PMC:7199903 / 14195-15028
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T5 | 97-104 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
T6 | 170-177 | https://glytoucan.org/Structures/Glycans/G70323CJ | denotes | mannose |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T75 | 68-71 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T76 | 97-104 | Body_part | denotes | mannose | http://purl.org/sig/ont/fma/fma82801 |
T77 | 130-137 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T78 | 170-177 | Body_part | denotes | mannose | http://purl.org/sig/ont/fma/fma82801 |
T79 | 361-369 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T50 | 334-342 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T51 | 348-356 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T52 | 461-469 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T85 | 115-117 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T86 | 223-225 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T87 | 283-291 | http://purl.obolibrary.org/obo/CLO_0009898 | denotes | (10), no |
T88 | 308-311 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T147 | 97-104 | Chemical | denotes | mannose | http://purl.obolibrary.org/obo/CHEBI_37684 |
T148 | 130-137 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T149 | 170-177 | Chemical | denotes | mannose | http://purl.obolibrary.org/obo/CHEBI_37684 |
T150 | 361-369 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T151 | 729-731 | Chemical | denotes | S4 | http://purl.obolibrary.org/obo/CHEBI_29401 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T64 | 375-379 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | site |
T65 | 706-711 | http://purl.obolibrary.org/obo/BFO_0000029 | denotes | sites |
LitCovid-sample-Enju
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9240 | 0-6 | RB | denotes | Highly |
T26423 | 7-12 | JJ | denotes | dense |
T31010 | 13-19 | NN | denotes | glycan |
T61332 | 20-27 | NNS | denotes | shields |
T42569 | 27-28 | -COMMA- | denotes | , |
T84675 | 29-33 | JJ | denotes | such |
T66981 | 34-36 | IN | denotes | as |
T81523 | 37-42 | DT | denotes | those |
T87200 | 43-51 | VBN | denotes | observed |
T40154 | 52-54 | IN | denotes | on |
T65532 | 55-59 | NN | denotes | LASV |
T5772 | 60-63 | NN | denotes | GPC |
T67488 | 64-67 | CC | denotes | and |
T10699 | 68-73 | NN | denotes | HIV-1 |
T62172 | 74-77 | NNP | denotes | Env |
T90671 | 77-78 | -COMMA- | denotes | , |
T16287 | 79-86 | VBP | denotes | feature |
T48112 | 87-96 | JJ | denotes | so-called |
T32762 | 97-104 | NN | denotes | mannose |
T70291 | 105-113 | NNS | denotes | clusters |
T21137 | 114-115 | -LRB- | denotes | ( |
T80604 | 115-117 | CD | denotes | 22 |
T6972 | 117-118 | -COMMA- | denotes | , |
T79738 | 119-121 | CD | denotes | 24 |
T38967 | 121-122 | -RRB- | denotes | ) |
T98752 | 123-125 | IN | denotes | on |
T93512 | 126-129 | DT | denotes | the |
T39612 | 130-137 | NN | denotes | protein |
T9646 | 138-145 | NN | denotes | surface |
T50448 | 146-147 | -LRB- | denotes | ( |
T81826 | 147-151 | NN | denotes | Fig. |
T39766 | 152-153 | CD | denotes | 4 |
T89772 | 153-154 | -RRB- | denotes | ) |
T66450 | 156-163 | IN | denotes | Whereas |
T54192 | 164-169 | JJ | denotes | small |
