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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 71-79 Disease denotes COVID-19 MESH:C000657245
7 229-276 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
8 278-288 Species denotes SARS-CoV-2 Tax:2697049
9 316-340 Disease denotes coronavirus disease 2019 MESH:C000657245
10 342-350 Disease denotes COVID-19 MESH:C000657245
11 514-533 Disease denotes respiratory failure MESH:D012131
13 815-823 Disease denotes COVID-19 MESH:C000657245
19 1327-1335 Species denotes patients Tax:9606
20 1508-1516 Species denotes patients Tax:9606
21 1800-1808 Species denotes patients Tax:9606
22 1341-1349 Disease denotes COVID-19 MESH:C000657245
23 1791-1799 Disease denotes COVID-19 MESH:C000657245
30 1824-1871 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
31 1873-1883 Species denotes SARS-CoV-2 Tax:2697049
32 2446-2454 Species denotes patients Tax:9606
33 1911-1935 Disease denotes coronavirus disease 2019 MESH:C000657245
34 1937-1945 Disease denotes COVID-19 MESH:C000657245
35 2125-2144 Disease denotes respiratory failure MESH:D012131
39 2852-2860 Species denotes patients Tax:9606
40 2883-2889 Chemical denotes oxygen MESH:D010100
41 3087-3095 Disease denotes COVID-19 MESH:C000657245
44 3465-3473 Species denotes patients Tax:9606
45 3456-3464 Disease denotes COVID-19 MESH:C000657245
152 4945-4953 Species denotes patients Tax:9606
153 5253-5260 Species denotes patient Tax:9606
154 5521-5529 Species denotes patients Tax:9606
155 5891-5899 Species denotes patients Tax:9606
156 6141-6149 Species denotes patients Tax:9606
157 6724-6732 Species denotes patients Tax:9606
158 6926-6936 Species denotes SARS-CoV-2 Tax:2697049
159 7652-7660 Species denotes patients Tax:9606
160 7875-7883 Species denotes patients Tax:9606
161 8044-8052 Species denotes patients Tax:9606
162 8368-8376 Species denotes patients Tax:9606
163 8526-8534 Species denotes patients Tax:9606
164 9027-9035 Species denotes patients Tax:9606
165 9181-9189 Species denotes patients Tax:9606
166 9195-9205 Species denotes SARS-Cov-2 Tax:2697049
167 9386-9394 Species denotes patients Tax:9606
168 9502-9510 Species denotes patients Tax:9606
169 9877-9885 Species denotes patients Tax:9606
170 10056-10064 Species denotes patients Tax:9606
171 10243-10251 Species denotes patients Tax:9606
172 10592-10600 Species denotes patients Tax:9606
173 11271-11279 Species denotes patients Tax:9606
174 11653-11660 Species denotes patient Tax:9606
175 11907-11915 Species denotes patients Tax:9606
176 12041-12049 Species denotes patients Tax:9606
177 12160-12168 Species denotes patients Tax:9606
178 12170-12178 Species denotes patients Tax:9606
179 12327-12335 Species denotes patients Tax:9606
180 12509-12517 Species denotes patients Tax:9606
181 12738-12746 Species denotes patients Tax:9606
182 13064-13072 Species denotes patients Tax:9606
183 13631-13638 Species denotes patient Tax:9606
184 6551-6560 Species denotes influenza Tax:11520
185 12077-12086 Species denotes influenza Tax:11520
186 4817-4823 Chemical denotes oxygen MESH:D010100
187 4912-4918 Chemical denotes oxygen MESH:D010100
188 5239-5244 Chemical denotes water MESH:D014867
189 5295-5301 Chemical denotes oxygen MESH:D010100
190 5871-5878 Chemical denotes LPV/RTV MESH:C558899
191 5979-5988 Chemical denotes darunavir MESH:D000069454
192 6089-6099 Chemical denotes remdesivir MESH:C000606551
193 6309-6320 Chemical denotes favipiravir MESH:C462182
194 6325-6335 Chemical denotes umifenovir MESH:C086979
195 6454-6465 Chemical denotes Oseltamivir MESH:D053139
196 6469-6478 Chemical denotes zanamivir MESH:D053243
197 6581-6611 Chemical denotes chloroquine/hydroxychloroquine
198 6664-6682 Chemical denotes hydroxychloroquine MESH:D006886
199 7281-7299 Chemical denotes hydroxychloroquine MESH:D006886
200 7579-7597 Chemical denotes hydroxychloroquine MESH:D006886
201 8883-8891 Chemical denotes steroids MESH:D013256
202 9746-9753 Chemical denotes steroid MESH:D013256
203 9823-9830 Chemical denotes steroid MESH:D013256
204 10041-10052 Chemical denotes tocilizumab MESH:C502936
205 10523-10534 Chemical denotes tocilizumab MESH:C502936
206 11579-11585 Chemical denotes oxygen MESH:D010100
207 12015-12026 Chemical denotes oseltamivir MESH:D053139
208 12445-12463 Chemical denotes hydroxychloroquine MESH:D006886
209 12680-12698 Chemical denotes hydroxychloroquine MESH:D006886
210 12800-12830 Chemical denotes Chloroquine/hydroxychloroquine
211 13253-13263 Chemical denotes remdesivir MESH:C000606551
212 13715-13722 Chemical denotes steroid MESH:D013256
213 4959-4986 Disease denotes hypoxic respiratory failure MESH:D012131
214 5535-5543 Disease denotes COVID-19 MESH:C000657245
215 5882-5890 Disease denotes COVID-19 MESH:C000657245
216 6132-6140 Disease denotes COVID-19 MESH:C000657245
217 6738-6746 Disease denotes COVID-19 MESH:C000657245
218 6862-6877 Disease denotes QT prolongation MESH:D008133
219 7251-7260 Disease denotes mortality MESH:D003643
220 7860-7874 Disease denotes critically ill MESH:D016638
221 7889-7898 Disease denotes pneumonia MESH:D011014
222 7906-7914 Disease denotes COVID-19 MESH:C000657245
223 7923-7942 Disease denotes bacterial infection MESH:D001424
224 8015-8026 Disease denotes coinfection MESH:D060085
225 8058-8073 Disease denotes viral pneumonia
226 8190-8199 Disease denotes mortality MESH:D003643
227 8359-8367 Disease denotes COVID-19 MESH:C000657245
228 8517-8525 Disease denotes COVID-19 MESH:C000657245
229 8597-8606 Disease denotes pneumonia MESH:D011014
230 8626-8635 Disease denotes pneumonia MESH:D011014
231 9041-9061 Disease denotes SARS-CoV-2 infection MESH:C000657245
232 9246-9258 Disease denotes inflammation MESH:D007249
233 9280-9291 Disease denotes lung injury MESH:D055370
234 9337-9346 Disease denotes pneumonia MESH:D011014
235 9377-9385 Disease denotes COVID-19 MESH:C000657245
236 9478-9492 Disease denotes critically ill MESH:D016638
237 9493-9501 Disease denotes COVID-19 MESH:C000657245
238 9516-9520 Disease denotes ARDS MESH:D012128
239 9546-9570 Disease denotes ARDS respiratory failure MESH:D012131
240 9849-9867 Disease denotes non–critically ill MESH:D016638
241 9868-9876 Disease denotes COVID-19 MESH:C000657245
242 10070-10078 Disease denotes COVID-19 MESH:C000657245
243 10234-10242 Disease denotes COVID-19 MESH:C000657245
244 10450-10460 Disease denotes infections MESH:D007239
245 10564-10572 Disease denotes COVID-19 MESH:C000657245
246 11416-11424 Disease denotes COVID-19 MESH:C000657245
247 11722-11730 Disease denotes asthenia MESH:D001247
248 11737-11742 Disease denotes fever MESH:D005334
249 11755-11760 Disease denotes cough MESH:D003371
250 11921-11941 Disease denotes SARS-CoV-2 infection MESH:C000657245
251 12184-12188 Disease denotes ARDS MESH:D012128
252 12214-12238 Disease denotes ARDS respiratory failure MESH:D012131
253 12318-12326 Disease denotes COVID-19 MESH:C000657245
254 12500-12508 Disease denotes COVID-19 MESH:C000657245
255 12668-12676 Disease denotes toxicity MESH:D064420
256 13055-13063 Disease denotes COVID-19 MESH:C000657245
257 13184-13225 Disease denotes QT prolongation or hepatic/renal toxicity MESH:D056486
265 14178-14188 Species denotes SARS-CoV-2 Tax:2697049
266 14190-14237 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
267 14074-14081 Chemical denotes LPV/RTV MESH:C558899
268 14083-14102 Chemical denotes lopinavir/ritonavir MESH:C558899
269 13895-13899 Disease denotes ARDS MESH:D012128
270 13901-13936 Disease denotes acute respiratory distress syndrome MESH:D012128
271 13948-13972 Disease denotes coronavirus disease 2019 MESH:C000657245
643 14681-14687 Gene denotes CYP3A4 Gene:1576
644 22553-22559 Gene denotes CYP3A4 Gene:1576
653 14786-14794 Species denotes patients Tax:9606
654 14826-14834 Species denotes patients Tax:9606
655 15704-15712 Species denotes patients Tax:9606
656 15894-15902 Species denotes patients Tax:9606
657 16238-16246 Species denotes patients Tax:9606
658 16483-16491 Species denotes patients Tax:9606
659 16732-16740 Species denotes patients Tax:9606
660 17437-17445 Species denotes patients Tax:9606
661 17863-17871 Species denotes patients Tax:9606
662 18145-18153 Species denotes patients Tax:9606
663 18437-18445 Species denotes patients Tax:9606
664 18753-18761 Species denotes patients Tax:9606
665 19021-19029 Species denotes patients Tax:9606
666 19330-19338 Species denotes patients Tax:9606
667 19756-19764 Species denotes patients Tax:9606
668 20121-20129 Species denotes patients Tax:9606
669 20362-20370 Species denotes patients Tax:9606
670 20635-20643 Species denotes patients Tax:9606
671 20746-20756 Species denotes SARS-CoV-2 Tax:2697049
672 20962-20970 Species denotes patients Tax:9606
673 21169-21177 Species denotes patients Tax:9606
674 21385-21393 Species denotes patients Tax:9606
675 21623-21631 Species denotes patients Tax:9606
676 21787-21795 Species denotes patients Tax:9606
677 22019-22027 Species denotes patients Tax:9606
678 22319-22327 Species denotes patients Tax:9606
679 22684-22692 Species denotes patients Tax:9606
680 23017-23025 Species denotes patients Tax:9606
681 23068-23076 Species denotes patients Tax:9606
682 23150-23158 Species denotes patients Tax:9606
683 64308-64316 Species denotes patients Tax:9606
728 14599-14618 Chemical denotes Lopinavir/ritonavir MESH:C558899
729 14619-14628 Chemical denotes Lopinavir MESH:D061466
730 14666-14675 Chemical denotes Ritonavir MESH:D019438
731 14710-14719 Chemical denotes lopinavir MESH:D061466
732 14762-14781 Chemical denotes lopinavir/ritonavir MESH:C558899
733 14859-14878 Chemical denotes Lopinavir/ritonavir MESH:C558899
734 15430-15449 Chemical denotes lopinavir/ritonavir MESH:C558899
735 15658-15677 Chemical denotes lopinavir/ritonavir MESH:C558899
736 15682-15700 Chemical denotes hydroxychloroquine MESH:D006886
737 15851-15856 Chemical denotes ASC09
738 15857-15866 Chemical denotes ritonavir MESH:D019438
739 15871-15890 Chemical denotes lopinavir/ritonavir MESH:C558899
740 16067-16073 Chemical denotes oxygen MESH:D010100
741 16096-16100 Chemical denotes FiO2
742 16175-16194 Chemical denotes lopinavir/ritonavir MESH:C558899
743 16199-16218 Chemical denotes lopinavir/ritonavir MESH:C558899
744 16224-16234 Chemical denotes umifenovir MESH:C086979
745 16397-16416 Chemical denotes lopinavir/ritonavir MESH:C558899
746 16421-16440 Chemical denotes lopinavir/ritonavir MESH:C558899
747 16446-16455 Chemical denotes ribavirin MESH:D012254
748 16678-16697 Chemical denotes lopinavir/ritonavir MESH:C558899
749 16702-16713 Chemical denotes oseltamivir MESH:D053139
750 16718-16728 Chemical denotes umifenovir MESH:C086979
751 17132-17151 Chemical denotes lopinavir/ritonavir MESH:C558899
752 17370-17380 Chemical denotes carrimycin
753 17385-17404 Chemical denotes lopinavir/ritonavir MESH:C558899
754 17408-17418 Chemical denotes umifenovir MESH:C086979
755 17422-17433 Chemical denotes chloroquine MESH:D002738
756 17720-17739 Chemical denotes lopinavir/ritonavir MESH:C558899
757 17744-17763 Chemical denotes lopinavir/ritonavir MESH:C558899
758 18015-18034 Chemical denotes lopinavir/ritonavir MESH:C558899
759 18068-18087 Chemical denotes lopinavir/ritonavir MESH:C558899
760 18122-18131 Chemical denotes xiyanping
761 18297-18316 Chemical denotes lopinavir/ritonavir MESH:C558899
762 18350-18369 Chemical denotes lopinavir/ritonavir MESH:C558899
763 18597-18616 Chemical denotes lopinavir/ritonavir MESH:C558899
764 18622-18640 Chemical denotes hydroxychloroquine MESH:D006886
765 18645-18664 Chemical denotes lopinavir/ritonavir MESH:C558899
766 18670-18688 Chemical denotes hydroxychloroquine MESH:D006886
767 18694-18704 Chemical denotes levamisole MESH:D007978
768 18715-18725 Chemical denotes budesonide MESH:D019819
769 18731-18741 Chemical denotes formoterol MESH:D000068759
770 18949-18968 Chemical denotes lopinavir/ritonavir MESH:C558899
771 18973-18991 Chemical denotes hydroxychloroquine MESH:D006886
772 18996-19004 Chemical denotes losartan MESH:D019808
773 19200-19219 Chemical denotes lopinavir/ritonavir MESH:C558899
774 19224-19242 Chemical denotes hydroxychloroquine MESH:D006886
775 19247-19266 Chemical denotes lopinavir/ritonavir MESH:C558899
776 19295-19305 Chemical denotes remdesivir MESH:C000606551
777 19496-19515 Chemical denotes lopinavir/ritonavir MESH:C558899
778 19519-19529 Chemical denotes umifenovir MESH:C086979
779 19533-19544 Chemical denotes chloroquine MESH:D002738
780 19548-19566 Chemical denotes hydroxychloroquine MESH:D006886
781 19570-19581 Chemical denotes oseltamivir MESH:D053139
782 19599-19611 Chemical denotes azithromycin MESH:D017963
783 19636-19655 Chemical denotes lopinavir/ritonavir MESH:C558899
784 19659-19669 Chemical denotes umifenovir MESH:C086979
785 19673-19684 Chemical denotes chloroquine MESH:D002738
786 19688-19706 Chemical denotes hydroxychloroquine MESH:D006886
787 19710-19721 Chemical denotes oseltamivir MESH:D053139
788 19739-19751 Chemical denotes azithromycin MESH:D017963
789 20042-20052 Chemical denotes colchicine MESH:D003078
790 20070-20089 Chemical denotes lopinavir/ritonavir MESH:C558899
791 20339-20358 Chemical denotes lopinavir/ritonavir MESH:C558899
792 20397-20416 Chemical denotes lopinavir/ritonavir MESH:C558899
793 20496-20515 Chemical denotes lopinavir/ritonavir MESH:C558899
794 20796-20806 Chemical denotes Remdesivir MESH:C000606551
795 20807-20816 Chemical denotes Adenosine MESH:D000241
796 20936-20946 Chemical denotes remdesivir MESH:C000606551
797 21143-21153 Chemical denotes remdesivir MESH:C000606551
798 21344-21354 Chemical denotes remdesivir MESH:C000606551
799 21513-21519 Chemical denotes oxygen MESH:D010100
800 21582-21592 Chemical denotes remdesivir MESH:C000606551
801 21761-21771 Chemical denotes remdesivir MESH:C000606551
802 21943-21953 Chemical denotes remdesivir MESH:C000606551
803 21958-21976 Chemical denotes hydroxychloroquine MESH:D006886
804 21981-21991 Chemical denotes remdesivir MESH:C000606551
805 21997-22015 Chemical denotes hydroxychloroquine MESH:D006886
806 22189-22208 Chemical denotes lopinavir/ritonavir MESH:C558899
807 22213-22231 Chemical denotes hydroxychloroquine MESH:D006886
808 22236-22255 Chemical denotes lopinavir/ritonavir MESH:C558899
809 22284-22294 Chemical denotes remdesivir MESH:C000606551
810 22469-22478 Chemical denotes Darunavir MESH:D000069454
811 22479-22499 Chemical denotes cobicistat Darunavir
812 22582-22591 Chemical denotes darunavir MESH:D000069454
813 22875-22886 Chemical denotes Favipiravir MESH:C462182
814 23039-23050 Chemical denotes favipiravir MESH:C462182
815 23087-23097 Chemical denotes umifenovir MESH:C086979
816 23169-23180 Chemical denotes favipiravir MESH:C462182
822 69391-69409 Chemical denotes hydroxychloroquine MESH:D006886
905 14522-14530 Disease denotes COVID-19 MESH:C000657245
906 14840-14848 Disease denotes COVID-19 MESH:C000657245
907 15274-15283 Disease denotes mortality MESH:D003643
908 15723-15731 Disease denotes COVID-19 MESH:C000657245
909 15918-15926 Disease denotes COVID-19 MESH:C000657245
910 16252-16260 Disease denotes COVID-19 MESH:C000657245
911 16497-16505 Disease denotes COVID-19 MESH:C000657245
912 16756-16774 Disease denotes COVID-19 pneumonia MESH:C000657245
913 16882-16887 Disease denotes fever MESH:D005334
914 16889-16894 Disease denotes cough MESH:D003371
915 16962-16967 Disease denotes fever MESH:D005334
916 16969-16974 Disease denotes cough MESH:D003371
917 17197-17205 Disease denotes COVID-19 MESH:C000657245
918 17321-17329 Disease denotes COVID-19 MESH:C000657245
919 17451-17469 Disease denotes COVID-19 pneumonia MESH:C000657245
920 17544-17549 Disease denotes fever MESH:D005334
921 17590-17612 Disease denotes pulmonary inflammation MESH:D011014
922 17877-17885 Disease denotes COVID-19 MESH:C000657245
923 18159-18167 Disease denotes COVID-19 MESH:C000657245
924 18451-18459 Disease denotes COVID-19 MESH:C000657245
925 18777-18795 Disease denotes COVID-19 pneumonia MESH:C000657245
926 19035-19043 Disease denotes COVID-19 MESH:C000657245
927 19131-19139 Disease denotes COVID-19 MESH:C000657245
928 19344-19352 Disease denotes COVID-19 MESH:C000657245
929 19770-19778 Disease denotes COVID-19 MESH:C000657245
930 19897-19902 Disease denotes fever MESH:D005334
931 19972-19989 Disease denotes lung inflammation MESH:D011014
932 20154-20162 Disease denotes COVID-19 MESH:C000657245
933 20242-20251 Disease denotes mortality MESH:D003643
934 20381-20389 Disease denotes COVID-19 MESH:C000657245
935 20588-20619 Disease denotes ritonavir plus favipiravir plus MESH:D007625
936 20668-20676 Disease denotes COVID-19 MESH:C000657245
937 20983-20991 Disease denotes COVID-19 MESH:C000657245
938 21200-21208 Disease denotes COVID-19 MESH:C000657245
939 21406-21414 Disease denotes COVID-19 MESH:C000657245
940 21489-21494 Disease denotes fever MESH:D005334
941 21646-21654 Disease denotes COVID-19 MESH:C000657245
942 21801-21809 Disease denotes COVID-19 MESH:C000657245
943 22033-22041 Disease denotes COVID-19 MESH:C000657245
944 22142-22151 Disease denotes mortality MESH:D003643
945 22333-22341 Disease denotes COVID-19 MESH:C000657245
946 22698-22716 Disease denotes COVID-19 pneumonia MESH:C000657245
947 23008-23016 Disease denotes COVID-19 MESH:C000657245
948 23059-23067 Disease denotes COVID-19 MESH:C000657245
950 64322-64330 Disease denotes COVID-19 MESH:C000657245
1015 14429-14437 Disease denotes COVID-19 MESH:C000657245
1022 34544-34552 Species denotes patients Tax:9606
1023 34608-34619 Chemical denotes ruxolitinib MESH:C540383
1024 34621-34632 Chemical denotes baricitinib MESH:C000596027
1025 34637-34648 Chemical denotes tofacitinib MESH:C479163
1026 34404-34412 Disease denotes COVID-19 MESH:C000657245
1027 34558-34566 Disease denotes COVID-19 MESH:C000657245
1035 34842-34846 Gene denotes IL-1 Gene:3552
1036 34848-34861 Gene denotes interleukin 1 Gene:3552
1037 35078-35088 Species denotes SARS-CoV-2 Tax:2697049
1038 35090-35137 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
1039 34651-34655 Disease denotes ARDS MESH:D012128
1040 34658-34693 Disease denotes acute respiratory distress syndrome MESH:D012128
1041 34730-34754 Disease denotes coronavirus disease 2019 MESH:C000657245
1047 4482-4490 Species denotes patients Tax:9606
1048 3855-3874 Disease denotes infectious diseases MESH:D003141
1049 4473-4481 Disease denotes COVID-19 MESH:C000657245
1050 4622-4630 Disease denotes COVID-19 MESH:C000657245
1051 4639-4675 Disease denotes cardiovascular/coagulative disorders MESH:D002318
1053 35203-35209 Chemical denotes oxygen MESH:D010100
1064 35537-35545 Species denotes patients Tax:9606
1065 35654-35662 Species denotes patients Tax:9606
1066 35472-35478 Chemical denotes oxygen MESH:D010100
1067 35313-35321 Disease denotes COVID-19 MESH:C000657245
1068 35344-35356 Disease denotes lung disease MESH:D008171
1069 35403-35412 Disease denotes pneumonia MESH:D011014
1070 35422-35449 Disease denotes hypoxic respiratory failure MESH:D012131
1071 35506-35533 Disease denotes hypoxic respiratory failure MESH:D012131
1072 35551-35559 Disease denotes COVID-19 MESH:C000657245
1073 35645-35653 Disease denotes COVID-19 MESH:C000657245
1080 35841-35849 Species denotes patients Tax:9606
1081 36071-36076 Species denotes women Tax:9606
1082 35802-35808 Chemical denotes oxygen MESH:D010100
1083 35984-35990 Chemical denotes oxygen MESH:D010100
1084 36086-36092 Chemical denotes oxygen MESH:D010100
1085 35855-35888 Disease denotes shortness of breath or hypoxaemia MESH:D004417
1113 36780-36788 Species denotes patients Tax:9606
1114 37549-37556 Species denotes patient Tax:9606
1115 38231-38239 Species denotes patients Tax:9606
1116 38415-38423 Species denotes patients Tax:9606
1117 38791-38799 Species denotes patients Tax:9606
1118 36176-36182 Chemical denotes oxygen MESH:D010100
1119 36269-36275 Chemical denotes oxygen MESH:D010100
1120 36325-36331 Chemical denotes oxygen MESH:D010100
1121 36408-36414 Chemical denotes oxygen MESH:D010100
1122 36509-36523 Chemical denotes carbon dioxide MESH:D002245
1123 36599-36605 Chemical denotes oxygen MESH:D010100
1124 36865-36871 Chemical denotes oxygen MESH:D010100
1125 37594-37600 Chemical denotes oxygen MESH:D010100
1126 37648-37654 Chemical denotes oxygen MESH:D010100
1127 37695-37701 Chemical denotes oxygen MESH:D010100
1128 38541-38546 Chemical denotes water MESH:D014867
1129 36794-36802 Disease denotes COVID-19 MESH:C000657245
1130 37184-37193 Disease denotes infection MESH:D007239
1131 37918-37937 Disease denotes respiratory failure MESH:D012131
1132 38086-38098 Disease denotes lung failure MESH:D012131
1133 38162-38170 Disease denotes COVID-19 MESH:C000657245
1134 38207-38221 Disease denotes critically ill MESH:D016638
1135 38222-38230 Disease denotes COVID-19 MESH:C000657245
1136 38400-38411 Disease denotes lung injury MESH:D055370
1137 38429-38437 Disease denotes COVID-19 MESH:C000657245
1138 38805-38813 Disease denotes COVID-19 MESH:C000657245
1139 39040-39070 Disease denotes decreased respiratory distress MESH:D012128
1148 39185-39193 Species denotes patients Tax:9606
1149 39495-39502 Species denotes patient Tax:9606
1150 39763-39771 Species denotes patients Tax:9606
1151 39152-39158 Chemical denotes oxygen MESH:D010100
1152 39481-39486 Chemical denotes water MESH:D014867
1153 39537-39543 Chemical denotes oxygen MESH:D010100
1154 39199-39226 Disease denotes hypoxic respiratory failure MESH:D012131
1155 39777-39785 Disease denotes COVID-19 MESH:C000657245
1203 43597-43600 Gene denotes AST Gene:26503
1204 43182-43190 Species denotes patients Tax:9606
1205 43720-43728 Species denotes patients Tax:9606
1206 43903-43929 Species denotes Mycobacterium tuberculosis Tax:1773
1207 44129-44137 Species denotes patients Tax:9606
1208 42699-42712 Chemical denotes triglycerides MESH:D014280
1209 43976-43987 Chemical denotes tocilizumab MESH:C502936
1210 42645-42678 Disease denotes ritonavir • Hypercholesterolaemia MESH:C564286
1211 42767-42776 Disease denotes Diarrhoea MESH:D003967
1212 42860-42866 Disease denotes Nausea MESH:D009325
1213 42877-42910 Disease denotes Upper respiratory tract infection MESH:D012141
1214 42919-42933 Disease denotes Abdominal pain MESH:D015746
1215 42962-42969 Disease denotes Fatigue MESH:D005221
1216 43024-43032 Disease denotes Headache MESH:D006261
1217 43042-43051 Disease denotes Skin rash MESH:D005076
1218 43060-43071 Disease denotes Neutropenia MESH:D009503
1219 43092-43099 Disease denotes Anxiety MESH:D001007
1220 43107-43115 Disease denotes Insomnia MESH:D007319
1221 43155-43166 Disease denotes Retinopathy MESH:D012164
1222 43249-43273 Disease denotes Stevens-Johnson syndrome MESH:D013262
1223 43275-43289 Disease denotes abdominal pain MESH:D015746
1224 43291-43300 Disease denotes diarrhoea MESH:D003967
1225 43302-43308 Disease denotes nausea MESH:D009325
1226 43310-43318 Disease denotes vomiting MESH:D014839
1227 43320-43335 Disease denotes agranulocytosis MESH:D000380
1228 43337-43347 Disease denotes leukopenia MESH:D007970
1229 43349-43365 Disease denotes thrombocytopenia MESH:D013921
1230 43422-43430 Disease denotes myopathy MESH:D009135
1231 43432-43444 Disease denotes bronchospasm MESH:D001986
1232 43680-43691 Disease denotes Neutropenia MESH:D009503
1233 43732-43740 Disease denotes Headache MESH:D006261
1234 43750-43762 Disease denotes Hypertension MESH:D006973
1235 43772-43781 Disease denotes Dizziness MESH:D004244
1236 43789-43803 Disease denotes Hypothyroidism MESH:D007037
1237 43812-43826 Disease denotes Abdominal pain MESH:D015746
1238 43849-43863 Disease denotes gastric ulcers MESH:D013276
1239 43871-43881 Disease denotes Infections MESH:D007239
1240 43889-43901 Disease denotes Pneumocystis MESH:D011020
1241 44204-44212 Disease denotes Headache MESH:D006261
1242 44217-44225 Disease denotes vomiting MESH:D014839
1243 44237-44247 Disease denotes Arthralgia MESH:D018771
1244 44259-44264 Disease denotes Fever MESH:D005334
1245 44276-44297 Disease denotes Haematologic disorder MESH:D006402
1246 44308-44320 Disease denotes eosinophilia MESH:D004802
1247 44322-44332 Disease denotes leukopenia MESH:D007970
1248 44371-44377 Disease denotes Nausea MESH:D009325
1249 44382-44391 Disease denotes diarrhoea MESH:D003967
1251 42597-42605 Disease denotes COVID-19 MESH:C000657245
1253 44498-44506 Disease denotes COVID-19 MESH:C000657245
1257 44566-44590 Gene denotes alanine aminotransferase Gene:2875
1258 44592-44595 Gene denotes AST Gene:26503
1259 44635-44659 Disease denotes coronavirus disease 2019 MESH:C000657245
1264 44911-44921 Disease denotes infections MESH:D007239
1265 44931-44941 Disease denotes cellulitis MESH:D002481
1266 44943-44952 Disease denotes pneumonia MESH:D011014
1267 44958-44983 Disease denotes bone and joint infections MESH:D007239
1294 40101-40111 Species denotes SARS-CoV-2 Tax:2697049
1295 40121-40134 Species denotes coronaviruses Tax:11118
1296 40193-40204 Species denotes coronavirus Tax:11118
1297 40378-40386 Species denotes patients Tax:9606
1298 40500-40508 Species denotes SARS-CoV Tax:694009
1299 40552-40561 Species denotes MERS)-CoV Tax:1335626
1300 40720-40728 Species denotes patients Tax:9606
1301 41027-41035 Species denotes patients Tax:9606
1302 42058-42066 Species denotes patients Tax:9606
1303 42198-42206 Species denotes patients Tax:9606
1304 40314-40323 Chemical denotes Lopinavir MESH:D061466
1305 40421-40430 Chemical denotes ritonavir MESH:D019438
1306 40622-40641 Chemical denotes lopinavir/ritonavir MESH:C558899
1307 40643-40650 Chemical denotes LPV/RTV MESH:C558899
1308 41069-41076 Chemical denotes LPV/RTV MESH:C558899
1309 41451-41458 Chemical denotes LPV/RTV MESH:C558899
1310 41682-41689 Chemical denotes LPV/RTV MESH:C558899
1311 41776-41783 Chemical denotes LPV/RTV MESH:C558899
1312 41986-41993 Chemical denotes LPV/RTV MESH:C558899
1313 42311-42329 Chemical denotes hydroxychloroquine MESH:D006886
1314 40518-40550 Disease denotes Middle East respiratory syndrome MESH:D018352
1315 40711-40719 Disease denotes COVID-19 MESH:C000657245
1316 41006-41011 Disease denotes death MESH:D003643
1317 41381-41390 Disease denotes mortality MESH:D003643
1318 41421-41427 Disease denotes deaths MESH:D003643
1319 42049-42057 Disease denotes COVID-19 MESH:C000657245
1329 45074-45079 Species denotes Ebola Tax:1570291
1330 45118-45131 Species denotes coronaviruses Tax:11118
1331 45133-45143 Species denotes SARS-CoV-2 Tax:2697049
1332 45145-45153 Species denotes SARS-CoV Tax:694009
1333 45160-45168 Species denotes MERS-CoV Tax:1335626
1334 45305-45313 Species denotes patients Tax:9606
1335 44985-44995 Chemical denotes Remdesivir MESH:C000606551
1336 45443-45453 Chemical denotes remdesivir MESH:C000606551
1337 45296-45304 Disease denotes COVID-19 MESH:C000657245
1357 45607-45620 Gene denotes neuraminidase Gene:4758
1358 45717-45725 Species denotes patients Tax:9606
1359 45833-45841 Species denotes SARS-CoV Tax:694009
1360 45915-45923 Species denotes patients Tax:9606
1361 46150-46158 Species denotes patients Tax:9606
1362 45650-45659 Species denotes influenza Tax:11520
1363 46031-46040 Species denotes influenza Tax:11520
1364 46214-46223 Species denotes influenza Tax:11520
1365 45577-45588 Chemical denotes Oseltamivir MESH:D053139
1366 45593-45602 Chemical denotes zanamivir MESH:D053243
1367 45770-45781 Chemical denotes oseltamivir MESH:D053139
1368 45786-45795 Chemical denotes zanamivir MESH:D053243
1369 45947-45958 Chemical denotes oseltamivir MESH:D053139
1370 45708-45716 Disease denotes COVID-19 MESH:C000657245
1371 45900-45914 Disease denotes critically ill MESH:D016638
1372 45929-45937 Disease denotes COVID-19 MESH:C000657245
1373 45999-46008 Disease denotes infection MESH:D007239
1374 46013-46024 Disease denotes coinfection MESH:D060085
1375 46141-46149 Disease denotes COVID-19 MESH:C000657245
1395 46314-46322 Species denotes patients Tax:9606
1396 46894-46902 Species denotes patients Tax:9606
1397 46948-46956 Species denotes patients Tax:9606
1398 47030-47038 Species denotes patients Tax:9606
1399 47344-47354 Species denotes SARS-CoV-2 Tax:2697049
1400 46392-46401 Species denotes influenza Tax:11520
1401 46437-46446 Species denotes influenza Tax:11520
1402 47293-47301 Species denotes patients Tax:9606
1403 46416-46426 Chemical denotes umifenovir MESH:C086979
1404 46647-46658 Chemical denotes favipiravir MESH:C462182
1405 46916-46927 Chemical denotes favipiravir MESH:C462182
1406 46967-46977 Chemical denotes umifenovir MESH:C086979
1407 47049-47060 Chemical denotes favipiravir MESH:C462182
1408 46305-46313 Disease denotes COVID-19 MESH:C000657245
1409 46885-46893 Disease denotes COVID-19 MESH:C000657245
1410 46939-46947 Disease denotes COVID-19 MESH:C000657245
1411 47099-47108 Disease denotes mortality MESH:D003643
1412 47269-47283 Disease denotes critically ill MESH:D016638
1413 47284-47292 Disease denotes COVID-19 MESH:C000657245
1426 47592-47600 Species denotes patients Tax:9606
1427 47852-47860 Species denotes patients Tax:9606
1428 48259-48268 Species denotes influenza Tax:11520
1429 47572-47579 Chemical denotes LPV/RTV MESH:C558899
1430 47680-47689 Chemical denotes darunavir MESH:D000069454
1431 47790-47800 Chemical denotes remdesivir MESH:C000606551
1432 48020-48031 Chemical denotes favipiravir MESH:C462182
1433 48036-48046 Chemical denotes umifenovir MESH:C086979
1434 48162-48173 Chemical denotes Oseltamivir MESH:D053139
1435 48177-48186 Chemical denotes zanamivir MESH:D053243
1436 47583-47591 Disease denotes COVID-19 MESH:C000657245
1437 47843-47851 Disease denotes COVID-19 MESH:C000657245
1440 48290-48301 Chemical denotes chloroquine MESH:D002738
