PMC:7199903 / 4682-4938
Annnotations
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T35 | 131-132 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T36 | 223-224 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T33 | 139-146 | Chemical | denotes | Gly-Ser | http://purl.obolibrary.org/obo/CHEBI_73516 |
T34 | 139-142 | Chemical | denotes | Gly | http://purl.obolibrary.org/obo/CHEBI_15428 |
T35 | 143-146 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
T37 | 147-154 | Chemical | denotes | Ala-Ser | http://purl.obolibrary.org/obo/CHEBI_73394 |
T38 | 147-150 | Chemical | denotes | Ala | http://purl.obolibrary.org/obo/CHEBI_16977|http://purl.obolibrary.org/obo/CHEBI_46217 |
T40 | 151-154 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T29 | 191-195 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T752 | 0-13 | NN | denotes | Stabilization |
T753 | 14-16 | IN | denotes | of |
T754 | 17-20 | DT | denotes | the |
T755 | 21-29 | JJ | denotes | trimeric |
T756 | 30-39 | NN | denotes | prefusion |
T757 | 40-49 | NN | denotes | structure |
T758 | 50-53 | VBD | denotes | was |
T759 | 54-62 | VBN | denotes | achieved |
T760 | 63-65 | IN | denotes | by |
T761 | 66-71 | VBG | denotes | using |
T762 | 72-75 | DT | denotes | the |
T763 | 76-78 | NN | denotes | 2P |
T764 | 79-90 | VBG | denotes | stabilizing |
T765 | 91-100 | NNS | denotes | mutations |
T766 | 101-102 | -LRB- | denotes | ( |
T767 | 102-104 | CD | denotes | 20 |
T768 | 104-105 | -RRB- | denotes | ) |
T769 | 106-108 | IN | denotes | at |
T770 | 109-117 | NNS | denotes | residues |
T771 | 118-121 | CD | denotes | 986 |
T772 | 122-125 | CC | denotes | and |
T773 | 126-129 | CD | denotes | 987 |
T774 | 129-130 | -COMMA- | denotes | , |
T775 | 131-132 | DT | denotes | a |
T776 | 133-137 | NN | denotes | GSAS |
T777 | 138-139 | -LRB- | denotes | ( |
T778 | 139-154 | NN | denotes | Gly-Ser-Ala-Ser |
T779 | 154-155 | -RRB- | denotes | ) |
T780 | 156-168 | NN | denotes | substitution |
T781 | 169-171 | IN | denotes | at |
T782 | 172-175 | DT | denotes | the |
T783 | 176-181 | NN | denotes | furin |
T784 | 182-190 | NN | denotes | cleavage |
T785 | 191-195 | NN | denotes | site |
T786 | 196-197 | -LRB- | denotes | ( |
T787 | 197-205 | NNS | denotes | residues |
T788 | 206-209 | CD | denotes | 682 |
T789 | 210-212 | TO | denotes | to |
T790 | 213-216 | CD | denotes | 685 |
T791 | 216-217 | -RRB- | denotes | ) |
T792 | 217-218 | -COMMA- | denotes | , |
T793 | 219-222 | CC | denotes | and |
T794 | 223-224 | DT | denotes | a |
T795 | 225-235 | JJ | denotes | C-terminal |
T796 | 236-249 | NN | denotes | trimerization |
T797 | 250-255 | NN | denotes | motif |
R756 | T752 | T753 | arg1Of | Stabilization,of |
R757 | T757 | T753 | arg2Of | structure,of |
R758 | T757 | T754 | arg1Of | structure,the |
R759 | T757 | T755 | arg1Of | structure,trimeric |
R760 | T757 | T756 | arg1Of | structure,prefusion |
R761 | T752 | T758 | arg1Of | Stabilization,was |
R762 | T759 | T758 | arg2Of | achieved,was |
R763 | T752 | T759 | arg2Of | Stabilization,achieved |
R764 | T759 | T760 | arg1Of | achieved,by |
R765 | T761 | T760 | arg2Of | using,by |
R766 | T765 | T761 | arg2Of | mutations,using |
