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PMC:7195088 / 3587-35170 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
152 1358-1366 Species denotes patients Tax:9606
153 1666-1673 Species denotes patient Tax:9606
154 1934-1942 Species denotes patients Tax:9606
155 2304-2312 Species denotes patients Tax:9606
156 2554-2562 Species denotes patients Tax:9606
157 3137-3145 Species denotes patients Tax:9606
158 3339-3349 Species denotes SARS-CoV-2 Tax:2697049
159 4065-4073 Species denotes patients Tax:9606
160 4288-4296 Species denotes patients Tax:9606
161 4457-4465 Species denotes patients Tax:9606
162 4781-4789 Species denotes patients Tax:9606
163 4939-4947 Species denotes patients Tax:9606
164 5440-5448 Species denotes patients Tax:9606
165 5594-5602 Species denotes patients Tax:9606
166 5608-5618 Species denotes SARS-Cov-2 Tax:2697049
167 5799-5807 Species denotes patients Tax:9606
168 5915-5923 Species denotes patients Tax:9606
169 6290-6298 Species denotes patients Tax:9606
170 6469-6477 Species denotes patients Tax:9606
171 6656-6664 Species denotes patients Tax:9606
172 7005-7013 Species denotes patients Tax:9606
173 7684-7692 Species denotes patients Tax:9606
174 8066-8073 Species denotes patient Tax:9606
175 8320-8328 Species denotes patients Tax:9606
176 8454-8462 Species denotes patients Tax:9606
177 8573-8581 Species denotes patients Tax:9606
178 8583-8591 Species denotes patients Tax:9606
179 8740-8748 Species denotes patients Tax:9606
180 8922-8930 Species denotes patients Tax:9606
181 9151-9159 Species denotes patients Tax:9606
182 9477-9485 Species denotes patients Tax:9606
183 10044-10051 Species denotes patient Tax:9606
184 2964-2973 Species denotes influenza Tax:11520
185 8490-8499 Species denotes influenza Tax:11520
186 1230-1236 Chemical denotes oxygen MESH:D010100
187 1325-1331 Chemical denotes oxygen MESH:D010100
188 1652-1657 Chemical denotes water MESH:D014867
189 1708-1714 Chemical denotes oxygen MESH:D010100
190 2284-2291 Chemical denotes LPV/RTV MESH:C558899
191 2392-2401 Chemical denotes darunavir MESH:D000069454
192 2502-2512 Chemical denotes remdesivir MESH:C000606551
193 2722-2733 Chemical denotes favipiravir MESH:C462182
194 2738-2748 Chemical denotes umifenovir MESH:C086979
195 2867-2878 Chemical denotes Oseltamivir MESH:D053139
196 2882-2891 Chemical denotes zanamivir MESH:D053243
197 2994-3024 Chemical denotes chloroquine/hydroxychloroquine
198 3077-3095 Chemical denotes hydroxychloroquine MESH:D006886
199 3694-3712 Chemical denotes hydroxychloroquine MESH:D006886
200 3992-4010 Chemical denotes hydroxychloroquine MESH:D006886
201 5296-5304 Chemical denotes steroids MESH:D013256
202 6159-6166 Chemical denotes steroid MESH:D013256
203 6236-6243 Chemical denotes steroid MESH:D013256
204 6454-6465 Chemical denotes tocilizumab MESH:C502936
205 6936-6947 Chemical denotes tocilizumab MESH:C502936
206 7992-7998 Chemical denotes oxygen MESH:D010100
207 8428-8439 Chemical denotes oseltamivir MESH:D053139
208 8858-8876 Chemical denotes hydroxychloroquine MESH:D006886
209 9093-9111 Chemical denotes hydroxychloroquine MESH:D006886
210 9213-9243 Chemical denotes Chloroquine/hydroxychloroquine
211 9666-9676 Chemical denotes remdesivir MESH:C000606551
212 10128-10135 Chemical denotes steroid MESH:D013256
213 1372-1399 Disease denotes hypoxic respiratory failure MESH:D012131
214 1948-1956 Disease denotes COVID-19 MESH:C000657245
215 2295-2303 Disease denotes COVID-19 MESH:C000657245
216 2545-2553 Disease denotes COVID-19 MESH:C000657245
217 3151-3159 Disease denotes COVID-19 MESH:C000657245
218 3275-3290 Disease denotes QT prolongation MESH:D008133
219 3664-3673 Disease denotes mortality MESH:D003643
220 4273-4287 Disease denotes critically ill MESH:D016638
221 4302-4311 Disease denotes pneumonia MESH:D011014
222 4319-4327 Disease denotes COVID-19 MESH:C000657245
223 4336-4355 Disease denotes bacterial infection MESH:D001424
224 4428-4439 Disease denotes coinfection MESH:D060085
225 4471-4486 Disease denotes viral pneumonia
226 4603-4612 Disease denotes mortality MESH:D003643
227 4772-4780 Disease denotes COVID-19 MESH:C000657245
228 4930-4938 Disease denotes COVID-19 MESH:C000657245
229 5010-5019 Disease denotes pneumonia MESH:D011014
230 5039-5048 Disease denotes pneumonia MESH:D011014
231 5454-5474 Disease denotes SARS-CoV-2 infection MESH:C000657245
232 5659-5671 Disease denotes inflammation MESH:D007249
233 5693-5704 Disease denotes lung injury MESH:D055370
234 5750-5759 Disease denotes pneumonia MESH:D011014
235 5790-5798 Disease denotes COVID-19 MESH:C000657245
236 5891-5905 Disease denotes critically ill MESH:D016638
237 5906-5914 Disease denotes COVID-19 MESH:C000657245
238 5929-5933 Disease denotes ARDS MESH:D012128
239 5959-5983 Disease denotes ARDS respiratory failure MESH:D012131
240 6262-6280 Disease denotes non–critically ill MESH:D016638
241 6281-6289 Disease denotes COVID-19 MESH:C000657245
242 6483-6491 Disease denotes COVID-19 MESH:C000657245
243 6647-6655 Disease denotes COVID-19 MESH:C000657245
244 6863-6873 Disease denotes infections MESH:D007239
245 6977-6985 Disease denotes COVID-19 MESH:C000657245
246 7829-7837 Disease denotes COVID-19 MESH:C000657245
247 8135-8143 Disease denotes asthenia MESH:D001247
248 8150-8155 Disease denotes fever MESH:D005334
249 8168-8173 Disease denotes cough MESH:D003371
250 8334-8354 Disease denotes SARS-CoV-2 infection MESH:C000657245
251 8597-8601 Disease denotes ARDS MESH:D012128
252 8627-8651 Disease denotes ARDS respiratory failure MESH:D012131
253 8731-8739 Disease denotes COVID-19 MESH:C000657245
254 8913-8921 Disease denotes COVID-19 MESH:C000657245
255 9081-9089 Disease denotes toxicity MESH:D064420
256 9468-9476 Disease denotes COVID-19 MESH:C000657245
257 9597-9638 Disease denotes QT prolongation or hepatic/renal toxicity MESH:D056486
265 10591-10601 Species denotes SARS-CoV-2 Tax:2697049
266 10603-10650 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
267 10487-10494 Chemical denotes LPV/RTV MESH:C558899
268 10496-10515 Chemical denotes lopinavir/ritonavir MESH:C558899
269 10308-10312 Disease denotes ARDS MESH:D012128
270 10314-10349 Disease denotes acute respiratory distress syndrome MESH:D012128
271 10361-10385 Disease denotes coronavirus disease 2019 MESH:C000657245
643 11094-11100 Gene denotes CYP3A4 Gene:1576
644 18966-18972 Gene denotes CYP3A4 Gene:1576
653 11199-11207 Species denotes patients Tax:9606
654 11239-11247 Species denotes patients Tax:9606
655 12117-12125 Species denotes patients Tax:9606
656 12307-12315 Species denotes patients Tax:9606
657 12651-12659 Species denotes patients Tax:9606
658 12896-12904 Species denotes patients Tax:9606
659 13145-13153 Species denotes patients Tax:9606
660 13850-13858 Species denotes patients Tax:9606
661 14276-14284 Species denotes patients Tax:9606
662 14558-14566 Species denotes patients Tax:9606
663 14850-14858 Species denotes patients Tax:9606
664 15166-15174 Species denotes patients Tax:9606
665 15434-15442 Species denotes patients Tax:9606
666 15743-15751 Species denotes patients Tax:9606
667 16169-16177 Species denotes patients Tax:9606
668 16534-16542 Species denotes patients Tax:9606
669 16775-16783 Species denotes patients Tax:9606
670 17048-17056 Species denotes patients Tax:9606
671 17159-17169 Species denotes SARS-CoV-2 Tax:2697049
672 17375-17383 Species denotes patients Tax:9606
673 17582-17590 Species denotes patients Tax:9606
674 17798-17806 Species denotes patients Tax:9606
675 18036-18044 Species denotes patients Tax:9606
676 18200-18208 Species denotes patients Tax:9606
677 18432-18440 Species denotes patients Tax:9606
678 18732-18740 Species denotes patients Tax:9606
679 19097-19105 Species denotes patients Tax:9606
680 19430-19438 Species denotes patients Tax:9606
681 19481-19489 Species denotes patients Tax:9606
682 19563-19571 Species denotes patients Tax:9606
728 11012-11031 Chemical denotes Lopinavir/ritonavir MESH:C558899
729 11032-11041 Chemical denotes Lopinavir MESH:D061466
730 11079-11088 Chemical denotes Ritonavir MESH:D019438
731 11123-11132 Chemical denotes lopinavir MESH:D061466
732 11175-11194 Chemical denotes lopinavir/ritonavir MESH:C558899
733 11272-11291 Chemical denotes Lopinavir/ritonavir MESH:C558899
734 11843-11862 Chemical denotes lopinavir/ritonavir MESH:C558899
735 12071-12090 Chemical denotes lopinavir/ritonavir MESH:C558899
736 12095-12113 Chemical denotes hydroxychloroquine MESH:D006886
737 12264-12269 Chemical denotes ASC09
738 12270-12279 Chemical denotes ritonavir MESH:D019438
739 12284-12303 Chemical denotes lopinavir/ritonavir MESH:C558899
740 12480-12486 Chemical denotes oxygen MESH:D010100
741 12509-12513 Chemical denotes FiO2
742 12588-12607 Chemical denotes lopinavir/ritonavir MESH:C558899
743 12612-12631 Chemical denotes lopinavir/ritonavir MESH:C558899
744 12637-12647 Chemical denotes umifenovir MESH:C086979
745 12810-12829 Chemical denotes lopinavir/ritonavir MESH:C558899
746 12834-12853 Chemical denotes lopinavir/ritonavir MESH:C558899
747 12859-12868 Chemical denotes ribavirin MESH:D012254
748 13091-13110 Chemical denotes lopinavir/ritonavir MESH:C558899
749 13115-13126 Chemical denotes oseltamivir MESH:D053139
750 13131-13141 Chemical denotes umifenovir MESH:C086979
751 13545-13564 Chemical denotes lopinavir/ritonavir MESH:C558899
752 13783-13793 Chemical denotes carrimycin
753 13798-13817 Chemical denotes lopinavir/ritonavir MESH:C558899
754 13821-13831 Chemical denotes umifenovir MESH:C086979
755 13835-13846 Chemical denotes chloroquine MESH:D002738
756 14133-14152 Chemical denotes lopinavir/ritonavir MESH:C558899
757 14157-14176 Chemical denotes lopinavir/ritonavir MESH:C558899
758 14428-14447 Chemical denotes lopinavir/ritonavir MESH:C558899
759 14481-14500 Chemical denotes lopinavir/ritonavir MESH:C558899
760 14535-14544 Chemical denotes xiyanping
761 14710-14729 Chemical denotes lopinavir/ritonavir MESH:C558899
762 14763-14782 Chemical denotes lopinavir/ritonavir MESH:C558899
763 15010-15029 Chemical denotes lopinavir/ritonavir MESH:C558899
764 15035-15053 Chemical denotes hydroxychloroquine MESH:D006886
765 15058-15077 Chemical denotes lopinavir/ritonavir MESH:C558899
766 15083-15101 Chemical denotes hydroxychloroquine MESH:D006886
767 15107-15117 Chemical denotes levamisole MESH:D007978
768 15128-15138 Chemical denotes budesonide MESH:D019819
769 15144-15154 Chemical denotes formoterol MESH:D000068759
770 15362-15381 Chemical denotes lopinavir/ritonavir MESH:C558899
771 15386-15404 Chemical denotes hydroxychloroquine MESH:D006886
772 15409-15417 Chemical denotes losartan MESH:D019808
773 15613-15632 Chemical denotes lopinavir/ritonavir MESH:C558899
774 15637-15655 Chemical denotes hydroxychloroquine MESH:D006886
775 15660-15679 Chemical denotes lopinavir/ritonavir MESH:C558899
776 15708-15718 Chemical denotes remdesivir MESH:C000606551
777 15909-15928 Chemical denotes lopinavir/ritonavir MESH:C558899
778 15932-15942 Chemical denotes umifenovir MESH:C086979
779 15946-15957 Chemical denotes chloroquine MESH:D002738
780 15961-15979 Chemical denotes hydroxychloroquine MESH:D006886
781 15983-15994 Chemical denotes oseltamivir MESH:D053139
782 16012-16024 Chemical denotes azithromycin MESH:D017963
783 16049-16068 Chemical denotes lopinavir/ritonavir MESH:C558899
784 16072-16082 Chemical denotes umifenovir MESH:C086979
785 16086-16097 Chemical denotes chloroquine MESH:D002738
786 16101-16119 Chemical denotes hydroxychloroquine MESH:D006886
787 16123-16134 Chemical denotes oseltamivir MESH:D053139
788 16152-16164 Chemical denotes azithromycin MESH:D017963
789 16455-16465 Chemical denotes colchicine MESH:D003078
790 16483-16502 Chemical denotes lopinavir/ritonavir MESH:C558899
791 16752-16771 Chemical denotes lopinavir/ritonavir MESH:C558899
792 16810-16829 Chemical denotes lopinavir/ritonavir MESH:C558899
793 16909-16928 Chemical denotes lopinavir/ritonavir MESH:C558899
794 17209-17219 Chemical denotes Remdesivir MESH:C000606551
795 17220-17229 Chemical denotes Adenosine MESH:D000241
796 17349-17359 Chemical denotes remdesivir MESH:C000606551
797 17556-17566 Chemical denotes remdesivir MESH:C000606551
798 17757-17767 Chemical denotes remdesivir MESH:C000606551
799 17926-17932 Chemical denotes oxygen MESH:D010100
800 17995-18005 Chemical denotes remdesivir MESH:C000606551
801 18174-18184 Chemical denotes remdesivir MESH:C000606551
802 18356-18366 Chemical denotes remdesivir MESH:C000606551
803 18371-18389 Chemical denotes hydroxychloroquine MESH:D006886
804 18394-18404 Chemical denotes remdesivir MESH:C000606551
805 18410-18428 Chemical denotes hydroxychloroquine MESH:D006886
806 18602-18621 Chemical denotes lopinavir/ritonavir MESH:C558899
807 18626-18644 Chemical denotes hydroxychloroquine MESH:D006886
808 18649-18668 Chemical denotes lopinavir/ritonavir MESH:C558899
809 18697-18707 Chemical denotes remdesivir MESH:C000606551
810 18882-18891 Chemical denotes Darunavir MESH:D000069454
811 18892-18912 Chemical denotes cobicistat Darunavir
812 18995-19004 Chemical denotes darunavir MESH:D000069454
813 19288-19299 Chemical denotes Favipiravir MESH:C462182
814 19452-19463 Chemical denotes favipiravir MESH:C462182
815 19500-19510 Chemical denotes umifenovir MESH:C086979
816 19582-19593 Chemical denotes favipiravir MESH:C462182
905 10935-10943 Disease denotes COVID-19 MESH:C000657245
906 11253-11261 Disease denotes COVID-19 MESH:C000657245
907 11687-11696 Disease denotes mortality MESH:D003643
908 12136-12144 Disease denotes COVID-19 MESH:C000657245
909 12331-12339 Disease denotes COVID-19 MESH:C000657245
910 12665-12673 Disease denotes COVID-19 MESH:C000657245
911 12910-12918 Disease denotes COVID-19 MESH:C000657245
912 13169-13187 Disease denotes COVID-19 pneumonia MESH:C000657245
913 13295-13300 Disease denotes fever MESH:D005334
914 13302-13307 Disease denotes cough MESH:D003371
915 13375-13380 Disease denotes fever MESH:D005334
916 13382-13387 Disease denotes cough MESH:D003371
917 13610-13618 Disease denotes COVID-19 MESH:C000657245
918 13734-13742 Disease denotes COVID-19 MESH:C000657245
919 13864-13882 Disease denotes COVID-19 pneumonia MESH:C000657245
920 13957-13962 Disease denotes fever MESH:D005334
921 14003-14025 Disease denotes pulmonary inflammation MESH:D011014
922 14290-14298 Disease denotes COVID-19 MESH:C000657245
923 14572-14580 Disease denotes COVID-19 MESH:C000657245
924 14864-14872 Disease denotes COVID-19 MESH:C000657245
925 15190-15208 Disease denotes COVID-19 pneumonia MESH:C000657245
926 15448-15456 Disease denotes COVID-19 MESH:C000657245
927 15544-15552 Disease denotes COVID-19 MESH:C000657245
928 15757-15765 Disease denotes COVID-19 MESH:C000657245
929 16183-16191 Disease denotes COVID-19 MESH:C000657245
930 16310-16315 Disease denotes fever MESH:D005334
931 16385-16402 Disease denotes lung inflammation MESH:D011014
932 16567-16575 Disease denotes COVID-19 MESH:C000657245
933 16655-16664 Disease denotes mortality MESH:D003643
934 16794-16802 Disease denotes COVID-19 MESH:C000657245
935 17001-17032 Disease denotes ritonavir plus favipiravir plus MESH:D007625
936 17081-17089 Disease denotes COVID-19 MESH:C000657245
937 17396-17404 Disease denotes COVID-19 MESH:C000657245
938 17613-17621 Disease denotes COVID-19 MESH:C000657245
939 17819-17827 Disease denotes COVID-19 MESH:C000657245
940 17902-17907 Disease denotes fever MESH:D005334
941 18059-18067 Disease denotes COVID-19 MESH:C000657245
942 18214-18222 Disease denotes COVID-19 MESH:C000657245
943 18446-18454 Disease denotes COVID-19 MESH:C000657245
944 18555-18564 Disease denotes mortality MESH:D003643
945 18746-18754 Disease denotes COVID-19 MESH:C000657245
946 19111-19129 Disease denotes COVID-19 pneumonia MESH:C000657245
947 19421-19429 Disease denotes COVID-19 MESH:C000657245
948 19472-19480 Disease denotes COVID-19 MESH:C000657245
1015 10842-10850 Disease denotes COVID-19 MESH:C000657245
1022 30957-30965 Species denotes patients Tax:9606
1023 31021-31032 Chemical denotes ruxolitinib MESH:C540383
1024 31034-31045 Chemical denotes baricitinib MESH:C000596027
1025 31050-31061 Chemical denotes tofacitinib MESH:C479163
1026 30817-30825 Disease denotes COVID-19 MESH:C000657245
1027 30971-30979 Disease denotes COVID-19 MESH:C000657245
1035 31255-31259 Gene denotes IL-1 Gene:3552
1036 31261-31274 Gene denotes interleukin 1 Gene:3552
1037 31491-31501 Species denotes SARS-CoV-2 Tax:2697049
1038 31503-31550 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
1039 31064-31068 Disease denotes ARDS MESH:D012128
1040 31071-31106 Disease denotes acute respiratory distress syndrome MESH:D012128
1041 31143-31167 Disease denotes coronavirus disease 2019 MESH:C000657245
1047 895-903 Species denotes patients Tax:9606
1048 268-287 Disease denotes infectious diseases MESH:D003141
1049 886-894 Disease denotes COVID-19 MESH:C000657245
1050 1035-1043 Disease denotes COVID-19 MESH:C000657245
1051 1052-1088 Disease denotes cardiovascular/coagulative disorders MESH:D002318

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 5676-5684 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T2 5693-5697 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T3 7640-7655 Body_part denotes immunoglobulins http://purl.org/sig/ont/fma/fma62871