1441 48302-48320 Chemical denotes hydroxychloroquine MESH:D006886
1458 48926-48953 Gene denotes tumor necrosis factor alpha Gene:7124
1459 48955-48973 Gene denotes interleukin (IL)-6 Gene:3569
1460 48395-48403 Species denotes patients Tax:9606
1461 48635-48643 Species denotes SARS-CoV Tax:694009
1462 48650-48660 Species denotes SARS-CoV-2 Tax:2697049
1463 48766-48769 Species denotes CoV Tax:11118
1464 49183-49191 Species denotes patients Tax:9606
1465 49563-49573 Species denotes SARS-CoV-2 Tax:2697049
1466 48361-48372 Chemical denotes chloroquine MESH:D002738
1467 48553-48564 Chemical denotes chloroquine MESH:D002738
1468 49025-49036 Chemical denotes chloroquine MESH:D002738
1469 49373-49391 Chemical denotes hydroxychloroquine MESH:D006886
1470 49417-49428 Chemical denotes chloroquine MESH:D002738
1471 48386-48394 Disease denotes COVID-19 MESH:C000657245
1472 49163-49182 Disease denotes SARS-CoV-2–infected MESH:C000657245
1473 49479-49487 Disease denotes toxicity MESH:D064420
1480 49773-49781 Species denotes patients Tax:9606
1481 49736-49747 Chemical denotes chloroquine MESH:D002738
1482 49751-49769 Chemical denotes hydroxychloroquine MESH:D006886
1483 50174-50185 Chemical denotes chloroquine MESH:D002738
1484 50186-50204 Chemical denotes hydroxychloroquine MESH:D006886
1485 49787-49795 Disease denotes COVID-19 MESH:C000657245
1508 50432-50440 Species denotes patients Tax:9606
1509 50558-50566 Species denotes patients Tax:9606
1510 50656-50664 Species denotes patients Tax:9606
1511 50705-50713 Species denotes patients Tax:9606
1512 50774-50782 Species denotes patients Tax:9606
1513 51030-51038 Species denotes patients Tax:9606
1514 51503-51511 Species denotes patients Tax:9606
1515 51637-51645 Species denotes patients Tax:9606
1516 51782-51790 Species denotes patients Tax:9606
1517 50454-50472 Chemical denotes hydroxychloroquine MESH:D006886
1518 50588-50606 Chemical denotes hydroxychloroquine MESH:D006886
1519 50796-50814 Chemical denotes hydroxychloroquine MESH:D006886
1520 50829-50841 Chemical denotes azithromycin MESH:D017963
1521 51003-51021 Chemical denotes hydroxychloroquine MESH:D006886
1522 51294-51312 Chemical denotes hydroxychloroquine MESH:D006886
1523 51522-51540 Chemical denotes hydroxychloroquine MESH:D006886
1524 51546-51558 Chemical denotes azithromycin MESH:D017963
1525 51656-51668 Chemical denotes azithromycin MESH:D017963
1526 51684-51702 Chemical denotes hydroxychloroquine MESH:D006886
1527 50423-50431 Disease denotes COVID-19 MESH:C000657245
1528 50549-50557 Disease denotes COVID-19 MESH:C000657245
1529 51861-51876 Disease denotes QT prolongation MESH:D008133
1539 52032-52040 Species denotes patients Tax:9606
1540 52243-52253 Species denotes SARS-CoV-2 Tax:2697049
1541 52968-52976 Species denotes patients Tax:9606
1542 51972-51990 Chemical denotes hydroxychloroquine MESH:D006886
1543 52597-52615 Chemical denotes hydroxychloroquine MESH:D006886
1544 52895-52913 Chemical denotes hydroxychloroquine MESH:D006886
1545 52046-52054 Disease denotes COVID-19 MESH:C000657245
1546 52179-52194 Disease denotes QT prolongation MESH:D008133
1547 52567-52576 Disease denotes mortality MESH:D003643
1561 53241-53249 Species denotes patients Tax:9606
1562 53475-53483 Species denotes patients Tax:9606
1563 53710-53718 Species denotes patients Tax:9606
1564 53107-53117 Disease denotes infections MESH:D007239
1565 53150-53158 Disease denotes COVID-19 MESH:C000657245
1566 53283-53298 Disease denotes viral pneumonia
1567 53350-53361 Disease denotes coinfection MESH:D060085
1568 53451-53471 Disease denotes bacterial infections MESH:D001424
1569 53489-53497 Disease denotes COVID-19 MESH:C000657245
1570 53564-53574 Disease denotes infections MESH:D007239
1571 53701-53709 Disease denotes COVID-19 MESH:C000657245
1572 53897-53908 Disease denotes coinfection MESH:D060085
1573 53958-53966 Disease denotes COVID-19 MESH:C000657245
1590 54201-54209 Species denotes patients Tax:9606
1591 54282-54290 Species denotes patients Tax:9606
1592 54367-54375 Species denotes patients Tax:9606
1593 54574-54595 Species denotes Staphylococcus aureus Tax:1280
1594 54643-54667 Species denotes Streptococcus pneumoniae Tax:1313
1595 54669-54691 Species denotes Haemophilus influenzae Tax:727
1596 54696-54716 Species denotes group A streptococci Tax:36470
1597 54475-54484 Species denotes influenza Tax:11520
1598 54607-54618 Chemical denotes methicillin MESH:D008712
1599 54121-54130 Disease denotes pneumonia MESH:D011014
1600 54186-54200 Disease denotes critically ill MESH:D016638
1601 54237-54256 Disease denotes bacterial infection MESH:D001424
1602 54322-54341 Disease denotes bacterial pneumonia MESH:D016920
1603 54411-54426 Disease denotes virus infection MESH:D001102
1604 54454-54463 Disease denotes mortality MESH:D003643
1605 54523-54532 Disease denotes pneumonia MESH:D011014
1612 54817-54825 Species denotes patients Tax:9606
1613 54986-54994 Species denotes patients Tax:9606
1614 54887-54899 Chemical denotes azithromycin MESH:D017963
1615 54961-54973 Chemical denotes azithromycin MESH:D017963
1616 54808-54816 Disease denotes COVID-19 MESH:C000657245
1617 54977-54985 Disease denotes COVID-19 MESH:C000657245
1633 55147-55155 Species denotes patients Tax:9606
1634 55313-55321 Species denotes patients Tax:9606
1635 55641-55649 Species denotes patients Tax:9606
1636 55799-55807 Species denotes patients Tax:9606
1637 55132-55146 Disease denotes critically ill MESH:D016638
1638 55161-55170 Disease denotes pneumonia MESH:D011014
1639 55178-55186 Disease denotes COVID-19 MESH:C000657245
1640 55195-55214 Disease denotes bacterial infection MESH:D001424
1641 55288-55299 Disease denotes coinfection MESH:D060085
1642 55327-55342 Disease denotes viral pneumonia
1643 55463-55472 Disease denotes mortality MESH:D003643
1644 55632-55640 Disease denotes COVID-19 MESH:C000657245
1645 55790-55798 Disease denotes COVID-19 MESH:C000657245
1646 55870-55879 Disease denotes pneumonia MESH:D011014
1647 55899-55908 Disease denotes pneumonia MESH:D011014
1649 56157-56165 Chemical denotes steroids MESH:D013256
1655 56254-56262 Species denotes patients Tax:9606
1656 56381-56389 Species denotes SARS-CoV Tax:694009
1657 56396-56404 Species denotes MERS-CoV Tax:1335626
1658 56405-56413 Species denotes patients Tax:9606
1659 56268-56276 Disease denotes COVID-19 MESH:C000657245
1670 56477-56485 Species denotes patients Tax:9606
1671 56990-56998 Species denotes patients Tax:9606
1672 57004-57012 Species denotes MERS-CoV Tax:1335626
1673 57014-57022 Species denotes SARS-CoV Tax:694009
1674 56562-56580 Chemical denotes methylprednisolone MESH:D008775
1675 56468-56476 Disease denotes COVID-19 MESH:C000657245
1676 56491-56526 Disease denotes acute respiratory distress syndrome MESH:D012128
1677 56528-56532 Disease denotes ARDS MESH:D012128
1678 56624-56629 Disease denotes death MESH:D003643
1679 57034-57050 Disease denotes viral infections MESH:D001102
1693 57067-57075 Species denotes patients Tax:9606
1694 57147-57155 Species denotes patients Tax:9606
1695 57161-57169 Species denotes SARS-CoV Tax:694009
1696 57508-57516 Species denotes patients Tax:9606
1697 57522-57530 Species denotes SARS-CoV Tax:694009
1698 57210-57224 Chemical denotes hydrocortisone MESH:D006854
1699 57332-57346 Chemical denotes hydrocortisone MESH:D006854
1700 57132-57146 Disease denotes critically ill MESH:D016638
1701 57257-57265 Disease denotes viraemia
1702 57315-57324 Disease denotes infection MESH:D007239
1703 57637-57655 Disease denotes avascular necrosis MESH:D010020
1704 57657-57666 Disease denotes psychosis MESH:D011605
1705 57668-57676 Disease denotes diabetes MESH:D003920
1721 57729-57737 Species denotes patients Tax:9606
1722 58224-58232 Species denotes patients Tax:9606
1723 58293-58301 Species denotes Patients Tax:9606
1724 58268-58281 Chemical denotes dexamethasone MESH:D003907
1725 58328-58341 Chemical denotes dexamethasone MESH:D003907
1726 58529-58542 Chemical denotes dexamethasone MESH:D003907
1727 58794-58807 Chemical denotes dexamethasone MESH:D003907
1728 57714-57728 Disease denotes critically ill MESH:D016638
1729 57787-57811 Disease denotes inflammation–coagulation MESH:D001778
1730 57847-57882 Disease denotes acute respiratory distress syndrome MESH:D012128
1731 57884-57888 Disease denotes ARDS MESH:D012128
1732 57957-57961 Disease denotes ARDS MESH:D012128
1733 58053-58065 Disease denotes inflammation MESH:D007249
1734 58238-58242 Disease denotes ARDS MESH:D012128
1735 58654-58663 Disease denotes mortality MESH:D003643
1752 58895-58903 Species denotes patients Tax:9606
1753 58909-58917 Species denotes SARS-CoV Tax:694009
1754 59073-59081 Species denotes patients Tax:9606
1755 59433-59441 Species denotes patients Tax:9606
1756 59447-59455 Species denotes MERS-CoV Tax:1335626
1757 59679-59687 Species denotes MERS-CoV Tax:1335626
1758 59701-59709 Species denotes patients Tax:9606
1759 59488-59502 Chemical denotes hydrocortisone MESH:D006854
1760 58880-58894 Disease denotes critically ill MESH:D016638
1761 58924-58942 Disease denotes MERS-CoV infection MESH:D018352
1762 59042-59056 Disease denotes CoV-1–infected MESH:D018352
1763 59058-59072 Disease denotes critically ill MESH:D016638
1764 59126-59135 Disease denotes mortality MESH:D003643
1765 59275-59295 Disease denotes secondary infections MESH:D060085
1766 59418-59432 Disease denotes critically ill MESH:D016638
1767 59584-59593 Disease denotes mortality MESH:D003643
1776 59824-59832 Species denotes patients Tax:9606
1777 59925-59933 Species denotes patients Tax:9606
1778 60197-60205 Species denotes patients Tax:9606
1779 59838-59847 Species denotes influenza Tax:11520
1780 59756-59772 Disease denotes viral infections MESH:D001102
1781 59848-59857 Disease denotes pneumonia MESH:D011014
1782 59954-59963 Disease denotes mortality MESH:D003643
1783 60122-60151 Disease denotes bacterial or fungal infection MESH:D001424
1803 60381-60389 Species denotes patients Tax:9606
1804 60558-60566 Species denotes patients Tax:9606
1805 60572-60582 Species denotes SARS-CoV-2 Tax:2697049
1806 60767-60775 Species denotes patients Tax:9606
1807 60894-60902 Species denotes patients Tax:9606
1808 61265-61273 Species denotes patients Tax:9606
1809 61139-61146 Chemical denotes steroid MESH:D013256
1810 61211-61218 Chemical denotes steroid MESH:D013256
1811 60395-60415 Disease denotes SARS-CoV-2 infection MESH:C000657245
1812 60623-60635 Disease denotes inflammation MESH:D007249
1813 60657-60668 Disease denotes lung injury MESH:D055370
1814 60718-60727 Disease denotes pneumonia MESH:D011014
1815 60758-60766 Disease denotes COVID-19 MESH:C000657245
1816 60870-60884 Disease denotes critically ill MESH:D016638
1817 60885-60893 Disease denotes COVID-19 MESH:C000657245
1818 60908-60912 Disease denotes ARDS MESH:D012128
1819 60938-60962 Disease denotes ARDS respiratory failure MESH:D012131
1820 61237-61255 Disease denotes non–critically ill MESH:D016638
1821 61256-61264 Disease denotes COVID-19 MESH:C000657245
1830 61410-61418 Species denotes patients Tax:9606
1831 61424-61432 Disease denotes COVID-19 MESH:C000657245
1832 61445-61490 Disease denotes secondary haemophagocytic lymphohistiocytosis MESH:D060085
1833 61511-61537 Disease denotes hyperinflammatory syndrome MESH:D061325
1834 61577-61594 Disease denotes hypercytokinaemia
1835 61616-61620 Disease denotes ARDS MESH:D012128
1836 61625-61643 Disease denotes multiorgan failure MESH:D009102
1837 61753-61761 Disease denotes COVID-19 MESH:C000657245
1859 62722-62740 Gene denotes C-reactive protein Gene:1401
1860 63107-63111 Gene denotes IL-6 Gene:3569
1861 63437-63441 Gene denotes IL-6 Gene:3569
1862 61956-61964 Species denotes patients Tax:9606
1863 62048-62056 Species denotes patients Tax:9606
1864 62414-62422 Species denotes patients Tax:9606
1865 63063-63071 Species denotes patients Tax:9606
1866 63622-63630 Species denotes patients Tax:9606
1867 61792-61803 Chemical denotes Tocilizumab MESH:C502936
1868 62181-62192 Chemical denotes tocilizumab MESH:C502936
1869 62428-62439 Chemical denotes tocilizumab MESH:C502936
1870 62888-62899 Chemical denotes tocilizumab MESH:C502936
1871 62959-62970 Chemical denotes Tocilizumab MESH:C502936
1872 63369-63380 Chemical denotes tocilizumab MESH:C502936
1873 63598-63609 Chemical denotes tocilizumab MESH:C502936
1874 61970-61990 Disease denotes rheumatoid arthritis MESH:D001172
1875 61992-62012 Disease denotes giant-cell arteritis MESH:D013700
1876 62014-62043 Disease denotes juvenile idiopathic arthritis MESH:D001171
1877 62405-62413 Disease denotes COVID-19 MESH:C000657245
1878 63084-63092 Disease denotes COVID-19 MESH:C000657245
1879 63613-63621 Disease denotes COVID-19 MESH:C000657245
1883 63692-63725 Gene denotes interleukin 1 receptor antagonist Gene:3557
1884 63829-63837 Species denotes patients Tax:9606
1885 63809-63828 Disease denotes SARS-CoV-2–infected MESH:C000657245
1895 66369-66377 Species denotes patients Tax:9606
1900 66383-66391 Disease denotes COVID-19 MESH:C000657245
1903 71608-71616 Disease denotes COVID-19 MESH:C000657245
1906 65544-65552 Species denotes patients Tax:9606
1907 65732-65740 Disease denotes COVID-19 MESH:C000657245
1922 65928-65938 Species denotes SARS-CoV-2 Tax:2697049
1923 66005-66015 Species denotes SARS-CoV-2 Tax:2697049
1924 66037-66045 Species denotes SARS-CoV Tax:694009
1925 66216-66226 Species denotes SARS-CoV-2 Tax:2697049
1927 66052-66061 Species denotes influenza Tax:11520
1928 66287-66294 Chemical denotes LPV/RTV MESH:C558899
1929 66358-66365 Chemical denotes LPV/RTV MESH:C558899
1930 66683-66690 Chemical denotes LPV/RTV MESH:C558899
1931 66884-66891 Chemical denotes LPV/RTV MESH:C558899
1932 67086-67093 Chemical denotes LPV/RTV MESH:C558899
1933 66101-66110 Disease denotes mortality MESH:D003643
1935 67131-67139 Disease denotes COVID-19 MESH:C000657245
1952 67457-67465 Species denotes patients Tax:9606
1953 67513-67521 Species denotes patients Tax:9606
1954 67942-67950 Species denotes patients Tax:9606
1955 68137-68145 Species denotes patients Tax:9606
1956 68158-68166 Species denotes patients Tax:9606
1957 67222-67233 Chemical denotes chloroquine MESH:D002738
1958 67234-67252 Chemical denotes hydroxychloroquine MESH:D006886
1959 67640-67658 Chemical denotes hydroxychloroquine MESH:D006886
1960 67819-67826 Chemical denotes steroid MESH:D013256
1961 68030-68037 Chemical denotes steroid MESH:D013256
1962 67477-67503 Disease denotes respiratory tract symptoms MESH:D012140
1963 67533-67559 Disease denotes respiratory tract symptoms MESH:D012140
1964 67917-67931 Disease denotes critically ill MESH:D016638
1965 67937-67941 Disease denotes ARDS MESH:D012128
1966 68132-68136 Disease denotes ARDS MESH:D012128
1967 68153-68157 Disease denotes ARDS MESH:D012128
1990 68362-68369 Species denotes patient Tax:9606
1991 68620-68628 Species denotes patients Tax:9606
1992 68754-68762 Species denotes patients Tax:9606
1993 68874-68882 Species denotes patients Tax:9606
1994 68884-68892 Species denotes patients Tax:9606
1995 69041-69049 Species denotes patients Tax:9606
1996 69223-69231 Species denotes patients Tax:9606
1997 69449-69457 Species denotes patients Tax:9606
1998 68790-68799 Species denotes influenza Tax:11520
1999 68290-68296 Chemical denotes oxygen MESH:D010100
2000 68728-68739 Chemical denotes oseltamivir MESH:D053139
2001 69159-69177 Chemical denotes hydroxychloroquine MESH:D006886
2003 68434-68442 Disease denotes asthenia MESH:D001247
2004 68449-68454 Disease denotes fever MESH:D005334
2005 68467-68472 Disease denotes cough MESH:D003371
2006 68634-68654 Disease denotes SARS-CoV-2 infection MESH:C000657245
2007 68898-68902 Disease denotes ARDS MESH:D012128
2008 68928-68952 Disease denotes ARDS respiratory failure MESH:D012131
2009 69032-69040 Disease denotes COVID-19 MESH:C000657245
2010 69214-69222 Disease denotes COVID-19 MESH:C000657245
2011 69379-69387 Disease denotes toxicity MESH:D064420
2017 69893-69904 Chemical denotes chloroquine MESH:D002738
2018 69905-69923 Chemical denotes hydroxychloroquine MESH:D006886
2019 70291-70298 Chemical denotes steroid MESH:D013256
2020 70368-70375 Chemical denotes steroid MESH:D013256
2021 70204-70213 Disease denotes mortality MESH:D003643
2030 70726-70734 Species denotes patients Tax:9606
2031 71309-71316 Species denotes patient Tax:9606
2032 70454-70465 Chemical denotes Chloroquine MESH:D002738
2033 70466-70484 Chemical denotes hydroxychloroquine MESH:D006886
2034 70924-70934 Chemical denotes remdesivir MESH:C000606551
2035 71378-71385 Chemical denotes steroid MESH:D013256
2036 70717-70725 Disease denotes COVID-19 MESH:C000657245
2037 70846-70887 Disease denotes QT prolongation or hepatic/renal toxicity MESH:D056486
2046 74876-74884 Species denotes patients Tax:9606
2051 74437-74445 Disease denotes COVID-19 MESH:C000657245
2052 74867-74875 Disease denotes COVID-19 MESH:C000657245
2061 73961-73974 Species denotes coronaviruses Tax:11118
2062 73980-73988 Species denotes patients Tax:9606
2063 74139-74147 Species denotes patients Tax:9606
2064 74311-74319 Species denotes patients Tax:9606
2065 73904-73911 Chemical denotes LPV/RTV MESH:C558899
2066 74291-74298 Chemical denotes LPV/RTV MESH:C558899
2067 74302-74310 Disease denotes COVID-19 MESH:C000657245
2072 74626-74634 Species denotes patients Tax:9606

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 9263-9271 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T2 9280-9284 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T3 11227-11242 Body_part denotes immunoglobulins http://purl.org/sig/ont/fma/fma62871
T4 11246-11252 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T5 11800-11804 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T6 13679-13683 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T7 14635-14638 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T8 16937-16941 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T9 17017-17021 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 17079-17083 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T11 17677-17683 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T12 19972-19976 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T13 20839-20842 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T14 20853-20856 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T15 20883-20886 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T16 22506-22509 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T17 22806-22812 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T18 22820-22826 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T19 22830-22853 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662
T20 22902-22905 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T21 22916-22919 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T22 24527-24533 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T23 25985-25994 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T24 26027-26031 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T25 26079-26083 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T26 29069-29075 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T27 29335-29338 Body_part denotes IgM http://purl.org/sig/ont/fma/fma62873
T28 29397-29400 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T29 29804-29812 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T30 29965-29973 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T31 30161-30165 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T32 30940-30942 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T33 30956-30964 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T34 31156-31164 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T35 31219-31221 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T36 31235-31237 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T37 31335-31343 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T38 32698-32711 Body_part denotes interleukin 6 http://purl.org/sig/ont/fma/fma264829
T39 32698-32709 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T40 32734-32742 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T41 33005-33009 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T42 33005-33007 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T43 33594-33600 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T44 33644-33648 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T45 33644-33646 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T46 33659-33663 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T47 33659-33661 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T48 33745-33753 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T49 33858-33866 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T50 34067-34071 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T51 34067-34069 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T52 34826-34840 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T53 34842-34846 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T54 34842-34844 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T55 34848-34861 Body_part denotes interleukin 1 http://purl.org/sig/ont/fma/fma86583
T56 34848-34859 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T57 35344-35348 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T58 35974-35983 Body_part denotes capillary http://purl.org/sig/ont/fma/fma63194
T59 38086-38090 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T60 38400-38404 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T61 39093-39097 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T62 40374-40377 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T63 40446-40451 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T64 41459-41462 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T65 42693-42698 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T66 42829-42834 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T67 42877-42900 Body_part denotes Upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T68 42987-42992 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T69 43042-43046 Body_part denotes Skin http://purl.org/sig/ont/fma/fma7163
T70 43576-43581 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T71 43620-43623 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T72 43834-43845 Body_part denotes Oral mucosa http://purl.org/sig/ont/fma/fma59660
T73 43839-43845 Body_part denotes mucosa http://purl.org/sig/ont/fma/fma85355
T74 44090-44098 Body_part denotes Antibody http://purl.org/sig/ont/fma/fma62871
T75 44160-44168 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T76 44347-44355 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T77 44566-44573 Body_part denotes alanine http://purl.org/sig/ont/fma/fma82749
T78 44661-44664 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T79 44666-44689 Body_part denotes low-density lipoprotein http://purl.org/sig/ont/fma/fma63170
T80 44693-44698 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T81 44967-44972 Body_part denotes joint http://purl.org/sig/ont/fma/fma7490
T82 45018-45028 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T83 46343-46346 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T84 46357-46360 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T85 48610-48614 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T86 48708-48716 Body_part denotes endosome http://purl.org/sig/ont/fma/fma67180
T87 48770-48778 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T88 48955-48966 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T89 48968-48970 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T90 49138-49143 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T91 58096-58101 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T92 58315-58318 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890
T93 59688-59691 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T94 59711-59728 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T95 60640-60648 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T96 60657-60661 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T97 61842-61850 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T98 61889-61891 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T99 61998-62002 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T100 62090-62094 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T101 62130-62138 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T102 62215-62223 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T103 62255-62263 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T104 62568-62572 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T105 62613-62618 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T106 62668-62678 Body_part denotes lymphocyte http://purl.org/sig/ont/fma/fma62863
T107 62733-62740 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T108 63107-63109 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T109 63437-63439 Body_part denotes IL http://purl.org/sig/ont/fma/fma86578
T110 63692-63705 Body_part denotes interleukin 1 http://purl.org/sig/ont/fma/fma86583
T111 63692-63703 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T112 64033-64047 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T113 64064-64070 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T114 65500-65515 Body_part denotes immunoglobulins http://purl.org/sig/ont/fma/fma62871
T115 65519-65525 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T116 67471-67494 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T117 67527-67550 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662
T118 68512-68516 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T119 71345-71349 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 9280-9284 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 11671-11694 Body_part denotes respiratory or systemic http://purl.obolibrary.org/obo/UBERON_0001004
T3 11800-11804 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T4 13679-13683 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 16937-16941 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T6 17017-17021 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T7 17079-17083 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T8 17677-17683 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T9 19157-19162 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T10 19463-19468 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T11 19972-19976 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T12 21095-21100 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T13 21910-21915 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T14 22452-22457 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T15 22806-22812 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T16 22820-22826 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T17 22830-22853 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T18 22836-22853 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T19 24527-24533 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T20 28526-28531 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T21 29013-29018 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T22 29708-29713 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T23 30161-30165 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T24 31570-31575 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T25 31631-31636 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T26 32026-32031 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T27 33594-33600 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T28 35344-35348 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T29 35974-35983 Body_part denotes capillary http://purl.obolibrary.org/obo/UBERON_0001982
T30 38086-38090 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T31 38400-38404 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T32 39093-39097 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T33 40446-40451 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T34 40956-40961 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T35 41459-41462 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T36 42693-42698 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T37 42829-42834 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T38 42877-42900 Body_part denotes Upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T39 42883-42900 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T40 42987-42992 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T41 43042-43046 Body_part denotes Skin http://purl.obolibrary.org/obo/UBERON_0000014
T42 43576-43581 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T43 43839-43845 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T44 44693-44698 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T45 49138-49143 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T46 58096-58101 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T47 58315-58318 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460
T48 59711-59728 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T49 60657-60661 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T50 62613-62618 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T51 67471-67494 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T52 67477-67494 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T53 67527-67550 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T54 67533-67550 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T55 68384-68407 Body_part denotes respiratory or systemic http://purl.obolibrary.org/obo/UBERON_0001004