R767 | T765 | T762 | arg1Of | mutations,the |
R768 | T765 | T763 | arg1Of | mutations,2P |
R769 | T765 | T764 | arg1Of | mutations,stabilizing |
R770 | T765 | T766 | arg1Of | mutations,( |
R771 | T767 | T766 | arg2Of | 20,( |
R772 | T768 | T766 | arg3Of | ),( |
R773 | T761 | T769 | arg1Of | using,at |
R774 | T793 | T769 | arg2Of | and,at |
R775 | T772 | T770 | arg1Of | and,residues |
R776 | T771 | T772 | arg1Of | 986,and |
R777 | T773 | T772 | arg2Of | 987,and |
R778 | T772 | T774 | arg1Of | and,"," |
R779 | T780 | T774 | arg2Of | substitution,"," |
R780 | T780 | T775 | arg1Of | substitution,a |
R781 | T780 | T776 | arg1Of | substitution,GSAS |
R782 | T780 | T777 | arg1Of | substitution,( |
R783 | T778 | T777 | arg2Of | Gly-Ser-Ala-Ser,( |
R784 | T779 | T777 | arg3Of | ),( |
R785 | T780 | T781 | arg1Of | substitution,at |
R786 | T785 | T781 | arg2Of | site,at |
R787 | T785 | T782 | arg1Of | site,the |
R788 | T785 | T783 | arg1Of | site,furin |
R789 | T785 | T784 | arg1Of | site,cleavage |
R790 | T785 | T786 | arg1Of | site,( |
R791 | T790 | T786 | arg2Of | 685,( |
R792 | T791 | T786 | arg3Of | ),( |
R793 | T790 | T787 | arg1Of | 685,residues |
R794 | T790 | T788 | arg1Of | 685,682 |
R795 | T790 | T789 | arg1Of | 685,to |
R796 | T793 | T792 | arg1Of | and,"," |
R797 | T772 | T793 | arg1Of | and,and |
R798 | T797 | T793 | arg2Of | motif,and |
R799 | T797 | T794 | arg1Of | motif,a |
R800 | T797 | T795 | arg1Of | motif,C-terminal |
R801 | T797 | T796 | arg1Of | motif,trimerization |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T27 | 139-150 | Chemical | denotes | Gly-Ser-Ala | http://purl.obolibrary.org/obo/CHEBI_163987 |
T28 | 151-154 | Chemical | denotes | Ser | http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_29999 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T35 | 0-256 | Sentence | denotes | Stabilization of the trimeric prefusion structure was achieved by using the 2P stabilizing mutations (20) at residues 986 and 987, a GSAS (Gly-Ser-Ala-Ser) substitution at the furin cleavage site (residues 682 to 685), and a C-terminal trimerization motif. |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
147 | 139-154 | Chemical | denotes | Gly-Ser-Ala-Ser |
149 | 133-137 | CellLine | denotes | GSAS |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T402 | 176-181 | Protein | denotes | furin | https://www.uniprot.org/uniprot/Q9UCZ5|https://www.uniprot.org/uniprot/Q6LBS3|https://www.uniprot.org/uniprot/Q6GTN6|https://www.uniprot.org/uniprot/Q28193|https://www.uniprot.org/uniprot/Q14336|https://www.uniprot.org/uniprot/P23377|https://www.uniprot.org/uniprot/P23188|https://www.uniprot.org/uniprot/P09958 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T35 | 0-256 | Sentence | denotes | Stabilization of the trimeric prefusion structure was achieved by using the 2P stabilizing mutations (20) at residues 986 and 987, a GSAS (Gly-Ser-Ala-Ser) substitution at the furin cleavage site (residues 682 to 685), and a C-terminal trimerization motif. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
147 | 139-154 | Chemical | denotes | Gly-Ser-Ala-Ser |
149 | 133-137 | CellLine | denotes | GSAS |