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PMC:7195088 / 42615-44426 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1203 982-985 Gene denotes AST Gene:26503
1204 567-575 Species denotes patients Tax:9606
1205 1105-1113 Species denotes patients Tax:9606
1206 1288-1314 Species denotes Mycobacterium tuberculosis Tax:1773
1207 1514-1522 Species denotes patients Tax:9606
1208 84-97 Chemical denotes triglycerides MESH:D014280
1209 1361-1372 Chemical denotes tocilizumab MESH:C502936
1210 30-63 Disease denotes ritonavir • Hypercholesterolaemia MESH:C564286
1211 152-161 Disease denotes Diarrhoea MESH:D003967
1212 245-251 Disease denotes Nausea MESH:D009325
1213 262-295 Disease denotes Upper respiratory tract infection MESH:D012141
1214 304-318 Disease denotes Abdominal pain MESH:D015746
1215 347-354 Disease denotes Fatigue MESH:D005221
1216 409-417 Disease denotes Headache MESH:D006261
1217 427-436 Disease denotes Skin rash MESH:D005076
1218 445-456 Disease denotes Neutropenia MESH:D009503
1219 477-484 Disease denotes Anxiety MESH:D001007
1220 492-500 Disease denotes Insomnia MESH:D007319
1221 540-551 Disease denotes Retinopathy MESH:D012164
1222 634-658 Disease denotes Stevens-Johnson syndrome MESH:D013262
1223 660-674 Disease denotes abdominal pain MESH:D015746
1224 676-685 Disease denotes diarrhoea MESH:D003967
1225 687-693 Disease denotes nausea MESH:D009325
1226 695-703 Disease denotes vomiting MESH:D014839
1227 705-720 Disease denotes agranulocytosis MESH:D000380
1228 722-732 Disease denotes leukopenia MESH:D007970
1229 734-750 Disease denotes thrombocytopenia MESH:D013921
1230 807-815 Disease denotes myopathy MESH:D009135
1231 817-829 Disease denotes bronchospasm MESH:D001986
1232 1065-1076 Disease denotes Neutropenia MESH:D009503
1233 1117-1125 Disease denotes Headache MESH:D006261
1234 1135-1147 Disease denotes Hypertension MESH:D006973
1235 1157-1166 Disease denotes Dizziness MESH:D004244
1236 1174-1188 Disease denotes Hypothyroidism MESH:D007037
1237 1197-1211 Disease denotes Abdominal pain MESH:D015746
1238 1234-1248 Disease denotes gastric ulcers MESH:D013276
1239 1256-1266 Disease denotes Infections MESH:D007239
1240 1274-1286 Disease denotes Pneumocystis MESH:D011020
1241 1589-1597 Disease denotes Headache MESH:D006261
1242 1602-1610 Disease denotes vomiting MESH:D014839
1243 1622-1632 Disease denotes Arthralgia MESH:D018771
1244 1644-1649 Disease denotes Fever MESH:D005334
1245 1661-1682 Disease denotes Haematologic disorder MESH:D006402
1246 1693-1705 Disease denotes eosinophilia MESH:D004802
1247 1707-1717 Disease denotes leukopenia MESH:D007970
1248 1756-1762 Disease denotes Nausea MESH:D009325
1249 1767-1776 Disease denotes diarrhoea MESH:D003967

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T65 78-83 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T66 214-219 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T67 262-285 Body_part denotes Upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T68 372-377 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T69 427-431 Body_part denotes Skin http://purl.org/sig/ont/fma/fma7163
T70 961-966 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T71 1005-1008 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T72 1219-1230 Body_part denotes Oral mucosa http://purl.org/sig/ont/fma/fma59660
T73 1224-1230 Body_part denotes mucosa http://purl.org/sig/ont/fma/fma85355
T74 1475-1483 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T75 1545-1553 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T76 1732-1740 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T36 78-83 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T37 214-219 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T38 262-285 Body_part denotes Upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T39 268-285 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T40 372-377 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T41 427-431 Body_part denotes Skin http://purl.obolibrary.org/obo/UBERON_0000014