T56 68512-68516 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T57 71345-71349 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 514-533 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T2 2125-2144 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T3 4967-4986 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T4 7889-7898 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 8064-8073 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T6 8597-8606 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T7 8626-8635 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T8 9337-9346 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T9 9551-9570 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T10 11722-11730 Phenotype denotes asthenia http://purl.obolibrary.org/obo/HP_0025406
T11 11737-11742 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T12 11755-11760 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T13 12219-12238 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T14 13907-13927 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T15 15927-15937 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T16 16765-16774 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T17 16882-16887 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T18 16889-16894 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T19 16962-16967 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T20 16969-16974 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T21 17460-17469 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T22 17544-17549 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T23 18786-18795 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T24 19897-19902 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T25 21489-21494 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T26 22707-22716 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T27 25763-25772 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T28 29804-29818 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T29 29861-29870 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T30 32499-32505 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T31 33377-33386 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T32 33461-33466 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T33 33745-33770 Phenotype denotes cytokine-release syndrome http://purl.obolibrary.org/obo/HP_0033041
T34 34664-34684 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T35 35344-35356 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T36 35403-35412 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T37 35430-35449 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T38 35514-35533 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T39 35855-35874 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T40 35902-35907 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T41 37918-37937 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T42 38394-38411 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T43 39050-39070 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T44 39207-39226 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T45 42683-42712 Phenotype denotes increased serum triglycerides http://purl.obolibrary.org/obo/HP_0002155
T46 42767-42776 Phenotype denotes Diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T47 42860-42866 Phenotype denotes Nausea http://purl.obolibrary.org/obo/HP_0002018
T48 42877-42910 Phenotype denotes Upper respiratory tract infection http://purl.obolibrary.org/obo/HP_0002788
T49 42919-42933 Phenotype denotes Abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T50 42944-42952 Phenotype denotes Vomiting http://purl.obolibrary.org/obo/HP_0002013
T51 42962-42969 Phenotype denotes Fatigue http://purl.obolibrary.org/obo/HP_0012378
T52 43024-43032 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T53 43042-43051 Phenotype denotes Skin rash http://purl.obolibrary.org/obo/HP_0000988
T54 43060-43071 Phenotype denotes Neutropenia http://purl.obolibrary.org/obo/HP_0001875
T55 43092-43099 Phenotype denotes Anxiety http://purl.obolibrary.org/obo/HP_0000739
T56 43107-43115 Phenotype denotes Insomnia http://purl.obolibrary.org/obo/HP_0100785
T57 43155-43166 Phenotype denotes Retinopathy http://purl.obolibrary.org/obo/HP_0000488
T58 43275-43289 Phenotype denotes abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T59 43291-43300 Phenotype denotes diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T60 43302-43318 Phenotype denotes nausea, vomiting http://purl.obolibrary.org/obo/HP_0002017
T61 43320-43335 Phenotype denotes agranulocytosis http://purl.obolibrary.org/obo/HP_0012234
T62 43337-43347 Phenotype denotes leukopenia http://purl.obolibrary.org/obo/HP_0001882
T63 43349-43365 Phenotype denotes thrombocytopenia http://purl.obolibrary.org/obo/HP_0001873
T64 43400-43413 Phenotype denotes acute hepatic http://purl.obolibrary.org/obo/HP_0200119
T65 43422-43430 Phenotype denotes myopathy http://purl.obolibrary.org/obo/HP_0003198
T66 43432-43444 Phenotype denotes bronchospasm http://purl.obolibrary.org/obo/HP_0025428
T67 43455-43476 Phenotype denotes prolonged QT interval http://purl.obolibrary.org/obo/HP_0001657
T68 43610-43635 Phenotype denotes Increased LDL cholesterol http://purl.obolibrary.org/obo/HP_0003141
T69 43680-43691 Phenotype denotes Neutropenia http://purl.obolibrary.org/obo/HP_0001875
T70 43732-43740 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T71 43750-43762 Phenotype denotes Hypertension http://purl.obolibrary.org/obo/HP_0000822
T72 43772-43781 Phenotype denotes Dizziness http://purl.obolibrary.org/obo/HP_0002321
T73 43789-43803 Phenotype denotes Hypothyroidism http://purl.obolibrary.org/obo/HP_0000821
T74 43812-43826 Phenotype denotes Abdominal pain http://purl.obolibrary.org/obo/HP_0002027
T75 43849-43863 Phenotype denotes gastric ulcers http://purl.obolibrary.org/obo/HP_0002592
T76 44204-44212 Phenotype denotes Headache http://purl.obolibrary.org/obo/HP_0002315
T77 44217-44225 Phenotype denotes vomiting http://purl.obolibrary.org/obo/HP_0002013
T78 44237-44247 Phenotype denotes Arthralgia http://purl.obolibrary.org/obo/HP_0002829
T79 44259-44264 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T80 44308-44320 Phenotype denotes eosinophilia http://purl.obolibrary.org/obo/HP_0001880
T81 44322-44332 Phenotype denotes leukopenia http://purl.obolibrary.org/obo/HP_0001882
T82 44371-44377 Phenotype denotes Nausea http://purl.obolibrary.org/obo/HP_0002018
T83 44382-44391 Phenotype denotes diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T84 44931-44941 Phenotype denotes cellulitis http://purl.obolibrary.org/obo/HP_0100658
T85 44943-44952 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T86 48926-48931 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T87 53289-53298 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T88 54121-54130 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T89 54332-54341 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T90 54523-54532 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T91 54657-54667 Phenotype denotes pneumoniae http://purl.obolibrary.org/obo/HP_0002090
T92 55161-55170 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T93 55333-55342 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T94 55870-55879 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T95 55899-55908 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T96 56497-56517 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T97 57637-57655 Phenotype denotes avascular necrosis http://purl.obolibrary.org/obo/HP_0010885
T98 57657-57666 Phenotype denotes psychosis http://purl.obolibrary.org/obo/HP_0000709
T99 57853-57873 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T100 59848-59857 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T101 60718-60727 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T102 60943-60962 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T103 61970-61990 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T104 62003-62012 Phenotype denotes arteritis http://purl.obolibrary.org/obo/HP_0012089
T105 62014-62043 Phenotype denotes juvenile idiopathic arthritis http://purl.obolibrary.org/obo/HP_0005681
T106 62130-62155 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041
T107 62215-62240 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041
T108 68434-68442 Phenotype denotes asthenia http://purl.obolibrary.org/obo/HP_0025406
T109 68449-68454 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T110 68467-68472 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T111 68933-68952 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 71-79 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 229-276 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T3 278-286 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T4 316-340 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T5 342-350 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 508-533 Disease denotes acute respiratory failure http://purl.obolibrary.org/obo/MONDO_0001208|http://purl.obolibrary.org/obo/MONDO_0021113
T8 815-823 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 1341-1349 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 1791-1799 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1824-1871 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T12 1873-1881 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 1911-1935 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T14 1937-1945 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 2119-2144 Disease denotes acute respiratory failure http://purl.obolibrary.org/obo/MONDO_0001208|http://purl.obolibrary.org/obo/MONDO_0021113
T17 3087-3095 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 3456-3464 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 3855-3865 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T20 4473-4481 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T21 4622-4630 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T22 4967-4986 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T23 5535-5543 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 5882-5890 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 6132-6140 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 6551-6560 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T27 6738-6746 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 6926-6934 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 7889-7898 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T30 7906-7914 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 7923-7942 Disease denotes bacterial infection http://purl.obolibrary.org/obo/MONDO_0005113
T32 7933-7942 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T33 8058-8073 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T34 8064-8073 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T35 8359-8367 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 8517-8525 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T37 8597-8606 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T38 8626-8635 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T39 9041-9049 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 9052-9061 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T41 9195-9199 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T42 9246-9258 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T43 9285-9291 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T44 9337-9346 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T45 9377-9385 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 9493-9501 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 9516-9520 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T48 9546-9550 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T49 9551-9570 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T50 9868-9876 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T51 10070-10078 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 10234-10242 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T53 10450-10460 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T54 10564-10572 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T55 11416-11424 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T56 11921-11929 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T57 11932-11941 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 12077-12086 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T59 12184-12188 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T60 12214-12218 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T61 12219-12238 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T62 12318-12326 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T63 12500-12508 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T64 13055-13063 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T65 13895-13899 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T66 13901-13936 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T67 13907-13936 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T68 13938-13946 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T69 13948-13972 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T70 14178-14186 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 14190-14237 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T72 14190-14223 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T73 14429-14437 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 14522-14530 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T75 14840-14848 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T76 15723-15731 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T77 15918-15926 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 15927-15937 Disease denotes pneumoniae http://purl.obolibrary.org/obo/MONDO_0005249
T79 16252-16260 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T80 16497-16505 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T81 16756-16764 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T82 16765-16774 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T83 17197-17205 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 17321-17329 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 17451-17459 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 17460-17469 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T87 17600-17612 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T88 17877-17885 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T89 18159-18167 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T90 18451-18459 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T91 18777-18785 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 18786-18795 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T93 19035-19043 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T94 19131-19139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 19344-19352 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T96 19770-19778 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T97 19977-19989 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T98 20154-20162 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T99 20381-20389 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T100 20668-20676 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T101 20746-20754 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 20983-20991 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T103 21200-21208 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T104 21406-21414 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T105 21646-21654 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T106 21801-21809 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 22033-22041 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T108 22333-22341 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T109 22698-22706 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T110 22707-22716 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T111 22892-22901 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T112 23008-23016 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T113 23059-23067 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T114 23348-23356 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T115 23562-23570 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T116 23849-23857 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T117 23927-23935 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T118 24076-24084 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T119 24336-24344 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 24628-24636 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 24909-24917 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T122 25196-25204 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 25274-25282 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 25340-25349 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T125 25443-25451 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T126 25494-25502 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 25754-25762 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T128 25763-25772 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T129 26545-26553 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T130 26664-26672 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T131 26774-26782 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T132 26931-26939 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 27209-27217 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 27287-27295 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T135 27407-27415 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T136 27563-27571 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T137 27612-27620 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T138 27802-27810 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T139 27926-27934 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 28060-28068 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T141 28184-28192 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T142 28195-28204 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T143 28291-28299 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T144 28443-28451 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T145 28649-28657 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T146 28891-28899 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 28987-28995 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 29189-29197 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T149 29339-29347 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T150 29589-29597 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T151 29779-29787 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T152 29813-29827 Disease denotes storm syndrome http://purl.obolibrary.org/obo/MONDO_0008496
T153 29861-29870 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T154 29872-29876 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T155 30078-30086 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T156 30166-30172 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T157 30270-30278 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T158 30570-30578 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T159 30773-30781 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T160 31006-31014 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T161 31385-31393 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T162 31476-31484 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T163 31733-31741 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T164 31909-31917 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T165 32170-32178 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T166 32488-32505 Disease denotes metastatic cancer http://purl.obolibrary.org/obo/MONDO_0024880
T167 32499-32505 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T168 32510-32518 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T169 32797-32805 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T170 33143-33151 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T171 33368-33376 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T172 33377-33386 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T173 33517-33529 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T174 33906-33914 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T175 34205-34213 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T176 34404-34412 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 34558-34566 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T178 34651-34655 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T179 34658-34693 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T180 34664-34693 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T181 34720-34728 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T182 34730-34754 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T183 35078-35086 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T184 35090-35137 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T185 35090-35123 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T186 35313-35321 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T187 35344-35356 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T188 35403-35412 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T189 35430-35449 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T190 35514-35533 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T191 35551-35559 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T192 35645-35653 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T193 36794-36802 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T194 37184-37193 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T195 37918-37937 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T196 38162-38170 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T197 38222-38230 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T198 38394-38411 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T200 38405-38411 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T201 38429-38437 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T202 38805-38813 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T203 39207-39226 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T204 39777-39785 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T205 40101-40109 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T206 40500-40508 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T207 40711-40719 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T208 42049-42057 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T209 42597-42605 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T210 42767-42776 Disease denotes Diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T211 42883-42910 Disease denotes respiratory tract infection http://purl.obolibrary.org/obo/MONDO_0024355
T212 42901-42910 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T213 43042-43051 Disease denotes Skin rash http://purl.obolibrary.org/obo/MONDO_0006547
T214 43060-43071 Disease denotes Neutropenia http://purl.obolibrary.org/obo/MONDO_0001475
T215 43092-43099 Disease denotes Anxiety http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918
T217 43107-43115 Disease denotes Insomnia http://purl.obolibrary.org/obo/MONDO_0013600
T218 43155-43166 Disease denotes Retinopathy http://purl.obolibrary.org/obo/MONDO_0005283
T219 43249-43273 Disease denotes Stevens-Johnson syndrome http://purl.obolibrary.org/obo/MONDO_0018229
T220 43257-43273 Disease denotes Johnson syndrome http://purl.obolibrary.org/obo/MONDO_0019419
T221 43291-43300 Disease denotes diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T222 43320-43335 Disease denotes agranulocytosis http://purl.obolibrary.org/obo/MONDO_0001609
T223 43337-43347 Disease denotes leukopenia http://purl.obolibrary.org/obo/MONDO_0003785
T224 43349-43365 Disease denotes thrombocytopenia http://purl.obolibrary.org/obo/MONDO_0002049
T225 43422-43430 Disease denotes myopathy http://purl.obolibrary.org/obo/MONDO_0005336
T226 43432-43444 Disease denotes bronchospasm http://purl.obolibrary.org/obo/MONDO_0001358
T227 43680-43691 Disease denotes Neutropenia http://purl.obolibrary.org/obo/MONDO_0001475
T228 43750-43762 Disease denotes Hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T229 43789-43803 Disease denotes Hypothyroidism http://purl.obolibrary.org/obo/MONDO_0005420
T230 43849-43863 Disease denotes gastric ulcers http://purl.obolibrary.org/obo/MONDO_0001126
T231 43857-43863 Disease denotes ulcers http://purl.obolibrary.org/obo/MONDO_0043839
T232 43889-43901 Disease denotes Pneumocystis http://purl.obolibrary.org/obo/MONDO_0019121
T233 43917-43929 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T234 43934-43943 Disease denotes varicella http://purl.obolibrary.org/obo/MONDO_0005700
T235 43944-43950 Disease denotes zoster http://purl.obolibrary.org/obo/MONDO_0005609
T236 44308-44320 Disease denotes eosinophilia http://purl.obolibrary.org/obo/MONDO_0015691
T237 44322-44332 Disease denotes leukopenia http://purl.obolibrary.org/obo/MONDO_0003785
T238 44382-44391 Disease denotes diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T239 44498-44506 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T240 44625-44633 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T241 44635-44659 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T242 44911-44921 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T243 44931-44941 Disease denotes cellulitis http://purl.obolibrary.org/obo/MONDO_0005230
T244 44943-44952 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T245 44973-44983 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T246 45074-45079 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T247 45133-45141 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T248 45145-45153 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T249 45296-45304 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T250 45650-45659 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T251 45708-45716 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T252 45833-45841 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T253 45929-45937 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T254 45999-46008 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T255 46031-46040 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T256 46141-46149 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T257 46214-46223 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T258 46305-46313 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T259 46392-46401 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T260 46437-46446 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T261 46885-46893 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T262 46939-46947 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T263 47284-47292 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T264 47344-47352 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T265 47583-47591 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T266 47843-47851 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T267 48259-48268 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T268 48386-48394 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T269 48635-48643 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T270 48650-48658 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T271 48926-48931 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T272 49163-49171 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T273 49563-49571 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T274 49787-49795 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T275 50423-50431 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T276 50549-50557 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T277 52046-52054 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T278 52243-52251 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T279 53097-53117 Disease denotes Bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T280 53150-53158 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T281 53283-53298 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T282 53289-53298 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T283 53451-53474 Disease denotes bacterial infections in http://purl.obolibrary.org/obo/MONDO_0005113
T284 53489-53497 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T285 53554-53574 Disease denotes bacterial infections http://purl.obolibrary.org/obo/MONDO_0005113
T286 53701-53709 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T287 53958-53966 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T288 54121-54130 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T289 54237-54256 Disease denotes bacterial infection http://purl.obolibrary.org/obo/MONDO_0005113
