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PMC:7200337 JSONTXT

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2_test

Id Subject Object Predicate Lexical cue
32505227-27344959-46575204 2721-2725 27344959 denotes 2016
32505227-32109011-46575205 2803-2807 32109011 denotes 2020
32505227-26867177-46575206 5161-5165 26867177 denotes 2016
32505227-24753610-46575208 5963-5967 24753610 denotes 2014
32505227-29263263-46575209 5982-5986 29263263 denotes 2018
32505227-23029269-46575210 6289-6293 23029269 denotes 2012
32505227-20020050-46575211 6312-6316 20020050 denotes 2009
32505227-19380580-46575212 6330-6334 19380580 denotes 2009
32505227-17715225-46575213 6353-6357 17715225 denotes 2007
32505227-20421945-46575214 7620-7624 20421945 denotes 2010
32505227-19208801-46575215 7639-7643 19208801 denotes 2009
32505227-28484023-46575216 7658-7662 28484023 denotes 2017
32505227-32198201-46575217 7681-7685 32198201 denotes 2020
32505227-15140959-46575218 7702-7706 15140959 denotes 2004
32505227-18798692-46575219 7723-7727 18798692 denotes 2008
32505227-18798692-46575220 7865-7869 18798692 denotes 2008
32505227-20421945-46575221 8018-8022 20421945 denotes 2010
32505227-19208801-46575222 8037-8041 19208801 denotes 2009
32505227-15140959-46575223 8058-8062 15140959 denotes 2004
32505227-28484023-46575224 8334-8338 28484023 denotes 2017
32505227-32198201-46575225 8357-8361 32198201 denotes 2020
32505227-28148787-46575226 8503-8507 28148787 denotes 2017
32505227-27783669-46575227 8620-8624 27783669 denotes 2016
32505227-24027320-46575228 8684-8688 24027320 denotes 2013
32505227-24522921-46575229 8702-8706 24522921 denotes 2014
32505227-27025250-46575230 8804-8808 27025250 denotes 2016
32505227-22312431-46575231 8999-9003 22312431 denotes 2012
32505227-25135833-46575232 9763-9767 25135833 denotes 2014
32505227-19380580-46575233 10025-10029 19380580 denotes 2009
32505227-26631542-46575234 10069-10073 26631542 denotes 2015
32505227-17761676-46575235 10208-10212 17761676 denotes 2007
32505227-17108024-46575236 10239-10243 17108024 denotes 2007
32505227-19369340-46575237 10333-10337 19369340 denotes 2009
32505227-29370303-46575238 10383-10387 29370303 denotes 2018
32505227-19838190-46575240 10478-10482 19838190 denotes 2009
32505227-26311885-46575241 10522-10526 26311885 denotes 2015
32505227-20020050-46575242 10954-10958 20020050 denotes 2009
32505227-17715225-46575243 11019-11023 17715225 denotes 2007
32505227-17596301-46575244 11097-11101 17596301 denotes 2007
32505227-17108024-46575245 11128-11132 17108024 denotes 2007
32505227-26867177-46575246 11878-11882 26867177 denotes 2016
32505227-26867177-46575247 12047-12051 26867177 denotes 2016
32505227-30761102-46575248 12442-12446 30761102 denotes 2019
32505227-26331680-46575249 12469-12473 26331680 denotes 2015
32505227-31231549-46575250 12487-12491 31231549 denotes 2019
32505227-31034780-46575251 12505-12509 31034780 denotes 2019
32505227-23549447-46575252 13450-13454 23549447 denotes 2013
32505227-32192578-46575253 13696-13700 32192578 denotes 2020
32505227-19851468-46575254 15849-15853 19851468 denotes 2009
32505227-23015710-46575255 16001-16005 23015710 denotes 2012
32505227-26867177-46575256 16313-16317 26867177 denotes 2016
32505227-16985170-46575257 16525-16529 16985170 denotes 2007
32505227-22345460-46575259 17223-17227 22345460 denotes 2012
32505227-31662487-46575260 19004-19008 31662487 denotes 2019
32505227-16322745-46575261 19114-19118 16322745 denotes 2005
32505227-24065148-46575262 19133-19137 24065148 denotes 2014
32505227-32192578-46575263 19581-19585 32192578 denotes 2020
32505227-32289152-46575264 19989-19993 32289152 denotes 2020
32505227-27381687-46575265 20010-20014 27381687 denotes 2016
32505227-30761102-46575266 20223-20227 30761102 denotes 2019
32505227-31231549-46575267 20241-20245 31231549 denotes 2019
32505227-30050058-46575268 20454-20458 30050058 denotes 2019
32505227-28553293-46575269 20797-20801 28553293 denotes 2017
32505227-31140942-46575270 20825-20829 31140942 denotes 2019
32505227-32302401-46575271 20980-20984 32302401 denotes 2020
32505227-30142344-46575272 21679-21683 30142344 denotes 2018
32505227-26472762-46575274 22378-22382 26472762 denotes 2015
32505227-27670241-46575275 22402-22406 27670241 denotes 2017
32505227-29719539-46575276 22507-22511 29719539 denotes 2018
32505227-11905813-46575277 23253-23257 11905813 denotes 2001
32505227-17312110-46575278 23274-23278 17312110 denotes 2007
32505227-26919106-46575279 23299-23303 26919106 denotes 2016
32505227-22615821-46575280 23321-23325 22615821 denotes 2012
32505227-31316510-46575281 24039-24043 31316510 denotes 2019
32505227-19587043-46575283 24936-24940 19587043 denotes 2009
32505227-27670241-46575284 25416-25420 27670241 denotes 2017
32505227-30778167-46575285 25631-25635 30778167 denotes 2019
32505227-15080302-46575286 25790-25794 15080302 denotes 2004
32505227-9486650-46575289 26232-26236 9486650 denotes 1998
32505227-9034158-46575290 26253-26257 9034158 denotes 1997
32505227-29302013-46575291 26359-26363 29302013 denotes 2018
32505227-26251193-46575293 27058-27062 26251193 denotes 2015
32505227-19559672-46575295 27392-27396 19559672 denotes 2009
32505227-30524877-46575296 27455-27459 30524877 denotes 2017
32505227-26727464-46575297 28010-28014 26727464 denotes 2016
32505227-30770247-46575298 28032-28036 30770247 denotes 2019
32505227-21946417-46575299 28243-28247 21946417 denotes 2011
32505227-21623379-46575300 28404-28408 21623379 denotes 2011
32505227-30414858-46575301 28575-28579 30414858 denotes 2019
32505227-16095942-46575303 29653-29657 16095942 denotes 2005
32505227-32284614-46575310 30440-30444 32284614 denotes 2020
32505227-26203058-46575311 30669-30673 26203058 denotes 2016
32505227-16868248-46575314 32479-32483 16868248 denotes 2006
32505227-16525420-46575315 32499-32503 16525420 denotes 2006
32505227-18832706-46575317 34051-34055 18832706 denotes 2008
32505227-26954467-46575318 34307-34311 26954467 denotes 2016
32505227-21576510-46575319 34326-34330 21576510 denotes 2011
32505227-18832706-46575320 34593-34597 18832706 denotes 2008
32505227-18832706-46575321 35078-35082 18832706 denotes 2008
32505227-27773482-46575322 36446-36450 27773482 denotes 2016
32505227-16164833-46575323 37700-37704 16164833 denotes 2005
32505227-30327490-46575324 39218-39222 30327490 denotes 2019
32505227-30564234-46575325 39687-39691 30564234 denotes 2018
32505227-23064104-46575326 39707-39711 23064104 denotes 2013
32505227-32284614-46575327 40269-40273 32284614 denotes 2020
32505227-32284614-46575329 40463-40467 32284614 denotes 2020
32505227-18832706-46575330 40581-40585 18832706 denotes 2008
32505227-29654146-46575331 40978-40982 29654146 denotes 2018
32505227-18832706-46575337 42652-42656 18832706 denotes 2008
32505227-32284614-46575338 43620-43624 32284614 denotes 2020
32505227-15606632-46575340 44472-44476 15606632 denotes 2004
32505227-32213337-46575341 44952-44956 32213337 denotes 2020
32505227-32213337-46575342 45278-45282 32213337 denotes 2020
32505227-32284614-46575343 48346-48350 32284614 denotes 2020
32505227-2170159-46575344 49248-49252 2170159 denotes 1990
32505227-6319590-46575345 49260-49264 6319590 denotes 1984
32505227-17855683-46575346 49525-49529 17855683 denotes 2007
32505227-16479513-46575347 49543-49547 16479513 denotes 2006
32505227-27332149-46575348 49930-49934 27332149 denotes 2016
32505227-15247913-46575349 50454-50458 15247913 denotes 2004
32505227-21576510-46575350 50620-50624 21576510 denotes 2011
32505227-21576510-46575351 50754-50758 21576510 denotes 2011
32505227-16299724-46575353 52033-52037 16299724 denotes 2006
32505227-26497532-46575354 52449-52453 26497532 denotes 2015
32505227-24885320-46575355 52819-52823 24885320 denotes 2014
32505227-32259480-46575357 54093-54097 32259480 denotes 2020
32505227-12692541-46575358 55302-55306 12692541 denotes 2003
32505227-17570115-46575359 55849-55853 17570115 denotes 2007
32505227-21958371-46575360 55868-55872 21958371 denotes 2011
32505227-21745520-46575361 55887-55891 21745520 denotes 2011
32505227-32265220-46575366 58870-58874 32265220 denotes 2020
32505227-32265220-46575368 59404-59408 32265220 denotes 2020
32505227-32265220-46575369 59716-59720 32265220 denotes 2020
32505227-32265220-46575370 60027-60031 32265220 denotes 2020
32505227-32265220-46575378 65930-65934 32265220 denotes 2020
32505227-32325026-46575379 66516-66520 32325026 denotes 2020
32505227-22363001-46575382 69695-69699 22363001 denotes 2012
32505227-28659436-46575383 71341-71345 28659436 denotes 2017
32505227-29511076-46575385 73491-73495 29511076 denotes 2018
32505227-28659436-46575386 73628-73632 28659436 denotes 2017
32505227-32054787-46575387 73649-73653 32054787 denotes 2020
32505227-30724789-46575388 75698-75702 30724789 denotes 2019
32505227-14985565-46575389 76221-76225 14985565 denotes 2004
32505227-14592603-46575390 79003-79007 14592603 denotes 2003
32505227-15351731-46575391 79053-79057 15351731 denotes 2004
32505227-16115318-46575392 79075-79079 16115318 denotes 2005
32505227-18753338-46575393 79360-79364 18753338 denotes 2008
32505227-26206937-46575394 79377-79381 26206937 denotes 2015
32505227-32034323-46575395 79409-79413 32034323 denotes 2020
32505227-32272008-46575401 87048-87052 32272008 denotes 2020
32505227-32122468-46575402 87109-87113 32122468 denotes 2020
32505227-29033947-46575403 88256-88260 29033947 denotes 2017
32505227-32289152-46575404 88287-88291 32289152 denotes 2020
32505227-17537853-46575405 88689-88693 17537853 denotes 2007
32505227-31925415-46575406 88839-88843 31925415 denotes 2020
32505227-31924756-46575407 88969-88973 31924756 denotes 2020
32505227-26867177-46575408 89399-89403 26867177 denotes 2016
32505227-16482545-46575409 89424-89428 16482545 denotes 2006
32505227-32303591-46575410 89764-89768 32303591 denotes 2020
32505227-15860669-46575411 90973-90977 15860669 denotes 2005
32505227-32303591-46575412 90995-90999 32303591 denotes 2020
32505227-15919935-46575413 91257-91261 15919935 denotes 2005
32505227-17052299-46575414 91277-91281 17052299 denotes 2006
32505227-15888207-46575415 91337-91341 15888207 denotes 2005
32505227-15030519-46575416 91356-91360 15030519 denotes 2004
32505227-32303591-46575417 91613-91617 32303591 denotes 2020
32505227-21047436-46575418 94331-94335 21047436 denotes 2010
32505227-16318725-46575419 94348-94352 16318725 denotes 2005
32505227-15220038-46575420 94373-94377 15220038 denotes 2004
32505227-14983044-46575421 94410-94414 14983044 denotes 2004
32505227-17620608-46575422 94428-94432 17620608 denotes 2007
32505227-26404138-46575423 94462-94466 26404138 denotes 2015
32505227-31130102-46575424 94480-94484 31130102 denotes 2019
32505227-25456101-46575425 94499-94503 25456101 denotes 2015
32505227-32155444-46575426 94855-94859 32155444 denotes 2020
32505227-32416259-46575428 97214-97218 32416259 denotes 2020
32505227-32416259-46575430 97704-97708 32416259 denotes 2020
32505227-32155444-46575431 98122-98126 32155444 denotes 2020
32505227-31774948-46575433 99227-99231 31774948 denotes 2019
32505227-16940336-46575435 100490-100494 16940336 denotes 2006
32505227-21248066-46575436 100526-100530 21248066 denotes 2011
32505227-27405596-46575437 100563-100567 27405596 denotes 2016
32505227-32281317-46575438 100962-100966 32281317 denotes 2020
32505227-32253318-46575439 100981-100985 32253318 denotes 2020
32505227-32217555-46575440 101576-101580 32217555 denotes 2020
32505227-16940336-46575442 101845-101849 16940336 denotes 2006
32505227-32253318-46575443 102549-102553 32253318 denotes 2020
32505227-32281317-46575444 103186-103190 32281317 denotes 2020
32505227-12531323-46575445 103946-103950 12531323 denotes 2003
32505227-19198616-46575446 104873-104877 19198616 denotes 2009
32505227-30058403-46575447 104911-104915 30058403 denotes 2018
32505227-32155444-46575448 104978-104982 32155444 denotes 2020
32505227-19198616-46575449 105152-105156 19198616 denotes 2009
32505227-15878679-46575450 105406-105410 15878679 denotes 2005
32505227-15857975-46575451 105424-105428 15857975 denotes 2005
32505227-18832706-46575453 106077-106081 18832706 denotes 2008
32505227-26954467-46575454 106094-106098 26954467 denotes 2016
32505227-32022276-46575455 106983-106987 32022276 denotes 2020
32505227-32183941-46575456 107051-107055 32183941 denotes 2020
32505227-32132669-46575457 107091-107095 32132669 denotes 2020
32505227-32183941-46575458 107323-107327 32183941 denotes 2020
32505227-18018769-46575459 107570-107574 18018769 denotes 2007
32505227-18824060-46575460 107591-107595 18824060 denotes 2008
32505227-31351922-46575461 107615-107619 31351922 denotes 2019
32505227-32249203-46575462 108183-108187 32249203 denotes 2020
32505227-29456015-46575463 109155-109159 29456015 denotes 2018
32505227-28151488-46575464 109181-109185 28151488 denotes 2017
32505227-31351922-46575465 109479-109483 31351922 denotes 2019
32505227-26386540-46575466 109507-109511 26386540 denotes 2015
32505227-25817373-46575467 109618-109622 25817373 denotes 2015
32505227-28017399-46575468 109636-109640 28017399 denotes 2017
32505227-28579232-46575469 109791-109795 28579232 denotes 2017
32505227-24374965-46575470 109820-109824 24374965 denotes 2014
32505227-32269218-46575471 110314-110318 32269218 denotes 2020
32505227-29242543-46575472 111999-112003 29242543 denotes 2018
32505227-32273594-46575473 112223-112227 32273594 denotes 2020
32505227-32092539-46575474 112236-112240 32092539 denotes 2020
32505227-32273591-46575475 112751-112755 32273591 denotes 2020
T36575 2721-2725 27344959 denotes 2016
T48054 2803-2807 32109011 denotes 2020
T37023 5161-5165 26867177 denotes 2016
T35918 5963-5967 24753610 denotes 2014
T29286 5982-5986 29263263 denotes 2018
T72435 6289-6293 23029269 denotes 2012
T21841 6312-6316 20020050 denotes 2009
T20061 6330-6334 19380580 denotes 2009
T44255 6353-6357 17715225 denotes 2007
T17359 7620-7624 20421945 denotes 2010
T71054 7639-7643 19208801 denotes 2009
T24761 7658-7662 28484023 denotes 2017
T39611 7681-7685 32198201 denotes 2020
T93249 7702-7706 15140959 denotes 2004
T76836 7723-7727 18798692 denotes 2008
T62656 7865-7869 18798692 denotes 2008
T84062 8018-8022 20421945 denotes 2010
T40525 8037-8041 19208801 denotes 2009
T81131 8058-8062 15140959 denotes 2004
T21708 8334-8338 28484023 denotes 2017
T46007 8357-8361 32198201 denotes 2020
T74995 8503-8507 28148787 denotes 2017
T31213 8620-8624 27783669 denotes 2016
T40397 8684-8688 24027320 denotes 2013
T35216 8702-8706 24522921 denotes 2014
T20105 8804-8808 27025250 denotes 2016
T99345 8999-9003 22312431 denotes 2012
T99744 9763-9767 25135833 denotes 2014
T89021 10025-10029 19380580 denotes 2009
T58194 10069-10073 26631542 denotes 2015
T64611 10208-10212 17761676 denotes 2007
T46471 10239-10243 17108024 denotes 2007
T33023 10333-10337 19369340 denotes 2009
T71391 10383-10387 29370303 denotes 2018
T25270 10478-10482 19838190 denotes 2009
T42335 10522-10526 26311885 denotes 2015
T49884 10954-10958 20020050 denotes 2009
T91546 11019-11023 17715225 denotes 2007
T48406 11097-11101 17596301 denotes 2007
T53979 11128-11132 17108024 denotes 2007
T64773 11878-11882 26867177 denotes 2016
T66903 12047-12051 26867177 denotes 2016
T63051 12442-12446 30761102 denotes 2019
T37267 12469-12473 26331680 denotes 2015
T42183 12487-12491 31231549 denotes 2019
T82803 12505-12509 31034780 denotes 2019
T24846 13450-13454 23549447 denotes 2013
T89425 13696-13700 32192578 denotes 2020
T96613 15849-15853 19851468 denotes 2009
T13230 16001-16005 23015710 denotes 2012
T82690 16313-16317 26867177 denotes 2016
T43572 16525-16529 16985170 denotes 2007
T36838 17223-17227 22345460 denotes 2012
T48811 19004-19008 31662487 denotes 2019
T21223 19114-19118 16322745 denotes 2005
T70263 19133-19137 24065148 denotes 2014
T29085 19581-19585 32192578 denotes 2020
T27289 19989-19993 32289152 denotes 2020
T78268 20010-20014 27381687 denotes 2016
T82756 20223-20227 30761102 denotes 2019
T28569 20241-20245 31231549 denotes 2019
T79483 20454-20458 30050058 denotes 2019
T5101 20797-20801 28553293 denotes 2017
T79329 20825-20829 31140942 denotes 2019
T2404 20980-20984 32302401 denotes 2020
T67844 58870-58874 32265220 denotes 2020
T81666 59404-59408 32265220 denotes 2020
T24032 59716-59720 32265220 denotes 2020
T75549 60027-60031 32265220 denotes 2020
T74386 65930-65934 32265220 denotes 2020
T28986 21679-21683 30142344 denotes 2018
T72451 22378-22382 26472762 denotes 2015
T78562 66516-66520 32325026 denotes 2020
T73641 22402-22406 27670241 denotes 2017
T77645 69695-69699 22363001 denotes 2012
T99238 22507-22511 29719539 denotes 2018
T38685 23253-23257 11905813 denotes 2001
T24626 71341-71345 28659436 denotes 2017
T58214 23274-23278 17312110 denotes 2007
T1045 23299-23303 26919106 denotes 2016
T66152 73491-73495 29511076 denotes 2018
T956 73628-73632 28659436 denotes 2017
T59596 23321-23325 22615821 denotes 2012
T22463 24039-24043 31316510 denotes 2019
T69970 24936-24940 19587043 denotes 2009
T60836 25416-25420 27670241 denotes 2017
T91375 25631-25635 30778167 denotes 2019
T21517 25790-25794 15080302 denotes 2004
T58402 26232-26236 9486650 denotes 1998
T11232 26253-26257 9034158 denotes 1997
T15390 26359-26363 29302013 denotes 2018
T84673 27058-27062 26251193 denotes 2015
T83308 27392-27396 19559672 denotes 2009
T78837 27455-27459 30524877 denotes 2017
T62134 28010-28014 26727464 denotes 2016
T45258 28032-28036 30770247 denotes 2019
T84724 28243-28247 21946417 denotes 2011
T32079 28404-28408 21623379 denotes 2011
T18273 28575-28579 30414858 denotes 2019
T99166 29653-29657 16095942 denotes 2005
T6822 30440-30444 32284614 denotes 2020
T67792 30669-30673 26203058 denotes 2016
T2441 32479-32483 16868248 denotes 2006
T35567 32499-32503 16525420 denotes 2006
T14716 34051-34055 18832706 denotes 2008
T41595 34307-34311 26954467 denotes 2016
T75007 34326-34330 21576510 denotes 2011
T11313 34593-34597 18832706 denotes 2008
T83719 35078-35082 18832706 denotes 2008
T69407 36446-36450 27773482 denotes 2016
T96438 37700-37704 16164833 denotes 2005
T1317 39218-39222 30327490 denotes 2019
T1331 39687-39691 30564234 denotes 2018
T77685 39707-39711 23064104 denotes 2013
T4570 40269-40273 32284614 denotes 2020
T63291 40463-40467 32284614 denotes 2020
T22882 40581-40585 18832706 denotes 2008
T81493 40978-40982 29654146 denotes 2018
T22604 42652-42656 18832706 denotes 2008
T87043 43620-43624 32284614 denotes 2020
T91196 44472-44476 15606632 denotes 2004
T89937 44952-44956 32213337 denotes 2020
T38281 45278-45282 32213337 denotes 2020
T8258 48346-48350 32284614 denotes 2020
T25623 49248-49252 2170159 denotes 1990
T92263 49260-49264 6319590 denotes 1984
T20220 49525-49529 17855683 denotes 2007
T91627 49543-49547 16479513 denotes 2006
T90393 49930-49934 27332149 denotes 2016
T90020 50454-50458 15247913 denotes 2004
T76591 50620-50624 21576510 denotes 2011
T92702 50754-50758 21576510 denotes 2011
T99561 52033-52037 16299724 denotes 2006
T95047 52449-52453 26497532 denotes 2015
T7910 52819-52823 24885320 denotes 2014
T18004 54093-54097 32259480 denotes 2020
T65249 55302-55306 12692541 denotes 2003
T5000 55849-55853 17570115 denotes 2007
T67612 55868-55872 21958371 denotes 2011
T29548 55887-55891 21745520 denotes 2011
T31132 73649-73653 32054787 denotes 2020
T127 75698-75702 30724789 denotes 2019
T86887 76221-76225 14985565 denotes 2004
T12810 79003-79007 14592603 denotes 2003
T15719 79053-79057 15351731 denotes 2004
T7708 79075-79079 16115318 denotes 2005
T13584 79360-79364 18753338 denotes 2008
T382 79377-79381 26206937 denotes 2015
T25901 79409-79413 32034323 denotes 2020
T29195 87048-87052 32272008 denotes 2020
T83732 87109-87113 32122468 denotes 2020
T8380 88256-88260 29033947 denotes 2017
T20213 88287-88291 32289152 denotes 2020
T67437 88689-88693 17537853 denotes 2007
T59534 88839-88843 31925415 denotes 2020
T50703 88969-88973 31924756 denotes 2020
T33795 89399-89403 26867177 denotes 2016
T23514 89424-89428 16482545 denotes 2006
T3033 89764-89768 32303591 denotes 2020
T3486 90973-90977 15860669 denotes 2005
T86573 90995-90999 32303591 denotes 2020
T99556 91257-91261 15919935 denotes 2005
T42792 91277-91281 17052299 denotes 2006
T45143 91337-91341 15888207 denotes 2005
T73456 91356-91360 15030519 denotes 2004
T66898 91613-91617 32303591 denotes 2020
T46722 94331-94335 21047436 denotes 2010
T13757 94348-94352 16318725 denotes 2005
T32153 94373-94377 15220038 denotes 2004
T40642 94410-94414 14983044 denotes 2004
T65482 94428-94432 17620608 denotes 2007
T96040 94462-94466 26404138 denotes 2015
T25280 94480-94484 31130102 denotes 2019
T65647 94499-94503 25456101 denotes 2015
T4350 94855-94859 32155444 denotes 2020
T94852 97214-97218 32416259 denotes 2020
T64637 97704-97708 32416259 denotes 2020
T33611 98122-98126 32155444 denotes 2020
T74065 99227-99231 31774948 denotes 2019
T69935 100490-100494 16940336 denotes 2006
T78315 100526-100530 21248066 denotes 2011
T33973 100563-100567 27405596 denotes 2016
T25859 100962-100966 32281317 denotes 2020
T29360 100981-100985 32253318 denotes 2020
T16803 101576-101580 32217555 denotes 2020
T204 101845-101849 16940336 denotes 2006
T98365 102549-102553 32253318 denotes 2020
T99026 103186-103190 32281317 denotes 2020
T40770 103946-103950 12531323 denotes 2003
T46174 104873-104877 19198616 denotes 2009
T50934 104911-104915 30058403 denotes 2018
T45442 104978-104982 32155444 denotes 2020
T86111 105152-105156 19198616 denotes 2009
T47158 105406-105410 15878679 denotes 2005
T45218 105424-105428 15857975 denotes 2005
T57864 106077-106081 18832706 denotes 2008
T56463 106094-106098 26954467 denotes 2016
T35612 106983-106987 32022276 denotes 2020
T23493 107051-107055 32183941 denotes 2020
T15418 107091-107095 32132669 denotes 2020
T66082 107323-107327 32183941 denotes 2020
T97524 107570-107574 18018769 denotes 2007
T59957 107591-107595 18824060 denotes 2008
T65299 107615-107619 31351922 denotes 2019
T17822 108183-108187 32249203 denotes 2020
T14358 109155-109159 29456015 denotes 2018
T62936 109181-109185 28151488 denotes 2017
T51102 109479-109483 31351922 denotes 2019
T13962 109507-109511 26386540 denotes 2015
T50496 109618-109622 25817373 denotes 2015
T64340 109636-109640 28017399 denotes 2017
T45793 109791-109795 28579232 denotes 2017
T6171 109820-109824 24374965 denotes 2014
T33073 110314-110318 32269218 denotes 2020
T10568 111999-112003 29242543 denotes 2018
T15705 112223-112227 32273594 denotes 2020
T77217 112236-112240 32092539 denotes 2020
T35247 112751-112755 32273591 denotes 2020

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 100163-100169 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T2 100754-100760 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T3 100771-100779 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T4 101964-101970 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T5 102088-102094 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T6 102263-102267 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T7 102554-102559 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T8 102585-102595 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T9 102742-102750 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T10 102938-102943 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T11 103210-103215 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T12 104130-104137 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T13 104495-104502 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T14 104561-104568 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T15 104695-104702 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 104991-104998 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T17 105117-105121 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T18 105276-105283 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T19 105314-105322 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T20 105671-105675 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T21 105699-105706 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T22 105754-105758 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T23 105814-105819 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T24 105858-105866 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T25 105882-105886 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T26 105963-105968 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T27 106040-106045 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T28 106059-106064 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T29 106126-106130 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T30 106367-106374 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T31 106464-106471 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T32 106493-106501 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T33 106562-106567 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T34 106743-106747 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T35 106776-106784 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T36 106854-106862 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T37 107110-107117 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T38 107163-107170 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T39 107198-107206 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T40 107228-107232 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T41 107458-107465 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T42 108141-108148 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T43 108411-108418 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T44 109069-109073 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T45 109096-109100 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T46 109119-109126 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T47 109237-109241 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T48 109277-109280 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T49 109390-109393 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T50 109420-109427 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T51 109575-109582 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T52 109736-109743 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T53 109859-109874 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T54 109869-109874 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T55 110243-110250 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T56 110460-110467 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T57 110561-110585 Body_part denotes antigen-presenting cells http://purl.org/sig/ont/fma/fma273565
T58 110580-110585 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T59 110731-110736 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T60 111823-111827 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T61 112065-112073 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T62 114930-114934 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T63 114939-114946 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T64 114942-114946 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T43388 2220-2224 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T61661 2449-2457 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T36595 4327-4330 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T86860 4476-4479 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T55110 4508-4511 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T23503 4524-4533 Body_part denotes cytosolic http://purl.org/sig/ont/fma/fma66836
T32099 4584-4593 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T31716 4698-4707 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T67799 4819-4828 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T69261 4895-4908 Body_part denotes interleukin-1 http://purl.org/sig/ont/fma/fma86583
T38358 4910-4914 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T79985 5003-5008 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T1916 5547-5557 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T32659 5645-5652 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T57686 5776-5784 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T27355 6042-6051 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T45987 6480-6484 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T57688 6510-6515 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T89729 6865-6873 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T35567 7372-7380 Body_part denotes endosome http://purl.org/sig/ont/fma/fma67180
T82904 7413-7420 Body_part denotes cytosol http://purl.org/sig/ont/fma/fma66836
T68353 7787-7799 Body_part denotes compartments http://purl.org/sig/ont/fma/fma76577
T90733 7891-7894 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T61076 7967-7975 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T58157 8089-8093 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T95730 8447-8454 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T1825 8942-8945 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T62070 9342-9351 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T34871 9438-9446 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T98576 9511-9519 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T56607 9957-9964 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T85573 10082-10090 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T13179 10277-10285 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T76049 10697-10705 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T41999 10829-10837 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T89236 12141-12150 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639
T67531 12387-12395 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T82844 12536-12540 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T26270 12847-12855 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T16244 13173-13186 Body_part denotes Myeloid Cells http://purl.org/sig/ont/fma/fma70339
T93727 13181-13186 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T94725 13267-13280 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T23806 13275-13280 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T8222 13336-13351 Body_part denotes dendritic cells http://purl.org/sig/ont/fma/fma273565
T63225 13346-13351 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T6508 13360-13368 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T17150 13419-13430 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T68174 13467-13471 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T61380 13633-13641 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T93377 13769-13803 Body_part denotes peripheral blood mononuclear cells http://purl.org/sig/ont/fma/fma86713
T49574 13798-13803 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T53773 13882-13893 Body_part denotes granulocyte http://purl.org/sig/ont/fma/fma62854
T29850 13894-13904 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T58554 13935-13938 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T62019 13968-13973 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T46660 13983-13986 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T69621 14005-14014 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T58770 14121-14125 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T63962 14177-14181 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T51981 14184-14193 Body_part denotes monocytic http://purl.org/sig/ont/fma/fma62864
T80984 14271-14278 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T53661 14353-14357 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T33309 14427-14432 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T65535 14483-14487 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T65 14668-14675 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T66 14766-14774 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T67 14783-14794 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T68 14813-14819 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T69 14840-14860 Body_part denotes alveolar macrophages http://purl.org/sig/ont/fma/fma83023
T70 14959-14967 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T71 15027-15035 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T72 15131-15152 Body_part denotes mononuclear phagocyte http://purl.org/sig/ont/fma/fma273563
T73 15154-15157 Body_part denotes MNP http://purl.org/sig/ont/fma/fma273563
T74 15264-15269 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T75 15289-15294 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T76 15299-15306 Body_part denotes kidneys http://purl.org/sig/ont/fma/fma7203
T77 15348-15361 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T78 15356-15361 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T79 15365-15371 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T80 15576-15588 Body_part denotes myeloid cell http://purl.org/sig/ont/fma/fma70339
T81 15584-15588 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T82 15819-15823 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T83 15894-15905 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T84 16127-16136 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T85 16137-16148 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T86 16157-16161 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T87 16162-16170 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T88 16175-16184 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T89 16243-16247 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T90 16672-16680 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T91 16726-16737 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T92 16742-16751 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T93 16772-16783 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T94 16791-16799 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T95 16997-17013 Body_part denotes immunoglobulin G http://purl.org/sig/ont/fma/fma62872
T96 17015-17018 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T97 17051-17055 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T98 17088-17108 Body_part denotes alveolar macrophages http://purl.org/sig/ont/fma/fma83023
T99 17182-17190 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T100 17281-17289 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T101 17404-17416 Body_part denotes Myeloid Cell http://purl.org/sig/ont/fma/fma70339
T102 17412-17416 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T103 17440-17447 Body_part denotes NK Cell http://purl.org/sig/ont/fma/fma63147
T104 17443-17447 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T105 17557-17561 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T106 17602-17611 Body_part denotes epithelia http://purl.org/sig/ont/fma/fma9639
T107 17669-17680 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T108 17711-17720 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T109 17733-17745 Body_part denotes granulocytes http://purl.org/sig/ont/fma/fma62854
T110 17750-17761 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T111 17817-17826 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T112 17886-17894 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T113 17903-17914 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T114 18061-18073 Body_part denotes neutrophilic http://purl.org/sig/ont/fma/fma62860
T115 18140-18153 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T116 18148-18153 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 18231-18239 Body_part denotes Monocyte http://purl.org/sig/ont/fma/fma62864
T118 18274-18282 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T119 18277-18282 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T120 18288-18293 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T121 18357-18365 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T122 18360-18365 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T123 18422-18427 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T124 18445-18454 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T125 18592-18601 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T126 18609-18620 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T127 18630-18641 Body_part denotes eosinophils http://purl.org/sig/ont/fma/fma62861
T128 18651-18662 Body_part denotes neutrophils http://purl.org/sig/ont/fma/fma62860
T129 18673-18683 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T130 18703-18707 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T131 18768-18781 Body_part denotes Myeloid Cells http://purl.org/sig/ont/fma/fma70339
T132 18776-18781 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T133 18904-18909 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T134 18965-18973 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T135 19017-19028 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T136 19259-19266 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T137 19283-19294 Body_part denotes lymph nodes http://purl.org/sig/ont/fma/fma5034
T138 19283-19288 Body_part denotes lymph http://purl.org/sig/ont/fma/fma9671
T139 19299-19305 Body_part denotes spleen http://purl.org/sig/ont/fma/fma7196
T140 19324-19335 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T141 19452-19460 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T142 19648-19652 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T143 19674-19677 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T144 19891-19895 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T145 19938-19943 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T146 20187-20197 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T147 20341-20345 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T148 20698-20702 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T149 20726-20738 Body_part denotes granulocytes http://purl.org/sig/ont/fma/fma62854
T150 20876-20886 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T151 20899-20909 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T152 21205-21218 Body_part denotes myeloid cells http://purl.org/sig/ont/fma/fma70339
T153 21213-21218 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 21332-21337 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T155 21354-21359 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 21394-21399 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T157 21460-21464 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T158 21483-21487 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T159 21587-21592 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T160 21699-21707 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T161 21702-21707 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T162 21732-21740 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T163 21735-21740 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T164 21758-21763 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T165 21790-21798 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T166 21845-21850 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T167 21883-21888 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T168 21960-21968 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T169 21963-21968 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T170 21987-21992 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T171 22211-22219 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T172 22214-22219 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T173 22252-22257 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T174 22328-22332 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T175 22333-22341 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T176 22336-22341 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T177 22445-22452 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T178 22448-22452 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T179 22592-22596 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T180 22597-22603 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T181 22651-22660 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T182 22681-22686 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T183 22783-22790 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T184 22786-22790 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T185 22823-22828 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T186 22836-22841 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T187 22876-22883 Body_part denotes NK Cell http://purl.org/sig/ont/fma/fma63147
T188 22879-22883 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T189 22926-22934 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T190 22929-22934 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T191 23075-23080 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T192 23111-23119 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T193 23187-23194 Body_part denotes NK-cell http://purl.org/sig/ont/fma/fma63147
T194 23190-23194 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T195 23423-23428 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T196 23485-23492 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T197 23488-23492 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T198 23647-23654 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T199 23650-23654 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T200 23767-23772 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T201 23869-23877 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T202 23892-23900 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T203 23895-23900 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T204 23923-23928 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T205 23937-23945 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T206 24156-24159 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T207 24195-24207 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T208 24246-24251 Body_part denotes ovary http://purl.org/sig/ont/fma/fma7209
T209 24258-24263 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T210 24325-24332 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T211 24328-24332 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T212 24427-24435 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T213 24466-24473 Body_part denotes NK Cell http://purl.org/sig/ont/fma/fma63147
T214 24469-24473 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T215 24515-24523 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T216 24518-24523 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T217 24540-24545 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T218 24725-24735 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T219 24852-24860 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T220 24855-24860 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T221 24892-24900 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T222 24895-24900 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T223 24943-24947 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T224 24948-24956 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T225 24951-24956 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T226 25121-25129 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T227 25124-25129 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T228 25145-25149 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T229 25217-25221 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T230 25264-25273 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T231 25283-25286 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T232 25379-25384 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T233 25430-25444 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T234 25482-25489 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T235 25485-25489 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T236 25550-25557 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T237 25553-25557 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T238 25653-25661 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T239 25656-25661 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T240 25711-25716 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T241 25888-25899 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T242 25940-25948 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T243 25943-25948 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T244 25958-25963 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T245 25984-25991 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T246 26069-26077 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T247 26072-26077 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T248 26088-26093 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T249 26155-26159 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T250 26202-26205 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T251 26325-26328 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T252 26444-26452 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T253 26447-26452 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T254 26557-26565 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T255 26560-26565 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T256 26644-26650 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T257 26738-26745 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T258 26741-26745 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T259 26958-26966 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T260 26961-26966 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T261 27098-27104 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T262 27204-27209 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T263 27239-27247 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T264 27294-27302 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T265 27297-27302 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T266 27355-27362 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T267 27358-27362 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T268 27499-27506 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T269 27502-27506 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T270 27600-27609 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T271 27623-27630 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T272 27626-27630 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T273 27678-27683 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T274 27754-27761 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T275 27757-27761 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T276 27987-27991 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T277 28082-28086 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T278 28190-28200 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T279 28320-28331 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T280 28339-28343 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T281 28460-28480 Body_part denotes alveolar macrophages http://purl.org/sig/ont/fma/fma83023
T282 28674-28684 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T283 28685-28696 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T284 28811-28815 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T285 28828-28833 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T286 28885-28890 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T287 28901-28905 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T288 28915-28923 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T289 28980-28985 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T290 29001-29006 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T291 29021-29026 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T292 29079-29083 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T293 29160-29164 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T294 29284-29289 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T295 29319-29325 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T296 29385-29390 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T297 29550-29554 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T298 29576-29581 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T299 29779-29784 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T300 29986-29991 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T301 30389-30393 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T302 30473-30477 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T303 30625-30630 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T304 30728-30732 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T305 30780-30785 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T306 30788-30792 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T307 30844-30849 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T308 30852-30857 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T309 31012-31017 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T310 31284-31293 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T311 31303-31308 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T312 31435-31439 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T313 31469-31474 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T314 31482-31489 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T315 31638-31642 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T316 31658-31669 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T317 31719-31722 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T318 31724-31735 Body_part denotes granulocyte http://purl.org/sig/ont/fma/fma62854
T319 31736-31746 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T320 31885-31890 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T321 31898-31903 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T322 31945-31953 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T323 32006-32011 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T324 32138-32142 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T325 32197-32205 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T326 32313-32322 Body_part denotes Cytokines http://purl.org/sig/ont/fma/fma84050
T327 32361-32365 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T328 32383-32388 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T329 32449-32460 Body_part denotes endothelium http://purl.org/sig/ont/fma/fma63916
T330 32549-32556 Body_part denotes spleens http://purl.org/sig/ont/fma/fma7196
T331 32561-32578 Body_part denotes hilar lymph nodes http://purl.org/sig/ont/fma/fma276990
T332 32653-32657 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T333 32667-32678 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T334 32893-32904 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T335 32946-32950 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T336 33034-33039 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T337 33040-33051 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T338 33161-33165 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T339 33337-33347 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T340 33368-33373 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T341 33491-33503 Body_part denotes neutrophilic http://purl.org/sig/ont/fma/fma62860
T342 33702-33706 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T343 33767-33771 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T344 33874-33878 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T345 33930-33938 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T346 33986-33990 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T347 34031-34038 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T348 34136-34141 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T349 34172-34177 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T350 34200-34205 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T351 34259-34264 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T352 34417-34421 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T353 34536-34544 Body_part denotes Th2 cell http://purl.org/sig/ont/fma/fma84385
T354 34540-34544 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T355 34565-34570 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T356 34571-34580 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T357 34630-34634 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T358 34780-34784 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T359 34874-34878 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T360 34920-34928 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T361 34997-35005 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T362 35136-35141 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T363 35428-35433 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T364 35615-35620 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T365 35730-35735 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T366 35872-35879 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T367 35917-35920 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T368 35972-35980 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T369 36073-36078 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T370 36085-36092 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T371 36264-36269 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T372 36348-36353 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T373 36404-36422 Body_part denotes regulatory T cells http://purl.org/sig/ont/fma/fma84070
T374 36417-36422 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T375 36475-36482 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T376 36494-36499 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T377 36560-36564 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T378 36678-36682 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T379 36855-36860 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T380 36867-36872 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T381 36936-36939 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T382 37098-37103 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T383 37183-37188 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T384 37264-37271 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T385 37371-37376 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T386 37621-37626 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T387 37925-37930 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T388 38038-38043 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T389 38083-38088 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T390 38253-38258 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T391 38415-38419 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T392 38495-38499 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T393 38573-38577 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T394 38800-38803 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T395 38811-38816 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T396 38948-38951 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T397 38959-38964 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T398 39129-39132 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T399 39140-39145 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T400 39288-39293 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T401 39370-39375 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T402 39526-39530 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T403 39579-39584 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T404 39600-39605 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T405 39835-39839 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T406 39935-39939 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T407 40085-40090 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T408 40133-40136 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T409 40376-40381 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T410 40419-40424 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T411 40536-40540 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T412 40810-40814 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T413 40959-40964 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T414 41242-41247 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T415 41318-41323 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T416 41461-41466 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T417 41645-41650 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T418 41724-41729 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T419 41755-41763 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T420 42002-42007 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T421 42246-42251 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T422 42508-42513 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T423 42526-42531 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T424 42565-42569 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T425 42580-42585 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T426 42707-42711 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T427 42864-42867 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T428 42880-42883 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T429 42927-42932 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T430 43132-43137 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T431 43454-43459 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T432 43727-43731 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T433 43906-43910 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T434 43930-43934 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T435 43939-43947 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T436 44138-44142 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T437 44226-44229 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T438 44231-44234 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T439 44239-44242 Body_part denotes IgA http://purl.org/sig/ont/fma/fma62874
T440 44261-44264 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T441 44336-44344 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T442 44582-44590 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T443 44795-44805 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T444 44840-44847 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T445 44867-44879 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T446 45002-45009 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T447 45350-45358 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T448 45377-45384 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T449 45401-45407 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T450 45514-45520 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T451 45614-45622 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T452 45670-45673 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T453 45678-45681 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T454 45700-45705 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T455 45763-45766 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T456 45809-45817 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T457 45913-45921 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T458 46047-46052 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T459 46182-46185 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T460 46196-46201 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T461 46214-46218 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T462 46345-46353 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T463 46354-46358 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T464 46875-46883 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T465 46986-46990 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T466 47030-47034 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T467 47205-47217 Body_part denotes plasma cells http://purl.org/sig/ont/fma/fma70574
T468 47205-47211 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T469 47212-47217 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T470 47342-47347 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T471 47420-47423 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T472 47429-47433 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T473 47451-47456 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T474 47526-47538 Body_part denotes plasma cells http://purl.org/sig/ont/fma/fma70574
T475 47526-47532 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T476 47533-47538 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T477 47609-47621 Body_part denotes plasma cells http://purl.org/sig/ont/fma/fma70574
T478 47609-47615 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T479 47616-47621 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T480 47635-47640 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T481 47701-47705 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T482 48030-48038 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T483 48073-48077 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T484 48211-48219 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T485 48230-48235 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T486 48299-48313 Body_part denotes T helper cells http://purl.org/sig/ont/fma/fma70572
T487 48308-48313 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T488 48320-48325 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T489 48450-48461 Body_part denotes plasma cell http://purl.org/sig/ont/fma/fma70574
T490 48457-48461 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T491 48506-48509 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T492 48517-48522 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T493 48571-48576 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T494 49094-49097 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T495 49387-49390 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T496 49673-49676 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T497 49758-49761 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T498 49937-49940 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T499 49979-49986 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T500 50005-50010 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T501 50050-50053 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T502 50210-50215 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T503 50252-50259 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T504 50269-50272 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T505 50280-50285 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T506 50348-50351 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T507 50361-50366 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T508 50562-50565 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T509 50576-50581 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T510 50663-50667 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T511 50837-50845 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T512 51167-51171 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T513 51271-51279 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T514 51758-51766 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T515 52070-52078 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T516 52148-52156 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T517 52262-52265 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T518 52336-52341 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T519 52356-52367 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T520 52372-52381 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T521 52427-52432 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T522 52521-52524 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T523 52553-52557 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T524 52599-52608 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T525 52613-52624 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T526 52632-52636 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T527 52670-52675 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T528 52768-52776 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T529 52785-52796 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T530 52866-52874 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T531 53553-53561 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T532 53604-53618 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T533 53898-53906 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T534 54813-54818 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T535 54969-54974 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T536 55065-55070 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T537 55079-55084 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T538 56349-56356 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T539 56597-56601 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T540 57266-57270 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T541 57343-57348 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T542 57711-57719 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T543 57734-57739 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T544 57748-57755 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T545 57772-57779 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T546 58067-58072 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T547 58510-58515 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T548 58613-58623 Body_part denotes Lymphocyte http://purl.org/sig/ont/fma/fma62863
T549 59573-59577 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T550 60887-60895 Body_part denotes Platelet http://purl.org/sig/ont/fma/fma62851
T551 60907-60915 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T552 60919-60929 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T553 61160-61167 Body_part denotes NK cell http://purl.org/sig/ont/fma/fma63147
T554 61163-61167 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T555 61197-61205 Body_part denotes NK cells http://purl.org/sig/ont/fma/fma63147
T556 61200-61205 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T557 61376-61381 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T558 61424-61429 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T559 61661-61666 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T560 61711-61737 Body_part denotes peripheral blood monocytes http://purl.org/sig/ont/fma/fma86713
T561 61779-61788 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T562 62030-62039 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T563 62166-62175 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T564 63024-63033 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T565 63088-63098 Body_part denotes eosinophil http://purl.org/sig/ont/fma/fma62861
T566 63150-63154 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T567 63161-63165 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T568 63168-63177 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T569 63239-63243 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T570 63244-63247 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T571 63295-63303 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T572 63330-63334 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T573 63504-63508 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T574 63635-63639 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T575 63670-63675 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T576 63749-63753 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T577 63845-63848 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T578 63852-63855 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T579 63865-63870 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T580 63928-63931 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T581 63933-63942 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T582 64029-64033 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T583 64044-64048 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T584 64146-64154 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T585 64183-64186 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T586 64299-64302 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T587 64417-64423 Body_part denotes Organs http://purl.org/sig/ont/fma/fma67498
T588 64493-64515 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T589 64517-64524 Body_part denotes kidneys http://purl.org/sig/ont/fma/fma7203
T590 64530-64536 Body_part denotes testis http://purl.org/sig/ont/fma/fma7210
T591 64598-64602 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T592 64660-64665 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T593 64667-64692 Body_part denotes alveolar epithelial cells http://purl.org/sig/ont/fma/fma62499
T594 64687-64692 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T595 64743-64759 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T596 64754-64759 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T597 64768-64773 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T598 64800-64811 Body_part denotes hepatocytes http://purl.org/sig/ont/fma/fma14515
T599 64813-64826 Body_part denotes Kupffer cells http://purl.org/sig/ont/fma/fma14656
T600 64821-64826 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T601 64831-64848 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T602 64843-64848 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T603 64902-64907 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T604 64975-64986 Body_part denotes enterocytes http://purl.org/sig/ont/fma/fma62122
T605 64994-65009 Body_part denotes small intestine http://purl.org/sig/ont/fma/fma7200
T606 65026-65031 Body_part denotes colon http://purl.org/sig/ont/fma/fma14543
T607 65121-65128 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T608 65134-65145 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T609 65152-65162 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T610 65166-65176 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T611 65476-65486 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T612 65542-65553 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T613 65797-65807 Body_part denotes neutrophil http://purl.org/sig/ont/fma/fma62860
T614 65811-65821 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T615 66237-66251 Body_part denotes blood platelet http://purl.org/sig/ont/fma/fma62851
T616 66256-66266 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T617 66443-66454 Body_part denotes endothelium http://purl.org/sig/ont/fma/fma63916
T618 66459-66468 Body_part denotes monocytic http://purl.org/sig/ont/fma/fma62864
T619 66758-66763 Body_part denotes Blood http://purl.org/sig/ont/fma/fma9670
