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PMC:7205724 / 20660-21300 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
713 638-639 Gene denotes S Gene:43740568
714 625-626 Gene denotes S Gene:43740568
715 482-483 Gene denotes S Gene:43740568
716 423-424 Gene denotes S Gene:43740568
717 411-412 Gene denotes S Gene:43740568
718 279-280 Gene denotes S Gene:43740568
719 80-95 Species denotes transgenic mice Tax:10090
720 113-118 Species denotes human Tax:9606
721 161-164 Species denotes rat Tax:10116
722 272-278 Species denotes SARS-2 Tax:2697049
723 417-422 Species denotes SARS2 Tax:2697049
724 476-481 Species denotes SARS2 Tax:2697049
725 631-637 Species denotes SARS-2 Tax:2697049
726 366-384 Disease denotes decreased syncytia MESH:D002303
727 444-450 CellLine denotes VeroE6 CVCL:0574

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T151 44-52 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T152 119-133 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T153 172-186 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T154 311-319 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T155 451-456 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T153 261-265 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T154 272-276 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T155 406-410 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T156 465-469 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T157 620-624 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T158 631-635 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T242 10-19 http://purl.obolibrary.org/obo/CLO_0036932 denotes hybridoma
T243 113-118 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T244 335-336 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T245 356-364 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T246 444-456 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T247 496-501 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T248 589-591 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1

LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T19 119-133 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes immunoglobulin http://purl.bioontology.org/ontology/MEDDRA/10021496
T20 172-186 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes immunoglobulin http://purl.bioontology.org/ontology/MEDDRA/10021496

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T97 451-456 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T98 496-501 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T197 91-95 Species denotes mice NCBItxid:10095|NCBItxid:10088
T199 113-118 Species denotes human NCBItxid:9606
T200 161-164 Species denotes rat NCBItxid:10116|NCBItxid:10114
T202 261-265 Species denotes SARS NCBItxid:694009
T203 272-278 Species denotes SARS-2 NCBItxid:2697049
T204 406-410 Species denotes SARS NCBItxid:694009
T205 417-422 Species denotes SARS2 NCBItxid:2697049
T206 465-469 Species denotes SARS NCBItxid:694009
T207 476-481 Species denotes SARS2 NCBItxid:2697049
T208 620-624 Species denotes SARS NCBItxid:694009
T209 631-637 Species denotes SARS-2 NCBItxid:2697049

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T168 0-286 Sentence denotes Recently, hybridoma supernatants containing antibody repertoires from immunized transgenic mice that express the human immunoglobulin heavy and light chains and rat origin immunoglobulin constant regions were used to detect antibodies that can cross neutralize SARS-S and SARS-2-S [26].
T169 287-507 Sentence denotes One chimeric 47D11 H2L2 antibody displayed such a cross-neutralizing activity, decreased syncytia formation induced by SARS-S and SARS2-S, and could protect VeroE6 cells against SARS-S and SARS2-S pseudotyped virus [26].
T170 508-640 Sentence denotes It may lie in its similar affinities for interacting with the same domain of the S1 subunit, i.e., S1B, of each SARS-S and SARS-2-S.

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
719 80-95 Species denotes transgenic mice Tax:10090
720 113-118 Species denotes human Tax:9606
721 161-164 Species denotes rat Tax:10116
722 272-278 Species denotes SARS-2 Tax:2697049
718 279-280 Gene denotes S Gene:43740568
726 366-384 Disease denotes decreased syncytia MESH:D002303
717 411-412 Gene denotes S Gene:43740568
723 417-422 Species denotes SARS2 Tax:2697049
716 423-424 Gene denotes S Gene:43740568
727 444-450 CellLine denotes VeroE6 CVCL:0574
724 476-481 Species denotes SARS2 Tax:2697049
715 482-483 Gene denotes S Gene:43740568
714 625-626 Gene denotes S Gene:43740568
725 631-637 Species denotes SARS-2 Tax:2697049
713 638-639 Gene denotes S Gene:43740568