T290 54247-54256 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T291 54322-54341 Disease denotes bacterial pneumonia http://purl.obolibrary.org/obo/MONDO_0004652
T292 54332-54341 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T293 54401-54410 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T294 54411-54426 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T295 54417-54426 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T296 54475-54484 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T297 54513-54532 Disease denotes bacterial pneumonia http://purl.obolibrary.org/obo/MONDO_0004652
T298 54523-54532 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T299 54643-54667 Disease denotes Streptococcus pneumoniae http://purl.obolibrary.org/obo/MONDO_0005972
T300 54681-54691 Disease denotes influenzae http://purl.obolibrary.org/obo/MONDO_0005812
T301 54808-54816 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T302 54977-54985 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T303 55161-55170 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T304 55178-55186 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T305 55195-55214 Disease denotes bacterial infection http://purl.obolibrary.org/obo/MONDO_0005113
T306 55205-55214 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T307 55327-55342 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T308 55333-55342 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T309 55632-55640 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T310 55790-55798 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T311 55870-55879 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T312 55899-55908 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T313 56268-56276 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T314 56381-56389 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T315 56468-56476 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T316 56491-56526 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T317 56497-56526 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T318 56528-56532 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T319 57014-57022 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T320 57034-57050 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T321 57161-57169 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T322 57315-57324 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T323 57522-57530 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T324 57637-57655 Disease denotes avascular necrosis http://purl.obolibrary.org/obo/MONDO_0005380|http://purl.obolibrary.org/obo/MONDO_0018373
T326 57657-57666 Disease denotes psychosis http://purl.obolibrary.org/obo/MONDO_0005485
T327 57668-57676 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T328 57787-57799 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T329 57847-57882 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T330 57853-57882 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T331 57884-57888 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T332 57957-57961 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T333 58053-58065 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T334 58238-58242 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T335 58909-58917 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T336 58933-58942 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T337 59037-59045 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T338 59285-59295 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T339 59756-59772 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T340 59838-59847 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T341 59848-59857 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T342 60135-60151 Disease denotes fungal infection http://purl.obolibrary.org/obo/MONDO_0002041
T343 60142-60151 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T344 60395-60403 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T345 60406-60415 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T346 60572-60580 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T347 60623-60635 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T348 60662-60668 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T349 60718-60727 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T350 60758-60766 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T351 60885-60893 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T352 60908-60912 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T353 60938-60942 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T354 60943-60962 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T355 61256-61264 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T356 61424-61432 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T357 61445-61490 Disease denotes secondary haemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015542
T358 61616-61620 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T359 61625-61643 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T360 61753-61761 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T361 61970-61990 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T362 61981-61990 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T363 61992-62012 Disease denotes giant-cell arteritis http://purl.obolibrary.org/obo/MONDO_0008538
T364 62003-62012 Disease denotes arteritis http://purl.obolibrary.org/obo/MONDO_0043494
T365 62014-62043 Disease denotes juvenile idiopathic arthritis http://purl.obolibrary.org/obo/MONDO_0011429
T366 62034-62043 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T367 62405-62413 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T368 63084-63092 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T369 63613-63621 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T370 63809-63817 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T371 64322-64330 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T372 64486-64494 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T373 64702-64712 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T374 64816-64824 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T375 65732-65740 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T376 65928-65936 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T377 66005-66013 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T378 66037-66045 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T379 66052-66061 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T380 66216-66224 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T381 66383-66391 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T382 67131-67139 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T383 67937-67941 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T384 68132-68136 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T385 68153-68157 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T386 68634-68642 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T387 68645-68654 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T388 68790-68799 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T389 68898-68902 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T390 68928-68932 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T391 68933-68952 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T392 69032-69040 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T393 69214-69222 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T394 70717-70725 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T395 71608-71616 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T396 71896-71904 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T397 74302-74310 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T398 74437-74445 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T399 74867-74875 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 359-362 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 733-743 http://purl.obolibrary.org/obo/BFO_0000030 denotes Objectives
T3 1175-1176 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 1247-1252 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T5 1954-1957 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T6 2221-2222 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 2263-2264 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 3097-3100 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T9 3174-3175 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 3424-3430 http://purl.obolibrary.org/obo/UBERON_0001456 denotes facing
T11 3499-3500 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 3598-3599 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T13 3753-3754 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 4074-4075 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 4210-4211 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 4235-4236 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T17 4410-4415 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T18 4504-4511 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T19 5204-5205 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 5561-5562 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 5850-5855 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T22 6900-6908 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T23 7027-7032 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T24 7048-7049 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 7416-7421 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T26 8028-8029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 8079-8080 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T28 8105-8106 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 9280-9284 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T30 9280-9284 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T31 9820-9821 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T32 10140-10145 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T33 10493-10494 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 10510-10515 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T35 10661-10662 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T36 10667-10671 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T37 10667-10671 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T38 10801-10802 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T39 11246-11252 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T40 11671-11694 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory or systemic
T41 11800-11804 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T42 11800-11804 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T43 13550-13551 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T44 13679-13683 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T45 13679-13683 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T46 13787-13788 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 14000-14006 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T48 14257-14269 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T49 14372-14377 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T50 14679-14680 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T51 14742-14747 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T52 15335-15339 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T53 15457-15458 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 15630-15632 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T55 15638-15640 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T56 15738-15743 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T57 15793-15798 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T58 15811-15815 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3, 5
T59 15831-15833 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T60 15944-15949 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T61 16051-16057 http://purl.obolibrary.org/obo/CLO_0001230 denotes 2 ≤ 93
T62 16051-16057 http://purl.obolibrary.org/obo/CLO_0037237 denotes 2 ≤ 93
T63 16051-16057 http://purl.obolibrary.org/obo/CLO_0050903 denotes 2 ≤ 93
T64 16051-16057 http://purl.obolibrary.org/obo/CLO_0054249 denotes 2 ≤ 93
T65 16051-16057 http://purl.obolibrary.org/obo/CLO_0054250 denotes 2 ≤ 93
T66 16051-16057 http://purl.obolibrary.org/obo/CLO_0054251 denotes 2 ≤ 93
T67 16051-16057 http://purl.obolibrary.org/obo/CLO_0054252 denotes 2 ≤ 93
T68 16267-16272 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T69 16330-16335 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T70 16512-16517 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T71 16781-16786 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T72 16838-16839 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 16937-16941 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T74 16937-16941 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T75 17017-17021 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T76 17017-17021 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T77 17030-17036 http://purl.obolibrary.org/obo/CLO_0001230 denotes 2 > 93
T78 17030-17036 http://purl.obolibrary.org/obo/CLO_0037237 denotes 2 > 93
T79 17030-17036 http://purl.obolibrary.org/obo/CLO_0050903 denotes 2 > 93
T80 17030-17036 http://purl.obolibrary.org/obo/CLO_0054249 denotes 2 > 93
T81 17030-17036 http://purl.obolibrary.org/obo/CLO_0054250 denotes 2 > 93
T82 17030-17036 http://purl.obolibrary.org/obo/CLO_0054251 denotes 2 > 93
T83 17030-17036 http://purl.obolibrary.org/obo/CLO_0054252 denotes 2 > 93
T84 17068-17069 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T85 17079-17083 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T86 17079-17083 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T87 17291-17292 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 17476-17481 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T89 17541-17542 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 17587-17588 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T91 17814-17815 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 17892-17897 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T93 18174-18179 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T94 18466-18471 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T95 18870-18871 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 18901-18902 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T97 19445-19448 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T98 19852-19853 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 19894-19895 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T100 19972-19976 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T101 19972-19976 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T102 20169-20174 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T103 20683-20688 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T104 21421-21426 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T105 21661-21666 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T106 21892-21895 http://purl.obolibrary.org/obo/CLO_0050154 denotes a 8
T107 22048-22053 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T108 22434-22437 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T109 22551-22552 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 22723-22728 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T111 22830-22853 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T112 22946-22947 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T113 22972-22973 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T114 23235-23239 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T115 23235-23239 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T116 23363-23368 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T117 23864-23869 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T118 24091-24096 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T119 24193-24194 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 24410-24411 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T121 24502-24503 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T122 24643-24648 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T123 24725-24729 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T124 25211-25216 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T125 25350-25358 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T126 25381-25382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 25407-25408 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 25670-25674 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T129 25670-25674 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T130 25779-25784 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T131 25842-25847 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T132 26016-26021 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T133 26027-26031 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T134 26079-26083 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T135 26112-26120 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T136 26264-26265 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T137 26338-26343 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T138 26418-26419 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T139 26480-26481 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T140 26946-26951 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T141 27011-27012 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T142 27058-27059 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T143 27224-27229 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T144 27320-27325 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T145 27542-27543 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 27583-27585 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T147 27595-27596 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T148 27632-27634 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T149 27677-27679 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T150 27722-27724 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T151 28154-28155 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 28415-28416 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T153 28486-28487 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T154 28508-28511 http://purl.obolibrary.org/obo/CLO_0001577 denotes a 3
T155 28664-28669 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T156 29069-29075 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T157 29204-29209 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T158 29269-29270 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 29282-29287 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T160 29322-29323 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T161 29690-29693 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T162 29744-29745 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T163 29802-29803 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T164 30093-30098 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T165 30161-30165 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T166 30161-30165 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T167 30285-30290 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T168 30788-30793 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T169 30845-30846 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T170 30879-30880 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T171 31021-31026 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T172 31130-31139 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Humanized
T173 31192-31200 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T174 31357-31360 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T175 31491-31496 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T176 31612-31616 http://purl.obolibrary.org/obo/CLO_0001550 denotes a 10
T177 31748-31753 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T178 32008-32011 http://purl.obolibrary.org/obo/CLO_0001608 denotes a 7
T179 32185-32190 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T180 32250-32251 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T181 32297-32298 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T182 32525-32530 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T183 32698-32711 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin 6
T184 32812-32817 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T185 33158-33163 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T186 33393-33398 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T187 33458-33459 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T188 33504-33505 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T189 33921-33926 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T190 34220-34225 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T191 34337-34342 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T192 34848-34861 http://purl.obolibrary.org/obo/PR_000001091 denotes interleukin 1
T193 34957-34965 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T194 34957-34965 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T195 35157-35169 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T196 35342-35343 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T197 35344-35348 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T198 35344-35348 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T199 36140-36142 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T200 36304-36305 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T201 36337-36338 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 37002-37003 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T203 37134-37135 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T204 37222-37223 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 37399-37405 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T206 37639-37647 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T207 37639-37647 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T208 37716-37719 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T209 37720-37721 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T210 38028-38031 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T211 38086-38090 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T212 38086-38090 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T213 38274-38275 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T214 38400-38404 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T215 38400-38404 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T216 38468-38469 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 38561-38562 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T218 39093-39097 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T219 39093-39097 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T220 39111-39113 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T221 39446-39447 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T222 39803-39804 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T223 40084-40092 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T224 40327-40328 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T225 40483-40491 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T226 40587-40593 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T227 40740-40745 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T228 40760-40762 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T229 40856-40857 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T230 40931-40932 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T231 41097-41101 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T232 41401-41402 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T233 41459-41462 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T234 41514-41518 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arms
T235 41633-41634 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 41732-41737 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T237 42350-42351 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T238 42554-42559 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T239 42846-42849 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3/4
T240 42853-42855 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T241 42937-42939 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T242 42954-42957 http://purl.obolibrary.org/obo/CLO_0050509 denotes 2–7
T243 43042-43046 http://purl.obolibrary.org/obo/UBERON_0000014 denotes Skin
T244 43042-43046 http://purl.obolibrary.org/obo/UBERON_0001003 denotes Skin
T245 43042-43046 http://purl.obolibrary.org/obo/UBERON_0002097 denotes Skin
T246 43042-43046 http://purl.obolibrary.org/obo/UBERON_0002199 denotes Skin
T247 43042-43046 http://www.ebi.ac.uk/efo/EFO_0000962 denotes Skin
T248 43079-43082 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3/4
T249 43191-43192 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T250 43393-43398 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T251 43588-43590 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T252 43603-43605 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T253 43702-43705 http://purl.obolibrary.org/obo/CLO_0050509 denotes 2–7
T254 43839-43845 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
T255 44010-44013 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T256 44083-44085 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T257 44431-44436 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T258 44691-44692 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T259 44832-44833 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T260 44958-44962 http://purl.obolibrary.org/obo/UBERON_0002481 denotes bone
T261 44967-44972 http://purl.obolibrary.org/obo/UBERON_0000982 denotes joint
T262 44967-44972 http://purl.obolibrary.org/obo/UBERON_0004905 denotes joint
T263 45101-45109 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T264 45196-45202 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T265 45681-45687 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T266 45758-45766 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T267 45796-45799 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T268 45854-45856 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T269 46402-46410 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T270 46447-46455 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T271 46790-46794 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T272 46790-46794 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T273 46858-46859 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T274 47327-47335 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T275 47364-47367 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T276 47551-47556 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T277 48479-48487 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T278 48543-48551 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T279 48565-48568 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T280 48599-48606 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T281 48610-48614 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T282 48702-48707 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T283 48840-48842 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T284 48846-48848 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T285 48926-48953 http://purl.obolibrary.org/obo/PR_000000134 denotes tumor necrosis factor alpha
T286 49138-49143 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T287 49314-49315 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T288 49546-49554 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T289 50057-50060 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T290 50381-50382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T291 50473-50476 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T292 50502-50504 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T293 50642-50643 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T294 51180-51185 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T295 51198-51199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T296 51271-51272 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T297 51402-51407 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T298 51478-51479 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T299 51500-51502 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T300 52217-52225 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T301 52344-52349 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T302 52365-52366 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T303 52732-52737 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T304 53601-53609 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T305 54144-54151 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T306 54155-54156 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T307 54275-54277 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T308 54292-54294 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T309 54411-54416 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T310 54549-54557 http://purl.obolibrary.org/obo/NCBITaxon_2 denotes bacteria
