PMC:7200337 / 43118-43363 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T430","span":{"begin":14,"end":19},"obj":"Body_part"}],"attributes":[{"id":"A430","pred":"fma_id","subj":"T430","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T274","span":{"begin":30,"end":38},"obj":"Disease"}],"attributes":[{"id":"A274","pred":"mondo_id","subj":"T274","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T556","span":{"begin":12,"end":19},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T557","span":{"begin":55,"end":64},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T558","span":{"begin":81,"end":82},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T227","span":{"begin":168,"end":170},"obj":"Chemical"}],"attributes":[{"id":"A227","pred":"chebi_id","subj":"T227","obj":"http://purl.obolibrary.org/obo/CHEBI_74756"}],"text":"In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1451","span":{"begin":177,"end":182},"obj":"Gene"},{"id":"1457","span":{"begin":44,"end":46},"obj":"Gene"},{"id":"1459","span":{"begin":30,"end":38},"obj":"Disease"},{"id":"1460","span":{"begin":232,"end":244},"obj":"Disease"}],"attributes":[{"id":"A1451","pred":"tao:has_database_id","subj":"1451","obj":"Gene:84868"},{"id":"A1457","pred":"tao:has_database_id","subj":"1457","obj":"Gene:6999"},{"id":"A1459","pred":"tao:has_database_id","subj":"1459","obj":"MESH:C000657245"},{"id":"A1460","pred":"tao:has_database_id","subj":"1460","obj":"MESH:D064420"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity."}

{"project":"LitCovid-sentences","denotations":[{"id":"T231","span":{"begin":0,"end":245},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity."}