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T2069 607-610 Protein denotes S1B https://www.uniprot.org/uniprot/P47835

LitCovid-sample-Enju

Id Subject Object Predicate Lexical cue
T27915 0-8 RB denotes Recently
T56144 8-9 -COMMA- denotes ,
T55915 10-19 NN denotes hybridoma
T72012 20-32 NNS denotes supernatants
T47163 33-43 VBG denotes containing
T24138 44-52 NN denotes antibody
T98139 53-64 NNS denotes repertoires
T66535 65-69 IN denotes from
T86473 70-79 VBN denotes immunized
T66245 80-90 JJ denotes transgenic
T17100 91-95 NNS denotes mice
T85324 96-100 WDT denotes that
T55347 101-108 VBP denotes express
T14738 109-112 DT denotes the
T52540 113-118 JJ denotes human
T35586 119-133 NN denotes immunoglobulin
T72563 134-139 JJ denotes heavy
T65069 140-143 CC denotes and
T5967 144-149 JJ denotes light
T98095 150-156 NNS denotes chains
T78221 157-160 CC denotes and
T28318 161-164 NN denotes rat
T19776 165-171 NN denotes origin
T32531 172-186 NN denotes immunoglobulin
T16968 187-195 NN denotes constant
T56920 196-203 NNS denotes regions
T36716 204-208 VBD denotes were
T74827 209-213 VBN denotes used
T21382 214-216 TO denotes to
T11788 217-223 VB denotes detect
T40665 224-234 NNS denotes antibodies
T56747 235-239 WDT denotes that
T54239 240-243 MD denotes can
T71867 244-249 VB denotes cross
T35671 250-260 VB denotes neutralize
T77445 261-267 NN denotes SARS-S
T34654 268-271 CC denotes and
T83470 272-280 NN denotes SARS-2-S
T76245 281-282 -LRB- denotes [
T33581 282-284 CD denotes 26
T80577 284-285 -RRB- denotes ]
T78516 287-290 CD denotes One
T34464 291-299 JJ denotes chimeric
T13041 300-305 NN denotes 47D11
T83927 306-310 NN denotes H2L2
T57345 311-319 NN denotes antibody
T44833 320-329 VBD denotes displayed
T94688 330-334 PDT denotes such
T52983 335-336 DT denotes a
T30646 337-355 JJ denotes cross-neutralizing
T37245 356-364 NN denotes activity
T11300 364-365 -COMMA- denotes ,
T30814 366-375 VBD denotes decreased
T23282 376-384 NN denotes syncytia
T72581 385-394 NN denotes formation
T71888 395-402 VBN denotes induced
T44111 403-405 IN denotes by
T7869 406-412 NN denotes SARS-S
T80909 413-416 CC denotes and
T58127 417-424 NN denotes SARS2-S
T9479 424-425 -COMMA- denotes ,
T96346 426-429 CC denotes and
T43362 430-435 MD denotes could
T48435 436-443 VB denotes protect
T44775 444-450 NN denotes VeroE6
T25625 451-456 NNS denotes cells
T19104 457-464 IN denotes against
T51640 465-471 NN denotes SARS-S
T22676 472-475 CC denotes and
T37470 476-483 NN denotes SARS2-S
T64695 484-495 VBD denotes pseudotyped
T26978 496-501 NN denotes virus
T79137 502-503 -LRB- denotes [
T95558 503-505 CD denotes 26
T95168 505-506 -RRB- denotes ]
T45371 508-510 PRP denotes It
T75403 511-514 MD denotes may
T86603 515-518 VB denotes lie
T91829 519-521 IN denotes in
T48175 522-525 PRP-DOLLAR- denotes its
T69338 526-533 JJ denotes similar
T68140 534-544 NNS denotes affinities
T76951 545-548 IN denotes for
T38362 549-560 VBG denotes interacting
T39715 561-565 IN denotes with
T48378 566-569 DT denotes the
T63623 570-574 JJ denotes same
T2491 575-581 NN denotes domain
T57621 582-584 IN denotes of
T77993 585-588 DT denotes the
T52886 589-591 NN denotes S1
T27554 592-599 NN denotes subunit
T41139 599-600 -COMMA- denotes ,