T620 66925-66934 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T621 67331-67334 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T622 67575-67579 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T623 67683-67691 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T624 68546-68559 Body_part denotes helper T cell http://purl.org/sig/ont/fma/fma70572
T625 68555-68559 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T626 68589-68593 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T627 68655-68659 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T628 68661-68674 Body_part denotes helper T cell http://purl.org/sig/ont/fma/fma70572
T629 68670-68674 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T630 68693-68697 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T631 69768-69777 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T632 69793-69798 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T633 69882-69890 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T634 70076-70085 Body_part denotes leukocyte http://purl.org/sig/ont/fma/fma62852
T635 70090-70100 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T636 70206-70229 Body_part denotes gastrointestinal tracts http://purl.org/sig/ont/fma/fma71132
T637 70234-70241 Body_part denotes kidneys http://purl.org/sig/ont/fma/fma7203
T638 70382-70391 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T639 70496-70506 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T640 70961-70964 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T641 70969-70972 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T642 71087-71090 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T643 71236-71240 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T644 71320-71323 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T645 71411-71421 Body_part denotes pyrimidine http://purl.org/sig/ont/fma/fma82773
T646 72053-72069 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T647 72064-72069 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T648 72759-72762 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T649 72944-72949 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T650 73093-73096 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T651 73107-73110 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T652 73162-73165 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T653 73348-73351 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T654 73386-73397 Body_part denotes nucleotides http://purl.org/sig/ont/fma/fma82740
T655 73442-73445 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T656 73857-73861 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T657 74422-74431 Body_part denotes lysosomes http://purl.org/sig/ont/fma/fma63836
T658 74528-74537 Body_part denotes lysosomes http://purl.org/sig/ont/fma/fma63836
T659 74586-74589 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T660 74695-74703 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T661 74705-74714 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T662 74816-74819 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T663 74871-74880 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T664 74885-74896 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T665 75074-75080 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T666 75118-75121 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T667 75123-75134 Body_part denotes granulocyte http://purl.org/sig/ont/fma/fma62854
T668 75135-75145 Body_part denotes macrophage http://purl.org/sig/ont/fma/fma63261
T669 75221-75224 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T670 75235-75238 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T671 75580-75583 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T672 78353-78356 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T673 79108-79117 Body_part denotes lysosomal http://purl.org/sig/ont/fma/fma63836
T674 79219-79222 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T675 79270-79279 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T676 79324-79342 Body_part denotes regulatory T cells http://purl.org/sig/ont/fma/fma84070
T677 79337-79342 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T678 79509-79514 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T679 79586-79595 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T680 79905-79910 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T681 80355-80366 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T682 80389-80393 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T683 80525-80529 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T684 81011-81014 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T685 81861-81864 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T686 82086-82089 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T687 82408-82413 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T688 82816-82819 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T689 82916-82923 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T690 83778-83781 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T691 84520-84528 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T692 84585-84587 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T693 84810-84812 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T694 85018-85020 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T695 86108-86110 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T696 86882-86887 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T697 87196-87198 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T698 87516-87524 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T699 87630-87640 Body_part denotes human body http://purl.org/sig/ont/fma/fma305853
T700 87649-87652 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T701 87900-87905 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T702 88013-88029 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T703 88024-88029 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T704 88073-88078 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T705 89515-89523 Body_part denotes Cytokine http://purl.org/sig/ont/fma/fma84050
T706 89597-89606 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T707 89828-89836 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T708 90211-90219 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T709 90349-90354 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T710 90371-90374 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T711 90553-90562 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T712 90578-90582 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T713 90588-90598 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T714 90775-90779 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T715 90800-90809 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T716 90814-90825 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T717 90866-90875 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T718 90888-90896 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T719 91150-91159 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T720 91161-91172 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T721 91197-91205 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T722 91453-91461 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T723 91733-91741 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T724 92188-92198 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T725 92245-92249 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T726 92284-92289 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T727 93510-93518 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T728 93524-93533 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T729 93575-93578 Body_part denotes CSF http://purl.org/sig/ont/fma/fma20935
T730 93588-93597 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T731 93766-93771 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T732 93880-93888 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T733 93988-93998 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T734 94016-94022 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T735 94101-94114 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T736 94977-94982 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T737 95306-95314 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T738 95483-95488 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T739 95653-95661 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T740 95710-95718 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T741 96551-96556 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T742 96677-96684 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T743 96820-96828 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T744 96999-97007 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T745 97102-97113 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T746 97328-97338 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T747 97370-97378 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T748 98314-98322 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T749 98848-98856 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T750 98921-98929 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T751 99090-99098 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T752 99484-99492 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T753 99604-99611 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T754 99886-99892 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 12141-12150 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483
T2 13780-13785 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 14427-14432 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T4 14813-14819 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T5 15264-15269 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T6 15289-15294 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T7 15365-15371 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T8 16157-16161 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T9 17051-17055 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T10 17602-17611 Body_part denotes epithelia http://purl.obolibrary.org/obo/UBERON_0000483
T11 18288-18293 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T12 19283-19294 Body_part denotes lymph nodes http://purl.obolibrary.org/obo/UBERON_0000029
T13 19283-19288 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T14 19299-19305 Body_part denotes spleen http://purl.obolibrary.org/obo/UBERON_0002106
T15 20341-20345 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T16 20698-20702 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T17 21883-21888 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T18 21987-21992 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T19 22328-22332 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T20 22592-22596 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T21 22597-22603 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T22 22823-22828 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T23 24540-24545 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T24 24943-24947 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T25 25145-25149 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T26 25379-25384 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T27 25711-25716 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T28 27204-27209 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T29 27987-27991 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T30 28082-28086 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T31 28190-28200 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T32 28339-28343 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T33 29319-29325 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T34 29576-29581 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T35 30780-30785 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T36 30844-30849 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T37 31469-31474 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T38 31898-31903 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T39 32006-32011 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T40 32383-32388 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T41 32424-32430 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T42 32449-32460 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986
T43 32549-32556 Body_part denotes spleens http://purl.obolibrary.org/obo/UBERON_0002106
T44 32567-32578 Body_part denotes lymph nodes http://purl.obolibrary.org/obo/UBERON_0000029
T45 32567-32572 Body_part denotes lymph http://purl.obolibrary.org/obo/UBERON_0002391
T46 33034-33039 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T47 34565-34570 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T48 38038-38043 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T49 39526-39530 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T50 45700-45705 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T51 47420-47423 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T52 48571-48576 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T53 50005-50010 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T54 52553-52557 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T55 52632-52636 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T56 52670-52675 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T57 54813-54818 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T58 54969-54974 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T59 55065-55070 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T60 55079-55084 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T61 57099-57104 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T62 57343-57348 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T63 57734-57739 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T64 58067-58072 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T65 58367-58373 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T66 58510-58515 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T67 59573-59577 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T68 61722-61727 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T69 63504-63508 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T70 64417-64423 Body_part denotes Organs http://purl.obolibrary.org/obo/UBERON_0000062
T71 64530-64536 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473
T72 64580-64586 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T73 64768-64773 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T74 64902-64907 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T75 64994-65009 Body_part denotes small intestine http://purl.obolibrary.org/obo/UBERON_0002108
T76 65000-65009 Body_part denotes intestine http://purl.obolibrary.org/obo/UBERON_0000160
T77 65026-65031 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T78 66237-66242 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T79 66443-66454 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986
T80 66758-66763 Body_part denotes Blood http://purl.obolibrary.org/obo/UBERON_0000178
T81 69793-69798 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T82 70186-70192 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T83 70478-70484 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T84 71236-71240 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T85 73857-73861 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T86 78353-78356 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T87 80389-80393 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T88 81011-81014 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T89 81861-81864 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T90 82086-82089 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T91 82408-82413 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T92 82816-82819 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T93 83778-83781 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T94 86882-86887 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T95 92245-92249 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T96 92284-92289 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T97 94101-94114 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T98 95483-95488 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T99 100055-100060 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T100 102554-102559 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T101 102938-102943 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T102 103210-103215 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T103 112493-112498 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 14-22 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 67-91 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 93-101 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 123-170 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T5 123-156 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T6 172-180 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 335-342 Disease denotes COVID19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 472-480 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T9 483-492 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T10 722-730 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T11 733-742 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T12 749-773 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T13 775-783 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 805-852 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T15 805-838 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T16 854-862 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 1017-1024 Disease denotes COVID19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 1154-1162 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T19 1165-1174 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T20 1404-1412 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 1415-1424 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T22 1499-1546 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T23 1499-1532 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T24 1548-1556 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 1578-1602 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T26 1604-1612 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 1752-1760 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 1847-1862 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T29 1853-1862 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T30 2465-2484 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T31 2497-2505 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T32 2535-2539 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T33 2563-2571 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T34 2734-2742 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 2765-2773 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 3048-3056 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 3145-3153 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 3580-3588 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T39 3670-3678 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 3865-3873 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T41 4055-4063 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T42 4135-4143 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T43 4347-4355 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 4854-4859 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T45 5127-5136 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T46 5230-5238 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T47 5323-5331 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T48 5624-5632 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T49 5793-5801 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 5831-5839 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 5900-5909 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T52 6081-6096 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T53 6087-6096 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T54 6217-6225 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T55 6360-6368 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T56 6594-6602 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T57 7124-7132 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 7838-7846 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 8434-8442 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 8864-8872 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T61 9026-9034 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 9427-9435 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T63 9548-9556 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T64 9707-9715 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 9783-9791 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 9944-9952 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 10102-10110 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 10301-10309 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 10423-10431 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 10871-10879 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 11144-11152 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T72 11199-11207 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 11285-11293 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 11296-11305 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T75 11354-11362 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 11365-11374 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T77 11669-11677 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 11724-11732 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T79 11748-11757 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T80 12356-12364 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T81 12600-12612 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T82 12625-12633 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 12875-12883 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 13162-13170 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 13215-13225 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T86 13552-13560 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T87 13589-13624 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T88 13595-13624 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T89 13626-13630 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T90 13660-13663 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T92 13669-13680 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T93 13732-13740 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T94 13829-13837 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 14436-14444 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T96 14700-14708 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T97 15056-15060 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T98 15210-15218 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T99 15407-15415 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T100 15457-15465 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T101 15518-15526 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T102 15604-15612 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T103 15678-15686 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T104 15713-15721 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T105 15724-15733 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T106 15773-15775 Disease denotes AM http://purl.obolibrary.org/obo/MONDO_0020320
T107 15926-15942 Disease denotes hypersensitivity http://purl.obolibrary.org/obo/MONDO_0000605|http://purl.obolibrary.org/obo/MONDO_0005271
T109 15962-15966 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T110 16044-16052 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T111 16371-16379 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 16556-16564 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T113 16694-16703 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T114 16944-16952 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T115 17045-17062 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T117 17056-17062 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T118 17372-17380 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 17383-17392 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T120 17488-17496 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 18009-18012 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T123 18115-18123 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T124 18408-18412 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T125 18721-18765 Disease denotes secondary hemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015542
T126 18731-18765 Disease denotes hemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015540
T127 18809-18821 Disease denotes Inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T128 19070-19078 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T129 19081-19090 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T130 19186-19194 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 19235-19243 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T132 19339-19347 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 19496-19504 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 19690-19734 Disease denotes secondary hemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015542
T135 19700-19734 Disease denotes hemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015540
T136 19751-19767 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T137 19949-19952 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T139 20067-20075 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T140 20078-20087 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 20332-20340 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T142 20547-20555 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T143 20742-20750 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T144 21123-21131 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T145 21134-21143 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T146 21222-21230 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 21892-21900 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 21996-22004 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T149 22471-22490 Disease denotes influenza infection http://purl.obolibrary.org/obo/MONDO_0005812
T150 22481-22490 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T151 22566-22574 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T152 22690-22698 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T153 22845-22853 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T154 23403-23411 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T155 23507-23515 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T156 23579-23587 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T157 23590-23599 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T158 23978-23982 Disease denotes ADCC http://purl.obolibrary.org/obo/MONDO_0008734
T159 23997-24016 Disease denotes influenza infection http://purl.obolibrary.org/obo/MONDO_0005812
T160 24007-24016 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T161 24099-24103 Disease denotes ADCC http://purl.obolibrary.org/obo/MONDO_0008734
T162 24138-24146 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T163 24182-24190 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T164 24389-24398 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T165 24445-24449 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T166 24486-24494 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T167 24497-24506 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T168 24549-24557 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T169 24868-24877 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T170 24995-25003 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T171 25067-25075 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T172 25727-25735 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T173 25742-25750 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T174 25753-25762 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T175 25995-26003 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T176 26099-26107 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 26331-26340 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T178 26458-26466 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T179 26614-26622 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T180 27108-27116 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T181 27516-27520 Disease denotes ADCC http://purl.obolibrary.org/obo/MONDO_0008734
T182 27658-27666 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T183 27775-27783 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T184 27835-27843 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T185 27846-27855 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T186 27924-27932 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T187 27935-27944 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T188 28106-28125 Disease denotes influenza infection http://purl.obolibrary.org/obo/MONDO_0005812
T189 28116-28125 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T190 28348-28357 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T191 28709-28717 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T192 28755-28763 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T193 28766-28775 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T194 28861-28877 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T195 29178-29186 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T196 29189-29198 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T197 29351-29359 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T198 29620-29628 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T199 29631-29640 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T200 29712-29723 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T201 29808-29816 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T202 29950-29961 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T203 30072-30080 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T204 30505-30513 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T205 30558-30574 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T206 30604-30619 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T207 30610-30619 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T208 30746-30754 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T209 30895-30907 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T210 30934-30942 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T211 31085-31093 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T212 31693-31698 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T213 31970-31981 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T214 32612-32620 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T215 32975-32984 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T216 33113-33121 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T217 33284-33288 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T218 33299-33307 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T219 33310-33319 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T220 33462-33470 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T221 33642-33653 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T222 33657-33665 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T223 33745-33753 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T224 33838-33846 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T225 33849-33858 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T226 33919-33927 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T227 34061-34069 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T228 34359-34363 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T229 34797-34805 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T230 34808-34817 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T231 34855-34863 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T232 35046-35054 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T233 35248-35256 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T234 35290-35294 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T235 35726-35728 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T237 35825-35829 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T238 36739-36747 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T239 37114-37122 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T240 37477-37487 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T241 37532-37540 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T242 37662-37666 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T243 37720-37730 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T244 37779-37787 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T245 37903-37911 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T246 38145-38153 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T247 38217-38225 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T248 38436-38444 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T249 38652-38660 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T250 38896-38904 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T251 39013-39032 Disease denotes autoimmune diseases http://purl.obolibrary.org/obo/MONDO_0007179
T252 39042-39060 Disease denotes multiple sclerosis http://purl.obolibrary.org/obo/MONDO_0005301
T253 39064-39093 Disease denotes juvenile rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0011429
T254 39073-39093 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T255 39084-39093 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T256 39304-39312 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T257 39408-39412 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T258 39413-39425 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T259 39517-39525 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T260 39653-39662 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T261 39663-39672 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T262 39749-39757 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T263 39851-39859 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T264 39964-39972 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T265 40343-40351 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T266 40558-40566 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T267 40623-40631 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T268 41875-41878 Disease denotes PMA http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687
T270 42018-42026 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T271 42430-42438 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T272 42441-42450 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T273 42960-42968 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T274 43148-43156 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T275 43750-43758 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T276 43761-43770 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T277 44108-44116 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T278 44305-44314 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T279 44357-44365 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T280 44436-44444 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T281 44447-44456 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T282 44509-44517 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T283 44818-44826 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T284 45331-45339 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T285 45413-45421 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T286 45477-45485 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T287 45526-45534 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T288 45563-45571 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T289 45644-45652 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T290 45979-45987 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T291 46109-46117 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T292 46153-46162 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T293 46249-46257 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T294 46374-46382 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T295 46651-46661 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T296 46687-46695 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T297 46792-46800 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T298 47194-47203 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T299 47388-47397 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T300 47726-47734 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T301 47895-47903 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T302 48580-48588 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T303 48667-48675 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T304 48676-48685 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T305 48705-48713 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T306 48716-48725 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T307 48799-48808 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T308 49176-49185 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T309 49314-49322 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T310 49325-49334 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T311 49411-49419 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T312 49450-49459 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T313 49581-49589 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T314 49777-49786 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T315 49905-49914 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T316 49953-49961 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T317 50239-50247 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T318 50316-50325 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T319 50426-50435 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T320 50542-50550 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T321 50596-50605 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T322 50784-50792 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T323 50992-51000 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T324 51036-51045 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T325 51290-51298 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T326 51873-51881 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T327 52180-52183 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T328 52467-52475 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T329 52547-52564 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T331 52558-52564 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T332 52566-52569 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T333 52702-52710 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T334 52735-52744 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T335 52748-52756 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T336 52826-52829 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T337 52982-52985 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T338 53029-53037 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T339 53122-53130 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T340 53247-53255 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T341 53310-53318 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T342 53490-53493 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T343 53643-53646 Disease denotes ADE http://purl.obolibrary.org/obo/MONDO_0019383
T344 53668-53676 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T345 53820-53828 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T346 53831-53840 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T347 54115-54123 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T348 54250-54258 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T349 54454-54462 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T350 54465-54474 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T351 54721-54729 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T352 54859-54867 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T353 55033-55041 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T354 55121-55130 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T355 55319-55327 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T356 55517-55525 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T357 55590-55598 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T358 55697-55705 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T359 55978-55986 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T360 56309-56317 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T361 57042-57050 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T362 57740-57747 Disease denotes amyloid http://purl.obolibrary.org/obo/MONDO_0019065
T363 57861-57869 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T364 57902-57918 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T365 58002-58005 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T367 58223-58231 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T368 58384-58392 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T369 58559-58567 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T370 59250-59259 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T371 59270-59279 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T372 59340-59348 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T373 59821-59827 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T374 59980-59988 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T375 60204-60242 Disease denotes disseminated intravascular coagulation http://purl.obolibrary.org/obo/MONDO_0001243
T376 60338-60344 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T377 60857-60865 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T378 60989-61005 Disease denotes Thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T379 61072-61078 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T380 61082-61090 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T381 61243-61251 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T382 62252-62260 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T383 62556-62575 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T384 63072-63075 Disease denotes PCT http://purl.obolibrary.org/obo/MONDO_0008296|http://purl.obolibrary.org/obo/MONDO_0015104
T386 63111-63119 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T387 63693-63701 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T388 63957-63965 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T389 64135-64143 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T390 64172-64180 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T391 64288-64296 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T392 64466-64474 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T393 64908-64914 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T394 65251-65262 Disease denotes Lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T395 65317-65325 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T396 65972-65980 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T397 66523-66539 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T398 66613-66621 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T399 66907-66915 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T400 66994-67002 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T401 67192-67211 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T402 67737-67745 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T403 68099-68118 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T404 68476-68484 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T405 68601-68603 Disease denotes TS http://purl.obolibrary.org/obo/MONDO_0010979|http://purl.obolibrary.org/obo/MONDO_0016455
T407 68617-68619 Disease denotes TS http://purl.obolibrary.org/obo/MONDO_0010979|http://purl.obolibrary.org/obo/MONDO_0016455
T409 68741-68743 Disease denotes TS http://purl.obolibrary.org/obo/MONDO_0010979|http://purl.obolibrary.org/obo/MONDO_0016455
T411 68801-68810 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T412 69586-69594 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T413 69714-69725 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T414 69799-69817 Disease denotes hypercoagulability http://purl.obolibrary.org/obo/MONDO_0002305
T415 69838-69846 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T416 70067-70085 Disease denotes disease, leukocyte http://purl.obolibrary.org/obo/MONDO_0004805
T417 70146-70154 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T418 70269-70281 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T419 70432-70443 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T420 70788-70804 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T421 70870-70878 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T422 70930-70938 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T423 71144-71152 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T424 71241-71247 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T425 71270-71278 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T426 71453-71461 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T427 71739-71747 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T428 71921-71930 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T429 72026-72034 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T430 72198-72206 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T431 72305-72313 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T432 72490-72498 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T433 72726-72734 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T434 72964-72972 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T435 73572-73580 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T436 73583-73596 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T437 73753-73761 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T438 73764-73774 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T439 73878-73887 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T440 74041-74049 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T441 74052-74062 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T442 74113-74121 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T443 74361-74369 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T444 74372-74382 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T445 74763-74771 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T446 74772-74775 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T448 74931-74939 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T449 75096-75104 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T450 75657-75666 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T451 75667-75677 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T452 75827-75835 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T453 75836-75845 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T454 76106-76114 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T455 76197-76201 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T456 76247-76251 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T457 76467-76475 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T458 76733-76741 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T459 77224-77232 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T460 77790-77798 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T461 78021-78028 Disease denotes Allergy http://purl.obolibrary.org/obo/MONDO_0005271
T462 78033-78043 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T463 78541-78549 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T464 78594-78602 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T465 78779-78787 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T466 78936-78944 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T467 79024-79032 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T468 79491-79500 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T469 79520-79528 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T470 79938-79947 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T471 80264-80272 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T472 80408-80416 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T473 80650-80658 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T474 80791-80799 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T475 80922-80930 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T476 81059-81067 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T477 81759-81767 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T478 82143-82151 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T479 82517-82525 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T480 82694-82702 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T481 83263-83271 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T482 83575-83583 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T483 84044-84052 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T484 84399-84407 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T485 84511-84515 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T486 84763-84771 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T487 84778-84786 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T488 84789-84798 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T489 84923-84931 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T490 84934-84943 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T491 85071-85075 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T492 85206-85210 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T493 85373-85381 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T494 85437-85445 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T495 85860-85864 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T496 86443-86451 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T497 86531-86535 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T498 87206-87214 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T499 87545-87553 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T500 87666-87674 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T501 88224-88236 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T502 88416-88424 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T503 88530-88540 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T504 88572-88580 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T505 88583-88592 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T506 88814-88823 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T507 89109-89117 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T508 89131-89139 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T509 89185-89193 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T510 89671-89679 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T511 90070-90078 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T512 90238-90246 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T513 90311-90322 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T514 90412-90420 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T515 90438-90446 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T516 90684-90692 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T517 90879-90887 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T518 91055-91065 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T519 91077-91085 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T520 91465-91473 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T521 91485-91488 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T523 91809-91817 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T524 91818-91821 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T526 91826-91835 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T527 91955-91963 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T528 92410-92420 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T529 92616-92624 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T530 92625-92634 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T531 93676-93684 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T532 93685-93688 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T534 93775-93783 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T535 93935-93943 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T536 94035-94043 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T537 94146-94154 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T538 94307-94315 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T539 94521-94529 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T540 94610-94620 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T541 94698-94706 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T542 94749-94757 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T543 94760-94769 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T544 95342-95350 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T545 95621-95629 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T546 95727-95735 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T547 95800-95808 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T548 95923-95931 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T549 96004-96012 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T550 96122-96131 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T551 96185-96193 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T552 96217-96225 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T553 96228-96236 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T554 96243-96251 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T555 96341-96349 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T556 96399-96407 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T557 96468-96476 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T558 96593-96601 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T559 96604-96613 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T560 96664-96672 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T561 96736-96744 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T562 96953-96961 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T563 97027-97035 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T564 97184-97192 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T565 97304-97312 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T566 97448-97456 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T567 97597-97605 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T568 97774-97782 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T569 98611-98619 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T570 98895-98903 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T571 99004-99012 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T572 99206-99211 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T573 99280-99288 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T574 99836-99844 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T575 99851-99859 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T576 100260-100268 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T577 100419-100429 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T578 100457-100466 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T579 100497-100511 Disease denotes H1N1 influenza http://purl.obolibrary.org/obo/MONDO_0005460
T580 100502-100511 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T581 100537-100545 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T582 100710-100718 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T583 100836-100844 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T584 101481-101489 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T585 101664-101672 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T586 101821-101830 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T587 102106-102114 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T588 102620-102635 Disease denotes lymphocytopenia http://purl.obolibrary.org/obo/MONDO_0003783
T589 102684-102692 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T590 103559-103567 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T591 103710-103718 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T592 103749-103757 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T593 103760-103769 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T594 103977-103985 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T595 104239-104247 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T596 104320-104328 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T597 104529-104537 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T598 104662-104671 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T599 104792-104801 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T600 104837-104845 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T601 104952-104960 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T602 105210-105218 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T603 105221-105230 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T604 105473-105482 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T605 105644-105652 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T606 105782-105791 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T607 105929-105938 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T608 106199-106207 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T609 106636-106644 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T610 106651-106659 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T611 107174-107182 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T612 107286-107294 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T613 107352-107360 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T614 107663-107671 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T615 108362-108371 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T616 109309-109319 Disease denotes S sequence http://purl.obolibrary.org/obo/MONDO_0007821
T617 109355-109357 Disease denotes SE http://purl.obolibrary.org/obo/MONDO_0002125
T618 109525-109528 Disease denotes Ad5 http://purl.obolibrary.org/obo/MONDO_0011194
T619 109838-109846 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T620 109938-109946 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T621 110037-110045 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T622 110115-110123 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T623 110353-110361 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T624 110415-110421 Disease denotes rabies http://purl.obolibrary.org/obo/MONDO_0019173
T625 110440-110448 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T626 110614-110619 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T627 110632-110643 Disease denotes hepatitis A http://purl.obolibrary.org/obo/MONDO_0005790
T628 110632-110641 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T629 110683-110692 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T630 110707-110716 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T631 110756-110760 Disease denotes Zika http://purl.obolibrary.org/obo/MONDO_0018661
T632 110837-110845 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T633 110848-110857 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T634 111019-111027 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T635 111163-111171 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T636 111264-111272 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T637 111585-111593 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T638 111738-111746 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T639 112099-112107 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T640 112171-112179 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T641 112807-112815 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T642 113214-113222 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T643 113411-113419 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T644 113454-113462 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T645 113734-113742 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T646 113745-113755 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T647 113805-113813 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T648 113912-113920 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T649 113976-113984 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T650 114000-114010 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T651 114017-114020 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T653 114071-114079 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T654 114134-114144 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T655 114256-114265 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T656 114315-114323 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T657 114545-114553 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T658 114676-114684 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T659 114857-114860 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T661 114906-114917 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T662 115162-115172 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T663 115255-115263 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T664 115302-115310 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T665 117221-117227 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T666 117631-117637 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 99983-99984 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 100025-100029 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T3 100107-100108 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T4 100163-100169 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T5 100171-100173 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T6 100345-100347 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T7 100356-100359 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T8 100611-100616 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T9 100754-100760 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T10 100821-100823 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T11 100906-100908 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T12 101133-101135 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T13 101165-101166 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 101308-101310 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T15 101320-101322 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T16 101331-101334 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T17 101508-101511 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T18 101532-101534 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T19 101618-101620 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T20 101653-101654 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 101696-101698 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T22 101880-101882 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T23 101964-101970 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T24 102088-102094 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T25 102157-102159 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T26 102211-102213 http://purl.obolibrary.org/obo/CLO_0009715 denotes yo
T27 102230-102232 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T28 102466-102468 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T29 102472-102474 http://purl.obolibrary.org/obo/CLO_0009715 denotes yo
T30 102554-102559 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T31 102649-102653 http://purl.obolibrary.org/obo/CLO_0008947 denotes SaO2
T32 102649-102653 http://purl.obolibrary.org/obo/CLO_0050140 denotes SaO2
T33 102799-102801 http://purl.obolibrary.org/obo/CLO_0009715 denotes yo
T34 102838-102840 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T35 102938-102943 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T36 103004-103006 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T37 103049-103051 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T38 103130-103132 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T39 103133-103135 http://purl.obolibrary.org/obo/CLO_0009715 denotes yo
T40 103146-103148 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T41 103210-103215 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T42 103228-103230 http://purl.obolibrary.org/obo/CLO_0009715 denotes yo
T43 103286-103288 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T44 103573-103574 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T45 103601-103604 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T46 103659-103663 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T47 103681-103682 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 103792-103795 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T49 103796-103797 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 103918-103924 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T51 104011-104014 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T52 104024-104025 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 104141-104142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 104204-104210 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T55 104312-104319 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T56 104351-104352 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T57 104400-104406 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T58 104479-104486 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T59 104506-104507 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T60 104569-104572 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T61 104703-104706 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T62 104911-104915 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T63 104924-104927 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T64 104999-105002 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T65 105115-105121 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T66 105162-105168 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T67 105535-105538 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T68 105669-105675 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T69 105752-105758 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T70 105812-105819 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T71 105820-105826 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T72 105839-105847 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T73 105880-105886 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T74 105914-105916 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T75 105956-105959 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T76 105961-105968 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T77 106033-106036 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T78 106038-106045 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T79 106057-106064 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T80 106066-106068 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T81 106066-106068 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T82 106124-106130 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T83 106243-106244 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 106560-106567 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T85 106735-106736 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T86 106741-106747 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T87 107118-107121 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T88 107220-107221 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T89 107226-107232 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T90 107377-107383 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T91 107756-107757 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 107825-107832 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T93 107855-107862 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T94 107877-107889 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T95 107899-107900 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T96 108112-108113 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 108130-108132 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T98 108372-108377 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T99 108487-108494 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T100 108498-108499 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T101 108554-108569 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T102 108744-108750 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T103 109155-109159 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T104 109217-109219 http://purl.obolibrary.org/obo/CLO_0002105 denotes c2
T105 109217-109219 http://purl.obolibrary.org/obo/CLO_0051742 denotes c2
T106 109859-109874 http://purl.obolibrary.org/obo/CL_0000451 denotes dendritic cells
T107 109971-109980 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T108 110204-110212 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T109 110422-110427 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T110 110451-110453 http://purl.obolibrary.org/obo/CLO_0008882 denotes rS