T42 961-966 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T43 1224-1230 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T45 68-97 Phenotype denotes increased serum triglycerides http://purl.obolibrary.org/obo/HP_0002155
T46 152-161 Phenotype denotes Diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T47 245-251 Phenotype denotes Nausea http://purl.obolibrary.org/obo/HP_0002018
T48 262-295 Phenotype denotes Upper respiratory tract infection http://purl.obolibrary.org/obo/HP_0002788
T49 304-318 Phenotype denotes Abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T50 329-337 Phenotype denotes Vomiting http://purl.obolibrary.org/obo/HP_0002013
T51 347-354 Phenotype denotes Fatigue http://purl.obolibrary.org/obo/HP_0012378
T52 409-417 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T53 427-436 Phenotype denotes Skin rash http://purl.obolibrary.org/obo/HP_0000988
T54 445-456 Phenotype denotes Neutropenia http://purl.obolibrary.org/obo/HP_0001875
T55 477-484 Phenotype denotes Anxiety http://purl.obolibrary.org/obo/HP_0000739
T56 492-500 Phenotype denotes Insomnia http://purl.obolibrary.org/obo/HP_0100785
T57 540-551 Phenotype denotes Retinopathy http://purl.obolibrary.org/obo/HP_0000488
T58 660-674 Phenotype denotes abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T59 676-685 Phenotype denotes diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T60 687-703 Phenotype denotes nausea, vomiting http://purl.obolibrary.org/obo/HP_0002017
T61 705-720 Phenotype denotes agranulocytosis http://purl.obolibrary.org/obo/HP_0012234
T62 722-732 Phenotype denotes leukopenia http://purl.obolibrary.org/obo/HP_0001882
T63 734-750 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T64 785-798 Phenotype denotes acute hepatic http://purl.obolibrary.org/obo/HP_0200119
T65 807-815 Phenotype denotes myopathy http://purl.obolibrary.org/obo/HP_0003198
T66 817-829 Phenotype denotes bronchospasm http://purl.obolibrary.org/obo/HP_0025428
T67 840-861 Phenotype denotes prolonged QT interval http://purl.obolibrary.org/obo/HP_0001657
T68 995-1020 Phenotype denotes Increased LDL cholesterol http://purl.obolibrary.org/obo/HP_0003141
T69 1065-1076 Phenotype denotes Neutropenia http://purl.obolibrary.org/obo/HP_0001875
T70 1117-1125 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T71 1135-1147 Phenotype denotes Hypertension http://purl.obolibrary.org/obo/HP_0000822
T72 1157-1166 Phenotype denotes Dizziness http://purl.obolibrary.org/obo/HP_0002321
T73 1174-1188 Phenotype denotes Hypothyroidism http://purl.obolibrary.org/obo/HP_0000821
T74 1197-1211 Phenotype denotes Abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T75 1234-1248 Phenotype denotes gastric ulcers http://purl.obolibrary.org/obo/HP_0002592
T76 1589-1597 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T77 1602-1610 Phenotype denotes vomiting http://purl.obolibrary.org/obo/HP_0002013
T78 1622-1632 Phenotype denotes Arthralgia http://purl.obolibrary.org/obo/HP_0002829
T79 1644-1649 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T80 1693-1705 Phenotype denotes eosinophilia http://purl.obolibrary.org/obo/HP_0001880
T81 1707-1717 Phenotype denotes leukopenia http://purl.obolibrary.org/obo/HP_0001882
T82 1756-1762 Phenotype denotes Nausea http://purl.obolibrary.org/obo/HP_0002018
T83 1767-1776 Phenotype denotes diarrhoea http://purl.obolibrary.org/obo/HP_0002014

