PMC:7195088 / 22875-25323
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
680 | 142-150 | Species | denotes | patients | Tax:9606 |
681 | 193-201 | Species | denotes | patients | Tax:9606 |
682 | 275-283 | Species | denotes | patients | Tax:9606 |
813 | 0-11 | Chemical | denotes | Favipiravir | MESH:C462182 |
814 | 164-175 | Chemical | denotes | favipiravir | MESH:C462182 |
815 | 212-222 | Chemical | denotes | umifenovir | MESH:C086979 |
816 | 294-305 | Chemical | denotes | favipiravir | MESH:C462182 |
947 | 133-141 | Disease | denotes | COVID-19 | MESH:C000657245 |
948 | 184-192 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T20 | 27-30 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T21 | 41-44 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T22 | 1652-1658 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T19 | 1652-1658 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T111 | 17-26 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T112 | 133-141 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T113 | 184-192 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T114 | 473-481 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T115 | 687-695 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T116 | 974-982 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T117 | 1052-1060 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T118 | 1201-1209 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T119 | 1461-1469 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T120 | 1753-1761 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T121 | 2034-2042 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T122 | 2321-2329 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T123 | 2399-2407 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T112 | 71-72 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T113 | 97-98 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T114 | 360-364 | http://purl.obolibrary.org/obo/CLO_0008416 | denotes | peer |
T115 | 360-364 | http://purl.obolibrary.org/obo/CLO_0050081 | denotes | peer |
T116 | 488-493 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
T117 | 989-994 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
T118 | 1216-1221 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
T119 | 1318-1319 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T120 | 1535-1536 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T121 | 1627-1628 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T122 | 1768-1773 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
T123 | 1850-1854 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T124 | 2336-2341 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | label |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T270 | 41-65 | Chemical | denotes | RNA polymerase inhibitor | http://purl.obolibrary.org/obo/CHEBI_37416 |
T271 | 56-65 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T272 | 164-175 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T273 | 212-222 | Chemical | denotes | umifenovir | http://purl.obolibrary.org/obo/CHEBI_134730 |
T274 | 294-305 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T275 | 395-406 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T276 | 411-422 | Chemical | denotes | tocilizumab | http://purl.obolibrary.org/obo/CHEBI_64360 |
T277 | 427-438 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T278 | 444-455 | Chemical | denotes | tocilizumab | http://purl.obolibrary.org/obo/CHEBI_64360 |
T279 | 488-493 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
T280 | 595-606 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T281 | 612-623 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T282 | 628-639 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T283 | 645-664 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T284 | 645-654 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T285 | 655-664 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T286 | 703-722 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T287 | 703-712 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T288 | 713-722 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T289 | 728-739 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T290 | 744-753 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T291 | 754-763 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T292 | 769-780 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T293 | 785-796 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T294 | 802-821 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T295 | 802-811 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T296 | 812-821 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T297 | 826-835 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T298 | 836-845 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T299 | 851-862 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T300 | 868-879 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T301 | 884-893 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T302 | 894-903 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T303 | 909-920 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T304 | 926-937 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T305 | 989-994 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
T306 | 1118-1136 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T307 | 1142-1151 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T308 | 1152-1162 | Chemical | denotes | cobicistat | http://purl.obolibrary.org/obo/CHEBI_72291 |
T309 | 1216-1221 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
T310 | 1387-1398 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T311 | 1404-1415 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T312 | 1420-1431 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T313 | 1703-1714 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T314 | 1768-1773 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
T315 | 1837-1849 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
T316 | 1845-1849 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T317 | 1942-1953 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T318 | 1959-1970 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T319 | 1975-1986 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T320 | 1992-2011 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T321 | 1992-2001 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T322 | 2002-2011 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T323 | 2050-2069 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T324 | 2050-2059 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T325 | 2060-2069 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T326 | 2075-2086 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T327 | 2091-2100 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T328 | 2101-2110 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T329 | 2116-2127 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T330 | 2132-2143 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T331 | 2149-2168 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
T332 | 2149-2158 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T333 | 2159-2168 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T334 | 2173-2182 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T335 | 2183-2192 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T336 | 2198-2209 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T337 | 2215-2226 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T338 | 2231-2240 | Chemical | denotes | darunavir | http://purl.obolibrary.org/obo/CHEBI_367163 |
T339 | 2241-2250 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
T340 | 2256-2267 | Chemical | denotes | favipiravir | http://purl.obolibrary.org/obo/CHEBI_134722 |
T341 | 2273-2284 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T342 | 2336-2341 | Chemical | denotes | label | http://purl.obolibrary.org/obo/CHEBI_35209 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T170 | 0-306 | Sentence | denotes | Favipiravir Anti-influenza RNA-dependent RNA polymerase inhibitor • In a recent RCT published on a preprint server and comparing 120 COVID-19 patients treated with favipiravir vs. 120 COVID-19 patients receiving umifenovir, higher rates of clinical recovery were observed in patients receiving favipiravir. |
T171 | 307-482 | Sentence | denotes | The manuscript is publicly available but still to be peer reviewed [30] • Comparison of favipiravir vs. tocilizumab vs. favipiravir plus tocilizumab in patients with COVID-19. |
T172 | 483-524 | Sentence | denotes | Open-label RCT (NCT04310228, recruiting). |
T173 | 525-578 | Sentence | denotes | Primary endpoint: clinical cure (follow-up 3 months). |
T174 | 579-983 | Sentence | denotes | • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19. |
T175 | 984-1033 | Sentence | denotes | Open-label RCT (NCT04303299, not yet recruiting). |
T176 | 1034-1101 | Sentence | denotes | Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks). |
T177 | 1102-1210 | Sentence | denotes | • Comparison of hydroxychloroquine plus darunavir/cobicistat vs. standard of care in patients with COVID-19. |
T178 | 1211-1252 | Sentence | denotes | Open-label RCT (NCT04304053, recruiting). |
T179 | 1253-1370 | Sentence | denotes | Primary endpoint: incidence of secondary cases among contacts of a case and contacts of contacts (follow-up 14 days). |
T180 | 1371-1470 | Sentence | denotes | • Comparison of chloroquine plus favipiravir vs. favipiravir vs. placebo in patients with COVID-19. |
T181 | 1471-1514 | Sentence | denotes | Double-blind RCT (NCT04319900, recruiting). |
T182 | 1515-1686 | Sentence | denotes | Primary endpoints: (a) time to improvement/recovery and frequency of improvement/recovery (follow-up 10 days); (b) time to negative swab/sputum RT-PCR (follow-up 10 days). |
T183 | 1687-1762 | Sentence | denotes | • Comparison of favipiravir vs. standard of care in patients with COVID-19. |
T184 | 1763-1812 | Sentence | denotes | Open-label RCT (NCT04333589, not yet recruiting). |
T185 | 1813-1925 | Sentence | denotes | Primary endpoint: viral nucleic acid test negative conversion rate in nasopharyngeal swabs (follow-up 5 months). |
T186 | 1926-2330 | Sentence | denotes | • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19. |
T187 | 2331-2380 | Sentence | denotes | Open-label RCT (NCT04303299, not yet recruiting). |
T188 | 2381-2448 | Sentence | denotes | Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks). |