T75704 | 170-182 | JJ | denotes | mannose-type |
T64679 | 183-191 | NNS | denotes | clusters |
T67961 | 192-196 | VBP | denotes | have |
T50872 | 197-201 | VBN | denotes | been |
T72397 | 202-215 | VBN | denotes | characterized |
T86083 | 216-218 | IN | denotes | on |
T19628 | 219-222 | DT | denotes | the |
T60379 | 223-225 | NN | denotes | S1 |
T95927 | 226-233 | NN | denotes | subunit |
T61088 | 234-236 | IN | denotes | of |
T88650 | 237-243 | NNP | denotes | Middle |
T77913 | 244-248 | NNP | denotes | East |
T59650 | 249-260 | JJ | denotes | respiratory |
T56889 | 261-269 | NN | denotes | syndrome |
T75209 | 270-271 | -LRB- | denotes | ( |
T65502 | 271-275 | NNS | denotes | MERS |
T47025 | 275-276 | -RRB- | denotes | ) |
T38619 | 276-280 | NN | denotes | –CoV |
T85027 | 281-282 | NN | denotes | S |
T41284 | 283-284 | -LRB- | denotes | ( |
T20092 | 284-286 | CD | denotes | 10 |
T67731 | 286-287 | -RRB- | denotes | ) |
T60447 | 287-288 | -COMMA- | denotes | , |
T26837 | 289-291 | DT | denotes | no |
T36825 | 292-296 | JJ | denotes | such |
T21633 | 297-307 | NN | denotes | phenomenon |
T72717 | 308-311 | VBZ | denotes | has |
T43289 | 312-316 | VBN | denotes | been |
T51132 | 317-325 | VBN | denotes | observed |
T85295 | 326-329 | IN | denotes | for |
T9791 | 330-333 | DT | denotes | the |
T26717 | 334-344 | NN | denotes | SARS-CoV-1 |
T27044 | 345-347 | CC | denotes | or |
T2105 | 348-358 | NN | denotes | SARS-CoV-2 |
T82926 | 359-360 | NN | denotes | S |
T59746 | 361-369 | NNS | denotes | proteins |
T75148 | 371-374 | DT | denotes | The |
T54305 | 375-388 | JJ | denotes | site-specific |
T98072 | 389-402 | NN | denotes | glycosylation |
T89974 | 403-411 | NN | denotes | analysis |
T24686 | 412-420 | VBN | denotes | reported |
T87402 | 421-425 | RB | denotes | here |
T6472 | 426-434 | VBZ | denotes | suggests |
T51130 | 435-439 | IN | denotes | that |
T65358 | 440-443 | DT | denotes | the |
T44449 | 444-450 | NN | denotes | glycan |
T74101 | 451-457 | NN | denotes | shield |
T43467 | 458-460 | IN | denotes | of |
T56834 | 461-471 | NN | denotes | SARS-CoV-2 |
T19380 | 472-473 | NN | denotes | S |
T58633 | 474-476 | VBZ | denotes | is |
T93230 | 477-487 | JJ | denotes | consistent |
T34762 | 488-492 | IN | denotes | with |
T40649 | 493-498 | JJ | denotes | other |
T26331 | 499-512 | NNS | denotes | coronaviruses |
T79087 | 513-516 | CC | denotes | and |
T88865 | 517-526 | RB | denotes | similarly |
T45562 | 527-535 | VBZ | denotes | exhibits |
T4794 | 536-544 | JJ | denotes | numerous |
T90262 | 545-560 | NNS | denotes | vulnerabilities |
T96677 | 561-571 | IN | denotes | throughout |
T25127 | 572-575 | DT | denotes | the |
T33100 | 576-582 | NN | denotes | glycan |
T82801 | 583-589 | NN | denotes | shield |
T15404 | 590-591 | -LRB- | denotes | ( |
T44325 | 591-593 | CD | denotes | 10 |
T22249 | 593-594 | -RRB- | denotes | ) |
T88430 | 596-600 | JJ | denotes | Last |
T44884 | 600-601 | -COMMA- | denotes | , |
T47301 | 602-604 | PRP | denotes | we |
T38431 | 605-613 | VBD | denotes | detected |
T93001 | 614-619 | NN | denotes | trace |
T59318 | 620-626 | NNS | denotes | levels |
T23777 | 627-629 | IN | denotes | of |
T97663 | 630-638 | JJ | denotes | O-linked |