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T210 152-161 Disease denotes Diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T211 268-295 Disease denotes respiratory tract infection http://purl.obolibrary.org/obo/MONDO_0024355
T212 286-295 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T213 427-436 Disease denotes Skin rash http://purl.obolibrary.org/obo/MONDO_0006547
T214 445-456 Disease denotes Neutropenia http://purl.obolibrary.org/obo/MONDO_0001475
T215 477-484 Disease denotes Anxiety http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918
T217 492-500 Disease denotes Insomnia http://purl.obolibrary.org/obo/MONDO_0013600
T218 540-551 Disease denotes Retinopathy http://purl.obolibrary.org/obo/MONDO_0005283
T219 634-658 Disease denotes Stevens-Johnson syndrome http://purl.obolibrary.org/obo/MONDO_0018229
T220 642-658 Disease denotes Johnson syndrome http://purl.obolibrary.org/obo/MONDO_0019419
T221 676-685 Disease denotes diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T222 705-720 Disease denotes agranulocytosis http://purl.obolibrary.org/obo/MONDO_0001609
T223 722-732 Disease denotes leukopenia http://purl.obolibrary.org/obo/MONDO_0003785
T224 734-750 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T225 807-815 Disease denotes myopathy http://purl.obolibrary.org/obo/MONDO_0005336
T226 817-829 Disease denotes bronchospasm http://purl.obolibrary.org/obo/MONDO_0001358
T227 1065-1076 Disease denotes Neutropenia http://purl.obolibrary.org/obo/MONDO_0001475
T228 1135-1147 Disease denotes Hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T229 1174-1188 Disease denotes Hypothyroidism http://purl.obolibrary.org/obo/MONDO_0005420
T230 1234-1248 Disease denotes gastric ulcers http://purl.obolibrary.org/obo/MONDO_0001126
T231 1242-1248 Disease denotes ulcers http://purl.obolibrary.org/obo/MONDO_0043839
T232 1274-1286 Disease denotes Pneumocystis http://purl.obolibrary.org/obo/MONDO_0019121
T233 1302-1314 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T234 1319-1328 Disease denotes varicella http://purl.obolibrary.org/obo/MONDO_0005700
T235 1329-1335 Disease denotes zoster http://purl.obolibrary.org/obo/MONDO_0005609
T236 1693-1705 Disease denotes eosinophilia http://purl.obolibrary.org/obo/MONDO_0015691
T237 1707-1717 Disease denotes leukopenia http://purl.obolibrary.org/obo/MONDO_0003785
T238 1767-1776 Disease denotes diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T239 231-234 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3/4
T240 238-240 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T241 322-324 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T242 339-342 http://purl.obolibrary.org/obo/CLO_0050509 denotes 2–7
T243 427-431 http://purl.obolibrary.org/obo/UBERON_0000014 denotes Skin
T244 427-431 http://purl.obolibrary.org/obo/UBERON_0001003 denotes Skin
T245 427-431 http://purl.obolibrary.org/obo/UBERON_0002097 denotes Skin
T246 427-431 http://purl.obolibrary.org/obo/UBERON_0002199 denotes Skin
T247 427-431 http://www.ebi.ac.uk/efo/EFO_0000962 denotes Skin
T248 464-467 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3/4
T249 576-577 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T250 778-783 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T251 973-975 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T252 988-990 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T253 1087-1090 http://purl.obolibrary.org/obo/CLO_0050509 denotes 2–7
T254 1224-1230 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
T255 1395-1398 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T256 1468-1470 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T528 20-29 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T529 30-39 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T530 84-97 Chemical denotes triglycerides http://purl.obolibrary.org/obo/CHEBI_17855