T311 54702-54703 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T312 55378-55379 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T313 56198-56201 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T314 57109-57110 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T315 57187-57188 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T316 57414-57415 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T317 57689-57694 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T318 57916-57917 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T319 58006-58007 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T320 58096-58101 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T321 58186-58187 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T322 58315-58318 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T323 58460-58461 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T324 58627-58628 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T325 58994-58995 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T326 59375-59376 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T327 59479-59480 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T328 59561-59562 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T329 59798-59799 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T330 59869-59872 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T331 59900-59901 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T332 60437-60449 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T333 60657-60661 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T334 60657-60661 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T335 61555-61556 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T336 61807-61808 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T337 61821-61830 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humanized
T338 61862-61870 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T339 61998-62002 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T340 62088-62094 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T341 62324-62325 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T342 62360-62362 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T343 62462-62466 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T344 62462-62466 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T345 62552-62553 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T346 62601-62602 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T347 62613-62618 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T348 62613-62618 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T349 62971-62974 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T350 63031-63032 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T351 63234-63235 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T352 63276-63277 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T353 63381-63384 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T354 63429-63430 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T355 63692-63705 http://purl.obolibrary.org/obo/PR_000001091 denotes interleukin 1
T356 64064-64070 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T357 64392-64397 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T358 64745-64746 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T359 64762-64767 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T360 64919-64920 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T361 64925-64929 http://purl.obolibrary.org/obo/CLO_0008416 denotes peer
T362 64925-64929 http://purl.obolibrary.org/obo/CLO_0050081 denotes peer
T363 65060-65061 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T364 65519-65525 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T365 65909-65916 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T366 66069-66070 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T367 66507-66509 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T368 66600-66602 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T369 67368-67373 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T370 67412-67414 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T371 67432-67433 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T372 67527-67550 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T373 67613-67614 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T374 67872-67873 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T375 67985-67986 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T376 68384-68407 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory or systemic
T377 68512-68516 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T378 68512-68516 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T379 69743-69744 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T380 69771-69779 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T381 69877-69878 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T382 71225-71226 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T383 71345-71349 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T384 71345-71349 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T385 71450-71451 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T386 71876-71882 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T387 72825-72830 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T388 73230-73235 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T389 73694-73699 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T390 73914-73915 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T391 73944-73952 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T392 73977-73978 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T393 74067-74072 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T394 74256-74257 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T395 74272-74277 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T396 74343-74348 http://purl.obolibrary.org/obo/CLO_0007225 denotes label

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1247-1252 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T2 1253-1262 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T3 1267-1290 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T4 1285-1290 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T5 1624-1630 Chemical denotes Access http://purl.obolibrary.org/obo/CHEBI_34922
T6 2883-2889 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T7 4410-4415 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T8 4434-4439 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T9 4817-4823 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T10 4912-4918 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T11 5206-5210 Chemical denotes PEEP http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683
T13 5239-5244 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T14 5295-5301 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T15 5736-5752 Chemical denotes antiviral agents http://purl.obolibrary.org/obo/CHEBI_22587
T16 5850-5855 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T17 5953-5972 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T19 5962-5972 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T20 5979-5988 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T21 6089-6099 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T22 6309-6320 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T23 6325-6335 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T24 6454-6465 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T25 6469-6478 Chemical denotes zanamivir http://purl.obolibrary.org/obo/CHEBI_50663
T26 6581-6592 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T27 6593-6611 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T28 6664-6682 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T29 6768-6772 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T30 7281-7299 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T31 7416-7421 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T32 7579-7597 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T33 7751-7762 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T34 7836-7846 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T35 8301-8314 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T36 8656-8675 Chemical denotes antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_33281
T37 8729-8739 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T38 8883-8891 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T39 8994-9008 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T40 9155-9169 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T41 9459-9474 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T42 9746-9753 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T43 9823-9830 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T44 10041-10052 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T45 10140-10145 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T46 10510-10515 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T47 10523-10534 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T48 11108-11125 Chemical denotes enzyme inhibitors http://purl.obolibrary.org/obo/CHEBI_23924
T49 11115-11125 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T50 11579-11585 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T51 11860-11869 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T52 12015-12026 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T53 12445-12463 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T54 12680-12698 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T55 12800-12811 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T56 12812-12830 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T57 13253-13263 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T58 13509-13524 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T59 13715-13722 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T60 13806-13820 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T61 14083-14102 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T62 14083-14092 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T63 14093-14102 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T64 14104-14108 Chemical denotes PEEP http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683
T66 14327-14350 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T67 14345-14350 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T68 14372-14377 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T69 14599-14608 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T70 14609-14618 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T71 14619-14628 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T72 14646-14664 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T74 14655-14664 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T75 14681-14697 Chemical denotes CYP3A4 inhibitor http://purl.obolibrary.org/obo/CHEBI_86501
T76 14688-14697 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T77 14710-14719 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T78 14742-14747 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T79 14762-14781 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T80 14762-14771 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T81 14772-14781 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T82 14859-14868 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T83 14869-14878 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T84 15430-15449 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T85 15430-15439 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T86 15440-15449 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T87 15658-15677 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T88 15658-15667 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T89 15668-15677 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T90 15682-15700 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T91 15738-15743 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T92 15857-15866 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T93 15871-15890 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T94 15871-15880 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T95 15881-15890 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T96 15944-15949 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T97 16067-16073 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T98 16110-16112 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T100 16175-16194 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T101 16175-16184 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T102 16185-16194 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T103 16199-16218 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T104 16199-16208 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T105 16209-16218 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T106 16224-16234 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T107 16267-16272 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T108 16397-16416 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T109 16397-16406 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T110 16407-16416 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T111 16421-16440 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T112 16421-16430 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T113 16431-16440 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T114 16446-16455 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T115 16461-16471 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T116 16472-16476 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T117 16512-16517 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T118 16678-16697 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T119 16678-16687 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T120 16688-16697 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T121 16702-16713 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T122 16718-16728 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T123 16781-16786 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T124 17062-17064 Chemical denotes Hg http://purl.obolibrary.org/obo/CHEBI_16170|http://purl.obolibrary.org/obo/CHEBI_25195
T126 17132-17151 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T127 17132-17141 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T128 17142-17151 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T129 17385-17404 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T130 17385-17394 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T131 17395-17404 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T132 17408-17418 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T133 17422-17433 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T134 17476-17481 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T135 17720-17739 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T136 17720-17729 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T137 17730-17739 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T138 17744-17763 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T139 17744-17753 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T140 17754-17763 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T141 17850-17858 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T142 17892-17897 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T143 18015-18034 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T144 18015-18024 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T145 18025-18034 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T146 18048-18058 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T147 18068-18087 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T148 18068-18077 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T149 18078-18087 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T150 18101-18111 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T151 18174-18179 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T152 18297-18316 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T153 18297-18306 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T154 18307-18316 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T155 18330-18340 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T156 18350-18369 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T157 18350-18359 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T158 18360-18369 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T159 18383-18393 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T160 18466-18471 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T161 18597-18616 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T162 18597-18606 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T163 18607-18616 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T164 18622-18640 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T165 18645-18664 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T166 18645-18654 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T167 18655-18664 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T168 18670-18688 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T169 18694-18704 Chemical denotes levamisole http://purl.obolibrary.org/obo/CHEBI_6432
T170 18715-18725 Chemical denotes budesonide http://purl.obolibrary.org/obo/CHEBI_3207
T171 18731-18741 Chemical denotes formoterol http://purl.obolibrary.org/obo/CHEBI_5147
T172 18949-18968 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T173 18949-18958 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T174 18959-18968 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T175 18973-18991 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T176 18996-19004 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T177 19200-19219 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T178 19200-19209 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T179 19210-19219 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T180 19224-19242 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T181 19247-19266 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T182 19247-19256 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T183 19257-19266 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T184 19272-19282 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T185 19283-19287 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T186 19295-19305 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T187 19496-19515 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T188 19496-19505 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T189 19506-19515 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T190 19519-19529 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T191 19533-19544 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T192 19548-19566 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T193 19570-19581 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T194 19599-19611 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T195 19636-19655 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T196 19636-19645 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T197 19646-19655 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T198 19659-19669 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T199 19673-19684 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T200 19688-19706 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T201 19710-19721 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T202 19739-19751 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T203 20042-20052 Chemical denotes colchicine http://purl.obolibrary.org/obo/CHEBI_23359
T204 20070-20089 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T205 20070-20079 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T206 20080-20089 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T207 20169-20174 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T208 20289-20300 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T209 20306-20317 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T210 20322-20333 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T211 20339-20358 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T212 20339-20348 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T213 20349-20358 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T214 20397-20416 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T215 20397-20406 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T216 20407-20416 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T217 20422-20433 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T218 20438-20447 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T219 20448-20457 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T220 20463-20474 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T221 20479-20490 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T222 20496-20515 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T223 20496-20505 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T224 20506-20515 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T225 20520-20529 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T226 20530-20539 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T227 20545-20556 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T228 20562-20573 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T229 20578-20587 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T230 20588-20597 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T231 20603-20614 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T232 20620-20631 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T233 20683-20688 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T234 20807-20816 Chemical denotes Adenosine http://purl.obolibrary.org/obo/CHEBI_16335
T235 20936-20946 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T236 21143-21153 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T237 21344-21354 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T238 21421-21426 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T239 21513-21519 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T240 21582-21592 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T241 21661-21666 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T242 21761-21771 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T243 21943-21953 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T244 21958-21976 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T245 21981-21991 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T246 21997-22015 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T247 22048-22053 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T248 22189-22208 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T249 22189-22198 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T250 22199-22208 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T251 22213-22231 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T252 22236-22255 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T253 22236-22245 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T254 22246-22255 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T255 22261-22271 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T256 22272-22276 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T257 22284-22294 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T258 22469-22478 Chemical denotes Darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T259 22479-22489 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T260 22490-22499 Chemical denotes Darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T261 22517-22535 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T263 22526-22535 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T264 22553-22569 Chemical denotes CYP3A4 inhibitor http://purl.obolibrary.org/obo/CHEBI_86501
T265 22560-22569 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T266 22582-22591 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T267 22639-22648 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T268 22649-22659 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T269 22723-22728 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T270 22916-22940 Chemical denotes RNA polymerase inhibitor http://purl.obolibrary.org/obo/CHEBI_37416
T271 22931-22940 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T272 23039-23050 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T273 23087-23097 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T274 23169-23180 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T275 23270-23281 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T276 23286-23297 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T277 23302-23313 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T278 23319-23330 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T279 23363-23368 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T280 23470-23481 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T281 23487-23498 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T282 23503-23514 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T283 23520-23539 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T284 23520-23529 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T285 23530-23539 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T286 23578-23597 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T287 23578-23587 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T288 23588-23597 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T289 23603-23614 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T290 23619-23628 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T291 23629-23638 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T292 23644-23655 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T293 23660-23671 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T294 23677-23696 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T295 23677-23686 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T296 23687-23696 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T297 23701-23710 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T298 23711-23720 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T299 23726-23737 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T300 23743-23754 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T301 23759-23768 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T302 23769-23778 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T303 23784-23795 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T304 23801-23812 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T305 23864-23869 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T306 23993-24011 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T307 24017-24026 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T308 24027-24037 Chemical denotes cobicistat http://purl.obolibrary.org/obo/CHEBI_72291
T309 24091-24096 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T310 24262-24273 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T311 24279-24290 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T312 24295-24306 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T313 24578-24589 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T314 24643-24648 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T315 24712-24724 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T316 24720-24724 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T317 24817-24828 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T318 24834-24845 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T319 24850-24861 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T320 24867-24886 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T321 24867-24876 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T322 24877-24886 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T323 24925-24944 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T324 24925-24934 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T325 24935-24944 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T326 24950-24961 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T327 24966-24975 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T328 24976-24985 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T329 24991-25002 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T330 25007-25018 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T331 25024-25043 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T332 25024-25033 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T333 25034-25043 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T334 25048-25057 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T335 25058-25067 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T336 25073-25084 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T337 25090-25101 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T338 25106-25115 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T339 25116-25125 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T340 25131-25142 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T341 25148-25159 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T342 25211-25216 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T343 25366-25375 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T344 25474-25485 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T345 25522-25532 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T346 25604-25615 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T347 25705-25715 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T348 25779-25784 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T349 25893-25904 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T350 25906-25924 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T351 25995-25997 Chemical denotes Ph http://purl.obolibrary.org/obo/CHEBI_30396
