PMC:7200337 / 35737-36199 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T366","span":{"begin":135,"end":142},"obj":"Body_part"},{"id":"T367","span":{"begin":180,"end":183},"obj":"Body_part"},{"id":"T368","span":{"begin":235,"end":243},"obj":"Body_part"},{"id":"T369","span":{"begin":336,"end":341},"obj":"Body_part"},{"id":"T370","span":{"begin":348,"end":355},"obj":"Body_part"}],"attributes":[{"id":"A366","pred":"fma_id","subj":"T366","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A367","pred":"fma_id","subj":"T367","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A368","pred":"fma_id","subj":"T368","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A369","pred":"fma_id","subj":"T369","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A370","pred":"fma_id","subj":"T370","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T237","span":{"begin":88,"end":92},"obj":"Disease"}],"attributes":[{"id":"A237","pred":"mondo_id","subj":"T237","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T425","span":{"begin":57,"end":64},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T426","span":{"begin":287,"end":288},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T427","span":{"begin":322,"end":325},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T428","span":{"begin":330,"end":333},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T429","span":{"begin":334,"end":341},"obj":"http://purl.obolibrary.org/obo/CL_0000084"}],"text":"This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T172","span":{"begin":57,"end":64},"obj":"Chemical"},{"id":"T173","span":{"begin":135,"end":142},"obj":"Chemical"},{"id":"T174","span":{"begin":192,"end":194},"obj":"Chemical"},{"id":"T175","span":{"begin":235,"end":243},"obj":"Chemical"},{"id":"T176","span":{"begin":248,"end":255},"obj":"Chemical"},{"id":"T177","span":{"begin":348,"end":355},"obj":"Chemical"}],"attributes":[{"id":"A172","pred":"chebi_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"},{"id":"A173","pred":"chebi_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A174","pred":"chebi_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A175","pred":"chebi_id","subj":"T175","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A176","pred":"chebi_id","subj":"T176","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A177","pred":"chebi_id","subj":"T177","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1186","span":{"begin":322,"end":325},"obj":"Gene"},{"id":"1187","span":{"begin":330,"end":333},"obj":"Gene"},{"id":"1208","span":{"begin":346,"end":347},"obj":"Gene"},{"id":"1209","span":{"begin":133,"end":134},"obj":"Gene"},{"id":"1222","span":{"begin":88,"end":98},"obj":"Species"}],"attributes":[{"id":"A1186","pred":"tao:has_database_id","subj":"1186","obj":"Gene:920"},{"id":"A1187","pred":"tao:has_database_id","subj":"1187","obj":"Gene:925"},{"id":"A1208","pred":"tao:has_database_id","subj":"1208","obj":"Gene:43740568"},{"id":"A1209","pred":"tao:has_database_id","subj":"1209","obj":"Gene:43740568"},{"id":"A1222","pred":"tao:has_database_id","subj":"1222","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms."}

{"project":"LitCovid-sentences","denotations":[{"id":"T198","span":{"begin":0,"end":462},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms."}