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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 829-833 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T2 2754-2759 Body_part denotes Organ http://purl.org/sig/ont/fma/fma67498
T3 3342-3347 Body_part denotes joint http://purl.org/sig/ont/fma/fma7490
T4 3592-3596 Body_part denotes sole http://purl.org/sig/ont/fma/fma25000

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 829-833 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T2 2754-2759 Body_part denotes Organ http://purl.obolibrary.org/obo/UBERON_0000062

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T2 12-20 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 266-274 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T4 887-895 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 5791-5799 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 30-33 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 46-47 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 621-624 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T4 829-833 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T5 1075-1081 http://purl.obolibrary.org/obo/CLO_0053799 denotes 4], [5
T6 1247-1248 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1393-1399 http://purl.obolibrary.org/obo/CLO_0009609 denotes wishes
T8 1647-1652 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T9 1689-1690 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 1738-1739 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 1766-1767 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 1768-1773 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T13 1969-1970 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 2076-2079 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T15 2754-2759 http://purl.obolibrary.org/obo/UBERON_0003103 denotes Organ
T16 2863-2864 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 3342-3347 http://purl.obolibrary.org/obo/UBERON_0000982 denotes joint
T18 3342-3347 http://purl.obolibrary.org/obo/UBERON_0004905 denotes joint
T19 3590-3591 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 3775-3776 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 3950-3956 http://purl.obolibrary.org/obo/CLO_0053799 denotes 4], [5
T22 4047-4052 http://purl.obolibrary.org/obo/UBERON_0001456 denotes faced
T23 4183-4184 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 4538-4539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 4567-4569 http://purl.obolibrary.org/obo/CLO_0008337 denotes P4
T26 4928-4929 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 5035-5036 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 5141-5142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 5319-5320 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 5404-5410 http://purl.obolibrary.org/obo/CLO_0009609 denotes wishes
T31 5768-5769 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T32 5803-5804 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 4567-4569 Chemical denotes P4 http://purl.obolibrary.org/obo/CHEBI_35895

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 2631-2640 http://purl.obolibrary.org/obo/GO_0050890 denotes cognition