T4 7659-7665 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T5 8213-8217 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T6 10092-10096 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T7 11048-11051 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T8 13350-13354 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T9 13430-13434 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 13492-13496 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T11 14090-14096 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T12 16385-16389 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T13 17252-17255 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T14 17266-17269 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T15 17296-17299 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T16 18919-18922 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T17 19219-19225 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T18 19233-19239 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T19 19243-19266 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662
T20 19315-19318 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T21 19329-19332 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T22 20940-20946 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T23 22398-22407 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T24 22440-22444 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T25 22492-22496 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T26 25482-25488 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T27 25748-25751 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T28 25810-25813 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T29 26217-26225 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T30 26378-26386 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T31 26574-26578 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T32 27353-27355 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T33 27369-27377 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T34 27569-27577 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T35 27632-27634 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T36 27648-27650 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T37 27748-27756 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T38 29111-29124 Body_part denotes interleukin 6 http://purl.org/sig/ont/fma/fma264829
T39 29111-29122 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T40 29147-29155 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T41 29418-29422 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T42 29418-29420 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T43 30007-30013 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T44 30057-30061 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T45 30057-30059 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T46 30072-30076 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T47 30072-30074 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T48 30158-30166 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T49 30271-30279 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T50 30480-30484 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T51 30480-30482 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T52 31239-31253 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T53 31255-31259 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T54 31255-31257 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T55 31261-31274 Body_part denotes interleukin 1 http://purl.org/sig/ont/fma/fma86583
T56 31261-31272 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 5693-5697 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 8084-8107 Body_part denotes respiratory or systemic http://purl.obolibrary.org/obo/UBERON_0001004
T3 8213-8217 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 10092-10096 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 13350-13354 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 13430-13434 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 13492-13496 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 14090-14096 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T9 15570-15575 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T10 15876-15881 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T11 16385-16389 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T12 17508-17513 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T13 18323-18328 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T14 18865-18870 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T15 19219-19225 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T16 19233-19239 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T17 19243-19266 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T18 19249-19266 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T19 20940-20946 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T20 24939-24944 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T21 25426-25431 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T22 26121-26126 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T23 26574-26578 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T24 27983-27988 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T25 28044-28049 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T26 28439-28444 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T27 30007-30013 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 1380-1399 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T4 4302-4311 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 4477-4486 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T6 5010-5019 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T7 5039-5048 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T8 5750-5759 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T9 5964-5983 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T10 8135-8143 Phenotype denotes asthenia http://purl.obolibrary.org/obo/HP_0025406
T11 8150-8155 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T12 8168-8173 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T13 8632-8651 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T14 10320-10340 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T15 12340-12350 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T16 13178-13187 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T17 13295-13300 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T18 13302-13307 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T19 13375-13380 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T20 13382-13387 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T21 13873-13882 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T22 13957-13962 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T23 15199-15208 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T24 16310-16315 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T25 17902-17907 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T26 19120-19129 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T27 22176-22185 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T28 26217-26231 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T29 26274-26283 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T30 28912-28918 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T31 29790-29799 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T32 29874-29879 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T33 30158-30183 Phenotype denotes cytokine-release syndrome http://purl.obolibrary.org/obo/HP_0033041
T34 31077-31097 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T19 268-278 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T20 886-894 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 1035-1043 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 1380-1399 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T23 1948-1956 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 2295-2303 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 2545-2553 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 2964-2973 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T27 3151-3159 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 3339-3347 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 4302-4311 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T30 4319-4327 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 4336-4355 Disease denotes bacterial infection http://purl.obolibrary.org/obo/MONDO_0005113
T32 4346-4355 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T33 4471-4486 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T34 4477-4486 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T35 4772-4780 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 4930-4938 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 5010-5019 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T38 5039-5048 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T39 5454-5462 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 5465-5474 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T41 5608-5612 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T42 5659-5671 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T43 5698-5704 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T44 5750-5759 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T45 5790-5798 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 5906-5914 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 5929-5933 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T48 5959-5963 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T49 5964-5983 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T50 6281-6289 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T51 6483-6491 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 6647-6655 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T53 6863-6873 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T54 6977-6985 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T55 7829-7837 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T56 8334-8342 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T57 8345-8354 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 8490-8499 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T59 8597-8601 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T60 8627-8631 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T61 8632-8651 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T62 8731-8739 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 8913-8921 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T64 9468-9476 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T65 10308-10312 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T66 10314-10349 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T67 10320-10349 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T68 10351-10359 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 10361-10385 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T70 10591-10599 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 10603-10650 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T72 10603-10636 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T73 10842-10850 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 10935-10943 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T75 11253-11261 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 12136-12144 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T77 12331-12339 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 12340-12350 Disease denotes pneumoniae http://purl.obolibrary.org/obo/MONDO_0005249
T79 12665-12673 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T80 12910-12918 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T81 13169-13177 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T82 13178-13187 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T83 13610-13618 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 13734-13742 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 13864-13872 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 13873-13882 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T87 14013-14025 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T88 14290-14298 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T89 14572-14580 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T90 14864-14872 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T91 15190-15198 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 15199-15208 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T93 15448-15456 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T94 15544-15552 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 15757-15765 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T96 16183-16191 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T97 16390-16402 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T98 16567-16575 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T99 16794-16802 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T100 17081-17089 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T101 17159-17167 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 17396-17404 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T103 17613-17621 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T104 17819-17827 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 18059-18067 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T106 18214-18222 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 18446-18454 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T108 18746-18754 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T109 19111-19119 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T110 19120-19129 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T111 19305-19314 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T112 19421-19429 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T113 19472-19480 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T114 19761-19769 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T115 19975-19983 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T116 20262-20270 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T117 20340-20348 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T118 20489-20497 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T119 20749-20757 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 21041-21049 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 21322-21330 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T122 21609-21617 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 21687-21695 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 21753-21762 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T125 21856-21864 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T126 21907-21915 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 22167-22175 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 22176-22185 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T129 22958-22966 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T130 23077-23085 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T131 23187-23195 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T132 23344-23352 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 23622-23630 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 23700-23708 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T135 23820-23828 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T136 23976-23984 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T137 24025-24033 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T138 24215-24223 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T139 24339-24347 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 24473-24481 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T141 24597-24605 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T142 24608-24617 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T143 24704-24712 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T144 24856-24864 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T145 25062-25070 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T146 25304-25312 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 25400-25408 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 25602-25610 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T149 25752-25760 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T150 26002-26010 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T151 26192-26200 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T152 26226-26240 Disease denotes storm syndrome http://purl.obolibrary.org/obo/MONDO_0008496
T153 26274-26283 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T154 26285-26289 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T155 26491-26499 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T156 26579-26585 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T157 26683-26691 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T158 26983-26991 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T159 27186-27194 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T160 27419-27427 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T161 27798-27806 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T162 27889-27897 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T163 28146-28154 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T164 28322-28330 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T165 28583-28591 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T166 28901-28918 Disease denotes metastatic cancer http://purl.obolibrary.org/obo/MONDO_0024880