T111 110580-110585 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T112 110620-110625 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T113 110642-110643 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T114 110644-110649 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T115 110656-110661 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T116 110693-110694 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T117 110695-110700 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T118 110717-110718 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T119 110719-110724 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T120 110761-110766 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T121 110808-110809 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T122 110858-110861 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T123 110950-110957 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T124 111118-111119 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T125 111194-111197 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T126 111280-111281 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 111298-111299 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 111999-112003 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T129 112136-112142 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T130 112448-112449 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T131 112706-112707 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 112880-112887 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T133 113108-113109 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T134 113263-113268 http://purl.obolibrary.org/obo/CLO_0001658 denotes ACTIV
T135 113463-113466 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T136 113561-113564 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T137 113630-113633 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T138 113639-113640 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T139 113693-113696 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T140 113843-113844 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T141 114326-114329 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T142 114330-114331 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T143 114928-114934 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T144 114939-114946 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T145 115333-115334 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 115747-115750 http://purl.obolibrary.org/obo/CLO_0002697 denotes Dan
T147 116099-116102 http://purl.obolibrary.org/obo/CLO_0001914 denotes Tim
T148 116582-116585 http://purl.obolibrary.org/obo/CLO_0002421 denotes Cho
T149 116582-116585 http://purl.obolibrary.org/obo/CLO_0052479 denotes Cho
T150 116582-116585 http://purl.obolibrary.org/obo/CLO_0052480 denotes Cho
T151 116582-116585 http://purl.obolibrary.org/obo/CLO_0052483 denotes Cho
T152 116582-116585 http://purl.obolibrary.org/obo/CLO_0052484 denotes Cho
T153 116582-116585 http://purl.obolibrary.org/obo/CLO_0052485 denotes Cho
T154 116741-116742 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T155 116965-116967 http://purl.obolibrary.org/obo/CLO_0007622 denotes MD
T156 117959-117962 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T89115 184-187 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T75564 866-869 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T50209 1669-1670 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T39945 1700-1712 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T15961 1728-1730 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T45606 1834-1835 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86620 2063-2064 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74980 2112-2115 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T78216 2220-2224 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T29604 2280-2281 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87410 2309-2314 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T77204 2318-2323 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T18672 2858-2861 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T39663 3005-3008 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T98317 3034-3035 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84014 3449-3453 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T92316 3449-3453 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T1646 3571-3576 http://purl.obolibrary.org/obo/UBERON_0007688 denotes field
T78093 3617-3622 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T23978 3977-3984 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T78716 4069-4078 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T56810 4101-4106 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T18418 4301-4310 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T45806 4331-4338 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T94539 4631-4641 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T73988 4654-4663 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T49019 4722-4744 http://purl.obolibrary.org/obo/PR_000024990 denotes type I/III interferons
T2518 4854-4881 http://purl.obolibrary.org/obo/PR_000000134 denotes tumor necrosis factor alpha
T59961 4895-4908 http://purl.obolibrary.org/obo/PR_000001091 denotes interleukin-1
T18190 4930-4932 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T94064 5003-5008 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T43446 5301-5302 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40624 5468-5473 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T71882 5591-5594 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T40767 5662-5670 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T89140 5910-5913 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T926 5982-5986 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T51889 6062-6063 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76060 6166-6175 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T51305 6387-6388 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41210 6480-6490 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell lines
T80754 6510-6515 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T25559 6521-6522 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98223 6523-6529 http://purl.obolibrary.org/obo/NCBITaxon_9669 denotes ferret
T66742 6891-6897 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T27278 7060-7069 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T38942 7264-7271 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T89792 7524-7534 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T41265 7772-7780 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T18305 8414-8424 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T87499 8471-8481 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T73131 8573-8583 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T41258 8648-8657 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T15775 8765-8774 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T46552 9105-9115 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T26255 9137-9146 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T87993 9225-9227 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T52388 9225-9227 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T27533 9528-9537 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T78168 9595-9604 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T65422 9740-9749 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T77228 9815-9824 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T35185 9883-9892 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T5869 9994-10003 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T15916 10249-10251 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T55083 10249-10251 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T42053 10383-10387 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T23083 10656-10665 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T77334 10735-10741 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T59968 10843-10851 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T46300 11604-11605 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30392 11707-11713 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T99176 12134-12140 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T92879 12250-12259 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T54720 12270-12278 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T62975 12417-12427 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T55060 12549-12551 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T96273 12673-12677 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T33585 12742-12744 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T27677 12742-12744 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T80865 12756-12758 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T85633 12756-12758 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T17975 12910-12911 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96342 12984-12985 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99213 13181-13186 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T18347 13275-13280 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T77462 13323-13351 http://purl.obolibrary.org/obo/CL_0000990 denotes conventional dendritic cells
T96405 13353-13357 http://purl.obolibrary.org/obo/CL_0000990 denotes cDCs
T71812 13360-13368 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T96137 13457-13458 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T9046 13769-13803 http://purl.obolibrary.org/obo/CL_0000842 denotes peripheral blood mononuclear cells
T36496 13769-13803 http://purl.obolibrary.org/obo/CL_2000001 denotes peripheral blood mononuclear cells
T53109 13858-13859 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T80797 13951-13960 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T22406 13961-13964 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T68231 13966-13973 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T30982 14005-14014 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T77719 14121-14125 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T84486 14184-14193 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytic
T622 14261-14270 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T4606 14427-14432 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T52480 14427-14432 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T71894 14521-14524 http://purl.obolibrary.org/obo/CLO_0002742 denotes Del
T47578 14766-14774 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T10141 14945-14954 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T70571 14959-14967 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T7887 15092-15097 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T231 15098-15101 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T29743 15131-15152 http://purl.obolibrary.org/obo/CL_0000113 denotes mononuclear phagocyte
T20551 15264-15269 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T37126 15289-15294 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum
T95433 15299-15306 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys
T50434 15299-15306 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidneys
T760 15299-15306 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidneys
T65167 15356-15361 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T82044 15584-15588 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T94640 15737-15742 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T89368 15817-15823 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T84481 15824-15834 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T74943 15919-15925 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T54060 16100-16109 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T5697 16127-16136 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T18605 16157-16161 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T63442 16157-16161 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T57672 16241-16247 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T38000 16621-16630 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humanized
T70288 16742-16751 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T68687 16896-16901 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T44500 16902-16909 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primate
T8952 16976-16981 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T25639 17051-17055 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T77587 17051-17055 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T2661 17182-17190 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T26384 17204-17208 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T13152 17412-17416 http://purl.obolibrary.org/obo/GO_0005623 denotes Cell
T45733 17417-17427 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activation
T38010 17440-17447 http://purl.obolibrary.org/obo/CL_0000623 denotes NK Cell
T11301 17711-17720 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T3621 17803-17804 http://purl.obolibrary.org/obo/CLO_0001020 denotes ɑ
T320 17817-17826 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T78868 17886-17894 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T1737 18148-18153 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T84467 18231-18239 http://purl.obolibrary.org/obo/CL_0000576 denotes Monocyte
T47301 18257-18259 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T48426 18274-18282 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T52652 18288-18293 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T31933 18288-18293 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T14324 18357-18365 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T89373 18422-18427 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T45576 18445-18454 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T99791 18592-18601 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T48410 18703-18707 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T98127 18776-18781 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T99778 18868-18874 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T22254 18904-18909 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T7770 18910-18913 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T157 18914-18915 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T158 18951-18960 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T159 19283-19294 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
T160 19299-19305 http://purl.obolibrary.org/obo/UBERON_0002106 denotes spleen
T161 19648-19652 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T162 19842-19852 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T163 19891-19895 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T164 19938-19943 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T165 20172-20182 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T166 20341-20345 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T167 20341-20345 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T168 20517-20526 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T169 20698-20702 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T170 20698-20702 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T171 20779-20783 http://purl.obolibrary.org/obo/CLO_0053428 denotes Camp
T172 21213-21218 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T173 21316-21337 http://purl.obolibrary.org/obo/CL_0001065 denotes Innate Lymphoid Cells
T174 21338-21359 http://purl.obolibrary.org/obo/CL_0001065 denotes Innate lymphoid cells
T175 21361-21365 http://purl.obolibrary.org/obo/CL_0001065 denotes ILCs
T176 21394-21399 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T177 21458-21464 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T178 21481-21487 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T179 21582-21592 http://purl.obolibrary.org/obo/CL_0000623 denotes (NK) cells
T180 21622-21626 http://purl.obolibrary.org/obo/CL_0001065 denotes ILCs
T181 21679-21683 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T182 21699-21707 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T183 21732-21740 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T184 21758-21763 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T185 21842-21850 http://purl.obolibrary.org/obo/CL_0000623 denotes NK Cells
T186 21883-21888 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T187 21883-21888 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T188 21960-21968 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T189 21987-21992 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T190 21987-21992 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T191 22143-22144 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T192 22180-22181 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 22211-22219 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T194 22252-22257 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T195 22328-22332 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T196 22328-22332 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T197 22333-22341 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T198 22419-22422 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T199 22445-22452 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T200 22507-22511 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T201 22545-22547 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T202 22586-22591 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T203 22592-22596 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T204 22592-22596 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T205 22651-22660 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T206 22681-22686 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T207 22783-22790 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T208 22823-22828 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T209 22823-22828 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T210 22836-22841 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T211 22876-22883 http://purl.obolibrary.org/obo/CL_0000623 denotes NK Cell
T212 22884-22894 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activation
T213 22926-22934 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T214 22958-22968 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T215 23060-23065 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T216 23075-23080 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T217 23097-23102 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T218 23187-23194 http://purl.obolibrary.org/obo/CL_0000623 denotes NK-cell
T219 23195-23205 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T220 23423-23428 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T221 23485-23492 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T222 23493-23503 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T223 23647-23654 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T224 23655-23665 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T225 23674-23676 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T226 23767-23772 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T227 23892-23900 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T228 23923-23928 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T229 24238-24245 http://purl.obolibrary.org/obo/NCBITaxon_10026 denotes hamster
T230 24246-24251 http://www.ebi.ac.uk/efo/EFO_0000973 denotes ovary
T99383 24253-24256 http://purl.obolibrary.org/obo/CLO_0002421 denotes CHO
T232 24253-24256 http://purl.obolibrary.org/obo/CLO_0052479 denotes CHO
T233 24253-24256 http://purl.obolibrary.org/obo/CLO_0052480 denotes CHO
T234 24253-24256 http://purl.obolibrary.org/obo/CLO_0052483 denotes CHO
T235 24253-24256 http://purl.obolibrary.org/obo/CLO_0052484 denotes CHO
T236 24253-24256 http://purl.obolibrary.org/obo/CLO_0052485 denotes CHO
T237 24258-24263 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T238 24325-24332 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T239 24333-24343 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T240 24466-24473 http://purl.obolibrary.org/obo/CL_0000623 denotes NK Cell
T241 24515-24523 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T242 24540-24545 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T243 24540-24545 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T244 24632-24633 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T245 24852-24860 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T246 24878-24883 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T247 24892-24900 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T248 24943-24947 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T249 24943-24947 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T250 24948-24956 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T251 25121-25129 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T252 25139-25144 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T253 25145-25149 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T254 25145-25149 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T255 25158-25159 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T256 25217-25221 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T257 25258-25263 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T258 25307-25309 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T259 25319-25328 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T260 25342-25343 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T261 25379-25384 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T262 25379-25384 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T263 25482-25489 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T264 25550-25557 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T265 25653-25661 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T266 25711-25716 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T267 25711-25716 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T268 25940-25948 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T269 25958-25963 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T270 26069-26077 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T271 26082-26085 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T272 26086-26093 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T273 26155-26159 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T274 26359-26363 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T275 26366-26371 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Genes
T276 26444-26452 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T277 26557-26565 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T278 26644-26650 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T279 26738-26745 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T280 26851-26854 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T281 26927-26928 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T282 26958-26966 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T283 27098-27104 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T284 27204-27209 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T285 27204-27209 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T286 27239-27247 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T287 27294-27302 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T288 27355-27362 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T289 27499-27506 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T290 27521-27524 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T291 27600-27609 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T292 27623-27630 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T293 27678-27683 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T294 27723-27732 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T295 27754-27761 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T296 27827-27831 http://purl.obolibrary.org/obo/CL_0001065 denotes ILCs
T297 27987-27991 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T298 27987-27991 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T299 28082-28086 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T300 28082-28086 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T301 28183-28189 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T302 28190-28200 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T303 28339-28343 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T304 28339-28343 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T305 28366-28372 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T306 28419-28423 http://purl.obolibrary.org/obo/CL_0001065 denotes ILCs
T307 28496-28497 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T308 28498-28500 http://purl.obolibrary.org/obo/CLO_0007448 denotes M1
T309 28498-28500 http://purl.obolibrary.org/obo/CLO_0050175 denotes M1
T310 28535-28536 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T311 28747-28751 http://purl.obolibrary.org/obo/CL_0001065 denotes ILCs
T312 28809-28815 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T313 28826-28833 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T314 28839-28840 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T315 28879-28882 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T316 28883-28890 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T317 28899-28905 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T318 28980-28985 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T319 28995-28998 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T61712 28999-29006 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T321 29021-29026 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T322 29077-29083 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T323 29158-29164 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T324 29282-29289 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T325 29301-29306 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T326 29383-29390 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T327 29536-29539 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T328 29544-29547 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T329 29548-29554 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T330 29576-29581 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T331 29576-29581 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T332 29765-29768 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T333 29773-29776 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T334 29777-29784 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T335 29980-29983 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T336 29984-29991 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T337 30387-30393 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T338 30471-30477 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T339 30522-30523 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T340 30623-30630 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T341 30676-30679 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T342 30726-30732 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T343 30780-30785 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T344 30780-30785 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T345 30786-30792 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T346 30819-30820 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T347 30844-30849 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T348 30844-30849 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T349 30850-30857 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T350 30988-30997 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T351 30998-31001 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T352 31006-31009 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T353 31010-31017 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T354 31033-31034 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T355 31297-31300 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T356 31301-31308 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T357 31309-31312 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T358 31418-31423 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T359 31433-31439 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T360 31469-31474 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T361 31469-31474 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T362 31636-31642 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T363 31779-31780 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T364 31791-31792 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T365 31802-31803 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T366 31883-31890 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T367 31898-31903 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T368 31898-31903 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T369 32136-32142 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T370 32359-32365 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T371 32383-32388 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T372 32383-32388 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T373 32415-32430 http://purl.obolibrary.org/obo/UBERON_0004177 denotes lymphoid organs
T374 32449-32460 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T375 32549-32556 http://purl.obolibrary.org/obo/UBERON_0002106 denotes spleens
T376 32567-32578 http://purl.obolibrary.org/obo/UBERON_0000029 denotes lymph nodes
T377 32653-32657 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T378 32944-32950 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T379 33034-33039 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T380 33034-33039 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T381 33155-33158 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T382 33159-33165 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T383 33257-33258 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T384 33368-33373 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T385 33700-33706 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T386 33765-33771 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T387 33872-33878 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T388 33980-33983 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T389 33984-33990 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T390 34040-34042 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T391 34040-34042 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T392 34123-34126 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T393 34134-34141 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T394 34159-34162 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T395 34170-34177 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T396 34183-34188 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T397 34198-34205 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T398 34231-34233 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T399 34257-34264 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T400 34396-34401 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T401 34411-34414 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T402 34415-34421 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T403 34459-34460 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T404 34540-34544 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T405 34582-34584 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T406 34582-34584 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T407 34624-34627 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T408 34628-34634 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T409 34778-34784 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T410 34872-34878 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T411 35067-35069 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T412 35067-35069 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T413 35134-35141 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T414 35221-35222 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T415 35399-35404 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T416 35414-35417 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T417 35422-35425 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T418 35426-35433 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T419 35561-35567 http://purl.obolibrary.org/obo/PR_000001015 denotes CD45RA
T420 35572-35576 http://purl.obolibrary.org/obo/PR_000001203 denotes CCR7
T421 35615-35620 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T422 35645-35648 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T423 35673-35676 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T424 35730-35735 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T425 35794-35801 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T426 36024-36025 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T427 36059-36062 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T428 36067-36070 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T429 36071-36078 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T430 36200-36201 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T431 36262-36269 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T432 36281-36285 http://purl.obolibrary.org/obo/PR_000001343 denotes CD69
T433 36342-36345 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T434 36346-36353 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T435 36404-36422 http://purl.obolibrary.org/obo/CL_0000815 denotes regulatory T cells
T436 36424-36428 http://purl.obolibrary.org/obo/CL_0000792 denotes Treg
T437 36492-36499 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T438 36560-36564 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T439 36631-36633 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T440 36635-36636 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T441 36650-36657 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T442 36672-36675 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T443 36676-36682 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T444 36696-36698 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T445 36766-36773 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T446 36825-36826 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T447 36849-36852 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T448 36853-36860 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T449 36867-36872 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T450 36930-36934 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T451 36994-37004 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T452 37092-37095 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T453 37096-37103 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T454 37107-37109 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T455 37177-37180 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T456 37181-37188 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T457 37218-37228 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T458 37316-37321 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T459 37358-37361 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T460 37369-37376 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T461 37450-37451 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T462 37615-37618 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T463 37619-37626 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T464 37923-37930 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T465 38038-38043 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T466 38038-38043 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T467 38081-38088 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T468 38171-38172 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T469 38251-38258 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T470 38413-38419 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T471 38493-38499 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T472 38543-38548 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T473 38571-38577 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T474 38703-38704 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T475 38742-38743 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T476 38805-38808 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T477 38809-38816 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T478 38953-38956 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T479 38957-38964 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T480 39134-39137 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T481 39138-39145 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T482 39283-39287 http://purl.obolibrary.org/obo/CL_0000792 denotes Treg
T483 39288-39293 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T484 39365-39369 http://purl.obolibrary.org/obo/CL_0000792 denotes Treg
T485 39370-39375 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T486 39429-39434 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T487 39458-39462 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T488 39465-39466 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T489 39475-39480 http://purl.obolibrary.org/obo/CL_0000792 denotes Tregs
T490 39526-39530 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T491 39526-39530 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T492 39559-39560 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T493 39577-39584 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T494 39586-39587 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T495 39598-39605 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T496 39687-39691 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T497 39714-39717 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T498 39833-39839 http://purl.obolibrary.org/obo/CL_0000084 denotes T Cell
T499 39933-39939 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T500 40007-40011 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T501 40007-40011 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T502 40073-40082 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T503 40083-40090 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T504 40141-40145 http://purl.obolibrary.org/obo/PR_000001408 denotes CD38
T505 40147-40151 http://purl.obolibrary.org/obo/PR_000001343 denotes CD69
T506 40153-40157 http://purl.obolibrary.org/obo/PR_000001380 denotes CD25
T507 40159-40163 http://purl.obolibrary.org/obo/PR_000001307 denotes CD44
T508 40370-40373 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T509 40374-40381 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T510 40398-40407 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T511 40413-40416 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T512 40417-40424 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T513 40490-40491 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T514 40521-40524 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T515 40530-40533 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T516 40534-40540 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T517 40570-40572 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T518 40570-40572 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T519 40604-40605 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T520 40808-40814 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T521 40898-40907 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T522 40938-40947 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T523 40948-40964 http://purl.obolibrary.org/obo/CL_0000911 denotes effector T cells
T524 40978-40982 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T525 41138-41144 http://purl.obolibrary.org/obo/PR_000001852 denotes CTLA-4
T526 41236-41239 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T527 41240-41247 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T528 41312-41315 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T529 41316-41323 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T530 41443-41446 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T531 41455-41458 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T532 41459-41466 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T533 41631-41634 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T534 41639-41642 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T535 41643-41650 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T536 41722-41729 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T537 41996-41999 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T538 42000-42007 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T539 42114-42115 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T540 42170-42171 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T541 42240-42243 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T542 42244-42251 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T543 42361-42362 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T544 42506-42513 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T545 42520-42523 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T546 42524-42531 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T547 42565-42569 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T548 42574-42577 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T549 42578-42585 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T550 42641-42643 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T551 42641-42643 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T552 42705-42711 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T553 42921-42924 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T554 42925-42932 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T555 42996-43001 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T556 43130-43137 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T557 43173-43182 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T558 43199-43200 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T559 43448-43451 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T560 43452-43459 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T561 43578-43579 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T562 43704-43705 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T563 43725-43731 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T564 43904-43910 http://purl.obolibrary.org/obo/CL_0000236 denotes B Cell
T565 43928-43934 http://purl.obolibrary.org/obo/CL_0000236 denotes B Cell
T566 44030-44037 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T567 44045-44046 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T568 44127-44128 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T569 44136-44142 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T570 44211-44216 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T571 44629-44634 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T572 45107-45112 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T573 45233-45239 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T574 45401-45407 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T575 45514-45520 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T576 45655-45660 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T577 46045-46052 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T578 46177-46181 http://purl.obolibrary.org/obo/CLO_0053432 denotes CD19
T579 46194-46201 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T580 46214-46218 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T581 46231-46232 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T582 46354-46358 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T583 46461-46462 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T584 46911-46916 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T585 46984-46990 http://purl.obolibrary.org/obo/CL_0000236 denotes B Cell
T586 47028-47034 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T587 47047-47048 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T588 47049-47054 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T589 47205-47217 http://purl.obolibrary.org/obo/CL_0000786 denotes plasma cells
T590 47340-47347 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T591 47420-47423 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T592 47427-47433 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T593 47449-47456 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T594 47480-47481 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T595 47526-47538 http://purl.obolibrary.org/obo/CL_0000786 denotes plasma cells
T596 47609-47621 http://purl.obolibrary.org/obo/CL_0000786 denotes plasma cells
T597 47633-47640 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T598 47699-47705 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T599 47766-47769 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T600 47880-47890 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T601 48021-48022 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T602 48071-48077 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T603 48142-48143 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T604 48158-48159 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T605 48230-48235 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T606 48299-48313 http://purl.obolibrary.org/obo/CL_0000912 denotes T helper cells
T607 48320-48325 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T608 48357-48358 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T609 48448-48449 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T610 48450-48461 http://purl.obolibrary.org/obo/CL_0000786 denotes plasma cell
T611 48517-48522 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T612 48571-48576 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T613 48571-48576 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T614 48687-48688 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T615 48729-48744 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T616 49038-49043 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T617 49069-49074 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T618 49163-49164 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T619 49550-49551 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T620 49578-49580 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T621 49625-49626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T51993 49658-49663 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T623 49743-49748 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T624 49884-49890 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T625 50208-50215 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T626 50217-50218 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T627 50280-50285 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T628 50359-50366 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T629 50461-50462 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T630 50574-50581 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T631 50661-50667 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T632 50822-50827 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T633 51026-51027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T634 51165-51171 http://purl.obolibrary.org/obo/CL_0000236 denotes B Cell
T635 51256-51261 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T636 51347-51352 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T637 51521-51522 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T638 51655-51657 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T639 51655-51657 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T640 51749-51750 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T641 52045-52048 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T642 52098-52105 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T643 52247-52252 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T644 52286-52291 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T645 52307-52309 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T646 52336-52341 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T647 52372-52381 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T648 52407-52417 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T649 52427-52432 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T650 52456-52457 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T651 52487-52502 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T652 52553-52557 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T653 52553-52557 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T654 52599-52608 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T655 52632-52636 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T656 52632-52636 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T657 52762-52767 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T658 52768-52776 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T659 52853-52854 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T660 52889-52890 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T661 53648-53651 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T662 53997-53999 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T663 54538-54539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T664 54546-54551 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T665 54745-54748 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T666 54813-54818 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T667 54813-54818 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T668 54841-54842 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T669 54969-54974 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T670 54969-54974 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T671 54981-54982 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T672 55005-55006 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T673 55063-55064 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T674 55065-55070 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T675 55065-55070 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T676 55079-55084 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T677 55079-55084 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T678 55274-55281 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T679 55489-55494 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T680 55955-55960 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T681 56053-56059 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T682 56190-56197 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T683 56264-56269 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T684 56357-56366 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T685 56597-56601 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T686 57264-57265 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T687 57266-57270 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T688 57343-57348 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T689 57343-57348 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T690 58367-58373 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T691 58510-58515 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T692 58510-58515 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T693 59183-59184 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T694 59573-59577 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T695 59573-59577 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T696 60446-60457 http://purl.obolibrary.org/obo/PR_000007299 denotes prothrombin
T697 60468-60477 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T698 60683-60684 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T699 60743-60744 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T700 60762-60769 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T701 61144-61147 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T702 61150-61153 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T703 61160-61167 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cell
T704 61181-61184 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T705 61187-61190 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T706 61197-61205 http://purl.obolibrary.org/obo/CL_0000623 denotes NK cells
T707 61350-61357 http://purl.obolibrary.org/obo/CLO_0001914 denotes and Tim
T708 61374-61381 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T709 61398-61405 http://purl.obolibrary.org/obo/CLO_0001914 denotes and Tim
T710 61422-61429 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T711 61647-61650 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T712 61655-61658 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T713 61659-61666 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T714 61722-61727 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T715 61722-61727 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T716 61728-61737 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T717 61754-61755 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T718 61779-61788 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T719 61838-61842 http://purl.obolibrary.org/obo/PR_000002064 denotes CD68
T720 61845-61849 http://purl.obolibrary.org/obo/PR_000001438 denotes CD80
T721 62030-62039 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T722 62154-62156 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T723 62264-62265 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T724 62597-62601 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T725 62725-62729 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T726 62862-62863 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T727 62956-62961 http://purl.obolibrary.org/obo/PR_000001380 denotes IL-2R
T728 62998-62999 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T729 63168-63177 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T730 63230-63231 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T731 63239-63243 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T732 63379-63380 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T733 63504-63508 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T734 63504-63508 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T735 63562-63563 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T736 63613-63615 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T737 63635-63639 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T738 63668-63675 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T739 63715-63717 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T740 63747-63753 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T741 63863-63870 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T742 63933-63942 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T743 64029-64033 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T744 64044-64048 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T745 64219-64220 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T746 64417-64435 http://purl.obolibrary.org/obo/UBERON_0000467 denotes Organs and Systems
T747 64493-64515 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T748 64517-64524 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys
T749 64517-64524 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidneys
T750 64517-64524 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidneys
T751 64530-64536 http://www.ebi.ac.uk/efo/EFO_0000984 denotes testis
T752 64580-64586 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T753 64598-64608 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T754 64660-64665 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T755 64676-64686 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T756 64687-64692 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T757 64743-64753 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T758 64754-64759 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T759 64768-64773 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T96254 64768-64773 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T761 64821-64826 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T762 64831-64848 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T763 64902-64907 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T764 64902-64907 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T765 64994-65009 http://purl.obolibrary.org/obo/UBERON_0002108 denotes small intestine
T766 65026-65031 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colon
T767 65077-65078 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T768 65096-65103 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T769 65188-65199 http://purl.obolibrary.org/obo/PR_000007299 denotes prothrombin
T770 65212-65221 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T771 65448-65449 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T772 65950-65951 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T773 65994-65995 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T774 66237-66242 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T775 66237-66242 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T776 66370-66380 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T777 66443-66454 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T778 66459-66468 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytic
T779 66758-66763 http://purl.obolibrary.org/obo/UBERON_0000178 denotes Blood
T780 66758-66763 http://www.ebi.ac.uk/efo/EFO_0000296 denotes Blood
T781 66836-66839 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T782 66858-66859 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T783 67304-67309 http://purl.obolibrary.org/obo/PR_000001380 denotes IL-2R
T784 67311-67315 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T785 67801-67803 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T786 68370-68371 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T787 68546-68559 http://purl.obolibrary.org/obo/CL_0000912 denotes helper T cell
T788 68576-68593 http://purl.obolibrary.org/obo/CL_0000792 denotes suppressor T cell
T789 68576-68593 http://purl.obolibrary.org/obo/CL_0000815 denotes suppressor T cell
T790 68653-68659 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T791 68661-68674 http://purl.obolibrary.org/obo/CL_0000912 denotes helper T cell
T792 68680-68697 http://purl.obolibrary.org/obo/CL_0000792 denotes suppressor T cell
T793 68680-68697 http://purl.obolibrary.org/obo/CL_0000815 denotes suppressor T cell
T794 69511-69512 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T795 69793-69798 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T796 69793-69798 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T797 69931-69932 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T798 70186-70192 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T799 70206-70229 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tracts
T800 70234-70241 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys
T801 70234-70241 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidneys
T802 70234-70241 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidneys
T803 70326-70327 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T804 70469-70484 http://purl.obolibrary.org/obo/UBERON_0004177 denotes lymphoid organs
T805 70566-70567 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T806 70646-70647 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T807 70648-70653 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T808 70708-70713 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T809 70855-70861 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T810 70973-70980 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T811 71009-71010 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T812 71058-71066 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T813 71081-71086 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T814 71091-71098 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T815 71236-71240 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T816 71236-71240 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T817 71385-71386 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T818 71588-71589 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T819 71954-71959 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T820 72040-72045 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T821 72046-72052 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T822 72053-72063 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T823 72064-72069 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T824 72209-72214 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T825 72527-72528 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T826 72573-72581 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T827 72927-72935 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T828 72939-72943 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T829 72939-72943 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T830 72944-72949 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T831 73233-73234 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T832 73470-73471 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T833 73491-73495 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T834 73509-73512 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T835 73597-73603 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T836 73667-73668 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T837 73732-73747 http://purl.obolibrary.org/obo/NCBITaxon_9544 denotes rhesus macaques
T838 73842-73843 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T839 73857-73861 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T840 73857-73861 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T841 73917-73922 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T842 74170-74171 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T843 74385-74386 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T844 74422-74431 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T845 74528-74537 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomes
T846 74614-74619 http://purl.obolibrary.org/obo/PR_000001852 denotes CTLA4
T847 74634-74639 http://purl.obolibrary.org/obo/CL_0000792 denotes Tregs
T848 74664-74673 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T849 74734-74737 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T850 74871-74880 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T851 75074-75080 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T852 75278-75279 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T853 75371-75372 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T854 75476-75477 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T855 75558-75559 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T856 75755-75756 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T857 75849-75853 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T858 76022-76023 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T859 76132-76133 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T860 76155-76158 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T861 76274-76276 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T862 76274-76276 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T863 76322-76323 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T864 76541-76542 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T865 76681-76682 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T866 76767-76768 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T867 76835-76836 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T868 76995-76996 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T869 77017-77022 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T870 77139-77140 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T871 77483-77484 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T872 77734-77736 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T873 77734-77736 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T874 77753-77754 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T875 77990-77991 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T876 78174-78176 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T877 78221-78222 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T878 78353-78356 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T879 78459-78462 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T880 79108-79117 http://purl.obolibrary.org/obo/GO_0005764 denotes lysosomal
T881 79118-79126 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T882 79312-79320 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T883 79324-79342 http://purl.obolibrary.org/obo/CL_0000815 denotes regulatory T cells
T884 79509-79514 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T885 79702-79705 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T886 79905-79910 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T887 80319-80320 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T888 80389-80393 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T889 80389-80393 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T890 80525-80529 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T891 80545-80550 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T892 81002-81003 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T893 81011-81014 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T894 81021-81026 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T895 81218-81219 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T896 81309-81310 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T897 81474-81478 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T898 81690-81691 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T899 81809-81810 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T900 81861-81864 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T901 82086-82089 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T902 82094-82095 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T903 82408-82413 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T904 82555-82560 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T905 82816-82819 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T906 83039-83040 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T907 83276-83277 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T908 83299-83301 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T909 83468-83469 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T910 83778-83781 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T911 84143-84144 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T912 84183-84185 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T913 84451-84459 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T914 84670-84671 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T915 84707-84712 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T916 84714-84715 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T917 84887-84888 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T918 85045-85046 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T919 85396-85408 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T920 86189-86190 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T921 86382-86383 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T922 86724-86725 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T923 86882-86887 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T924 87415-87417 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T925 87505-87507 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T51106 87630-87635 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T927 87653-87660 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T928 87814-87823 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T929 87879-87889 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T930 87900-87905 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T931 87995-88002 http://purl.obolibrary.org/obo/SO_0000418 denotes signals
T932 88013-88023 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T933 88024-88029 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T934 88045-88046 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T935 88073-88078 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T936 88146-88155 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T937 88169-88170 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T938 88310-88313 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T939 88319-88320 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T940 88881-88882 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T941 88991-88992 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T942 89062-89071 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T943 89341-89348 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T944 89912-89913 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T945 89957-89964 http://purl.obolibrary.org/obo/SO_0000418 denotes signals
T946 90343-90346 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T947 90347-90354 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T948 90578-90582 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T949 90642-90643 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T950 90775-90779 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T951 90800-90809 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T952 91150-91159 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T953 91185-91186 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T954 91234-91240 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T955 91442-91443 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T956 91533-91542 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T957 91777-91783 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T958 91902-91905 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T959 91940-91941 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T960 91986-91987 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T961 92245-92249 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T962 92245-92249 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T963 92284-92289 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T964 92436-92437 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T965 93485-93494 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T966 93722-93732 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T967 93766-93771 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T968 94016-94022 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T969 94090-94091 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T970 94101-94114 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T971 94214-94215 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T972 94264-94267 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T973 94648-94654 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T974 94975-94982 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T975 95523-95525 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T976 95619-95620 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T977 95695-95696 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T978 95891-95892 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T979 95957-95958 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T980 95959-95968 http://purl.obolibrary.org/obo/CLO_0036932 denotes hybridoma