T9150 | 639-652 | NN | denotes | glycosylation |
T9101 | 653-655 | IN | denotes | at |
T19875 | 656-669 | NN | denotes | Thr323/Ser325 |
T53360 | 670-671 | -LRB- | denotes | ( |
T44595 | 671-680 | NN | denotes | T323/S325 |
T76708 | 680-681 | -RRB- | denotes | ) |
T47554 | 681-682 | -COMMA- | denotes | , |
T13997 | 683-687 | IN | denotes | with |
T37628 | 688-692 | IN | denotes | over |
T46382 | 693-695 | CD | denotes | 99 |
T30911 | 695-696 | NN | denotes | % |
T73157 | 697-699 | IN | denotes | of |
T21636 | 700-705 | DT | denotes | these |
T17607 | 706-711 | NNS | denotes | sites |
T16530 | 712-722 | JJ | denotes | unmodified |
T31888 | 723-724 | -LRB- | denotes | ( |
T21233 | 724-727 | NN | denotes | fig |
T31805 | 729-731 | NN | denotes | S4 |
T7918 | 731-732 | -RRB- | denotes | ) |
T49699 | 732-733 | -COMMA- | denotes | , |
T4878 | 734-744 | VBG | denotes | suggesting |
T67436 | 745-749 | IN | denotes | that |
T16574 | 750-758 | JJ | denotes | O-linked |
T4862 | 759-772 | NN | denotes | glycosylation |
T34118 | 773-775 | IN | denotes | of |
T78710 | 776-780 | DT | denotes | this |
T91351 | 781-787 | NN | denotes | region |
T67334 | 788-790 | VBZ | denotes | is |
T6257 | 791-798 | JJ | denotes | minimal |
T27983 | 799-803 | WRB | denotes | when |
T10765 | 804-807 | DT | denotes | the |
T94953 | 808-817 | NN | denotes | structure |
T41179 | 818-820 | VBZ | denotes | is |
T51038 | 821-832 | JJ | denotes | native-like |
R20228 | T26423 | T9240 | arg1Of | dense,Highly |
R89571 | T61332 | T26423 | arg1Of | shields,dense |
R48524 | T61332 | T31010 | arg1Of | shields,glycan |
R10199 | T61332 | T42569 | arg1Of | shields,"," |
R55975 | T66981 | T84675 | arg1Of | as,such |
R11072 | T61332 | T66981 | arg1Of | shields,as |
R30354 | T81523 | T66981 | arg2Of | those,as |
R64074 | T81523 | T87200 | arg2Of | those,observed |
R29515 | T87200 | T40154 | arg1Of | observed,on |
R79085 | T67488 | T40154 | arg2Of | and,on |
R75808 | T64679 | T72397 | arg2Of | clusters,characterized |
R34980 | T72397 | T86083 | arg1Of | characterized,on |
R12505 | T85027 | T86083 | arg2Of | S,on |
R31920 | T95927 | T19628 | arg1Of | subunit,the |
R17894 | T95927 | T60379 | arg1Of | subunit,S1 |
R83295 | T85027 | T95927 | arg1Of | S,subunit |
R93169 | T95927 | T61088 | arg1Of | subunit,of |
R95196 | T94953 | T41179 | arg1Of | structure,is |
R82269 | T51038 | T41179 | arg2Of | native-like,is |
R74655 | T94953 | T51038 | arg1Of | structure,native-like |
R42147 | T5772 | T65532 | arg1Of | GPC,LASV |
R6582 | T5772 | T67488 | arg1Of | GPC,and |
R73752 | T62172 | T67488 | arg2Of | Env,and |
R24467 | T62172 | T10699 | arg1Of | Env,HIV-1 |
R69077 | T16287 | T90671 | arg1Of | feature,"," |
R66046 | T61332 | T16287 | arg1Of | shields,feature |
R19719 | T70291 | T16287 | arg2Of | clusters,feature |
R41011 | T70291 | T48112 | arg1Of | clusters,so-called |
R18378 | T70291 | T32762 | arg1Of | clusters,mannose |
R99903 | T70291 | T21137 | arg1Of | clusters,( |
R11154 | T80604 | T21137 | arg2Of | 22,( |
R66208 | T38967 | T21137 | arg3Of | ),( |
R94435 | T80604 | T6972 | arg1Of | 22,"," |
R87842 | T79738 | T6972 | arg2Of | 24,"," |
R17882 | T70291 | T98752 | arg1Of | clusters,on |
R81137 | T9646 | T98752 | arg2Of | surface,on |
R91199 | T9646 | T93512 | arg1Of | surface,the |