T167 28912-28918 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T168 28923-28931 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T169 29210-29218 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T170 29556-29564 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T171 29781-29789 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T172 29790-29799 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T173 29930-29942 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T174 30319-30327 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T175 30618-30626 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T176 30817-30825 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 30971-30979 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T178 31064-31068 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T179 31071-31106 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T180 31077-31106 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T181 31133-31141 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T182 31143-31167 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T183 31491-31499 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T184 31503-31550 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T185 31503-31536 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T12 11-12 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T13 166-167 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 487-488 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 623-624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 648-649 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T17 823-828 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T18 917-924 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T19 1617-1618 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 1974-1975 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 2263-2268 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T22 3313-3321 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T23 3440-3445 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T24 3461-3462 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 3829-3834 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T26 4441-4442 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 4492-4493 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T28 4518-4519 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 5693-5697 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T30 5693-5697 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T31 6233-6234 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T32 6553-6558 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T33 6906-6907 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 6923-6928 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T35 7074-7075 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T36 7080-7084 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T37 7080-7084 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T38 7214-7215 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T39 7659-7665 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T40 8084-8107 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory or systemic
T41 8213-8217 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T42 8213-8217 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T43 9963-9964 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 10092-10096 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T45 10092-10096 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T46 10200-10201 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 10413-10419 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T48 10670-10682 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T49 10785-10790 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T50 11092-11093 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T51 11155-11160 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T52 11748-11752 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T53 11870-11871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 12043-12045 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T55 12051-12053 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T56 12151-12156 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T57 12206-12211 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T58 12224-12228 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3, 5
T59 12244-12246 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T60 12357-12362 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T61 12464-12470 http://purl.obolibrary.org/obo/CLO_0001230 denotes 2 ≤ 93
T62 12464-12470 http://purl.obolibrary.org/obo/CLO_0037237 denotes 2 ≤ 93
T63 12464-12470 http://purl.obolibrary.org/obo/CLO_0050903 denotes 2 ≤ 93
T64 12464-12470 http://purl.obolibrary.org/obo/CLO_0054249 denotes 2 ≤ 93
T65 12464-12470 http://purl.obolibrary.org/obo/CLO_0054250 denotes 2 ≤ 93
T66 12464-12470 http://purl.obolibrary.org/obo/CLO_0054251 denotes 2 ≤ 93
T67 12464-12470 http://purl.obolibrary.org/obo/CLO_0054252 denotes 2 ≤ 93
T68 12680-12685 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T69 12743-12748 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T70 12925-12930 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T71 13194-13199 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T72 13251-13252 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 13350-13354 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T74 13350-13354 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T75 13430-13434 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T76 13430-13434 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T77 13443-13449 http://purl.obolibrary.org/obo/CLO_0001230 denotes 2 > 93
T78 13443-13449 http://purl.obolibrary.org/obo/CLO_0037237 denotes 2 > 93
T79 13443-13449 http://purl.obolibrary.org/obo/CLO_0050903 denotes 2 > 93
T80 13443-13449 http://purl.obolibrary.org/obo/CLO_0054249 denotes 2 > 93
T81 13443-13449 http://purl.obolibrary.org/obo/CLO_0054250 denotes 2 > 93
T82 13443-13449 http://purl.obolibrary.org/obo/CLO_0054251 denotes 2 > 93
T83 13443-13449 http://purl.obolibrary.org/obo/CLO_0054252 denotes 2 > 93
T84 13481-13482 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T85 13492-13496 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T86 13492-13496 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T87 13704-13705 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 13889-13894 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T89 13954-13955 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 14000-14001 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T91 14227-14228 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 14305-14310 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T93 14587-14592 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T94 14879-14884 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T95 15283-15284 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 15314-15315 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T97 15858-15861 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T98 16265-16266 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 16307-16308 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T100 16385-16389 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T101 16385-16389 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T102 16582-16587 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T103 17096-17101 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T104 17834-17839 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T105 18074-18079 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T106 18305-18308 http://purl.obolibrary.org/obo/CLO_0050154 denotes a 8
T107 18461-18466 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T108 18847-18850 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T109 18964-18965 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 19136-19141 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T111 19243-19266 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T112 19359-19360 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T113 19385-19386 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T114 19648-19652 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T115 19648-19652 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T116 19776-19781 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T117 20277-20282 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T118 20504-20509 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T119 20606-20607 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 20823-20824 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T121 20915-20916 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T122 21056-21061 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T123 21138-21142 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T124 21624-21629 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T125 21763-21771 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T126 21794-21795 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 21820-21821 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 22083-22087 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T129 22083-22087 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T130 22192-22197 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T131 22255-22260 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T132 22429-22434 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T133 22440-22444 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T134 22492-22496 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T135 22525-22533 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T136 22677-22678 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 22751-22756 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T138 22831-22832 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T139 22893-22894 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T140 23359-23364 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T141 23424-23425 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T142 23471-23472 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T143 23637-23642 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T144 23733-23738 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T145 23955-23956 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 23996-23998 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T147 24008-24009 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T148 24045-24047 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T149 24090-24092 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T150 24135-24137 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T151 24567-24568 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 24828-24829 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T153 24899-24900 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T154 24921-24924 http://purl.obolibrary.org/obo/CLO_0001577 denotes a 3
T155 25077-25082 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T156 25482-25488 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T157 25617-25622 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T158 25682-25683 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 25695-25700 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T160 25735-25736 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T161 26103-26106 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T162 26157-26158 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T163 26215-26216 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 26506-26511 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T165 26574-26578 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T166 26574-26578 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T167 26698-26703 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T168 27201-27206 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T169 27258-27259 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T170 27292-27293 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T171 27434-27439 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T172 27543-27552 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Humanized
T173 27605-27613 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T174 27770-27773 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T175 27904-27909 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T176 28025-28029 http://purl.obolibrary.org/obo/CLO_0001550 denotes a 10
T177 28161-28166 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T178 28421-28424 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T179 28598-28603 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T180 28663-28664 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T181 28710-28711 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T182 28938-28943 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T183 29111-29124 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin 6
T184 29225-29230 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T185 29571-29576 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T186 29806-29811 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T187 29871-29872 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T188 29917-29918 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T189 30334-30339 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T190 30633-30638 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T191 30750-30755 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T192 31261-31274 http://purl.obolibrary.org/obo/PR_000001091 denotes interleukin 1
T193 31370-31378 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T194 31370-31378 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T195 31570-31582 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T7 823-828 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T8 847-852 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T9 1230-1236 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T10 1325-1331 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T11 1619-1623 Chemical denotes PEEP http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683
T13 1652-1657 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T14 1708-1714 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T15 2149-2165 Chemical denotes antiviral agents http://purl.obolibrary.org/obo/CHEBI_22587
T16 2263-2268 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T17 2366-2385 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T19 2375-2385 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T20 2392-2401 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T21 2502-2512 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T22 2722-2733 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T23 2738-2748 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T24 2867-2878 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T25 2882-2891 Chemical denotes zanamivir http://purl.obolibrary.org/obo/CHEBI_50663
T26 2994-3005 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T27 3006-3024 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T28 3077-3095 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T29 3181-3185 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T30 3694-3712 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T31 3829-3834 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T32 3992-4010 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T33 4164-4175 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T34 4249-4259 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T35 4714-4727 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T36 5069-5088 Chemical denotes antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_33281
T37 5142-5152 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T38 5296-5304 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T39 5407-5421 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T40 5568-5582 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T41 5872-5887 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T42 6159-6166 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T43 6236-6243 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T44 6454-6465 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T45 6553-6558 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T46 6923-6928 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T47 6936-6947 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T48 7521-7538 Chemical denotes enzyme inhibitors http://purl.obolibrary.org/obo/CHEBI_23924
T49 7528-7538 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T50 7992-7998 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T51 8273-8282 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T52 8428-8439 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T53 8858-8876 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T54 9093-9111 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T55 9213-9224 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T56 9225-9243 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T57 9666-9676 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T58 9922-9937 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T59 10128-10135 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T60 10219-10233 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T61 10496-10515 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T62 10496-10505 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T63 10506-10515 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T64 10517-10521 Chemical denotes PEEP http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683
