PMC:7195088 / 4898-5716 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"152","span":{"begin":47,"end":55},"obj":"Species"},{"id":"153","span":{"begin":355,"end":362},"obj":"Species"},{"id":"154","span":{"begin":623,"end":631},"obj":"Species"},{"id":"187","span":{"begin":14,"end":20},"obj":"Chemical"},{"id":"188","span":{"begin":341,"end":346},"obj":"Chemical"},{"id":"189","span":{"begin":397,"end":403},"obj":"Chemical"},{"id":"213","span":{"begin":61,"end":88},"obj":"Disease"},{"id":"214","span":{"begin":637,"end":645},"obj":"Disease"}],"attributes":[{"id":"A152","pred":"tao:has_database_id","subj":"152","obj":"Tax:9606"},{"id":"A153","pred":"tao:has_database_id","subj":"153","obj":"Tax:9606"},{"id":"A154","pred":"tao:has_database_id","subj":"154","obj":"Tax:9606"},{"id":"A187","pred":"tao:has_database_id","subj":"187","obj":"MESH:D010100"},{"id":"A188","pred":"tao:has_database_id","subj":"188","obj":"MESH:D014867"},{"id":"A189","pred":"tao:has_database_id","subj":"189","obj":"MESH:D010100"},{"id":"A213","pred":"tao:has_database_id","subj":"213","obj":"MESH:D012131"},{"id":"A214","pred":"tao:has_database_id","subj":"214","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%. Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion). However, no clear indications/criteria can be provided pending further experience. Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":69,"end":88},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002878"}],"text":"Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%. Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion). However, no clear indications/criteria can be provided pending further experience. Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T22","span":{"begin":69,"end":88},"obj":"Disease"},{"id":"T23","span":{"begin":637,"end":645},"obj":"Disease"}],"attributes":[{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0021113"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%. Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion). However, no clear indications/criteria can be provided pending further experience. Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T19","span":{"begin":306,"end":307},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T20","span":{"begin":663,"end":664},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%. Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion). However, no clear indications/criteria can be provided pending further experience. Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T10","span":{"begin":14,"end":20},"obj":"Chemical"},{"id":"T11","span":{"begin":308,"end":312},"obj":"Chemical"},{"id":"T13","span":{"begin":341,"end":346},"obj":"Chemical"},{"id":"T14","span":{"begin":397,"end":403},"obj":"Chemical"}],"attributes":[{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_53359"},{"id":"A12","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_60683"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"}],"text":"Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%. Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion). However, no clear indications/criteria can be provided pending further experience. Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation."}

{"project":"LitCovid-sentences","denotations":[{"id":"T35","span":{"begin":0,"end":194},"obj":"Sentence"},{"id":"T36","span":{"begin":195,"end":499},"obj":"Sentence"},{"id":"T37","span":{"begin":500,"end":582},"obj":"Sentence"},{"id":"T38","span":{"begin":583,"end":818},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%. Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion). However, no clear indications/criteria can be provided pending further experience. Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation."}