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PMC:7200337 / 9095-10644 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
32505227-25135833-46575232 668-672 25135833 denotes 2014
32505227-19380580-46575233 930-934 19380580 denotes 2009
32505227-26631542-46575234 974-978 26631542 denotes 2015
32505227-17761676-46575235 1113-1117 17761676 denotes 2007
32505227-17108024-46575236 1144-1148 17108024 denotes 2007
32505227-19369340-46575237 1238-1242 19369340 denotes 2009
32505227-29370303-46575238 1288-1292 29370303 denotes 2018
32505227-19838190-46575240 1383-1387 19838190 denotes 2009
32505227-26311885-46575241 1427-1431 26311885 denotes 2015
T99744 668-672 25135833 denotes 2014
T89021 930-934 19380580 denotes 2009
T58194 974-978 26631542 denotes 2015
T64611 1113-1117 17761676 denotes 2007
T46471 1144-1148 17108024 denotes 2007
T33023 1238-1242 19369340 denotes 2009
T71391 1288-1292 29370303 denotes 2018
T25270 1383-1387 19838190 denotes 2009
T42335 1427-1431 26311885 denotes 2015

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T62070 247-256 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T34871 343-351 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T98576 416-424 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T56607 862-869 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T85573 987-995 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T13179 1182-1190 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T62 332-340 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T63 453-461 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T64 612-620 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 688-696 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 849-857 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 1007-1015 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 1206-1214 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 1328-1336 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T46552 10-20 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T26255 42-51 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T87993 130-132 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T52388 130-132 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T27533 433-442 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T78168 500-509 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T65422 645-654 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T77228 720-729 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T35185 788-797 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T5869 899-908 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T15916 1154-1156 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T55083 1154-1156 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T42053 1288-1292 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T27 127-129 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T30 141-151 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T31 343-351 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T32 416-424 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T33 862-869 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34 987-995 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T35 1018-1021 Chemical denotes PLP http://purl.obolibrary.org/obo/CHEBI_18405
T36 1151-1153 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T39 1182-1190 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T40 1217-1220 Chemical denotes PLP http://purl.obolibrary.org/obo/CHEBI_18405
T41 1514-1523 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T37 42-60 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T38 42-51 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T39 77-92 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T40 96-117 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factors
T41 96-109 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T42 206-219 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T43 433-451 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T44 433-442 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T45 500-509 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T46 645-654 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T47 720-729 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T48 743-747 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T49 801-805 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T50 894-898 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T51 899-908 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T52 1054-1069 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T53 1469-1482 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T54 1487-1498 http://purl.obolibrary.org/obo/GO_0006412 denotes translation

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
329 429-432 Gene denotes PRR Gene:10159
330 548-553 Gene denotes Tom70 Gene:9868
331 640-644 Gene denotes MAVS Gene:57506
332 743-747 Gene denotes TBK1 Gene:29110
333 778-783 Gene denotes RNF41 Gene:10193
334 801-805 Gene denotes TBK1 Gene:29110
335 810-814 Gene denotes IRF3 Gene:3661
336 894-898 Gene denotes TBK1 Gene:29110
337 954-959 Gene denotes ORF4b Gene:14254597
338 1037-1041 Gene denotes ORF6 Gene:43740572
339 1049-1053 Gene denotes IRF3 Gene:3661
340 1257-1262 Gene denotes ORF4b Gene:14254597
341 1267-1271 Gene denotes ORF5 Gene:51503
342 1339-1343 Gene denotes NSP1 Gene:10045
343 1402-1406 Gene denotes NSP1 Gene:10045
344 1217-1220 Gene denotes PLP Gene:57026
345 1018-1021 Gene denotes PLP Gene:57026
346 879-881 Gene denotes to Gene:6999
347 203-205 Gene denotes to Gene:6999
348 70-72 Gene denotes to Gene:6999
349 518-522 Gene denotes MAVS Gene:57506
350 332-342 Species denotes SARS-CoV-2 Tax:2697049
351 453-463 Species denotes SARS-CoV-2 Tax:2697049
352 612-620 Species denotes SARS-CoV Tax:694009
353 688-698 Species denotes SARS-CoV-2 Tax:2697049
354 849-857 Species denotes SARS-CoV Tax:694009
355 945-953 Species denotes MERS-CoV Tax:1335626
356 1007-1015 Species denotes SARS-CoV Tax:694009
357 1178-1181 Species denotes CoV Tax:11118
358 1206-1214 Species denotes SARS-CoV Tax:694009
359 1248-1256 Species denotes MERS-CoV Tax:1335626
360 1328-1336 Species denotes SARS-CoV Tax:694009
361 1394-1401 Species denotes ERS-CoV Tax:1335626

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T54 0-257 Sentence denotes Following activation, RLR and TLRs induce signaling cascades, leading to the phosphorylation of transcription factors, such as NF-kB and the interferon-regulatory factor family (IRF), ultimately leading to transcription of IFN and proinflammatory cytokines.
T55 258-452 Sentence denotes Although no experimental studies have delineated the precise functions of SARS-CoV-2 proteins, proteomic studies have demonstrated interactions between viral proteins and PRR signaling cascades.
T56 453-674 Sentence denotes SARS-CoV-2 ORF9b indirectly interacts with the signaling adaptor MAVS via its association with Tom70 (Gordon et al., 2020), consistent with prior reports that SARS-CoV-1 ORF9b suppresses MAVS signaling (Shi et al., 2014).
T57 675-837 Sentence denotes Furthermore, SARS-CoV-2 NSP13 interacts with signaling intermediate TBK1, and NSP15 is associated with RNF41, an activator of TBK1 and IRF3 (Gordon et al., 2020).
T58 838-980 Sentence denotes Similarly, SARS-CoV-1 M protein is known to inhibit the TBK1 signaling complex (Siu et al., 2009), as does MERS-CoV ORF4b (Yang et al., 2015).
T59 981-1150 Sentence denotes Other proteins, including SARS-CoV-1 PLP, N, ORF3b, and ORF6, block IRF3 phosphorylation and nuclear translocation (Devaraj et al., 2007, Kopecky-Bromberg et al., 2007).
T60 1151-1191 Sentence denotes NF-kB is also inhibited by CoV proteins.
T61 1192-1318 Sentence denotes These include SARS-CoV-1 PLP (Frieman et al., 2009) and MERS-CoV ORF4b and ORF5 (Canton et al., 2018, Menachery et al., 2017).
T62 1319-1549 Sentence denotes Finally, SARS-CoV-1 NSP1 (Huang et al., 2011a, Kamitani et al., 2009) and MERS-CoV NSP1 (Lokugamage et al., 2015) initiate general inhibition of host transcription and translation, thus limiting antiviral defenses nonspecifically.