T66 10740-10763 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T67 10758-10763 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T68 10785-10790 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T69 11012-11021 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T70 11022-11031 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T71 11032-11041 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T72 11059-11077 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T74 11068-11077 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T75 11094-11110 Chemical denotes CYP3A4 inhibitor http://purl.obolibrary.org/obo/CHEBI_86501
T76 11101-11110 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T77 11123-11132 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T78 11155-11160 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T79 11175-11194 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T80 11175-11184 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T81 11185-11194 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T82 11272-11281 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T83 11282-11291 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T84 11843-11862 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T85 11843-11852 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T86 11853-11862 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T87 12071-12090 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T88 12071-12080 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T89 12081-12090 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T90 12095-12113 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T91 12151-12156 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T92 12270-12279 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T93 12284-12303 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T94 12284-12293 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T95 12294-12303 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T96 12357-12362 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T97 12480-12486 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T98 12523-12525 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T100 12588-12607 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T101 12588-12597 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T102 12598-12607 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T103 12612-12631 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T104 12612-12621 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T105 12622-12631 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T106 12637-12647 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T107 12680-12685 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T108 12810-12829 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T109 12810-12819 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T110 12820-12829 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T111 12834-12853 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T112 12834-12843 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T113 12844-12853 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T114 12859-12868 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T115 12874-12884 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T116 12885-12889 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T117 12925-12930 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T118 13091-13110 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T119 13091-13100 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T120 13101-13110 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T121 13115-13126 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T122 13131-13141 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T123 13194-13199 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T124 13475-13477 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T126 13545-13564 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T127 13545-13554 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T128 13555-13564 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T129 13798-13817 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T130 13798-13807 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T131 13808-13817 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T132 13821-13831 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T133 13835-13846 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T134 13889-13894 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T135 14133-14152 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T136 14133-14142 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T137 14143-14152 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T138 14157-14176 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T139 14157-14166 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T140 14167-14176 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T141 14263-14271 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T142 14305-14310 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T143 14428-14447 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T144 14428-14437 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T145 14438-14447 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T146 14461-14471 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T147 14481-14500 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T148 14481-14490 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T149 14491-14500 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T150 14514-14524 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T151 14587-14592 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T152 14710-14729 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T153 14710-14719 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T154 14720-14729 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T155 14743-14753 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T156 14763-14782 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T157 14763-14772 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T158 14773-14782 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T159 14796-14806 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T160 14879-14884 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T161 15010-15029 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T162 15010-15019 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T163 15020-15029 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T164 15035-15053 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T165 15058-15077 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T166 15058-15067 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T167 15068-15077 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T168 15083-15101 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T169 15107-15117 Chemical denotes levamisole http://purl.obolibrary.org/obo/CHEBI_6432
T170 15128-15138 Chemical denotes budesonide http://purl.obolibrary.org/obo/CHEBI_3207
T171 15144-15154 Chemical denotes formoterol http://purl.obolibrary.org/obo/CHEBI_5147
T172 15362-15381 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T173 15362-15371 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T174 15372-15381 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T175 15386-15404 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T176 15409-15417 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T177 15613-15632 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T178 15613-15622 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T179 15623-15632 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T180 15637-15655 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T181 15660-15679 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T182 15660-15669 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T183 15670-15679 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T184 15685-15695 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T185 15696-15700 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T186 15708-15718 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T187 15909-15928 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T188 15909-15918 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T189 15919-15928 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T190 15932-15942 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T191 15946-15957 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T192 15961-15979 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T193 15983-15994 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T194 16012-16024 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T195 16049-16068 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T196 16049-16058 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T197 16059-16068 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T198 16072-16082 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T199 16086-16097 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T200 16101-16119 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T201 16123-16134 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T202 16152-16164 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T203 16455-16465 Chemical denotes colchicine http://purl.obolibrary.org/obo/CHEBI_23359
T204 16483-16502 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T205 16483-16492 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T206 16493-16502 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T207 16582-16587 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T208 16702-16713 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T209 16719-16730 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T210 16735-16746 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T211 16752-16771 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T212 16752-16761 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T213 16762-16771 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T214 16810-16829 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T215 16810-16819 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T216 16820-16829 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T217 16835-16846 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T218 16851-16860 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T219 16861-16870 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T220 16876-16887 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T221 16892-16903 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T222 16909-16928 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T223 16909-16918 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T224 16919-16928 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T225 16933-16942 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T226 16943-16952 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T227 16958-16969 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T228 16975-16986 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T229 16991-17000 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T230 17001-17010 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T231 17016-17027 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T232 17033-17044 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T233 17096-17101 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T234 17220-17229 Chemical denotes Adenosine http://purl.obolibrary.org/obo/CHEBI_16335
T235 17349-17359 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T236 17556-17566 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T237 17757-17767 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T238 17834-17839 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T239 17926-17932 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T240 17995-18005 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T241 18074-18079 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T242 18174-18184 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T243 18356-18366 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T244 18371-18389 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T245 18394-18404 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T246 18410-18428 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T247 18461-18466 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T248 18602-18621 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T249 18602-18611 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T250 18612-18621 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T251 18626-18644 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T252 18649-18668 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T253 18649-18658 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T254 18659-18668 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T255 18674-18684 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T256 18685-18689 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T257 18697-18707 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T258 18882-18891 Chemical denotes Darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T259 18892-18902 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T260 18903-18912 Chemical denotes Darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T261 18930-18948 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T263 18939-18948 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T264 18966-18982 Chemical denotes CYP3A4 inhibitor http://purl.obolibrary.org/obo/CHEBI_86501
T265 18973-18982 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T266 18995-19004 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T267 19052-19061 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T268 19062-19072 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T269 19136-19141 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T270 19329-19353 Chemical denotes RNA polymerase inhibitor http://purl.obolibrary.org/obo/CHEBI_37416
T271 19344-19353 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T272 19452-19463 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T273 19500-19510 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T274 19582-19593 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T275 19683-19694 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T276 19699-19710 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T277 19715-19726 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T278 19732-19743 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T279 19776-19781 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T280 19883-19894 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T281 19900-19911 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T282 19916-19927 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T283 19933-19952 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T284 19933-19942 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T285 19943-19952 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T286 19991-20010 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T287 19991-20000 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T288 20001-20010 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T289 20016-20027 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T290 20032-20041 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T291 20042-20051 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T292 20057-20068 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T293 20073-20084 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T294 20090-20109 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T295 20090-20099 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T296 20100-20109 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T297 20114-20123 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T298 20124-20133 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T299 20139-20150 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T300 20156-20167 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T301 20172-20181 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T302 20182-20191 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T303 20197-20208 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T304 20214-20225 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T305 20277-20282 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T306 20406-20424 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T307 20430-20439 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T308 20440-20450 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T309 20504-20509 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T310 20675-20686 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T311 20692-20703 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T312 20708-20719 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T313 20991-21002 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T314 21056-21061 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T315 21125-21137 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T316 21133-21137 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T317 21230-21241 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T318 21247-21258 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T319 21263-21274 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T320 21280-21299 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T321 21280-21289 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T322 21290-21299 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T323 21338-21357 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T324 21338-21347 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T325 21348-21357 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T326 21363-21374 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T327 21379-21388 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T328 21389-21398 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T329 21404-21415 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T330 21420-21431 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T331 21437-21456 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T332 21437-21446 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T333 21447-21456 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T334 21461-21470 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T335 21471-21480 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T336 21486-21497 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T337 21503-21514 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T338 21519-21528 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T339 21529-21538 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T340 21544-21555 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T341 21561-21572 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T342 21624-21629 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T343 21779-21788 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T344 21887-21898 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T345 21935-21945 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T346 22017-22028 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T347 22118-22128 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T348 22192-22197 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T349 22306-22317 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T350 22319-22337 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T351 22408-22410 Chemical denotes Ph http://purl.obolibrary.org/obo/CHEBI_30396