T352 26163-26181 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T353 26338-26343 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T354 26612-26630 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T355 26635-26648 Chemical denotes ascorbic acid http://purl.obolibrary.org/obo/CHEBI_22652|http://purl.obolibrary.org/obo/CHEBI_29073
T357 26644-26648 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T358 26820-26831 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T359 26837-26855 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T360 26861-26873 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T361 26878-26889 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T362 26895-26913 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T363 26946-26951 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T364 27157-27175 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T365 27224-27229 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T366 27359-27377 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T367 27458-27468 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T368 27749-27767 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T369 27995-28014 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T370 27995-28004 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T371 28005-28014 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T372 28245-28263 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T373 28559-28569 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T374 28574-28592 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T375 28597-28607 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T376 28613-28631 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T377 28664-28669 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T378 28805-28824 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T379 28805-28814 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T380 28815-28824 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T381 28829-28847 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T382 28852-28860 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T383 29081-29099 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T384 29105-29117 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T385 29122-29140 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T386 29146-29158 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T387 29204-29209 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T388 29445-29464 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T389 29445-29454 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T390 29455-29464 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T391 29469-29487 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T392 29492-29511 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T393 29492-29501 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T394 29502-29511 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T395 29517-29527 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T396 29528-29532 Chemical denotes beta http://purl.obolibrary.org/obo/CHEBI_10545
T397 29540-29550 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T398 29908-29923 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T399 30014-30032 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T400 30093-30098 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T401 30213-30231 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T402 30285-30290 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T403 30403-30408 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T404 30409-30419 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T405 30425-30443 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T406 30449-30459 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T407 30464-30475 Chemical denotes thalidomide http://purl.obolibrary.org/obo/CHEBI_9513
T408 30489-30494 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T409 30495-30505 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T410 30511-30529 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T411 30535-30545 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T412 30737-30755 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T413 30788-30793 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T414 30940-30942 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T416 30970-30988 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T417 31021-31026 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T418 31166-31177 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T419 31219-31221 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T421 31235-31237 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T423 31426-31437 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T424 31491-31496 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T425 31655-31666 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T426 31671-31682 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T427 31687-31698 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T428 31704-31715 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T429 31748-31753 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T430 31855-31866 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T431 32059-32070 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T432 32076-32094 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T433 32100-32112 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T434 32117-32128 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T435 32134-32152 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T436 32185-32190 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T437 32380-32391 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T438 32412-32423 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T439 32525-32530 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T440 32621-32632 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T441 32651-32662 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T442 32812-32817 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T443 32915-32921 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T444 32967-32978 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T445 33005-33007 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T447 33019-33029 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T448 33093-33104 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T449 33158-33163 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T450 33302-33321 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T451 33302-33311 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T452 33312-33321 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T453 33325-33335 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T454 33339-33350 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T455 33393-33398 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T456 33644-33646 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T458 33659-33661 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T460 33834-33844 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T461 33921-33926 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T462 34029-34040 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T463 34067-34069 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T465 34081-34091 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T466 34155-34166 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T467 34220-34225 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T468 34337-34342 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T469 34343-34348 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T470 34516-34521 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T471 34597-34607 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T472 34608-34619 Chemical denotes ruxolitinib http://purl.obolibrary.org/obo/CHEBI_66919
T473 34637-34648 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T474 34842-34844 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T476 34966-34972 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T477 35013-35019 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T478 35203-35209 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T479 35472-35478 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T480 35802-35808 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T481 35984-35990 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T482 36086-36092 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T483 36176-36182 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T484 36269-36275 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T485 36306-36313 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T486 36325-36331 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T487 36408-36414 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T488 36509-36523 Chemical denotes carbon dioxide http://purl.obolibrary.org/obo/CHEBI_16526
T489 36509-36515 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T491 36599-36605 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T492 36865-36871 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T493 37594-37600 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T494 37648-37654 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T495 37695-37701 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T496 38504-38508 Chemical denotes PEEP http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683
T498 38541-38546 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T499 39152-39158 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T500 39448-39452 Chemical denotes PEEP http://purl.obolibrary.org/obo/CHEBI_53359|http://purl.obolibrary.org/obo/CHEBI_60683
T502 39481-39486 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T503 39537-39543 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T504 39998-40014 Chemical denotes antiviral agents http://purl.obolibrary.org/obo/CHEBI_22587
T505 40040-40056 Chemical denotes antiviral agents http://purl.obolibrary.org/obo/CHEBI_22587
T506 40172-40188 Chemical denotes antiviral agents http://purl.obolibrary.org/obo/CHEBI_22587
T507 40314-40323 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T508 40329-40347 Chemical denotes protease inhibitor http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T510 40338-40347 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T511 40421-40430 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T512 40622-40641 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T513 40622-40631 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T514 40632-40641 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T515 40740-40745 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T516 41732-41737 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T517 42007-42026 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T519 42016-42026 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T520 42035-42044 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T521 42253-42257 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T522 42274-42284 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T523 42296-42301 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T524 42311-42329 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T525 42507-42530 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T526 42525-42530 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T527 42554-42559 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T528 42635-42644 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T529 42645-42654 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T530 42699-42712 Chemical denotes triglycerides http://purl.obolibrary.org/obo/CHEBI_17855
T531 42735-42743 Chemical denotes glutamyl http://purl.obolibrary.org/obo/CHEBI_32483
T532 43122-43133 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T533 43134-43152 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T534 43539-43551 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T535 43597-43600 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T536 43620-43635 Chemical denotes LDL cholesterol http://purl.obolibrary.org/obo/CHEBI_47774
T537 43620-43623 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T538 43624-43635 Chemical denotes cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T539 43976-43987 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T540 44431-44436 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T541 44437-44442 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T542 44566-44573 Chemical denotes alanine http://purl.obolibrary.org/obo/CHEBI_16449
T543 44592-44595 Chemical denotes AST http://purl.obolibrary.org/obo/CHEBI_76649
T544 44597-44606 Chemical denotes aspartate http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314
T547 44661-44664 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T548 44666-44689 Chemical denotes low-density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39026
T549 44678-44689 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T550 45018-45028 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T551 45427-45431 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T552 45443-45453 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T553 45577-45588 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T554 45593-45602 Chemical denotes zanamivir http://purl.obolibrary.org/obo/CHEBI_50663
T555 45607-45631 Chemical denotes neuraminidase inhibitors http://purl.obolibrary.org/obo/CHEBI_52425
T556 45621-45631 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T557 45770-45781 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T558 45786-45795 Chemical denotes zanamivir http://purl.obolibrary.org/obo/CHEBI_50663
T559 45947-45958 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T560 46231-46247 Chemical denotes antiviral agents http://purl.obolibrary.org/obo/CHEBI_22587
T561 46327-46338 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T562 46357-46381 Chemical denotes RNA polymerase inhibitor http://purl.obolibrary.org/obo/CHEBI_37416
T563 46372-46381 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T564 46416-46426 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T565 46463-46472 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T566 46647-46658 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T567 46916-46927 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T568 46967-46977 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T569 47049-47060 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T570 47317-47326 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T571 47395-47405 Chemical denotes ivermectin http://purl.obolibrary.org/obo/CHEBI_6078
T572 47551-47556 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T573 47654-47673 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T575 47663-47673 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T576 47680-47689 Chemical denotes darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T577 47790-47800 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T578 48020-48031 Chemical denotes favipiravir http://purl.obolibrary.org/obo/CHEBI_134722
T579 48036-48046 Chemical denotes umifenovir http://purl.obolibrary.org/obo/CHEBI_134730
T580 48162-48173 Chemical denotes Oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T581 48177-48186 Chemical denotes zanamivir http://purl.obolibrary.org/obo/CHEBI_50663
T582 48290-48301 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T583 48302-48320 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T584 48361-48372 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T585 48469-48478 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T586 48533-48542 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T587 48553-48564 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T588 48770-48778 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T589 48948-48953 Chemical denotes alpha http://purl.obolibrary.org/obo/CHEBI_30216
T590 48968-48970 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T592 49025-49036 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T593 49373-49391 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T594 49417-49428 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T595 49498-49502 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T99101 49736-49747 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T35786 49751-49769 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T33236 50174-50185 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T38375 50186-50204 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T43255 50454-50472 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T22535 50588-50606 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T82824 50796-50814 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T55345 50829-50841 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T89458 51003-51021 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T85954 51099-51104 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T1869 51294-51312 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T12 51461-51466 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T81198 51522-51540 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T67445 51546-51558 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T82623 51656-51668 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T20948 51684-51702 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T15096 51898-51903 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T18 51972-51990 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T4278 52076-52080 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T90933 52597-52615 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T85881 52732-52737 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T42152 52895-52913 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T24996 53068-53079 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T28167 53790-53801 Chemical denotes antibiotics http://purl.obolibrary.org/obo/CHEBI_33281
T50263 54607-54618 Chemical denotes methicillin http://purl.obolibrary.org/obo/CHEBI_6827
T63638 54696-54701 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T12136 54867-54876 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T83928 54887-54899 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T2753 54961-54973 Chemical denotes azithromycin http://purl.obolibrary.org/obo/CHEBI_2955
T998 55108-55118 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T84200 55574-55587 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T38237 55929-55948 Chemical denotes antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_33281
T27580 56002-56012 Chemical denotes antibiotic http://purl.obolibrary.org/obo/CHEBI_33281
T49484 56157-56165 Chemical denotes steroids http://purl.obolibrary.org/obo/CHEBI_35341
T92965 56220-56235 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T10348 56562-56580 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888
T76382 56936-56950 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T83355 57210-57224 Chemical denotes hydrocortisone http://purl.obolibrary.org/obo/CHEBI_17650
T63290 57332-57346 Chemical denotes hydrocortisone http://purl.obolibrary.org/obo/CHEBI_17650
T34671 57347-57352 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T72854 57377-57382 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T88411 57480-57495 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T98872 57739-57754 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T54230 57935-57949 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T17441 58268-58281 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T90766 58328-58341 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T70095 58529-58542 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T42283 58543-58548 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T49874 58569-58574 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T47088 58584-58589 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T59830 58684-58689 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T57744 58794-58807 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T54060 58808-58813 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T69982 58830-58835 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T2436 58861-58876 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T79577 59083-59097 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T14063 59324-59338 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T69694 59488-59502 Chemical denotes hydrocortisone http://purl.obolibrary.org/obo/CHEBI_17650
T25050 59608-59622 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T70959 60219-60234 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T7997 60348-60362 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T21891 60531-60546 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T62412 60851-60866 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T11802 61139-61146 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T65 61211-61218 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T15169 61889-61891 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T52655 62071-62078 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T41669 62181-62192 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T61099 62428-62439 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T28602 62523-62534 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T88075 62733-62740 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T73 62888-62899 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T72663 63107-63109 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T84369 63369-63380 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T38193 63437-63439 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T71139 63598-63609 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T42677 63666-63671 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T26418 63715-63725 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T58620 63750-63767 Chemical denotes enzyme inhibitors http://purl.obolibrary.org/obo/CHEBI_23924
T9262 63757-63767 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T85377 64293-64304 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T73580 64392-64397 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T92027 64762-64767 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T54631 64775-64786 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T89792 65343-65360 Chemical denotes enzyme inhibitors http://purl.obolibrary.org/obo/CHEBI_23924
T91905 65350-65360 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T11348 65852-65861 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T12438 66134-66143 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T94861 66542-66546 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T14598 66906-66916 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T18588 67107-67117 Chemical denotes antivirals http://purl.obolibrary.org/obo/CHEBI_22587
T87596 67222-67233 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T51549 67234-67252 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T54232 67257-67272 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T33985 67440-67445 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T99 67640-67658 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T38634 67819-67826 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T95699 68030-68037 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T17049 68290-68296 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T3796 68572-68581 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T49322 68728-68739 Chemical denotes oseltamivir http://purl.obolibrary.org/obo/CHEBI_7798
T90742 69159-69177 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T28849 69391-69409 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T57203 69715-69720 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T40359 69893-69904 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T32607 69905-69923 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T12702 70291-70298 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T60327 70368-70375 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T70825 70454-70465 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T55266 70466-70484 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T80885 70924-70934 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T73747 71180-71195 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T40348 71378-71385 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T52269 71469-71483 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T14062 72825-72830 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T26421 72841-72846 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T69721 72949-72954 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T38758 73230-73235 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T7632 73694-73699 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T22983 74067-74072 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T82876 74272-74277 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T125 74343-74348 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T27070 74349-74358 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T16804 74363-74386 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T98752 74381-74386 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 9246-9258 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T2 11181-11196 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T3 17600-17612 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T4 19977-19989 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T5 22854-22864 http://purl.obolibrary.org/obo/GO_0046903 denotes secretions
T6 25350-25365 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T7 26027-26038 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T8 26027-26038 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T9 26027-26038 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T10 26027-26038 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T11 26062-26075 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T12 33517-33529 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T13 39027-39035 http://purl.obolibrary.org/obo/GO_0015297 denotes exchange
T14 46447-46462 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T15 48731-48762 http://purl.obolibrary.org/obo/GO_0043687 denotes posttranslational modifications
T16 48932-48940 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T17 48932-48940 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T18 48932-48940 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T19 48932-48940 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T20 57034-57050 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T21 57647-57655 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T22 57647-57655 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T23 57647-57655 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T24 57647-57655 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T25 57787-57799 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T26 57800-57811 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T27 58053-58065 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T28 59756-59772 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T29 60623-60635 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T30 63969-63984 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T31 65454-65469 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-207 Sentence denotes Balancing evidence and frontline experience in the early phases of the COVID-19 pandemic: current position of the Italian Society of Anti-infective Therapy (SITA) and the Italian Society of Pulmonology (SIP)
T2 209-217 Sentence denotes Abstract
T3 218-228 Sentence denotes Background
T4 229-425 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which has rapidly become epidemic in Italy and other European countries.
