
PMC:7200337 / 17551-18455
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T105 | 6-10 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
T106 | 51-60 | Body_part | denotes | epithelia | http://purl.org/sig/ont/fma/fma9639 |
T107 | 118-129 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
T108 | 160-169 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
T109 | 182-194 | Body_part | denotes | granulocytes | http://purl.org/sig/ont/fma/fma62854 |
T110 | 199-210 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T111 | 266-275 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
T112 | 335-343 | Body_part | denotes | monocyte | http://purl.org/sig/ont/fma/fma62864 |
T113 | 352-363 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
T114 | 510-522 | Body_part | denotes | neutrophilic | http://purl.org/sig/ont/fma/fma62860 |
T115 | 589-602 | Body_part | denotes | myeloid cells | http://purl.org/sig/ont/fma/fma70339 |
T116 | 597-602 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T117 | 680-688 | Body_part | denotes | Monocyte | http://purl.org/sig/ont/fma/fma62864 |
T118 | 723-731 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
T119 | 726-731 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T120 | 737-742 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
T121 | 806-814 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
T122 | 809-814 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T123 | 871-876 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T124 | 894-903 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T10 | 51-60 | Body_part | denotes | epithelia | http://purl.obolibrary.org/obo/UBERON_0000483 |
T11 | 737-742 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T121 | 458-461 | Disease | denotes | CRS | http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361 |
T123 | 564-572 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T124 | 857-861 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11301 | 160-169 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
T3621 | 252-253 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | ɑ |
T320 | 266-275 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
T78868 | 335-343 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocyte |
T1737 | 597-602 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T84467 | 680-688 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | Monocyte |
T47301 | 706-708 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T48426 | 723-731 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
T52652 | 737-742 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
T31933 | 737-742 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
T14324 | 806-814 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
T89373 | 871-876 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T45576 | 894-903 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T74 | 0-2 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T76 | 6-8 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T78 | 239-241 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
T80 | 697-702 | Chemical | denotes | CXCL9 | http://purl.obolibrary.org/obo/CHEBI_138154 |
T81 | 778-787 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T78 | 477-498 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
508 | 0-4 | Gene | denotes | IL-6 | Gene:3569 |
509 | 6-11 | Gene | denotes | IL-1β | Gene:3552 |
510 | 239-243 | Gene | denotes | IL-6 | Gene:3569 |
511 | 248-253 | Gene | denotes | TNF-ɑ | Gene:7124 |
512 | 697-708 | Gene | denotes | CXCL9/10/11 | Gene:4283 |
513 | 32-40 | Disease | denotes | infected | MESH:D007239 |
514 | 376-389 | Disease | denotes | dysfunctional | MESH:D009461 |
515 | 510-550 | Disease | denotes | neutrophilic NETosis and microthrombosis | MESH:C564275 |
516 | 564-572 | Disease | denotes | COVID-19 | MESH:C000657245 |
517 | 857-870 | Disease | denotes | SARS-infected | MESH:D045169 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T98 | 0-228 | Sentence | denotes | IL-6, IL-1β, and IFN-I/III from infected pulmonary epithelia can induce inflammatory programs in resident (alternate) macrophages while recruiting inflammatory monocytes, as well as granulocytes and lymphocytes from circulation. |
T99 | 229-321 | Sentence | denotes | Sustained IL-6 and TNF-ɑ by incoming monocytes can drive several hyperinflammation cascades. |
T100 | 322-444 | Sentence | denotes | Inflammatory monocyte-derived macrophages can amplify dysfunctional responses in various ways (listed in top-left corner). |
T101 | 445-582 | Sentence | denotes | The systemic CRS- and sHLH-like inflammatory response can induce neutrophilic NETosis and microthrombosis, aggravating COVID-19 severity. |
T102 | 583-679 | Sentence | denotes | Other myeloid cells, such as pDCs, are purported to have an IFN-dependent role in viral control. |
T103 | 680-743 | Sentence | denotes | Monocyte-derived CXCL9/10/11 might recruit NK cells from blood. |
T104 | 744-904 | Sentence | denotes | Preliminary data suggest that the antiviral function of these NK cells might be regulated through crosstalk with SARS-infected cells and inflammatory monocytes. |