R54507 | T9646 | T39612 | arg1Of | surface,protein |
R73293 | T70291 | T50448 | arg1Of | clusters,( |
R98958 | T81826 | T50448 | arg2Of | Fig.,( |
R84320 | T89772 | T50448 | arg3Of | ),( |
R56628 | T81826 | T39766 | arg1Of | Fig.,4 |
R49323 | T51132 | T66450 | arg1Of | observed,Whereas |
R56483 | T72397 | T66450 | arg2Of | characterized,Whereas |
R28990 | T64679 | T54192 | arg1Of | clusters,small |
R60142 | T64679 | T75704 | arg1Of | clusters,mannose-type |
R43003 | T64679 | T67961 | arg1Of | clusters,have |
R97960 | T72397 | T67961 | arg2Of | characterized,have |
R5307 | T64679 | T50872 | arg1Of | clusters,been |
R78469 | T72397 | T50872 | arg2Of | characterized,been |
R57246 | T56889 | T61088 | arg2Of | syndrome,of |
R69324 | T77913 | T88650 | arg1Of | East,Middle |
R44960 | T56889 | T77913 | arg1Of | syndrome,East |
R81536 | T56889 | T59650 | arg1Of | syndrome,respiratory |
R20253 | T56889 | T75209 | arg1Of | syndrome,( |
R22259 | T65502 | T75209 | arg2Of | MERS,( |
R7632 | T47025 | T75209 | arg3Of | ),( |
R94528 | T85027 | T38619 | arg1Of | S,–CoV |
R62994 | T85027 | T41284 | arg1Of | S,( |
R74989 | T20092 | T41284 | arg2Of | 10,( |
R55359 | T67731 | T41284 | arg3Of | ),( |
R41904 | T51132 | T60447 | arg1Of | observed,"," |
R56659 | T21633 | T26837 | arg1Of | phenomenon,no |
R62328 | T21633 | T36825 | arg1Of | phenomenon,such |
R85946 | T21633 | T72717 | arg1Of | phenomenon,has |
R30106 | T51132 | T72717 | arg2Of | observed,has |
R52908 | T21633 | T43289 | arg1Of | phenomenon,been |
R69651 | T51132 | T43289 | arg2Of | observed,been |
R93533 | T21633 | T51132 | arg2Of | phenomenon,observed |
R12880 | T51132 | T85295 | arg1Of | observed,for |
R70010 | T59746 | T85295 | arg2Of | proteins,for |
R26917 | T59746 | T9791 | arg1Of | proteins,the |
R29046 | T59746 | T26717 | arg1Of | proteins,SARS-CoV-1 |
R56504 | T26717 | T27044 | arg1Of | SARS-CoV-1,or |
R84605 | T2105 | T27044 | arg2Of | SARS-CoV-2,or |
R66137 | T59746 | T2105 | arg1Of | proteins,SARS-CoV-2 |
R81470 | T59746 | T82926 | arg1Of | proteins,S |
R84760 | T89974 | T75148 | arg1Of | analysis,The |
R7558 | T89974 | T54305 | arg1Of | analysis,site-specific |
R47845 | T89974 | T98072 | arg1Of | analysis,glycosylation |
R7666 | T89974 | T24686 | arg2Of | analysis,reported |
R97902 | T24686 | T87402 | arg1Of | reported,here |
R14856 | T89974 | T6472 | arg1Of | analysis,suggests |
R49382 | T79087 | T6472 | arg2Of | and,suggests |
R78090 | T79087 | T51130 | arg1Of | and,that |
R49422 | T74101 | T65358 | arg1Of | shield,the |
R86560 | T74101 | T44449 | arg1Of | shield,glycan |
R83796 | T74101 | T43467 | arg1Of | shield,of |
R71873 | T19380 | T43467 | arg2Of | S,of |
R26923 | T19380 | T56834 | arg1Of | S,SARS-CoV-2 |
R85308 | T74101 | T58633 | arg1Of | shield,is |
R88183 | T93230 | T58633 | arg2Of | consistent,is |
R36571 | T74101 | T93230 | arg1Of | shield,consistent |
R21390 | T93230 | T34762 | arg1Of | consistent,with |
R14625 | T26331 | T34762 | arg2Of | coronaviruses,with |
R68158 | T26331 | T40649 | arg1Of | coronaviruses,other |
R65894 | T58633 | T79087 | arg1Of | is,and |
R28494 | T45562 | T79087 | arg2Of | exhibits,and |
R44911 | T45562 | T88865 | arg1Of | exhibits,similarly |
R16891 | T74101 | T45562 | arg1Of | shield,exhibits |