T531 120-128 Chemical denotes glutamyl http://purl.obolibrary.org/obo/CHEBI_32483
T532 507-518 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T533 519-537 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T534 924-936 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T535 982-985 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T536 1005-1020 Chemical denotes LDL cholesterol http://purl.obolibrary.org/obo/CHEBI_47774
T537 1005-1008 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T538 1009-1020 Chemical denotes cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T539 1361-1372 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T313 0-19 Sentence denotes Drug Adverse events
T314 20-105 Sentence denotes Lopinavir/ritonavir • Hypercholesterolaemia and increased serum triglycerides (3–39%)
T315 106-149 Sentence denotes • Increased γ-glutamyl transferase (10–29%)
T316 150-201 Sentence denotes • Diarrhoea (7–28%; greater with once-daily dosing)
T317 202-235 Sentence denotes • Increased serum ALT (grade 3/4:
T318 236-242 Sentence denotes 1–11%)
T319 243-259 Sentence denotes • Nausea (5–16%)
T320 260-301 Sentence denotes • Upper respiratory tract infection (14%)
T321 302-326 Sentence denotes • Abdominal pain (1–11%)
T322 327-344 Sentence denotes • Vomiting (2–7%)
T323 345-359 Sentence denotes • Fatigue (8%)
T324 360-406 Sentence denotes • Increased serum amylase and/or lipase (3–8%)
T325 407-424 Sentence denotes • Headache (2–6%)
T326 425-442 Sentence denotes • Skin rash (≤5%)
T327 443-468 Sentence denotes • Neutropenia (grade 3/4:
T328 469-474 Sentence denotes 1–5%)
T329 475-489 Sentence denotes • Anxiety (4%)
T330 490-506 Sentence denotes • Insomnia (≤4%)
T331 507-577 Sentence denotes Chloroquine/hydroxychloroquine • Retinopathy (4% of treated patients)a
T332 578-829 Sentence denotes • Other adverse effects with unknown frequency included Stevens-Johnson syndrome, abdominal pain, diarrhoea, nausea, vomiting, agranulocytosis, leukopenia, thrombocytopenia, abnormal hepatic function tests, acute hepatic ailure, myopathy, bronchospasm
T333 830-936 Sentence denotes • Risk of prolonged QT interval, further increased when administered with fluoroquinolones or azithromycin
T334 937-992 Sentence denotes Tocilizumab • Increased serum ALT (≤36%) and AST (≤22%)
T335 993-1028 Sentence denotes • Increased LDL cholesterol (9–10%)
T336 1029-1062 Sentence denotes • Injection site reaction (4–10%)
T337 1063-1086 Sentence denotes • Neutropenia (grade 3:
T338 1087-1114 Sentence denotes 2–7% of all adult patients)
T339 1115-1132 Sentence denotes • Headache (1–7%)
T340 1133-1154 Sentence denotes • Hypertension (1–6%)
T341 1155-1171 Sentence denotes • Dizziness (3%)
T342 1172-1194 Sentence denotes • Hypothyroidism (<2%)
T343 1195-1216 Sentence denotes • Abdominal pain (2%)
T344 1217-1253 Sentence denotes • Oral mucosa or gastric ulcers (2%)
T345 1254-1427 Sentence denotes • Infections due to Pneumocystis, Mycobacterium tuberculosis and varicella zoster have been reported after tocilizumab, but their prevalence has not been clearly established
T346 1428-1472 Sentence denotes Anakinra • Injection site reactionb (24–71%)
T347 1473-1586 Sentence denotes • Antibody development (up to 50% of the patients but no correlation of antibody development and adverse effects)
T348 1587-1619 Sentence denotes • Headache and vomiting (12–14%)
T349 1620-1641 Sentence denotes • Arthralgia (10–12%)
T350 1642-1658 Sentence denotes • Fever (10–12%)
T351 1659-1753 Sentence denotes • Haematologic disorder including eosinophilia, leukopenia and change in platelet count (2–9%)
T352 1754-1783 Sentence denotes • Nausea and diarrhoea (7–8%)
T353 1784-1811 Sentence denotes • Serious infectionc (2–3%)