T981 95979-95980 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T982 96042-96043 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T983 96156-96157 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T984 96325-96326 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T985 96367-96373 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T986 96492-96493 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T987 96549-96556 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T988 96798-96799 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T989 97479-97484 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T990 97543-97548 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T991 97628-97633 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T992 97718-97723 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T993 97799-97805 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T994 97826-97828 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T995 97877-97879 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T996 97892-97897 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T997 97923-97933 http://purl.obolibrary.org/obo/CLO_0036932 denotes hybridomas
T998 98002-98004 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T999 98007-98009 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1000 98083-98088 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T1001 98106-98107 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1002 98157-98159 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1003 98169-98171 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1004 98185-98186 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1005 98206-98208 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T1006 98206-98208 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T1007 98227-98229 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1008 98239-98241 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1009 98255-98256 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1010 98257-98259 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T1011 98257-98259 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T1012 98280-98282 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T1013 98283-98288 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1014 98380-98381 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1015 98393-98398 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1016 98406-98407 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1017 98410-98411 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1018 98461-98466 http://purl.obolibrary.org/obo/NCBITaxon_9796 denotes horse
T1019 98484-98485 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1020 98486-98489 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes Pan
T1021 98505-98506 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T1022 98541-98548 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes Animals
T1023 98549-98555 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes Animal
T1024 98669-98670 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1025 98694-98699 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1026 98749-98750 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1027 98944-98945 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T1028 98946-98951 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T1029 98952-98954 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1030 99023-99025 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1031 99080-99089 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humanized
T1032 99099-99104 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T1033 99212-99217 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T1034 99258-99265 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T1035 99342-99348 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T1036 99620-99622 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1037 99745-99747 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1038 99779-99781 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T1039 99783-99785 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T1040 99783-99785 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T1041 99886-99892 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 2143-2154 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T2 2232-2234 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T3 3926-3935 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T4 4492-4511 Chemical denotes double-stranded RNA http://purl.obolibrary.org/obo/CHEBI_67208
T5 4513-4518 Chemical denotes dsRNA http://purl.obolibrary.org/obo/CHEBI_67208
T6 4790-4799 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T7 4876-4881 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T8 4910-4912 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T10 4917-4919 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T12 4927-4929 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T14 4974-4983 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T15 5558-5565 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T16 5645-5652 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T17 5776-5784 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T18 7049-7059 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T19 7289-7294 Chemical denotes dsRNA http://purl.obolibrary.org/obo/CHEBI_67208
T20 7745-7750 Chemical denotes dsRNA http://purl.obolibrary.org/obo/CHEBI_67208
T21 7898-7907 Chemical denotes guanosine http://purl.obolibrary.org/obo/CHEBI_16750
T22 7967-7975 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T23 8447-8454 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
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T26 8942-8945 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T27 9222-9224 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T30 9236-9246 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T31 9438-9446 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T32 9511-9519 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T33 9957-9964 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
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T35 10113-10116 Chemical denotes PLP http://purl.obolibrary.org/obo/CHEBI_18405
T36 10246-10248 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T39 10277-10285 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
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T41 10609-10618 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T42 10697-10705 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T43 10829-10837 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T44 12091-12101 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T45 12387-12395 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T46 12536-12538 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T48 12546-12548 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T50 12664-12666 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T52 12673-12675 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T54 12739-12741 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T57 12756-12758 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T58 13038-13047 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T59 13932-13934 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T60 14177-14179 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T62 14205-14208 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T63 14242-14252 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T64 14253-14260 Chemical denotes mitogen http://purl.obolibrary.org/obo/CHEBI_52290
T65 14271-14278 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T66 14353-14355 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T68 14483-14485 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T70 15154-15157 Chemical denotes MNP http://purl.obolibrary.org/obo/CHEBI_139554
T71 16224-16231 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T72 17204-17206 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T74 17551-17553 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T76 17557-17559 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T78 17790-17792 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T80 18248-18253 Chemical denotes CXCL9 http://purl.obolibrary.org/obo/CHEBI_138154
T81 18329-18338 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T82 18538-18550 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T83 18545-18550 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T85 19259-19266 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T86 19367-19369 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T88 19461-19463 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T90 19598-19600 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T92 19648-19650 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T94 19654-19656 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T96 19671-19673 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T97 19769-19773 Chemical denotes MNPs http://purl.obolibrary.org/obo/CHEBI_139554
T98 19780-19782 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T100 19922-19930 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T101 21294-21303 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T102 21385-21393 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T103 21439-21446 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T104 22530-22537 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T105 22539-22544 Chemical denotes CXCL9 http://purl.obolibrary.org/obo/CHEBI_138154
T106 22634-22640 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T107 23111-23119 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T108 23149-23156 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T109 23392-23399 Chemical denotes ligands http://purl.obolibrary.org/obo/CHEBI_52214
T110 23736-23744 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T111 24195-24207 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T112 25274-25281 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T113 26208-26216 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T114 26669-26671 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T116 26820-26822 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T118 26837-26839 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T120 26952-26957 Chemical denotes donor http://purl.obolibrary.org/obo/CHEBI_17891
T121 27012-27023 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T122 27025-27027 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T124 27153-27159 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T125 27304-27307 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T126 27491-27493 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T128 27710-27712 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T130 28205-28211 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T131 28278-28280 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T133 28498-28500 Chemical denotes M1 http://purl.obolibrary.org/obo/CHEBI_51079|http://purl.obolibrary.org/obo/CHEBI_139019|http://purl.obolibrary.org/obo/CHEBI_140152|http://purl.obolibrary.org/obo/CHEBI_34826
T137 28537-28539 Chemical denotes M2 http://purl.obolibrary.org/obo/CHEBI_34827|http://purl.obolibrary.org/obo/CHEBI_51112
T139 28602-28604 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T141 31654-31656 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T143 31676-31686 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T144 31716-31718 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T145 32012-32014 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T147 32018-32020 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T149 32713-32715 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T151 32808-32810 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T153 32822-32832 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T154 32833-32844 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T155 33099-33102 Chemical denotes BAL http://purl.obolibrary.org/obo/CHEBI_64198
T156 33930-33938 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T157 34031-34038 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T158 34040-34042 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T159 34546-34548 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T161 34552-34554 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T163 34558-34560 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T165 34582-34584 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T166 34920-34928 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T167 35067-35069 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T168 35200-35202 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112
T169 35682-35690 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T170 35710-35718 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T171 35726-35728 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T172 35794-35801 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T173 35872-35879 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T174 35929-35931 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T175 35972-35980 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T176 35985-35992 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T177 36085-36092 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T178 36475-36482 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T179 36560-36562 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T181 36598-36600 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T183 36604-36606 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T185 36611-36613 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T187 36617-36619 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T189 36628-36630 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T191 36766-36773 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T192 36839-36848 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T193 36940-36942 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T194 37264-37271 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T195 38077-38080 Chemical denotes BAL http://purl.obolibrary.org/obo/CHEBI_64198
T196 38797-38799 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T197 38847-38849 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T199 38945-38947 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T200 39126-39128 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T201 39631-39640 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T202 39768-39771 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T203 40137-40139 Chemical denotes DR http://purl.obolibrary.org/obo/CHEBI_73445
T204 40196-40198 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112
T205 40213-40216 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T206 40570-40572 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T207 40676-40678 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T208 40764-40766 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T209 40865-40867 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T210 40948-40956 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
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T212 41300-41302 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T213 41848-41855 Chemical denotes phorbol http://purl.obolibrary.org/obo/CHEBI_8116
T214 41856-41865 Chemical denotes myristate http://purl.obolibrary.org/obo/CHEBI_30807
T215 41866-41873 Chemical denotes acetate http://purl.obolibrary.org/obo/CHEBI_30089|http://purl.obolibrary.org/obo/CHEBI_47622
T217 41875-41878 Chemical denotes PMA http://purl.obolibrary.org/obo/CHEBI_37537|http://purl.obolibrary.org/obo/CHEBI_53780|http://purl.obolibrary.org/obo/CHEBI_60755
T220 41884-41893 Chemical denotes ionomycin http://purl.obolibrary.org/obo/CHEBI_63954
T221 42053-42061 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
T222 42380-42385 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T223 42565-42567 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T225 42641-42643 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T226 42940-42943 Chemical denotes BAL http://purl.obolibrary.org/obo/CHEBI_64198
T227 43286-43288 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T228 43547-43555 Chemical denotes effector http://purl.obolibrary.org/obo/CHEBI_35224
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T231 44867-44879 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T232 45002-45009 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T233 45350-45358 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T234 45377-45384 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T235 48474-48477 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T236 49788-49791 Chemical denotes Guo http://purl.obolibrary.org/obo/CHEBI_16750
T35841 49979-49986 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T71759 50252-50259 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58324 51655-51657 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T89931 53929-53936 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T85513 54819-54824 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T35249 54975-54980 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T1068 55085-55090 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T22429 56349-56356 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T9 57711-57719 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T87618 57748-57755 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T11 57772-57779 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30523 58011-58013 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T86952 58073-58077 Chemical denotes urea http://purl.obolibrary.org/obo/CHEBI_16199
T22214 58079-58089 Chemical denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T32726 58110-58119 Chemical denotes bilirubin http://purl.obolibrary.org/obo/CHEBI_16990
T93079 59456-59465 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163
T80180 60762-60769 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T44665 61345-61347 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T10664 61393-61395 Chemical denotes PD http://purl.obolibrary.org/obo/CHEBI_74756
T42987 61886-61888 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T62277 61892-61894 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T25505 62024-62026 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T7879 62092-62097 Chemical denotes IP-10 http://purl.obolibrary.org/obo/CHEBI_138157
T28 62092-62094 Chemical denotes IP http://purl.obolibrary.org/obo/CHEBI_74076
T29 62099-62102 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T91847 62110-62112 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T46613 62117-62122 Chemical denotes IP-10 http://purl.obolibrary.org/obo/CHEBI_138157
T39459 62117-62119 Chemical denotes IP http://purl.obolibrary.org/obo/CHEBI_74076
T9315 62124-62127 Chemical denotes MCP http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099
T37 62135-62137 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T51658 62309-62311 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T54106 62597-62599 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T25821 62725-62727 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T24408 62738-62740 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T47 62956-62958 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T49 63150-63152 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T51 63161-63163 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T53 63330-63332 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T55 63465-63467 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T88508 63470-63472 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T55493 63610-63612 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T61 63712-63714 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T15544 63842-63844 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T25513 63849-63851 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T38568 63925-63927 Chemical denotes GM http://purl.obolibrary.org/obo/CHEBI_74120
T49266 64029-64031 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T1095 64044-64046 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T49020 65039-65050 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T9385 65072-65075 Chemical denotes BNP http://purl.obolibrary.org/obo/CHEBI_80234
T32155 65096-65103 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T73 65121-65128 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34446 65130-65132 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T67041 65184-65186 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T77 65839-65846 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T69698 67046-67048 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
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T51573 102157-102159 Chemical denotes CP http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461
T93279 103049-103051 Chemical denotes CP http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461
T45381 103286-103288 Chemical denotes CP http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461
T8401 104130-104137 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T86519 104495-104502 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T57903 104561-104568 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30408 104695-104702 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T21639 104991-104998 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T40595 105276-105283 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T85931 105314-105322 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T55851 105596-105598 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112
T49065 105699-105706 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T38 105858-105866 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T96826 106066-106068 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T23755 106114-106123 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T13400 106281-106283 Chemical denotes Ni http://purl.obolibrary.org/obo/CHEBI_28112
T50430 106367-106374 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T25409 106464-106471 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T90657 106493-106501 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T83746 106776-106784 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T81019 106829-106836 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T98403 107110-107117 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30623 107163-107170 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T56251 107198-107206 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T69460 107458-107465 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58496 107558-107561 Chemical denotes Lin http://purl.obolibrary.org/obo/CHEBI_32386
T83392 108141-108148 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T48814 108411-108418 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T98496 109119-109126 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T58596 109355-109357 Chemical denotes SE http://purl.obolibrary.org/obo/CHEBI_74813
T56 109390-109393 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T77516 109420-109427 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T87436 109575-109582 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T71612 109682-109684 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T31898 109736-109743 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T15035 109847-109849 Chemical denotes LV http://purl.obolibrary.org/obo/CHEBI_73579
T54605 109947-109955 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T91585 110124-110132 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T38960 110243-110250 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T99016 110460-110467 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T31789 110468-110480 Chemical denotes nanoparticle http://purl.obolibrary.org/obo/CHEBI_50803
T67 110514-110522 Chemical denotes adjuvant http://purl.obolibrary.org/obo/CHEBI_60809
T43172 110561-110568 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T69 110731-110736 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T23115 110737-110749 Chemical denotes nanoparticle http://purl.obolibrary.org/obo/CHEBI_50803
T4566 112627-112631 Chemical denotes cGMP http://purl.obolibrary.org/obo/CHEBI_16356
T20723 115889-115892 Chemical denotes Lin http://purl.obolibrary.org/obo/CHEBI_32386
T99834 116965-116967 Chemical denotes MD http://purl.obolibrary.org/obo/CHEBI_74699
T22358 117469-117473 Chemical denotes Neon http://purl.obolibrary.org/obo/CHEBI_33310
T75 117807-117814 Chemical denotes Celsius http://purl.obolibrary.org/obo/CHEBI_145500

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1853-1862 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 2415-2425 Phenotype denotes mild fever http://purl.obolibrary.org/obo/HP_0011134
T3 2427-2432 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T4 2438-2445 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T5 2449-2463 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T6 2465-2484 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T7 3036-3044 Phenotype denotes plethora http://purl.obolibrary.org/obo/HP_0001050
T8 4854-4859 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T9 12847-12861 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T10 13595-13615 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T11 13633-13658 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041
T12 13669-13680 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T13 15926-15942 Phenotype denotes hypersensitivity http://purl.obolibrary.org/obo/HP_0041092
T14 16694-16703 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T15 17045-17062 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T16 24032-24037 Phenotype denotes Moody http://purl.obolibrary.org/obo/HP_0001575
T17 24427-24441 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T18 29712-29723 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T19 29950-29961 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T20 31693-31698 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T21 31865-31890 Phenotype denotes reduced number of T cells http://purl.obolibrary.org/obo/HP_0005403
T22 31970-31981 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T23 33642-33653 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T24 39013-39032 Phenotype denotes autoimmune diseases http://purl.obolibrary.org/obo/HP_0002960
T25 39064-39093 Phenotype denotes juvenile rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0005681
T26 39196-39202 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T27 39663-39672 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T28 52547-52564 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T29 52566-52569 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T30 59250-59259 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T31 59270-59279 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T32 60204-60242 Phenotype denotes disseminated intravascular coagulation http://purl.obolibrary.org/obo/HP_0005521
T33 60989-61005 Phenotype denotes Thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T34 62556-62575 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T35 63295-63309 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T36 65251-65262 Phenotype denotes Lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T37 66523-66539 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T38 66544-66560 Phenotype denotes elevated D-dimer http://purl.obolibrary.org/obo/HP_0033106
T39 66595-66609 Phenotype denotes coagulopathies http://purl.obolibrary.org/obo/HP_0003256
T40 67192-67211 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T41 68099-68118 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T42 69714-69725 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T43 69799-69817 Phenotype denotes hypercoagulability http://purl.obolibrary.org/obo/HP_0100724
T44 69882-69908 Phenotype denotes cytokine release syndromes http://purl.obolibrary.org/obo/HP_0033041
T45 70432-70443 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T46 73878-73887 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T47 78021-78028 Phenotype denotes Allergy http://purl.obolibrary.org/obo/HP_0012393
T48 82361-82366 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T49 84520-84534 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T50 86900-86905 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T51 89828-89842 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T52 90211-90225 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T53 90311-90322 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T54 90888-90902 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T55 91826-91835 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T56 92400-92420 Phenotype denotes pulmonary infections http://purl.obolibrary.org/obo/HP_0006532
T57 92625-92634 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T58 102620-102635 Phenotype denotes lymphocytopenia http://purl.obolibrary.org/obo/HP_0001888
T59 102695-102702 Phenotype denotes viremia http://purl.obolibrary.org/obo/HP_0020071
T60 110632-110641 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115
T61 114906-114917 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T62 117221-117227 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T63 117631-117637 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 102806-102817 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T2 104745-104776 http://purl.obolibrary.org/obo/GO_0050778 denotes stimulating the immune response
T3 104761-104776 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T4 105117-105139 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T5 105117-105139 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T6 105873-105879 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T7 105949-105955 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T8 106026-106032 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T9 106050-106056 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T10 106829-106849 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen presentation
T11 111955-111960 http://purl.obolibrary.org/obo/GO_0007568 denotes aging
T12 112346-112362 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T13 114051-114067 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T14 114470-114485 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T15 114520-114536 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T99629 434-459 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T5767 1116-1141 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T554 3129-3141 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T95752 3641-3666 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T84206 4029-4051 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune response
T43781 4036-4051 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T67328 4101-4124 http://purl.obolibrary.org/obo/GO_0019048 denotes virus-host interactions
T23040 4287-4300 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T33880 4301-4310 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T30976 4654-4672 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T93366 4654-4663 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T38686 4685-4694 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T12997 4860-4868 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T91841 4860-4868 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T14950 4860-4868 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T16 4860-4868 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T17 5028-5052 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune response
T18 5037-5052 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T19 5662-5677 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T20 6081-6096 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T21 6166-6175 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T22 6865-6883 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine secretion
T23 6874-6883 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T24 6891-6910 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T25 6898-6910 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T26 6952-6974 http://purl.obolibrary.org/obo/GO_0045087 denotes Innate Immune Response
T27 6959-6974 http://purl.obolibrary.org/obo/GO_0006955 denotes Immune Response
T28 7016-7029 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T29 7060-7069 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T30 7206-7221 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immunity
T31 7817-7834 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T32 7817-7834 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T33 8105-8116 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T34 8126-8137 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T35 8259-8276 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T36 8259-8276 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T37 9137-9155 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T38 9137-9146 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T39 9172-9187 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T40 9191-9212 http://purl.obolibrary.org/obo/GO_0000981 denotes transcription factors
T41 9191-9204 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T42 9301-9314 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T43 9528-9546 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling cascades
T44 9528-9537 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T45 9595-9604 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T46 9740-9749 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T47 9815-9824 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T48 9838-9842 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T49 9896-9900 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T50 9989-9993 http://purl.obolibrary.org/obo/GO_0008384 denotes TBK1
T51 9994-10003 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T52 10149-10164 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T53 10564-10577 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T54 10582-10593 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T55 10656-10665 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T56 10735-10754 http://purl.obolibrary.org/obo/GO_0007165 denotes signal transduction
T57 10742-10754 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T58 10852-10865 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T59 10915-10926 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T60 10977-10992 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T61 11327-11342 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T62 12250-12259 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T63 12523-12532 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T64 12600-12612 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T65 12673-12688 http://purl.obolibrary.org/obo/GO_0032637 denotes IL-8 production
T66 13065-13078 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T67 13187-13211 http://purl.obolibrary.org/obo/GO_0002385 denotes Mucosal immune responses
T68 14287-14291 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T69 14300-14325 http://purl.obolibrary.org/obo/GO_0002250 denotes adaptive immune responses
T70 14945-14954 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T71 15687-15699 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T72 15817-15834 http://purl.obolibrary.org/obo/GO_0042110 denotes T cell activation
T73 15819-15834 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T74 15926-15942 http://purl.obolibrary.org/obo/GO_0002524 denotes hypersensitivity
T75 16100-16109 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T76 16393-16405 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T77 17412-17427 http://purl.obolibrary.org/obo/GO_0001775 denotes Cell Activation
T78 18028-18049 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T79 18703-18713 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T80 18809-18821 http://purl.obolibrary.org/obo/GO_0006954 denotes Inflammation
T81 18951-18960 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T82 18965-18983 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine secretion
T83 18974-18983 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T84 19751-19767 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T85 20198-20208 http://purl.obolibrary.org/obo/GO_0070269 denotes pyroptosis
T86 20423-20434 http://purl.obolibrary.org/obo/GO_0097528 denotes necroptosis
T87 20423-20434 http://purl.obolibrary.org/obo/GO_0070266 denotes necroptosis
T88 20517-20526 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T89 20765-20777 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T90 21231-21243 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T91 21294-21313 http://purl.obolibrary.org/obo/GO_0051607 denotes antiviral responses
T92 21371-21384 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune
T93 21790-21809 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T94 22876-22894 http://purl.obolibrary.org/obo/GO_0030101 denotes NK Cell Activation
T95 23051-23056 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T96 23485-23503 http://purl.obolibrary.org/obo/GO_0030101 denotes NK cell activation
T97 23488-23503 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T98 23534-23543 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T99 23647-23665 http://purl.obolibrary.org/obo/GO_0030101 denotes NK cell activation
T100 23650-23665 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T101 23869-23888 http://purl.obolibrary.org/obo/GO_0001816 denotes cytokine production
T102 23905-23910 http://purl.obolibrary.org/obo/GO_0019835 denotes lysis
T103 23978-23982 http://purl.obolibrary.org/obo/GO_0001788 denotes ADCC
T104 24099-24103 http://purl.obolibrary.org/obo/GO_0001788 denotes ADCC
T105 24325-24343 http://purl.obolibrary.org/obo/GO_0030101 denotes NK cell activation
T106 24328-24343 http://purl.obolibrary.org/obo/GO_0001775 denotes cell activation
T107 24913-24922 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T108 24913-24922 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T109 25319-25328 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T110 25485-25501 http://purl.obolibrary.org/obo/GO_0048468 denotes cell development
T111 26918-26939 http://purl.obolibrary.org/obo/GO_0071613 denotes granzyme B production
T112 27025-27030 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6R
T113 27355-27378 http://purl.obolibrary.org/obo/GO_0001779 denotes NK cell differentiation
T114 27358-27378 http://purl.obolibrary.org/obo/GO_0030154 denotes cell differentiation
T115 27516-27520 http://purl.obolibrary.org/obo/GO_0001788 denotes ADCC
T116 27626-27642 http://purl.obolibrary.org/obo/GO_0008037 denotes cell recognition
T117 27723-27732 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T118 28861-28877 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T119 28915-28934 http://purl.obolibrary.org/obo/GO_0002377 denotes antibody production
T120 29376-29382 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T121 30558-30574 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T122 30604-30619 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T123 30895-30907 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T124 31699-31707 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T125 31699-31707 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T126 31699-31707 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T127 31699-31707 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T128 32402-32411 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T129 32653-32663 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T130 34127-34133 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T131 34163-34169 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T132 35662-35668 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T133 35691-35697 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T134 35719-35725 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T135 37362-37368 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T136 37759-37775 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T137 39413-39425 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T138 40898-40907 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T139 43962-43985 http://purl.obolibrary.org/obo/GO_0006959 denotes humoral immune response
T140 43970-43985 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T141 44065-44071 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T142 44198-44216 http://purl.obolibrary.org/obo/GO_0009597 denotes detection of virus
T143 45113-45139 http://purl.obolibrary.org/obo/GO_0051701 denotes interactions with the host
T144 46038-46044 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T145 46187-46193 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T146 46875-46907 http://purl.obolibrary.org/obo/GO_0097282 denotes antibody mediated neutralization
T147 46991-46997 http://purl.obolibrary.org/obo/GO_0007613 denotes Memory
T148 47325-47331 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T149 47333-47339 http://purl.obolibrary.org/obo/GO_0007613 denotes Memory
T150 47434-47440 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T151 47442-47448 http://purl.obolibrary.org/obo/GO_0007613 denotes Memory
T152 47626-47632 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T153 47706-47712 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T154 48078-48084 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T155 48510-48516 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T156 48966-48982 http://purl.obolibrary.org/obo/GO_0007616 denotes long-term memory
T157 48976-48982 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T158 50201-50207 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T159 50273-50279 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T160 50352-50358 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T161 50567-50573 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T162 50654-50660 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T163 56597-56612 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T164 57902-57918 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T165 58091-58099 http://purl.obolibrary.org/obo/GO_0004869 denotes cystatin
T166 60086-60097 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T167 60231-60242 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T168 60372-60383 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T169 60411-60422 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T170 62110-62116 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1ra
T171 62135-62141 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1ra
T172 62956-62961 http://purl.obolibrary.org/obo/GO_0004911 denotes IL-2R
T173 66398-66409 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T174 67304-67309 http://purl.obolibrary.org/obo/GO_0004911 denotes IL-2R
T175 68013-68019 http://purl.obolibrary.org/obo/GO_0005152 denotes IL-1ra
T176 70269-70281 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T177 70788-70804 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T178 71422-71431 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T179 71464-71470 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T180 71695-71717 http://purl.obolibrary.org/obo/GO_0046114 denotes guanosine biosynthesis
T181 71705-71717 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T182 73038-73066 http://purl.obolibrary.org/obo/GO_1903901 denotes inhibiting viral replication
T183 73049-73066 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T184 73049-73066 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T185 73143-73152 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T186 73211-73228 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T187 73211-73228 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T188 73446-73459 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T189 74547-74565 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen processing
T190 74664-74681 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T191 74664-74673 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T192 79196-79214 http://purl.obolibrary.org/obo/GO_0019882 denotes antigen processing
T193 80119-80135 http://purl.obolibrary.org/obo/GO_0006955 denotes immune responses
T194 80525-80540 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T195 84679-84694 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T196 87814-87823 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T197 87934-87946 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T198 88146-88155 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T199 88224-88236 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T200 88425-88437 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T201 89062-89071 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T202 91533-91550 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T203 91533-91542 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T204 91652-91657 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6R
T205 92920-92925 http://purl.obolibrary.org/obo/GO_0004915 denotes IL-6R
T206 93485-93502 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T207 93485-93494 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T208 93565-93570 http://purl.obolibrary.org/obo/GO_0004908 denotes IL-1R
T209 93711-93732 http://purl.obolibrary.org/obo/GO_0006956 denotes complement activation
T210 94968-94974 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T211 95306-95338 http://purl.obolibrary.org/obo/GO_0097282 denotes antibody-mediated neutralization
T212 96542-96548 http://purl.obolibrary.org/obo/GO_0007613 denotes memory

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 14-22 Disease denotes COVID-19 MESH:C000657245
14 702-704 Gene denotes to Gene:6999
15 547-549 Gene denotes to Gene:6999
16 290-292 Gene denotes to Gene:6999
17 123-170 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
18 172-182 Species denotes SARS-CoV-2 Tax:2697049
19 209-215 Species denotes people Tax:9606
20 67-91 Disease denotes coronavirus disease 2019 MESH:C000657245
21 93-101 Disease denotes COVID-19 MESH:C000657245
22 335-342 Disease denotes COVID19 MESH:C000657245
23 472-492 Disease denotes SARS-CoV-2 infection MESH:C000657245
24 571-576 Disease denotes death MESH:D003643
25 722-742 Disease denotes SARS-CoV-2 infection MESH:C000657245
38 1384-1386 Gene denotes to Gene:6999
39 1229-1231 Gene denotes to Gene:6999
40 972-974 Gene denotes to Gene:6999
41 805-852 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
42 854-864 Species denotes SARS-CoV-2 Tax:2697049
43 891-897 Species denotes people Tax:9606
44 749-773 Disease denotes coronavirus disease 2019 MESH:C000657245
45 775-783 Disease denotes COVID-19 MESH:C000657245
46 1017-1024 Disease denotes COVID19 MESH:C000657245
47 1154-1174 Disease denotes SARS-CoV-2 infection MESH:C000657245
48 1253-1258 Disease denotes death MESH:D003643
49 1404-1424 Disease denotes SARS-CoV-2 infection MESH:C000657245
84 2143-2174 Gene denotes angiotensin-converting enzyme 2 Gene:59272
85 2176-2180 Gene denotes ACE2 Gene:59272
86 2532-2534 Gene denotes to Gene:6999
87 2446-2448 Gene denotes to Gene:6999
88 2412-2414 Gene denotes to Gene:6999
89 2315-2317 Gene denotes to Gene:6999
90 2109-2111 Gene denotes to Gene:6999
91 1979-1981 Gene denotes to Gene:6999
92 1774-1776 Gene denotes to Gene:6999
93 1499-1546 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
94 1548-1558 Species denotes SARS-CoV-2 Tax:2697049
95 1752-1762 Species denotes SARS-CoV-2 Tax:2697049
96 2065-2080 Species denotes betacoronavirus Tax:694002
97 2116-2129 Species denotes coronaviruses Tax:11118
98 2131-2135 Species denotes CoVs Tax:11118
99 2309-2314 Species denotes human Tax:9606
100 2318-2323 Species denotes human Tax:9606
101 2497-2507 Species denotes SARS-CoV-2 Tax:2697049
102 2563-2571 Species denotes SARS-CoV Tax:694009
103 2616-2626 Species denotes MERS) CoVs Tax:1335626
104 2734-2744 Species denotes SARS-CoV-2 Tax:2697049
105 2765-2773 Species denotes SARS-CoV Tax:694009
106 2779-2787 Species denotes MERS-CoV Tax:1335626
107 1578-1602 Disease denotes coronavirus disease 2019 MESH:C000657245
108 1604-1612 Disease denotes COVID-19 MESH:C000657245
109 1847-1862 Disease denotes viral pneumonia
110 2289-2297 Disease denotes zoonotic MESH:D015047
111 2420-2425 Disease denotes fever MESH:D005334
112 2427-2432 Disease denotes cough MESH:D003371
113 2438-2445 Disease denotes dyspnea MESH:D004417
114 2465-2484 Disease denotes respiratory failure MESH:D012131
115 2490-2495 Disease denotes death MESH:D003643
116 2579-2614 Disease denotes Middle Eastern respiratory syndrome MESH:D018352
117 2636-2644 Disease denotes zoonotic MESH:D015047
127 3667-3669 Gene denotes to Gene:6999
128 3367-3369 Gene denotes to Gene:6999
129 3106-3108 Gene denotes to Gene:6999
130 2991-2993 Gene denotes to Gene:6999
131 3670-3680 Species denotes SARS-CoV-2 Tax:2697049
132 3693-3697 Species denotes CoVs Tax:11118
133 3048-3056 Disease denotes COVID-19 MESH:C000657245
134 3145-3153 Disease denotes COVID-19 MESH:C000657245
135 3580-3588 Disease denotes COVID-19 MESH:C000657245
167 4627-4630 Gene denotes PRR Gene:10159
168 4854-4881 Gene denotes tumor necrosis factor alpha Gene:7124
169 4883-4888 Gene denotes TNF-α Gene:7124
170 4895-4908 Gene denotes interleukin-1 Gene:3552
171 4910-4914 Gene denotes IL-1 Gene:3552
172 4917-4921 Gene denotes IL-6 Gene:3569
173 4927-4932 Gene denotes IL-18 Gene:3606
174 5257-5266 Gene denotes IFN-I/III
175 5585-5589 Gene denotes LY6E Gene:4061
176 5635-5640 Gene denotes spike Gene:43740568
177 5642-5643 Gene denotes S Gene:43740568
178 5606-5608 Gene denotes to Gene:6999
179 5298-5300 Gene denotes to Gene:6999
180 5254-5256 Gene denotes to Gene:6999
181 4157-4159 Gene denotes to Gene:6999
182 4052-4054 Gene denotes to Gene:6999
183 3986-3988 Gene denotes To Gene:6999
184 3974-3976 Gene denotes to Gene:6999
185 4055-4065 Species denotes SARS-CoV-2 Tax:2697049
186 4135-4145 Species denotes SARS-CoV-2 Tax:2697049
187 4203-4207 Species denotes CoVs Tax:11118
188 4250-4254 Species denotes CoVs Tax:11118
189 4347-4357 Species denotes SARS-CoV-2 Tax:2697049
190 5230-5240 Species denotes SARS-CoV-2 Tax:2697049
191 5323-5331 Species denotes SARS-CoV Tax:694009
192 5624-5634 Species denotes SARS-CoV-2 Tax:2697049
193 5793-5803 Species denotes SARS-CoV-2 Tax:2697049
194 5831-5839 Species denotes SARS-CoV Tax:694009
195 5944-5948 Species denotes CoVs Tax:11118
196 5123-5136 Disease denotes CoV infection MESH:D018352
197 5900-5909 Disease denotes infection MESH:D007239
199 6979-6992 Species denotes Coronaviruses Tax:11118
202 7124-7132 Species denotes SARS-CoV Tax:694009
203 7139-7147 Species denotes MERS-CoV Tax:1335626
215 6664-6666 Gene denotes to Gene:6999
216 6849-6852 Gene denotes PRR Gene:10159
217 6098-6102 Species denotes CoVs Tax:11118
218 6217-6225 Species denotes SARS-CoV Tax:694009
219 6360-6370 Species denotes SARS-CoV-2 Tax:2697049
220 6523-6529 Species denotes ferret Tax:9669
221 6573-6581 Species denotes patients Tax:9606
222 6781-6785 Species denotes CoVs Tax:11118
223 6081-6096 Disease denotes viral infection MESH:D001102
224 6471-6479 Disease denotes infected MESH:D007239
225 6594-6602 Disease denotes COVID-19 MESH:C000657245
261 7385-7390 Gene denotes RIG-I Gene:23586
262 7392-7396 Gene denotes MDA5 Gene:64135
263 7402-7405 Gene denotes PKR Gene:5610
264 7452-7456 Gene denotes TLR7 Gene:51284
265 7460-7464 Gene denotes TLR8 Gene:51311
266 7481-7486 Gene denotes RIG-I Gene:23586
267 7491-7494 Gene denotes PKR Gene:5610
268 8464-8470 Gene denotes TRIM25 Gene:7706
269 8485-8490 Gene denotes RIG-I Gene:23586
270 8569-8572 Gene denotes PKR Gene:5610
271 8639-8643 Gene denotes PACT Gene:8575
272 8749-8755 Gene denotes RNaseL Gene:6041
273 8897-8900 Gene denotes PLP Gene:57026
274 9017-9019 Gene denotes to Gene:6999
275 7730-7732 Gene denotes To Gene:6999
276 7593-7596 Gene denotes PRR Gene:10159
277 7520-7523 Gene denotes PRR Gene:10159
278 7245-7248 Gene denotes PRR Gene:10159
279 8315-8319 Gene denotes MDA5 Gene:64135
280 7179-7182 Species denotes CoV Tax:11118
281 7258-7271 Species denotes ssRNA viruses Tax:439488
282 7278-7282 Species denotes CoVs Tax:11118
283 7496-7500 Species denotes CoVs Tax:11118
284 7838-7846 Species denotes SARS-CoV Tax:694009
285 7947-7951 Species denotes CoVs Tax:11118
286 8171-8175 Species denotes CoVs Tax:11118
287 8364-8368 Species denotes CoVs Tax:11118
288 8434-8442 Species denotes SARS-CoV Tax:694009
289 8520-8528 Species denotes MERS-CoV Tax:1335626
290 8723-8731 Species denotes MERS-CoV Tax:1335626
291 8864-8872 Species denotes SARS-CoV Tax:694009
292 9026-9036 Species denotes SARS-CoV-2 Tax:2697049
293 7422-7427 Chemical denotes ssRNA
294 7898-7907 Chemical denotes guanosine MESH:D006151
295 8232-8244 Chemical denotes polyuridines
329 9524-9527 Gene denotes PRR Gene:10159
330 9643-9648 Gene denotes Tom70 Gene:9868
331 9735-9739 Gene denotes MAVS Gene:57506
332 9838-9842 Gene denotes TBK1 Gene:29110
333 9873-9878 Gene denotes RNF41 Gene:10193
334 9896-9900 Gene denotes TBK1 Gene:29110
335 9905-9909 Gene denotes IRF3 Gene:3661
336 9989-9993 Gene denotes TBK1 Gene:29110
337 10049-10054 Gene denotes ORF4b Gene:14254597
338 10132-10136 Gene denotes ORF6 Gene:43740572
339 10144-10148 Gene denotes IRF3 Gene:3661
340 10352-10357 Gene denotes ORF4b Gene:14254597
341 10362-10366 Gene denotes ORF5 Gene:51503
342 10434-10438 Gene denotes NSP1 Gene:10045
343 10497-10501 Gene denotes NSP1 Gene:10045
344 10312-10315 Gene denotes PLP Gene:57026
345 10113-10116 Gene denotes PLP Gene:57026
346 9974-9976 Gene denotes to Gene:6999
347 9298-9300 Gene denotes to Gene:6999
348 9165-9167 Gene denotes to Gene:6999
349 9613-9617 Gene denotes MAVS Gene:57506
350 9427-9437 Species denotes SARS-CoV-2 Tax:2697049
351 9548-9558 Species denotes SARS-CoV-2 Tax:2697049
352 9707-9715 Species denotes SARS-CoV Tax:694009
353 9783-9793 Species denotes SARS-CoV-2 Tax:2697049
354 9944-9952 Species denotes SARS-CoV Tax:694009
355 10040-10048 Species denotes MERS-CoV Tax:1335626
356 10102-10110 Species denotes SARS-CoV Tax:694009
357 10273-10276 Species denotes CoV Tax:11118
358 10301-10309 Species denotes SARS-CoV Tax:694009
359 10343-10351 Species denotes MERS-CoV Tax:1335626
360 10423-10431 Species denotes SARS-CoV Tax:694009
361 10489-10496 Species denotes ERS-CoV Tax:1335626
377 10798-10804 Gene denotes IFNAR1 Gene:3454
378 10824-10828 Gene denotes STAT Gene:6772
379 10908-10914 Gene denotes IFNAR1 Gene:3454
380 10971-10976 Gene denotes STAT1 Gene:6772
381 10996-11000 Gene denotes NSP1 Gene:10045
382 11044-11049 Gene denotes STAT1 Gene:6772
383 11075-11079 Gene denotes ORF6 Gene:43740572
384 11155-11159 Gene denotes ORF6 Gene:43740572
385 11321-11326 Gene denotes STAT1 Gene:6772
386 11312-11314 Gene denotes to Gene:6999
387 10693-10696 Species denotes CoV Tax:11118
388 10871-10879 Species denotes SARS-CoV Tax:694009
389 11144-11154 Species denotes SARS-CoV-2 Tax:2697049
390 11285-11305 Disease denotes SARS-CoV-2 infection MESH:C000657245
391 11354-11374 Disease denotes SARS-CoV-1 infection MESH:C000657245
414 12126-12130 Gene denotes ACE2 Gene:59272
415 12536-12541 Gene denotes IL-1β Gene:3552
416 12546-12551 Gene denotes IL-18 Gene:3606
417 12636-12640 Gene denotes NSP9 Gene:43740578
418 12645-12650 Gene denotes NSP10 Gene:43740578
419 12664-12668 Gene denotes IL-6 Gene:3569
420 12673-12677 Gene denotes IL-8 Gene:3576
421 12719-12723 Gene denotes NKRF Gene:55922
422 12520-12522 Gene denotes to Gene:6999
423 12166-12168 Gene denotes to Gene:6999
424 11780-11782 Gene denotes to Gene:6999
425 11532-11536 Species denotes CoVs Tax:11118
426 11724-11732 Species denotes SARS-CoV Tax:694009
427 12235-12239 Species denotes CoVs Tax:11118
428 12356-12364 Species denotes SARS-CoV Tax:694009
429 12625-12635 Species denotes SARS-CoV-2 Tax:2697049
430 12884-12892 Species denotes patients Tax:9606
431 11669-11677 Disease denotes COVID-19 MESH:C000657245
432 11739-11757 Disease denotes MERS-CoV infection MESH:D018352
433 12600-12612 Disease denotes inflammation MESH:D007249
434 12875-12883 Disease denotes COVID-19 MESH:C000657245
435 13162-13170 Disease denotes COVID-19 MESH:C000657245
443 13491-13493 Gene denotes to Gene:6999
444 13212-13214 Gene denotes to Gene:6999
445 13494-13514 Disease denotes dysregulated myeloid MESH:D021081
446 13552-13579 Disease denotes COVID-19 hallmark syndromes MESH:C000657245
447 13589-13624 Disease denotes acute respiratory distress syndrome MESH:D012128
448 13626-13630 Disease denotes ARDS MESH:D012128
449 13669-13680 Disease denotes lymphopenia MESH:D008231
451 13732-13740 Disease denotes COVID-19 MESH:C000657245
469 13882-13930 Gene denotes granulocyte-macrophage colony-stimulating factor Gene:1437
470 13932-13938 Gene denotes GM-CSF Gene:1437
471 13961-13964 Gene denotes CD4 Gene:920
472 14177-14182 Gene denotes IL-1β Gene:3552
473 14353-14358 Gene denotes IL-1β Gene:3552
474 14483-14488 Gene denotes IL-1β Gene:3552
475 14755-14764 Gene denotes Ficolin-1 Gene:2219
476 13838-13846 Species denotes patients Tax:9606
477 14445-14453 Species denotes patients Tax:9606
478 14679-14687 Species denotes patients Tax:9606
479 13829-13837 Disease denotes COVID-19 MESH:C000657245
480 14436-14444 Disease denotes COVID-19 MESH:C000657245
481 14700-14708 Disease denotes COVID-19 MESH:C000657245
482 15056-15060 Disease denotes ARDS MESH:D012128
483 15110-15126 Disease denotes pulmonary damage MESH:D008171
484 15210-15218 Disease denotes COVID-19 MESH:C000657245
485 15407-15415 Disease denotes COVID-19 MESH:C000657245
489 15457-15465 Species denotes SARS-CoV Tax:694009
490 15469-15477 Species denotes MERS-CoV Tax:1335626
491 15483-15489 Species denotes Murine Tax:10090
493 17372-17392 Disease denotes SARS-CoV-2 Infection MESH:C000657245
496 17536-17549 Species denotes coronaviruses Tax:11118
497 17488-17496 Disease denotes COVID-19 MESH:C000657245
508 17551-17555 Gene denotes IL-6 Gene:3569
509 17557-17562 Gene denotes IL-1β Gene:3552
510 17790-17794 Gene denotes IL-6 Gene:3569
511 17799-17804 Gene denotes TNF-ɑ Gene:7124
512 18248-18259 Gene denotes CXCL9/10/11 Gene:4283
513 17583-17591 Disease denotes infected MESH:D007239
514 17927-17940 Disease denotes dysfunctional MESH:D009461
515 18061-18101 Disease denotes neutrophilic NETosis and microthrombosis MESH:C564275
516 18115-18123 Disease denotes COVID-19 MESH:C000657245
517 18408-18421 Disease denotes SARS-infected MESH:D045169
526 18504-18508 Gene denotes Arg1 Gene:383
527 18510-18520 Gene denotes arginase 1 Gene:383
528 18522-18526 Gene denotes iNOS Gene:4843
529 18603-18607 Gene denotes Macs Gene:4082
530 18487-18489 Gene denotes to Gene:6999
531 18664-18671 Disease denotes NETosis
532 18708-18713 Disease denotes death MESH:D003643
533 18721-18765 Disease denotes secondary hemophagocytic lymphohistiocytosis MESH:D051359
568 15875-15880 Gene denotes FIZZ1 Gene:84666
569 16631-16636 Gene denotes hACE2 Gene:59272
570 17195-17199 Gene denotes CCL2 Gene:6347
571 17204-17208 Gene denotes IL-8 Gene:3576
572 17346-17348 Gene denotes to Gene:6999
573 17311-17313 Gene denotes to Gene:6999
574 17268-17270 Gene denotes to Gene:6999
575 17067-17069 Gene denotes to Gene:6999
576 16454-16456 Gene denotes to Gene:6999
577 15661-15663 Gene denotes to Gene:6999
578 15546-15548 Gene denotes to Gene:6999
579 15527-15535 Species denotes patients Tax:9606
580 15604-15612 Species denotes SARS-CoV Tax:694009
581 15619-15627 Species denotes MERS-CoV Tax:1335626
582 15737-15742 Species denotes mouse Tax:10090
583 16037-16043 Species denotes murine Tax:10090
584 16044-16052 Species denotes SARS-CoV Tax:694009
585 16371-16381 Species denotes SARS-CoV-2 Tax:2697049
586 16472-16478 Species denotes murine Tax:10090
587 16479-16482 Species denotes CoV Tax:11118
588 16556-16566 Species denotes SARS-CoV-2 Tax:2697049
589 16637-16641 Species denotes mice Tax:10090
590 16847-16854 Species denotes patient Tax:9606
591 16896-16901 Species denotes human Tax:9606
592 16928-16935 Species denotes patient Tax:9606
593 16944-16952 Species denotes SARS-CoV Tax:694009
594 15518-15526 Disease denotes COVID-19 MESH:C000657245
595 15576-15600 Disease denotes myeloid cell dysfunction MESH:D023981
596 15678-15686 Disease denotes COVID-19 MESH:C000657245
597 15713-15733 Disease denotes SARS-CoV-1 infection MESH:C000657245
598 15926-15942 Disease denotes hypersensitivity MESH:D004342
599 15978-15986 Disease denotes fibrosis MESH:D005355
600 16694-16703 Disease denotes pneumonia MESH:D011014
601 17051-17062 Disease denotes lung injury MESH:D055370
604 18795-18797 Gene denotes to Gene:6999
605 18809-18821 Disease denotes Inflammation MESH:D007249
634 19226-19230 Gene denotes ACE2 Gene:59272
635 19317-19322 Gene denotes CD169 Gene:6614
636 19367-19371 Gene denotes IL-6 Gene:3569
637 19461-19465 Gene denotes IL-6 Gene:3569
638 19598-19602 Gene denotes IL-6 Gene:3569
639 19648-19652 Gene denotes IL-2 Gene:3558
640 19654-19658 Gene denotes IL-7 Gene:3574
641 19660-19665 Gene denotes IFN-ɣ Gene:3458
642 19671-19677 Gene denotes GM-CSF Gene:1437
643 20143-20148 Gene denotes NLRP3 Gene:114548
644 20405-20412 Gene denotes RIPK1/3 Gene:8737
645 19531-19533 Gene denotes to Gene:6999
646 19054-19056 Gene denotes to Gene:6999
647 19057-19065 Species denotes MERS-CoV Tax:1335626
648 19186-19196 Species denotes SARS-CoV-2 Tax:2697049
649 19235-19245 Species denotes SARS-CoV-2 Tax:2697049
650 19348-19356 Species denotes patients Tax:9606
651 19505-19512 Species denotes patient Tax:9606
652 19070-19090 Disease denotes SARS-CoV-1 infection MESH:C000657245
653 19174-19182 Disease denotes infected MESH:D007239
654 19339-19347 Disease denotes COVID-19 MESH:C000657245
655 19496-19504 Disease denotes COVID-19 MESH:C000657245
656 19700-19734 Disease denotes hemophagocytic lymphohistiocytosis MESH:D051359
657 19751-19767 Disease denotes viral infections MESH:D001102
658 20067-20087 Disease denotes SARS-CoV-1 infection MESH:C000657245
659 20187-20208 Disease denotes macrophage pyroptosis MESH:D055501
660 20332-20340 Disease denotes COVID-19 MESH:C000657245
661 20547-20555 Disease denotes COVID-19 MESH:C000657245
666 20844-20846 Gene denotes to Gene:6999
667 20654-20656 Gene denotes to Gene:6999
668 20742-20752 Species denotes SARS-CoV-2 Tax:2697049
669 20887-20894 Disease denotes NETosis
674 21167-21169 Gene denotes to Gene:6999
675 21114-21118 Species denotes CoVs Tax:11118
676 21123-21143 Disease denotes SARS-CoV-2 infection MESH:C000657245
677 21222-21230 Disease denotes COVID-19 MESH:C000657245
680 21716-21730 Gene denotes CD56brightCD16 Gene:4684
681 21813-21825 Disease denotes cytotoxicity MESH:D064420
683 21892-21900 Disease denotes COVID-19 MESH:C000657245
702 22413-22418 Gene denotes CXCR3 Gene:2833
703 22524-22529 Gene denotes CXCR3 Gene:2833
704 22539-22547 Gene denotes CXCL9-11 Gene:4283
705 22628-22633 Gene denotes CXCR3 Gene:2833
706 22752-22757 Gene denotes CXCR3 Gene:2833
707 22829-22831 Gene denotes to Gene:6999
708 22434-22436 Gene denotes to Gene:6999
709 22005-22013 Species denotes patients Tax:9606
710 22263-22271 Species denotes patients Tax:9606
711 22586-22591 Species denotes human Tax:9606
712 22699-22707 Species denotes patients Tax:9606
713 22854-22862 Species denotes patients Tax:9606
714 22471-22480 Species denotes influenza Tax:11520
715 21996-22004 Disease denotes COVID-19 MESH:C000657245
716 22481-22490 Disease denotes infection MESH:D007239
717 22566-22585 Disease denotes SARS-CoV-2-infected MESH:C000657245
718 22690-22698 Disease denotes COVID-19 MESH:C000657245
719 22845-22853 Disease denotes COVID-19 MESH:C000657245
745 23225-23230 Gene denotes NKp46 Gene:9437
746 23380-23391 Gene denotes NK receptor Gene:3804
747 23556-23560 Gene denotes IgG3 Gene:3502
748 24193-24194 Gene denotes S Gene:43740568
749 24116-24118 Gene denotes to Gene:6999
750 23776-23778 Gene denotes to Gene:6999
751 23725-23727 Gene denotes to Gene:6999
752 23438-23440 Gene denotes to Gene:6999
753 23037-23039 Gene denotes to Gene:6999
754 24182-24192 Species denotes SARS-CoV-2 Tax:2697049
755 24230-24245 Species denotes Chinese hamster Tax:10029
756 23997-24006 Species denotes influenza Tax:11520
757 24138-24146 Species denotes SARS-CoV Tax:694009
758 22999-23011 Disease denotes cytotoxicity MESH:D064420
759 23060-23074 Disease denotes virus-infected MESH:D001102
760 23403-23422 Disease denotes SARS-CoV-2-infected MESH:C000657245
761 23507-23515 Disease denotes COVID-19 MESH:C000657245
762 23579-23599 Disease denotes SARS-CoV-2 infection MESH:C000657245
763 23758-23766 Disease denotes infected MESH:D007239
764 23914-23922 Disease denotes infected MESH:D007239
765 23964-23976 Disease denotes cytotoxicity MESH:D064420
766 24007-24016 Disease denotes infection MESH:D007239
767 24389-24398 Disease denotes infection MESH:D007239
768 24445-24449 Disease denotes ARDS MESH:D012128
769 24253-24256 CellLine denotes CHO CVCL:0213
771 24486-24506 Disease denotes SARS-CoV-2 Infection MESH:C000657245
794 24608-24614 Gene denotes CD107a Gene:3916
795 24616-24621 Gene denotes Ksp37 Gene:643236
796 24623-24633 Gene denotes granzyme B Gene:3002
797 24639-24649 Gene denotes granulysin Gene:10578
798 24737-24742 Gene denotes IFN-ɣ Gene:3458
799 24748-24753 Gene denotes TNF-α Gene:7124
800 25007-25011 Gene denotes ACE2 Gene:59272
801 25172-25175 Gene denotes KIR Gene:3805
802 24558-24566 Species denotes patients Tax:9606
803 24868-24883 Species denotes influenza virus Tax:11308
804 24995-25005 Species denotes SARS-CoV-2 Tax:2697049
805 25067-25077 Species denotes SARS-CoV-2 Tax:2697049
806 25139-25144 Species denotes human Tax:9606
807 25727-25737 Species denotes SARS-CoV-2 Tax:2697049
808 26015-26023 Species denotes patients Tax:9606
809 25258-25263 Species denotes human Tax:9606
810 24549-24557 Disease denotes COVID-19 MESH:C000657245
811 24665-24686 Disease denotes impaired cytotoxicity MESH:D064420
812 25055-25063 Disease denotes infected MESH:D007239
813 25222-25234 Disease denotes cytotoxicity MESH:D064420
814 25747-25762 Disease denotes CoV-1 infection MESH:D018352
815 25995-26014 Disease denotes SARS-CoV-2-infected MESH:C000657245
852 26047-26052 Gene denotes NKG2A Gene:3821
853 26140-26145 Gene denotes NKG2A Gene:3821
854 26202-26207 Gene denotes HLA-E Gene:3133
855 26406-26410 Gene denotes LAG3 Gene:3902
856 26415-26419 Gene denotes TIM3 Gene:84868
857 26669-26673 Gene denotes IL-6 Gene:3569
858 26820-26824 Gene denotes IL-6 Gene:3569
859 26918-26928 Gene denotes granzyme B Gene:3002
860 27025-27030 Gene denotes IL-6R Gene:3570
861 27065-27070 Gene denotes TNF-α Gene:7124
862 27257-27262 Gene denotes TNF-α Gene:7124
863 27323-27328 Gene denotes TNF-α Gene:7124
864 27432-27437 Gene denotes NKp46 Gene:9437
865 27482-27487 Gene denotes TNF-α Gene:7124
866 27491-27495 Gene denotes IL-6 Gene:3569
867 27710-27714 Gene denotes IL-6 Gene:3569
868 27719-27722 Gene denotes TNF Gene:7124
869 27352-27354 Gene denotes to Gene:6999
870 27338-27340 Gene denotes to Gene:6999
871 27274-27276 Gene denotes to Gene:6999
872 26583-26585 Gene denotes to Gene:6999
873 26082-26085 Gene denotes CD8 Gene:925
874 26108-26116 Species denotes patients Tax:9606
875 26467-26475 Species denotes patients Tax:9606
876 26623-26631 Species denotes patients Tax:9606
877 27117-27125 Species denotes patients Tax:9606
878 27784-27792 Species denotes patients Tax:9606
879 27012-27023 Chemical denotes tocilizumab MESH:C502936
880 26099-26107 Disease denotes COVID-19 MESH:C000657245
881 26160-26172 Disease denotes cytotoxicity MESH:D064420
882 26325-26340 Disease denotes HIV-1 infection MESH:D015658
883 26458-26466 Disease denotes COVID-19 MESH:C000657245
884 26614-26622 Disease denotes COVID-19 MESH:C000657245
885 27108-27116 Disease denotes COVID-19 MESH:C000657245
886 27658-27677 Disease denotes SARS-CoV-2-infected MESH:C000657245
887 27775-27783 Disease denotes COVID-19 MESH:C000657245
889 27835-27855 Disease denotes SARS-CoV-2 Infection MESH:C000657245
905 28142-28154 Gene denotes amphiregulin Gene:11839
906 28278-28283 Gene denotes IL-13 Gene:3596
907 28602-28607 Gene denotes IL-13 Gene:3596
908 28332-28334 Gene denotes to Gene:6999
909 28298-28300 Gene denotes to Gene:6999
910 27868-27870 Gene denotes to Gene:6999
911 28129-28133 Species denotes mice Tax:10090
912 28718-28726 Species denotes patients Tax:9606
913 28106-28115 Species denotes influenza Tax:11520
914 28348-28357 Species denotes influenza Tax:11520
915 28205-28211 Chemical denotes oxygen MESH:D010100
916 27924-27944 Disease denotes SARS-CoV-2 infection MESH:C000657245
917 28116-28125 Disease denotes infection MESH:D007239
918 28709-28717 Disease denotes COVID-19 MESH:C000657245
919 28755-28775 Disease denotes SARS-CoV-2 infection MESH:C000657245
932 28879-28882 Gene denotes CD4 Gene:920
933 28995-28998 Gene denotes CD8 Gene:925
934 29503-29505 Gene denotes to Gene:6999
935 29425-29427 Gene denotes to Gene:6999
936 29290-29292 Gene denotes to Gene:6999
937 29125-29127 Gene denotes To Gene:6999
938 29027-29029 Gene denotes to Gene:6999
939 28861-28877 Disease denotes viral infections MESH:D001102
940 29012-29020 Disease denotes infected MESH:D007239
941 29178-29198 Disease denotes SARS-CoV-2 infection MESH:C000657245
942 29351-29359 Disease denotes COVID-19 MESH:C000657245
943 29376-29384 Disease denotes memory T MESH:D008569
946 29536-29539 Gene denotes CD4 Gene:920
947 29544-29547 Gene denotes CD8 Gene:925
950 30743-30745 Gene denotes to Gene:6999
951 30746-30756 Species denotes SARS-CoV-2 Tax:2697049
963 30998-31001 Gene denotes CD4 Gene:920
964 31006-31009 Gene denotes CD8 Gene:925
965 31297-31300 Gene denotes CD4 Gene:920