R16721 | T90262 | T45562 | arg2Of | vulnerabilities,exhibits |
R81091 | T90262 | T4794 | arg1Of | vulnerabilities,numerous |
R86637 | T45562 | T96677 | arg1Of | exhibits,throughout |
R33795 | T82801 | T96677 | arg2Of | shield,throughout |
R12664 | T82801 | T25127 | arg1Of | shield,the |
R15185 | T82801 | T33100 | arg1Of | shield,glycan |
R40826 | T82801 | T15404 | arg1Of | shield,( |
R19439 | T44325 | T15404 | arg2Of | 10,( |
R29787 | T22249 | T15404 | arg3Of | ),( |
R72604 | T38431 | T44884 | arg1Of | detected,"," |
R36737 | T47301 | T38431 | arg1Of | we,detected |
R91862 | T59318 | T38431 | arg2Of | levels,detected |
R66682 | T30911 | T38431 | arg3Of | %,detected |
R72049 | T59318 | T93001 | arg1Of | levels,trace |
R25464 | T59318 | T23777 | arg1Of | levels,of |
R22871 | T9150 | T23777 | arg2Of | glycosylation,of |
R61644 | T9150 | T97663 | arg1Of | glycosylation,O-linked |
R40310 | T59318 | T9101 | arg1Of | levels,at |
R41989 | T19875 | T9101 | arg2Of | Thr323/Ser325,at |
R77433 | T19875 | T53360 | arg1Of | Thr323/Ser325,( |
R69441 | T44595 | T53360 | arg2Of | T323/S325,( |
R23420 | T76708 | T53360 | arg3Of | ),( |
R76302 | T38431 | T47554 | arg1Of | detected,"," |
R77591 | T38431 | T13997 | arg1Of | detected,with |
R95083 | T88430 | T13997 | arg2Of | Last,with |
R91853 | T46382 | T37628 | arg1Of | 99,over |
R33866 | T30911 | T46382 | arg1Of | %,99 |
R21894 | T30911 | T73157 | arg1Of | %,of |
R4541 | T17607 | T73157 | arg2Of | sites,of |
R82019 | T17607 | T21636 | arg1Of | sites,these |
R92566 | T17607 | T16530 | arg2Of | sites,unmodified |
R10683 | T21233 | T16530 | arg3Of | fig,unmodified |
R45734 | T21233 | T31888 | arg1Of | fig,( |
R6800 | T31805 | T7918 | arg1Of | S4,) |
R86766 | T31805 | T49699 | arg1Of | S4,"," |
R44057 | T4878 | T49699 | arg2Of | suggesting,"," |
R44722 | T67334 | T4878 | arg2Of | is,suggesting |
R70963 | T67334 | T67436 | arg1Of | is,that |
R97197 | T4862 | T16574 | arg1Of | glycosylation,O-linked |
R35289 | T4862 | T34118 | arg1Of | glycosylation,of |
R25284 | T91351 | T34118 | arg2Of | region,of |
R27170 | T91351 | T78710 | arg1Of | region,this |
R8903 | T4862 | T67334 | arg1Of | glycosylation,is |
R87998 | T6257 | T67334 | arg2Of | minimal,is |
R99688 | T4862 | T6257 | arg1Of | glycosylation,minimal |
R72243 | T67334 | T27983 | arg1Of | is,when |
R95180 | T41179 | T27983 | arg2Of | is,when |
R32829 | T94953 | T10765 | arg1Of | structure,the |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T77 | 170-177 | Body_part | denotes | mannose | http://purl.org/sig/ont/fma/fma82801 |
T78 | 361-369 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T74 | 68-71 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T75 | 97-104 | Body_part | denotes | mannose | http://purl.org/sig/ont/fma/fma82801 |
T76 | 130-137 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T112 | 97-104 | Chemical | denotes | mannose | http://purl.obolibrary.org/obo/CHEBI_37684 |
T113 | 130-137 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T114 | 170-177 | Chemical | denotes | mannose | http://purl.obolibrary.org/obo/CHEBI_37684 |
T115 | 361-369 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T55 | 55-59 | Species | denotes | LASV | NCBItxid:11620 |