T352 22576-22594 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T353 22751-22756 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T354 23025-23043 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T355 23048-23061 Chemical denotes ascorbic acid http://purl.obolibrary.org/obo/CHEBI_22652|http://purl.obolibrary.org/obo/CHEBI_29073
T357 23057-23061 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T358 23233-23244 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T359 23250-23268 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T360 23274-23286 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T361 23291-23302 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T362 23308-23326 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T363 23359-23364 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T364 23570-23588 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T365 23637-23642 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T366 23772-23790 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T367 23871-23881 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T368 24162-24180 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T369 24408-24427 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T370 24408-24417 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T371 24418-24427 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T372 24658-24676 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T373 24972-24982 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T374 24987-25005 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T375 25010-25020 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T376 25026-25044 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T377 25077-25082 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T378 25218-25237 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T379 25218-25227 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T380 25228-25237 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T381 25242-25260 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T382 25265-25273 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T383 25494-25512 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T384 25518-25530 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T385 25535-25553 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T386 25559-25571 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T387 25617-25622 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T388 25858-25877 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T389 25858-25867 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T390 25868-25877 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T391 25882-25900 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T392 25905-25924 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T393 25905-25914 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T394 25915-25924 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T395 25930-25940 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T396 25941-25945 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T397 25953-25963 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T398 26321-26336 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T399 26427-26445 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T400 26506-26511 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T401 26626-26644 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T402 26698-26703 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T403 26816-26821 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T404 26822-26832 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T405 26838-26856 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T406 26862-26872 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T407 26877-26888 Chemical denotes thalidomide http://purl.obolibrary.org/obo/CHEBI_9513
T408 26902-26907 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T409 26908-26918 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T410 26924-26942 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T411 26948-26958 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T412 27150-27168 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T413 27201-27206 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T414 27353-27355 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T416 27383-27401 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T417 27434-27439 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T418 27579-27590 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T419 27632-27634 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T421 27648-27650 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T423 27839-27850 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T424 27904-27909 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T425 28068-28079 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T426 28084-28095 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T427 28100-28111 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T428 28117-28128 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T429 28161-28166 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T430 28268-28279 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T431 28472-28483 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T432 28489-28507 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T433 28513-28525 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T434 28530-28541 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T435 28547-28565 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T436 28598-28603 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T437 28793-28804 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T438 28825-28836 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T439 28938-28943 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T440 29034-29045 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T441 29064-29075 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T442 29225-29230 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T443 29328-29334 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T444 29380-29391 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T445 29418-29420 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T447 29432-29442 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T448 29506-29517 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T449 29571-29576 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T450 29715-29734 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T451 29715-29724 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T452 29725-29734 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T453 29738-29748 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T454 29752-29763 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T455 29806-29811 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T456 30057-30059 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T458 30072-30074 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T460 30247-30257 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T461 30334-30339 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T462 30442-30453 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T463 30480-30482 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T465 30494-30504 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T466 30568-30579 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T467 30633-30638 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T468 30750-30755 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T469 30756-30761 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T470 30929-30934 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T471 31010-31020 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T472 31021-31032 Chemical denotes ruxolitinib http://purl.obolibrary.org/obo/CHEBI_66919
T473 31050-31061 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T474 31255-31257 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T476 31379-31385 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T477 31426-31432 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 5659-5671 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2 7594-7609 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T3 14013-14025 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T4 16390-16402 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T5 19267-19277 http://purl.obolibrary.org/obo/GO_0046903 denotes secretions
T6 21763-21778 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T7 22440-22451 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T8 22440-22451 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T9 22440-22451 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T10 22440-22451 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T11 22475-22488 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T12 29930-29942 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T25 0-226 Sentence denotes Members of a panel of 17 experts from the Italian Society of Anti-infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) were selected; they developed a list of 8 practical therapeutic questions to be addressed.
T26 227-526 Sentence denotes The members of the panel (which included infectious diseases specialists and pneumonologists) were divided into small groups and asked to summarize the available literature and their frontline-based opinion in brief (500 words maximum) narrative answers, plus a conclusive statement for each answer.
T27 527-647 Sentence denotes All the answers and statements were ultimately reviewed and discussed by the entire panel until a consensus was reached.
T28 648-728 Sentence denotes A brief summary of questions and conclusive statements is available in Table 1 .
T29 729-904 Sentence denotes Table 2 summarizes available or ongoing randomized controlled trial (RCT) information for off-label/compassionate-use drugs mostly used for the treatment of COVID-19 patients.
T30 905-1135 Sentence denotes Of note, we focused on pneumologic and anti-infective/anti-inflammatory treatments; the discussion of the therapeutic approach to COVID-19–related cardiovascular/coagulative disorders is outside the scope of this narrative review.
T31 1136-1179 Sentence denotes Table 1 Summary of questions and statements
T32 1180-1198 Sentence denotes Question Statement
T33 1199-1210 Sentence denotes Question 1.
T34 1211-1310 Sentence denotes How to use at best oxygen therapy and noninvasive mechanical ventilation for preventing intubation?
T35 1311-1505 Sentence denotes Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%.
T36 1506-1810 Sentence denotes Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion).
T37 1811-1893 Sentence denotes However, no clear indications/criteria can be provided pending further experience.
T38 1894-2129 Sentence denotes Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation.
T39 2130-2141 Sentence denotes Question 2.
T40 2142-2182 Sentence denotes Should antiviral agents be administered?
T41 2183-2313 Sentence denotes At the present time, evidence from the first published RCT does not support off-label treatment with LPV/RTV in COVID-19 patients.
T42 2314-2458 Sentence denotes This result should also discourage the use of other protease inhibitors (e.g. darunavir), at least until results of dedicated RCT are available.
T43 2459-2681 Sentence denotes Although promising in preclinical studies, remdesivir should be currently provided to COVID-19 patients only within RCT (preferentially) or compassionate-use/expanded-access programmes, owing to its investigational nature.
T44 2682-2866 Sentence denotes Pending high-level supporting evidence, favipiravir and umifenovir should not be provided an outside RCT, at least in those countries where they are not approved for other indications.
T45 2867-2974 Sentence denotes Oseltamivir or zanamivir should be provided only in the presence of suspected/proven concomitant influenza.
T46 2975-2986 Sentence denotes Question 3.
T47 2987-3041 Sentence denotes Should chloroquine/hydroxychloroquine be administered?
T48 3042-3291 Sentence denotes Pending results of RCT, the use of hydroxychloroquine may be considered for treating worsening patients with COVID-19 only if no important drug interactions can be anticipated and with close monitoring of hepatic, renal function and QT prolongation.
T49 3292-3501 Sentence denotes This is based on its activity in vitro against SARS-CoV-2 (although weak) and on the availability of low-level clinical evidence of anticipation of virus clearance from a small controlled, nonrandomized study.
T50 3502-3674 Sentence denotes However, it should also be kept in mind that the study was highly susceptible to bias and there are still no data regarding hard clinical endpoints such as crude mortality.
T51 3675-3799 Sentence denotes For these reasons, hydroxychloroquine should be preferentially administered within the framework of investigational studies.
T52 3800-3909 Sentence denotes When this is unfeasible, off-label use may be considered according to local protocols and consent procedures.
T53 3910-4106 Sentence denotes In view of the absence of evidence, we are currently unable to support the use of hydroxychloroquine in asymptomatic or mildly symptomatic nonhospitalized patients outside investigational studies.
T54 4107-4144 Sentence denotes The same applies to prophylactic use.
T55 4145-4156 Sentence denotes Question 4.
T56 4157-4192 Sentence denotes Should antibiotics be administered?
T57 4193-4375 Sentence denotes In our opinion, it might be prudent to consider empiric antibiotic treatment in critically ill patients with pneumonia due to COVID-19 in whom bacterial infection cannot be excluded.
T58 4376-4613 Sentence denotes This suggestion is based on the fact that bacterial coinfection (a) is common in patients with viral pneumonia and (b) can be associated with a substantial risk of delaying appropriate treatment, thereby potentially increasing mortality.
T59 4614-4861 Sentence denotes Because of the limited available data on both the microbiologic epidemiology (and the prevalence of antimicrobial resistance) of bacterial superinfections in COVID-19 patients, it is difficult to provide specific pathogen-oriented recommendations.
T60 4862-5276 Sentence denotes Therefore, pending further studies, we suggest to empirically treat COVID-19 patients according to their clinical syndrome (e.g. community-acquired pneumonia, hospital-acquired pneumonia), choosing the best antimicrobial agent or agents on the basis of local guidelines and local antibiotic susceptibility patterns, with early de-escalation or discontinuation according to microbiology results, whenever available.
T61 5277-5288 Sentence denotes Question 5.
T62 5289-5321 Sentence denotes Should steroids be administered?
T63 5322-5475 Sentence denotes So far, no definitive efficacy or effectiveness data are available on the benefit of corticosteroid administration in patients with SARS-CoV-2 infection.
T64 5476-5619 Sentence denotes As the WHO underlines, there is an important need for efficacy data from RCT for supporting corticosteroid therapy in patients with SARS-Cov-2.
T65 5620-6066 Sentence denotes However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission).
T66 6067-6299 Sentence denotes Yet in the absence of convincing evidence, the following cannot currently be supported: (1) steroid administration stratified according to inflammatory markers; and (b) steroid administration in non–critically ill COVID-19 patients.