966 31580-31582 Gene denotes to Gene:6999
967 31408-31410 Gene denotes to Gene:6999
968 31358-31360 Gene denotes to Gene:6999
969 31528-31535 Species denotes patient Tax:9606
970 30895-30907 Disease denotes inflammation MESH:D007249
971 30934-30942 Disease denotes COVID-19 MESH:C000657245
972 31085-31093 Disease denotes COVID-19 MESH:C000657245
973 31215-31227 Disease denotes cytotoxicity MESH:D064420
982 31716-31722 Gene denotes GM-CSF Gene:1437
983 31724-31772 Gene denotes granulocyte-macrophage colony-stimulating factor Gene:1437
984 31774-31778 Gene denotes GzmA Gene:3001
985 31782-31792 Gene denotes granzyme A Gene:3001
986 31793-31803 Gene denotes granzyme B Gene:3002
987 31805-31809 Gene denotes Prf1 Gene:5551
988 31688-31691 Gene denotes TNF Gene:7124
989 31693-31707 Disease denotes tumor necrosis MESH:D009336
1009 29765-29768 Gene denotes CD4 Gene:920
1010 29980-29983 Gene denotes CD8 Gene:925
1011 29773-29776 Gene denotes CD8 Gene:925
1012 30644-30646 Gene denotes to Gene:6999
1013 30495-30497 Gene denotes to Gene:6999
1014 30013-30015 Gene denotes to Gene:6999
1015 29590-29592 Gene denotes to Gene:6999
1016 29995-30003 Species denotes patients Tax:9606
1017 30300-30308 Species denotes Patients Tax:9606
1018 30647-30655 Species denotes MERS-CoV Tax:1335626
1019 29620-29640 Disease denotes SARS-CoV-1 infection MESH:C000657245
1020 29712-29723 Disease denotes lymphopenia MESH:D008231
1021 29808-29816 Disease denotes COVID-19 MESH:C000657245
1022 29950-29961 Disease denotes lymphopenia MESH:D008231
1023 30072-30080 Disease denotes COVID-19 MESH:C000657245
1024 30113-30122 Disease denotes mortality MESH:D003643
1025 30505-30513 Disease denotes COVID-19 MESH:C000657245
1026 30558-30574 Disease denotes viral infections MESH:D001102
1027 30604-30619 Disease denotes viral infection MESH:D001102
1061 32012-32016 Gene denotes IL-6 Gene:3569
1062 32018-32023 Gene denotes IL-10 Gene:3586
1063 32029-32034 Gene denotes TNF-α Gene:7124
1064 32341-32346 Gene denotes TNF-α Gene:7124
1065 32713-32717 Gene denotes IL-6 Gene:3569
1066 32733-32737 Gene denotes FasL Gene:356
1067 33155-33158 Gene denotes CD8 Gene:925
1068 33576-33578 Gene denotes to Gene:6999
1069 33281-33283 Gene denotes to Gene:6999
1070 32963-32965 Gene denotes to Gene:6999
1071 32855-32857 Gene denotes to Gene:6999
1072 32609-32611 Gene denotes to Gene:6999
1073 32446-32448 Gene denotes to Gene:6999
1074 32114-32116 Gene denotes to Gene:6999
1075 31988-31990 Gene denotes to Gene:6999
1076 31858-31860 Gene denotes to Gene:6999
1077 32094-32102 Species denotes patients Tax:9606
1078 32586-32594 Species denotes patients Tax:9606
1079 33122-33130 Species denotes patients Tax:9606
1080 33259-33266 Species denotes patient Tax:9606
1081 33471-33479 Species denotes patients Tax:9606
1082 33666-33674 Species denotes patients Tax:9606
1083 32833-32844 Chemical denotes tocilizumab MESH:C502936
1084 31970-31981 Disease denotes lymphopenia MESH:D008231
1085 32612-32620 Disease denotes COVID-19 MESH:C000657245
1086 32658-32663 Disease denotes death MESH:D003643
1087 32975-32984 Disease denotes infection MESH:D007239
1088 33113-33121 Disease denotes COVID-19 MESH:C000657245
1089 33284-33288 Disease denotes ARDS MESH:D012128
1090 33304-33319 Disease denotes CoV-2 infection MESH:C000657245
1091 33462-33470 Disease denotes COVID-19 MESH:C000657245
1092 33642-33653 Disease denotes lymphopenia MESH:D008231
1093 33657-33665 Disease denotes COVID-19 MESH:C000657245
1171 33964-33968 Gene denotes ORF3 Gene:136991
1172 33980-33983 Gene denotes CD4 Gene:920
1173 34123-34126 Gene denotes CD8 Gene:925
1174 34159-34162 Gene denotes CD4 Gene:920
1175 34546-34550 Gene denotes IL-4 Gene:3565
1176 34552-34556 Gene denotes IL-5 Gene:3567
1177 34558-34563 Gene denotes IL-10 Gene:3586
1178 34624-34627 Gene denotes CD4 Gene:920
1179 34946-34951 Gene denotes IFN-γ Gene:3458
1180 35414-35417 Gene denotes CD4 Gene:920
1181 35422-35425 Gene denotes CD8 Gene:925
1182 35561-35567 Gene denotes CD45RA Gene:5788
1183 35572-35576 Gene denotes CCR7 Gene:1236
1184 35645-35648 Gene denotes CD4 Gene:920
1185 35673-35676 Gene denotes CD8 Gene:925
1186 36059-36062 Gene denotes CD4 Gene:920
1187 36067-36070 Gene denotes CD8 Gene:925
1188 36290-36295 Gene denotes CD137 Gene:3604
1189 36333-36338 Gene denotes CD137 Gene:3604
1190 36342-36345 Gene denotes CD4 Gene:920
1191 36370-36375 Gene denotes CD154 Gene:959
1192 36542-36547 Gene denotes IFN-γ Gene:3458
1193 36549-36554 Gene denotes TNF-α Gene:7124
1194 36560-36564 Gene denotes IL-2 Gene:3558
1195 36598-36602 Gene denotes IL-5 Gene:3567
1196 36604-36609 Gene denotes IL-13 Gene:3596
1197 36611-36615 Gene denotes IL-9 Gene:3578
1198 36617-36622 Gene denotes IL-10 Gene:3586
1199 36628-36633 Gene denotes IL-22 Gene:50616
1200 36792-36797 Gene denotes CD154 Gene:959
1201 36802-36807 Gene denotes CD137 Gene:3604
1202 36849-36852 Gene denotes CD4 Gene:920
1203 37092-37095 Gene denotes CD4 Gene:920
1204 37177-37180 Gene denotes CD4 Gene:920
1205 37358-37361 Gene denotes CD4 Gene:920
1206 37081-37082 Gene denotes S Gene:43740568
1207 36473-36474 Gene denotes S Gene:43740568
1208 36083-36084 Gene denotes S Gene:43740568
1209 35870-35871 Gene denotes S Gene:43740568
1210 34679-34681 Gene denotes to Gene:6999
1211 34651-34653 Gene denotes to Gene:6999
1212 34022-34024 Gene denotes to Gene:6999
1213 34411-34414 Gene denotes CD4 Gene:920
1214 33745-33753 Species denotes SARS-CoV Tax:694009
1215 34061-34069 Species denotes SARS-CoV Tax:694009
1216 34364-34372 Species denotes patients Tax:9606
1217 34825-34833 Species denotes patients Tax:9606
1218 35046-35054 Species denotes SARS-CoV Tax:694009
1219 35057-35065 Species denotes patients Tax:9606
1220 35257-35265 Species denotes patients Tax:9606
1221 35455-35463 Species denotes patients Tax:9606
1222 35825-35835 Species denotes SARS-Cov-2 Tax:2697049
1223 36699-36707 Species denotes patients Tax:9606
1224 37114-37124 Species denotes SARS-CoV-2 Tax:2697049
1225 37316-37321 Species denotes human Tax:9606
1226 37322-37326 Species denotes CoVs Tax:11118
1227 37404-37412 Species denotes children Tax:9606
1228 37425-37433 Species denotes patients Tax:9606
1229 37532-37542 Species denotes SARS-CoV-2 Tax:2697049
1230 37602-37605 Species denotes CoV Tax:11118
1231 37744-37747 Species denotes CoV Tax:11118
1232 37779-37789 Species denotes SARS-CoV-2 Tax:2697049
1233 37662-37670 Species denotes SARS-CoV Tax:694009
1234 37615-37618 Gene denotes CD4 Gene:920
1235 36672-36675 Gene denotes CD4 Gene:920
1236 33838-33858 Disease denotes SARS-CoV-2 infection MESH:C000657245
1237 34127-34135 Disease denotes memory T MESH:D008569
1238 34163-34171 Disease denotes memory T MESH:D008569
1239 34797-34817 Disease denotes SARS-CoV-2 infection MESH:C000657245
1240 34855-34863 Disease denotes COVID-19 MESH:C000657245
1241 35248-35256 Disease denotes COVID-19 MESH:C000657245
1242 35290-35294 Disease denotes ARDS MESH:D012128
1243 35726-35728 Disease denotes RA MESH:D001172
1244 36739-36747 Disease denotes COVID-19 MESH:C000657245
1245 37362-37370 Disease denotes memory T MESH:D008569
1246 37477-37487 Disease denotes infections MESH:D007239
1247 37720-37730 Disease denotes infections MESH:D007239
1253 37903-37913 Species denotes SARS-CoV-2 Tax:2697049
1254 38112-38120 Species denotes patients Tax:9606
1255 38217-38227 Species denotes SARS-CoV-2 Tax:2697049
1256 38327-38335 Species denotes patients Tax:9606
1257 38145-38153 Disease denotes COVID-19 MESH:C000657245
1260 38433-38435 Gene denotes to Gene:6999
1261 38436-38462 Disease denotes COVID-19 Hyperinflammation MESH:C000657245
1288 38797-38803 Gene denotes GM-CSF Gene:1437
1289 38805-38808 Gene denotes CD4 Gene:920
1290 38847-38851 Gene denotes IL-6 Gene:3569
1291 38856-38861 Gene denotes IFN-γ Gene:3458
1292 38945-38951 Gene denotes GM-CSF Gene:1437
1293 38953-38956 Gene denotes CD4 Gene:920
1294 39126-39132 Gene denotes GM-CSF Gene:1437
1295 39134-39137 Gene denotes CD4 Gene:920
1296 38629-38631 Gene denotes to Gene:6999
1297 38661-38669 Species denotes patients Tax:9606
1298 38905-38913 Species denotes patients Tax:9606
1299 39429-39434 Species denotes mouse Tax:10090
1300 39758-39766 Species denotes patients Tax:9606
1301 39653-39662 Species denotes influenza Tax:11520
1302 38652-38660 Disease denotes COVID-19 MESH:C000657245
1303 38881-38895 Disease denotes critically ill MESH:D016638
1304 38896-38904 Disease denotes COVID-19 MESH:C000657245
1305 39013-39032 Disease denotes autoimmune diseases MESH:D001327
1306 39042-39060 Disease denotes multiple sclerosis MESH:D009103
1307 39064-39093 Disease denotes juvenile rheumatoid arthritis MESH:D001171
1308 39196-39202 Disease denotes sepsis MESH:D018805
1309 39304-39312 Disease denotes COVID-19 MESH:C000657245
1310 39408-39425 Disease denotes ARDS inflammation MESH:D012128
1311 39517-39525 Disease denotes COVID-19 MESH:C000657245
1312 39663-39672 Disease denotes pneumonia MESH:D011014
1313 39749-39757 Disease denotes COVID-19 MESH:C000657245
1315 39851-39859 Disease denotes COVID-19 MESH:C000657245
1328 40370-40373 Gene denotes CD8 Gene:925
1329 40413-40416 Gene denotes CD4 Gene:920
1330 40521-40524 Gene denotes CD8 Gene:925
1331 40530-40533 Gene denotes CD4 Gene:920
1332 40847-40849 Gene denotes to Gene:6999
1333 40706-40708 Gene denotes to Gene:6999
1334 40387-40389 Gene denotes to Gene:6999
1335 40558-40566 Species denotes SARS-CoV Tax:694009
1336 40632-40640 Species denotes patients Tax:9606
1337 39964-39972 Disease denotes COVID-19 MESH:C000657245
1338 40343-40351 Disease denotes COVID-19 MESH:C000657245
1339 40623-40631 Disease denotes COVID-19 MESH:C000657245
1390 41100-41105 Gene denotes OX-40 Gene:7293
1391 41110-41115 Gene denotes CD137 Gene:3604
1395 41236-41239 Gene denotes CD8 Gene:925
1396 41306-41310 Gene denotes TIM3 Gene:84868
1397 41312-41315 Gene denotes CD8 Gene:925
1398 41443-41446 Gene denotes CD8 Gene:925
1399 41631-41634 Gene denotes CD4 Gene:920
1400 41639-41642 Gene denotes CD8 Gene:925
1401 41792-41797 Gene denotes IFN-γ Gene:3458
1402 41802-41807 Gene denotes TNF-α Gene:7124
1403 41996-41999 Gene denotes CD8 Gene:925
1404 42080-42086 Gene denotes CD107a Gene:3916
1405 42105-42115 Gene denotes granzyme B Gene:3002
1406 42117-42121 Gene denotes GzmB Gene:3002
1407 42204-42208 Gene denotes GzmB Gene:3002
1408 42520-42523 Gene denotes CD4 Gene:920
1409 42547-42552 Gene denotes IFN-γ Gene:3458
1410 42554-42559 Gene denotes TNF-α Gene:7124
1411 42565-42569 Gene denotes IL-2 Gene:3558
1412 42574-42577 Gene denotes CD8 Gene:925
1413 42601-42606 Gene denotes IFN-γ Gene:3458
1414 42608-42613 Gene denotes TNF-α Gene:7124
1415 42619-42625 Gene denotes CD107a Gene:3916
1416 42921-42924 Gene denotes CD8 Gene:925
1417 43010-43014 Gene denotes GZMA Gene:3001
1418 43016-43020 Gene denotes GZMB Gene:3002
1419 43026-43030 Gene denotes GZMK Gene:3003
1420 43055-43060 Gene denotes KLRC1 Gene:3821
1421 43065-43069 Gene denotes XCL1 Gene:6375
1422 42240-42243 Gene denotes CD8 Gene:925
1423 41613-41615 Gene denotes to Gene:6999
1424 41550-41552 Gene denotes to Gene:6999
1425 41486-41488 Gene denotes to Gene:6999
1426 41427-41429 Gene denotes to Gene:6999
1427 41455-41458 Gene denotes CD4 Gene:920
1428 41331-41339 Species denotes patients Tax:9606
1429 41669-41677 Species denotes patients Tax:9606
1430 42269-42277 Species denotes patients Tax:9606
1431 42400-42408 Species denotes patients Tax:9606
1432 42969-42977 Species denotes patients Tax:9606
1433 41848-41873 Chemical denotes phorbol myristate acetate MESH:D013755
1434 41875-41878 Chemical denotes PMA MESH:D013755
1435 41884-41893 Chemical denotes ionomycin MESH:D015759
1436 41654-41668 Disease denotes critically ill MESH:D016638
1437 42018-42026 Disease denotes COVID-19 MESH:C000657245
1438 42430-42450 Disease denotes SARS-CoV-1 infection MESH:C000657245
1439 42960-42968 Disease denotes COVID-19 MESH:C000657245
1451 43295-43300 Gene denotes TIM-3 Gene:84868
1452 43448-43451 Gene denotes CD4 Gene:920
1453 43581-43585 Gene denotes GzmB Gene:3002
1454 43574-43579 Gene denotes Gzm A Gene:3001
1455 43797-43799 Gene denotes to Gene:6999
1456 43407-43409 Gene denotes to Gene:6999
1457 43162-43164 Gene denotes to Gene:6999
1458 43387-43395 Species denotes patients Tax:9606
1459 43148-43156 Disease denotes COVID-19 MESH:C000657245
1460 43350-43362 Disease denotes cytotoxicity MESH:D064420
1461 43750-43770 Disease denotes SARS-CoV-2 infection MESH:C000657245
1466 44354-44356 Gene denotes to Gene:6999
1467 44108-44118 Species denotes SARS-CoV-2 Tax:2697049
1468 44357-44367 Species denotes SARS-CoV-2 Tax:2697049
1469 44305-44314 Disease denotes infection MESH:D007239
1476 45951-45953 Gene denotes to Gene:6999
1477 45877-45885 Species denotes patients Tax:9606
1478 45979-45987 Species denotes SARS-CoV Tax:694009
1479 46109-46119 Species denotes SARS-CoV-2 Tax:2697049
1480 45862-45876 Disease denotes critically ill MESH:D016638
1481 46153-46162 Disease denotes infection MESH:D007239
1506 45156-45160 Gene denotes ACE2 Gene:59272
1507 44838-44839 Gene denotes N Gene:43740575
1508 45000-45001 Gene denotes S Gene:43740568
1509 44865-44866 Gene denotes S Gene:43740568
1510 45461-45463 Gene denotes to Gene:6999
1511 45363-45365 Gene denotes to Gene:6999
1512 45328-45330 Gene denotes to Gene:6999
1513 44433-44435 Gene denotes to Gene:6999
1514 44518-44526 Species denotes patients Tax:9606
1515 44818-44828 Species denotes SARS-CoV-2 Tax:2697049
1516 45240-45248 Species denotes patients Tax:9606
1517 45331-45339 Species denotes SARS-CoV Tax:694009
1518 45366-45374 Species denotes MERS-CoV Tax:1335626
1519 45422-45430 Species denotes patients Tax:9606
1520 45477-45485 Species denotes SARS-CoV Tax:694009
1521 45491-45499 Species denotes MERS-CoV Tax:1335626
1522 45535-45543 Species denotes patients Tax:9606
1523 45563-45571 Species denotes SARS-CoV Tax:694009
1524 45577-45585 Species denotes MERS-CoV Tax:1335626
1525 45207-45211 Chemical denotes nAbs
1526 44436-44456 Disease denotes SARS-CoV-1 infection MESH:C000657245
1527 44509-44517 Disease denotes COVID-19 MESH:C000657245
1528 45413-45421 Disease denotes COVID-19 MESH:C000657245
1529 45526-45534 Disease denotes COVID-19 MESH:C000657245
1538 46615-46617 Gene denotes to Gene:6999
1539 46598-46600 Gene denotes to Gene:6999
1540 46687-46697 Species denotes SARS-CoV-2 Tax:2697049
1541 46792-46800 Species denotes SARS-CoV Tax:694009
1542 46806-46814 Species denotes MERS-CoV Tax:1335626
1543 46374-46384 Species denotes SARS-CoV-2 Tax:2697049
1544 46249-46257 Disease denotes COVID-19 MESH:C000657245
1545 46645-46661 Disease denotes acute infections MESH:D007239
1554 47477-47479 Gene denotes to Gene:6999
1555 47310-47312 Gene denotes to Gene:6999
1556 47275-47277 Gene denotes to Gene:6999
1557 47119-47121 Gene denotes to Gene:6999
1558 47071-47073 Gene denotes to Gene:6999
1559 47044-47046 Gene denotes to Gene:6999
1560 47194-47203 Disease denotes infection MESH:D007239
1561 47388-47397 Disease denotes infection MESH:D007239
1579 48532-48534 Gene denotes to Gene:6999
1580 48118-48120 Gene denotes to Gene:6999
1581 48018-48020 Gene denotes to Gene:6999
1582 47828-47830 Gene denotes to Gene:6999
1583 47723-47725 Gene denotes to Gene:6999
1584 47726-47736 Species denotes SARS-CoV-2 Tax:2697049
1585 47904-47912 Species denotes patients Tax:9606
1586 48167-48174 Species denotes patient Tax:9606
1587 48589-48597 Species denotes patients Tax:9606
1588 48729-48744 Species denotes rhesus macaques Tax:9544
1589 47895-47903 Disease denotes COVID-19 MESH:C000657245
1590 48389-48403 Disease denotes critically ill MESH:D016638
1591 48580-48588 Disease denotes COVID-19 MESH:C000657245
1592 48667-48675 Disease denotes COVID-19 MESH:C000657245
1593 48676-48685 Disease denotes infection MESH:D007239
1594 48705-48725 Disease denotes SARS-CoV-2 infection MESH:C000657245
1595 48799-48808 Disease denotes infection MESH:D007239
1613 49490-49492 Gene denotes to Gene:6999
1614 49408-49410 Gene denotes to Gene:6999
1615 48933-48935 Gene denotes to Gene:6999
1616 48878-48880 Gene denotes to Gene:6999
1617 49038-49043 Species denotes human Tax:9606
1618 49044-49048 Species denotes CoVs Tax:11118
1619 49069-49074 Species denotes human Tax:9606
1620 49075-49078 Species denotes CoV Tax:11118
1621 49411-49419 Species denotes SARS-CoV Tax:694009
1622 49822-49830 Species denotes MERS-CoV Tax:1335626
1623 49102-49106 Chemical denotes nAbs
1624 49176-49185 Disease denotes infection MESH:D007239
1625 49319-49334 Disease denotes CoV-1 infection MESH:D018352
1626 49450-49459 Disease denotes infection MESH:D007239
1627 49586-49600 Disease denotes CoV-1-infected MESH:D018352
1628 49777-49786 Disease denotes infection MESH:D007239
1629 49905-49914 Disease denotes infection MESH:D007239
1643 49973-49978 Gene denotes spike Gene:43740568
1644 50723-50728 Gene denotes IFN-γ Gene:3458
1645 50647-50649 Gene denotes to Gene:6999
1646 50408-50410 Gene denotes to Gene:6999
1647 50014-50016 Gene denotes to Gene:6999
1648 49950-49952 Gene denotes to Gene:6999
1649 49953-49963 Species denotes SARS-CoV-2 Tax:2697049
1650 50239-50247 Species denotes SARS-CoV Tax:694009
1651 50542-50550 Species denotes SARS-CoV Tax:694009
1652 50316-50325 Disease denotes infection MESH:D007239
1653 50426-50435 Disease denotes infection MESH:D007239
1654 50596-50605 Disease denotes infection MESH:D007239
1655 50654-50662 Disease denotes memory T MESH:D008569
1664 51084-51086 Gene denotes to Gene:6999
1665 50989-50991 Gene denotes to Gene:6999
1666 50779-50783 Species denotes CoVs Tax:11118
1667 50784-50792 Species denotes SARS-CoV Tax:694009
1668 50799-50807 Species denotes MERS-CoV Tax:1335626
1669 50898-50902 Species denotes CoVs Tax:11118
1670 50992-51002 Species denotes SARS-CoV-2 Tax:2697049
1671 51036-51045 Disease denotes infection MESH:D007239
1676 51798-51800 Gene denotes to Gene:6999
1677 51287-51289 Gene denotes to Gene:6999
1678 51290-51300 Species denotes SARS-CoV-2 Tax:2697049
1679 51410-51418 Species denotes patients Tax:9606
1702 52391-52393 Gene denotes to Gene:6999
1703 52121-52123 Gene denotes to Gene:6999
1704 52089-52091 Gene denotes to Gene:6999
1705 52053-52055 Gene denotes to Gene:6999
1706 51988-51990 Gene denotes to Gene:6999
1707 51931-51933 Gene denotes to Gene:6999
1708 51873-51881 Species denotes SARS-CoV Tax:694009
1709 51970-51978 Species denotes patients Tax:9606
1710 51991-51999 Species denotes patients Tax:9606
1711 52487-52502 Species denotes rhesus macaques Tax:9544
1712 52702-52710 Species denotes SARS-CoV Tax:694009
1713 52713-52721 Species denotes patients Tax:9606
1714 52748-52756 Species denotes SARS-CoV Tax:694009
1715 52762-52767 Species denotes human Tax:9606
1716 52891-52898 Species denotes patient Tax:9606
1717 52904-52912 Species denotes MERS-CoV Tax:1335626
1718 53008-53012 Species denotes rats Tax:10116
1719 53029-53039 Species denotes SARS-CoV-2 Tax:2697049
1720 53122-53132 Species denotes SARS-CoV-2 Tax:2697049
1721 52467-52486 Disease denotes SARS-CoV-1-infected MESH:C000657245
1722 52547-52564 Disease denotes acute lung injury MESH:D055371
1723 52735-52744 Disease denotes infection MESH:D007239
1735 53867-53869 Gene denotes to Gene:6999
1736 53781-53783 Gene denotes to Gene:6999
1737 53757-53759 Gene denotes to Gene:6999
1738 53381-53383 Gene denotes to Gene:6999
1739 53269-53271 Gene denotes to Gene:6999
1740 53247-53257 Species denotes SARS-CoV-2 Tax:2697049
1741 53511-53514 Species denotes CoV Tax:11118
1742 53677-53685 Species denotes patients Tax:9606
1743 53310-53318 Disease denotes COVID-19 MESH:C000657245
1744 53668-53676 Disease denotes COVID-19 MESH:C000657245
1745 53820-53840 Disease denotes SARS-CoV-2 infection MESH:C000657245
1747 54115-54123 Disease denotes COVID-19 MESH:C000657245
1750 54250-54258 Disease denotes COVID-19 MESH:C000657245
1751 54459-54474 Disease denotes CoV-2 infection MESH:C000657245
1764 54809-54824 Gene denotes ABO blood group Gene:28
1765 55056-55058 Gene denotes to Gene:6999
1766 54983-54985 Gene denotes to Gene:6999
1767 54877-54879 Gene denotes to Gene:6999
1768 54718-54720 Gene denotes to Gene:6999
1769 54868-54876 Species denotes patients Tax:9606
1770 55059-55064 Species denotes non-A Tax:12440
1771 55319-55326 Species denotes SARS-Co Tax:694009
1772 54721-54729 Disease denotes COVID-19 MESH:C000657245
1773 54859-54867 Disease denotes COVID-19 MESH:C000657245
1774 55033-55041 Disease denotes COVID-19 MESH:C000657245
1775 55121-55130 Disease denotes infection MESH:D007239
1791 56303-56307 Gene denotes ACE2 Gene:59272
1792 56334-56341 Gene denotes TMPRSS2 Gene:7113
1793 56343-56348 Gene denotes spike Gene:43740568
1794 56553-56557 Gene denotes ACE2 Gene:59272
1795 56592-56596 Gene denotes ACE2 Gene:59272
1796 56747-56751 Gene denotes ACE2 Gene:59272
1797 56047-56049 Gene denotes to Gene:6999
1798 55457-55459 Gene denotes to Gene:6999
1799 55412-55414 Gene denotes to Gene:6999
1800 55489-55494 Species denotes human Tax:9606
1801 55697-55705 Species denotes SARS-CoV Tax:694009
1802 55978-55988 Species denotes SARS-CoV-2 Tax:2697049
1803 56309-56319 Species denotes SARS-CoV-2 Tax:2697049
1804 55517-55525 Disease denotes COVID-19 MESH:C000657245
1805 55590-55598 Disease denotes COVID-19 MESH:C000657245
1808 56922-56924 Gene denotes to Gene:6999
1809 57042-57050 Disease denotes COVID-19 MESH:C000657245
1901 59530-59533 Gene denotes CRP Gene:1401
1902 61144-61147 Gene denotes CD4 Gene:920
1903 61150-61153 Gene denotes CD8 Gene:925
1904 61181-61184 Gene denotes CD4 Gene:920
1905 61187-61190 Gene denotes CD8 Gene:925
1906 61354-61359 Gene denotes Tim-3 Gene:84868
1907 61402-61407 Gene denotes Tim-3 Gene:84868
1908 61647-61650 Gene denotes CD4 Gene:920
1909 61655-61658 Gene denotes CD8 Gene:925
1910 61816-61821 Gene denotes CD11b Gene:3684
1911 61852-61857 Gene denotes CD163 Gene:9332
1912 61864-61869 Gene denotes CD206 Gene:4360
1913 61886-61890 Gene denotes IL-6 Gene:3569
1914 61892-61897 Gene denotes IL-10 Gene:3586
1915 61903-61908 Gene denotes TNF-α Gene:7124
1916 62024-62028 Gene denotes IL-6 Gene:3569
1917 62092-62097 Gene denotes IP-10 Gene:3627
1918 62110-62114 Gene denotes IL-1 Gene:3552
1919 62117-62122 Gene denotes IP-10 Gene:3627
1920 62135-62141 Gene denotes IL-1ra Gene:3554
1921 62309-62313 Gene denotes IL-6 Gene:3569
1922 62597-62601 Gene denotes IL-8 Gene:3576
1923 62725-62729 Gene denotes IL-8 Gene:3576
1924 62738-62743 Gene denotes IL-10 Gene:3586
1925 62956-62961 Gene denotes IL-2R Gene:3559
1926 63150-63155 Gene denotes IL-1β Gene:3552
1927 63161-63166 Gene denotes IL-1β Gene:3552
1928 63330-63335 Gene denotes IL-1β Gene:3552
1929 63465-63474 Gene denotes IL-4 IL-4 Gene:3565
1930 63610-63615 Gene denotes IL-18 Gene:3606
1931 63712-63717 Gene denotes IL-18 Gene:3606
1932 63856-63861 Gene denotes IFN-γ Gene:3458
1933 63925-63931 Gene denotes GM-CSF Gene:1437
1934 64029-64033 Gene denotes IL-2 Gene:3558
1935 64053-64058 Gene denotes IFN-γ Gene:3458
1936 59431-59434 Gene denotes CRP Gene:1401
1937 62797-62799 Gene denotes to Gene:6999
1938 61486-61488 Gene denotes to Gene:6999
1939 60916-60918 Gene denotes to Gene:6999
1940 60591-60593 Gene denotes to Gene:6999
1941 59952-59954 Gene denotes to Gene:6999
1942 59311-59313 Gene denotes to Gene:6999
1943 59260-59262 Gene denotes to Gene:6999
1944 59117-59119 Gene denotes to Gene:6999
1945 59087-59089 Gene denotes to Gene:6999
1946 59069-59071 Gene denotes to Gene:6999
1947 58694-58702 Species denotes patients Tax:9606
1948 58996-59004 Species denotes patients Tax:9606
1949 59031-59039 Species denotes Patients Tax:9606
1950 59227-59235 Species denotes patients Tax:9606
1951 60303-60311 Species denotes patients Tax:9606
1952 60671-60679 Species denotes patients Tax:9606
1953 60836-60844 Species denotes patients Tax:9606
1954 61451-61459 Species denotes patients Tax:9606
1955 61571-61579 Species denotes patients Tax:9606
1956 61630-61638 Species denotes patients Tax:9606
1957 61928-61936 Species denotes patients Tax:9606
1958 62061-62069 Species denotes patients Tax:9606
1959 62776-62784 Species denotes patients Tax:9606
1960 62805-62813 Species denotes patients Tax:9606
1961 63209-63217 Species denotes patients Tax:9606
1962 63435-63443 Species denotes patients Tax:9606
1963 63702-63710 Species denotes patients Tax:9606
1964 63905-63913 Species denotes patients Tax:9606
1965 63966-63974 Species denotes patients Tax:9606
1966 64172-64182 Species denotes SARS-CoV-2 Tax:2697049
1967 64135-64145 Species denotes SARS-CoV-2 Tax:2697049
1968 64288-64298 Species denotes SARS-CoV-2 Tax:2697049
1969 60717-60726 Chemical denotes NT-proBNP
1970 60771-60780 Chemical denotes NT-proBNP
1971 59250-59259 Disease denotes pneumonia MESH:D011014
1972 59270-59279 Disease denotes pneumonia MESH:D011014
1973 59340-59348 Disease denotes COVID-19 MESH:C000657245
1974 59573-59585 Disease denotes lung lesions MESH:D008171
1975 59810-59827 Disease denotes myocardial injury MESH:D009202
1976 59980-59988 Disease denotes COVID-19 MESH:C000657245
1977 60204-60242 Disease denotes disseminated intravascular coagulation MESH:D004211
1978 60330-60344 Disease denotes cardiac injury MESH:D006331
1979 60827-60832 Disease denotes death MESH:D003643
1980 60857-60865 Disease denotes COVID-19 MESH:C000657245
1981 60989-61005 Disease denotes Thrombocytopenia MESH:D013921
1982 61061-61078 Disease denotes myocardial injury MESH:D009202
1983 61082-61090 Disease denotes COVID-19 MESH:C000657245
1984 61243-61251 Disease denotes COVID-19 MESH:C000657245
1985 61562-61570 Disease denotes infected MESH:D007239
1986 62252-62260 Disease denotes COVID-19 MESH:C000657245
1987 62556-62575 Disease denotes respiratory failure MESH:D012131
1988 63111-63119 Disease denotes COVID-19 MESH:C000657245
1989 63495-63516 Disease denotes impaired lung lesions MESH:D009422
1990 63693-63701 Disease denotes COVID-19 MESH:C000657245
1991 63957-63965 Disease denotes COVID-19 MESH:C000657245
1993 58559-58567 Disease denotes COVID-19 MESH:C000657245
1996 64398-64402 Gene denotes ACE2 Gene:59272
1997 64466-64474 Disease denotes COVID-19 MESH:C000657245
2005 64554-64558 Gene denotes ACE2 Gene:59272
2006 64705-64709 Gene denotes ACE2 Gene:59272
2007 64775-64779 Gene denotes ACE2 Gene:59272
2008 64944-64948 Gene denotes ACE2 Gene:59272
2009 65019-65021 Gene denotes to Gene:6999
2010 64915-64917 Gene denotes to Gene:6999
2011 64902-64914 Disease denotes liver injury MESH:D017093
2018 65033-65037 Gene denotes ACE2 Gene:59272
2019 65039-65070 Gene denotes angiotensin-converting enzyme 2 Gene:59272
2020 65072-65075 Gene denotes BNP Gene:4879
2021 65105-65108 Gene denotes CRP Gene:1401
2022 65110-65128 Gene denotes C-reactive protein Gene:1401
2023 65163-65165 Gene denotes to Gene:6999
2051 57761-57779 Gene denotes C-reactive protein Gene:1401
2052 57781-57784 Gene denotes CRP Gene:1401
2053 57834-57837 Gene denotes CRP Gene:1401
2054 58011-58015 Gene denotes IL-6 Gene:3569
2055 58091-58101 Gene denotes cystatin C Gene:1471
2056 58125-58139 Gene denotes cholinesterase Gene:590
2057 58458-58462 Gene denotes ACE2 Gene:59272
2058 57466-57469 Gene denotes aid Gene:57379
2059 58422-58424 Gene denotes to Gene:6999
2060 58243-58245 Gene denotes to Gene:6999
2061 57893-57895 Gene denotes to Gene:6999
2062 57858-57860 Gene denotes to Gene:6999
2063 57845-57847 Gene denotes to Gene:6999
2064 57644-57646 Gene denotes to Gene:6999
2065 57463-57465 Gene denotes to Gene:6999
2066 57396-57398 Gene denotes to Gene:6999
2067 57408-57416 Species denotes patients Tax:9606
2068 57604-57612 Species denotes patients Tax:9606
2069 57870-57878 Species denotes patients Tax:9606
2070 58393-58401 Species denotes patients Tax:9606
2071 58073-58077 Chemical denotes urea MESH:D014508
2072 58079-58089 Chemical denotes creatinine MESH:D003404
2073 58110-58119 Chemical denotes bilirubin MESH:D001663
2074 57861-57869 Disease denotes COVID-19 MESH:C000657245
2075 57902-57918 Disease denotes viral infections MESH:D001102
2076 58223-58231 Disease denotes COVID-19 MESH:C000657245
2077 58384-58392 Disease denotes COVID-19 MESH:C000657245
2096 65792-65795 Gene denotes CRP Gene:1401
2097 66193-66196 Gene denotes CRP Gene:1401
2098 66036-66038 Gene denotes to Gene:6999
2099 65808-65810 Gene denotes to Gene:6999
2100 65352-65354 Gene denotes to Gene:6999
2101 65514-65522 Species denotes patients Tax:9606
2102 65768-65776 Species denotes patients Tax:9606
2103 66012-66020 Species denotes patients Tax:9606
2104 66060-66068 Species denotes patients Tax:9606
2105 66622-66630 Species denotes patients Tax:9606
2106 65251-65262 Disease denotes Lymphopenia MESH:D008231
2107 65317-65325 Disease denotes COVID-19 MESH:C000657245
2108 65377-65386 Disease denotes mortality MESH:D003643
2109 65972-65980 Disease denotes COVID-19 MESH:C000657245
2110 66328-66345 Disease denotes pulmonary thrombi MESH:D008171
2111 66429-66442 Disease denotes dysfunctional MESH:D009461
2112 66523-66539 Disease denotes thrombocytopenia MESH:D013921
2113 66613-66621 Disease denotes COVID-19 MESH:C000657245
2142 67046-67050 Gene denotes IL-6 Gene:3569
2143 67304-67309 Gene denotes IL-2R Gene:3559
2144 67311-67315 Gene denotes IL-8 Gene:3576
2145 67317-67322 Gene denotes IL-10 Gene:3586
2146 67328-67334 Gene denotes GM-CSF Gene:1437
2147 67575-67580 Gene denotes IL-1β Gene:3552
2148 67585-67589 Gene denotes IL-4 Gene:3565
2149 67785-67789 Gene denotes IL-6 Gene:3569
2150 67791-67796 Gene denotes IL-10 Gene:3586
2151 67798-67803 Gene denotes IL-18 Gene:3606
2152 67805-67810 Gene denotes CTACK Gene:10850
2153 67816-67821 Gene denotes IFN-γ Gene:3458
2154 67995-68000 Gene denotes IP-10 Gene:3627
2155 68013-68019 Gene denotes IL-1ra Gene:3554
2156 68060-68064 Gene denotes IL-6 Gene:3569
2157 68206-68210 Gene denotes IL-6 Gene:3569
2158 67475-67477 Gene denotes to Gene:6999
2159 67088-67096 Species denotes patients Tax:9606
2160 67124-67132 Species denotes patients Tax:9606
2161 67455-67463 Species denotes patients Tax:9606
2162 67746-67754 Species denotes patients Tax:9606
2163 66892-66901 Disease denotes mortality MESH:D003643
2164 66907-66915 Disease denotes COVID-19 MESH:C000657245
2165 66994-67002 Disease denotes COVID-19 MESH:C000657245
2166 67109-67123 Disease denotes critically ill MESH:D016638
2167 67192-67211 Disease denotes respiratory failure MESH:D012131
2168 67737-67745 Disease denotes COVID-19 MESH:C000657245
2169 68099-68118 Disease denotes respiratory failure MESH:D012131
2179 68823-68825 Gene denotes to Gene:6999
2180 68412-68414 Gene denotes to Gene:6999
2181 68485-68493 Species denotes patients Tax:9606
2182 68778-68786 Species denotes patients Tax:9606
2183 68826-68834 Species denotes patients Tax:9606
2184 68445-68450 Disease denotes death MESH:D003643
2185 68476-68484 Disease denotes COVID-19 MESH:C000657245
2186 68791-68795 Disease denotes died MESH:D003643
2187 68801-68810 Disease denotes infection MESH:D007239
2194 69500-69502 Gene denotes to Gene:6999
2195 69307-69309 Gene denotes to Gene:6999
2196 69082-69090 Species denotes patients Tax:9606
2197 69463-69470 Species denotes patient Tax:9606
2198 69573-69582 Disease denotes mortality MESH:D003643
2199 69586-69594 Disease denotes COVID-19 MESH:C000657245
2210 70166-70170 Gene denotes ACE2 Gene:59272
2211 70163-70165 Gene denotes to Gene:6999
2212 69985-69987 Gene denotes to Gene:6999
2213 70146-70156 Species denotes SARS-CoV-2 Tax:2697049
2214 69714-69725 Disease denotes lymphopenia MESH:D008231
2215 69793-69817 Disease denotes blood hypercoagulability MESH:D007022
2216 69838-69846 Disease denotes COVID-19 MESH:C000657245
2217 70269-70281 Disease denotes inflammation MESH:D007249
2218 70432-70443 Disease denotes lymphopenia MESH:D008231
2219 70458-70484 Disease denotes atrophy of lymphoid organs MESH:D000072717
2225 70870-70880 Species denotes SARS-CoV-2 Tax:2697049
2226 70930-70938 Species denotes SARS-CoV Tax:694009
2227 70942-70950 Species denotes MERS-CoV Tax:1335626
2228 70969-70980 Species denotes DNA viruses Tax:2080735
2229 70788-70804 Disease denotes viral infections MESH:D001102
2260 71378-71383 Gene denotes DHODH Gene:1723
2261 71990-71992 Gene denotes to Gene:6999
2262 71899-71901 Gene denotes to Gene:6999
2263 71727-71729 Gene denotes to Gene:6999
2264 71442-71444 Gene denotes to Gene:6999
2265 71081-71086 Species denotes human Tax:9606
2266 71144-71154 Species denotes SARS-CoV-2 Tax:2697049
2267 71251-71255 Species denotes mice Tax:10090
2268 71270-71280 Species denotes SARS-CoV-2 Tax:2697049
2269 71453-71463 Species denotes SARS-CoV-2 Tax:2697049
2270 71739-71749 Species denotes SARS-CoV-2 Tax:2697049
2271 71954-71959 Species denotes human Tax:9606
2272 71960-71963 Species denotes CoV Tax:11118
2273 71964-71973 Species denotes HCoV-NL63 Tax:277944
2274 72001-72009 Species denotes MERS-CoV Tax:1335626
2275 72026-72036 Species denotes SARS-CoV-2 Tax:2697049
2276 72040-72045 Species denotes human Tax:9606
2277 71160-71174 Chemical denotes ribonucleoside MESH:D012263
2278 71182-71204 Chemical denotes β-D-N4-hydroxycytidine MESH:C010737
2279 71206-71209 Chemical denotes NHC MESH:C010737
2280 71411-71421 Chemical denotes pyrimidine MESH:C030986
2281 71507-71517 Chemical denotes remdesivir MESH:C000606551
2282 71521-71532 Chemical denotes chloroquine MESH:D002738
2283 71575-71586 Chemical denotes Merimepodib MESH:C407002
2284 71695-71704 Chemical denotes guanosine MESH:D006151
2285 71806-71863 Chemical denotes N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride
2286 71865-71869 Chemical denotes HTCC
2287 71236-71247 Disease denotes lung injury MESH:D055370
2288 71256-71264 Disease denotes infected MESH:D007239
2289 71921-71930 Disease denotes infection MESH:D007239
2313 72254-72258 Gene denotes Mpro Gene:8673700
2314 72396-72400 Gene denotes Mpro Gene:8673700
2315 72716-72718 Gene denotes to Gene:6999
2316 72683-72685 Gene denotes to Gene:6999
2317 72501-72505 Gene denotes Mpro Gene:8673700
2318 72316-72320 Gene denotes Mpro Gene:8673700
2319 72198-72208 Species denotes SARS-CoV-2 Tax:2697049
2320 72305-72315 Species denotes SARS-CoV-2 Tax:2697049
2321 72490-72500 Species denotes SARS-CoV-2 Tax:2697049
2322 72726-72736 Species denotes SARS-CoV-2 Tax:2697049
2323 72964-72974 Species denotes SARS-CoV-2 Tax:2697049
2324 72784-72794 Chemical denotes nelfinavir MESH:D019888
2325 72796-72805 Chemical denotes lopinavir MESH:D061466
2326 72807-72816 Chemical denotes ritonavir MESH:D019438
2327 72818-72828 Chemical denotes saquinavir MESH:D019258
2328 72830-72840 Chemical denotes atazanavir MESH:D000069446
2329 72842-72852 Chemical denotes tipranavir MESH:C107201
2330 72854-72864 Chemical denotes amprenavir MESH:C095108
2331 72866-72875 Chemical denotes darunavir MESH:D000069454
2332 72881-72890 Chemical denotes indinavir MESH:D019469
2333 73004-73014 Chemical denotes nelfinavir MESH:D019888
2334 72618-72626 Disease denotes toxicity MESH:D064420
2335 72950-72958 Disease denotes infected MESH:D007239
2337 73069-73073 Gene denotes RdRp Gene:43740578
2341 74142-74144 Gene denotes to Gene:6999
2342 74103-74105 Gene denotes to Gene:6999
2343 74113-74121 Disease denotes COVID-19 MESH:C000657245
2349 74173-74177 Gene denotes Rdrp Gene:43740578
2350 74190-74200 Chemical denotes remdesivir MESH:C000606551
2351 74202-74213 Chemical denotes favipiravir MESH:C462182
2352 74237-74256 Chemical denotes lopinavir/ritonavir MESH:C558899
2353 74361-74382 Disease denotes SARS-CoV-2 infections MESH:C000657245
2357 74614-74619 Gene denotes CTLA4 Gene:1493
2358 74388-74390 Chemical denotes CQ MESH:D002738
2359 74395-74398 Chemical denotes HCQ MESH:D006886
2365 74659-74663 Gene denotes IL-6 Gene:3569
2366 74813-74819 Gene denotes GM-CSF Gene:1437
2367 74836-74838 Gene denotes to Gene:6999
2368 74752-74754 Gene denotes to Gene:6999
2369 74763-74771 Disease denotes COVID-19 MESH:C000657245
2373 75105-75113 Species denotes patients Tax:9606
2374 74931-74941 Species denotes SARS-CoV-2 Tax:2697049
2375 75096-75104 Disease denotes COVID-19 MESH:C000657245
2383 75115-75121 Gene denotes GM-CSF Gene:1437
2384 75123-75171 Gene denotes granulocyte-macrophage colony-stimulating factor Gene:1437
2385 75215-75219 Gene denotes RdRp Gene:43740578
2386 75173-75175 Chemical denotes CQ MESH:D002738
2387 75177-75188 Chemical denotes chloroquine MESH:D002738
2388 75190-75193 Chemical denotes HCQ MESH:D006886
2389 75195-75213 Chemical denotes hydroxychloroquine MESH:D006886
2405 73123-73127 Gene denotes RdRp Gene:43740578
2406 73329-73333 Gene denotes RdRp Gene:43740578
2407 73535-73537 Gene denotes to Gene:6999
2408 73559-73567 Species denotes MERS-CoV Tax:1335626
2409 73732-73747 Species denotes rhesus macaques Tax:9544
2410 73274-73284 Chemical denotes Remdesivir MESH:C000606551
2411 73289-73298 Chemical denotes adenosine MESH:D000241
2412 73498-73508 Chemical denotes Remdesivir MESH:C000606551
2413 73704-73714 Chemical denotes remdesivir MESH:C000606551
2414 73824-73834 Chemical denotes remdesivir MESH:C000606551
2415 74001-74011 Chemical denotes remdesivir MESH:C000606551
2416 73572-73593 Disease denotes SARS-CoV-1 infections MESH:C000657245
2417 73753-73774 Disease denotes SARS-CoV-2 infections MESH:C000657245
2418 73878-73887 Disease denotes pneumonia MESH:D011014
2419 74041-74062 Disease denotes SARS-CoV-2 infections MESH:C000657245
2440 75621-75625 Gene denotes RdRp Gene:43740578
2441 75925-75927 Gene denotes to Gene:6999
2442 75846-75848 Gene denotes to Gene:6999
2443 75641-75643 Gene denotes to Gene:6999
2444 75803-75811 Species denotes patients Tax:9606
2445 76082-76090 Species denotes patients Tax:9606
2446 75657-75666 Species denotes influenza Tax:11520
2447 75454-75461 Chemical denotes arbidol MESH:C086979
2448 75463-75473 Chemical denotes umifenovir MESH:C086979
2449 75529-75548 Chemical denotes lopinavir/ritonavir MESH:C558899
2450 75550-75555 Chemical denotes LPV/r MESH:C558899
2451 75605-75616 Chemical denotes favipiravir MESH:C462182
2452 75709-75719 Chemical denotes remdesivir MESH:C000606551
2453 75854-75865 Chemical denotes favipiravir MESH:C462182
2454 75869-75876 Chemical denotes arbidol MESH:C086979
2455 75899-75910 Chemical denotes Favipiravir MESH:C462182
2456 75667-75677 Disease denotes infections MESH:D007239
2457 75827-75835 Disease denotes COVID-19 MESH:C000657245
2458 75836-75845 Disease denotes infection MESH:D007239
2459 76106-76114 Disease denotes COVID-19 MESH:C000657245
2480 77099-77101 Gene denotes to Gene:6999
2481 76552-76554 Gene denotes to Gene:6999
2482 76455-76457 Gene denotes to Gene:6999
2483 76197-76205 Species denotes SARS-Cov Tax:694009
2484 76247-76257 Species denotes SARS-Cov-2 Tax:2697049
2485 76296-76304 Species denotes patients Tax:9606
2486 76385-76393 Species denotes patients Tax:9606
2487 76528-76536 Species denotes patients Tax:9606
2488 76742-76750 Species denotes patients Tax:9606
2489 76149-76154 Chemical denotes LPV/r MESH:C558899
2490 76371-76376 Chemical denotes LPV/r MESH:C558899
2491 76396-76403 Chemical denotes arbidol MESH:C086979
2492 76582-76587 Chemical denotes LPV/r MESH:C558899
2493 76589-76596 Chemical denotes arbidol MESH:C086979
2494 76792-76797 Chemical denotes LPV/r MESH:C558899
2495 76898-76903 Chemical denotes LPV/r MESH:C558899
2496 76944-76949 Chemical denotes LPV/r MESH:C558899
2497 77062-77067 Chemical denotes LPV/r MESH:C558899
2498 76467-76475 Disease denotes COVID-19 MESH:C000657245
2499 76733-76741 Disease denotes COVID-19 MESH:C000657245
2529 78324-78326 Gene denotes to Gene:6999
2530 78308-78310 Gene denotes to Gene:6999
2531 78161-78163 Gene denotes to Gene:6999
2532 78126-78128 Gene denotes to Gene:6999
2533 77896-77898 Gene denotes to Gene:6999
2534 77823-77825 Gene denotes to Gene:6999
2535 77553-77555 Gene denotes to Gene:6999
2536 77233-77241 Species denotes patients Tax:9606
2537 77246-77254 Species denotes patients Tax:9606
2538 77357-77365 Species denotes patients Tax:9606
2539 77694-77702 Species denotes patients Tax:9606
2540 77799-77807 Species denotes patients Tax:9606
2541 78086-78094 Species denotes patients Tax:9606
2542 78550-78558 Species denotes patients Tax:9606
2543 77203-77213 Chemical denotes remdesivir MESH:C000606551
2544 77298-77308 Chemical denotes remdesivir MESH:C000606551
2545 77379-77389 Chemical denotes remdesivir MESH:C000606551
2546 77444-77450 Chemical denotes oxygen MESH:D010100
2547 77572-77582 Chemical denotes remdesivir MESH:C000606551
2548 77826-77836 Chemical denotes remdesivir MESH:C000606551
2549 78115-78125 Chemical denotes remdesevir
2550 78327-78337 Chemical denotes remdesivir MESH:C000606551
2551 78514-78524 Chemical denotes remdesivir MESH:C000606551
2552 77224-77232 Disease denotes COVID-19 MESH:C000657245
2553 77790-77798 Disease denotes COVID-19 MESH:C000657245
2554 78021-78028 Disease denotes Allergy MESH:D004342
2555 78033-78052 Disease denotes Infectious Diseases MESH:D003141
2556 78250-78259 Disease denotes mortality MESH:D003643
2557 78541-78549 Disease denotes COVID-19 MESH:C000657245
2559 78594-78602 Disease denotes COVID-19 MESH:C000657245
2561 78614-78625 Chemical denotes Chloroquine MESH:D002738
2602 79280-79284 Gene denotes TLR7 Gene:51284
2603 79289-79293 Gene denotes TLR9 Gene:54106
2604 80367-80369 Gene denotes to Gene:6999
2605 80240-80242 Gene denotes to Gene:6999
2606 80136-80138 Gene denotes to Gene:6999
2607 80093-80095 Gene denotes To Gene:6999
2608 79150-79152 Gene denotes to Gene:6999
2609 78933-78935 Gene denotes to Gene:6999
2610 79024-79032 Species denotes SARS-CoV Tax:694009
2611 79520-79530 Species denotes SARS-CoV-2 Tax:2697049
2612 80264-80274 Species denotes SARS-CoV-2 Tax:2697049
2613 80284-80292 Species denotes patients Tax:9606
2614 80417-80425 Species denotes patients Tax:9606
2615 80650-80660 Species denotes SARS-CoV-2 Tax:2697049
2616 78668-78679 Chemical denotes Chloroquine MESH:D002738
2617 78681-78683 Chemical denotes CQ MESH:D002738
2618 78704-78722 Chemical denotes hydroxychloroquine MESH:D006886
2619 78724-78727 Chemical denotes HCQ MESH:D006886
2620 78922-78924 Chemical denotes CQ MESH:D002738
2621 78929-78932 Chemical denotes HCQ MESH:D006886
2622 79082-79084 Chemical denotes CQ MESH:D002738
2623 79089-79092 Chemical denotes HCQ MESH:D006886
2624 79184-79186 Chemical denotes CQ MESH:D002738
2625 79554-79556 Chemical denotes CQ MESH:D002738
2626 79561-79564 Chemical denotes HCQ MESH:D006886
2627 79740-79742 Chemical denotes CQ MESH:D002738
2628 79763-79766 Chemical denotes HCQ MESH:D006886
2629 79916-79919 Chemical denotes HCQ MESH:D006886
2630 80036-80039 Chemical denotes HCQ MESH:D006886
2631 80227-80230 Chemical denotes HCQ MESH:D006886
2632 80335-80338 Chemical denotes HCQ MESH:D006886
2633 80571-80574 Chemical denotes HCQ MESH:D006886
2634 80628-80631 Chemical denotes HCQ MESH:D006886
2635 78779-78787 Disease denotes COVID-19 MESH:C000657245
2636 78870-78892 Disease denotes rheumatologic diseases MESH:D012216
2637 78936-78944 Disease denotes COVID-19 MESH:C000657245
2638 79491-79500 Disease denotes infection MESH:D007239
2639 79896-79904 Disease denotes infected MESH:D007239
2640 79938-79947 Disease denotes infection MESH:D007239
2641 80408-80416 Disease denotes COVID-19 MESH:C000657245
2643 80700-80703 Chemical denotes HCQ MESH:D006886
2691 82905-82923 Gene denotes C-reactive protein Gene:1401
2692 83127-83129 Gene denotes to Gene:6999
2693 82682-82684 Gene denotes to Gene:6999
2694 82477-82479 Gene denotes to Gene:6999
2695 82358-82360 Gene denotes to Gene:6999
2696 82054-82056 Gene denotes to Gene:6999
2697 82027-82029 Gene denotes to Gene:6999
2698 81434-81436 Gene denotes to Gene:6999
2699 80782-80784 Gene denotes to Gene:6999
2700 81068-81076 Species denotes patients Tax:9606
2701 81242-81250 Species denotes patients Tax:9606
2702 81296-81304 Species denotes patients Tax:9606
2703 81567-81575 Species denotes patients Tax:9606
2704 81823-81831 Species denotes patients Tax:9606
2705 81914-81922 Species denotes patients Tax:9606
2706 82007-82015 Species denotes patients Tax:9606
2707 82062-82070 Species denotes patients Tax:9606
2708 82124-82132 Species denotes patients Tax:9606
2709 82249-82257 Species denotes patients Tax:9606
2710 82498-82506 Species denotes patients Tax:9606
2711 82694-82704 Species denotes SARS-CoV-2 Tax:2697049
2712 82931-82939 Species denotes patients Tax:9606
2713 83130-83138 Species denotes patients Tax:9606
2714 80771-80774 Chemical denotes HCQ MESH:D006886
2715 80779-80781 Chemical denotes CQ MESH:D002738
2716 81049-81052 Chemical denotes HCQ MESH:D006886
2717 81097-81100 Chemical denotes HCQ MESH:D006886
2718 81146-81158 Chemical denotes azithromycin MESH:D017963
2719 81160-81162 Chemical denotes AZ MESH:D017963
2720 81264-81267 Chemical denotes HCQ MESH:D006886
2721 81272-81274 Chemical denotes AZ MESH:D017963
2722 81639-81642 Chemical denotes HCQ MESH:D006886
2723 81718-81721 Chemical denotes HCQ MESH:D006886
2724 81881-81884 Chemical denotes HCQ MESH:D006886
2725 81936-81939 Chemical denotes HCQ MESH:D006886
2726 82178-82181 Chemical denotes HCQ MESH:D006886
2727 82570-82573 Chemical denotes HCQ MESH:D006886
2728 82812-82815 Chemical denotes HCQ MESH:D006886
2729 82953-82956 Chemical denotes HCQ MESH:D006886
2730 83174-83177 Chemical denotes HCQ MESH:D006886
2731 80791-80799 Disease denotes COVID-19 MESH:C000657245
2732 80922-80930 Disease denotes COVID-19 MESH:C000657245
2733 81059-81067 Disease denotes COVID-19 MESH:C000657245
2734 81759-81767 Disease denotes COVID-19 MESH:C000657245
2735 82143-82151 Disease denotes COVID-19 MESH:C000657245
2736 82361-82366 Disease denotes fever MESH:D005334
2737 82517-82525 Disease denotes COVID-19 MESH:C000657245
2755 84003-84005 Gene denotes to Gene:6999
2756 83809-83811 Gene denotes to Gene:6999
2757 83302-83310 Species denotes patients Tax:9606
2758 83392-83400 Species denotes patients Tax:9606
2759 83455-83463 Species denotes patients Tax:9606
2760 83554-83562 Species denotes patients Tax:9606
2761 83612-83620 Species denotes patients Tax:9606
2762 84113-84121 Species denotes patients Tax:9606
2763 83240-83243 Chemical denotes HCQ MESH:D006886
2764 83335-83338 Chemical denotes HCQ MESH:D006886
2765 83357-83359 Chemical denotes AZ MESH:D017963
2766 83636-83639 Chemical denotes HCQ MESH:D006886
2767 84031-84039 Chemical denotes HCQ ± AZ
2768 83263-83271 Disease denotes COVID-19 MESH:C000657245
2769 83440-83445 Disease denotes death MESH:D003643
2770 83575-83583 Disease denotes COVID-19 MESH:C000657245
2771 84044-84052 Disease denotes COVID-19 MESH:C000657245
2773 84399-84407 Disease denotes COVID-19 MESH:C000657245
2791 84810-84812 Gene denotes CS Gene:1431
2792 84585-84587 Gene denotes CS Gene:1431
2793 85018-85020 Gene denotes CS Gene:1431
2794 84739-84747 Species denotes patients Tax:9606
2795 84753-84761 Species denotes MERS-CoV Tax:1335626
2796 84763-84771 Species denotes SARS-CoV Tax:694009
2797 84959-84967 Species denotes patients Tax:9606
2798 85057-85065 Species denotes patients Tax:9606
2799 85220-85228 Species denotes patients Tax:9606
2800 84511-84515 Disease denotes ARDS MESH:D012128
2801 84778-84798 Disease denotes SARS-CoV-2 infection MESH:C000657245
2802 84850-84859 Disease denotes mortality MESH:D003643
2803 84923-84943 Disease denotes SARS-CoV-2 infection MESH:C000657245
2804 84981-84990 Disease denotes mortality MESH:D003643
2805 85071-85075 Disease denotes ARDS MESH:D012128
2806 85373-85381 Disease denotes COVID-19 MESH:C000657245
2807 85437-85445 Disease denotes COVID-19 MESH:C000657245
2839 87196-87198 Gene denotes CS Gene:1431
2840 86108-86110 Gene denotes CS Gene:1431
2841 87341-87343 Gene denotes to Gene:6999
2842 86897-86899 Gene denotes to Gene:6999
2843 86297-86299 Gene denotes to Gene:6999
2844 86071-86073 Gene denotes to Gene:6999
2845 86042-86044 Gene denotes to Gene:6999
2846 85795-85797 Gene denotes to Gene:6999
2847 85767-85769 Gene denotes to Gene:6999
2848 85516-85518 Gene denotes to Gene:6999
2849 85543-85551 Species denotes patients Tax:9606
2850 85737-85745 Species denotes patients Tax:9606
2851 85846-85854 Species denotes patients Tax:9606
2852 85999-86007 Species denotes patients Tax:9606
2853 86225-86233 Species denotes patients Tax:9606
2854 86420-86428 Species denotes patients Tax:9606
2855 86517-86525 Species denotes patients Tax:9606
2856 86753-86761 Species denotes patients Tax:9606
2857 87395-87403 Species denotes patients Tax:9606
2858 85565-85583 Chemical denotes methylprednisolone MESH:D008775
2859 85878-85896 Chemical denotes methylprednisolone MESH:D008775
2860 86788-86806 Chemical denotes methylprednisolone MESH:D008775
2861 86943-86949 Chemical denotes oxygen MESH:D010100
2862 85860-85864 Disease denotes ARDS MESH:D012128
2863 85909-85918 Disease denotes mortality MESH:D003643
2864 86443-86451 Disease denotes COVID-19 MESH:C000657245
2865 86485-86494 Disease denotes mortality MESH:D003643
2866 86531-86535 Disease denotes ARDS MESH:D012128
2867 86708-86717 Disease denotes mortality MESH:D003643
2868 86900-86905 Disease denotes fever MESH:D005334
2869 87206-87214 Disease denotes COVID-19 MESH:C000657245
2871 87545-87553 Disease denotes COVID-19 MESH:C000657245
2873 87555-87566 Species denotes Recombinant Tax:575864
2879 87807-87813 Gene denotes IFNα/β Gene:3440
2880 87733-87735 Gene denotes to Gene:6999
2881 87630-87635 Species denotes human Tax:9606
2882 87666-87676 Species denotes SARS-CoV-2 Tax:2697049
2883 88224-88236 Disease denotes inflammation MESH:D007249
2902 89441-89450 Gene denotes IFN-I/III
2903 89320-89322 Gene denotes to Gene:6999
2904 89275-89277 Gene denotes to Gene:6999
2905 89166-89168 Gene denotes to Gene:6999
2906 89106-89108 Gene denotes to Gene:6999
2907 88405-88407 Gene denotes to Gene:6999
2908 88514-88529 Species denotes betacoronavirus Tax:694002
2909 88558-88566 Species denotes patients Tax:9606
2910 88791-88799 Species denotes patients Tax:9606
2911 89109-89119 Species denotes SARS-CoV-2 Tax:2697049
2912 89131-89141 Species denotes SARS-CoV-2 Tax:2697049
2913 89185-89193 Species denotes SARS-CoV Tax:694009
2914 89278-89295 Species denotes betacoronaviruses Tax:694002
2915 88778-88787 Chemical denotes ribavirin MESH:D012254
2916 88416-88424 Disease denotes COVID-19 MESH:C000657245
2917 88530-88540 Disease denotes infections MESH:D007239
2918 88572-88592 Disease denotes SARS-CoV-1 infection MESH:C000657245
2919 88805-88823 Disease denotes MERS-CoV infection MESH:D018352
2927 89618-89635 Gene denotes IL-6, -8, and -10 Gene:3569
2928 90091-90095 Gene denotes ACE2 Gene:59272
2929 89850-89852 Gene denotes to Gene:6999
2930 89653-89655 Gene denotes to Gene:6999
2931 90001-90009 Species denotes patients Tax:9606
2932 90070-90080 Species denotes SARS-CoV-2 Tax:2697049
2933 89671-89679 Disease denotes COVID-19 MESH:C000657245
2960 90343-90346 Gene denotes CD4 Gene:920
2961 90368-90374 Gene denotes GM-CSF Gene:1437
2962 90379-90383 Gene denotes IL-6 Gene:3569
2963 90564-90569 Gene denotes TNF-α Gene:7124
2964 90571-90576 Gene denotes IFN-ɣ Gene:3458
2965 90578-90582 Gene denotes IL-2 Gene:3558
2966 90600-90604 Gene denotes CCL2 Gene:6347
2967 90606-90610 Gene denotes CCL3 Gene:6348
2968 90612-90616 Gene denotes CCL4 Gene:6351
2969 90667-90672 Gene denotes TH1/2 Gene:51497
2970 90204-90206 Gene denotes to Gene:6999
2971 90152-90154 Gene denotes to Gene:6999
2972 90247-90255 Species denotes patients Tax:9606
2973 90421-90429 Species denotes patients Tax:9606
2974 90447-90455 Species denotes patients Tax:9606
2975 91039-91054 Species denotes betacoronavirus Tax:694002
2976 91077-91085 Species denotes SARS-CoV Tax:694009
2977 91092-91100 Species denotes MERS-CoV Tax:1335626
2978 91234-91240 Species denotes humans Tax:9606
2979 90238-90246 Disease denotes COVID-19 MESH:C000657245
2980 90311-90322 Disease denotes lymphopenia MESH:D008231
2981 90412-90420 Disease denotes COVID-19 MESH:C000657245
2982 90438-90446 Disease denotes COVID-19 MESH:C000657245
2983 90684-90692 Disease denotes COVID-19 MESH:C000657245
2984 90879-90887 Disease denotes COVID-19 MESH:C000657245
2985 91055-91065 Disease denotes infections MESH:D007239
2990 93410-93413 Gene denotes AID Gene:57379
2991 93406-93409 Species denotes COV Tax:11118
2992 93046-93056 Disease denotes TOCOVID-19 MESH:C000657245
2993 93415-93452 Disease denotes tocilizumabsiltuximabanakinrastandard
2996 92915-92919 Gene denotes IL-6 Gene:3569
2997 92920-92925 Gene denotes IL-6R Gene:3570
3024 91434-91438 Gene denotes IL-6 Gene:3569
3025 91528-91532 Gene denotes IL-6 Gene:3569
3026 91652-91657 Gene denotes IL-6R Gene:3570
3027 91728-91732 Gene denotes IL-6 Gene:3569
3028 91878-91880 Gene denotes To Gene:6999
3029 91964-91972 Species denotes patients Tax:9606
3030 92218-92226 Species denotes patients Tax:9606
3031 92272-92280 Species denotes patients Tax:9606
3032 92303-92311 Species denotes patients Tax:9606
3033 92333-92341 Species denotes patients Tax:9606
3034 92595-92603 Species denotes patients Tax:9606
3035 91669-91680 Chemical denotes tocilizumab MESH:C502936
3036 91695-91704 Chemical denotes sarilumab MESH:C000592401
3037 91706-91713 Chemical denotes Kevzara MESH:C000592401
3038 92013-92024 Chemical denotes tocilizumab MESH:C502936
3039 92052-92061 Chemical denotes lopinavir MESH:D061466
3040 92063-92081 Chemical denotes methylprednisolone MESH:D008775
3041 92087-92093 Chemical denotes oxygen MESH:D010100
3042 92492-92503 Chemical denotes tocilizumab MESH:C502936
3043 91465-91473 Disease denotes COVID-19 MESH:C000657245
3044 91809-91817 Disease denotes COVID-19 MESH:C000657245
3045 91826-91835 Disease denotes pneumonia MESH:D011014
3046 91955-91963 Disease denotes COVID-19 MESH:C000657245
3047 92400-92420 Disease denotes pulmonary infections MESH:D012141
3048 92616-92634 Disease denotes COVID-19 pneumonia MESH:C000657245
3049 92703-92712 Disease denotes mortality MESH:D003643
3064 93480-93484 Gene denotes IL-6 Gene:3569
3065 93565-93570 Gene denotes IL-1R Gene:3554
3066 93572-93578 Gene denotes GM-CSF Gene:1437
3067 93607-93611 Gene denotes CCR5 Gene:1234
3068 93865-93868 Gene denotes C5a Gene:728
3069 93743-93745 Gene denotes to Gene:6999
3070 93666-93668 Gene denotes to Gene:6999
3071 93473-93475 Gene denotes to Gene:6999
3072 93784-93792 Species denotes patients Tax:9606
3073 93944-93952 Species denotes patients Tax:9606
3074 93676-93684 Disease denotes COVID-19 MESH:C000657245
3075 93775-93783 Disease denotes COVID-19 MESH:C000657245
3076 93920-93934 Disease denotes critically ill MESH:D016638
3077 93935-93943 Disease denotes COVID-19 MESH:C000657245
3079 94035-94043 Disease denotes COVID-19 MESH:C000657245
3092 94283-94285 Gene denotes to Gene:6999
3093 94115-94117 Gene denotes to Gene:6999
3094 94079-94081 Gene denotes to Gene:6999
3095 94146-94156 Species denotes SARS-CoV-2 Tax:2697049
3096 94307-94315 Species denotes SARS-CoV Tax:694009
3098 94521-94531 Species denotes SARS-CoV-2 Tax:2697049
3099 94133-94137 Chemical denotes nAbs
3100 94206-94210 Chemical denotes nAbs
3101 94585-94589 Chemical denotes nAbs
3102 94635-94639 Chemical denotes nAbs
3103 94610-94620 Disease denotes infections MESH:D007239
3106 94680-94684 Chemical denotes nAbs
3107 94698-94706 Disease denotes COVID-19 MESH:C000657245
3134 95277-95281 Gene denotes ACE2 Gene:59272
3135 95397-95401 Gene denotes ACE2 Gene:59272
3136 95571-95575 Gene denotes ACE2 Gene:59272
3137 95830-95834 Gene denotes ACE2 Gene:59272
3138 96105-96107 Gene denotes to Gene:6999
3139 96093-96095 Gene denotes to Gene:6999
3140 95786-95788 Gene denotes to Gene:6999
3141 95520-95522 Gene denotes to Gene:6999
3142 95360-95362 Gene denotes to Gene:6999
3143 95033-95035 Gene denotes to Gene:6999
3144 94915-94917 Gene denotes to Gene:6999
3145 94716-94724 Species denotes Patients Tax:9606
3146 95342-95352 Species denotes SARS-CoV-2 Tax:2697049
3147 95505-95513 Species denotes patients Tax:9606
3148 95621-95629 Species denotes SARS-CoV Tax:694009
3149 95727-95737 Species denotes SARS-CoV-2 Tax:2697049
3150 95800-95810 Species denotes SARS-CoV-2 Tax:2697049
3151 95923-95933 Species denotes SARS-CoV-2 Tax:2697049
3152 96004-96014 Species denotes SARS-CoV-2 Tax:2697049
3153 96096-96104 Species denotes patients Tax:9606
3154 95044-95055 Species denotes recombinant Tax:575864
3155 94798-94802 Chemical denotes nAbs
3156 94931-94935 Chemical denotes nAbs
3157 95992-95995 Chemical denotes nAb
3158 94749-94769 Disease denotes SARS-CoV-2 infection MESH:C000657245
3159 96122-96131 Disease denotes infection MESH:D007239
3161 96196-96200 Chemical denotes nAbs
3184 97408-97412 Gene denotes ACE2 Gene:59272
3185 98152-98156 Gene denotes ACE2 Gene:70008
3186 98164-98168 Gene denotes ACE2 Gene:70008
3187 97457-97465 Species denotes patients Tax:9606
3188 97597-97605 Species denotes SARS-CoV Tax:694009
3189 97608-97616 Species denotes patients Tax:9606
3190 97774-97782 Species denotes SARS-CoV Tax:694009
3191 97788-97796 Species denotes MERS-CoV Tax:1335626
3192 97963-97967 Species denotes mice Tax:10090
3193 97880-97891 Species denotes recombinant Tax:575864
3194 97947-97957 Species denotes transgenic Tax:10090
3195 97479-97484 Species denotes human Tax:9606
3196 97543-97548 Species denotes human Tax:9606
3197 97628-97633 Species denotes human Tax:9606
3198 97718-97723 Species denotes human Tax:9606
3199 97892-97897 Species denotes human Tax:9606
3200 98083-98088 Species denotes mouse Tax:10090
3201 98283-98288 Species denotes human Tax:9606
3202 98393-98398 Species denotes human Tax:9606
3203 97448-97456 Disease denotes COVID-19 MESH:C000657245
3204 98373-98379 Disease denotes IVIg N MESH:C536108
3205 98399-98405 Disease denotes IVIg N MESH:C536108
3208 97293-97295 Gene denotes to Gene:6999
3209 97304-97314 Species denotes SARS-CoV-2 Tax:2697049
3229 96675-96676 Gene denotes S Gene:43740568
3230 97147-97149 Gene denotes to Gene:6999
3231 96945-96947 Gene denotes to Gene:6999
3232 96869-96871 Gene denotes to Gene:6999
3233 96228-96236 Species denotes SARS-CoV Tax:694009
3234 96243-96253 Species denotes SARS-CoV-2 Tax:2697049
3235 96341-96349 Species denotes SARS-CoV Tax:694009
3236 96399-96409 Species denotes SARS-CoV-2 Tax:2697049
3237 96664-96674 Species denotes SARS-CoV-2 Tax:2697049
3238 96736-96746 Species denotes SARS-CoV-2 Tax:2697049
3239 96953-96963 Species denotes SARS-CoV-2 Tax:2697049
3240 97027-97037 Species denotes SARS-CoV-2 Tax:2697049
3241 97184-97194 Species denotes SARS-CoV-2 Tax:2697049
3242 96352-96356 Chemical denotes nAbs
3243 96788-96792 Chemical denotes s309
3244 96918-96924 Chemical denotes CR3022
3245 97140-97146 Chemical denotes CR3022
3246 96468-96476 Disease denotes COVID-19 MESH:C000657245
3247 96593-96613 Disease denotes SARS-CoV-1 infection MESH:C000657245
3249 98523-98527 Chemical denotes nAbs
3276 99599-99603 Gene denotes ACE2 Gene:59272
3277 99740-99744 Gene denotes ACE2 Gene:59272
3278 99817-99819 Gene denotes to Gene:6999
3279 99385-99387 Gene denotes to Gene:6999
3280 99306-99308 Gene denotes to Gene:6999
3281 99122-99124 Gene denotes to Gene:93898
3282 98941-98943 Gene denotes to Gene:6999
3283 98680-98682 Gene denotes to Gene:6999
3284 98586-98588 Gene denotes to Gene:6999
3285 98611-98621 Species denotes SARS-CoV-2 Tax:2697049
3286 98694-98699 Species denotes human Tax:9606
3287 98895-98903 Species denotes SARS-CoV Tax:694009
3288 98910-98918 Species denotes MERS-CoV Tax:1335626
3289 98946-98951 Species denotes human Tax:9606
3290 99004-99014 Species denotes SARS-CoV-2 Tax:2697049
3291 99070-99074 Species denotes mice Tax:10090
3292 99206-99217 Species denotes Ebola virus Tax:1570291
3293 99280-99290 Species denotes SARS-CoV-2 Tax:2697049
3294 99397-99405 Species denotes patients Tax:9606
3295 99711-99715 Species denotes CoVs Tax:11118
3296 99836-99844 Species denotes SARS-CoV Tax:694009
3297 99851-99861 Species denotes SARS-CoV-2 Tax:2697049
3298 98598-98602 Chemical denotes nAbs
3299 99335-99338 Chemical denotes nAb
3300 99572-99575 Chemical denotes nAb
3301 99388-99396 Disease denotes infected MESH:D007239
3323 100345-100347 Gene denotes CP Gene:1356
3324 100171-100173 Gene denotes CP Gene:1356
3325 100744-100746 Gene denotes to Gene:6999
3326 100577-100579 Gene denotes to Gene:6999
3327 100391-100393 Gene denotes to Gene:6999
3328 100094-100096 Gene denotes to Gene:6999
3329 100052-100054 Gene denotes to Gene:6999
3330 100013-100015 Gene denotes to Gene:6999
3331 100097-100105 Species denotes patients Tax:9606
3332 100260-100270 Species denotes SARS-CoV-2 Tax:2697049
3335 100719-100727 Species denotes patients Tax:9606
3336 99910-99921 Species denotes recombinant Tax:575864
3337 100457-100466 Species denotes influenza Tax:11520
3339 99922-99926 Chemical denotes nAbs
3340 100243-100247 Chemical denotes nAbs
3341 100191-100199 Disease denotes infected MESH:D007239
3342 100419-100438 Disease denotes infectious diseases MESH:D003141
3343 100710-100718 Disease denotes COVID-19 MESH:C000657245
3362 103049-103051 Gene denotes CP Gene:1356
3363 102157-102159 Gene denotes CP Gene:1356
3364 102124-102131 Species denotes Patient Tax:9606
3365 102195-102203 Species denotes patients Tax:9606
3366 102315-102323 Species denotes patients Tax:9606
3367 102456-102464 Species denotes patients Tax:9606
3368 102606-102614 Species denotes patients Tax:9606
3369 102661-102669 Species denotes patients Tax:9606
3370 102708-102716 Species denotes patients Tax:9606
3371 102763-102771 Species denotes patients Tax:9606
3372 102783-102791 Species denotes patients Tax:9606
3373 102967-102974 Species denotes patient Tax:9606
3374 102987-102995 Species denotes patients Tax:9606
3375 103095-103103 Species denotes patients Tax:9606
3376 103113-103121 Species denotes patients Tax:9606
3377 102425-102428 Chemical denotes nAb
3378 102620-102635 Disease denotes lymphocytopenia MESH:D008231
3379 102684-102702 Disease denotes SARS-CoV-2 viremia MESH:C000657245
3381 102106-102114 Disease denotes COVID-19 MESH:C000657245
3407 101618-101620 Gene denotes CP Gene:1356
3408 101880-101882 Gene denotes CP Gene:1356
3409 101696-101698 Gene denotes CP Gene:1356
3410 101532-101534 Gene denotes CP Gene:1356
3411 101320-101322 Gene denotes CP Gene:1356
3412 101308-101310 Gene denotes CP Gene:1356
3413 101133-101135 Gene denotes CP Gene:1356
3414 100906-100908 Gene denotes CP Gene:1356
3415 100821-100823 Gene denotes CP Gene:1356
3416 101734-101736 Gene denotes to Gene:6999
3417 101600-101602 Gene denotes to Gene:6999
3418 101535-101537 Gene denotes to Gene:6999
3419 101478-101480 Gene denotes to Gene:6999
3420 101257-101259 Gene denotes to Gene:6999
3421 100920-100928 Species denotes patients Tax:9606
3422 101490-101498 Species denotes patients Tax:9606
3423 101559-101567 Species denotes patients Tax:9606
3424 101664-101672 Species denotes SARS-CoV Tax:694009
3425 101675-101683 Species denotes patients Tax:9606
3426 101737-101745 Species denotes patients Tax:9606
3427 101940-101948 Species denotes patients Tax:9606
3428 101821-101830 Species denotes influenza Tax:11520
3429 100836-100844 Disease denotes COVID-19 MESH:C000657245
3430 101481-101489 Disease denotes COVID-19 MESH:C000657245
3431 101544-101558 Disease denotes critically ill MESH:D016638
3436 103286-103288 Gene denotes CP Gene:1356
3437 103387-103389 Gene denotes to Gene:6999
3438 103355-103357 Gene denotes to Gene:6999
3439 103303-103305 Gene denotes to Gene:6999
3455 104451-104453 Gene denotes to Gene:6999
3456 104236-104238 Gene denotes to Gene:6999
3457 103907-103909 Gene denotes to Gene:6999
3458 103722-103724 Gene denotes to Gene:6999
3459 103691-103693 Gene denotes to Gene:6999
3460 103639-103641 Gene denotes to Gene:6999
3461 103559-103569 Species denotes SARS-CoV-2 Tax:2697049
3462 103918-103924 Species denotes humans Tax:9606
3463 103933-103937 Species denotes CoVs Tax:11118
3464 103977-103985 Species denotes SARS-CoV Tax:694009
3465 103992-104000 Species denotes MERS-CoV Tax:1335626
3466 104239-104249 Species denotes SARS-CoV-2 Tax:2697049
3467 104320-104330 Species denotes SARS-CoV-2 Tax:2697049
3468 103710-103718 Disease denotes COVID-19 MESH:C000657245
3469 103749-103769 Disease denotes SARS-CoV-2 infection MESH:C000657245
3496 105956-105959 Gene denotes CD8 Gene:925
3497 106033-106036 Gene denotes CD4 Gene:12504
3498 104989-104990 Gene denotes S Gene:43740568
3499 105454-105456 Gene denotes to Gene:6999
3500 105305-105307 Gene denotes to Gene:6999
3501 105238-105240 Gene denotes to Gene:6999
3502 105014-105016 Gene denotes to Gene:6999
3503 104639-104641 Gene denotes to Gene:6999
3504 104529-104537 Species denotes SARS-CoV Tax:694009
3505 104837-104845 Species denotes SARS-CoV Tax:694009
3506 104852-104860 Species denotes MERS-CoV Tax:1335626
3507 104952-104962 Species denotes SARS-CoV-2 Tax:2697049
3508 105644-105652 Species denotes SARS-CoV Tax:694009
3509 105981-105985 Species denotes mice Tax:10090
3510 106168-106174 Species denotes people Tax:9606
3511 105106-105110 Chemical denotes nAbs
3512 105257-105261 Chemical denotes nAbs
3513 105431-105435 Chemical denotes nAbs
3514 104658-104671 Disease denotes CoV infection MESH:D018352
3515 104792-104801 Disease denotes infection MESH:D007239
3516 105210-105230 Disease denotes SARS-CoV-1 infection MESH:C000657245
3517 105473-105482 Disease denotes infection MESH:D007239
3518 105782-105791 Disease denotes infection MESH:D007239
3519 105873-105881 Disease denotes memory T MESH:D008569
3520 105929-105938 Disease denotes infection MESH:D007239
3521 106199-106207 Disease denotes COVID-19 MESH:C000657245
3531 107190-107191 Gene denotes M Gene:43740571
3532 107196-107197 Gene denotes N Gene:43740575
3533 107133-107135 Gene denotes to Gene:6999
3534 106705-106707 Gene denotes to Gene:6999
3535 106636-106646 Species denotes SARS-CoV-2 Tax:2697049
3536 106651-106659 Species denotes SARS-CoV Tax:694009
3537 106666-106674 Species denotes MERS-CoV Tax:1335626
3538 107174-107184 Species denotes SARS-CoV-2 Tax:2697049
3539 107286-107294 Species denotes SARS-CoV Tax:694009
3562 109209-109215 Gene denotes b1, b2 Gene:931
3563 110512-110513 Gene denotes M Gene:43740571
3564 110104-110106 Gene denotes to Gene:6999
3565 109927-109929 Gene denotes to Gene:6999
3566 110454-110459 Gene denotes spike Gene:43740568
3567 109451-109459 Species denotes MERS-CoV Tax:1335626
3568 109529-109533 Species denotes nCoV Tax:2697049
3569 109534-109551 Species denotes adenovirus type 5 Tax:28285
3570 109694-109698 Species denotes nCoV Tax:2697049
3571 109702-109712 Species denotes adenovirus Tax:10508
3572 109765-109773 Species denotes MERS-CoV Tax:1335626
3573 110353-110363 Species denotes SARS-CoV-2 Tax:2697049
3574 110403-110413 Species denotes poliovirus Tax:138950
3575 110415-110427 Species denotes rabies virus Tax:11292
3576 110440-110450 Species denotes SARS-CoV-2 Tax:2697049
3577 109355-109357 Disease denotes SE
3578 109838-109846 Disease denotes COVID-19 MESH:C000657245
3579 109875-109883 Disease denotes infected MESH:D007239
3580 109938-109946 Disease denotes COVID-19 MESH:C000657245
3581 110037-110045 Disease denotes COVID-19 MESH:C000657245
3582 110046-110066 Disease denotes aAPCs aAPCs infected MESH:D007239
3583 110115-110123 Disease denotes COVID-19 MESH:C000657245
3590 110614-110625 Species denotes Ebola virus Tax:1570291
3591 110632-110649 Species denotes hepatitis A virus Tax:12092
3592 110656-110676 Species denotes human papillomavirus Tax:10566
3593 110683-110700 Species denotes influenza A virus Tax:11320
3594 110707-110724 Species denotes influenza B virus Tax:11520
3595 110756-110766 Species denotes Zika virus Tax:64320
3603 108051-108053 Gene denotes to Gene:6999
3604 107352-107360 Species denotes SARS-CoV Tax:694009
3605 107367-107375 Species denotes MERS-CoV Tax:1335626
3606 107663-107673 Species denotes SARS-CoV-2 Tax:2697049
3607 108362-108377 Species denotes influenza virus Tax:11308
3608 108554-108569 Species denotes rhesus macaques Tax:9544
3609 107508-107511 Chemical denotes nAb
3640 113344-113346 Gene denotes to Gene:6999
3641 113282-113284 Gene denotes to Gene:6999
3642 113018-113020 Gene denotes to Gene:6999
3643 112942-112944 Gene denotes to Gene:6999
3644 112863-112865 Gene denotes to Gene:6999
3645 112851-112853 Gene denotes to Gene:6999
3646 112767-112769 Gene denotes to Gene:6999
3647 112703-112705 Gene denotes to Gene:6999
3648 112579-112581 Gene denotes to Gene:6999
3649 111844-111846 Gene denotes to Gene:6999
3650 111634-111636 Gene denotes to Gene:6999
3651 111555-111557 Gene denotes to Gene:6999
3652 111539-111541 Gene denotes to Gene:6999
3653 111431-111433 Gene denotes to Gene:6999
3654 110818-110820 Gene denotes to Gene:6999
3655 111019-111027 Species denotes SARS-CoV Tax:694009
3656 111092-111100 Species denotes MERS-CoV Tax:1335626
3657 111163-111173 Species denotes SARS-CoV-2 Tax:2697049
3658 112180-112188 Species denotes patients Tax:9606
3659 113094-113102 Species denotes patients Tax:9606
3660 113167-113179 Species denotes participants Tax:9606
3661 112627-112631 Chemical denotes cGMP
3662 110837-110857 Disease denotes SARS-CoV-2 infection MESH:C000657245
3663 111264-111272 Disease denotes COVID-19 MESH:C000657245
3664 111585-111593 Disease denotes COVID-19 MESH:C000657245
3665 111738-111746 Disease denotes COVID-19 MESH:C000657245
3666 112099-112107 Disease denotes COVID-19 MESH:C000657245
3667 112171-112179 Disease denotes COVID-19 MESH:C000657245
3668 112807-112815 Disease denotes COVID-19 MESH:C000657245
3669 113214-113222 Disease denotes COVID-19 MESH:C000657245
3679 113411-113421 Species denotes SARS-CoV-2 Tax:2697049
3680 113773-113784 Species denotes coronavirus Tax:11118
3681 113805-113813 Species denotes SARS-CoV Tax:694009
3682 113820-113828 Species denotes MERS-CoV Tax:1335626
3683 113976-113984 Species denotes SARS-CoV Tax:694009
3684 113454-113462 Disease denotes COVID-19 MESH:C000657245
3685 113734-113755 Disease denotes SARS-CoV-2 infections MESH:C000657245
3686 113912-113920 Disease denotes COVID-19 MESH:C000657245
3687 113991-114010 Disease denotes MERS-CoV infections MESH:D018352
3706 115352-115354 Gene denotes to Gene:6999
3707 115064-115066 Gene denotes to Gene:6999
3708 114632-114634 Gene denotes to Gene:6999
3709 114068-114070 Gene denotes to Gene:6999
3710 114071-114081 Species denotes SARS-CoV-2 Tax:2697049
3711 114315-114325 Species denotes SARS-CoV-2 Tax:2697049
3712 114400-114413 Species denotes coronaviruses Tax:11118
3713 114545-114555 Species denotes SARS-CoV-2 Tax:2697049
3714 115111-115119 Species denotes patients Tax:9606
3715 115255-115263 Species denotes SARS-CoV Tax:694009
3716 115270-115278 Species denotes MERS-CoV Tax:1335626
3717 115302-115312 Species denotes SARS-CoV-2 Tax:2697049
3718 114122-114144 Disease denotes coronavirus infections MESH:D018352
3719 114256-114265 Disease denotes infection MESH:D007239
3720 114676-114684 Disease denotes COVID-19 MESH:C000657245
3721 114906-114917 Disease denotes lymphopenia MESH:D008231
3722 114939-114958 Disease denotes NK cell dysfunction MESH:D054066
3723 115150-115172 Disease denotes coronavirus infections MESH:D018352
3732 116150-116153 Gene denotes Pia Gene:253260
3733 116227-116231 Gene denotes Mark Gene:4139
3734 116419-116423 Gene denotes Tran Gene:7154
3735 115462-115466 Gene denotes Mark Gene:4139
3736 115818-115844 Disease denotes Maria Kuksin, Julia Kodysh MESH:C537009
3737 116425-116439 Disease denotes Verena van der MESH:C536528
3738 116467-116480 Disease denotes Matthias Wilk MESH:C536617
3739 116587-116601 Disease denotes Jeremiah Faith

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-23 Sentence denotes Immunology of COVID-19:
T2 24-52 Sentence denotes Current State of the Science
T3 54-62 Sentence denotes Abstract
T4 63-359 Sentence denotes The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biological underpinning of COVID19 pathophysiology.