T56 | 68-73 | Species | denotes | HIV-1 | NCBItxid:11676 |
T57 | 271-275 | Species | denotes | MERS | NCBItxid:1335626 |
T58 | 334-342 | Species | denotes | SARS-CoV | NCBItxid:694009 |
T59 | 348-358 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
T60 | 461-471 | Species | denotes | SARS-CoV-2 | NCBItxid:2697049 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T93 | 0-155 | Sentence | denotes | Highly dense glycan shields, such as those observed on LASV GPC and HIV-1 Env, feature so-called mannose clusters (22, 24) on the protein surface (Fig. 4). |
T94 | 156-370 | Sentence | denotes | Whereas small mannose-type clusters have been characterized on the S1 subunit of Middle East respiratory syndrome (MERS)–CoV S (10), no such phenomenon has been observed for the SARS-CoV-1 or SARS-CoV-2 S proteins. |
T95 | 371-595 | Sentence | denotes | The site-specific glycosylation analysis reported here suggests that the glycan shield of SARS-CoV-2 S is consistent with other coronaviruses and similarly exhibits numerous vulnerabilities throughout the glycan shield (10). |
T96 | 596-833 | Sentence | denotes | Last, we detected trace levels of O-linked glycosylation at Thr323/Ser325 (T323/S325), with over 99% of these sites unmodified (fig. S4), suggesting that O-linked glycosylation of this region is minimal when the structure is native-like. |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T44 | 334-342 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T45 | 348-358 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T46 | 461-471 | Disease | denotes | SARS-CoV-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
489 | 74-77 | Gene | denotes | Env | Gene:100616444 |
490 | 60-63 | Gene | denotes | GPC | Gene:2995 |
491 | 472-473 | Gene | denotes | S | Gene:43740568 |
492 | 359-360 | Gene | denotes | S | Gene:43740568 |
493 | 68-73 | Species | denotes | HIV-1 | Tax:11676 |
494 | 271-280 | Species | denotes | MERS)–CoV | Tax:1335626 |
495 | 334-342 | Species | denotes | SARS-CoV | Tax:694009 |
496 | 348-358 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
497 | 461-471 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
498 | 499-512 | Species | denotes | coronaviruses | Tax:11118 |
499 | 55-59 | Species | denotes | LASV | Tax:11620 |
500 | 13-19 | Chemical | denotes | glycan | MESH:D011134 |
501 | 97-104 | Chemical | denotes | mannose | MESH:D008358 |
502 | 170-177 | Chemical | denotes | mannose | MESH:D008358 |
503 | 444-450 | Chemical | denotes | glycan | MESH:D011134 |
504 | 576-582 | Chemical | denotes | glycan | MESH:D011134 |
505 | 656-662 | Chemical | denotes | Thr323 | |
506 | 663-669 | Chemical | denotes | Ser325 | |
507 | 237-269 | Disease | denotes | Middle East respiratory syndrome | MESH:D018352 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T2324 | 60-63 | Protein | denotes | GPC | https://www.uniprot.org/uniprot/P03711 |
T2325 | 74-77 | Protein | denotes | Env | https://www.uniprot.org/uniprot/C1JJY3 |
T2326 | 359-369 | Protein | denotes | S proteins | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
