denotes | human | NCBItxid:9606 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T179 | 0-328 | Sentence | denotes | Tocilizumab, also known as atlizumab, is a humanized anti-human IL6 receptor antibody approved by FDA for several inflammatory and autoimmune diseases severe, such as cytokine release syndrome, rheumatoid arthritis, giant cell arteritis, polyarticular juvenile idiopathic arthritis, and systematic juvenile idiopathic arthritis. |
T180 | 329-410 | Sentence | denotes | It is safe and effective for both adults and children two years of age and older. |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
762 | 0-11 | Chemical | denotes | Tocilizumab | MESH:C502936 |
761 | 58-63 | Species | denotes | human | Tax:9606 |
763 | 131-150 | Disease | denotes | autoimmune diseases | MESH:D001327 |
764 | 194-214 | Disease | denotes | rheumatoid arthritis | MESH:D001172 |
765 | 216-236 | Disease | denotes | giant cell arteritis | MESH:D013700 |
766 | 238-281 | Disease | denotes | polyarticular juvenile idiopathic arthritis | MESH:D001171 |
767 | 287-327 | Disease | denotes | systematic juvenile idiopathic arthritis | MESH:D001171 |
760 | 374-382 | Species | denotes | children | Tax:9606 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T2117 | 64-67 | Protein | denotes | IL6 | https://www.uniprot.org/uniprot/Q9XT80|https://www.uniprot.org/uniprot/Q9UCU4|https://www.uniprot.org/uniprot/Q9UCU3|https://www.uniprot.org/uniprot/Q9UCU2|https://www.uniprot.org/uniprot/Q9MZR1|https://www.uniprot.org/uniprot/Q9MYZ7|https://www.uniprot.org/uniprot/Q95KN6|https://www.uniprot.org/uniprot/Q95181|https://www.uniprot.org/uniprot/Q90YI0|https://www.uniprot.org/uniprot/Q8MKH0|https://www.uniprot.org/uniprot/Q8BN26|https://www.uniprot.org/uniprot/Q865X6|https://www.uniprot.org/uniprot/Q865W7|https://www.uniprot.org/uniprot/Q6V919|https://www.uniprot.org/uniprot/Q6L6X6|https://www.uniprot.org/uniprot/Q5I6E3|https://www.uniprot.org/uniprot/Q3UCQ0|https://www.uniprot.org/uniprot/Q2MH06|https://www.uniprot.org/uniprot/Q28819|https://www.uniprot.org/uniprot/Q28747|https://www.uniprot.org/uniprot/Q28319|https://www.uniprot.org/uniprot/Q25BC2|https://www.uniprot.org/uniprot/Q0PW36|https://www.uniprot.org/uniprot/Q0GGL7|https://www.uniprot.org/uniprot/Q08DT2|https://www.uniprot.org/uniprot/P79341|https://www.uniprot.org/uniprot/P51494|https://www.uniprot.org/uniprot/P46650|https://www.uniprot.org/uniprot/P41693|https://www.uniprot.org/uniprot/P41683|https://www.uniprot.org/uniprot/P41323|https://www.uniprot.org/uniprot/P29455|https://www.uniprot.org/uniprot/P26893|https://www.uniprot.org/uniprot/P26892|https://www.uniprot.org/uniprot/P20607|https://www.uniprot.org/uniprot/P08505|https://www.uniprot.org/uniprot/P05231|https://www.uniprot.org/uniprot/O46568|https://www.uniprot.org/uniprot/O35736|https://www.uniprot.org/uniprot/O19007|https://www.uniprot.org/uniprot/B6CKP4|https://www.uniprot.org/uniprot/A9QWQ9|https://www.uniprot.org/uniprot/A3FBE9|https://www.uniprot.org/uniprot/A0S0B0 |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T86439 | 0-11 | NNP | denotes | Tocilizumab |
T21494 | 11-12 | -COMMA- | denotes | , |
T50157 | 13-17 | RB | denotes | also |
T26283 | 18-23 | VBN | denotes | known |
T43571 | 24-26 | IN | denotes | as |
T44785 | 27-36 | NN | denotes | atlizumab |
T96810 | 36-37 | -COMMA- | denotes | , |
T58761 | 38-40 | VBZ | denotes | is |
T56416 | 41-42 | DT | denotes | a |
T79548 | 43-52 | JJ | denotes | humanized |
T29074 | 53-63 | JJ | denotes | anti-human |
T88685 | 64-67 | NN | denotes | IL6 |
T26777 | 68-76 | NN | denotes | receptor |
T24185 | 77-85 | NN | denotes | antibody |
T17221 | 86-94 | VBN | denotes | approved |
T32471 | 95-97 | IN | denotes | by |
T53882 | 98-101 | NNP | denotes | FDA |
T24580 | 102-105 | IN | denotes | for |
T33924 | 106-113 | JJ | denotes | several |
T90119 | 114-126 | JJ | denotes | inflammatory |