T67 6300-6311 Sentence denotes Question 6.
T68 6312-6393 Sentence denotes Should other immunosuppressive and/or immunomodulatory therapies be administered?
T69 6394-6548 Sentence denotes Owing to the lack of high-level evidence, administration of tocilizumab to patients with COVID-19 should preferentially occur within the framework of RCT.
T70 6549-6875 Sentence denotes Off-label use according to local protocols and consent procedures may be considered only in those COVID-19 patients excluded from RCT (or hospitalized where RCT are not available or still to be implemented) and who are worsening while receiving standard supportive care (in the absence of concomitant/superimposed infections).
T71 6876-7345 Sentence denotes In our opinion, this could be a reasonable off-label use of tocilizumab in these early phases of the COVID-19 pandemic, although patients and physicians should be aware that currently there is only a non–peer-reviewed, noncomparative, observational experience (very low evidence from an unreviewed cases series) and that it only supports a potential favourable effect on inflammatory signs and symptoms, while there is no information on any possible effect on survival.
T72 7346-7551 Sentence denotes In the absence of clinical studies, we suggest to preferentially administer also other immunosuppressive and/or immunomodulatory therapies (e.g. anakinra, Janus kinase family enzyme inhibitors) within RCT.
T73 7552-7870 Sentence denotes This also applies to modifications of the immune response through high-dose intravenous immunoglobulins or plasma from convalescent patients, which, although promising in small case series, both deserve dedicated RCT investigation to clearly understand their role in impacting COVID-19 outcomes and their tolerability.
T74 7871-7882 Sentence denotes Question 7.
T75 7883-7934 Sentence denotes What is the optimal timing of treatment initiation?
T76 7935-8230 Sentence denotes Supportive therapy (symptomatic therapy, rehydration and oxygen supplementation, if necessary), should be initiated as soon as the patient manifests respiratory or systemic symptoms, including severe asthenia, high fever, persistent cough and/or clinical or radiologic signs of lung involvement.
T77 8231-8501 Sentence denotes Pending further evidence, in our opinion, antiviral treatments should not be provided to patients with SARS-CoV-2 infection outside RCT or compassionate-use programmes (with the exception of early oseltamivir initiation in patients with suspected concomitant influenza).
T78 8502-8773 Sentence denotes Corticosteroids should be provided early in well-defined categories of patients (patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections), while their role in other COVID-19 patients still remains uncertain.
T79 8774-9160 Sentence denotes Although based on low-level evidence and pending RCT results, in our opinion, early hydroxychloroquine administration may be considered in COVID-19 patients manifesting moderate to severe symptoms, whereas further data are needed to better delineate the true balance between possible favourable effects and toxicity of hydroxychloroquine in mildly symptomatic and asymptomatic patients.
T80 9161-9172 Sentence denotes Question 8.
T81 9173-9212 Sentence denotes What is the optimal treatment duration?
T82 9213-9512 Sentence denotes Chloroquine/hydroxychloroquine treatment should be continued for at least 5 days, and possibly up to 20 days, according to some expert opinions, although it should be noted that data regarding the relative safety of different lengths of administration in COVID-19 patients are currently unavailable.
T83 9513-9640 Sentence denotes Early discontinuation should be considered in the presence of adverse effects (e.g. QT prolongation or hepatic/renal toxicity).
T84 9641-9918 Sentence denotes If the administration of remdesivir is approved within compassionate-use/expanded-access programmes, treatment duration should follow compassionate or expanded access protocols (e.g. up to 10 days according to the most recent compassionate protocol at the time of this review).
T85 9919-10036 Sentence denotes If corticosteroids are provided, we suggest a total treatment duration of 7–10 days, with progressive dose reduction.
T86 10037-10307 Sentence denotes If the patient's condition deteriorates with worsening lung physiology after withdrawal of steroid treatment in the absence of bacterial or fungal superinfection, a second course of corticosteroid treatment may be considered, followed by slow tapering after improvement.
T87 10308-10683 Sentence denotes ARDS, acute respiratory distress syndrome; COVID-19, coronavirus disease 2019; CPAP, continuous positive airway pressure; HFNC, high-flow nasal cannula; ICU, intensive care unit; LPV/RTV, lopinavir/ritonavir; PEEP, positive end expiratory pressure; RCT, randomized controlled trial; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; WHO, World Health Organization.
T88 10684-10859 Sentence denotes Table 2 Available and ongoing RCT on anti-infective and anti-inflammatory drugs most provided as off-label/compassionate treatments in the first phase of the COVID-19 pandemic
T89 10860-11011 Sentence denotes Drug Class/mechanism Published RCT Ongoing RCT for treatment/prevention of COVID-19 (recruiting or not yet recruiting) registered at ClinicalTrials.gov
T90 11012-11078 Sentence denotes Lopinavir/ritonavir Lopinavir is an HIV type 1 protease inhibitor.
T91 11079-11271 Sentence denotes Ritonavir is a CYP3A4 inhibitor that boosts lopinavir concentrations • Open-label RCT comparing lopinavir/ritonavir (99 patients) vs. standard of care (100) in patients with COVID-19 in China.
T92 11272-11349 Sentence denotes Lopinavir/ritonavir was administered at the dosage of 400/100 mg for 14 days.
T93 11350-11429 Sentence denotes The primary time-to-event endpoint was clinical improvement from randomization.
T94 11430-11818 Sentence denotes In the primary study population (ITT), no statistically significant differences were observed with regard to the primary endpoint of clinical improvement (HR 1.24 with standard of care as reference, 95% CI 0.90 to 1.72) and the secondary endpoint of 28-day mortality (19.2% vs. 25.0% in investigational and comparator arms, respectively; percentage difference −5.8%, 95% CI −17.3 to 5.7).
T95 11819-11972 Sentence denotes In the mITT population, lopinavir/ritonavir led to a median time to clinical improvement that was shorter by 1 day than that observed with standard care.
T96 11973-12145 Sentence denotes Median time between symptoms onset and randomization was 13 days (IQR 11–16) [22] • Comparison of lopinavir/ritonavir vs. hydroxychloroquine in patients with mild COVID-19.
T97 12146-12187 Sentence denotes Open-label RCT (NCT04307693, recruiting).
T98 12188-12247 Sentence denotes Primary endpoint: virus load at day 3, 5, 7, 10, 14 and 18.
T99 12248-12351 Sentence denotes • Comparison of ASC09/ritonavir vs. lopinavir/ritonavir in patients with confirmed COVID-19 pneumoniae.
T100 12352-12401 Sentence denotes Open-label RCT (NCT04261907, not yet recruiting).
T101 12402-12571 Sentence denotes Primary endpoint: adverse outcome at day 14 (composite of Spo 2 ≤ 93% without oxygen supplementation, PaO2/FiO2 ≤ 300 mm Hg or respiratory rate ≥ 30 breaths per minute).
T102 12572-12674 Sentence denotes • Comparison of lopinavir/ritonavir vs. lopinavir/ritonavir plus umifenovir in patients with COVID-19.
T103 12675-12716 Sentence denotes Open-label RCT (NCT04252885, recruiting).
T104 12717-12793 Sentence denotes Primary endpoint: rate of virus inhibition at day 0, 2, 4, 7, 10, 14 and 21.
T105 12794-12919 Sentence denotes • Comparison of lopinavir/ritonavir vs. lopinavir/ritonavir plus ribavirin plus interferon beta 1b in patients with COVID-19.
T106 12920-12961 Sentence denotes Open-label RCT (NCT04276688, recruiting).
T107 12962-13044 Sentence denotes Primary endpoint: time to negative nasopharyngeal swab RT-PCR (follow-up 30 days).
T108 13045-13188 Sentence denotes • Comparison of only supportive treatment vs. lopinavir/ritonavir vs. oseltamivir vs. umifenovir in patients with confirmed COVID-19 pneumonia.
T109 13189-13230 Sentence denotes Open-label RCT (NCT04255017, recruiting).
T110 13231-13506 Sentence denotes Primary endpoints: (a) rate of disease remission (mild disease: fever, cough and other symptoms relieved with improved lung CT; severe disease: fever, cough and other symptoms relieved with improved lung CT, Spo 2 > 93% or Pao 2/Fio 2 > 300 mm Hg); (b) time to lung recovery.
T111 13507-13619 Sentence denotes • Comparison of chemoprophylaxis with lopinavir/ritonavir vs. placebo in healthcare workers exposed to COVID-19.
T112 13620-13671 Sentence denotes Double-blind RCT (NCT04328285, not yet recruiting).
T113 13672-13766 Sentence denotes Primary endpoint: occurrence of a symptomatic or asymptomatic COVID-19 (follow-up 2.5 months).
T114 13767-13883 Sentence denotes • Comparison of carrimycin vs. lopinavir/ritonavir or umifenovir or chloroquine in patients with COVID-19 pneumonia.
T115 13884-13933 Sentence denotes Open-label RCT (NCT04286503, not yet recruiting).
T116 13934-14116 Sentence denotes Primary endpoints: (a) fever to normal time (follow-up 30 days); (b) pulmonary inflammation resolution time (follow-up 30 days); (c) negative conversion of throat swab RT-PCR at EOT.
T117 14117-14299 Sentence denotes • Comparison of lopinavir/ritonavir vs. lopinavir/ritonavir plus xiyanping (injectable component derived from a plant used in traditional Chinese medicine) in patients with COVID-19.
T118 14300-14349 Sentence denotes Open-label RCT (NCT04295551, not yet recruiting).
T119 14350-14411 Sentence denotes Primary endpoint: clinical recovery time (follow-up 28 days).
T120 14412-14581 Sentence denotes • Comparison of lopinavir/ritonavir plus inhaled interferon alfa vs. lopinavir/ritonavir plus inhaled interferon alfa plus xiyanping injection in patients with COVID-19.
T121 14582-14631 Sentence denotes Open-label RCT (NCT04275388, not yet recruiting).
T122 14632-14693 Sentence denotes Primary endpoint: clinical recovery time (follow-up 14 days).
T123 14694-14873 Sentence denotes • Comparison of lopinavir/ritonavir plus inhaled interferon alfa vs. lopinavir/ritonavir plus inhaled interferon alfa plus traditional Chinese medicines in patients with COVID-19.
T124 14874-14915 Sentence denotes Open-label RCT (NCT04251871, recruiting).
T125 14916-14993 Sentence denotes Primary endpoint: time to complete remission of symptoms (follow-up 28 days).
T126 14994-15209 Sentence denotes • Comparison of lopinavir/ritonavir plus hydroxychloroquine vs. lopinavir/ritonavir plus hydroxychloroquine plus levamisole pill plus budesonide plus formoterol inhaler in patients with nonsevere COVID-19 pneumonia.