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-183 Sentence denotes The current COVID-19 pandemic has resulted in a significant increase in the number of hospitalised patients requiring mechanical ventilation for severe acute respiratory distress [1].
T4 184-347 Sentence denotes In France, public health measures were implemented rapidly to limit the spread of SARS-CoV-2 and to permit hospitals to increase the number of intensive care beds.
T5 348-601 Sentence denotes However, these actions and the overall response to this crisis have raised serious ethical concerns, particularly with respect to triage and prioritisation of access to intensive care units (ICUs) if the demand ultimately exceeds the supply of care [2].
T6 602-909 Sentence denotes Ethical reflection has been carried out at the national level by the National Consultative Ethics Committee ("Comité Consultatif National d’Ethique"), which provides advice toward guiding society and developing policies in the face of the ethical challenges such as those posed by the COVID-19 pandemic [3].
T7 910-1093 Sentence denotes Additional operational recommendations have been put forward by the leading medical societies in France (FLMS) to assist practitioners with ongoing decision-making [4], [5], [6], [7].
T8 1094-1429 Sentence denotes These recommendations serve to remind everyone of the need to respect the critical and fundamental ethical principles that could be easily overlooked in a pandemic situation; these principles include respect for the dignity of all, non-maleficence, collegiality in all decisions and respect for the wishes and autonomy of each patient.
T9 1430-1628 Sentence denotes All agree that the principle of distributive justice takes on an important role in this context, just as it is taken into account in everyday life apart from the stresses introduced by the pandemic.
T10 1629-1814 Sentence denotes Decisions need to focus not only on the individual needs of a given patient, but also the good of society as a whole; this would include a focus on maximising the number of lives saved.
T11 1815-2019 Sentence denotes If one is taking into account the number of years of life to be saved, as suggested by the American recommendations, patient age will of necessity become a major criterion with respect to decision-making.
T12 2020-2152 Sentence denotes Indeed, the Italian Society for Intensive Care Medicine has put forward age thresholds for prioritising access to critical care [8].
T13 2153-2337 Sentence denotes The recommendations made and criteria chosen by the FLMS were introduced with all necessary transparency so as to facilitate their acceptance amongst physicians and the general public.
T14 2338-2466 Sentence denotes The criteria emphasise the need to protect the most vulnerable patients from the risk of discrimination and arbitrary decisions.
T15 2467-2785 Sentence denotes Criteria commonly used for decisions related to ICU admission include frailty, presence of co-morbidities, prior level of personal autonomy, nutritional status and cognition; patient age is included amongst these factors as well as the severity of the disease assessed by the Sequential Organ Failure Assessment score.
T16 2786-2853 Sentence denotes It is critical to recognise that no specific criteria were defined.
T17 2854-3216 Sentence denotes This was a deliberate decision; ICU admissions ultimately depend on the ability to adapt to circumstances within given situations and contexts; amongst the latter issues, much depends on the availability of critical care beds, resuscitation equipment and the requisite scientific and medical knowledge required for appropriate care and treatment of this disease.
T18 3217-3548 Sentence denotes Likewise, no age threshold been defined beyond which access to ICU care would be denied, save for statements included in the joint recommendation of the French Society of Anaesthesia and Intensive Care (Société française d’anesthésie et de réanimation) and the French Military Health Service (Service de santé des armées; SSA) [4].
T19 3549-3753 Sentence denotes However, consideration of patient age as a sole criterion does not seem to be acceptable; the consideration of any single criterion considered in isolation would not be appropriate in these circumstances.
T20 3754-3958 Sentence denotes It would appear that a discussion of all relevant criteria should be carried out without reference to any specific hierarchy; several helpful decision-making tools have been proposed by the SFAR [4], [5].
T21 3959-4211 Sentence denotes The authors propose several levels of prioritisation with respect to ICU treatment when faced with limited capacity for critically ill patients; these are colour-coded as indicated, with each priority level corresponding to a specific course of action.
T22 4212-4431 Sentence denotes As shown, there are four levels of priority; amongst the criteria to consider are the definitive need for resuscitation and the probability that an individual will derive significant benefit from this level of care [4].
T23 4432-4903 Sentence denotes This categorisation strategy is similar to that recommended for surgical triage in war and in response to a disaster; for example, the P4 category here is analogous to surgical “expectants” who are those individuals who are too badly injured, whose chances of survival are very limited, and whose appropriate management would require the implementation of too great or even too uncertain levels of resources to the detriment of others who are less seriously affected [9].
T24 4904-5097 Sentence denotes This text also proposes a cognitive aid in the form of decision-support algorithms that consider the proposed criteria and suggest a course of action based on the level of priority established.
T25 5098-5439 Sentence denotes Although these decision-making aids can be a valuable resource for practitioners who are required to make difficult decisions in emergency situations, their use does not preclude thorough individualised assessments using a thoughtful, rational and collegial approach that take into consideration patients’ wishes regarding invasive ICU care.
T26 5440-5575 Sentence denotes These criteria are by necessity evolving and will depend largely on the context and the availability of appropriate hospital resources.
T27 5576-5751 Sentence denotes Likewise, regular reassessment of these criteria should be undertaken on an individual basis during the hospital stay; no decisions should be considered as fixed or immutable.
T28 5752-5929 Sentence denotes In the event of a new epidemic peak of COVID-19 or a future health crisis, these recommendations, if used properly, will remain valuable tools for frontline health care workers.
T29 5931-5938 Sentence denotes Funding
T30 5939-5960 Sentence denotes No financial support.
T31 5962-5984 Sentence denotes Disclosure of interest
T32 5985-6042 Sentence denotes The authors declare that they have no competing interest.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 158-178 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098