PMC:7201239 / 7526-8596
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 348 | 31-36 | Gene | denotes | ACE-2 | Gene:59272 |
| 349 | 127-131 | Gene | denotes | ACE2 | Gene:59272 |
| 350 | 201-205 | Gene | denotes | ACE2 | Gene:59272 |
| 351 | 270-274 | Gene | denotes | ACE2 | Gene:59272 |
| 352 | 551-555 | Gene | denotes | ACE2 | Gene:59272 |
| 353 | 643-647 | Gene | denotes | ACE2 | Gene:59272 |
| 354 | 776-780 | Gene | denotes | ACE2 | Gene:59272 |
| 355 | 863-867 | Gene | denotes | ACE2 | Gene:59272 |
| 356 | 1002-1006 | Gene | denotes | ACE2 | Gene:59272 |
| 357 | 4-9 | Species | denotes | human | Tax:9606 |
| 358 | 64-69 | Species | denotes | human | Tax:9606 |
| 359 | 251-256 | Species | denotes | human | Tax:9606 |
| 360 | 535-540 | Species | denotes | human | Tax:9606 |
| 361 | 758-761 | Species | denotes | men | Tax:9606 |
| 362 | 810-815 | Species | denotes | women | Tax:9606 |
| 363 | 831-837 | Species | denotes | people | Tax:9606 |
| 364 | 70-83 | Disease | denotes | heart failure | MESH:D006333 |
| 365 | 88-96 | Disease | denotes | lymphoma | MESH:D008223 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T36 | 70-75 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T37 | 132-136 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T38 | 176-181 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T39 | 257-266 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
| T40 | 296-307 | Body_part | denotes | enterocytes | http://purl.org/sig/ont/fma/fma62122 |
| T41 | 315-330 | Body_part | denotes | small intestine | http://purl.org/sig/ont/fma/fma7200 |
| T42 | 378-381 | Body_part | denotes | gut | http://purl.org/sig/ont/fma/fma7199 |
| T43 | 476-507 | Body_part | denotes | endothelial cells, and arterial | http://purl.org/sig/ont/fma/fma67761 |
| T44 | 476-493 | Body_part | denotes | endothelial cells | http://purl.org/sig/ont/fma/fma66772 |
| T45 | 488-493 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T46 | 515-521 | Body_part | denotes | muscle | http://purl.org/sig/ont/fma/fma32558 |
| T47 | 541-545 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T48 | 556-563 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T49 | 590-598 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T50 | 610-614 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T51 | 615-620 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T52 | 673-689 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T53 | 684-689 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T54 | 693-704 | Body_part | denotes | oral mucosa | http://purl.org/sig/ont/fma/fma59660 |
| T55 | 698-704 | Body_part | denotes | mucosa | http://purl.org/sig/ont/fma/fma85355 |
| T56 | 715-719 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T57 | 720-723 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T58 | 781-785 | Body_part | denotes | mRNA | http://purl.org/sig/ont/fma/fma67122 |
| T59 | 800-804 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T21 | 70-75 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T22 | 315-330 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T23 | 321-330 | Body_part | denotes | intestine | http://purl.obolibrary.org/obo/UBERON_0000160 |
| T24 | 541-545 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T25 | 610-614 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T26 | 698-704 | Body_part | denotes | mucosa | http://purl.obolibrary.org/obo/UBERON_0000344 |
| T27 | 800-804 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T84 | 70-83 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T85 | 88-96 | Disease | denotes | lymphoma | http://purl.obolibrary.org/obo/MONDO_0005062 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T106 | 4-9 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T107 | 64-69 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T108 | 70-75 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T109 | 70-75 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T110 | 70-75 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T111 | 70-75 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T112 | 132-136 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T113 | 176-181 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T114 | 228-229 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T115 | 251-256 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T116 | 257-266 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
| T117 | 267-269 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T118 | 315-330 | http://purl.obolibrary.org/obo/UBERON_0002108 | denotes | small intestine |
| T119 | 378-381 | http://purl.obolibrary.org/obo/UBERON_0001007 | denotes | gut |
| T120 | 378-381 | http://purl.obolibrary.org/obo/UBERON_0001555 | denotes | gut |
| T121 | 378-381 | http://www.ebi.ac.uk/efo/EFO_0000834 | denotes | gut |
| T122 | 396-404 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T123 | 405-407 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T124 | 456-464 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arterial |
| T125 | 456-464 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arterial |
| T126 | 476-493 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cells |
| T127 | 499-507 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arterial |
| T128 | 499-507 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arterial |
| T129 | 515-521 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | muscle |
| T130 | 515-521 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | muscle |
| T131 | 515-521 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | muscle |
| T132 | 515-521 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | muscle |
| T133 | 522-524 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T134 | 535-540 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T135 | 541-545 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T136 | 541-545 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T137 | 599-609 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T138 | 610-614 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T139 | 610-614 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T140 | 615-620 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T141 | 673-683 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T142 | 684-689 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T143 | 698-704 | http://purl.obolibrary.org/obo/UBERON_0000344 | denotes | mucosa |
| T144 | 715-719 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T145 | 767-768 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T146 | 800-804 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T147 | 800-804 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T148 | 1068-1070 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T22 | 382-395 | Chemical | denotes | antimicrobial | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T23 | 396-404 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T24 | 556-563 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T25 | 587-589 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T12 | 70-83 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T13 | 88-96 | Phenotype | denotes | lymphoma | http://purl.obolibrary.org/obo/HP_0002665 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T29 | 0-1070 | Sentence | denotes | The human monocarboxypeptidase ACE-2 was originally cloned from human heart failure and lymphoma cDNA libraries.7 Although the ACE2 gene is usually considered silent in immune cells, the expression of ACE2 mRNAs was reported in a subset of CD14+ CD16-human monocytes.34 ACE2 is also expressed by enterocytes of the small intestine and expected to regulate the expression of the gut antimicrobial peptides.35 Moreover, this peptidase is also present on the arterial and venous endothelial cells, and arterial smooth muscle.36 In normal human lung, the ACE2 protein is found on type I and II alveolar epithelial lung cells.37 High expression of ACE2 was also reported on the epithelial cells of oral mucosa.38 Single-cell RNA-seq analysis indicated that Asian men have a higher ACE2 mRNA expression in lung than women and that Asian people express higher amount of ACE2 than Caucasian and African American populations,39 but this observation remains controversial.40 Until recently, the genetic basis of ACE2 expression in different populations remained largely unknown.41 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32414646-10969042-62239777 | 112-113 | 10969042 | denotes | 7 |
| 32414646-25707554-62239778 | 267-269 | 25707554 | denotes | 34 |
| 32414646-15141377-62239779 | 522-524 | 15141377 | denotes | 36 |
| 32414646-32094336-62239780 | 705-707 | 32094336 | denotes | 38 |