PMC:7204657 / 1424-2050
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
67 | 525-543 | Gene | denotes | C-reactive protein | Gene:1401 |
68 | 545-548 | Gene | denotes | CRP | Gene:1401 |
69 | 37-45 | Species | denotes | patients | Tax:9606 |
70 | 617-625 | Species | denotes | patients | Tax:9606 |
71 | 287-298 | Chemical | denotes | tocilizumab | MESH:C502936 |
72 | 415-426 | Chemical | denotes | tocilizumab | MESH:C502936 |
73 | 13-27 | Disease | denotes | critically ill | MESH:D016638 |
74 | 28-36 | Disease | denotes | COVID-19 | MESH:C000657245 |
75 | 311-319 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T10 | 100-110 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T11 | 145-155 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T12 | 259-269 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T13 | 464-474 | Body_part | denotes | intestinal | http://purl.org/sig/ont/fma/fma7199 |
T14 | 536-543 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T16 | 28-36 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T17 | 259-281 | Disease | denotes | intestinal perforation | http://purl.obolibrary.org/obo/MONDO_0006807 |
T18 | 311-319 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T19 | 464-486 | Disease | denotes | intestinal perforation | http://purl.obolibrary.org/obo/MONDO_0006807 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18 | 100-110 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T19 | 100-110 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
T20 | 145-155 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T21 | 145-155 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
T22 | 259-269 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T23 | 259-269 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
T24 | 464-474 | http://purl.obolibrary.org/obo/UBERON_0000160 | denotes | intestinal |
T25 | 464-474 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | intestinal |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T9 | 287-298 | Chemical | denotes | tocilizumab | http://purl.obolibrary.org/obo/CHEBI_64360 |
T10 | 415-426 | Chemical | denotes | tocilizumab | http://purl.obolibrary.org/obo/CHEBI_64360 |
T11 | 536-543 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 442-462 | http://purl.obolibrary.org/obo/GO_0006953 | denotes | acute phase response |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T13 | 0-174 | Sentence | denotes | Furthermore, critically ill COVID-19 patients may have altered hemodynamics, potentially leading to intestinal hypoperfusion that can compromise intestinal mucosal integrity. |
T14 | 175-403 | Sentence | denotes | More studies are required to evaluate whether these variables influence the risk of intestinal perforation with tocilizumab in critical COVID-19 cases; however, clinicians should be aware of the potential for this adverse event. |
T15 | 404-626 | Sentence | denotes | Lastly, as tocilizumab attenuates the acute phase response, intestinal perforation may not necessarily cause significant C-reactive protein (CRP) elevation and may initially go unnoticed in sedated and ventilated patients. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T8 | 259-281 | Phenotype | denotes | intestinal perforation | http://purl.obolibrary.org/obo/HP_0031368 |
T9 | 442-462 | Phenotype | denotes | acute phase response | http://purl.obolibrary.org/obo/HP_0033331 |
T10 | 464-486 | Phenotype | denotes | intestinal perforation | http://purl.obolibrary.org/obo/HP_0031368 |