PMC:7195088 / 9207-9653 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"167","span":{"begin":179,"end":187},"obj":"Species"},{"id":"168","span":{"begin":295,"end":303},"obj":"Species"},{"id":"232","span":{"begin":39,"end":51},"obj":"Disease"},{"id":"233","span":{"begin":73,"end":84},"obj":"Disease"},{"id":"234","span":{"begin":130,"end":139},"obj":"Disease"},{"id":"235","span":{"begin":170,"end":178},"obj":"Disease"},{"id":"236","span":{"begin":271,"end":285},"obj":"Disease"},{"id":"237","span":{"begin":286,"end":294},"obj":"Disease"},{"id":"238","span":{"begin":309,"end":313},"obj":"Disease"},{"id":"239","span":{"begin":339,"end":363},"obj":"Disease"}],"attributes":[{"id":"A167","pred":"tao:has_database_id","subj":"167","obj":"Tax:9606"},{"id":"A168","pred":"tao:has_database_id","subj":"168","obj":"Tax:9606"},{"id":"A232","pred":"tao:has_database_id","subj":"232","obj":"MESH:D007249"},{"id":"A233","pred":"tao:has_database_id","subj":"233","obj":"MESH:D055370"},{"id":"A234","pred":"tao:has_database_id","subj":"234","obj":"MESH:D011014"},{"id":"A235","pred":"tao:has_database_id","subj":"235","obj":"MESH:C000657245"},{"id":"A236","pred":"tao:has_database_id","subj":"236","obj":"MESH:D016638"},{"id":"A237","pred":"tao:has_database_id","subj":"237","obj":"MESH:C000657245"},{"id":"A238","pred":"tao:has_database_id","subj":"238","obj":"MESH:D012128"},{"id":"A239","pred":"tao:has_database_id","subj":"239","obj":"MESH:D012131"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":56,"end":64},"obj":"Body_part"},{"id":"T2","span":{"begin":73,"end":77},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":73,"end":77},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T8","span":{"begin":130,"end":139},"obj":"Phenotype"},{"id":"T9","span":{"begin":344,"end":363},"obj":"Phenotype"}],"attributes":[{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0002878"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T42","span":{"begin":39,"end":51},"obj":"Disease"},{"id":"T43","span":{"begin":78,"end":84},"obj":"Disease"},{"id":"T44","span":{"begin":130,"end":139},"obj":"Disease"},{"id":"T45","span":{"begin":170,"end":178},"obj":"Disease"},{"id":"T46","span":{"begin":286,"end":294},"obj":"Disease"},{"id":"T47","span":{"begin":309,"end":313},"obj":"Disease"},{"id":"T48","span":{"begin":339,"end":343},"obj":"Disease"},{"id":"T49","span":{"begin":344,"end":363},"obj":"Disease"}],"attributes":[{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0021113"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T29","span":{"begin":73,"end":77},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T30","span":{"begin":73,"end":77},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T41","span":{"begin":252,"end":267},"obj":"Chemical"}],"attributes":[{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_50858"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":39,"end":51},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T65","span":{"begin":0,"end":446},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission)."}