T127 15210-15263 Sentence denotes Partly blinded RCT (NCT04331470, not yet recruiting).
T128 15264-15345 Sentence denotes Primary endpoint: (a) clear CT scan at 3–7 days; (b) negative RT-PCR at 3–7 days.
T129 15346-15457 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. losartan vs. placebos in patients with COVID-19.
T130 15458-15519 Sentence denotes Double-blind, adaptive RCT (NCT04328012, not yet recruiting).
T131 15520-15596 Sentence denotes Primary endpoint: NIAID COVID-19 ordinal severity scale (follow-up 60 days).
T132 15597-15766 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta 1a vs. remdesivir vs. standard of care in patients with COVID-19.
T133 15767-15820 Sentence denotes Double-blind, adaptive RCT (NCT04315948, recruiting).
T134 15821-15892 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 15.
T135 15893-16192 Sentence denotes • Comparison of lopinavir/ritonavir or umifenovir or chloroquine or hydroxychloroquine or oseltamivir (with or without azithromycin) vs. natural honey plus lopinavir/ritonavir or umifenovir or chloroquine or hydroxychloroquine or oseltamivir (with or without azithromycin) in patients with COVID-19.
T136 16193-16244 Sentence denotes Single-blind RCT (NCT04323345, not yet recruiting).
T137 16245-16438 Sentence denotes Primary endpoints: (a) positive to negative swabs at day 14; (b) fever to normal temperature in days (follow-up 14 days); (c) resolution of lung inflammation in CT or X-ray (follow-up 30 days).
T138 16439-16576 Sentence denotes • Comparison of colchicine (with or without lopinavir/ritonavir) vs. local standard of care in patients with moderate to severe COVID-19.
T139 16577-16626 Sentence denotes Open-label RCT (NCT04328480, not yet recruiting).
T140 16627-16685 Sentence denotes Primary endpoint: all-cause mortality (follow-up 30 days).
T141 16686-17090 Sentence denotes • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19.
T142 17091-17140 Sentence denotes Open-label RCT (NCT04303299, not yet recruiting).
T143 17141-17208 Sentence denotes Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks).
T144 17209-17239 Sentence denotes Remdesivir Adenosine analogue.
T145 17240-17405 Sentence denotes It binds to RNA-dependent RNA polymerase and acts as an RNA-chain terminator • Not available • Comparison of remdesivir vs. placebo in patients with severe COVID-19.
T146 17406-17449 Sentence denotes Double-blind RCT (NCT04257656, recruiting).
T147 17450-17539 Sentence denotes Primary endpoint: clinical status, assessed by an ordinal scale at days 7, 14, 21 and 28.
T148 17540-17622 Sentence denotes • Comparison of remdesivir vs. placebo in patients with mild to moderate COVID-19.
T149 17623-17666 Sentence denotes Double-blind RCT (NCT04252664, recruiting).
T150 17667-17740 Sentence denotes Primary endpoint: time to clinical recovery in hours (follow-up 28 days).
T151 17741-17828 Sentence denotes • Comparison of remdesivir vs. local standard of care in patients with severe COVID-19.
T152 17829-17870 Sentence denotes Open-label RCT (NCT04252664, recruiting).
T153 17871-17978 Sentence denotes Primary endpoint: composite of fever normalization and oxygen saturation normalization (follow-up 14 days).
T154 17979-18068 Sentence denotes • Comparison of remdesivir vs. local standard of care in patients with moderate COVID-19.
T155 18069-18110 Sentence denotes Open-label RCT (NCT04292730, recruiting).
T156 18111-18157 Sentence denotes Primary endpoint: discharged status at day 14.
T157 18158-18223 Sentence denotes • Comparison of remdesivir vs. placebo in patients with COVID-19.
T158 18224-18267 Sentence denotes Double-blind RCT (NCT04280705, recruiting).
T159 18268-18339 Sentence denotes Primary endpoint: severity rating on a 8-point ordinal scale at day 15.
T160 18340-18455 Sentence denotes • Comparison of remdesivir vs. hydroxychloroquine vs. remdesivir plus hydroxychloroquine in patients with COVID-19.
T161 18456-18514 Sentence denotes Open-label adaptive RCT (NCT04321616, not yet recruiting).
T162 18515-18585 Sentence denotes Primary endpoint: all-cause in-hospital mortality (follow-up 3 weeks).
T163 18586-18755 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta 1a vs. remdesivir vs. standard of care in patients with COVID-19.
T164 18756-18809 Sentence denotes Double-blind, adaptive RCT (NCT04315948, recruiting).
T165 18810-18881 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 15.
T166 18882-18949 Sentence denotes Darunavir/cobicistat Darunavir is an HIV type 1 protease inhibitor.
T167 18950-19130 Sentence denotes Cobicistat is a CYP3A4 inhibitor that boosts darunavir concentrations • Not available • Comparison of darunavir/cobicistat vs. standard of care in patients with COVID-19 pneumonia.
T168 19131-19172 Sentence denotes Open-label RCT (NCT04252274, recruiting).
T169 19173-19287 Sentence denotes Primary endpoint: virologic clearance rate of throat swabs, sputum or lower respiratory tract secretions at day 7.
T170 19288-19594 Sentence denotes Favipiravir Anti-influenza RNA-dependent RNA polymerase inhibitor • In a recent RCT published on a preprint server and comparing 120 COVID-19 patients treated with favipiravir vs. 120 COVID-19 patients receiving umifenovir, higher rates of clinical recovery were observed in patients receiving favipiravir.
T171 19595-19770 Sentence denotes The manuscript is publicly available but still to be peer reviewed [30] • Comparison of favipiravir vs. tocilizumab vs. favipiravir plus tocilizumab in patients with COVID-19.
T172 19771-19812 Sentence denotes Open-label RCT (NCT04310228, recruiting).
T173 19813-19866 Sentence denotes Primary endpoint: clinical cure (follow-up 3 months).
T174 19867-20271 Sentence denotes • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19.
T175 20272-20321 Sentence denotes Open-label RCT (NCT04303299, not yet recruiting).
T176 20322-20389 Sentence denotes Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks).
T177 20390-20498 Sentence denotes • Comparison of hydroxychloroquine plus darunavir/cobicistat vs. standard of care in patients with COVID-19.
T178 20499-20540 Sentence denotes Open-label RCT (NCT04304053, recruiting).
T179 20541-20658 Sentence denotes Primary endpoint: incidence of secondary cases among contacts of a case and contacts of contacts (follow-up 14 days).
T180 20659-20758 Sentence denotes • Comparison of chloroquine plus favipiravir vs. favipiravir vs. placebo in patients with COVID-19.
T181 20759-20802 Sentence denotes Double-blind RCT (NCT04319900, recruiting).
T182 20803-20974 Sentence denotes Primary endpoints: (a) time to improvement/recovery and frequency of improvement/recovery (follow-up 10 days); (b) time to negative swab/sputum RT-PCR (follow-up 10 days).
T183 20975-21050 Sentence denotes • Comparison of favipiravir vs. standard of care in patients with COVID-19.
T184 21051-21100 Sentence denotes Open-label RCT (NCT04333589, not yet recruiting).
T185 21101-21213 Sentence denotes Primary endpoint: viral nucleic acid test negative conversion rate in nasopharyngeal swabs (follow-up 5 months).
T186 21214-21618 Sentence denotes • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19.
T187 21619-21668 Sentence denotes Open-label RCT (NCT04303299, not yet recruiting).
T188 21669-21736 Sentence denotes Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks).
T189 21737-22029 Sentence denotes Umifenovir Anti-influenza membrane fusion inhibitor • In a recent RCT published on a preprint server and comparing 120 COVID-19 patients treated with favipiravir vs. 120 COVID-19 patients receiving umifenovir, higher rates of clinical recovery were observed in patients receiving favipiravir.
T190 22030-22186 Sentence denotes The manuscript is publicly available but still to be peer reviewed [30] • Comparison of umifenovir vs. standard of care in patients with COVID-19 pneumonia.
T191 22187-22236 Sentence denotes Open-label RCT (NCT04260594, not yet recruiting).
T192 22237-22305 Sentence denotes Primary endpoint: virus negative conversion rate (follow-up 7 days).
T193 22306-22685 Sentence denotes Chloroquine, hydroxychloroquine Some proposed mechanisms are the following: increase in the endosomal Ph necessary for the virus/host cell fusion; interference with the glycosylation of cell receptors; immunomodulatory activity • Not available • Comparison of different hydroxychloroquine dosages vs. placebo in three cohorts (outpatients, inpatients, healthcare workers a risk).
T194 22686-22810 Sentence denotes Double-blind RCT for outpatients and healthcare workers and open-label RCT for inpatients (NCT04329923, not yet recruiting).
T195 22811-23008 Sentence denotes Primary endpoints: (a) release from quarantine (outpatients, follow-up 14 days); (b) discharge (inpatients, follow-up 14 days); (c) development of COVID-19 (healthcare workers, follow-up 2 months).
T196 23009-23095 Sentence denotes • Comparison of hydroxychloroquine vs. ascorbic acid in contacts of COVID-19 patients.
T197 23096-23147 Sentence denotes Double-blind RCT (NCT04328961, not yet recruiting).
T198 23148-23216 Sentence denotes Primary endpoint: laboratory-confirmed COVID-19 (follow-up 14 days).
T199 23217-23353 Sentence denotes • Comparison of tocilizumab plus hydroxychloroquine plus azithromycin vs. tocilizumab plus hydroxychloroquine in patients with COVID-19.
T200 23354-23403 Sentence denotes Open-label RCT (NCT04332094, not yet recruiting).
T201 23404-23631 Sentence denotes Primary endpoints: (a) in-hospital mortality (follow-up 2 weeks); (b) need for mechanical ventilation in the ICU (follow-up 2 weeks).• Comparison of ciclesonide plus hydroxychloroquine vs. ciclesonide in patients with COVID-19.
T202 23632-23681 Sentence denotes Open-label RCT (NCT04330586, not yet recruiting).
T203 23682-23755 Sentence denotes Primary endpoint: SARS-CoV-2 eradication (based on virus load) at day 14.
T204 23756-23882 Sentence denotes • Comparison of hydroxychloroquine vs. placebo in patients with COVID-19 and under biological treatment and/or JAK inhibitors.
T205 23883-23934 Sentence denotes Double-blind RCT (NCT04330495, not yet recruiting).
