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PMC:7201239 / 765-2254 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
41 209-213 Gene denotes ACE2 Gene:59272
42 225-229 Gene denotes ACE2 Gene:59272
43 335-339 Gene denotes ACE2 Gene:59272
44 571-575 Gene denotes ACE2 Gene:59272
45 594-608 Gene denotes angiotensin II Gene:183
56 134-140 Species denotes Humans Tax:9606
57 271-276 Species denotes human Tax:9606
58 414-420 Species denotes people Tax:9606
59 632-640 Species denotes patients Tax:9606
60 114-125 Chemical denotes aldosterone MESH:D000450
63 424-444 Disease denotes SARS-CoV-2 infection MESH:C000657245
64 468-476 Disease denotes COVID-19 MESH:C000657245
65 612-631 Disease denotes SARS-CoV-2 infected MESH:C000657245
66 757-765 Disease denotes COVID-19 MESH:C000657245
67 786-799 Disease denotes heart failure MESH:D006333
93 1215-1248 Gene denotes angiotensin I converting enzyme 2 Gene:59272
94 1250-1254 Gene denotes ACE2 Gene:59272
95 1326-1330 Gene denotes ACE2 Gene:59272
96 1373-1377 Gene denotes ACE2 Gene:59272
98 845-858 Species denotes coronaviruses Tax:11118
99 932-938 Species denotes humans Tax:9606
100 967-977 Species denotes SARS-CoV-2 Tax:2697049
101 981-996 Species denotes Betacoronavirus Tax:694002
102 1032-1040 Species denotes patients Tax:9606
103 1177-1187 Species denotes SARS-CoV-2 Tax:2697049
104 1209-1214 Species denotes human Tax:9606
105 1362-1368 Species denotes humans Tax:9606
108 895-915 Disease denotes respiratory diseases MESH:D012140
109 1041-1052 Disease denotes lung injury MESH:D055370
110 1067-1086 Disease denotes multi-organ failure MESH:D009102
111 1092-1121 Disease denotes adverse myocardial remodeling MESH:D020257
112 1123-1140 Disease denotes myocardial stress MESH:D000079225
113 1146-1160 Disease denotes cardiomyopathy MESH:D009202

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T3 25-40 Body_part denotes surface of lung http://purl.org/sig/ont/fma/fma17530
T4 41-57 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T5 52-57 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T6 68-75 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T7 723-728 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T8 786-791 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T9 1041-1045 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 1073-1078 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T11 1291-1299 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T12 1300-1311 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T13 1443-1448 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T14 1450-1463 Body_part denotes blood vessels http://purl.org/sig/ont/fma/fma63183
T15 1450-1455 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T16 1465-1471 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T17 1476-1482 Body_part denotes testis http://purl.org/sig/ont/fma/fma7210

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T2 36-40 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T3 723-728 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T4 786-791 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T5 1041-1045 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 1073-1078 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T7 1422-1428 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T8 1443-1463 Body_part denotes heart, blood vessels http://purl.obolibrary.org/obo/UBERON_0003498
T9 1443-1448 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T10 1450-1455 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T11 1456-1463 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055
T12 1465-1471 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T13 1476-1482 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T15 424-432 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 424-428 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T17 435-444 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T18 468-476 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 612-620 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 612-616 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 717-737 Disease denotes multi-organ failures http://purl.obolibrary.org/obo/MONDO_0043726
T22 757-765 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T23 786-799 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T24 895-915 Disease denotes respiratory diseases http://purl.obolibrary.org/obo/MONDO_0005087
T25 967-975 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 967-971 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T27 1046-1052 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T28 1067-1086 Disease denotes multi-organ failure http://purl.obolibrary.org/obo/MONDO_0043726
T29 1134-1160 Disease denotes stress, and cardiomyopathy http://purl.obolibrary.org/obo/MONDO_0019018
T30 1146-1160 Disease denotes cardiomyopathy http://purl.obolibrary.org/obo/MONDO_0004994
T31 1177-1185 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T32 1177-1181 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T14 36-57 http://purl.obolibrary.org/obo/CL_0000082 denotes lung epithelial cells
T15 134-140 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Humans
T16 271-276 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T17 538-543 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T18 723-728 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T19 786-791 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T20 786-791 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T21 786-791 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T22 786-791 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T23 932-938 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T24 979-980 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 1005-1006 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T26 1041-1045 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T27 1041-1045 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T28 1073-1078 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T29 1207-1208 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 1209-1214 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T31 1362-1368 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T32 1422-1428 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T33 1443-1448 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T34 1443-1448 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T35 1443-1448 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T36 1443-1448 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T37 1450-1463 http://purl.obolibrary.org/obo/UBERON_0001981 denotes blood vessels
T38 1450-1463 http://www.ebi.ac.uk/efo/EFO_0000817 denotes blood vessels
T39 1465-1471 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T40 1465-1471 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T41 1465-1471 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T42 1476-1482 http://www.ebi.ac.uk/efo/EFO_0000984 denotes testis

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T4 102-113 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T5 114-125 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T7 594-608 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T10 594-605 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T11 606-608 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T12 1215-1226 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 786-799 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T3 1146-1160 Phenotype denotes cardiomyopathy http://purl.obolibrary.org/obo/HP_0001638

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T8 134-214 Sentence denotes Humans are not equal with respect to the expression levels of the cellular ACE2.
T9 215-289 Sentence denotes Moreover, ACE2 polymorphisms were recently described in human populations.
T10 290-485 Sentence denotes Here we review the most recent evidence that ACE2 expression and/or polymorphism could influence both the susceptibility of people to SARS-CoV-2 infection and the outcome of the COVID-19 disease.
T11 486-800 Sentence denotes Further exploration of the relationship between the virus, the peptidase function of ACE2 and the levels of angiotensin II in SARS-CoV-2 infected patients should help to better understand the pathophysiology of the disease and the multi-organ failures observed in severe COVID-19 cases, particularly heart failure.
T12 802-814 Sentence denotes Introduction
T13 815-939 Sentence denotes Over the past 20 years, seven coronaviruses responsible for more or less severe respiratory diseases have emerged in humans.

2_test

Id Subject Object Predicate Lexical cue
32414646-31978945-62239755 1161-1162 31978945 denotes 1
32414646-31986264-62239756 1165-1166 31986264 denotes 2