T59846 | 127-130 | CC | denotes | and |
T31666 | 131-141 | JJ | denotes | autoimmune |
T46803 | 142-150 | NNS | denotes | diseases |
T80969 | 151-157 | JJ | denotes | severe |
T13017 | 157-158 | -COMMA- | denotes | , |
T79015 | 159-163 | JJ | denotes | such |
T43255 | 164-166 | IN | denotes | as |
T47553 | 167-175 | NN | denotes | cytokine |
T34694 | 176-183 | NN | denotes | release |
T36705 | 184-192 | NN | denotes | syndrome |
T68837 | 192-193 | -COMMA- | denotes | , |
T30269 | 194-204 | JJ | denotes | rheumatoid |
T54700 | 205-214 | NN | denotes | arthritis |
T81658 | 214-215 | -COMMA- | denotes | , |
T84650 | 216-221 | JJ | denotes | giant |
T11095 | 222-226 | NN | denotes | cell |
T15987 | 227-236 | NN | denotes | arteritis |
T88887 | 236-237 | -COMMA- | denotes | , |
T31599 | 238-251 | JJ | denotes | polyarticular |
T93322 | 252-260 | JJ | denotes | juvenile |
T49595 | 261-271 | JJ | denotes | idiopathic |
T62141 | 272-281 | NN | denotes | arthritis |
T76737 | 281-282 | -COMMA- | denotes | , |
T30470 | 283-286 | CC | denotes | and |
T13999 | 287-297 | JJ | denotes | systematic |
T88238 | 298-306 | JJ | denotes | juvenile |
T89892 | 307-317 | JJ | denotes | idiopathic |
T97598 | 318-327 | NN | denotes | arthritis |
T25454 | 329-331 | PRP | denotes | It |
T28665 | 332-334 | VBZ | denotes | is |
T15312 | 335-339 | JJ | denotes | safe |
T18121 | 340-343 | CC | denotes | and |
T2467 | 344-353 | JJ | denotes | effective |
T39207 | 354-357 | IN | denotes | for |
T89869 | 358-362 | DT | denotes | both |
T32842 | 363-369 | NNS | denotes | adults |
T38357 | 370-373 | CC | denotes | and |
T13891 | 374-382 | NNS | denotes | children |
T61388 | 383-386 | CD | denotes | two |
T66576 | 387-392 | NNS | denotes | years |
T46590 | 393-395 | IN | denotes | of |
T15404 | 396-399 | NN | denotes | age |
T19164 | 400-403 | CC | denotes | and |
T99851 | 404-409 | JJR | denotes | older |
R83125 | T86439 | T21494 | arg1Of | Tocilizumab,"," |
R13146 | T26283 | T50157 | arg1Of | known,also |
R82868 | T86439 | T26283 | arg2Of | Tocilizumab,known |
R76811 | T26283 | T43571 | arg1Of | known,as |
R6462 | T44785 | T43571 | arg2Of | atlizumab,as |
R65301 | T58761 | T96810 | arg1Of | is,"," |
R91756 | T86439 | T58761 | arg1Of | Tocilizumab,is |
R48338 | T24185 | T58761 | arg2Of | antibody,is |
R19276 | T24185 | T56416 | arg1Of | antibody,a |
R24087 | T24185 | T79548 | arg1Of | antibody,humanized |
R65895 | T24185 | T29074 | arg1Of | antibody,anti-human |
R2263 | T24185 | T88685 | arg1Of | antibody,IL6 |
R21524 | T24185 | T26777 | arg1Of | antibody,receptor |
R18021 | T53882 | T17221 | arg1Of | FDA,approved |
R77534 | T24185 | T17221 | arg2Of | antibody,approved |
R58214 | T53882 | T32471 | arg2Of | FDA,by |
R27887 | T17221 | T24580 | arg1Of | approved,for |
R20734 | T80969 | T24580 | arg2Of | severe,for |
R13465 | T46803 | T33924 | arg1Of | diseases,several |
R86212 | T46803 | T90119 | arg1Of | diseases,inflammatory |
R60939 | T90119 | T59846 | arg1Of | inflammatory,and |
R4444 | T31666 | T59846 | arg2Of | autoimmune,and |
R87485 | T46803 | T31666 | arg1Of | diseases,autoimmune |
R90538 | T46803 | T80969 | arg1Of | diseases,severe |
R97819 | T17221 | T13017 | arg1Of | approved,"," |
R24341 | T43255 | T79015 | arg1Of | as,such |
R92610 | T24185 | T43255 | arg1Of | antibody,as |
R33248 | T30470 | T43255 | arg2Of | and,as |
R45357 | T36705 | T47553 | arg1Of | syndrome,cytokine |
R21959 | T36705 | T34694 | arg1Of | syndrome,release |
R41949 | T36705 | T68837 | arg1Of | syndrome,"," |
R19260 | T54700 | T68837 | arg2Of | arthritis,"," |
R59437 | T54700 | T30269 | arg1Of | arthritis,rheumatoid |
R79844 | T68837 | T81658 | arg1Of | ",","," |
R96846 | T15987 | T81658 | arg2Of | arteritis,"," |
R42046 | T15987 | T84650 | arg1Of | arteritis,giant |
R12475 | T15987 | T11095 | arg1Of | arteritis,cell |
R20864 | T81658 | T88887 | arg1Of | ",","," |
R12170 | T62141 | T88887 | arg2Of | arthritis,"," |