T206 23935-24145 Sentence denotes Primary endpoints: (a) incidence rate of COVID-19 (follow-up 27 weeks); (b) prevalence of COVID-19 (follow-up 27 weeks); (c) case fatality rate (follow-up 27 weeks); (d) ICU admission rate (follow-up 27 weeks).
T207 24146-24254 Sentence denotes • Comparison of hydroxychloroquine vs. placebo for the prevention of COVID-19 in healthcare workers at risk.
T208 24255-24306 Sentence denotes Double-blind RCT (NCT04328467, not yet recruiting).
T209 24307-24369 Sentence denotes Primary endpoint: prevalence of COVID-19 (follow-up 12 weeks).
T210 24370-24482 Sentence denotes • Comparison of chemoprophylaxis with lopinavir/ritonavir vs. placebo in healthcare workers exposed to COVID-19.
T211 24483-24534 Sentence denotes Double-blind RCT (NCT04328285, not yet recruiting).
T212 24535-24552 Sentence denotes Primary endpoint:
T213 24553-24641 Sentence denotes Occurrence of a symptomatic or asymptomatic SARS-CoV-2 infection (follow-up 2.5 months).
T214 24642-24763 Sentence denotes • Comparison of hydroxychloroquine vs. placebo in symptomatic COVID-19 patients or exposed healthcare workers/households.
T215 24764-24807 Sentence denotes Double-blind RCT (NCT04308668, recruiting).
T216 24808-24955 Sentence denotes Primary endpoints: (a) incidence of symptomatic COVID-19 among asymptomatic participants; (b) severity rating on a 3-point ordinal scale at day 14.
T217 24956-25071 Sentence denotes • Comparison of remdesivir vs. hydroxychloroquine vs. remdesivir plus hydroxychloroquine in patients with COVID-19.
T218 25072-25130 Sentence denotes Open-label adaptive RCT (NCT04321616, not yet recruiting).
T219 25131-25201 Sentence denotes Primary endpoint: all-cause in-hospital mortality (follow-up 3 weeks).
T220 25202-25313 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. losartan vs. placebos in patients with COVID-19.
T221 25314-25375 Sentence denotes Double-blind, adaptive RCT (NCT04328012, not yet recruiting).
T222 25376-25452 Sentence denotes Primary endpoint: NIAID COVID-19 Ordinal Severity Scale (follow-up 60 days).
T223 25453-25611 Sentence denotes • Comparison of convalescent plasma plus hydroxychloroquine plus azithromycin vs. hydroxychloroquine plus azithromycin in hospitalized patients with COVID-19.
T224 25612-25661 Sentence denotes Open-label RCT (NCT04332835, not yet recruiting).
T225 25662-25841 Sentence denotes Primary endpoints: (a) change in virus load at days 0, 4, 7, 14 and 28; (b) change in IgM COVID-19 titers at days 0, 4, 7, 14 and 28; (c) change in IgG at days 0, 4, 7, 14 and 28.
T226 25842-26011 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta-1a vs. remdesivir vs. standard of care in patients with COVID-19.
T227 26012-26065 Sentence denotes Double-blind, adaptive RCT (NCT04315948, recruiting).
T228 26066-26137 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 15.
T229 26138-26500 Sentence denotes Methylprednisolone A subgroup of patients with severe COVID-19 might develop a cytokine storm syndrome which causes rapidly progressive pneumonia, ARDS and clinical deterioration and corticosteroids administration may halt the dysregulated cytokine release • Not available • Comparison of methylprednisolone vs. standard of care in patients with severe COVID-19.
T230 26501-26542 Sentence denotes Open-label RCT (NCT04244591, recruiting).
T231 26543-26609 Sentence denotes Primary endpoint: lower Murray lung injury score at days 7 and 14.
T232 26610-26692 Sentence denotes • Comparison of methylprednisolone vs. standard of care in patients with COVID-19.
T233 26693-26734 Sentence denotes Open-label RCT (NCT04273321, recruiting).
T234 26735-26791 Sentence denotes Primary endpoint: treatment failure (follow-up 14 days).
T235 26792-26992 Sentence denotes • Comparison of inhaled alpha interferon plus methylprednisolone plus umifenovir vs. thalidomide plus inhaled alpha interferon plus methylprednisolone plus umifenovir in patients with severe COVID-19.
T236 26993-27044 Sentence denotes Double-blind RCT (NCT04273581, not yet recruiting).
T237 27045-27112 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 28 days).
T238 27113-27195 Sentence denotes • Comparison of different dosages of methylprednisolone in patients with COVID-19.
T239 27196-27237 Sentence denotes Open-label RCT (NCT04263402, recruiting).
T240 27238-27319 Sentence denotes Primary endpoints: (a) disease readmission at day 7; (b) critical stage at day 7.
T241 27320-27428 Sentence denotes • Comparison of siltuximab (anti–IL-6 monoclonal antibody) vs. methylprednisolone in patients with COVID-19.
T242 27429-27478 Sentence denotes Open-label RCT (NCT04329650, not yet recruiting).
T243 27479-27530 Sentence denotes Primary endpoint: ICU admission (follow-up 29 days)
T244 27531-27647 Sentence denotes Tocilizumab Humanized monoclonal IgG1 antibody, tocilizumab inhibits both membrane-bound and soluble IL-6 receptors.
T245 27648-27898 Sentence denotes IL-6, is one of the main drivers of immunologic response and symptoms in patients with dysregulated cytokine release that has been observed in severe COVID-19 • Not available • Comparison of tocilizumab vs. standard of care in patients with COVID-19.
T246 27899-27948 Sentence denotes Open-label RCT (NCT04331808, not yet recruiting).
T247 27949-28051 Sentence denotes Primary endpoint: WHO progression scale at day 7 and 14 (severity rating on a 10-point ordinal scale).
T248 28052-28155 Sentence denotes • Comparison of favipiravir vs. tocilizumab vs. favipiravir plus tocilizumab in patients with COVID-19.
T249 28156-28197 Sentence denotes Open-label RCT (NCT04310228, recruiting).
T250 28198-28251 Sentence denotes Primary endpoint: clinical cure (follow-up 3 months).
T251 28252-28331 Sentence denotes • Comparison of tocilizumab vs. placebo in hospitalized patients with COVID-19.
T252 28332-28383 Sentence denotes Double-blind RCT (NCT04320615, not yet recruiting).
T253 28384-28455 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 28.
T254 28456-28592 Sentence denotes • Comparison of tocilizumab plus hydroxychloroquine plus azithromycin vs. tocilizumab plus hydroxychloroquine in patients with COVID-19.
T255 28593-28642 Sentence denotes Open-label RCT (NCT04332094, not yet recruiting).
T256 28643-28776 Sentence denotes Primary endpoints: (a) in-hospital mortality (follow-up 2 weeks); (b) need for mechanical ventilation in the ICU (follow-up 2 weeks).
T257 28777-28932 Sentence denotes • Comparison of chloroquine analog (GNS651) vs. tocilizumab vs. nivolumab vs. standard of care in patients with advanced or metastatic cancer and COVID-19.
T258 28933-28982 Sentence denotes Open-label RCT (NCT04333914, not yet recruiting).
T259 28983-29000 Sentence denotes Primary endpoint:
T260 29001-29017 Sentence denotes 28-day survival.
T261 29018-29219 Sentence denotes • Comparison of tocilizumab intravenously vs. tocilizumab subcutaneously vs. sarilumab (anti-interleukin 6 receptor α monoclonal antibody) subcutaneously vs. standard of care in patients with COVID-19.
T262 29220-29269 Sentence denotes Open-label RCT (NCT04322773, not yet recruiting).
T263 29270-29363 Sentence denotes Primary endpoint: time to independence from supplementary oxygen therapy (follow-up 28 days).
T264 29364-29565 Sentence denotes • Comparison of tocilizumab vs. anakinra (recombinant IL-1 receptor antagonist) vs. siltuximab vs. anakinra plus siltuximab vs. anakinra plus tocilizumab vs. standard of care in patients with COVID-19.
T265 29566-29615 Sentence denotes Open-label RCT (NCT04330638, not yet recruiting).
T266 29616-29683 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 15 days).
T267 29684-29800 Sentence denotes • Comparison of carrimycin vs. lopinavir/ritonavir or umifenovir or chloroquine in patients with COVID-19 pneumonia.
T268 29801-29850 Sentence denotes Open-label RCT (NCT04286503, not yet recruiting).
T269 29851-30033 Sentence denotes Primary endpoints: (a) fever to normal time (follow-up 30 days); (b) pulmonary inflammation resolution time (follow-up 30 days); (c) negative conversion of throat swab RT-PCR at EOT.
T270 30034-30071 Sentence denotes Anakinra Antagonist of IL-1 receptor.
T271 30072-30328 Sentence denotes IL-1 is one of the main drivers of immunologic response and symptoms in patients with cytokine-release syndrome. • Not available • Comparison of anakinra vs. emapalumab (anti–interferon γ monoclonal antibody) vs. standard of care in patients with COVID-19.
T272 30329-30378 Sentence denotes Open-label RCT (NCT04324021, not yet recruiting).
T273 30379-30425 Sentence denotes Primary endpoint: treatment success at day 15.
T274 30426-30627 Sentence denotes • Comparison of tocilizumab vs. anakinra (recombinant IL-1 receptor antagonist) vs. siltuximab vs. anakinra plus siltuximab vs. anakinra plus tocilizumab vs. standard of care in patients with COVID-19.
T275 30628-30677 Sentence denotes Open-label RCT (NCT04330638, not yet recruiting).
T276 30678-30745 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 15 days).
T277 30746-30879 Sentence denotes Off-label drugs mostly provided in Italy during the first phase of the COVID-19 pandemic according to the authors' direct experience.
T278 30880-31063 Sentence denotes Of note, there are also registered RCT for other drugs to be investigated in patients with COVID-19 (e.g. the Janus kinase family inhibitors ruxolitinib, baricitinib and tofacitinib).
T279 31064-31583 Sentence denotes ARDS = acute respiratory distress syndrome; CI, confidence interval; COVID-19, coronavirus disease 2019; CT, computed tomography; EOT, end of treatment; HR, hazard ratio; Ig, immunoglobulin; IL-1, interleukin 1; IQR, interquartile range; ITT, intent to treat; mITT, modified intent to treat; Pao2/Fio2, of arterial oxygen partial pressure to fractional inspired oxygen; RCT, randomized controlled trial; RT-PCR, real-time PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; WHO, World Health Organization.

2_test

Id Subject Object Predicate Lexical cue
32360444-32187464-22369752 12051-12053 32187464 denotes 22