T5 360-577 Sentence denotes In this Review, we summarize the current state of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection and the immunological pathways that likely contribute to disease severity and death.
T6 578-743 Sentence denotes We also discuss the rationale and clinical outcome of current therapeutic strategies as well as prospective clinical trials to prevent or treat SARS-CoV-2 infection.
T7 745-1041 Sentence denotes The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an unprecedented effort from the scientific community to understand the biological underpinning of COVID19 pathophysiology.
T8 1042-1259 Sentence denotes In this Review, we summarize the current state of knowledge of innate and adaptive immune responses elicited by SARS-CoV-2 infection and the immunological pathways that likely contribute to disease severity and death.
T9 1260-1425 Sentence denotes We also discuss the rationale and clinical outcome of current therapeutic strategies as well as prospective clinical trials to prevent or treat SARS-CoV-2 infection.
T10 1427-1436 Sentence denotes Main Text
T11 1438-1450 Sentence denotes Introduction
T12 1451-1737 Sentence denotes The recent emergence and rapid global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting coronavirus disease 2019 (COVID-19) poses an unprecedented health crisis that was declared a pandemic by the World Health Organization (WHO) on March 11, 2020.
T13 1738-1949 Sentence denotes The origin of SARS-CoV-2 was traced to the city of Wuhan in the province of Hubei, China, where a cluster of viral pneumonia cases was first detected, many in connection with the Huanan Seafood Wholesale Market.
T14 1950-2269 Sentence denotes China reported this outbreak to the WHO on December 31, 2019 and soon after identified the causative pathogen as a betacoronavirus with high sequence homology to bat coronaviruses (CoVs) using angiotensin-converting enzyme 2 (ACE2) receptor as the dominant mechanism of cell entry (Lu et al., 2020a, Wan et al., 2020b).
T15 2270-2496 Sentence denotes Following a likely zoonotic spillover, human-to-human transmission events were confirmed with clinical presentations ranging from no symptoms to mild fever, cough, and dyspnea to cytokine storm, respiratory failure, and death.
T16 2497-2727 Sentence denotes SARS-CoV-2 is also closely related to SARS (retrospectively named SARS-CoV-1) and Middle Eastern respiratory syndrome (MERS) CoVs, causing zoonotic epidemic and local outbreaks in 2003 and 2012, respectively (de Wit et al., 2016).
T17 2728-2966 Sentence denotes While SARS-CoV-2 is not as lethal as SARS-CoV-1 or MERS-CoV (Fauci et al., 2020), the considerable spread of the current pandemic has brought tremendous pressure and disastrous consequences for public health and medical systems worldwide.
T18 2967-3191 Sentence denotes The scientific response to the crisis has been extraordinary, with a plethora of COVID-19 studies posted in preprint servers in an attempt to rapidly unravel the pathogenesis of COVID-19 and potential therapeutic strategies.
T19 3192-3600 Sentence denotes In response, trainees and faculty members of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai (PrIISM) have initiated an institutional effort to critically review the preprint literature (Vabret et al., 2020), together with peer-reviewed articles published in traditional journals, and summarize the current state of science on the fast-evolving field of COVID-19 immunology.
T20 3601-3838 Sentence denotes We thematically focus on the innate and adaptive immune responses to SARS-CoV-2 and related CoVs, clinical studies and prognostic laboratory correlates, current therapeutic strategies, prospective clinical trials, and vaccine approaches.
T21 3840-3875 Sentence denotes Innate Immune Sensing of SARS-CoV-2
T22 3876-3985 Sentence denotes Innate immune sensing serves as the first line of antiviral defense and is essential for immunity to viruses.
T23 3986-4087 Sentence denotes To date, our understanding of the specific innate immune response to SARS-CoV-2 is extremely limited.
T24 4088-4311 Sentence denotes However, the virus-host interactions involving SARS-CoV-2 are likely to recapitulate many of those involving other CoVs, given the shared sequence homology among CoVs and the conserved mechanisms of innate immune signaling.
T25 4312-4621 Sentence denotes In the case of RNA viruses such as SARS-CoV-2, these pathways are initiated through the engagement of pattern-recognition receptors (PRRs) by viral single-stranded RNA (ssRNA) and double-stranded RNA (dsRNA) via cytosolic RIG-I like receptors (RLRs) and extracellular and endosomal Toll-like receptors (TLRs).
T26 4622-4708 Sentence denotes Upon PRR activation, downstream signaling cascades trigger the secretion of cytokines.
T27 4709-4951 Sentence denotes Among these, type I/III interferons (IFNs) are considered the most important for antiviral defense, but other cytokines, such as proinflammatory tumor necrosis factor alpha (TNF-α), and interleukin-1 (IL-1), IL-6, and IL-18 are also released.
T28 4952-5053 Sentence denotes Together, they induce antiviral programs in target cells and potentiate the adaptive immune response.
T29 5054-5196 Sentence denotes If present early and properly localized, IFN-I can effectively limit CoV infection (Channappanavar et al., 2016, Channappanavar et al., 2019).
T30 5197-5430 Sentence denotes Early evidence demonstrated that SARS-CoV-2 is sensitive to IFN-I/III pretreatment in vitro, perhaps to a greater degree than SARS-CoV-1 (Blanco-Melo et al., 2020, Lokugamage et al., 2020, Mantlo et al., 2020, Stanifer et al., 2020).
T31 5431-5546 Sentence denotes However, the specific IFN-stimulated genes (ISGs) that mediate these protective effects are still being elucidated.
T32 5547-5722 Sentence denotes Lymphocyte antigen 6 complex locus E (LY6E) has been shown to interfere with SARS-CoV-2 spike (S) protein-mediated membrane fusion (Pfaender et al., 2020, Zhao et al., 2020c).
T33 5723-5988 Sentence denotes Likely, the IFN-induced transmembrane family (IFITM) proteins inhibit SARS-CoV-2 entry, as demonstrated for SARS-CoV-1 (Huang et al., 2011b), although their action in promoting infection has also been described for other CoVs (Zhao et al., 2014, Zhao et al., 2018).
T34 5990-6032 Sentence denotes Evasion of Innate Sensing by Coronaviruses
T35 6033-6176 Sentence denotes As these cytokines represent a major barrier to viral infection, CoVs have evolved several mechanisms to inhibit IFN-I induction and signaling.
T36 6177-6359 Sentence denotes Numerous studies have demonstrated that SARS-CoV-1 suppresses IFN release in vitro and in vivo (Cameron et al., 2012, Minakshi et al., 2009, Siu et al., 2009, Wathelet et al., 2007).
T37 6360-6563 Sentence denotes SARS-CoV-2 likely achieves a similar effect, as suggested by the lack of robust type I/III IFN signatures from infected cell lines, primary bronchial cells, and a ferret model (Blanco-Melo et al., 2020).
T38 6564-6713 Sentence denotes In fact, patients with severe COVID-19 demonstrate remarkably impaired IFN-I signatures as compared to mild or moderate cases (Hadjadj et al., 2020).
T39 6714-6923 Sentence denotes As is often the case, there are multiple mechanisms of evasion for CoVs, with viral factors antagonizing each step of the pathway from PRR sensing and cytokine secretion to IFN signal transduction (Figure 1 ).
T40 6924-7003 Sentence denotes Figure 1 Mechanisms of Host Innate Immune Response and Coronaviruses Antagonism
T41 7004-7178 Sentence denotes Overview of innate immune sensing (left) and interferon signaling (right), annotated with the known mechanisms by which SARS-CoV-1 and MERS-CoV antagonize the pathways (red).
T42 7179-7495 Sentence denotes CoV-mediated antagonism of innate immunity begins with evasion of PRR sensing. ssRNA viruses, like CoVs, form dsRNA intermediates during their replication, which can be detected by TLR3 in the endosome and RIG-I, MDA5, and PKR in the cytosol. ssRNA may also be detected by TLR7 or TLR8 and potentially RIG-I and PKR.
T43 7496-7729 Sentence denotes CoVs are known to avoid PRR activation by either avoiding recognition altogether or antagonizing PRR action (Bouvet et al., 2010, Chen et al., 2009, Deng et al., 2017, Hackbart et al., 2020, Ivanov et al., 2004, Knoops et al., 2008).
T44 7730-7871 Sentence denotes To evade PRRs, dsRNA is first shielded by membrane-bound compartments that form during viral replication of SARS-CoV-1 (Knoops et al., 2008).
T45 7872-8161 Sentence denotes In addition, viral RNA is guanosine-capped and methylated at the 5′ end by CoVs non-structural proteins (NSPs) 10, 13, 14, and 16 (Bouvet et al., 2010, Chen et al., 2009, Ivanov et al., 2004), thereby resembling host mRNA to promote translation, prevent degradation, and evade RLR sensing.
T46 8162-8363 Sentence denotes Finally, CoVs also encode an endoribonuclease, NSP15, that cleaves 5′ polyuridines formed during viral replication, which would otherwise be detected by MDA5 (Deng et al., 2017, Hackbart et al., 2020).
T47 8364-8433 Sentence denotes CoVs have evolved additional strategies to impede activation of PRRs.
T48 8434-8509 Sentence denotes SARS-CoV-1 N-protein prevents TRIM25 activation of RIG-I (Hu et al., 2017).
T49 8510-8708 Sentence denotes Likewise, MERS-CoV NS4a, which itself binds dsRNA, impedes PKR activation (Comar et al., 2019, Rabouw et al., 2016) and inhibits PACT, an activator of RLRs (Niemeyer et al., 2013, Siu et al., 2014).
T50 8709-8810 Sentence denotes Additionally, MERS-CoV NS4b antagonizes RNaseL, another activator of RLRs (Thornbrough et al., 2016).
T51 8811-8850 Sentence denotes The role of other PRRs remains unclear.
T52 8851-9005 Sentence denotes For example, SARS-CoV-1 papain-like protease (PLP) antagonizes STING, suggesting that self-DNA may also represent an important trigger (Sun et al., 2012).
T53 9006-9094 Sentence denotes The extent to which SARS-CoV-2 homologs overlap in these functions is currently unknown.
T54 9095-9352 Sentence denotes Following activation, RLR and TLRs induce signaling cascades, leading to the phosphorylation of transcription factors, such as NF-kB and the interferon-regulatory factor family (IRF), ultimately leading to transcription of IFN and proinflammatory cytokines.
T55 9353-9547 Sentence denotes Although no experimental studies have delineated the precise functions of SARS-CoV-2 proteins, proteomic studies have demonstrated interactions between viral proteins and PRR signaling cascades.
T56 9548-9769 Sentence denotes SARS-CoV-2 ORF9b indirectly interacts with the signaling adaptor MAVS via its association with Tom70 (Gordon et al., 2020), consistent with prior reports that SARS-CoV-1 ORF9b suppresses MAVS signaling (Shi et al., 2014).
T57 9770-9932 Sentence denotes Furthermore, SARS-CoV-2 NSP13 interacts with signaling intermediate TBK1, and NSP15 is associated with RNF41, an activator of TBK1 and IRF3 (Gordon et al., 2020).
T58 9933-10075 Sentence denotes Similarly, SARS-CoV-1 M protein is known to inhibit the TBK1 signaling complex (Siu et al., 2009), as does MERS-CoV ORF4b (Yang et al., 2015).
T59 10076-10245 Sentence denotes Other proteins, including SARS-CoV-1 PLP, N, ORF3b, and ORF6, block IRF3 phosphorylation and nuclear translocation (Devaraj et al., 2007, Kopecky-Bromberg et al., 2007).
T60 10246-10286 Sentence denotes NF-kB is also inhibited by CoV proteins.
T61 10287-10413 Sentence denotes These include SARS-CoV-1 PLP (Frieman et al., 2009) and MERS-CoV ORF4b and ORF5 (Canton et al., 2018, Menachery et al., 2017).
T62 10414-10644 Sentence denotes Finally, SARS-CoV-1 NSP1 (Huang et al., 2011a, Kamitani et al., 2009) and MERS-CoV NSP1 (Lokugamage et al., 2015) initiate general inhibition of host transcription and translation, thus limiting antiviral defenses nonspecifically.
T63 10645-10866 Sentence denotes To prevent signaling downstream of IFN release, CoV proteins inhibit several steps of the signal transduction pathway that bridge the receptor subunits (IFNAR1 and IFNAR2) to the STAT proteins that activate transcription.
T64 10867-11134 Sentence denotes For SARS-CoV-1, these mechanisms include IFNAR1 degradation by ORF3a (Minakshi et al., 2009), decreased STAT1 phosphorylation by NSP1 (Wathelet et al., 2007), and antagonism of STAT1 nuclear translocation by ORF6 (Frieman et al., 2007, Kopecky-Bromberg et al., 2007).
T65 11135-11257 Sentence denotes However, SARS-CoV-2 ORF6 shares only 69% sequence homology with SARS-CoV-1, suggesting this function may not be conserved.
T66 11258-11401 Sentence denotes In support of this notion, SARS-CoV-2 infection fails to limit STAT1 phosphorylation, unlike in SARS-CoV-1 infection (Lokugamage et al., 2020).
T67 11403-11460 Sentence denotes Imbalance between Antiviral and Proinflammatory Responses
T68 11461-11692 Sentence denotes Taken together, the multiplicity of strategies developed by pathogenic CoVs to escape immune sensing, particularly the IFN-I pathway, suggests a critical role played by the dysregulation of IFN-I response in COVID-19 pathogenicity.
T69 11693-11884 Sentence denotes Concordantly, animal models of SARS-CoV-1 and MERS-CoV infection indicate that failure to elicit an early IFN-I response correlates with the severity of disease (Channappanavar et al., 2016).
T70 11885-12082 Sentence denotes Perhaps more importantly, these models demonstrate that timing is key, as IFN is protective early in disease but later becomes pathologic (Channappanavar et al., 2016, Channappanavar et al., 2019).
T71 12083-12204 Sentence denotes Perhaps interferon-induced upregulation of ACE2 in airway epithelia may contribute to this effect (Ziegler et al., 2020).
T72 12205-12341 Sentence denotes Furthermore, while pathogenic CoVs block IFN signaling, they may actively promote other inflammatory pathways contributing to pathology.
T73 12342-12613 Sentence denotes For instance, SARS-CoV-1 ORF3a, ORF8b, and E proteins enhance inflammasome activation (Chen et al., 2019, Nieto-Torres et al., 2015, Shi et al., 2019, Siu et al., 2019), leading to secretion of IL-1β and IL-18, which are likely to contribute to pathological inflammation.
T74 12614-12774 Sentence denotes Similarly, SARS-CoV-2 NSP9 and NSP10 might induce IL-6 and IL-8 production, potentially by inhibition of NKRF, an endogenous NF-kB repressor (Li et al., 2020a).
T75 12775-12967 Sentence denotes Collectively, these proinflammatory processes likely contribute to the “cytokine storm” observed in COVID-19 patients and substantiate a role for targeted immunosuppressive treatment regimens.
T76 12968-13171 Sentence denotes Moving forward, a clear understanding of the delicate balance between antiviral and inflammatory innate immune programs will be essential to developing effective biomarkers and therapeutics for COVID-19.
T77 13173-13186 Sentence denotes Myeloid Cells
T78 13187-13456 Sentence denotes Mucosal immune responses to infectious agents are orchestrated and regulated by myeloid cells with specialized functions, which include conventional dendritic cells (cDCs), monocyte-derived DCs (moDCs), plasmacytoid DCs (pDCs), and macrophages (Guilliams et al., 2013).
T79 13457-13702 Sentence denotes A growing body of evidence points to dysregulated myeloid responses that potentially drive the COVID-19 hallmark syndromes, such as acute respiratory distress syndrome (ARDS), cytokine release syndrome (CRS) and lymphopenia (Mehta et al., 2020).
T80 13704-13740 Sentence denotes Myeloid Characterization in COVID-19
T81 13741-14100 Sentence denotes Flow cytometric analyses of peripheral blood mononuclear cells (PBMCs) from symptomatic COVID-19 patients have shown a significant influx of granulocyte-macrophage colony-stimulating factor (GM-CSF)-producing, activated CD4+ T cells and CD14+HLA-DRlo inflammatory monocytes (IMs) (Giamarellos-Bourboulis et al., 2020, Zhang et al., 2020c, Zhou et al., 2020b).
T82 14101-14545 Sentence denotes This matches single-cell transcriptomic (scRNA-seq) data demonstrating CD14+IL-1β+ monocytic expansion (Guo et al., 2020, Wen et al., 2020), interferon-mitogen-activated protein kinase (MAPK)-driven adaptive immune responses (Huang et al., 2020c), and IL-1β-associated inflammasome signatures (Ong et al., 2020) in peripheral blood of COVID-19 patients, although systemic levels of IL-1β detected are conspicuously low (Del Valle et al., 2020).
T83 14546-14887 Sentence denotes Importantly, these immune signatures track with progression of clinical disease. scRNA-seq studies performed on pulmonary tissues of patients with severe COVID-19 disease have revealed an expansion of IMs and Ficolin-1+ monocyte-derived macrophages at the expense of tissue-resident reparative alveolar macrophages (AMs) (Liao et al., 2020).
T84 14888-15061 Sentence denotes The aforementioned study also observed signatures of IFN signaling and monocyte recruitment that likely contribute to the rapid decline in alveolar patency and promote ARDS.
T85 15062-15307 Sentence denotes Although most of the clinical focus has been on pulmonary damage and mononuclear phagocyte (MNP) dysfunction therein, it is increasingly clear that COVID-19 likely presents systemic challenges in other organ sites, such as the ileum and kidneys.
T86 15308-15434 Sentence denotes Understanding the role of non-pulmonary myeloid cells in tissue-specific pathology associated with COVID-19 will be important.
T87 15436-15503 Sentence denotes Prior Knowledge from SARS-CoV-1, MERS-CoV, and Murine Coronaviruses
T88 15504-15712 Sentence denotes While data on COVID-19 patients continues to rapidly emerge, studies of myeloid cell dysfunction in SARS-CoV-1 and MERS-CoV can provide an important roadmap to understanding COVID-19 pathogenesis (Figure 2 ).
T89 15713-15855 Sentence denotes SARS-CoV-1 infection in mouse models results in an aberrant AM phenotype that limits DC trafficking and T cell activation (Zhao et al., 2009).
T90 15856-16007 Sentence denotes Additionally, YM1+ FIZZ1+ alternative macrophages can increase airway hypersensitivity, thus exacerbating SARS-associated fibrosis (Page et al., 2012).
T91 16008-16319 Sentence denotes Further, as described above, murine SARS-CoV-1 studies have demonstrated that delayed IFN-I signaling and inflammatory monocytes-macrophages promote lung cytokine and chemokine levels, vascular leakage, and impaired antigen-specific T cell responses, culminating in lethal disease (Channappanavar et al., 2016).
T92 16320-16531 Sentence denotes The role played by prominent IFN-producing pDCs in SARS-CoV-2 control or pathogenesis warrants investigation, as they have been shown to be critical in murine CoV (MHV) control (Cervantes-Barragan et al., 2007).
T93 16532-16883 Sentence denotes Longitudinal studies in SARS-CoV-2 models are awaited, but initial phenotypic studies in humanized hACE2 mice have shown the characteristic alveolar interstitial pneumonia, with infiltration of lymphocytes and monocytes and accumulation of macrophages in the alveolar lumen (Bao et al., 2020a), which recapitulates patient findings (Xu et al., 2020c).
T94 16884-17247 Sentence denotes Lastly, non-human primate (NHP) studies and patient data on SARS-CoV-1 have also shown that virus spike-specific immunoglobulin G (IgG) responses can exacerbate acute lung injury due to repolarization of alveolar macrophages into proinflammatory phenotypes and enhanced recruitment of inflammatory monocyte via CCL2 and IL-8 (Clay et al., 2012, Liu et al., 2019).
T95 17248-17362 Sentence denotes However, the extent to which the antibody response contributes to disease pathophysiology remains to be confirmed.
T96 17363-17456 Sentence denotes Figure 2 SARS-CoV-2 Infection Results in Myeloid Cell Activation and Changes NK Cell Function
T97 17457-17550 Sentence denotes Based on data from preliminary COVID-19 studies and earlier studies in related coronaviruses.
T98 17551-17779 Sentence denotes IL-6, IL-1β, and IFN-I/III from infected pulmonary epithelia can induce inflammatory programs in resident (alternate) macrophages while recruiting inflammatory monocytes, as well as granulocytes and lymphocytes from circulation.
T99 17780-17872 Sentence denotes Sustained IL-6 and TNF-ɑ by incoming monocytes can drive several hyperinflammation cascades.
T100 17873-17995 Sentence denotes Inflammatory monocyte-derived macrophages can amplify dysfunctional responses in various ways (listed in top-left corner).
T101 17996-18133 Sentence denotes The systemic CRS- and sHLH-like inflammatory response can induce neutrophilic NETosis and microthrombosis, aggravating COVID-19 severity.
T102 18134-18230 Sentence denotes Other myeloid cells, such as pDCs, are purported to have an IFN-dependent role in viral control.
T103 18231-18294 Sentence denotes Monocyte-derived CXCL9/10/11 might recruit NK cells from blood.
T104 18295-18455 Sentence denotes Preliminary data suggest that the antiviral function of these NK cells might be regulated through crosstalk with SARS-infected cells and inflammatory monocytes.
T105 18456-18503 Sentence denotes Dashed lines indicate pathways to be confirmed.
T106 18504-18766 Sentence denotes Arg1, arginase 1; iNOS, inducible-nitric oxide synthase; Inflamm., inflammatory; Mono., monocytes; Macs, macrophages; Eosino, eosinophils; Neutro, neutrophils; NETosis, neutrophil extracellular trap cell death; SHLH, secondary hemophagocytic lymphohistiocytosis.
T107 18768-18821 Sentence denotes Myeloid Cells Contribution to Pathogenic Inflammation
T108 18822-19010 Sentence denotes The initial mode of viral pathogen-associated signal (PAMP) recognition by innate cells has a major impact on downstream myeloid signaling and cytokine secretion (de Marcken et al., 2019).
T109 19011-19393 Sentence denotes While macrophages are somewhat susceptible to MERS-CoV and SARS-CoV-1 infection (Perlman and Dandekar, 2005, Zhou et al., 2014), data do not suggest that they are infected by SARS-CoV-2, although one study reported ACE2 and SARS-CoV-2 nucleocapsid protein is expressed in lymph nodes and spleen-associated CD169+ macrophages of COVID-19 patients producing IL-6 (Chen et al., 2020h).
T110 19394-19587 Sentence denotes Significantly elevated systemic levels of proinflammatory cytokine IL-6 have been reported in several COVID-19 patient cohorts and shown to correlate with disease severity (Mehta et al., 2020).
T111 19588-19735 Sentence denotes Increased IL-6 can also be associated with higher levels of IL-2, IL-7, IFN-ɣ, and GM-CSF, as seen in secondary hemophagocytic lymphohistiocytosis.
T112 19736-20016 Sentence denotes In response to viral infections, MNPs drive IL and IFN-I and IFN-III production resulting in inflammasome activation, induction of pathogenic Th1 and Th17 cell responses, recruitment of effector immune cells, and CRS pathology (Prokunina-Olsson et al., 2020, Tanaka et al., 2016).
T113 20017-20247 Sentence denotes Independently, in vitro studies have demonstrated SARS-CoV-1 infection can induce intracellular stress pathways, resulting in NLRP3-dependent inflammasome activation and macrophage pyroptosis (Chen et al., 2019, Shi et al., 2019).
T114 20248-20460 Sentence denotes Functional studies are required to implicate these myeloid inflammasome pathways in COVID-19 lung pathology and to assess other immunogenic pathways such as RIPK1/3-dependent necroptosis (Nailwal and Chan, 2019).
T115 20461-20625 Sentence denotes In conclusion, the strength and duration of myeloid ISG)signaling potentially dictate COVID-19 disease severity, but rigorous studies are warranted to confirm this.
T116 20626-20831 Sentence denotes Lastly, more work is needed to ascertain the mechanistic role played by lung-resident and recruited granulocytes in SARS-CoV-2 control and pathogenesis (Camp and Jonsson, 2017, Flores-Torres et al., 2019).
T117 20832-21074 Sentence denotes In contrast to their early protective role, neutrophil NETosis and macrophage crosstalk can drive later-stage inflammatory cascades (Barnes et al., 2020), underscoring the overall pathogenic nature of damage-sensing host responses (Figure 2).
T118 21075-21314 Sentence denotes Collectively, the current knowledge of CoVs and SARS-CoV-2 infection, in particular, points to an inadvertent collusion involving myeloid cells in COVID-19 pathogenesis, despite their critical role in early sensing and antiviral responses.
T119 21316-21337 Sentence denotes Innate Lymphoid Cells
T120 21338-21504 Sentence denotes Innate lymphoid cells (ILCs) are innate immune effector cells that lack the expression of rearranged antigen receptors (T cell receptor [TCR], B cell receptor [BCR]).
T121 21505-21685 Sentence denotes The ILC family is divided into two main groups: the cytotoxic natural killer (NK) cells and the non-cytotoxic helper ILCs, which include ILC1, ILC2, and ILC3 (Vivier et al., 2018).
T122 21686-21840 Sentence denotes Conventional NK cells include CD56brightCD16− NK cells and CD56dimCD16+ cells, which are specialized in cytokine production or cytotoxicity, respectively.
T123 21842-21909 Sentence denotes NK Cells Are Decreased in the Peripheral Blood of COVID-19 patients
T124 21910-22142 Sentence denotes Multiple studies have reported reduced numbers of NK cells in the peripheral blood of COVID-19 patients, which is associated with severity of the disease (Song et al., 2020, Wang et al., 2020f, Yu et al., 2020, Zheng et al., 2020b).
T125 22143-22311 Sentence denotes A recent scRNA-seq analysis revealed a transcriptomic signature for NK cells that was equally represented in lungs from patients and healthy donors (Liao et al., 2020).
T126 22312-22513 Sentence denotes The majority of lung NK cells are non-resident (Gasteiger et al., 2015, Marquardt et al., 2017), and CXCR3 has been shown to mediate NK cell infiltration upon influenza infection (Carlin et al., 2018).
T127 22514-22728 Sentence denotes In vitro, CXCR3 ligands (CXCL9-11) are increased in SARS-CoV-2-infected human lung tissue (Chu et al., 2020), and CXCR3-ligand-producing monocytes are expanded in the lungs of COVID-19 patients (Liao et al., 2020).
T128 22729-22874 Sentence denotes This suggests that the CXCR3 pathway might facilitate NK cell recruitment from the peripheral blood to the lungs in COVID-19 patients (Figure 2).
T129 22876-22925 Sentence denotes NK Cell Activation Pathways in Antiviral Immunity
T130 22926-23012 Sentence denotes NK cells express inhibitory and activating receptors that regulate their cytotoxicity.
T131 23013-23327 Sentence denotes They are therefore able to induce the lysis of virus-infected cells that upregulate virus-derived proteins, as well as stress-inducible ligands, which are then recognized by NK-cell-activating receptors, such as NKp46 (Cerwenka and Lanier, 2001, Draghi et al., 2007, Duev-Cohen et al., 2016, Glasner et al., 2012).
T132 23328-23524 Sentence denotes Future studies should investigate the expression of NK receptor ligands on SARS-CoV-2-infected cells in order to better understand the mechanisms underlying NK cell activation in COVID-19 disease.
T133 23525-23832 Sentence denotes Further, secretion of IgG1 and IgG3 antibodies during SARS-CoV-2 infection (Amanat et al., 2020) may induce CD56dim CD16+ NK cell activation through Fc receptor recognition of antibodies either bound to surface antigens expressed on infected cells or to extracellular virions as immune complexes (Figure 2).
T134 23833-24045 Sentence denotes This interaction might trigger both cytokine production by NK cells and lysis of infected cells through antibody-mediated cellular cytotoxicity (ADCC), as shown in influenza infection (Von Holle and Moody, 2019).
T135 24046-24285 Sentence denotes Emerging data highlight the capacity for NK-mediated ADCC in response to naturally isolated SARS-CoV-1 anti-S IgG that crossreacts with SARS-CoV-2 S glycoprotein when transfected into Chinese hamster ovary (CHO) cells (Pinto et al., 2020).
T136 24286-24450 Sentence denotes These findings suggest that triggering NK cell activation may not only contribute to the resolution of infection, but also contribute to the cytokine storm in ARDS.
T137 24452-24506 Sentence denotes Impairment of NK Cell Function in SARS-CoV-2 Infection
T138 24507-24795 Sentence denotes Ex vivo NK cells from peripheral blood of COVID-19 patients have reduced intracellular expression of CD107a, Ksp37, granzyme B, and granulysin, suggesting an impaired cytotoxicity, as well as an impaired production of chemokines, IFN-ɣ, and TNF-α (Wilk et al., 2020, Zheng et al., 2020b).
T139 24796-24861 Sentence denotes Several pathways may contribute to the dysregulation of NK cells.
T140 24862-25104 Sentence denotes While influenza virus infects NK cells and induces apoptosis (Mao et al., 2009), lung NK cells do not express the entry receptor for SARS-CoV-2, ACE2, and are therefore unlikely to be directly infected by SARS-CoV-2 (Travaglini et al., 2020).
T141 25105-25422 Sentence denotes The majority of NK cells found in human lung display a mature CD16+KIR+CD56dim phenotype and are able to induce cell cytotoxicity in response to loss of human leukocyte antigen (HLA) class I or through Fc receptor signaling, although to a lower extent than their peripheral blood counterpart (Marquardt et al., 2017).
T142 25423-25637 Sentence denotes Killer-immunoglobulin receptors (KIRs) are acquired during NK cell development alongside CD16 (FcRγIIIA) and are essential for NK cell licensing and subsequent capacity for cytolytic function (Sivori et al., 2019).
T143 25638-25816 Sentence denotes Frequencies of NK cells expressing CD16 and/or KIRs are decreased in the blood following SARS-CoV-2 and SARS-CoV-1 infection, respectively (Xia et al., 2004, Wang et al., 2020d).
T144 25817-26024 Sentence denotes Collectively, the data suggest either an impaired maturation of the NK compartment or migration of the mature, circulating NK cells into the lungs or other peripheral tissues of SARS-CoV-2-infected patients.
T145 26025-26139 Sentence denotes The immune checkpoint NKG2A is increased on NK cells and CD8 T cells from COVID-19 patients (Zheng et al., 2020b).
T146 26140-26365 Sentence denotes NKG2A inhibits cell cytotoxicity by binding the non-classical HLA-E molecule (Braud et al., 1998, Brooks et al., 1997), and this interaction is strongly correlated with poor control of HIV-1 infection (Ramsuran et al., 2018).
T147 26366-26518 Sentence denotes Genes encoding the inhibitory receptors LAG3 and TIM3 are also upregulated in NK cells from COVID-19 patients (Wilk et al., 2020, Hadjadj et al., 2020).
T148 26519-26599 Sentence denotes Thus, increased immune checkpoints on NK cells might contribute to viral escape.
T149 26600-26795 Sentence denotes Additionally, COVID-19 patients have higher plasma concentrations of IL-6 (Huang et al., 2020b), which significantly correlate with lower NK cell numbers (Wang et al., 2020d, Wang et al., 2020f).
T150 26796-27064 Sentence denotes In vitro stimulation by IL-6 and soluble IL-6 receptor has previously revealed impaired cytolytic functions (perforin and granzyme B production) by healthy donor NK cells, which can be restored following addition of tocilizumab (IL-6R blockade) (Cifaldi et al., 2015).
T151 27065-27322 Sentence denotes TNF-α is also upregulated in the plasma of COVID-19 patients (Huang et al., 2020b), and ligand-receptor interaction analysis of peripheral blood scRNA-seq data suggests that monocyte-secreted TNF-α might bind to its receptors on NK cells (Guo et al., 2020).
T152 27323-27546 Sentence denotes TNF-α is known to contribute to NK cell differentiation (Lee et al., 2009), which includes downregulation of NKp46 (Ivagnès et al., 2017), though no effect of TNF-α or IL-6 on NK cell-mediated ADCC has been reported so far.
T153 27547-27804 Sentence denotes Collectively, these data suggest that crosstalk with monocytes might impair NK cell recognition and killing of SARS-CoV-2-infected cells, and antibodies targeting IL-6 and TNF-signaling may benefit enhanced NK cell functions in COVID-19 patients (Figure 2).
T154 27806-27855 Sentence denotes Relevance for Helper ILCs in SARS-CoV-2 Infection
T155 27856-27945 Sentence denotes No studies, to date, have reported ILC1, ILC2, or ILC3 functions in SARS-CoV-2 infection.
T156 27946-28038 Sentence denotes All three subsets are present in healthy lung (De Grove et al., 2016, Yudanin et al., 2019).
T157 28039-28249 Sentence denotes ILC2s are essential for the improvement of lung function following influenza infection in mice through amphiregulin-mediated restoration of the airway epithelium and oxygen saturation (Monticelli et al., 2011).
T158 28250-28410 Sentence denotes However, ILC2s also produce IL-13, contributing to the recruitment of macrophages to the lung and influenza-induced airway hyperreactivity (Chang et al., 2011).
T159 28411-28581 Sentence denotes Indeed, ILCs are involved in the polarization of alveolar macrophages, either toward a M1-like phenotype (ILC1 and ILC3) or a M2-like phenotype (ILC2) (Kim et al., 2019).
T160 28582-28807 Sentence denotes Given the increased IL-13 concentrations (Huang et al., 2020b) and the dysregulation of the macrophage compartment observed in COVID-19 patients, the role played by ILCs in SARS-CoV-2 infection warrants further investigation.
T161 28809-28825 Sentence denotes T Cell Responses
T162 28826-29054 Sentence denotes T cells play a fundamental role in viral infections: CD4 T cells provide B cell help for antibody production and orchestrate the response of other immune cells, whereas CD8 T cells kill infected cells to reduce the viral burden.
T163 29055-29124 Sentence denotes However, dysregulated T cell responses can result in immunopathology.
T164 29125-29465 Sentence denotes To better understand the role of T cell responses in SARS-CoV-2 infection, the pursuit of two major questions is imperative: (1) what is the contribution of T cells to initial virus control and tissue damage in the context of COVID-19, and (2) how do memory T cells established thereafter contribute to protective immunity upon reinfection?
T165 29466-29513 Sentence denotes Some tentative answers are beginning to emerge.
T166 29515-29581 Sentence denotes Overall Reduction of CD4 and CD8 T Cell Counts in Peripheral Blood
T167 29582-29935 Sentence denotes Similar to earlier observations about SARS-CoV-1 infection (He et al., 2005), several current reports emphasize the occurrence of lymphopenia with drastically reduced numbers of both CD4 and CD8 T cells in moderate and severe COVID-19 cases (Figure 3 ) (Chen et al., 2020c, Nie et al., 2020b, Wang et al., 2020d, Zeng et al., 2020, Zheng et al., 2020b).
T168 29936-30299 Sentence denotes The extent of lymphopenia—most striking for CD8 T cells in patients admitted to the intensive care unit (ICU)—seemingly correlates with COVID-19-associated disease severity and mortality (Chen et al., 2020c, Diao et al., 2020, Liu et al., 2020b, Liu et al., 2020c, Tan et al., 2020a, Wang et al., 2020d, Wang et al., 2020f, Zeng et al., 2020, Zhou et al., 2020c).
T169 30300-30446 Sentence denotes Patients with mild symptoms, however, typically present with normal or slightly higher T cell counts (Liu et al., 2020a, Thevarajan et al., 2020).
T170 30447-30698 Sentence denotes The cause of peripheral T cell loss in moderate to severe COVID-19, though a phenomenon also observed in other viral infections, remains elusive, and direct viral infection of T cells, in contrast to MERS-CoV (Chu et al., 2016), has not been reported.
T171 30699-30757 Sentence denotes Figure 3 Working Model for T Cell Responses to SARS-CoV-2:
T172 30758-30818 Sentence denotes Changes in Peripheral Blood T Cell Frequencies and Phenotype
T173 30819-30943 Sentence denotes A decrease in peripheral blood T cells associated with disease severity and inflammation is now well documented in COVID-19.
T174 30944-31228 Sentence denotes Several studies report increased numbers of activated CD4 and CD8 T cells, which display a trend toward an exhausted phenotype in persistent COVID-19, based on continuous and upregulated expression of inhibitory markers as well as potential reduced polyfunctionality and cytotoxicity.
T175 31229-31332 Sentence denotes In severe disease, production of specific inflammatory cytokines by CD4 T cells has also been reported.
T176 31333-31490 Sentence denotes This working model needs to be confirmed and expanded on in future studies to assess virus-specific T cell responses both in peripheral blood and in tissues.
T177 31491-31653 Sentence denotes In addition, larger and more defined patient cohorts with longitudinal data are required to define the relationship between disease severity and T cell phenotype.
T178 31654-31820 Sentence denotes IL, interleukin; IFN, interferon; TNF, tumor necrosis factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; GzmA/B, granzyme A/granzyme B; Prf1, perforin.
T179 31821-31961 Sentence denotes Several mechanisms likely contribute to the reduced number of T cells in the blood, including effects from the inflammatory cytokine milieu.
T180 31962-32312 Sentence denotes Indeed, lymphopenia seems to correlate with serum IL-6, IL-10, and TNF-α (Diao et al., 2020, Wan et al., 2020a), while convalescent patients were found to have restored bulk T cell frequencies paired with overall lower proinflammatory cytokine levels (Chen et al., 2020f, Diao et al., 2020, Liu et al., 2020a, Liu et al., 2020b, Zheng et al., 2020b).
T181 32313-32505 Sentence denotes Cytokines such as IFN-I and TNF-α may inhibit T cell recirculation in blood by promoting retention in lymphoid organs and attachment to endothelium (Kamphuis et al., 2006, Shiow et al., 2006).
T182 32506-32772 Sentence denotes However, in an autopsy study examining the spleens and hilar lymph nodes of six patients who succumbed to COVID-19, Chen et al. observed extensive cell death of lymphocytes and suggested potential roles for IL-6 as well as Fas-FasL interactions (Chen et al., 2020h).
T183 32773-32943 Sentence denotes In support of this hypothesis, the IL-6 receptor antagonist tocilizumab was found to increase the number of circulating lymphocytes (Giamarellos-Bourboulis et al., 2020).
T184 32944-33219 Sentence denotes T cell recruitment to sites of infection may also reduce their presence in the peripheral blood compartment. scRNA-seq analysis of bronchoalveolar lavage (BAL) fluid of COVID-19 patients revealed an increase in CD8 T cell infiltrate with clonal expansion (Liao et al., 2020).
T185 33220-33393 Sentence denotes Likewise, post-mortem examination of a patient who succumbed to ARDS following SARS-CoV-2 infection showed extensive lymphocyte infiltration in the lungs (Xu et al., 2020c).
T186 33394-33538 Sentence denotes However, another study that examined post-mortem biopsies from four COVID-19 patients only found neutrophilic infiltration (Tian et al., 2020a).
T187 33539-33675 Sentence denotes Further studies are therefore needed to better determine the cause and impact of the commonly observed lymphopenia in COVID-19 patients.
T188 33677-33716 Sentence denotes Induction of Antiviral T Cell Responses
T189 33717-33859 Sentence denotes Available information about SARS-CoV-1-specific T cell immunity may serve as an orientation for further understanding of SARS-CoV-2 infection.
T190 33860-34057 Sentence denotes Immunogenic T cell epitopes are distributed across several SARS-CoV-1 proteins (S, N, and M, as well as ORF3), although CD4 T cell responses were more restricted to the S protein (Li et al., 2008).