R2759 | T62141 | T31599 | arg1Of | arthritis,polyarticular |
R56313 | T62141 | T93322 | arg1Of | arthritis,juvenile |
R57671 | T62141 | T49595 | arg1Of | arthritis,idiopathic |
R19638 | T30470 | T76737 | arg1Of | and,"," |
R50655 | T88887 | T30470 | arg1Of | ",",and |
R47508 | T97598 | T30470 | arg2Of | arthritis,and |
R2665 | T97598 | T13999 | arg1Of | arthritis,systematic |
R42821 | T97598 | T88238 | arg1Of | arthritis,juvenile |
R23852 | T97598 | T89892 | arg1Of | arthritis,idiopathic |
R65763 | T25454 | T28665 | arg1Of | It,is |
R63345 | T18121 | T28665 | arg2Of | and,is |
R33385 | T25454 | T15312 | arg1Of | It,safe |
R71645 | T15312 | T18121 | arg1Of | safe,and |
R79824 | T2467 | T18121 | arg2Of | effective,and |
R87665 | T25454 | T2467 | arg1Of | It,effective |
R86934 | T18121 | T39207 | arg1Of | and,for |
R81304 | T38357 | T39207 | arg2Of | and,for |
R77360 | T38357 | T89869 | arg1Of | and,both |
R78333 | T32842 | T38357 | arg1Of | adults,and |
R34196 | T13891 | T38357 | arg2Of | children,and |
R37501 | T66576 | T61388 | arg1Of | years,two |
R85448 | T38357 | T66576 | arg1Of | and,years |
R80686 | T66576 | T46590 | arg1Of | years,of |
R92175 | T15404 | T46590 | arg2Of | age,of |
R77190 | T66576 | T19164 | arg1Of | years,and |
R33791 | T99851 | T19164 | arg2Of | older,and |
R24950 | T38357 | T99851 | arg1Of | and,older |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T160 | 77-85 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T161 | 167-175 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
T162 | 222-226 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T160 | 131-150 | Disease | denotes | autoimmune diseases | http://purl.obolibrary.org/obo/MONDO_0007179 |
T161 | 194-214 | Disease | denotes | rheumatoid arthritis | http://purl.obolibrary.org/obo/MONDO_0008383 |
T162 | 216-236 | Disease | denotes | giant cell arteritis | http://purl.obolibrary.org/obo/MONDO_0008538 |
T163 | 238-281 | Disease | denotes | polyarticular juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/MONDO_0018456 |
T164 | 298-327 | Disease | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/MONDO_0011429 |
LitCovid-sample-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T9 | 131-150 | Phenotype | denotes | autoimmune diseases | http://purl.obolibrary.org/obo/HP_0002960 |
T10 | 194-214 | Phenotype | denotes | rheumatoid arthritis | http://purl.obolibrary.org/obo/HP_0001370 |
T11 | 227-236 | Phenotype | denotes | arteritis | http://purl.obolibrary.org/obo/HP_0012089 |
T12 | 252-281 | Phenotype | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/HP_0005681 |
T13 | 298-327 | Phenotype | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/HP_0005681 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T179 | 0-328 | Sentence | denotes | Tocilizumab, also known as atlizumab, is a humanized anti-human IL6 receptor antibody approved by FDA for several inflammatory and autoimmune diseases severe, such as cytokine release syndrome, rheumatoid arthritis, giant cell arteritis, polyarticular juvenile idiopathic arthritis, and systematic juvenile idiopathic arthritis. |
T180 | 329-410 | Sentence | denotes | It is safe and effective for both adults and children two years of age and older. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T9 | 131-150 | Phenotype | denotes | autoimmune diseases | http://purl.obolibrary.org/obo/HP_0002960 |
T10 | 167-192 | Phenotype | denotes | cytokine release syndrome | http://purl.obolibrary.org/obo/HP_0033041 |
T11 | 194-214 | Phenotype | denotes | rheumatoid arthritis | http://purl.obolibrary.org/obo/HP_0001370 |
T12 | 227-236 | Phenotype | denotes | arteritis | http://purl.obolibrary.org/obo/HP_0012089 |
T13 | 252-281 | Phenotype | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/HP_0005681 |
T14 | 298-327 | Phenotype | denotes | juvenile idiopathic arthritis | http://purl.obolibrary.org/obo/HP_0005681 |