T99819 601-605 FW denotes i.e.
T40027 605-606 -COMMA- denotes ,
T73637 607-610 NN denotes S1B
T71055 610-611 -COMMA- denotes ,
T88888 612-614 IN denotes of
T40209 615-619 DT denotes each
T2572 620-626 NN denotes SARS-S
T97128 627-630 CC denotes and
T91104 631-639 NN denotes SARS-2-S
R33983 T74827 T27915 arg1Of used,Recently
R66835 T74827 T56144 arg1Of used,","
R79461 T72012 T55915 arg1Of supernatants,hybridoma
R93366 T72012 T47163 arg1Of supernatants,containing
R25704 T98139 T47163 arg2Of repertoires,containing
R90990 T98139 T24138 arg1Of repertoires,antibody
R94676 T98139 T66535 arg1Of repertoires,from
R63011 T17100 T66535 arg2Of mice,from
R10738 T17100 T86473 arg2Of mice,immunized
R74916 T17100 T66245 arg1Of mice,transgenic
R8726 T98139 T85324 arg1Of repertoires,that
R22914 T98139 T55347 arg1Of repertoires,express
R91506 T78221 T55347 arg2Of and,express
R63116 T78221 T14738 arg1Of and,the
R50898 T98095 T52540 arg1Of chains,human
R6996 T98095 T35586 arg1Of chains,immunoglobulin
R54748 T98095 T72563 arg1Of chains,heavy
R94533 T72563 T65069 arg1Of heavy,and
R51991 T5967 T65069 arg2Of light,and
R10518 T98095 T5967 arg1Of chains,light
R78842 T98095 T78221 arg1Of chains,and
R33937 T56920 T78221 arg2Of regions,and
R92294 T56920 T28318 arg1Of regions,rat
R87268 T56920 T19776 arg1Of regions,origin
R7737 T56920 T32531 arg1Of regions,immunoglobulin
R98342 T56920 T16968 arg1Of regions,constant
R65646 T72012 T36716 arg1Of supernatants,were
R67139 T74827 T36716 arg2Of used,were
R67837 T72012 T74827 arg2Of supernatants,used
R69341 T11788 T74827 arg3Of detect,used
R12801 T11788 T21382 arg1Of detect,to
R52958 T40665 T11788 arg2Of antibodies,detect
R77806 T40665 T56747 arg1Of antibodies,that
R37476 T40665 T54239 arg1Of antibodies,can
R87983 T35671 T54239 arg2Of neutralize,can
R24714 T40665 T71867 arg1Of antibodies,cross
R29418 T35671 T71867 arg2Of neutralize,cross
R8917 T40665 T35671 arg1Of antibodies,neutralize
R70086 T34654 T35671 arg2Of and,neutralize
R88560 T77445 T34654 arg1Of SARS-S,and
R74668 T83470 T34654 arg2Of SARS-2-S,and
R89642 T35671 T76245 arg1Of neutralize,[
R10178 T33581 T76245 arg2Of 26,[
R12224 T80577 T76245 arg3Of ],[
R55425 T57345 T78516 arg1Of antibody,One
R85824 T57345 T34464 arg1Of antibody,chimeric
R91166 T57345 T13041 arg1Of antibody,47D11
R74139 T57345 T83927 arg1Of antibody,H2L2
R37082 T57345 T44833 arg1Of antibody,displayed
R42165 T37245 T44833 arg2Of activity,displayed
R8404 T37245 T94688 arg1Of activity,such
R58851 T37245 T52983 arg1Of activity,a
R6725 T37245 T30646 arg1Of activity,cross-neutralizing
R48595 T44833 T11300 arg1Of displayed,","
R75181 T30814 T11300 arg2Of decreased,","
R32317 T57345 T30814 arg1Of antibody,decreased
R66912 T72581 T30814 arg2Of formation,decreased
R2953 T72581 T23282 arg1Of formation,syncytia
R53752 T80909 T71888 arg1Of and,induced
R39715 T72581 T71888 arg2Of formation,induced
R78219 T80909 T44111 arg2Of and,by
R96452 T7869 T80909 arg1Of SARS-S,and
R84017 T58127 T80909 arg2Of SARS2-S,and
R48482 T96346 T9479 arg1Of and,","
R37253 T11300 T96346 arg1Of ",",and
R96321 T48435 T96346 arg2Of protect,and
R73215 T57345 T43362 arg1Of antibody,could
R33694 T48435 T43362 arg2Of protect,could
R79302 T57345 T48435 arg1Of antibody,protect
R44320 T25625 T48435 arg2Of cells,protect