T191 34058-34332 Sentence denotes In SARS-CoV-1 survivors, the magnitude and frequency of specific CD8 memory T cells exceeded that of CD4 memory T cells, and virus-specific T cells persisted for at least 6–11 years, suggesting that T cells may confer long-term immunity (Ng et al., 2016, Tang et al., 2011).
T192 34333-34599 Sentence denotes Limited data from viremic SARS patients further indicated that virus-specific CD4 T cell populations might be associated with a more severe disease course, since lethal outcomes correlated with elevated Th2 cell (IL-4, IL-5, IL-10) serum cytokines (Li et al., 2008).
T193 34600-34728 Sentence denotes However, the quality of CD4 T cell responses needs to be further characterized to understand associations with disease severity.
T194 34729-34818 Sentence denotes Few studies have thus far characterized specific T cell immunity in SARS-CoV-2 infection.
T195 34819-35217 Sentence denotes In 12 patients recovering from mild COVID-19, robust T cell responses specific for viral N, M, and S proteins were detected by IFN-γ ELISPOT, weakly correlated with neutralizing antibody concentrations (similar to convalescent SARS-CoV-1 patients; Li et al., 2008), and subsequently contracted with only N-specific T cells detectable in about one-third of the cases post recovery (Ni et al., 2020).
T196 35218-35393 Sentence denotes In a second study, PBMCs from COVID-19 patients with moderate to severe ARDS were analyzed by flow cytometry approximately 2 weeks after ICU admission (Weiskopf et al., 2020).
T197 35394-35736 Sentence denotes Both virus-specific CD4 and CD8 T cells were detected in all patients at average frequencies of 1.4% and 1.3%, respectively, and very limited phenotyping according to CD45RA and CCR7 expression status characterized these cells predominantly as either CD4 Tcm (central memory) or CD8 Tem (effector memory) and Temra (effector memory RA) cells.
T198 35737-36199 Sentence denotes This study is notable for the use of large complementary peptide pools comprising 1,095 SARS-Cov-2 epitopes (overlapping 15-mers for S protein as well as computationally predicted HLA-I- and -II-restricted epitopes for all other viral proteins) as antigen-specific stimuli that revealed a preferential specificity of both CD4 and CD8 T cells for S protein epitopes, with the former population modestly increasing over ∼10–30 days after initial onset of symptoms.
T199 36200-36452 Sentence denotes A caveat, however, pertains to the identification of specific T cells by induced CD69 and CD137 co-expression, since upregulation of CD137 by CD4 T cells, in contrast to CD154, may preferentially capture regulatory T cells (Treg) (Bacher et al., 2016).
T200 36453-36634 Sentence denotes Further analyses of S protein-specific T cells by ELISA demonstrated robust induction of IFN-γ, TNF-α, and IL-2 concomitant with lower levels of IL-5, IL-13, IL-9, IL-10, and IL-22.
T201 36635-36861 Sentence denotes A third report focused on S-specific CD4 T cell responses in 18 patients with mild, severe, or critical COVID-19 using overlapping peptide pools and induced CD154 and CD137 co-expression as a readout for antiviral CD4 T cells.
T202 36862-37026 Sentence denotes Such cells were present in 83% of cases and presented with enhanced CD38, HLA-DR, and Ki-67 expression indicative of recent in vivo activation (Braun et al., 2020).
T203 37027-37161 Sentence denotes Of note, the authors also detected low frequencies of S-reactive CD4 T cells in 34% of SARS-CoV-2 seronegative healthy control donors.
T204 37162-37582 Sentence denotes However, these CD4 T cells lacked phenotypic markers of activation and were specific for C-terminal S protein epitopes that are highly similar to endemic human CoVs, suggesting that crossreactive CD4 memory T cells in some populations (e.g., children and younger patients that experience a higher incidence of hCoV infections) may be recruited into an amplified primary SARS-CoV-2-specific response (Braun et al., 2020).
T205 37583-37706 Sentence denotes Similarly, endemic CoV-specific CD4 T cells were previously shown to recognize SARS-CoV1 determinants (Gioia et al., 2005).
T206 37707-37827 Sentence denotes How previous infections with endemic CoV may affect immune responses to SARS-CoV-2 will need to be further investigated.
T207 37828-38154 Sentence denotes Finally, in general accordance with the above findings on the induction of SARS-CoV-2-specific T cells, using TCR sequencing (TCR-seq), Huang et al. and Liao et al. reported greater TCR clonality of peripheral blood (Huang et al., 2020c) as well as BAL T cells (Liao et al., 2020) in patients with mild versus severe COVID-19.
T208 38155-38411 Sentence denotes Moving forward, a comprehensive identification of immunogenic SARS-CoV-2 epitopes recognized by T cells (Campbell et al., 2020), as well as further studies on convalescent patients who recovered from mild and severe disease, will be particularly important.
T209 38413-38462 Sentence denotes T Cell Contribution to COVID-19 Hyperinflammation
T210 38463-38681 Sentence denotes While the induction of robust T cell immunity is likely essential for efficient virus control, dysregulated T cell responses may cause immunopathology and contribute to disease severity in COVID-19 patients (Figure 3).
T211 38682-38935 Sentence denotes This is suggested in a study by Zhou et al., which reported a significantly increased PBMC frequency of polyclonal GM-CSF+ CD4 T cells capable of prodigious ex vivo IL-6 and IFN-γ production only in critically ill COVID-19 patients (Zhou et al., 2020c).
T212 38936-39224 Sentence denotes Of note, GM-CSF+ CD4 T cells have been previously implicated in inflammatory autoimmune diseases, such as multiple sclerosis or juvenile rheumatoid arthritis, and high levels of circulating GM-CSF+ CD4 T cells were found to be associated with poor outcomes in sepsis (Huang et al., 2019).
T213 39225-39358 Sentence denotes Additionally, two studies observed reduced frequencies of Treg cells in severe COVID-19 cases (Chen et al., 2020c, Qin et al., 2020).
T214 39359-39547 Sentence denotes Since Treg cells have been shown to help resolve ARDS inflammation in mouse models (Walter et al., 2018), a loss of Tregs might facilitate the development of COVID-19 lung immunopathology.
T215 39548-39805 Sentence denotes Similarly, a reduction of γδ-T cells, a subset of T cells with apparent protective antiviral function in influenza pneumonia (Dong et al., 2018, Zheng et al., 2013), has been reported in severely sick COVID-19 patients (Guo et al., 2020, Lei et al., 2020b).
T216 39807-39859 Sentence denotes Phenotype and Function of T Cell Subsets in COVID-19
T217 39860-39973 Sentence denotes Currently, little is known about specific phenotypical and/or functional T cell changes associated with COVID-19.
T218 39974-40316 Sentence denotes In the majority of preprints and peer-reviewed studies, there are reports of increased presence of activated T cells (Figure 3) characterized by expression of HLA-DR, CD38, CD69, CD25, CD44, and Ki-67 (Braun et al., 2020, Ni et al., 2020, Guo et al., 2020, Liao et al., 2020, Thevarajan et al., 2020, Yang et al., 2020a, Zheng et al., 2020a).
T219 40317-40587 Sentence denotes Generally, independent of COVID-19 disease severity, CD8 T cells seem to be more activated than CD4 T cells (Qin et al., 2020, Thevarajan et al., 2020, Yang et al., 2020a), a finding that echoes stronger CD8 than CD4 T cell responses during SARS-CoV-1 (Li et al., 2008).
T220 40588-40763 Sentence denotes Furthermore, in a case study of 10 COVID-19 patients, Diao et al. showed that levels of PD-1 increased from prodromal to symptomatic stages of the disease (Diao et al., 2020).
T221 40764-40984 Sentence denotes PD-1 expression is commonly associated with T cell exhaustion, but it is important to emphasize that PD-1 is primarily induced by TCR signaling; it is thus also expressed by activated effector T cells (Ahn et al., 2018).
T222 40985-41210 Sentence denotes In addition, several studies reported higher expression of various co-stimulatory and inhibitory molecules such as OX-40 and CD137 (Zhou et al., 2020c), CTLA-4 and TIGIT (Zheng et al., 2020a), and NKG2a (Zheng et al., 2020b).
T223 41211-41380 Sentence denotes Reduced numbers of CD28+ CD8 T cells (Qin et al., 2020) as well as larger frequencies of PD-1+ TIM3+ CD8 T cells in ICU patients were also reported (Zhou et al., 2020c).
T224 41381-41579 Sentence denotes Expression of most of these markers was found to be higher in CD8 than in CD4 T cells, and levels tended to increase in severe versus non-severe cases, which may be due to differences in viral load.
T225 41580-41957 Sentence denotes Cellular functionality was shown to be impaired in CD4 and CD8 T cells of critically ill patients, with reduced frequencies of polyfunctional T cells (producing more than one cytokine) as well as generally lower IFN-γ and TNF-α production following restimulation with phorbol myristate acetate (PMA) and ionomycin (Chen et al., 2020c, Zheng et al., 2020a, Zheng et al., 2020b).
T226 41958-42156 Sentence denotes Similarly, Zheng et al. reported that CD8 T cells in severe COVID-19 appear less cytotoxic and effector-like with reduced CD107a degranulation and granzyme B (GzmB) production (Zheng et al., 2020b).
T227 42157-42300 Sentence denotes In contrast, a different study found that both GzmB and perforin were increased in CD8 T cells of severely sick patients (Zheng et al., 2020a).
T228 42301-42658 Sentence denotes In accordance with the latter observation, when compared to a moderate disease group, convalescent patients with resolved severe SARS-CoV-1 infection had significantly higher frequencies of polyfunctional T cells, with CD4 T cells producing more IFN-γ, TNF-α, and IL-2 and CD8 T cells producing more IFN-γ, TNF-α, and CD107a, respectively (Li et al., 2008).
T229 42659-42850 Sentence denotes However, given the vigorous dynamics of acute T cell responses and potential differences in sample timing throughout disease course, these observations are not necessarily mutually exclusive.
T230 42851-43117 Sentence denotes Accordingly, RNA sequencing (RNA-seq) data by Liao et al. showed that CD8 T cells in the BAL fluid of severe COVID-19 patients express cytotoxic genes such as GZMA, GZMB, and GZMK at higher levels, while KLRC1 and XCL1 are enriched in mild cases (Liao et al., 2020).
T231 43118-43363 Sentence denotes In summary, T cells in severe COVID-19 seem to be more activated and may exhibit a trend toward exhaustion based on continuous expression of inhibitory markers such as PD-1 and TIM-3 as well as overall reduced polyfunctionality and cytotoxicity.
T232 43364-43667 Sentence denotes Conversely, recovering patients were shown to have an increase in follicular helper CD4 T cells (TFH) as well as decreasing levels of inhibitory markers along with enhanced levels of effector molecules such as Gzm A, GzmB, and perforin (Thevarajan et al., 2020, Yang et al., 2020a, Zheng et al., 2020b).
T233 43668-43902 Sentence denotes Collectively, these studies provide a first glimpse into T cell dynamics in acute SARS-CoV-2 infection, but any conclusions have to be tempered at this stage on account of significant limitations in many of the current investigations.
T234 43904-43920 Sentence denotes B Cell Responses
T235 43922-43957 Sentence denotes Acute B Cell and Antibody Responses
T236 43958-44107 Sentence denotes The humoral immune response is critical for the clearance of cytopathic viruses and is a major part of the memory response that prevents reinfection.
T237 44108-44315 Sentence denotes SARS-CoV-2 elicits a robust B cell response, as evidenced by the rapid and near-universal detection of virus-specific IgM, IgG and IgA, and neutralizing IgG antibodies (nAbs) in the days following infection.
T238 44316-44424 Sentence denotes The kinetics of the antibody response to SARS-CoV-2 are now reasonably well described (Huang et al., 2020a).
T239 44425-44794 Sentence denotes Similar to SARS-CoV-1 infection (Hsueh et al., 2004), seroconversion occurs in most COVID-19 patients between 7 and 14 days after the onset of symptoms, and antibody titers persist in the weeks following virus clearance (Figure 4 ) (Haveri et al., 2020, Lou et al., 2020, Okba et al., 2020, Tan et al., 2020b, Wölfel et al., 2020, Wu et al., 2020b, Zhao et al., 2020a).
T240 44795-44958 Sentence denotes Antibodies binding the SARS-CoV-2 internal N protein and the external S glycoprotein are commonly detected (Amanat et al., 2020, Ju et al., 2020, To et al., 2020).
T241 44959-45197 Sentence denotes The receptor binding domain (RBD) of the S protein is highly immunogenic, and antibodies binding this domain can be potently neutralizing, blocking virus interactions with the host entry receptor, ACE2 (Ju et al., 2020, Wu et al., 2020b).
T242 45198-45302 Sentence denotes Anti-RBD nAbs are detected in most tested patients (Ju et al., 2020, To et al., 2020, Wu et al., 2020b).
T243 45303-45500 Sentence denotes Although crossreactivity to SARS-CoV-1 S and N proteins and to MERS-CoV S protein was detected in plasma from COVID-19 patients, no crossreactivity was found to the RBD from SARS-CoV-1 or MERS-CoV.
T244 45501-45604 Sentence denotes In addition, plasma from COVID-19 patients did not neutralize SARS-CoV-1 or MERS-CoV (Ju et al., 2020).
T245 45605-45654 Sentence denotes Figure 4 Antibody-Mediated Immunity in SARS-CoV-2
T246 45655-45756 Sentence denotes Virus-specific IgM and IgG are detectable in serum between 7 and 14 days after the onset of symptoms.
T247 45757-45825 Sentence denotes Viral RNA is inversely correlated with neutralizing antibody titers.
T248 45826-45974 Sentence denotes Higher titers have been observed in critically ill patients, but it is unknown whether antibody responses somehow contribute to pulmonary pathology.
T249 45975-46163 Sentence denotes The SARS-CoV-1 humoral response is relatively short lived, and memory B cells may disappear altogether, suggesting that immunity with SARS-CoV-2 may wane 1–2 years after primary infection.
T250 46164-46333 Sentence denotes RBD-specific CD19+IgG+ memory B cells were single-cell sorted from a cohort of eight COVID-19 donors between days 9 and 28 after the onset of symptoms (Ju et al., 2020).
T251 46334-46430 Sentence denotes From their antibody gene sequences, 209 SARS-CoV-2-specific monoclonal antibodies were produced.
T252 46431-46662 Sentence denotes The monoclonal antibodies had a diverse repertoire, relatively low or no somatic mutations, and variable binding reactivity, with dissociation constants reaching 10−8 to 10−9, similar to antibodies isolated during acute infections.
T253 46663-46833 Sentence denotes Two potent neutralizing SARS-CoV-2 RBD-specific monoclonal antibodies were characterized that did not crossreact with the RBD of SARS-CoV-1 or MERS-CoV (Ju et al., 2020).
T254 46834-46982 Sentence denotes Together, these results demonstrate that antibody mediated neutralization is virus specific and likely driven by binding of epitopes within the RBD.
T255 46984-46998 Sentence denotes B Cell Memory:
T256 46999-47023 Sentence denotes Development and Lifespan
T257 47024-47166 Sentence denotes The B cell response to a virus serves not only to protect from the initial challenge, but also to offer extended immunity against reinfection.
T258 47167-47332 Sentence denotes Following resolution of an infection, plasma cells formed during the acute and convalescent phases continue to secrete antibodies, giving rise to serological memory.
T259 47333-47441 Sentence denotes Memory B cells that are also formed during the primary infection constitute the second arm of B cell memory.
T260 47442-47539 Sentence denotes Memory B cells can quickly respond to a reinfection by generating new high-affinity plasma cells.
T261 47540-47641 Sentence denotes Long-term protection is achieved through the induction of long-lived plasma cells and memory B cells.
T262 47642-47737 Sentence denotes There is great interest in understanding the lifespan of B cell memory responses to SARS-CoV-2.
T263 47738-47891 Sentence denotes Protection from reinfection has direct medical and social consequences as the world works to develop vaccination strategies and resume normal activities.
T264 47892-48133 Sentence denotes In COVID-19 patients, evidence of near-universal seroconversion and the lack of substantial descriptions of reinfection point to a robust antibody response, which, along with the T cell memory response, would offer protection to reinfection.
T265 48134-48492 Sentence denotes Indeed, a case study of a single patient described induction of CD38HiCD27Hi antibody-secreting cells (ASCs), concomitant with an increase in circulating follicular T helper cells (Tfh) cells (Thevarajan et al., 2020), and a scRNA-seq study of PBMCs from critically ill and recently recovered individuals revealed a plasma cell population (Guo et al., 2020).
T266 48493-48616 Sentence denotes In addition, IgG memory cells specific to the RBD have been identified in the blood of COVID-19 patients (Ju et al., 2020).
T267 48617-48873 Sentence denotes Consistent with the development of immunity after COVID-19 infection, a recent study of SARS-CoV-2 infection in rhesus macaques found that two macaques that had resolved the primary infection were resistant to reinfection 28 days later (Bao et al., 2020b).
T268 48874-49049 Sentence denotes Due to the timing of this outbreak, it is not yet possible to know the nature and extent of long-term memory responses, but lessons may again be learned from other human CoVs.
T269 49050-49266 Sentence denotes In the case of the human CoV 229E, specific IgG and nAbs are rapidly induced but wane in some individuals around a year after infection, with some residual protection to reinfection (Callow et al., 1990, Reed, 1984).
T270 49267-49549 Sentence denotes The lifespan of the humoral response following SARS-CoV-1 infection is also relatively short, with the initial specific IgG and nAb response to SARS-CoV-1 diminishing 2–3 years after infection and nearly undetectable in up to 25% of individuals (Cao et al., 2007, Liu et al., 2006).
T271 49550-49806 Sentence denotes A long-term study following 34 SARS-CoV-1-infected healthcare workers over a 13-year period also found that virus-specific IgG declined after several years, but the authors observed detectable virus-specific IgG 12 years after infection (Guo et al., 2020).
T272 49807-49936 Sentence denotes In the case of MERS-CoV, antibodies were detected in six of seven volunteers tested 3 years after infection (Payne et al., 2016).
T273 49937-50129 Sentence denotes IgG specific to SARS-CoV-2 trimeric spike protein was detectable in serum up to 60 days after symptom onset, but IgG titers began decreasing by 8 weeks post symptom onset (Adams et al., 2020).
T274 50130-50216 Sentence denotes Long-term protection from reinfection may also be mediated by reactive memory B cells.
T275 50217-50460 Sentence denotes A study that analyzed SARS-CoV-1 S protein-specific IgG memory cells at 2, 4, 6, and 8 months post infection found that S-specific IgG memory B cells decreased progressively about 90% from 2 to 8 months after infection (Traggiai et al., 2004).
T276 50461-50626 Sentence denotes A further retrospective study of 23 individuals found no evidence of circulating SARS-CoV-1-specific IgG+ memory B cells 6 years after infection (Tang et al., 2011).
T277 50627-50760 Sentence denotes This is in contrast to the memory T cell response, which was robustly detected based on induced IFN-γ production (Tang et al., 2011).
T278 50761-50955 Sentence denotes Studies of common CoVs SARS-CoV-1 and MERS-CoV indicate that virus-specific antibody responses wane over time and, in the case of common CoVs, result in only partial protection from reinfection.
T279 50956-51143 Sentence denotes These data suggest that immunity to SARS-CoV-2 may diminish following a primary infection, and further studies will be required to determine the degree of long-term protection (Figure 4).
T280 51145-51181 Sentence denotes Consequences of the B Cell Response:
T281 51182-51211 Sentence denotes Protection versus Enhancement
T282 51212-51491 Sentence denotes Several studies have demonstrated that high virus-specific antibody titers to SARS-CoV-2 are correlated with greater neutralization of virus in vitro and are inversely correlated with viral load in patients (Figure 4) (Okba et al., 2020, Wölfel et al., 2020, Zhao et al., 2020a).
T283 51492-51833 Sentence denotes Despite these indications of a successful neutralizing response in the majority of individuals, higher titers are also associated with more severe clinical cases (Li et al., 2020b, Okba et al., 2020, Zhao et al., 2020a, Zhou et al., 2020a), suggesting that a robust antibody response alone is insufficient to avoid severe disease (Figure 4).
T284 51834-52039 Sentence denotes This was also observed in the previous SARS-CoV-1 epidemic, where neutralizing titers were found to be significantly higher in deceased patients compared to patients who had recovered (Zhang et al., 2006).
T285 52040-52196 Sentence denotes This has led to concerns that antibody responses to these viruses may contribute to pulmonary pathology via antibody-dependent enhancement (ADE) (Figure 4).
T286 52197-52455 Sentence denotes This phenomenon is observed when non-neutralizing virus-specific IgG facilitate entry of virus particles into Fc-receptor (FcR) expressing cells, particularly macrophages and monocytes, leading to inflammatory activation of these cells (Taylor et al., 2015).
T287 52456-52656 Sentence denotes A study in SARS-CoV-1-infected rhesus macaques found that anti-S IgG contributed to severe acute lung injury (ALI) and massive accumulation of monocytes and macrophages in the lung (Liu et al., 2019).
T288 52657-52825 Sentence denotes Furthermore, serum containing anti-S Ig from SARS-CoV-1 patients enhanced the infection of SARS-CoV-1 in human monocyte-derived macrophages in vitro (Yip et al., 2014).
T289 52826-52933 Sentence denotes ADE was also reported with a monoclonal antibody isolated from a patient with MERS-CoV (Wan et al., 2020c).
T290 52934-53171 Sentence denotes Somewhat reassuringly, there was no evidence of ADE mediated by sera from rats vaccinated with SARS-CoV-2 RBD in vitro (Quinlan et al., 2020) nor in macaques immunized with an inactivated SARS-CoV-2 vaccine candidate (Gao et al., 2020c).
T291 53172-53319 Sentence denotes As of now, there is no evidence that naturally developed antibodies toward SARS-CoV-2 contribute to the pathological features observed in COVID-19.
T292 53320-53446 Sentence denotes However, this possibility should be considered when it comes to experimental design and development of therapeutic strategies.
T293 53447-53581 Sentence denotes Importantly, in all of the descriptions of ADE as it relates to CoV, the FcR was necessary to trigger the antibody-mediated pathology.
T294 53582-53841 Sentence denotes High-dose intravenous immunoglobulin (IVIg), which may blunt ADE, has been trialed in COVID-19 patients (Cao et al., 2020b, Shao et al., 2020), but further studies are needed to determine the extent to which IVIg is safe or beneficial in SARS-CoV-2 infection.
T295 53842-54099 Sentence denotes Vaccine trials will need to consider the possibility of antibody-driven pathology upon antigen rechallenge; strategies using F(ab) fragments or engineered Fc monoclonal antibodies may prove particularly beneficial in this setting (Amanat and Krammer, 2020).
T296 54101-54149 Sentence denotes Predictors of COVID-19 Disease Risk and Severity
T297 54150-54301 Sentence denotes With the rapidly growing number of cases in the first few months, numerous reports on predictors of COVID-19 severity with small cohorts were released.
T298 54302-54475 Sentence denotes These offered clinicians and immunologists the first understanding of the clinical course and pathological processes that are associated with the novel SARS-CoV-2 infection.
T299 54476-54615 Sentence denotes This section highlights key findings from those studies, with a major focus on the immune factors associated with disease risk or severity.
T300 54617-54651 Sentence denotes Susceptibility and Risk Biomarkers
T301 54652-54783 Sentence denotes There are currently limited known risk factors for susceptibility to COVID-19, although this has been evaluated in several studies.
T302 54784-54957 Sentence denotes Zhao et al. compared the ABO blood group distribution in a cohort of 2,173 COVID-19 patients to that of healthy controls from the corresponding regions (Zhao et al., 2020b).
T303 54958-55131 Sentence denotes They found blood group A to be associated with a higher risk for acquiring COVID-19 when compared to non-A blood groups; blood group O had the lowest risk for the infection.
T304 55132-55352 Sentence denotes Another study demonstrated an identical association (Zietz and Tatonetti, 2020), and similar results have been previously described for other viruses (Lindesmith et al., 2003), including SARS-CoV-1 (Cheng et al., 2005a).
T305 55353-55640 Sentence denotes Several large collaborative efforts are currently underway to generate, share, and analyze genetic data to understand the links between human genetic variation and COVID-19 susceptibility and severity, the most prominent of which is the COVID-19 Host Genetics Initiative (covid19hg.org).
T306 55641-55893 Sentence denotes These studies are supported by previous observations on SARS-CoV-1 that followed the 2003 outbreak, which have identified significant associations between genetic variants and immune phenotypes (Chan et al., 2007, Wang et al., 2011, Zhao et al., 2011).
T307 55894-56170 Sentence denotes Although identifying such polymorphisms and their associated genes and pathways for SARS-CoV-2 will require large cohorts, several studies, which remain to be tested in clinical trials, have already highlighted genetic polymorphisms that may potentially impact susceptibility.
T308 56171-56455 Sentence denotes These studies have focused on genetic variants that may impact the expression or function of genes important in viral entry, namely ACE2 (SARS-CoV-2 receptor) and TMPRSS2 (spike protein activator) (Asselta et al., 2020, Cao et al., 2020c, Renieri et al., 2020, Stawiski et al., 2020).
T309 56456-56690 Sentence denotes Cao et al. identified variants that are potentially expression quantitative trait loci (eQTL) of ACE2 (i.e., they may potentially alter ACE2 gene expression) and analyzed their frequencies in different populations (Cao et al., 2020c).
T310 56691-56885 Sentence denotes Stawiski et al. listed variants that may be critical in ACE2 binding and thereby its function and compared the frequencies of these variants within different populations (Stawiski et al., 2020).
T311 56886-57150 Sentence denotes While there are several limitations to these studies, the major question is whether the utility of these biomarkers is replicable in large populations with COVID-19 clinical outcomes data and in targeted or large-scale genomic analyses that are currently underway.
T312 57151-57296 Sentence denotes In addition, these studies will reveal the potential associations between genetic variants and susceptibility in a gene or loci agnostic fashion.
T313 57298-57326 Sentence denotes Routine Bloodwork Biomarkers
T314 57327-57535 Sentence denotes Several routine blood and serological parameters have been suggested to stratify patients who might be at higher risk for complications to aid in allocation of healthcare resources in the pandemic (Table 1 ).
T315 57536-57674 Sentence denotes Serologic markers from routine bloodwork were reported by comparing patients with mild or moderate symptoms to those with severe symptoms.
T316 57675-57804 Sentence denotes This includes different acute phase proteins, such as SAA (serum amyloid protein) and C-reactive protein (CRP) (Ji et al., 2020).
T317 57805-57919 Sentence denotes Interestingly, elevations in CRP appear to be unique to COVID-19 patients when compared to other viral infections.
T318 57920-58162 Sentence denotes Other consistently reported markers in non-survivors are increased procalcitonin (PCT) and IL-6 levels (Huang et al., 2020d), as well as increased serum urea, creatinine, cystatin C, direct bilirubin, and cholinesterase (Xiang et al., 2020a).
T319 58163-58311 Sentence denotes Overall, inflammatory markers are common in severe cases of COVID-19 and appear to correlate with the severity of the symptoms and clinical outcome.
T320 58312-58493 Sentence denotes Moreover, the extensive damage that occurs in specific organs of severe COVID-19 patients is possibly related to differences in the expression of ACE2 (Figure 5 ) (Du et al., 2020).
T321 58494-58576 Sentence denotes Table 1 Routine Blood and Immunological Prognostic Biomarkers in COVID-19 Patients
T322 58577-58594 Sentence denotes Biomarker Purpose
T323 58595-59026 Sentence denotes Routine Bloodwork Lymphocyte count Predicted the disease severity and the outcomes of hospitalized patients (Tan et al., 2020a).Prognostic value was confirmed in numerous studies (Huang et al., 2020d, Liu et al., 2020b, Song et al., 2020, Wang et al., 2020f, Wynants et al., 2020, Yan et al., 2020b, Yang et al., 2020b, Zhang et al., 2020c, Zhao et al., 2020d).Decreased continuously in non-surviving patients (Wang et al., 2020b).
T324 59027-59300 Sentence denotes N/L Patients with N/L ≥3.13 were reported to be more likely to develop severe illness and to require ICU admission (Liu et al., 2020c).N/L on admission was a risk factor for short-term progression of patients with moderate pneumonia to severe pneumonia (Feng et al., 2020).
T325 59301-59430 Sentence denotes Confirmed to be of prognostic value in COVID-19 in several studies (Song et al., 2020, Wynants et al., 2020, Zhou et al., 2020d).
T326 59431-59507 Sentence denotes CRP Proposed as an early biomarker of disease progression (Ji et al., 2020).
T327 59508-59630 Sentence denotes Even in early stages, CRP levels were positively correlated with lung lesions and reflected disease severity (Wang, 2020).
T328 59631-59781 Sentence denotes Confirmed in numerous studies (Fu et al., 2020, Huang et al., 2020d, Wynants et al., 2020, Yan et al., 2020b, Zhao et al., 2020d, Zhou et al., 2020b).
T329 59782-59866 Sentence denotes Predicted the risk of acute myocardial injury (Liu et al., 2020g, Xu et al., 2020a).
T330 59867-59935 Sentence denotes LDH Higher in severe cases than in mild cases (Xiang et al., 2020a).
T331 59936-60072 Sentence denotes Widely proposed to have prognostic value in COVID-19 (Huang et al., 2020d, Wynants et al., 2020, Yan et al., 2020b, Zhao et al., 2020d).
T332 60073-60183 Sentence denotes D-dimer (and coagulation parameters) Predicted severity independently of other variables (Zhou et al., 2020d).
T333 60184-60291 Sentence denotes Elevated levels and disseminated intravascular coagulation are found in non-survivors (Wang et al., 2020b).
T334 60292-60365 Sentence denotes Identified patients at risk for acute cardiac injury (Liu et al., 2020g).
T335 60366-60569 Sentence denotes Other coagulation parameters, such as fibrin degradation product levels, longer prothrombin time, and activated partial thromboplastin time, were also associated with poor prognosis (Tang et al., 2020a).
T336 60570-60716 Sentence denotes SAA SAA was proposed to be used as an auxiliary index for diagnosis as it was elevated in 80% of the patients in a small cohort (Ji et al., 2020).
T337 60717-60886 Sentence denotes NT-proBNP (N-terminal pro B type natriuretic peptide) NT-proBNP was an independent risk factor of in-hospital death in patients with severe COVID-19 (Gao et al., 2020b).
T338 60887-60988 Sentence denotes Platelet count High platelet-to-lymphocyte ratio was associated with worse outcome (Qu et al., 2020).
T339 60989-61129 Sentence denotes Thrombocytopenia was associated with poor outcome and with incidence of myocardial injury in COVID-19 (Liu et al., 2020h, Shi et al., 2020).
T340 61130-61272 Sentence denotes Immunological CD4+, CD8+, and NK cell counts Lower CD4+, CD8+, and NK cells in PBMCs correlated with severity of COVID-19 (Nie et al., 2020b).
T341 61273-61344 Sentence denotes Validated by several studies (Wang et al., 2020f, Zheng et al., 2020b).
T342 61345-61536 Sentence denotes PD-1 and Tim-3 expression on T cells Increasing PD-1 and Tim-3 expression on T cells could be detected as patients progressed from prodromal to overtly symptomatic stages (Diao et al., 2020).
T343 61537-61688 Sentence denotes Expression was higher in infected patients versus healthy controls and in ICU versus non-ICU patients in both CD4 and CD8 T cells (Zhou et al., 2020b).
T344 61689-62013 Sentence denotes phenotypic changes in peripheral blood monocytes The presence of a distinct population of monocytes with high forward scatter (CD11b+, CD14+, CD16+, CD68+, CD80+, CD163+, and CD206+, which secrete IL-6, IL-10, and TNF-α) was identified in patients requiring prolonged hospitalization and ICU admission (Zhang et al., 2020c).
T345 62014-62091 Sentence denotes CD14+CD16+IL-6+ monocytes are increased in ICU patients (Zhou et al., 2020b).
T346 62092-62308 Sentence denotes IP-10, MCP-3, and IL-1ra IP-10, MCP-3, and IL-1ra were, among 48 examined cytokines, the only ones that closely associated with disease severity and outcome of COVID-19 in a study by Yang et al. (Yang et al., 2020b).
T347 62309-62502 Sentence denotes IL-6 Associated with disease severity (hospitalization and ICU admission) and poor prognosis (Chen et al., 2020g, Huang et al., 2020b, Liu et al., 2020b, Liu et al., 2020f, Wang et al., 2020b).
T348 62503-62596 Sentence denotes Increased levels were associated with higher risk of respiratory failure (Yao et al., 2020b).
T349 62597-62737 Sentence denotes IL-8 Positively correlated with disease severity (Chen et al., 2020e, Gong et al., 2020), with severe cases showing the highest IL-8 levels.
T350 62738-62955 Sentence denotes IL-10 Increased in severe or critical patients as compared to mild patients (Gong et al., 2020, Zhou et al., 2020d) without a statistically significant difference between severe and critical cases (Gong et al., 2020).
T351 62956-63149 Sentence denotes IL-2R Associated with disease severity in a study that, among other cytokines, also associated ferroprotein levels, PCT levels, and eosinophil counts with COVID-19 severity (Gong et al., 2020).
T352 63150-63329 Sentence denotes IL-1β CD14+IL-1β+ monocytes are abundant in early-recovery patients as shown in a single-cell RNA-seq analysis and thought to be associated with cytokine storm (Wen et al., 2020).
T353 63330-63464 Sentence denotes IL-1β did not correlate with disease severity in a cross-sectional study with mild, severe, and critical patients (Gong et al., 2020).
T354 63465-63609 Sentence denotes IL-4 IL-4 was associated with impaired lung lesions (Fu et al., 2020), but some reports point to a potential mediator effect (Wen et al., 2020).
T355 63610-63841 Sentence denotes IL-18 In modeling immune cell interaction between DCs and B cells in late recovery COVID-19 patients, IL-18 was found to be important in B cell production of antibodies, which suggests its importance in recovery (Wen et al., 2020).
T356 63842-63914 Sentence denotes GM-CSF GM-CSF+IFN-γ+ T cells are higher in ICU than in non-ICU patients.
T357 63915-64028 Sentence denotes CD14+CD16+GM-CSF+ monocytes are higher in COVID-19 patients as compared to healthy controls (Zhou et al., 2020b).
T358 64029-64129 Sentence denotes IL-2 and IFN-γ IL-2 and IFN-γ levels were shown to be increased in severe cases (Liu et al., 2020b).
T359 64130-64275 Sentence denotes anti-SARS-CoV-2 antibody levels Prolonged SARS-CoV-2 IgM positivity could be utilized as a predictive factor for poor recovery (Fu et al., 2020).
T360 64276-64388 Sentence denotes Higher anti-SARS-CoV-2 IgG levels and higher N/L were more commonly found in severe cases (Zhang et al., 2020a).
T361 64389-64488 Sentence denotes Figure 5 ACE2 Expression in Organs and Systems Most Frequently Implicated in COVID-19 Complications
T362 64489-64571 Sentence denotes The gastrointestinal tract, kidneys, and testis have the highest ACE2 expressions.
T363 64572-64930 Sentence denotes In some organs, different cell types have remarkably distinct expressions; e.g., in the lungs, alveolar epithelial cells have higher ACE2 expression levels than bronchial epithelial cells; in the liver, ACE2 is not expressed in hepatocytes, Kupffer cells, or endothelial cells but is detected in cholangiocytes, which can explain liver injury to some extent.
T364 64931-65032 Sentence denotes Furthermore, ACE2 expression is enriched on enterocytes of the small intestine compared to the colon.
T365 65033-65250 Sentence denotes ACE2, angiotensin-converting enzyme 2; BNP, B-type natriuretic peptide; CRP, C-reactive protein; IL, interleukin; N/L, neutrophil-to-lymphocyte ratio; PT, prothrombin time; aPTT, activated partial thromboplastin time.
T366 65251-65427 Sentence denotes Lymphopenia is the most frequently described prognostic marker in COVID-19 (Table 1), and it appears to predict morbidity and mortality even at early stages (Fei et al., 2020).
T367 65428-65683 Sentence denotes Tan et al. proposed a prognostic model based on lymphocyte counts at two time points: patients with less than 20% lymphocytes at days 10–12 from the onset of symptoms and less than 5% at days 17–19 had the worst outcomes in this study (Tan et al., 2020a).
T368 65684-65936 Sentence denotes Wynants et al. compared predictors of disease severity across seven studies (>1,330 patients), highlighting CRP, neutrophil-to-lymphocyte ratio (N/L), and lactate dehydrogenase (LDH) as the most significant predictive biomarkers (Wynants et al., 2020).
T369 65937-66110 Sentence denotes Furthermore, a meta-analysis of 30 COVID-19 studies with a total of 53,000 patients also attempted to identify early-stage patients with poor prognosis (Zhao et al., 2020d).
T370 66111-66314 Sentence denotes The most consistent findings across the different studies were elevated levels of CRP, LDH, and D-dimer, as well as decreased blood platelet and lymphocyte counts (Yan et al., 2020b, Zhou et al., 2020d).
T371 66315-66713 Sentence denotes Systemic and pulmonary thrombi have been reported with activation of the extrinsic coagulation cascade, involving dysfunctional endothelium and monocytic infiltration (Poor et al., 2020, Varga et al., 2020); thrombocytopenia and elevated D-dimer levels may be indicative of these coagulopathies in COVID-19 patients with important therapeutic implications (Fogarty et al., 2020, Poor et al., 2020).
T372 66715-66763 Sentence denotes Immunological Biomarkers in the Peripheral Blood
T373 66764-66916 Sentence denotes Immunological biomarkers are particularly important, as immunopathology has been suggested as a primary driver of morbidity and mortality with COVID-19.
T374 66917-67022 Sentence denotes Several cytokines and other immunologic parameters have been correlated with COVID-19 severity (Table 1).
T375 67023-67293 Sentence denotes Most notably, elevated IL-6 levels were detected in hospitalized patients, especially critically ill patients, in several studies and are associated with ICU admission, respiratory failure, and poor prognosis (Chen et al., 2020g, Huang et al., 2020b, Liu et al., 2020f).
T376 67294-67544 Sentence denotes Increased IL-2R, IL-8, IL-10, and GM-CSF have been associated with disease severity as well, but studies are limited, and further studies with larger cohorts of patients are needed to indicate predictive power (Gong et al., 2020, Zhou et al., 2020b).
T377 67545-67664 Sentence denotes Conflicting results regarding IL-1β and IL-4 have been reported (Fu et al., 2020, Gong et al., 2020, Wen et al., 2020).
T378 67665-67956 Sentence denotes Although elevated cytokine concentrations have been widely described in COVID-19 patients, the vast majority (including IL-6, IL-10, IL-18, CTACK, and IFN-γ) do not seem to have prognostic value, because they do not always differentiate moderate cases from severe cases (Yang et al., 2020b).
T379 67957-68020 Sentence denotes This stratification was possible with IP-10, MCP-3, and IL-1ra.
T380 68021-68348 Sentence denotes While there are reports that levels of IL-6 at first assessment might predict respiratory failure (Herold et al., 2020), other publications with longitudinal analyses demonstrated that IL-6 increases fairly late during the disease’s course, consequently compromising its prognostic value at earlier stages (Zhou et al., 2020a).
T381 68349-68646 Sentence denotes Liu et al. developed a web-based tool using k-means clustering to predict prognosis in terms of death or hospital discharge of COVID-19 patients using age, comorbidities (binary), and baseline log helper T cell count (TH), log suppressor T cell count (TS), and log TH/TS ratio (Liu et al., 2020e).
T382 68647-68855 Sentence denotes Total T cell, helper T cell, and suppressor T cell counts were significantly lower and the TH/TS ratio was significantly higher in patients who died from infection as compared to patients who were discharged.
T383 68856-69106 Sentence denotes Importantly, most serological and immunological changes observed in severe cases are associated with disease severity but cannot necessarily serve as predictive factors, as they may not have utility in early identification of patients at higher risk.
T384 69107-69315 Sentence denotes Discovery of truly predictive biomarkers and potential drivers of hyperinflammatory processes requires comprehensive profiling of asymptomatic and mild cases and longitudinal studies that are limited to date.
T385 69316-69425 Sentence denotes Confounding variables including age, gender, and comorbidities may dramatically affect associations observed.
T386 69426-69701 Sentence denotes In addition, direct correlation with patient viral load will be important to provide a greater understanding of underlying causes of morbidity and mortality in COVID-19 and the contribution of viral infectivity, hyperinflammation, and host tolerance (Medzhitov et al., 2012).
T387 69702-69909 Sentence denotes In summary, lymphopenia, increases in proinflammatory markers and cytokines, and potential blood hypercoagulability characterize severe COVID-19 cases with features reminiscent of cytokine release syndromes.
T388 69910-70014 Sentence denotes This correlates with a diverse clinical spectrum ranging from asymptomatic to severe and critical cases.
T389 70015-70139 Sentence denotes During the incubation period and early phase of the disease, leukocyte and lymphocyte counts are normal or slightly reduced.
T390 70140-70303 Sentence denotes After SARS-CoV-2 binds to ACE2 overexpressing organs, such as the gastrointestinal tracts and kidneys, increases in non-specific inflammation markers are observed.
T391 70304-70538 Sentence denotes In more severe cases, a marked systemic release of inflammatory mediators and cytokines occurs, with corresponding worsening of lymphopenia and potential atrophy of lymphoid organs, impairing lymphocyte turnover (Terpos et al., 2020).
T392 70540-70550 Sentence denotes Antivirals
T393 70551-70665 Sentence denotes Antivirals are a class of small molecules that function as inhibitors of one or more stages of a virus life cycle.
T394 70666-70805 Sentence denotes Because of similarities between different virus replication mechanisms, some antivirals can be repurposed against various viral infections.
T395 70806-70981 Sentence denotes Currently, most of the available antiviral drugs tested against SARS-CoV-2 are small molecules previously developed against SARS-CoV-1, MERS-CoV, or other RNA and DNA viruses.
T396 70983-71008 Sentence denotes Broad-Spectrum Antivirals
T397 71009-71155 Sentence denotes A number of small molecules with known antiviral activity against other human RNA viruses are being evaluated for efficacy in treating SARS-CoV-2.
T398 71156-71347 Sentence denotes The ribonucleoside analog β-D-N4-hydroxycytidine (NHC) reduced viral titers and lung injury in mice infected with SARS-CoV-2 via introduction of mutations in viral RNA (Sheahan et al., 2017).
T399 71348-71574 Sentence denotes Further, an inhibitor of host DHODH, a rate-limiting enzyme in pyrimidine synthesis, was able to inhibit SARS-CoV-2 growth in vitro with greater efficacy than remdesivir or chloroquine (Wang et al., 2020e, Xiong et al., 2020).
T400 71575-71796 Sentence denotes Merimepodib, a non-competitive inhibitor of the enzyme inosine-5′-monophosphate dehydrogenase (IMPDH), involved in host guanosine biosynthesis, is able to suppress SARS-CoV-2 replication in vitro (Bukreyeva et al., 2020).
T401 71797-72094 Sentence denotes Finally, N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC), which was previously shown to efficiently reduce infection by the less-pathogenic human CoV HCoV-NL63, was also found to inhibit MERS-CoV and pseudotyped SARS-CoV-2 in human airway epithelial cells (Milewska et al., 2020).
T402 72096-72115 Sentence denotes Protease Inhibitors
T403 72116-72260 Sentence denotes Much of the antiviral computational and experimental data currently available for SARS-CoV-2 focus on targeting the 3CL or Main protease (Mpro).
T404 72261-72420 Sentence denotes Two prominent drug candidates targeting the SARS-CoV-2 Mpro were designed and synthesized by analyzing the substrate binding pocket of Mpro (Dai et al., 2020).
T405 72421-72529 Sentence denotes The X-ray crystal structures of the novel inhibitors in complex with SARS-CoV-2 Mpro were resolved at 1.5 Å.
T406 72530-72654 Sentence denotes Both compounds showed good pharmacokinetic activity in vitro, and one exhibited limited toxicity in vivo (Dai et al., 2020).
T407 72655-72744 Sentence denotes Multiple studies also aimed to repurpose protease inhibitors to reduce SARS-CoV-2 titers.
T408 72745-73067 Sentence denotes Nine existing HIV protease inhibitors (nelfinavir, lopinavir, ritonavir, saquinavir, atazanavir, tipranavir, amprenavir, darunavir, and indinavir) were evaluated for their antiviral activity in Vero cells infected with SARS-CoV-2 (Yamamoto et al., 2020), and nelfinavir was the most potent at inhibiting viral replication.
T409 73069-73084 Sentence denotes RdRp Inhibitors
T410 73085-73273 Sentence denotes The CoV RNA-dependent RNA polymerase (RdRp) catalyzes the synthesis of viral RNA (Gao et al., 2020a), making it essential for viral replication and a prime target for antiviral inhibitors.
T411 73274-73497 Sentence denotes Remdesivir, an adenosine triphosphate analog, inhibits RdRp by binding to RNA strands and preventing additional nucleotides from being added, thereby terminating viral RNA transcription (Figure 6 A) (Agostini et al., 2018).
T412 73498-73655 Sentence denotes Remdesivir has been previously shown to be effective against MERS-CoV and SARS-CoV-1 infections in animal models (Sheahan et al., 2017, de Wit et al., 2020).
T413 73656-73801 Sentence denotes Similarly, a study investigated the efficacy of remdesivir treatments on 12 rhesus macaques with SARS-CoV-2 infections (Williamson et al., 2020).
T414 73802-73932 Sentence denotes Macaques treated with remdesivir showed a reduction in lung viral loads and pneumonia symptoms but no reduction in virus shedding.
T415 73933-74063 Sentence denotes This study does provide evidence that if administered early enough, remdesivir may be effective at treating SARS-CoV-2 infections.
T416 74064-74168 Sentence denotes Figure 6 Available Therapeutic Options to Manage COVID-19 Immunopathology and to Deter Viral Propagation
T417 74169-74383 Sentence denotes (A) Rdrp inhibitors (remdesivir, favipiravir), protease inhibitors (lopinavir/ritonavir), and antifusion inhibitors (arbidol) are currently being investigated in their efficacy in controlling SARS-CoV-2 infections.
T418 74384-74491 Sentence denotes (B) CQ and HCQ increase the pH within lysosomes, impairing viral transit through the endolysosomal pathway.
T419 74492-74640 Sentence denotes Reduced proteolytic function within lysosomes augments antigen processing for presentation on MHC complexes and increases CTLA4 expression on Tregs.
T420 74641-74776 Sentence denotes (C) Antagonism of IL-6 signaling pathway and of other cytokine-/chemokine-associated targets has been proposed to control COVID-19 CRS.
T421 74777-74897 Sentence denotes These include secreted factors like GM-CSF that contribute to the recruitment of inflammatory monocytes and macrophages.
T422 74898-75114 Sentence denotes (D) Several potential sources of SARS-CoV-2 neutralizing antibodies are currently under investigation, including monoclonal antibodies, polyclonal antibodies, and convalescent plasma from recovered COVID-19 patients.
T423 75115-75250 Sentence denotes GM-CSF, granulocyte-macrophage colony-stimulating factor; CQ, chloroquine; HCQ, hydroxychloroquine; RdRp, RNA-dependent RNA polymerase.
T424 75252-75277 Sentence denotes Antiviral Clinical Trials
T425 75278-75370 Sentence denotes A large number of clinical trials using experimental antiviral drugs are currently underway.
T426 75371-75732 Sentence denotes A small proportion of them are aimed at repurposing existing antivirals, including arbidol (umifenovir), a broad-spectrum antiviral that blocks viral fusion; lopinavir/ritonavir (LPV/r), a combination of anti-HIV protease inhibitors; favipiravir, an RdRp inhibitor used to treat severe influenza infections (Hayden and Shindo, 2019); and remdesivir (Figure 6A).
T427 75733-75898 Sentence denotes Chen et al. conducted a multicenter, randomized priority trial on 240 patients with confirmed COVID-19 infection to test favipiravir or arbidol (Chen et al., 2020b).
T428 75899-75965 Sentence denotes Favipiravir was suggested to significantly improve symptom relief.
T429 75966-76148 Sentence denotes However, the interpretation of this study is limited by a short clinical recovery window of 7 days, only 100 of 236 patients with confirmed COVID-19, and the lack of a control group.
T430 76149-76292 Sentence denotes LPV/r has previously shown efficacy in treating SARS-Cov-1 (Chu et al., 2004), prompting an early SARS-Cov-2 clinical trial (Li et al., 2020c).
T431 76293-76476 Sentence denotes 44 patients were enrolled in a trial investigating the efficacy and safety of LPV/r (n = 21 patients), arbidol (n = 16), or control (n = 7) as treatment for mild to moderate COVID-19.
T432 76477-76680 Sentence denotes At day 14 of treatment, 76.2%, 62.4%, and 71.4% of patients had a positive to negative conversion in the LPV/r, arbidol, and control groups, respectively, with no statistical significance between groups.
T433 76681-76825 Sentence denotes A randomized controlled trial (RCT) with 200 severe COVID-19 patients did not observe a significant benefit of LPV/r either (Cao et al., 2020a).
T434 76826-77045 Sentence denotes However, a study that looked at the impact of earlier administration of LPV/r treatment showed that when treatment of LPV/r was started within 10 days of symptom onset, a shorter duration of virus shedding was observed.
