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{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7196351","sourcedb":"PMC","sourceid":"7196351","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7196351","text":"Besides, Cu is required for plant growth and development by regulating biological processes including catalyzing redox reactions, the photosynthetic and respiratory electron transport chain and ATP synthesis (19, 20), therefore Cu influences plant morphological and physiological responses such as seed germination, plant height, grain yield and mineral nutrients (19, 21). In addition, Cu exerts plant antifungal effect by inducing antioxidant/defensive enzyme activity in different plant species including maize (22) and tomato (21). A study by Adrees et al. reported that addition of Cu at concentration below 5 mg/kg dry weight (DW) shows a reduction in plant growth (19). In contrast, excessive Cu content also causes impairment of plant metabolic functions including enhanced generation of reactive oxygen species (ROS), oxidative damages and genetic mutations (19). Moreover, excessive Cu contributes to plant tolerance by inducing an increased expression of enzymes against ROS and binding of this metal to plant cell wall to stimulate secretion of toxins (20). The maximum permissible level of Cu for plant nutrition is different from one to another and depends on the growth stage of plants (20). Recent studies on metal nanoparticles have shown that nCu is to facilitate the absorption of water from extracellular matrix (23), leading to an enhanced synthesis of nutrients by passive protein channels/pumps in plants.","tracks":[{"project":"2_test","denotations":[{"id":"32373300-25874438-54158459","span":{"begin":209,"end":211},"obj":"25874438"},{"id":"32373300-27968998-54158460","span":{"begin":213,"end":215},"obj":"27968998"},{"id":"32373300-25874438-54158461","span":{"begin":365,"end":367},"obj":"25874438"},{"id":"32373300-25617841-54158462","span":{"begin":369,"end":371},"obj":"25617841"},{"id":"32373300-28851884-54158463","span":{"begin":515,"end":517},"obj":"28851884"},{"id":"32373300-25617841-54158464","span":{"begin":531,"end":533},"obj":"25617841"},{"id":"32373300-25874438-54158465","span":{"begin":672,"end":674},"obj":"25874438"},{"id":"32373300-25874438-54158466","span":{"begin":868,"end":870},"obj":"25874438"},{"id":"32373300-27968998-54158467","span":{"begin":1065,"end":1067},"obj":"27968998"},{"id":"32373300-27968998-54158468","span":{"begin":1202,"end":1204},"obj":"27968998"},{"id":"T10901","span":{"begin":209,"end":211},"obj":"25874438"},{"id":"T38919","span":{"begin":213,"end":215},"obj":"27968998"},{"id":"T39406","span":{"begin":365,"end":367},"obj":"25874438"},{"id":"T87981","span":{"begin":369,"end":371},"obj":"25617841"},{"id":"T50318","span":{"begin":515,"end":517},"obj":"28851884"},{"id":"T55329","span":{"begin":531,"end":533},"obj":"25617841"},{"id":"T44045","span":{"begin":672,"end":674},"obj":"25874438"},{"id":"T65284","span":{"begin":868,"end":870},"obj":"25874438"},{"id":"T43819","span":{"begin":1065,"end":1067},"obj":"27968998"},{"id":"T57689","span":{"begin":1202,"end":1204},"obj":"27968998"}],"attributes":[{"subj":"32373300-25874438-54158459","pred":"source","obj":"2_test"},{"subj":"32373300-27968998-54158460","pred":"source","obj":"2_test"},{"subj":"32373300-25874438-54158461","pred":"source","obj":"2_test"},{"subj":"32373300-25617841-54158462","pred":"source","obj":"2_test"},{"subj":"32373300-28851884-54158463","pred":"source","obj":"2_test"},{"subj":"32373300-25617841-54158464","pred":"source","obj":"2_test"},{"subj":"32373300-25874438-54158465","pred":"source","obj":"2_test"},{"subj":"32373300-25874438-54158466","pred":"source","obj":"2_test"},{"subj":"32373300-27968998-54158467","pred":"source","obj":"2_test"},{"subj":"32373300-27968998-54158468","pred":"source","obj":"2_test"},{"subj":"T10901","pred":"source","obj":"2_test"},{"subj":"T38919","pred":"source","obj":"2_test"},{"subj":"T39406","pred":"source","obj":"2_test"},{"subj":"T87981","pred":"source","obj":"2_test"},{"subj":"T50318","pred":"source","obj":"2_test"},{"subj":"T55329","pred":"source","obj":"2_test"},{"subj":"T44045","pred":"source","obj":"2_test"},{"subj":"T65284","pred":"source","obj":"2_test"},{"subj":"T43819","pred":"source","obj":"2_test"},{"subj":"T57689","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ebec","default":true}]}]}}