R54339 T25625 T44775 arg1Of cells,VeroE6
R74716 T48435 T19104 arg1Of protect,against
R67161 T22676 T19104 arg2Of and,against
R67960 T51640 T22676 arg1Of SARS-S,and
R58716 T37470 T22676 arg2Of SARS2-S,and
R42573 T22676 T64695 arg2Of and,pseudotyped
R23893 T26978 T64695 arg3Of virus,pseudotyped
R62516 T26978 T79137 arg1Of virus,[
R68991 T95558 T79137 arg2Of 26,[
R21425 T95168 T79137 arg3Of ],[
R57799 T45371 T75403 arg1Of It,may
R22045 T86603 T75403 arg2Of lie,may
R27208 T45371 T86603 arg1Of It,lie
R30853 T86603 T91829 arg1Of lie,in
R8563 T68140 T91829 arg2Of affinities,in
R84051 T68140 T48175 arg1Of affinities,its
R54251 T68140 T69338 arg1Of affinities,similar
R17475 T68140 T76951 arg1Of affinities,for
R24043 T38362 T76951 arg2Of interacting,for
R92728 T38362 T39715 arg1Of interacting,with
R17122 T2491 T39715 arg2Of domain,with
R47571 T2491 T48378 arg1Of domain,the
R29816 T2491 T63623 arg1Of domain,same
R3874 T2491 T57621 arg1Of domain,of
R51485 T27554 T57621 arg2Of subunit,of
R73905 T27554 T77993 arg1Of subunit,the
R30509 T27554 T52886 arg1Of subunit,S1
R24972 T68140 T41139 arg1Of affinities,","
R48015 T68140 T99819 arg1Of affinities,i.e.
R85163 T73637 T99819 arg2Of S1B,i.e.
R34990 T99819 T40027 arg1Of i.e.,","
R84082 T68140 T71055 arg1Of affinities,","
R73965 T68140 T88888 arg1Of affinities,of
R44270 T97128 T88888 arg2Of and,of
R2062 T97128 T40209 arg1Of and,each
R35318 T2572 T97128 arg1Of SARS-S,and
R89938 T91104 T97128 arg2Of SARS-2-S,and

LitCovid-sample-PD-GO-BP-0

Id Subject Object Predicate Lexical cue
T30 385-394 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T151 44-52 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T152 119-133 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T153 172-186 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T154 311-319 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T155 451-456 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T148 261-265 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T149 272-276 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T150 406-410 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T151 465-469 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T152 620-624 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T153 631-635 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-sample-GO-BP

Id Subject Object Predicate Lexical cue
T26 385-394 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T26 385-394 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T168 0-286 Sentence denotes Recently, hybridoma supernatants containing antibody repertoires from immunized transgenic mice that express the human immunoglobulin heavy and light chains and rat origin immunoglobulin constant regions were used to detect antibodies that can cross neutralize SARS-S and SARS-2-S [26].
T169 287-507 Sentence denotes One chimeric 47D11 H2L2 antibody displayed such a cross-neutralizing activity, decreased syncytia formation induced by SARS-S and SARS2-S, and could protect VeroE6 cells against SARS-S and SARS2-S pseudotyped virus [26].
T170 508-640 Sentence denotes It may lie in its similar affinities for interacting with the same domain of the S1 subunit, i.e., S1B, of each SARS-S and SARS-2-S.