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PMC:7200337 / 6033-7178 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
32505227-23029269-46575210 256-260 23029269 denotes 2012
32505227-20020050-46575211 279-283 20020050 denotes 2009
32505227-19380580-46575212 297-301 19380580 denotes 2009
32505227-17715225-46575213 320-324 17715225 denotes 2007
T72435 256-260 23029269 denotes 2012
T21841 279-283 20020050 denotes 2009
T20061 297-301 19380580 denotes 2009
T44255 320-324 17715225 denotes 2007

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T27355 9-18 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T45987 447-451 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T57688 477-482 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T89729 832-840 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T52 48-63 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T53 54-63 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T54 184-192 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T55 327-335 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T56 561-569 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T57 1091-1099 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T51889 29-30 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76060 133-142 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T51305 354-355 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41210 447-457 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T80754 477-482 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T25559 488-489 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98223 490-496 http://purl.obolibrary.org/obo/NCBITaxon_9669 denotes ferret
T66742 858-864 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T27278 1027-1036 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T18 1016-1026 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T20 48-63 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T21 133-142 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T22 832-850 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine secretion
T23 841-850 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T24 858-877 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T25 865-877 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T26 919-941 http://purl.obolibrary.org/obo/GO_0045087 denotes Innate Immune Response
T27 926-941 http://purl.obolibrary.org/obo/GO_0006955 denotes Immune Response
T28 983-996 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T29 1027-1036 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
199 946-959 Species denotes Coronaviruses Tax:11118
202 1091-1099 Species denotes SARS-CoV Tax:694009
203 1106-1114 Species denotes MERS-CoV Tax:1335626
215 631-633 Gene denotes to Gene:6999
216 816-819 Gene denotes PRR Gene:10159
217 65-69 Species denotes CoVs Tax:11118
218 184-192 Species denotes SARS-CoV Tax:694009
219 327-337 Species denotes SARS-CoV-2 Tax:2697049
220 490-496 Species denotes ferret Tax:9669
221 540-548 Species denotes patients Tax:9606
222 748-752 Species denotes CoVs Tax:11118
223 48-63 Disease denotes viral infection MESH:D001102
224 438-446 Disease denotes infected MESH:D007239
225 561-569 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T35 0-143 Sentence denotes As these cytokines represent a major barrier to viral infection, CoVs have evolved several mechanisms to inhibit IFN-I induction and signaling.
T36 144-326 Sentence denotes Numerous studies have demonstrated that SARS-CoV-1 suppresses IFN release in vitro and in vivo (Cameron et al., 2012, Minakshi et al., 2009, Siu et al., 2009, Wathelet et al., 2007).
T37 327-530 Sentence denotes SARS-CoV-2 likely achieves a similar effect, as suggested by the lack of robust type I/III IFN signatures from infected cell lines, primary bronchial cells, and a ferret model (Blanco-Melo et al., 2020).
T38 531-680 Sentence denotes In fact, patients with severe COVID-19 demonstrate remarkably impaired IFN-I signatures as compared to mild or moderate cases (Hadjadj et al., 2020).
T39 681-890 Sentence denotes As is often the case, there are multiple mechanisms of evasion for CoVs, with viral factors antagonizing each step of the pathway from PRR sensing and cytokine secretion to IFN signal transduction (Figure 1 ).
T40 891-970 Sentence denotes Figure 1 Mechanisms of Host Innate Immune Response and Coronaviruses Antagonism
T41 971-1145 Sentence denotes Overview of innate immune sensing (left) and interferon signaling (right), annotated with the known mechanisms by which SARS-CoV-1 and MERS-CoV antagonize the pathways (red).