T5 426-534 Sentence denotes The disease spectrum ranges from asymptomatic/mildly symptomatic presentations to acute respiratory failure.
T6 535-731 Sentence denotes At the present time the absolute number of severe cases requiring ventilator support is reaching or even surpassing the intensive care unit bed capacity in the most affected regions and countries.
T7 733-743 Sentence denotes Objectives
T8 744-947 Sentence denotes To narratively summarize the available literature on the management of COVID-19 in order to combine current evidence and frontline opinions and to provide balanced answers to pressing clinical questions.
T9 949-956 Sentence denotes Sources
T10 957-1020 Sentence denotes Inductive PubMed search for publications relevant to the topic.
T11 1022-1029 Sentence denotes Content
T12 1030-1223 Sentence denotes The available literature and the authors' frontline-based opinion are summarized in brief narrative answers to selected clinical questions, with a conclusive statement provided for each answer.
T13 1225-1237 Sentence denotes Implications
T14 1238-1350 Sentence denotes Many off-label antiviral and anti-inflammatory drugs are currently being administered to patients with COVID-19.
T15 1351-1623 Sentence denotes Physicians must be aware that, as they are not supported by high-level evidence, these treatments may often be ethically justifiable only in those worsening patients unlikely to improve only with supportive care, and who cannot be enrolled onto randomized clinical trials.
T16 1624-1809 Sentence denotes Access to well-designed randomized controlled trials should be expanded as much as possible because it is the most secure way to change for the better our approach to COVID-19 patients.
T17 1811-1823 Sentence denotes Introduction
T18 1824-2036 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19), which has rapidly become epidemic in Italy and other European countries [[1], [2], [3]].
T19 2037-2332 Sentence denotes The disease spectrum ranges from asymptomatic/mildly symptomatic presentations to acute respiratory failure, with the true proportion of severe cases still remaining partly unclear as a result of an incomplete denominator and a possible lack of adjustment for relevant confounding factors [4,5].
T20 2333-2647 Sentence denotes Nonetheless, of particular clinical concern at the present time is not the relative frequency of severe cases in patients requiring ventilation support, but rather their absolute number, which is reaching or even surpassing the intensive care unit (ICU) bed capacity in the most affected regions and countries [6].
T21 2648-3000 Sentence denotes From this perspective, in addition to the important prevention and restrictive measures implemented for reducing transmission [7], it remains crucial to optimize the therapeutic management of symptomatic patients requiring noninvasive oxygen therapy in order both to improve the absolute cure rates and to reduce and prevent the need for ICU admission.
T22 3001-3296 Sentence denotes However, the lack of high-level evidence, inherent to the novelty and rapid spread of COVID-19, has led to the adoption of heterogeneous approaches worldwide, often without a clear distinction between the relative weight of available evidence and expert opinion in informing therapeutic choices.
T23 3297-3577 Sentence denotes In this narrative review, we sought to summarize the available evidence on important therapeutic questions we are continuously facing as clinicians caring for COVID-19 patients in Italy, trying to find a balance between current evidence, frontline experiences and expert opinions.
T24 3579-3586 Sentence denotes Methods
T25 3587-3813 Sentence denotes Members of a panel of 17 experts from the Italian Society of Anti-infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) were selected; they developed a list of 8 practical therapeutic questions to be addressed.
T26 3814-4113 Sentence denotes The members of the panel (which included infectious diseases specialists and pneumonologists) were divided into small groups and asked to summarize the available literature and their frontline-based opinion in brief (500 words maximum) narrative answers, plus a conclusive statement for each answer.
T27 4114-4234 Sentence denotes All the answers and statements were ultimately reviewed and discussed by the entire panel until a consensus was reached.
T28 4235-4315 Sentence denotes A brief summary of questions and conclusive statements is available in Table 1 .
T29 4316-4491 Sentence denotes Table 2 summarizes available or ongoing randomized controlled trial (RCT) information for off-label/compassionate-use drugs mostly used for the treatment of COVID-19 patients.
T30 4492-4722 Sentence denotes Of note, we focused on pneumologic and anti-infective/anti-inflammatory treatments; the discussion of the therapeutic approach to COVID-19–related cardiovascular/coagulative disorders is outside the scope of this narrative review.
T31 4723-4766 Sentence denotes Table 1 Summary of questions and statements
T32 4767-4785 Sentence denotes Question Statement
T33 4786-4797 Sentence denotes Question 1.
T34 4798-4897 Sentence denotes How to use at best oxygen therapy and noninvasive mechanical ventilation for preventing intubation?
T35 4898-5092 Sentence denotes Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo2 lower than 90% and it should be aimed at reaching values not higher than 96%.
T36 5093-5397 Sentence denotes Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion).
T37 5398-5480 Sentence denotes However, no clear indications/criteria can be provided pending further experience.
T38 5481-5716 Sentence denotes Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be carefully monitored for worsening respiratory function for rapidly prompting tracheal intubation and mechanical ventilation.
T39 5717-5728 Sentence denotes Question 2.
T40 5729-5769 Sentence denotes Should antiviral agents be administered?
T41 5770-5900 Sentence denotes At the present time, evidence from the first published RCT does not support off-label treatment with LPV/RTV in COVID-19 patients.
T42 5901-6045 Sentence denotes This result should also discourage the use of other protease inhibitors (e.g. darunavir), at least until results of dedicated RCT are available.
T43 6046-6268 Sentence denotes Although promising in preclinical studies, remdesivir should be currently provided to COVID-19 patients only within RCT (preferentially) or compassionate-use/expanded-access programmes, owing to its investigational nature.
T44 6269-6453 Sentence denotes Pending high-level supporting evidence, favipiravir and umifenovir should not be provided an outside RCT, at least in those countries where they are not approved for other indications.
T45 6454-6561 Sentence denotes Oseltamivir or zanamivir should be provided only in the presence of suspected/proven concomitant influenza.
T46 6562-6573 Sentence denotes Question 3.
T47 6574-6628 Sentence denotes Should chloroquine/hydroxychloroquine be administered?
T48 6629-6878 Sentence denotes Pending results of RCT, the use of hydroxychloroquine may be considered for treating worsening patients with COVID-19 only if no important drug interactions can be anticipated and with close monitoring of hepatic, renal function and QT prolongation.
T49 6879-7088 Sentence denotes This is based on its activity in vitro against SARS-CoV-2 (although weak) and on the availability of low-level clinical evidence of anticipation of virus clearance from a small controlled, nonrandomized study.
T50 7089-7261 Sentence denotes However, it should also be kept in mind that the study was highly susceptible to bias and there are still no data regarding hard clinical endpoints such as crude mortality.
T51 7262-7386 Sentence denotes For these reasons, hydroxychloroquine should be preferentially administered within the framework of investigational studies.
T52 7387-7496 Sentence denotes When this is unfeasible, off-label use may be considered according to local protocols and consent procedures.
T53 7497-7693 Sentence denotes In view of the absence of evidence, we are currently unable to support the use of hydroxychloroquine in asymptomatic or mildly symptomatic nonhospitalized patients outside investigational studies.
T54 7694-7731 Sentence denotes The same applies to prophylactic use.
T55 7732-7743 Sentence denotes Question 4.
T56 7744-7779 Sentence denotes Should antibiotics be administered?
T57 7780-7962 Sentence denotes In our opinion, it might be prudent to consider empiric antibiotic treatment in critically ill patients with pneumonia due to COVID-19 in whom bacterial infection cannot be excluded.
T58 7963-8200 Sentence denotes This suggestion is based on the fact that bacterial coinfection (a) is common in patients with viral pneumonia and (b) can be associated with a substantial risk of delaying appropriate treatment, thereby potentially increasing mortality.
T59 8201-8448 Sentence denotes Because of the limited available data on both the microbiologic epidemiology (and the prevalence of antimicrobial resistance) of bacterial superinfections in COVID-19 patients, it is difficult to provide specific pathogen-oriented recommendations.
T60 8449-8863 Sentence denotes Therefore, pending further studies, we suggest to empirically treat COVID-19 patients according to their clinical syndrome (e.g. community-acquired pneumonia, hospital-acquired pneumonia), choosing the best antimicrobial agent or agents on the basis of local guidelines and local antibiotic susceptibility patterns, with early de-escalation or discontinuation according to microbiology results, whenever available.
T61 8864-8875 Sentence denotes Question 5.
T62 8876-8908 Sentence denotes Should steroids be administered?
T63 8909-9062 Sentence denotes So far, no definitive efficacy or effectiveness data are available on the benefit of corticosteroid administration in patients with SARS-CoV-2 infection.
T64 9063-9206 Sentence denotes As the WHO underlines, there is an important need for efficacy data from RCT for supporting corticosteroid therapy in patients with SARS-Cov-2.
T65 9207-9653 Sentence denotes However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for rapidly progressive pneumonia and clinical deterioration in COVID-19 patients, we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission).
T66 9654-9886 Sentence denotes Yet in the absence of convincing evidence, the following cannot currently be supported: (1) steroid administration stratified according to inflammatory markers; and (b) steroid administration in non–critically ill COVID-19 patients.
T67 9887-9898 Sentence denotes Question 6.
T68 9899-9980 Sentence denotes Should other immunosuppressive and/or immunomodulatory therapies be administered?
T69 9981-10135 Sentence denotes Owing to the lack of high-level evidence, administration of tocilizumab to patients with COVID-19 should preferentially occur within the framework of RCT.
T70 10136-10462 Sentence denotes Off-label use according to local protocols and consent procedures may be considered only in those COVID-19 patients excluded from RCT (or hospitalized where RCT are not available or still to be implemented) and who are worsening while receiving standard supportive care (in the absence of concomitant/superimposed infections).
T71 10463-10932 Sentence denotes In our opinion, this could be a reasonable off-label use of tocilizumab in these early phases of the COVID-19 pandemic, although patients and physicians should be aware that currently there is only a non–peer-reviewed, noncomparative, observational experience (very low evidence from an unreviewed cases series) and that it only supports a potential favourable effect on inflammatory signs and symptoms, while there is no information on any possible effect on survival.
T72 10933-11138 Sentence denotes In the absence of clinical studies, we suggest to preferentially administer also other immunosuppressive and/or immunomodulatory therapies (e.g. anakinra, Janus kinase family enzyme inhibitors) within RCT.
T73 11139-11457 Sentence denotes This also applies to modifications of the immune response through high-dose intravenous immunoglobulins or plasma from convalescent patients, which, although promising in small case series, both deserve dedicated RCT investigation to clearly understand their role in impacting COVID-19 outcomes and their tolerability.
T74 11458-11469 Sentence denotes Question 7.
T75 11470-11521 Sentence denotes What is the optimal timing of treatment initiation?
T76 11522-11817 Sentence denotes Supportive therapy (symptomatic therapy, rehydration and oxygen supplementation, if necessary), should be initiated as soon as the patient manifests respiratory or systemic symptoms, including severe asthenia, high fever, persistent cough and/or clinical or radiologic signs of lung involvement.
T77 11818-12088 Sentence denotes Pending further evidence, in our opinion, antiviral treatments should not be provided to patients with SARS-CoV-2 infection outside RCT or compassionate-use programmes (with the exception of early oseltamivir initiation in patients with suspected concomitant influenza).
T78 12089-12360 Sentence denotes Corticosteroids should be provided early in well-defined categories of patients (patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections), while their role in other COVID-19 patients still remains uncertain.
T79 12361-12747 Sentence denotes Although based on low-level evidence and pending RCT results, in our opinion, early hydroxychloroquine administration may be considered in COVID-19 patients manifesting moderate to severe symptoms, whereas further data are needed to better delineate the true balance between possible favourable effects and toxicity of hydroxychloroquine in mildly symptomatic and asymptomatic patients.
T80 12748-12759 Sentence denotes Question 8.
T81 12760-12799 Sentence denotes What is the optimal treatment duration?
T82 12800-13099 Sentence denotes Chloroquine/hydroxychloroquine treatment should be continued for at least 5 days, and possibly up to 20 days, according to some expert opinions, although it should be noted that data regarding the relative safety of different lengths of administration in COVID-19 patients are currently unavailable.
T83 13100-13227 Sentence denotes Early discontinuation should be considered in the presence of adverse effects (e.g. QT prolongation or hepatic/renal toxicity).
T84 13228-13505 Sentence denotes If the administration of remdesivir is approved within compassionate-use/expanded-access programmes, treatment duration should follow compassionate or expanded access protocols (e.g. up to 10 days according to the most recent compassionate protocol at the time of this review).
T85 13506-13623 Sentence denotes If corticosteroids are provided, we suggest a total treatment duration of 7–10 days, with progressive dose reduction.
T86 13624-13894 Sentence denotes If the patient's condition deteriorates with worsening lung physiology after withdrawal of steroid treatment in the absence of bacterial or fungal superinfection, a second course of corticosteroid treatment may be considered, followed by slow tapering after improvement.
T87 13895-14270 Sentence denotes ARDS, acute respiratory distress syndrome; COVID-19, coronavirus disease 2019; CPAP, continuous positive airway pressure; HFNC, high-flow nasal cannula; ICU, intensive care unit; LPV/RTV, lopinavir/ritonavir; PEEP, positive end expiratory pressure; RCT, randomized controlled trial; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; WHO, World Health Organization.