LitCovid-sample-PD-GO-BP-0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T37 | 389-402 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T38 | 639-652 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T39 | 759-772 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sample-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T35 | 389-402 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T36 | 639-652 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T37 | 759-772 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T41 | 389-402 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T42 | 630-652 | http://purl.obolibrary.org/obo/GO_0006493 | denotes | O-linked glycosylation |
T43 | 639-652 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T44 | 750-772 | http://purl.obolibrary.org/obo/GO_0006493 | denotes | O-linked glycosylation |
T45 | 759-772 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
LitCovid-sample-Glycan
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T81 | 97-104 | http://rdf.glyconavi.org/CarTNa/CarTNa218/trivialname | denotes | mannose |
T82 | 170-177 | http://rdf.glyconavi.org/CarTNa/CarTNa218/trivialname | denotes | mannose |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T93 | 0-155 | Sentence | denotes | Highly dense glycan shields, such as those observed on LASV GPC and HIV-1 Env, feature so-called mannose clusters (22, 24) on the protein surface (Fig. 4). |
T94 | 156-370 | Sentence | denotes | Whereas small mannose-type clusters have been characterized on the S1 subunit of Middle East respiratory syndrome (MERS)–CoV S (10), no such phenomenon has been observed for the SARS-CoV-1 or SARS-CoV-2 S proteins. |
T95 | 371-595 | Sentence | denotes | The site-specific glycosylation analysis reported here suggests that the glycan shield of SARS-CoV-2 S is consistent with other coronaviruses and similarly exhibits numerous vulnerabilities throughout the glycan shield (10). |
T96 | 596-833 | Sentence | denotes | Last, we detected trace levels of O-linked glycosylation at Thr323/Ser325 (T323/S325), with over 99% of these sites unmodified (fig. S4), suggesting that O-linked glycosylation of this region is minimal when the structure is native-like. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
489 | 74-77 | Gene | denotes | Env | Gene:100616444 |
490 | 60-63 | Gene | denotes | GPC | Gene:2995 |
491 | 472-473 | Gene | denotes | S | Gene:43740568 |
492 | 359-360 | Gene | denotes | S | Gene:43740568 |
493 | 68-73 | Species | denotes | HIV-1 | Tax:11676 |
494 | 271-280 | Species | denotes | MERS)–CoV | Tax:1335626 |
495 | 334-342 | Species | denotes | SARS-CoV | Tax:694009 |
496 | 348-358 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
497 | 461-471 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
498 | 499-512 | Species | denotes | coronaviruses | Tax:11118 |
499 | 55-59 | Species | denotes | LASV | Tax:11620 |
500 | 13-19 | Chemical | denotes | glycan | MESH:D011134 |
501 | 97-104 | Chemical | denotes | mannose | MESH:D008358 |
502 | 170-177 | Chemical | denotes | mannose | MESH:D008358 |
503 | 444-450 | Chemical | denotes | glycan | MESH:D011134 |
504 | 576-582 | Chemical | denotes | glycan | MESH:D011134 |
505 | 656-662 | Chemical | denotes | Thr323 | |
506 | 663-669 | Chemical | denotes | Ser325 | |
507 | 237-269 | Disease | denotes | Middle East respiratory syndrome | MESH:D018352 |