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PMC:7195088 / 60263-61274 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1803 118-126 Species denotes patients Tax:9606
1804 295-303 Species denotes patients Tax:9606
1805 309-319 Species denotes SARS-CoV-2 Tax:2697049
1806 504-512 Species denotes patients Tax:9606
1807 631-639 Species denotes patients Tax:9606
1808 1002-1010 Species denotes patients Tax:9606
1809 876-883 Chemical denotes steroid MESH:D013256
1810 948-955 Chemical denotes steroid MESH:D013256
1811 132-152 Disease denotes SARS-CoV-2 infection MESH:C000657245
1812 360-372 Disease denotes inflammation MESH:D007249
1813 394-405 Disease denotes lung injury MESH:D055370
1814 455-464 Disease denotes pneumonia MESH:D011014
1815 495-503 Disease denotes COVID-19 MESH:C000657245
1816 607-621 Disease denotes critically ill MESH:D016638
1817 622-630 Disease denotes COVID-19 MESH:C000657245
1818 645-649 Disease denotes ARDS MESH:D012128
1819 675-699 Disease denotes ARDS respiratory failure MESH:D012131
1820 974-992 Disease denotes non–critically ill MESH:D016638
1821 993-1001 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T95 377-385 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T96 394-398 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T49 394-398 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T101 455-464 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T102 680-699 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T344 132-140 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T345 143-152 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T346 309-317 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T347 360-372 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T348 399-405 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T349 455-464 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T350 495-503 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T351 622-630 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T352 645-649 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T353 675-679 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T354 680-699 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T355 993-1001 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T332 174-186 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T333 394-398 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T334 394-398 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T7997 85-99 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T21891 268-283 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T62412 588-603 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T11802 876-883 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T65 948-955 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T29 360-372 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T441 0-153 Sentence denotes So far, no definitive efficacy or effectiveness data are available on the benefit of corticosteroid administration in patients with SARS-CoV-2 infection.
T442 154-320 Sentence denotes As the World Health Organization underlines, there is an important need for efficacy data from RCT for supporting corticosteroids therapy in patients with SARS-CoV-2.
T443 321-782 Sentence denotes However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for the rapidly progressive pneumonia and clinical deterioration in COVID-19 patients [44,58,67], we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission).
T444 783-1011 Sentence denotes However, in the absence of convincing evidence, the following cannot currently be supported: steroid administration stratified according to inflammatory markers and steroid administration in non–critically ill COVID-19 patients.

2_test

Id Subject Object Predicate Lexical cue
32360444-31986264-22369807 514-516 31986264 denotes 44
32360444-22088618-22369808 517-519 22088618 denotes 58
32360444-32192578-22369809 520-522 32192578 denotes 67