PMC:7200337 / 41580-41957 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T417","span":{"begin":65,"end":70},"obj":"Body_part"},{"id":"T418","span":{"begin":144,"end":149},"obj":"Body_part"},{"id":"T419","span":{"begin":175,"end":183},"obj":"Body_part"}],"attributes":[{"id":"A417","pred":"fma_id","subj":"T417","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A418","pred":"fma_id","subj":"T418","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A419","pred":"fma_id","subj":"T419","obj":"http://purl.org/sig/ont/fma/fma84050"}],"text":"Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T268","span":{"begin":295,"end":298},"obj":"Disease"}],"attributes":[{"id":"A268","pred":"mondo_id","subj":"T268","obj":"http://purl.obolibrary.org/obo/MONDO_0016692"},{"id":"A269","pred":"mondo_id","subj":"T268","obj":"http://purl.obolibrary.org/obo/MONDO_0018687"}],"text":"Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T533","span":{"begin":51,"end":54},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T534","span":{"begin":59,"end":62},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T535","span":{"begin":63,"end":70},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T536","span":{"begin":142,"end":149},"obj":"http://purl.obolibrary.org/obo/CL_0000084"}],"text":"Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T213","span":{"begin":268,"end":275},"obj":"Chemical"},{"id":"T214","span":{"begin":276,"end":285},"obj":"Chemical"},{"id":"T215","span":{"begin":286,"end":293},"obj":"Chemical"},{"id":"T217","span":{"begin":295,"end":298},"obj":"Chemical"},{"id":"T220","span":{"begin":304,"end":313},"obj":"Chemical"}],"attributes":[{"id":"A213","pred":"chebi_id","subj":"T213","obj":"http://purl.obolibrary.org/obo/CHEBI_8116"},{"id":"A214","pred":"chebi_id","subj":"T214","obj":"http://purl.obolibrary.org/obo/CHEBI_30807"},{"id":"A215","pred":"chebi_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/CHEBI_30089"},{"id":"A216","pred":"chebi_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/CHEBI_47622"},{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_37537"},{"id":"A218","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_53780"},{"id":"A219","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_60755"},{"id":"A220","pred":"chebi_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/CHEBI_63954"}],"text":"Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1399","span":{"begin":51,"end":54},"obj":"Gene"},{"id":"1400","span":{"begin":59,"end":62},"obj":"Gene"},{"id":"1401","span":{"begin":212,"end":217},"obj":"Gene"},{"id":"1402","span":{"begin":222,"end":227},"obj":"Gene"},{"id":"1423","span":{"begin":33,"end":35},"obj":"Gene"},{"id":"1429","span":{"begin":89,"end":97},"obj":"Species"},{"id":"1433","span":{"begin":268,"end":293},"obj":"Chemical"},{"id":"1434","span":{"begin":295,"end":298},"obj":"Chemical"},{"id":"1435","span":{"begin":304,"end":313},"obj":"Chemical"},{"id":"1436","span":{"begin":74,"end":88},"obj":"Disease"}],"attributes":[{"id":"A1399","pred":"tao:has_database_id","subj":"1399","obj":"Gene:920"},{"id":"A1400","pred":"tao:has_database_id","subj":"1400","obj":"Gene:925"},{"id":"A1401","pred":"tao:has_database_id","subj":"1401","obj":"Gene:3458"},{"id":"A1402","pred":"tao:has_database_id","subj":"1402","obj":"Gene:7124"},{"id":"A1423","pred":"tao:has_database_id","subj":"1423","obj":"Gene:6999"},{"id":"A1429","pred":"tao:has_database_id","subj":"1429","obj":"Tax:9606"},{"id":"A1433","pred":"tao:has_database_id","subj":"1433","obj":"MESH:D013755"},{"id":"A1434","pred":"tao:has_database_id","subj":"1434","obj":"MESH:D013755"},{"id":"A1435","pred":"tao:has_database_id","subj":"1435","obj":"MESH:D015759"},{"id":"A1436","pred":"tao:has_database_id","subj":"1436","obj":"MESH:D016638"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T225","span":{"begin":0,"end":377},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b)."}