PMC:7200337 / 42998-43367 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T430","span":{"begin":134,"end":139},"obj":"Body_part"}],"attributes":[{"id":"A430","pred":"fma_id","subj":"T430","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"nes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).\nIn summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity. Con"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T274","span":{"begin":150,"end":158},"obj":"Disease"}],"attributes":[{"id":"A274","pred":"mondo_id","subj":"T274","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"nes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).\nIn summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity. Con"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T556","span":{"begin":132,"end":139},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T557","span":{"begin":175,"end":184},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T558","span":{"begin":201,"end":202},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"nes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).\nIn summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity. Con"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T227","span":{"begin":288,"end":290},"obj":"Chemical"}],"attributes":[{"id":"A227","pred":"chebi_id","subj":"T227","obj":"http://purl.obolibrary.org/obo/CHEBI_74756"}],"text":"nes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).\nIn summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity. Con"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1417","span":{"begin":12,"end":16},"obj":"Gene"},{"id":"1418","span":{"begin":18,"end":22},"obj":"Gene"},{"id":"1419","span":{"begin":28,"end":32},"obj":"Gene"},{"id":"1420","span":{"begin":57,"end":62},"obj":"Gene"},{"id":"1421","span":{"begin":67,"end":71},"obj":"Gene"},{"id":"1451","span":{"begin":297,"end":302},"obj":"Gene"},{"id":"1457","span":{"begin":164,"end":166},"obj":"Gene"},{"id":"1459","span":{"begin":150,"end":158},"obj":"Disease"},{"id":"1460","span":{"begin":352,"end":364},"obj":"Disease"}],"attributes":[{"id":"A1417","pred":"tao:has_database_id","subj":"1417","obj":"Gene:3001"},{"id":"A1418","pred":"tao:has_database_id","subj":"1418","obj":"Gene:3002"},{"id":"A1419","pred":"tao:has_database_id","subj":"1419","obj":"Gene:3003"},{"id":"A1420","pred":"tao:has_database_id","subj":"1420","obj":"Gene:3821"},{"id":"A1421","pred":"tao:has_database_id","subj":"1421","obj":"Gene:6375"},{"id":"A1451","pred":"tao:has_database_id","subj":"1451","obj":"Gene:84868"},{"id":"A1457","pred":"tao:has_database_id","subj":"1457","obj":"Gene:6999"},{"id":"A1459","pred":"tao:has_database_id","subj":"1459","obj":"MESH:C000657245"},{"id":"A1460","pred":"tao:has_database_id","subj":"1460","obj":"MESH:D064420"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"nes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).\nIn summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity. Con"}

{"project":"LitCovid-sentences","denotations":[{"id":"T231","span":{"begin":120,"end":365},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"nes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).\nIn summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity. Con"}