T435 77046-77135 Sentence denotes Thus, timing of LPV/r administration may be critical to its efficacy (Yan et al., 2020a).
T436 77136-77342 Sentence denotes In a multicenter clinical study assessing the compassionate use of remdesivir in severe COVID-19 patients, 53 patients across several countries were treated with remdesivir for 10 days (Grein et al., 2020).
T437 77343-77474 Sentence denotes 68% of the 53 patients who received remdesivir showed clinical improvement assessed through improved oxygen support or extubations.
T438 77475-77599 Sentence denotes Without a proper control group, limited conclusions can be drawn with regards to the efficacy of remdesivir from this study.
T439 77600-77752 Sentence denotes The measured 68% clinical improvement may be in line with average clinical improvement across patients treated with standard of care (Li et al., 2020c).
T440 77753-77941 Sentence denotes A small RCT in China with 237 severe COVID-19 patients randomized 2:1 to remdesivir versus placebo demonstrated no significant benefit in time to clinical improvement (Wang et al., 2020g).
T441 77942-78173 Sentence denotes Almost simultaneously, preliminary results from a larger National Institute of Allergy and Infectious Diseases (NIAID) RCT with more than 1,000 patients were announced with remdesevir to be associated with quicker time to recovery:
T442 78174-78220 Sentence denotes 11 days compared with 15 days (Ledford, 2020).
T443 78221-78357 Sentence denotes A non-significant benefit in mortality was also noted, and the trial was stopped early to allow access to remdesivir in the placebo arm.
T444 78358-78559 Sentence denotes Complete safety data and full publication are awaited, but this study offers encouraging results and has resulted in an FDA emergency use authorization for remdesivir in hospitalized COVID-19 patients.
T445 78561-78612 Sentence denotes Therapeutic Immunomodulation for COVID-19 Treatment
T446 78614-78626 Sentence denotes Chloroquine:
T447 78627-78667 Sentence denotes Modes of Action and Immunological Impact
T448 78668-78788 Sentence denotes Chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) have gained traction as possible therapeutics for COVID-19.
T449 78789-78893 Sentence denotes Both drugs are used as antimalarial agents and as immunomodulatory therapies for rheumatologic diseases.
T450 78894-79081 Sentence denotes However, the application of CQ and HCQ to COVID-19 stems from their past use as antivirals (Savarino et al., 2003), including for SARS-CoV-1 (Keyaerts et al., 2004, Vincent et al., 2005).
T451 79082-79183 Sentence denotes CQ and HCQ interfere with lysosomal activity and have been reported to have immunomodulatory effects.
T452 79184-79457 Sentence denotes CQ augments antigen processing for MHC class I and II presentation, directly inhibits endosomal TLR7 and TLR9, and enhances the activity of regulatory T cells (Garulli et al., 2008, Lo et al., 2015, Schrezenmeier and Dörner, 2020, Thomé et al., 2013a, Thomé et al., 2013b).
T453 79458-79686 Sentence denotes Early studies involving in vitro infection of host cells with SARS-CoV-2 demonstrated that both CQ and HCQ significantly impact endosomal maturation, resulting in increased sequestration of virion particles within endolysosomes.
T454 79687-79849 Sentence denotes However, there has been conflicting evidence whether CQ is more potent than HCQ in reducing viral load (Liu et al., 2020d, Wang et al., 2020b, Yao et al., 2020a).
T455 79850-80092 Sentence denotes Notably, one group reported that treatment of infected cells with HCQ before and during infection significantly reduced viral load, suggesting that combined prophylactic and therapeutic HCQ use yields maximum efficacy (Clementi et al., 2020).
T456 80093-80448 Sentence denotes To better understand host immune responses to treatment, one group compared bulk transcriptomic changes in primary PBMCs treated with HCQ for 24 h to PBMCs from confirmed SARS-CoV-2 positive patients and controls, followed by a comparison of HCQ-treated primary macrophages to BAL and postmortem lung biopsies from COVID-19 patients (Corley et al., 2020).
T457 80449-80585 Sentence denotes Across all comparisons, there was minimal overlap between host differential gene expression and genes altered by in vitro HCQ treatment.
T458 80586-80684 Sentence denotes Thus, the potential mechanistic action of HCQ in the context of SARS-CoV-2 remains poorly defined.
T459 80686-80731 Sentence denotes Evaluation of HCQ Efficacy in Clinical Trials
T460 80732-80953 Sentence denotes Despite the apparent widespread use of HCQ and CQ to treat COVID-19 (Figure 6B), few controlled clinical trials have been performed so far and thus the potential benefits of these drugs for COVID-19 remains controversial.
T461 80954-81077 Sentence denotes One of the earliest trials (2020-000890-25) was a single-arm, open-label trial of 600 mg daily HCQ in 20 COVID-19 patients.
T462 81078-81217 Sentence denotes They reported that HCQ alone, or in combination with the antibiotic azithromycin (AZ), reduced viral load by day 6 (Gautret et al., 2020a).
T463 81218-81408 Sentence denotes A follow-up trial in 80 patients treated with HCQ and AZ reported that 93% of patients had a negative PCR result on day 8 of treatment, and 81.3% were discharged within 10 days of treatment.
T464 81409-81503 Sentence denotes However, it is important to note that both trials had no control arms (Gautret et al., 2020b).
T465 81504-81689 Sentence denotes Rigorous statistical analyses by others that accounted for the patients excluded from the original analysis found limited evidence for HCQ monotherapy (Hulme et al., 2020, Lover, 2020).
T466 81690-81808 Sentence denotes A double-blind RCT assessed HCQ monotherapy in the treatment of mild COVID-19 (ChiCTR2000029559) (Chen et al., 2020i).
T467 81809-81903 Sentence denotes A total of 62 patients were enrolled; the treatment arm received 400 mg HCQ daily over 5 days.
T468 81904-82090 Sentence denotes By day 6, patients who received HCQ had clinical resolution on average 1 day earlier than controls; no patients progressed to severe disease compared to four patients in the control arm.
T469 82091-82460 Sentence denotes In a smaller RCT that treated 30 patients with mild COVID-19 (NCT04261517) with 400 mg HCQ for 7 days, there were no significant differences in the number of patients with negative PCR results on day 7 (all but one positive), median duration of hospitalization, time to fever resolution, or progression of disease on chest computed tomography (CT) (Chen et al., 2020d).
T470 82461-82614 Sentence denotes The largest RCT to date enrolled 150 patients with mild COVID-19 across 16 centers in an open-label trial of HCQ and standard of care (ChiCTR2000029868).
T471 82615-83038 Sentence denotes There were no significant differences between groups in conversion to negative SARS-CoV-2 RT-PCR result on day 28 or rate of symptom resolution; there were significantly more adverse events in the HCQ arm, though largely non-serious; they reported some evidence for faster normalization of C-reactive protein in the patients who received HCQ plus standard of care, but this finding was not significant (Tang et al., 2020b).
T472 83039-83213 Sentence denotes A meta-analysis including most of the studies described here found no clinical benefits to patients receiving standard of care plus an HCQ regimen (Shamshirian et al., 2020).
T473 83214-83272 Sentence denotes Two studies have assessed HCQ efficacy in severe COVID-19.
T474 83273-83522 Sentence denotes In a prospective study of 11 patients who had received 600 mg HCQ over 10 days with AZ on days 1–5, there were several patients with worsening clinical status and one death; 8 of 10 patients had a positive PCR result on day 10 (Molina et al., 2020).
T475 83523-83746 Sentence denotes An ongoing double-blind RCT of patients with severe COVID-19 (NCT04323527) randomized 81 patients into high-dose HCQ (600 mg 2× per day for 10 days) or low-dose (450 mg/day for 5 days) treatment groups (Borba et al., 2020).
T476 83747-83833 Sentence denotes Recruitment into the high-dose arm was halted prematurely due to poor safety outcomes.
T477 83834-83947 Sentence denotes There was no significant difference in negative PCR results on day 4 or need for mechanical ventilation on day 6.
T478 83948-84142 Sentence denotes Taken together, the clinical trials performed thus far to evaluate the efficacy of HCQ ± AZ for COVID-19 have not demonstrated clear evidence of clinical benefit in patients with severe disease.
T479 84143-84236 Sentence denotes A search of ClinicalTrials.gov on April 27, 2020 found 140 clinical trials investigating HCQ.
T480 84237-84377 Sentence denotes This number is rapidly growing, indicating the heightened interest in this therapeutic and pressing need for evidence-based recommendations.
T481 84379-84415 Sentence denotes Corticosteroids for COVID-19 Therapy
T482 84416-84535 Sentence denotes Because of their anti-inflammatory activity, corticosteroids (CSs) are an adjuvant therapy for ARDS and cytokine storm.
T483 84536-84713 Sentence denotes However, the broad immunosuppression mediated by CS does raise the possibility that treatment could interfere with the development of a proper immune response against the virus.
T484 84714-84886 Sentence denotes A meta-analysis of 5,270 patients with MERS-CoV, SARS-CoV-1, or SARS-CoV-2 infection found that CS treatment was associated with higher mortality rate (Yang et al., 2020c).
T485 84887-85104 Sentence denotes A more recent meta-analysis of only SARS-CoV-2 infection assessed 2,636 patients and found no mortality difference associated with CS treatment, including in a subset of patients with ARDS (Gangopadhyay et al., 2020).
T486 85105-85252 Sentence denotes Other studies have reported associations with delayed viral clearance and increased complications in SARS and MERS patients (Sanders et al., 2020).
T487 85253-85417 Sentence denotes In fact, the interim guidelines updated by the WHO on March 13, 2020 advise against giving systemic corticosteroids for COVID-19 (World Health Organization, 2020a).
T488 85418-85462 Sentence denotes Yet, new data from COVID-19 are conflicting.
T489 85463-85681 Sentence denotes One group reported no significant difference in time to viral clearance between patients who received methylprednisolone orally (mild disease) or intravenously (i.v.) (severe) and those who did not (Fang et al., 2020).
T490 85682-85943 Sentence denotes Retrospective studies from groups in China report that patients who were transferred to the ICU were less likely to have received CSs (Wang et al., 2020b) and that patients with ARDS who received methylprednisolone had reduced mortality risk (Wu et al., 2020a).
T491 85944-86188 Sentence denotes In contrast, another retrospective analysis found that patients who received CSs were more likely to have either been admitted to the ICU or perished, although the CS-treated group also had significantly more comorbidities (Wang et al., 2020c).
T492 86189-86381 Sentence denotes A smaller observational study of 31 patients found no association between corticosteroid treatment and time to viral clearance, length of hospital stay, or symptom duration (Zha et al., 2020).
T493 86382-86625 Sentence denotes A larger study of adjuvant CSs in 244 patients with critical COVID-19 found no association with 28-day mortality; subgroup analysis of patients with ARDS found no association between treatment with CSs and clinical outcomes (Lu et al., 2020b).
T494 86626-86723 Sentence denotes They also found that increased dosage was significantly associated with increased mortality risk.
T495 86724-86979 Sentence denotes A retrospective review of 46 patients, of whom 26 received i.v. methylprednisolone, found that early, low-dose administration significantly improved SpO2 and chest CT, time to fever resolution, and time on supplemental oxygen therapy (Wang et al., 2020h).
T496 86980-87167 Sentence denotes Others have published perspectives in support of early (Lee et al., 2020) and short-term, low-dose administration (Shang et al., 2020) based on anecdotal evidence but not clinical trials.
T497 87168-87314 Sentence denotes Most of the current data on CS use in COVID-19 are from observational studies and support either modest clinical benefit or no meaningful effects.
T498 87315-87514 Sentence denotes Larger RCTs are necessary to understand the risks and benefits of CSs for these patients; there are 22 trials evaluating various corticosteroids registered on ClinicalTrials.gov as of April 27, 2020.
T499 87516-87553 Sentence denotes Cytokine-Directed Therapy in COVID-19
T500 87555-87596 Sentence denotes Recombinant IFN as an Antiviral Treatment
T501 87597-87716 Sentence denotes One of the first defenses of the human body against RNA viruses like SARS-CoV-2 is the release of types I and III IFNs.
T502 87717-87947 Sentence denotes It is important to note that type I IFN (IFNα/β) receptors are ubiquitously expressed, so IFNα/β signaling can result in not only antiviral effects, but also the activation of immune cells that potentially exacerbate pathogenesis.
T503 87948-88079 Sentence denotes In contrast, type III IFN (also known as IFNλ) signals mainly in epithelial cells, as well as in a restricted pool of immune cells.
T504 88080-88293 Sentence denotes Because type III IFNs have immunomodulatory functions, subsequent signaling could induce a potent antiviral effect without enhancing pathogenic inflammation (Andreakos et al., 2017, Prokunina-Olsson et al., 2020).
T505 88294-88438 Sentence denotes Recently, there has been a growing interest in the potential therapeutic impact of modulating the IFN response to disable COVID-19 pathogenesis.
T506 88439-88541 Sentence denotes Before the current pandemic, groups have studied the role of IFNs in other betacoronavirus infections.
T507 88542-88695 Sentence denotes One study of 40 patients with SARS-CoV-1 infection described unresolved elevated type I IFNs and ISGs in those with poor outcomes (Cameron et al., 2007).
T508 88696-88975 Sentence denotes Others report that exogenous type I IFN does not improve outcomes when given with ribavirin in patients with MERS-CoV infection (Arabi et al., 2020), suggesting that the role of IFN as a therapeutic or prophylactic option may be strain or species specific (Sheahan et al., 2020).
T509 88976-89226 Sentence denotes Interestingly, a recent study by Mount Sinai virology groups revealed that type I IFN signaling is impaired in the early response to SARS-CoV-2; in vitro, SARS-CoV-2 may be more susceptible to type I IFN than SARS-CoV-1 is (Blanco-Melo et al., 2020).
T510 89227-89513 Sentence denotes Based on additional evidence that IFN responses to betacoronaviruses are altered as compared to other respiratory viruses (Blanco-Melo et al., 2020, Channappanavar et al., 2016, Okabayashi et al., 2006), trials of IFN-I/III administration have been initiated (NCT04343976, NCT04331899).
T511 89515-89532 Sentence denotes Cytokine Blockade
T512 89533-89807 Sentence denotes Hyperinflammatory responses and elevated levels of inflammatory cytokines, including IL-6, -8, and -10, have been shown to correlate with COVID-19 severity (Chen et al., 2020h, Diao et al., 2020, Gong et al., 2020, Moore and June, 2020, Wan et al., 2020a, Xu et al., 2020b).
T513 89808-89965 Sentence denotes The drivers of this cytokine storm remain to be established, but they are likely triggered initially by a combination of viral PAMPs and host danger signals.
T514 89966-90124 Sentence denotes The heterogeneous response between patients suggests other factors are involved, possibly including the SARS-CoV-2 receptor, ACE2 (Hirano and Murakami, 2020).
T515 90125-90256 Sentence denotes Several studies have begun to report the cellular programs that may contribute to the cytokine storm detected in COVID-19 patients.
T516 90257-90511 Sentence denotes One group reported that in the context of generalized lymphopenia, certain subsets of CD4 T cells that express GM-CSF and IL-6 are more abundant in severe COVID-19 patients than in COVID-19 patients who do not require intensive care (Zhou et al., 2020b).
T517 90512-90750 Sentence denotes Reports that other major proinflammatory cytokines (TNF-α, IFN-ɣ, IL-2) and chemokines (CCL2, CCL3, CCL4) are elevated underscore a potentially pathogenic TH1/2 program in COVID-19 (Diao et al., 2020, Giamarellos-Bourboulis et al., 2020).
T518 90751-91021 Sentence denotes Histological and single-cell analyses identified monocytes and macrophages as other potent sources of inflammatory cytokines in COVID-19 cytokine storm (Chen et al., 2020h, Giamarellos-Bourboulis et al., 2020, Law et al., 2005, Moore and June, 2020, Zhou et al., 2020b).
T519 91022-91400 Sentence denotes Studies of other betacoronavirus infections, including SARS-CoV-1 and MERS-CoV, have also identified similar hyperactivation of monocytes, macrophages, and DCs as a driver of cytokine-mediated immunopathology in humans (Cheung et al., 2005, Chien et al., 2006, Huang et al., 2020c, Konig et al., 2020, Wang et al., 2005, Wong et al., 2004, Xu et al., 2020b, Zhou et al., 2020b).
T520 91401-91631 Sentence denotes Following preliminary reports of IL-6 as a critical cytokine in COVID-19-associated CRS, monoclonal antibodies that target the IL-6 signaling pathway have been proposed as therapeutic candidates (Moore and June, 2020) (Figure 6C).
T521 91632-91877 Sentence denotes The commercial anti-IL-6R antibodies tocilizumab (Actemra) and sarilumab (Kevzara) and the anti-IL-6 antibody siltuximab (Sylvant) are now being tested for efficacy in managing COVID-19 CRS and pneumonia in 13 ongoing clinical trials (Table 2 ).
T522 91878-92140 Sentence denotes To date, only one group has reported preliminary results from a cohort of 20 COVID-19 patients treated with a single administration of tocilizumab (400 mg, i.v.), along with lopinavir, methylprednisolone, and oxygen therapy (ChiCTR2000029765) (Xu et al., 2020b).
T523 92141-92328 Sentence denotes The single observation study found recuperated lymphocyte counts in 10 of 19 patients and resolution of lung opacities in 19 of 20 patients on chest CT; 19 of 20 patients were discharged.
T524 92329-92435 Sentence denotes All patients experienced an improvement in symptoms, and no subsequent pulmonary infections were reported.
T525 92436-92571 Sentence denotes A second report described an association between use of tocilizumab and reduced likelihood of ICU admission and mechanical ventilation.
T526 92572-92757 Sentence denotes Still, in 30 declining patients with severe COVID-19 pneumonia, this retrospective study did not report significant improvement in mortality on weighted analysis (Roumier et al., 2020).
T527 92758-92863 Sentence denotes Nevertheless, these studies are encouraging, but like other treatment approaches, larger RCTs are needed.
T528 92864-92942 Sentence denotes Table 2 Clinical Trials Evaluating the Efficacy of IL-6/IL-6R Blockade Therapy
T529 92943-92970 Sentence denotes Clinical Trial Intervention
T530 92971-93119 Sentence denotes NCT04331795 (COVIDOSE)NCT04320615 (COVACTA)NCT04332913 (TOSCA)NCT04317092 (TOCOVID-19)NCT04335071 (CORON-ACT)NCT04315480ChiCTR2000029765 tocilizumab
T531 93120-93141 Sentence denotes NCT04315298 sarilumab
T532 93142-93176 Sentence denotes NCT04310228 tocilizumabfavipiravir
T533 93177-93260 Sentence denotes NCT04306705 (TACOS) tocilizumabcontinuous renal replacement therapystandard of care
T534 93261-93324 Sentence denotes NCT04332094 (TOCOVID) tocilizumabazithromycinhydroxychloroquine
T535 93325-93392 Sentence denotes NCT04341870 (CORIMUNO-VIRO) sarilumabazithromycinhydroxychloroquine
T536 93393-93460 Sentence denotes NCT0433z638 (COV-AID) tocilizumabsiltuximabanakinrastandard of care
T537 93461-93701 Sentence denotes In addition to the IL-6 signaling pathway, other cytokine- and chemokine-associated elements, including IL-1R, GM-CSF, and the chemokine receptor CCR5, have been proposed as potential targets for blockade to manage COVID-19 CRS (Figure 6C).
T538 93702-93793 Sentence denotes Finally, complement activation was shown to be overactivated in lungs of COVID-19 patients.
T539 93794-93973 Sentence denotes Although results from the randomized trial are not yet published, anti-C5a monoclonal antibody therapy showed benefits in two critically ill COVID-19 patients (Gao et al., 2020d).
T540 93975-94043 Sentence denotes Neutralizing Antibodies and Convalescent Plasma Therapy for COVID-19
T541 94044-94249 Sentence denotes While vaccines are being developed to educate a person’s immune system to make their own nAbs against SARS-CoV-2, there is interest in using adoptive transfer of nAbs as a therapeutic approach (Figure 6D).
T542 94250-94505 Sentence denotes This strategy has already proven to be effective against SARS-CoV-1 (Cao et al., 2010, Ho et al., 2005, ter Meulen et al., 2004, Park et al., 2020, Sui et al., 2004, Zhu et al., 2007) and MERS-CoV (Forni et al., 2015, Jia et al., 2019, Ying et al., 2015).
T543 94506-94678 Sentence denotes In the case of SARS-CoV-2, these efforts are primarily centered on identifying nAbs made during natural infections or generating nAbs through animal vaccination approaches.
T544 94680-94715 Sentence denotes nAbs Derived from COVID-19 Patients
T545 94716-94901 Sentence denotes Patients who have recovered from SARS-CoV-2 infection are one potential source of nAbs (Chen et al., 2020a, Ju et al., 2020, Walls et al., 2020, Wölfel et al., 2020, Yuan et al., 2020).
T546 94902-95132 Sentence denotes In an effort to obtain these nAbs, scientists sorted RBD-specific memory B cells and cloned their heavy and light variable regions to express recombinant forms of the corresponding antibodies (Chen et al., 2020a, Ju et al., 2020).
T547 95133-95294 Sentence denotes Four of the antibodies produced in these studies (31B5, 32D4, P2C-2F6, P2C-1F11) showed high neutralizing potential in vitro, and all inhibited ACE2-RBD binding.
T548 95295-95414 Sentence denotes Successful antibody-mediated neutralization of SARS-CoV-2 seemed to be dependent on the inhibition of ACE2/RBD binding.
T549 95415-95609 Sentence denotes However, Chen et al. showed that nearly all antibodies derived from serum of 26 recovered patients bound to S1 and RBD, with only three actually inhibiting ACE2/RBD binding (Chen et al., 2020a).
T550 95610-95847 Sentence denotes Of note, a SARS-CoV-1-derived neutralizing antibody (47D11) (Wang et al., 2020a) and a single-chain antibody against SARS-CoV-2 (n3130) (Wu et al., 2020c) have also been shown to neutralize SARS-CoV-2 without inhibiting ACE2/RBD binding.
T551 95848-95938 Sentence denotes Thus, blocking this interaction may not be a prerequisite for an effective SARS-CoV-2 nAb.
T552 95939-96183 Sentence denotes The generation of a hybridoma producing a monoclonal nAb against SARS-CoV-2 provides the potential for a therapeutic Ab that can be directly administered to patients to block ongoing infection and potentially even as a prophylactic (Figure 6D).
T553 96185-96227 Sentence denotes SARS-CoV-1 nAbs Also Neutralize SARS-CoV-2
T554 96228-96318 Sentence denotes SARS-CoV-1 and SARS-CoV-2 consensus sequences share about 80% identity (Tai et al., 2020).
T555 96319-96488 Sentence denotes Thus, a wide range of SARS-CoV-1 nAbs have been tested for crossreactivity with SARS-CoV-2, as they could help speed up the development of potential COVID-19 treatments.
T556 96489-96614 Sentence denotes In a recent study, antibodies were isolated from the memory B cells of an individual who recovered from SARS-CoV-1 infection.
T557 96615-96768 Sentence denotes While 8 out of 25 isolated antibodies could bind SARS-CoV-2 S protein, one of them (s309; see Table 3 ) also neutralizes SARS-CoV-2 (Pinto et al., 2020).
T558 96769-96904 Sentence denotes The combination of s309 with a weakly neutralizing antibody that could bind another RBD epitope led to enhanced neutralization potency.
T559 96905-97058 Sentence denotes In addition, CR3022 (Table 3) was found to bind SARS-CoV-2 RBD (Tian et al., 2020b), but this antibody did not neutralize SARS-CoV-2 (Yuan et al., 2020).
T560 97059-97273 Sentence denotes Computational simulations identified three amino acids that could be modified on CR3022 to enhance its binding affinity with SARS-CoV-2 RBD (Giron et al., 2020), potentially augmenting its neutralization potential.
T561 97274-97338 Sentence denotes Table 3 Strategies to Isolate SARS-CoV-2 Neutralizing Antibodies
T562 97339-97434 Sentence denotes Ab Source Clone Target Type of Antibody Neutralization Inhibition of ACE2/RBD Binding Reference
T563 97435-97522 Sentence denotes Derived from COVID-19 patients 31B532D4 RBD human monoclonal yes yes Chen et al., 2020a
T564 97523-97583 Sentence denotes P2C-2F6P2C-1F11 RBD human monoclonal yes yes Ju et al., 2020
T565 97584-97708 Sentence denotes Derived from SARS-CoV-1 patients CR3022 RBD human monoclonal no no Tian et al., 2020b, Yuan et al., 2020, Giron et al., 2020
T566 97709-97760 Sentence denotes S309 RBD human monoclonal yes no Pinto et al., 2020
T567 97761-97870 Sentence denotes Derived from SARS-CoV-1 or MERS-CoV-1 animal models R325R302R007 S1 rabbit monoclonal yes no Sun et al., 2020
T568 97871-97994 Sentence denotes 47D11 S1 recombinant human monoclonal (derived from hybridomas of immunized transgenic H2L2 mice) yes no Wang et al., 2020a
T569 97995-98069 Sentence denotes VHH-72-Fc S Fc-fusion derived from camelids VHH yes yes Wrapp et al., 2020
T570 98070-98145 Sentence denotes S polyclonal mouse antibodies yes N/A Walls et al., 2020, Yuan et al., 2020
T571 98146-98222 Sentence denotes Other ACE2-Fc RBD ACE2-Fc fusion yes N/A Lei et al., 2020a, Li et al., 2020d
T572 98223-98273 Sentence denotes RBD-Fc ACE2 RBD-Fc fusion yes N/A Li et al., 2020d
T573 98274-98372 Sentence denotes N3130 S1 human monoclonal single domain antibody isolated by phage display yes no Wu et al., 2020c
T574 98373-98448 Sentence denotes IVIg N/A polyclonal human IVIg N/A N/A Díez et al., 2020, Shao et al., 2020
T575 98449-98502 Sentence denotes F(ab′)2 RBD horse polyclonal yes N/A Pan et al., 2020
T576 98503-98521 Sentence denotes N/A, not assessed.
T577 98523-98548 Sentence denotes nAbs Derived from Animals
T578 98549-98632 Sentence denotes Animal models represent another tool to generate nAbs against SARS-CoV-2 (Table 3).
T579 98633-98839 Sentence denotes In one study, the authors developed a protocol to synthetize human nanobodies, smaller antibodies that only contain a variable heavy (VH) chain as first described in camelids (Wu et al., 2020c) (Figure 6D).
T580 98840-99048 Sentence denotes Another antibody isolated from camelids immunized with SARS-CoV-1 and MERS-CoV S proteins then fused to a human Fc fragment showed neutralization potential against SARS-CoV-2 (VHH-72-Fc) (Wrapp et al., 2020).
T581 99049-99233 Sentence denotes Genetically modified mice with humanized antibody genes can also be used to generate therapeutic monoclonal antibodies, as successfully experimented against Ebola virus (Levine, 2019).
T582 99234-99542 Sentence denotes Similar studies are now focused on the use of SARS-CoV-2 or derivatives to generate highly effective nAb in animal models, which can be directly given to infected patients, and efforts are already underway with estimates of clinical trials of pooled antibody cocktails beginning in early summer by Regeneron.
T583 99543-99728 Sentence denotes Finally, another approach to nAb development is to fuse ACE2 protein and the Fc part of antibodies, as they would bind RBD and potentially be crossreactive among other CoVs (Figure 6D).
T584 99729-99871 Sentence denotes Indeed, an ACE2-Fc (Lei et al., 2020a) and an RBD-Fc (Li et al., 2020d) have been shown to neutralize both SARS-CoV-1 and SARS-CoV-2 in vitro.
T585 99873-99900 Sentence denotes Convalescent Plasma Therapy
T586 99901-100106 Sentence denotes Although recombinant nAbs could provide an effective treatment, they will require a significant time investment to develop, test, and bring production to scale before becoming widely available to patients.
T587 100107-100283 Sentence denotes A faster strategy consists of transferring convalescent plasma (CP) from previously infected individuals that have developed high titer nAbs that target SARS-CoV-2 (Figure 6D).
T588 100284-100569 Sentence denotes Despite the current lack of appropriately controlled trials, CP therapy has been previously used and shown to be beneficial in several infectious diseases, such as the 1918 influenza pandemic (Luke et al., 2006), H1N1 influenza (Hung et al., 2011), and SARS-CoV-1 (Arabi et al., 2016).
T589 100570-100787 Sentence denotes Thanks to the development of serological tests (Amanat et al., 2020, Cai et al., 2020, Xiang et al., 2020b, Zhang et al., 2020d), recovered COVID-19 patients can be screened to select plasma with high antibody titers.
T590 100788-101056 Sentence denotes Some studies and case reports on CP therapy for COVID-19 have evaluated the safety and the potential effectiveness of CP therapy in patients with severe disease (Ahn et al., 2020, Duan et al., 2020, Pei et al., 2020, Shen et al., 2020, Zhang et al., 2020b) (Table 4 ).
T591 101057-101219 Sentence denotes These studies were neither controlled nor randomized, but they suggest that CP therapy is safe and can have a beneficial effect on the clinical course of disease.
T592 101220-101319 Sentence denotes Further controlled trials are needed to determine the optimal timing and indication for CP therapy.
T593 101320-101499 Sentence denotes CP therapy has also been proposed for prophylactic use in at-risk individuals, such as those with underlying health conditions or health care workers exposed to COVID-19 patients.
T594 101500-101582 Sentence denotes The FDA has approved the use of CP to treat critically ill patients (Tanne, 2020).
T595 101583-101851 Sentence denotes Determining when to administer the CP is also of great importance, as a study in SARS-CoV-1 patients showed that CP was much more efficient when given to patients before day 14 day of illness (Cheng et al., 2005b), as previously shown in influenza (Luke et al., 2006).
T596 101852-101949 Sentence denotes This study also showed that CP therapy was more efficient in PCR-positive, seronegative patients.
T597 101950-102046 Sentence denotes The amount of plasma and number of transfusions needed requires further investigation (Table 4).
T598 102047-102123 Sentence denotes Table 4 Clinical Studies of Convalescent Plasma Therapy in COVID-19 Patients
T599 102124-102185 Sentence denotes Patient Characteristics Start of CP Therapy Results Reference
T600 102186-102341 Sentence denotes 5 severe patients (30–70 yo) between 10 and 22 days after hospital admission body temperature normalized within 3 days in 4 of 5 patients Shen et al., 2020
T601 102342-102362 Sentence denotes clinical improvement
T602 102363-102424 Sentence denotes viral loads became negative within 12 days of the transfusion
T603 102425-102445 Sentence denotes nAb titers increased
T604 102446-102553 Sentence denotes 10 severe patients (34–78 yo) median 16.5 dpo disappearance of clinical symptoms after 3d Duan et al., 2020
T605 102554-102571 Sentence denotes chest CT improved
T606 102572-102636 Sentence denotes elevation of lymphocyte counts in patients with lymphocytopenia.
T607 102637-102669 Sentence denotes increase in SaO2 in all patients
T608 102670-102716 Sentence denotes resolution of SARS-CoV-2 viremia in 7 patients
T609 102717-102771 Sentence denotes increase in neutralizing antibody titers in 5 patients
T610 102772-102918 Sentence denotes 4 critical patients (31–73 yo) at degradation of symptoms,between 11 and 19 days after hospital admission clinical improvement Zhang et al., 2020b
T611 102919-102937 Sentence denotes reduced viral load
T612 102938-102955 Sentence denotes chest CT improved
T613 102956-103068 Sentence denotes 1 moderate patient, 2 critical patients 12 dpo, 27 dpo viral detection negative 4 days after CP Pei et al., 2020
T614 103069-103103 Sentence denotes clinical improvement of 2 patients
T615 103104-103190 Sentence denotes 2 severe patients (67 and 71 yo) 7 dpo or 22 dpo clinical improvement Ahn et al., 2020
T616 103191-103209 Sentence denotes reduced viral load
T617 103210-103227 Sentence denotes chest CT improved
T618 103228-103276 Sentence denotes yo, years old; dpo, days post onset of symptoms.
T619 103277-103403 Sentence denotes Overall, CP therapy seems to be associated with improved outcomes and appears to be safe, but RCTs are needed to confirm this.
T620 103404-103487 Sentence denotes Several clinical trials are currently in progress worldwide (Belhadi et al., 2020).
T621 103489-103508 Sentence denotes Vaccine Development
T622 103509-103770 Sentence denotes The devastating effects of the pandemic spread of SARS-CoV-2 in a globally naive population has resulted in unprecedented efforts to rapidly develop, test, and disseminate a vaccine to protect against COVID-19 or to mitigate the effects of SARS-CoV-2 infection.
T623 103771-103952 Sentence denotes Although vaccination has a long and successful history as an effective global health strategy, there are currently no approved vaccines to protect humans against CoVs (André, 2003).
T624 103953-104161 Sentence denotes Previous work after the SARS-CoV-1 and MERS-CoV epidemics has provided a foundation on which many current efforts are currently building upon, including the importance of the S protein as a potential vaccine.
T625 104162-104350 Sentence denotes Diverse vaccine platforms and preclinical animal models have been adapted to SARS-CoV-2, facilitating fast-moving and robust progress in creating and testing SARS-CoV-2 vaccine candidates.
T626 104351-104487 Sentence denotes A number of vaccine candidates are already being tested in clinical trials, and more are continuing to progress toward clinical testing.
T627 104489-104522 Sentence denotes The S Protein as a Vaccine Target
T628 104523-104672 Sentence denotes Since SARS-CoV-1 first emerged, the S protein has been favored as the most promising target for vaccine development to protect against CoV infection.
T629 104673-104984 Sentence denotes This particular viral protein has important roles in viral entry and in stimulating the immune response during natural infection and in vaccination studies of both SARS-CoV-1 and MERS-CoV (Du et al., 2009, Song et al., 2019, Zhou et al., 2018), which has also been confirmed for SARS-CoV-2 (Walls et al., 2020).
T630 104985-105158 Sentence denotes The S protein has been found to induce robust and protective humoral and cellular immunity, including the development of nAbs and T cell-mediated immunity (Du et al., 2009).
T631 105159-105632 Sentence denotes In animal models, correlates of protection against SARS-CoV-1 infection appear to be induction of nAbs against the S protein, although antibodies to other proteins have been detected, such as those against nucleoprotein (N) and ORF3a (Qiu et al., 2005, Sui et al., 2005). nAbs are also believed to protect against infection by blocking receptor binding and viral entry, which has been shown with pseudovirus-based neutralization assays (Ni et al., 2020, Nie et al., 2020a).
T632 105633-106100 Sentence denotes Studies of SARS-CoV-1 indicate that T cell response against the S protein correlates with nAb titers and dominated the T cell response after natural infection, which also induced T cells active against the membrane (M) and N proteins, that memory T cell responses can persist even 11 years after infection, and that memory CD8+ T cells can protect mice from lethal challenge in the absence of memory CD4+ T cells and memory B cells (Li et al., 2008, Ng et al., 2016).
T633 106101-106298 Sentence denotes RBD-specific antiviral T cell responses have also been detected in people who have recovered from COVID-19, further validating its promise as a vaccine target (Braun et al., 2020, Ni et al., 2020).
T634 106300-106315 Sentence denotes Epitope Mapping
T635 106316-106568 Sentence denotes Although the antibodies targeting the RBD of the S protein have greater potential for providing cross-protective immunity, other fragments of the S protein and additional viral proteins have been investigated as target epitopes, especially for T cells.
T636 106569-107097 Sentence denotes Researchers have taken advantage of the genetic similarity between SARS-CoV-2 and SARS-CoV-1 and MERS-CoV and bioinformatics approaches to rapidly identify potential B and T cell epitopes in the S and other proteins, with many studies providing data regarding antigen presentation and antibody-binding properties and one study looking into the predicted evolution of epitopes (Ahmed et al., 2020, Baruah and Bose, 2020, Bhattacharya et al., 2020, Fast et al., 2020, Grifoni et al., 2020, Lon et al., 2020, Zheng and Song, 2020).
T637 107098-107329 Sentence denotes While the S protein has been found to be the most immunodominant protein in SARS-CoV-2, the M and N proteins also contain B and T cell epitopes, including some with high conservation with SARS-CoV-1 epitopes (Grifoni et al., 2020).
T638 107331-107347 Sentence denotes Vaccine Pipeline
T639 107348-107621 Sentence denotes For SARS-CoV-1 and MERS-CoV, animal studies and phase I clinical trials of potential vaccines targeting the S protein had encouraging results, with evidence of nAb induction and induction of cellular immunity (Lin et al., 2007, Martin et al., 2008, Modjarrad et al., 2019).
T640 107622-107738 Sentence denotes These findings are being translated into SARS-CoV-2 vaccine development efforts, hastening the progress drastically.
T641 107739-107898 Sentence denotes The WHO provided a report in April that reported 63 vaccine candidates in preclinical testing and three in clinical testing (World Health Organization, 2020b).
T642 107899-108005 Sentence denotes A recent search on May 1, 2020 on ClinicalTrials.gov revealed 10 registered vaccine candidates (Table 5 ).
T643 108006-108189 Sentence denotes The University of Pittsburgh is also looking to move their microneedle array vaccine candidate containing a codon-optimized S1 subunit protein into clinical trials (Kim et al., 2020).
T644 108190-108454 Sentence denotes Sanofi and GlaxoSmithKline (GSK) have recently reported their intent to collaborate and bring together Sanofi’s baculovirus expression system, which is used to produce the influenza virus vaccine, Flublok, to create an S protein vaccine adjuvanted with GSK’s AS03.
T645 108455-108655 Sentence denotes Sinovac Biotech will also enter testing in a clinical trial in China after it was found to protect rhesus macaques from viral challenge without signs of detectable immunopathology (Gao et al., 2020c).
T646 108656-108926 Sentence denotes Although some of these vaccine candidates are based on platforms that have been used or tested for other purposes, there remain questions regarding their safety and immunogenicity, including the longevity of any induced responses, that will require continual evaluation.
T647 108927-108994 Sentence denotes Table 5 Vaccine Candidates Currently Registered for Clinical Trials
T648 108995-109068 Sentence denotes Candidate Design Developer Similar Strategy ClinicalTrials.gov Identifier
T649 109069-109198 Sentence denotes mRNA-1273 LNP-encapsulated mRNA for full-length S protein ModernaTX CMV (John et al., 2018), ZKV (Pardi et al., 2017) NCT04283461
T650 109199-109380 Sentence denotes BNT162a1, b1, b2, c2 LNP-encapsulated mRNA vaccines with different formats of RNA and targets, two for larger S sequence and two for optimized RBD BioNTech SE and Pfizer NCT04368728
T651 109381-109524 Sentence denotes INO-4800 DNA vaccine for full-length S protein Inovio Pharmaceuticals MERS-CoV (Modjarrad et al., 2019), HPV (Trimble et al., 2015) NCT04336410
T652 109525-109685 Sentence denotes Ad5-nCoV adenovirus type 5 encoding full-length S protein CanSino Biologics EBV (Zhu et al., 2015, Zhu et al., 2017) NCT04313127 (phase I)NCT04341389 (phase II)
T653 109686-109837 Sentence denotes ChAdOx1 nCoV-19 adenovirus encoding full-length S protein University of Oxford MERS-CoV (Alharbi et al., 2017), IAV (Antrobus et al., 2014) NCT04324606
T654 109838-110036 Sentence denotes COVID-19 LV-SMENP-DC dendritic cells infected with lentivirus expressing SMENP minigenes to express COVID-19 antigens, together with activated CTLs Shenzhen Geno-Immune Medical Institute NCT04276896
T655 110037-110183 Sentence denotes COVID-19 aAPCs aAPCs infected with lentivirus expressing minigenes to express COVID-19 antigens Shenzhen Geno-Immune Medical Institute NCT04299724
T656 110184-110331 Sentence denotes bacTRL-Spike-1 live bacteria delivering plasmid encoding S protein Symvivo Corporation therapeutics reviewed (Charbonneau et al., 2020) NCT04334980
T657 110332-110439 Sentence denotes PiCoVacc inactivated SARS-CoV-2 vaccine Sinovac Biotech HAV, IAV, IBV, poliovirus, rabies virus NCT04352608
T658 110440-110542 Sentence denotes SARS-CoV-2 rS spike protein nanoparticle vaccine with or without Matrix-M adjuvant Novavax NCT04368988
T659 110543-110767 Sentence denotes aAPCs, artificial antigen-presenting cells; CMV, cytomegalovirus; EBV, Ebola virus; HAV, hepatitis A virus; HPV, human papillomavirus; IAV, influenza A virus; IBV, influenza B virus; LPN, lipid nanoparticle; ZKV, Zika virus.
T660 110769-110779 Sentence denotes Challenges
T661 110780-110985 Sentence denotes Although the development of a vaccine to protect against SARS-CoV-2 infection has progressed at an unprecedented rate and produced an impressive volume of candidates for testing, many challenges lie ahead.
T662 110986-111291 Sentence denotes The prior knowledge gained after SARS-CoV-1 was first discovered in 2003, and the subsequent emergence of MERS-CoV in 2012 provided a significant jumpstart, but the progress of SARS-CoV-2 vaccine development has already far outstripped the point of the blueprint created before COVID-19 became a pandemic.
T663 111292-111489 Sentence denotes While a variety of platforms are simultaneously being innovated or adapted, they each have strengths and limitations, many of which relate to the delicate balance between safety and immunogenicity.
T664 111490-111650 Sentence denotes Many shortcuts have been taken and will continue to be taken due to the urgency of the ongoing COVID-19 pandemic, but significant concerns need to be addressed.
T665 111651-111792 Sentence denotes One such concern involves the accumulating data supporting the initial assessment that COVID-19 is disproportionately severe in older adults.
T666 111793-112005 Sentence denotes In conjunction with the large body of work related to immune senescence, these findings indicate that vaccine design should take into consideration the impact of aging on vaccine efficacy (Nikolich-Žugich, 2018).
T667 112006-112283 Sentence denotes Furthermore, questions remain regarding the possibility of antibody-dependent enhancement of COVID-19, with in vitro experiments, animal studies, and two studies of COVID-19 patients supporting this possibility (Cao, 2020, Tetro, 2020, Zhang et al., 2020a, Zhao et al., 2020a).
T668 112284-112458 Sentence denotes Assuming vaccine candidates that can safely induce protective immune responses are identified, additional major hurdles will be the production and dissemination of a vaccine.
T669 112459-112757 Sentence denotes For some types of vaccines, large-scale production will not be as much of an issue, and infrastructure already in place to produce current Good Manufacturing Practice (cGMP)-quality biologics can be repurposed, but this will only be applicable to a subset of the candidates (Thanh Le et al., 2020).
T670 112758-113180 Sentence denotes In order to address the urgent need and stem the COVID-19 pandemic, regulatory agencies need to continue to support rapid testing and progression of vaccine candidates, companies need to disseminate important findings directly and openly, and researchers need to investigate correlates of protection using in-depth immune monitoring of patients with a broad range of clinical presentations and clinical trial participants.
T671 113181-113370 Sentence denotes The newly announced Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) is designed to bring together numerous governmental and industry entities to help address this need.
T672 113372-113390 Sentence denotes Concluding Remarks
T673 113391-113608 Sentence denotes The rapid spread of SARS-CoV-2 and the unprecedented nature of COVID-19 has demanded an urgency in both basic science and clinical research, and the scientific community has met that call with remarkable productivity.
T674 113609-113756 Sentence denotes Within months, there has been a significant generation of scientific knowledge that has shed some light on the immunology of SARS-CoV-2 infections.
T675 113757-113878 Sentence denotes Studies of past coronavirus outbreaks involving SARS-CoV-1 and MERS-CoV have provided a foundation for our understanding.
T676 113879-114021 Sentence denotes The pathology of severe cases of COVID-19 does indeed resemble certain immunopathologies seen in SARS-CoV-1 and MERS-CoV infections, like CRS.
T677 114022-114145 Sentence denotes However, in many other ways, immune responses to SARS-CoV-2 are distinct from those seen with other coronavirus infections.
T678 114146-114486 Sentence denotes The emerging epidemiological observation that significant proportions of individuals are asymptomatic despite infection not only reflects our current understanding that SARS-CoV-2 has a longer incubation period and higher rate of transmission than other coronaviruses, but also speaks to significant differences in the host immune response.
T679 114487-114685 Sentence denotes Therefore, it is imperative that immune responses against SARS-CoV-2 and mechanisms of hyperinflammation-driven pathology are further elucidated to better define therapeutic strategies for COVID-19.
T680 114686-115026 Sentence denotes Here, we reviewed the recent literature and highlighted hypotheses that interrogate mechanisms for viral escape from innate sensing, for hyperinflammation associated with CRS and inflammatory myeloid subpopulations, for lymphopenia marked by T cell and NK cell dysfunction, and for correlates of protection and their duration, among others.
T681 115027-115234 Sentence denotes Still, additional studies are needed to address how these immune differences across patients or between different types of coronavirus infections dictate who succumbs to disease and who remains asymptomatic.
T682 115235-115379 Sentence denotes Existing studies of SARS-CoV-1 and MERS-CoV and ongoing studies of SARS-CoV-2 will likely provide a robust framework to fulfill that unmet need.
T683 115381-115390 Sentence denotes Consortia
T684 115391-115614 Sentence denotes The members of the Sinai Immunology Review Project are Manasi Agrawal, Mark Aleynick, Meriem Belabed, Graham Britton, Matthew Brown, Maria Casanova-Acebes, Jovani Catalan, Monica Centa, Andrew Charap, Andrew Chan, Steven T.
T685 115615-116134 Sentence denotes Chen, Jonathan Chung, Cansu Cimen Bozkus, Evan Cody, Francesca Cossarini, Erica Dalla, Nicolas Fernandez, John Grout, Conor Gruber, Dan Fu Ruan, Pauline Hamon, Samarth Hegde, Etienne Humblin, Divya Jha, Maria Kuksin, Julia Kodysh, Andrew Leader, Rachel Levantovsky, Matthew Lin, Katherine Lindblad, Daniel Lozano-Ojalvo, Gabrielle Lubitz, Assaf Magen, Zafar Mahmood, Louise Malle, Gustavo Martinez-Delgado, Jaime Mateus-Tique, Elliot Meritt, Chang Moon, Alvaro Moreira, Justine Noel, Tim O’Donnell, Miyo Ota, Matthew D.
T686 116135-116251 Sentence denotes Park, Luisanna Pia, Tamar Plitt, Venu Pothula, Jamie Redes, Ivan Reyes Torres, Emma Risson, Mark Roberto, Alfonso R.
T687 116252-116466 Sentence denotes Sanchez-Paulete, Miriam Saffern, Bérengère Salomé, Myvizhi Esai Selvan, Joan Shang, Matthew Spindler, Alessandra Soares Schanoski, Maria Suprun, Jessica Tan, Michelle Tran, Verena van der Heide, Natalie Vaninov, C.
T688 116467-116628 Sentence denotes Matthias Wilk, Julio Aguirre-Ghiso, Konstantina Alexandropoulos, Nina Bhardwaj, Dusan Bogunovic, Brian Brown, Judy Cho, Jeremiah Faith, Emilie Grasset, Zeynep H.
T689 116629-116706 Sentence denotes Gümüş, Peter Heeger, Dirk Homann, Amir Horowitz, Ephraim Kenigsberg, Alice O.
T690 116707-116743 Sentence denotes Kamphorst, Florian Krammer, Maria A.
T691 116744-116847 Sentence denotes Curotto de Lafaille, Uri Laserson, Saurabh Mehandru, Miriam Merad, Robert Samstein, and Nicolas Vabret.
T692 116849-116864 Sentence denotes Acknowledgments
T693 116865-116947 Sentence denotes We apologize to all authors whose work we could not cite due to space limitations.
T694 116948-117051 Sentence denotes Trainee (PhD and MD/PhD or postdocs) and faculty contributing authors are listed in alphabetical order.
T695 117052-117080 Sentence denotes Illustrations are by Jill K.
T696 117081-117143 Sentence denotes Gregory and used with permission of Mount Sinai Health System.
T697 117144-117399 Sentence denotes We would like to acknowledge funding sources including Fastgrant (M.M.), NCI Cancer Center Support Grant Supplement (M.M., R.M.S.) Burroughs Wellcome Fund (R.M.S.), NIH Director’s Early Independence Award (R.M.S.) and NIH R01AI081848 (N.V., N.B., B.D.G.).
T698 117401-117425 Sentence denotes Declaration of Interests
T699 117426-117652 Sentence denotes N.B. serves as an advisor/board member for Neon, Checkpoint Sciences, Primevax, Novartis, Array BioPharma, Roche, Avidea, Boeringer Ingelheim, Rome Therapeutics, Roswell Park, and the Parker Institute for Cancer Immunotherapy.
T700 117653-117763 Sentence denotes N.B. receives research support from the Parker Insitute, Novocure, Celldex, Genentech, Oncovir, and Regeneron.
T701 117764-117883 Sentence denotes M.M. serves as an advisor/board member for Celsius, Pionyr, Compugen, Myeloids and Innate pharma and ad hoc for Takeda.
T702 117884-117953 Sentence denotes M.M. receives research support from Regeneron, Takeda, and Genentech.
T703 117954-118019 Sentence denotes A.M. has equity in Gilead Sciences and Regeneron Pharmaceuticals.