PMC:7200337 / 27856-28807
Annnotations
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32505227-26727464-46575297 | 154-158 | 26727464 | denotes | 2016 |
32505227-30770247-46575298 | 176-180 | 30770247 | denotes | 2019 |
32505227-21946417-46575299 | 387-391 | 21946417 | denotes | 2011 |
32505227-21623379-46575300 | 548-552 | 21623379 | denotes | 2011 |
32505227-30414858-46575301 | 719-723 | 30414858 | denotes | 2019 |
T62134 | 154-158 | 26727464 | denotes | 2016 |
T45258 | 176-180 | 30770247 | denotes | 2019 |
T84724 | 387-391 | 21946417 | denotes | 2011 |
T32079 | 548-552 | 21623379 | denotes | 2011 |
T18273 | 719-723 | 30414858 | denotes | 2019 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T276 | 131-135 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T277 | 226-230 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T278 | 334-344 | Body_part | denotes | epithelium | http://purl.org/sig/ont/fma/fma9639 |
T279 | 464-475 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
T280 | 483-487 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T281 | 604-624 | Body_part | denotes | alveolar macrophages | http://purl.org/sig/ont/fma/fma83023 |
T282 | 818-828 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
T283 | 829-840 | Body_part | denotes | compartment | http://purl.org/sig/ont/fma/fma76577 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T29 | 131-135 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T30 | 226-230 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T31 | 334-344 | Body_part | denotes | epithelium | http://purl.obolibrary.org/obo/UBERON_0000483 |
T32 | 483-487 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T186 | 68-76 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T187 | 79-88 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T188 | 250-269 | Disease | denotes | influenza infection | http://purl.obolibrary.org/obo/MONDO_0005812 |
T189 | 260-269 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T190 | 492-501 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T191 | 853-861 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T192 | 899-907 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T193 | 910-919 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T297 | 131-135 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T298 | 131-135 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T299 | 226-230 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T300 | 226-230 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T301 | 327-333 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
T302 | 334-344 | http://purl.obolibrary.org/obo/UBERON_0000483 | denotes | epithelium |
T303 | 483-487 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T304 | 483-487 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T305 | 510-516 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
T306 | 563-567 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
T307 | 640-641 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T308 | 642-644 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | M1 |
T309 | 642-644 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | M1 |
T310 | 679-680 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T311 | 891-895 | http://purl.obolibrary.org/obo/CL_0001065 | denotes | ILCs |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T130 | 349-355 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T131 | 422-424 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T133 | 642-644 | Chemical | denotes | M1 | http://purl.obolibrary.org/obo/CHEBI_51079|http://purl.obolibrary.org/obo/CHEBI_139019|http://purl.obolibrary.org/obo/CHEBI_140152|http://purl.obolibrary.org/obo/CHEBI_34826 |
T137 | 681-683 | Chemical | denotes | M2 | http://purl.obolibrary.org/obo/CHEBI_34827|http://purl.obolibrary.org/obo/CHEBI_51112 |
T139 | 746-748 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
905 | 286-298 | Gene | denotes | amphiregulin | Gene:11839 |
906 | 422-427 | Gene | denotes | IL-13 | Gene:3596 |
907 | 746-751 | Gene | denotes | IL-13 | Gene:3596 |
908 | 476-478 | Gene | denotes | to | Gene:6999 |
909 | 442-444 | Gene | denotes | to | Gene:6999 |
910 | 12-14 | Gene | denotes | to | Gene:6999 |
911 | 273-277 | Species | denotes | mice | Tax:10090 |
912 | 862-870 | Species | denotes | patients | Tax:9606 |
913 | 250-259 | Species | denotes | influenza | Tax:11520 |
914 | 492-501 | Species | denotes | influenza | Tax:11520 |
915 | 349-355 | Chemical | denotes | oxygen | MESH:D010100 |
916 | 68-88 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
917 | 260-269 | Disease | denotes | infection | MESH:D007239 |
918 | 853-861 | Disease | denotes | COVID-19 | MESH:C000657245 |
919 | 899-919 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T155 | 0-89 | Sentence | denotes | No studies, to date, have reported ILC1, ILC2, or ILC3 functions in SARS-CoV-2 infection. |
T156 | 90-182 | Sentence | denotes | All three subsets are present in healthy lung (De Grove et al., 2016, Yudanin et al., 2019). |
T157 | 183-393 | Sentence | denotes | ILC2s are essential for the improvement of lung function following influenza infection in mice through amphiregulin-mediated restoration of the airway epithelium and oxygen saturation (Monticelli et al., 2011). |
T158 | 394-554 | Sentence | denotes | However, ILC2s also produce IL-13, contributing to the recruitment of macrophages to the lung and influenza-induced airway hyperreactivity (Chang et al., 2011). |
T159 | 555-725 | Sentence | denotes | Indeed, ILCs are involved in the polarization of alveolar macrophages, either toward a M1-like phenotype (ILC1 and ILC3) or a M2-like phenotype (ILC2) (Kim et al., 2019). |
T160 | 726-951 | Sentence | denotes | Given the increased IL-13 concentrations (Huang et al., 2020b) and the dysregulation of the macrophage compartment observed in COVID-19 patients, the role played by ILCs in SARS-CoV-2 infection warrants further investigation. |