T88 14271-14446 Sentence denotes Table 2 Available and ongoing RCT on anti-infective and anti-inflammatory drugs most provided as off-label/compassionate treatments in the first phase of the COVID-19 pandemic
T89 14447-14598 Sentence denotes Drug Class/mechanism Published RCT Ongoing RCT for treatment/prevention of COVID-19 (recruiting or not yet recruiting) registered at ClinicalTrials.gov
T90 14599-14665 Sentence denotes Lopinavir/ritonavir Lopinavir is an HIV type 1 protease inhibitor.
T91 14666-14858 Sentence denotes Ritonavir is a CYP3A4 inhibitor that boosts lopinavir concentrations • Open-label RCT comparing lopinavir/ritonavir (99 patients) vs. standard of care (100) in patients with COVID-19 in China.
T92 14859-14936 Sentence denotes Lopinavir/ritonavir was administered at the dosage of 400/100 mg for 14 days.
T93 14937-15016 Sentence denotes The primary time-to-event endpoint was clinical improvement from randomization.
T94 15017-15405 Sentence denotes In the primary study population (ITT), no statistically significant differences were observed with regard to the primary endpoint of clinical improvement (HR 1.24 with standard of care as reference, 95% CI 0.90 to 1.72) and the secondary endpoint of 28-day mortality (19.2% vs. 25.0% in investigational and comparator arms, respectively; percentage difference −5.8%, 95% CI −17.3 to 5.7).
T95 15406-15559 Sentence denotes In the mITT population, lopinavir/ritonavir led to a median time to clinical improvement that was shorter by 1 day than that observed with standard care.
T96 15560-15732 Sentence denotes Median time between symptoms onset and randomization was 13 days (IQR 11–16) [22] • Comparison of lopinavir/ritonavir vs. hydroxychloroquine in patients with mild COVID-19.
T97 15733-15774 Sentence denotes Open-label RCT (NCT04307693, recruiting).
T98 15775-15834 Sentence denotes Primary endpoint: virus load at day 3, 5, 7, 10, 14 and 18.
T99 15835-15938 Sentence denotes • Comparison of ASC09/ritonavir vs. lopinavir/ritonavir in patients with confirmed COVID-19 pneumoniae.
T100 15939-15988 Sentence denotes Open-label RCT (NCT04261907, not yet recruiting).
T101 15989-16158 Sentence denotes Primary endpoint: adverse outcome at day 14 (composite of Spo 2 ≤ 93% without oxygen supplementation, PaO2/FiO2 ≤ 300 mm Hg or respiratory rate ≥ 30 breaths per minute).
T102 16159-16261 Sentence denotes • Comparison of lopinavir/ritonavir vs. lopinavir/ritonavir plus umifenovir in patients with COVID-19.
T103 16262-16303 Sentence denotes Open-label RCT (NCT04252885, recruiting).
T104 16304-16380 Sentence denotes Primary endpoint: rate of virus inhibition at day 0, 2, 4, 7, 10, 14 and 21.
T105 16381-16506 Sentence denotes • Comparison of lopinavir/ritonavir vs. lopinavir/ritonavir plus ribavirin plus interferon beta 1b in patients with COVID-19.
T106 16507-16548 Sentence denotes Open-label RCT (NCT04276688, recruiting).
T107 16549-16631 Sentence denotes Primary endpoint: time to negative nasopharyngeal swab RT-PCR (follow-up 30 days).
T108 16632-16775 Sentence denotes • Comparison of only supportive treatment vs. lopinavir/ritonavir vs. oseltamivir vs. umifenovir in patients with confirmed COVID-19 pneumonia.
T109 16776-16817 Sentence denotes Open-label RCT (NCT04255017, recruiting).
T110 16818-17093 Sentence denotes Primary endpoints: (a) rate of disease remission (mild disease: fever, cough and other symptoms relieved with improved lung CT; severe disease: fever, cough and other symptoms relieved with improved lung CT, Spo 2 > 93% or Pao 2/Fio 2 > 300 mm Hg); (b) time to lung recovery.
T111 17094-17206 Sentence denotes • Comparison of chemoprophylaxis with lopinavir/ritonavir vs. placebo in healthcare workers exposed to COVID-19.
T112 17207-17258 Sentence denotes Double-blind RCT (NCT04328285, not yet recruiting).
T113 17259-17353 Sentence denotes Primary endpoint: occurrence of a symptomatic or asymptomatic COVID-19 (follow-up 2.5 months).
T114 17354-17470 Sentence denotes • Comparison of carrimycin vs. lopinavir/ritonavir or umifenovir or chloroquine in patients with COVID-19 pneumonia.
T115 17471-17520 Sentence denotes Open-label RCT (NCT04286503, not yet recruiting).
T116 17521-17703 Sentence denotes Primary endpoints: (a) fever to normal time (follow-up 30 days); (b) pulmonary inflammation resolution time (follow-up 30 days); (c) negative conversion of throat swab RT-PCR at EOT.
T117 17704-17886 Sentence denotes • Comparison of lopinavir/ritonavir vs. lopinavir/ritonavir plus xiyanping (injectable component derived from a plant used in traditional Chinese medicine) in patients with COVID-19.
T118 17887-17936 Sentence denotes Open-label RCT (NCT04295551, not yet recruiting).
T119 17937-17998 Sentence denotes Primary endpoint: clinical recovery time (follow-up 28 days).
T120 17999-18168 Sentence denotes • Comparison of lopinavir/ritonavir plus inhaled interferon alfa vs. lopinavir/ritonavir plus inhaled interferon alfa plus xiyanping injection in patients with COVID-19.
T121 18169-18218 Sentence denotes Open-label RCT (NCT04275388, not yet recruiting).
T122 18219-18280 Sentence denotes Primary endpoint: clinical recovery time (follow-up 14 days).
T123 18281-18460 Sentence denotes • Comparison of lopinavir/ritonavir plus inhaled interferon alfa vs. lopinavir/ritonavir plus inhaled interferon alfa plus traditional Chinese medicines in patients with COVID-19.
T124 18461-18502 Sentence denotes Open-label RCT (NCT04251871, recruiting).
T125 18503-18580 Sentence denotes Primary endpoint: time to complete remission of symptoms (follow-up 28 days).
T126 18581-18796 Sentence denotes • Comparison of lopinavir/ritonavir plus hydroxychloroquine vs. lopinavir/ritonavir plus hydroxychloroquine plus levamisole pill plus budesonide plus formoterol inhaler in patients with nonsevere COVID-19 pneumonia.
T127 18797-18850 Sentence denotes Partly blinded RCT (NCT04331470, not yet recruiting).
T128 18851-18932 Sentence denotes Primary endpoint: (a) clear CT scan at 3–7 days; (b) negative RT-PCR at 3–7 days.
T129 18933-19044 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. losartan vs. placebos in patients with COVID-19.
T130 19045-19106 Sentence denotes Double-blind, adaptive RCT (NCT04328012, not yet recruiting).
T131 19107-19183 Sentence denotes Primary endpoint: NIAID COVID-19 ordinal severity scale (follow-up 60 days).
T132 19184-19353 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta 1a vs. remdesivir vs. standard of care in patients with COVID-19.
T133 19354-19407 Sentence denotes Double-blind, adaptive RCT (NCT04315948, recruiting).
T134 19408-19479 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 15.
T135 19480-19779 Sentence denotes • Comparison of lopinavir/ritonavir or umifenovir or chloroquine or hydroxychloroquine or oseltamivir (with or without azithromycin) vs. natural honey plus lopinavir/ritonavir or umifenovir or chloroquine or hydroxychloroquine or oseltamivir (with or without azithromycin) in patients with COVID-19.
T136 19780-19831 Sentence denotes Single-blind RCT (NCT04323345, not yet recruiting).
T137 19832-20025 Sentence denotes Primary endpoints: (a) positive to negative swabs at day 14; (b) fever to normal temperature in days (follow-up 14 days); (c) resolution of lung inflammation in CT or X-ray (follow-up 30 days).
T138 20026-20163 Sentence denotes • Comparison of colchicine (with or without lopinavir/ritonavir) vs. local standard of care in patients with moderate to severe COVID-19.
T139 20164-20213 Sentence denotes Open-label RCT (NCT04328480, not yet recruiting).
T140 20214-20272 Sentence denotes Primary endpoint: all-cause mortality (follow-up 30 days).
T141 20273-20677 Sentence denotes • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19.
T142 20678-20727 Sentence denotes Open-label RCT (NCT04303299, not yet recruiting).
T143 20728-20795 Sentence denotes Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks).
T144 20796-20826 Sentence denotes Remdesivir Adenosine analogue.
T145 20827-20992 Sentence denotes It binds to RNA-dependent RNA polymerase and acts as an RNA-chain terminator • Not available • Comparison of remdesivir vs. placebo in patients with severe COVID-19.
T146 20993-21036 Sentence denotes Double-blind RCT (NCT04257656, recruiting).
T147 21037-21126 Sentence denotes Primary endpoint: clinical status, assessed by an ordinal scale at days 7, 14, 21 and 28.
T148 21127-21209 Sentence denotes • Comparison of remdesivir vs. placebo in patients with mild to moderate COVID-19.
T149 21210-21253 Sentence denotes Double-blind RCT (NCT04252664, recruiting).
T150 21254-21327 Sentence denotes Primary endpoint: time to clinical recovery in hours (follow-up 28 days).
T151 21328-21415 Sentence denotes • Comparison of remdesivir vs. local standard of care in patients with severe COVID-19.
T152 21416-21457 Sentence denotes Open-label RCT (NCT04252664, recruiting).
T153 21458-21565 Sentence denotes Primary endpoint: composite of fever normalization and oxygen saturation normalization (follow-up 14 days).
T154 21566-21655 Sentence denotes • Comparison of remdesivir vs. local standard of care in patients with moderate COVID-19.
T155 21656-21697 Sentence denotes Open-label RCT (NCT04292730, recruiting).
T156 21698-21744 Sentence denotes Primary endpoint: discharged status at day 14.
T157 21745-21810 Sentence denotes • Comparison of remdesivir vs. placebo in patients with COVID-19.
T158 21811-21854 Sentence denotes Double-blind RCT (NCT04280705, recruiting).
T159 21855-21926 Sentence denotes Primary endpoint: severity rating on a 8-point ordinal scale at day 15.
T160 21927-22042 Sentence denotes • Comparison of remdesivir vs. hydroxychloroquine vs. remdesivir plus hydroxychloroquine in patients with COVID-19.
T161 22043-22101 Sentence denotes Open-label adaptive RCT (NCT04321616, not yet recruiting).
T162 22102-22172 Sentence denotes Primary endpoint: all-cause in-hospital mortality (follow-up 3 weeks).
T163 22173-22342 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta 1a vs. remdesivir vs. standard of care in patients with COVID-19.
T164 22343-22396 Sentence denotes Double-blind, adaptive RCT (NCT04315948, recruiting).
T165 22397-22468 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 15.
T166 22469-22536 Sentence denotes Darunavir/cobicistat Darunavir is an HIV type 1 protease inhibitor.
T167 22537-22717 Sentence denotes Cobicistat is a CYP3A4 inhibitor that boosts darunavir concentrations • Not available • Comparison of darunavir/cobicistat vs. standard of care in patients with COVID-19 pneumonia.
T168 22718-22759 Sentence denotes Open-label RCT (NCT04252274, recruiting).
T169 22760-22874 Sentence denotes Primary endpoint: virologic clearance rate of throat swabs, sputum or lower respiratory tract secretions at day 7.
T170 22875-23181 Sentence denotes Favipiravir Anti-influenza RNA-dependent RNA polymerase inhibitor • In a recent RCT published on a preprint server and comparing 120 COVID-19 patients treated with favipiravir vs. 120 COVID-19 patients receiving umifenovir, higher rates of clinical recovery were observed in patients receiving favipiravir.
T171 23182-23357 Sentence denotes The manuscript is publicly available but still to be peer reviewed [30] • Comparison of favipiravir vs. tocilizumab vs. favipiravir plus tocilizumab in patients with COVID-19.
T172 23358-23399 Sentence denotes Open-label RCT (NCT04310228, recruiting).
T173 23400-23453 Sentence denotes Primary endpoint: clinical cure (follow-up 3 months).
T174 23454-23858 Sentence denotes • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19.
T175 23859-23908 Sentence denotes Open-label RCT (NCT04303299, not yet recruiting).
T176 23909-23976 Sentence denotes Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks).
T177 23977-24085 Sentence denotes • Comparison of hydroxychloroquine plus darunavir/cobicistat vs. standard of care in patients with COVID-19.
T178 24086-24127 Sentence denotes Open-label RCT (NCT04304053, recruiting).
T179 24128-24245 Sentence denotes Primary endpoint: incidence of secondary cases among contacts of a case and contacts of contacts (follow-up 14 days).
T180 24246-24345 Sentence denotes • Comparison of chloroquine plus favipiravir vs. favipiravir vs. placebo in patients with COVID-19.
T181 24346-24389 Sentence denotes Double-blind RCT (NCT04319900, recruiting).
T182 24390-24561 Sentence denotes Primary endpoints: (a) time to improvement/recovery and frequency of improvement/recovery (follow-up 10 days); (b) time to negative swab/sputum RT-PCR (follow-up 10 days).
T183 24562-24637 Sentence denotes • Comparison of favipiravir vs. standard of care in patients with COVID-19.
T184 24638-24687 Sentence denotes Open-label RCT (NCT04333589, not yet recruiting).
T185 24688-24800 Sentence denotes Primary endpoint: viral nucleic acid test negative conversion rate in nasopharyngeal swabs (follow-up 5 months).
T186 24801-25205 Sentence denotes • Comparison of oseltamivir plus chloroquine vs. oseltamivir plus lopinavir/ritonavir in patients with mild COVID-19 and of lopinavir/ritonavir plus oseltamivir vs. darunavir/ritonavir plus oseltamivir vs. favipiravir plus lopinavir/ritonavir vs. darunavir/ritonavir plus oseltamivir plus chloroquine vs. darunavir/ritonavir plus favipiravir plus oseltamivir in patients with moderate to severe COVID-19.
T187 25206-25255 Sentence denotes Open-label RCT (NCT04303299, not yet recruiting).
T188 25256-25323 Sentence denotes Primary endpoint: SARS-CoV-2 eradication time (follow-up 24 weeks).
T189 25324-25616 Sentence denotes Umifenovir Anti-influenza membrane fusion inhibitor • In a recent RCT published on a preprint server and comparing 120 COVID-19 patients treated with favipiravir vs. 120 COVID-19 patients receiving umifenovir, higher rates of clinical recovery were observed in patients receiving favipiravir.
T190 25617-25773 Sentence denotes The manuscript is publicly available but still to be peer reviewed [30] • Comparison of umifenovir vs. standard of care in patients with COVID-19 pneumonia.
T191 25774-25823 Sentence denotes Open-label RCT (NCT04260594, not yet recruiting).
T192 25824-25892 Sentence denotes Primary endpoint: virus negative conversion rate (follow-up 7 days).
T193 25893-26272 Sentence denotes Chloroquine, hydroxychloroquine Some proposed mechanisms are the following: increase in the endosomal Ph necessary for the virus/host cell fusion; interference with the glycosylation of cell receptors; immunomodulatory activity • Not available • Comparison of different hydroxychloroquine dosages vs. placebo in three cohorts (outpatients, inpatients, healthcare workers a risk).
T194 26273-26397 Sentence denotes Double-blind RCT for outpatients and healthcare workers and open-label RCT for inpatients (NCT04329923, not yet recruiting).
T195 26398-26595 Sentence denotes Primary endpoints: (a) release from quarantine (outpatients, follow-up 14 days); (b) discharge (inpatients, follow-up 14 days); (c) development of COVID-19 (healthcare workers, follow-up 2 months).
T196 26596-26682 Sentence denotes • Comparison of hydroxychloroquine vs. ascorbic acid in contacts of COVID-19 patients.
T197 26683-26734 Sentence denotes Double-blind RCT (NCT04328961, not yet recruiting).
T198 26735-26803 Sentence denotes Primary endpoint: laboratory-confirmed COVID-19 (follow-up 14 days).
T199 26804-26940 Sentence denotes • Comparison of tocilizumab plus hydroxychloroquine plus azithromycin vs. tocilizumab plus hydroxychloroquine in patients with COVID-19.
T200 26941-26990 Sentence denotes Open-label RCT (NCT04332094, not yet recruiting).
T201 26991-27218 Sentence denotes Primary endpoints: (a) in-hospital mortality (follow-up 2 weeks); (b) need for mechanical ventilation in the ICU (follow-up 2 weeks).• Comparison of ciclesonide plus hydroxychloroquine vs. ciclesonide in patients with COVID-19.
T202 27219-27268 Sentence denotes Open-label RCT (NCT04330586, not yet recruiting).
T203 27269-27342 Sentence denotes Primary endpoint: SARS-CoV-2 eradication (based on virus load) at day 14.
T204 27343-27469 Sentence denotes • Comparison of hydroxychloroquine vs. placebo in patients with COVID-19 and under biological treatment and/or JAK inhibitors.
T205 27470-27521 Sentence denotes Double-blind RCT (NCT04330495, not yet recruiting).
T206 27522-27732 Sentence denotes Primary endpoints: (a) incidence rate of COVID-19 (follow-up 27 weeks); (b) prevalence of COVID-19 (follow-up 27 weeks); (c) case fatality rate (follow-up 27 weeks); (d) ICU admission rate (follow-up 27 weeks).
T207 27733-27841 Sentence denotes • Comparison of hydroxychloroquine vs. placebo for the prevention of COVID-19 in healthcare workers at risk.
T208 27842-27893 Sentence denotes Double-blind RCT (NCT04328467, not yet recruiting).
T209 27894-27956 Sentence denotes Primary endpoint: prevalence of COVID-19 (follow-up 12 weeks).
T210 27957-28069 Sentence denotes • Comparison of chemoprophylaxis with lopinavir/ritonavir vs. placebo in healthcare workers exposed to COVID-19.
T211 28070-28121 Sentence denotes Double-blind RCT (NCT04328285, not yet recruiting).
T212 28122-28139 Sentence denotes Primary endpoint:
T213 28140-28228 Sentence denotes Occurrence of a symptomatic or asymptomatic SARS-CoV-2 infection (follow-up 2.5 months).
T214 28229-28350 Sentence denotes • Comparison of hydroxychloroquine vs. placebo in symptomatic COVID-19 patients or exposed healthcare workers/households.
T215 28351-28394 Sentence denotes Double-blind RCT (NCT04308668, recruiting).
T216 28395-28542 Sentence denotes Primary endpoints: (a) incidence of symptomatic COVID-19 among asymptomatic participants; (b) severity rating on a 3-point ordinal scale at day 14.
T217 28543-28658 Sentence denotes • Comparison of remdesivir vs. hydroxychloroquine vs. remdesivir plus hydroxychloroquine in patients with COVID-19.
T218 28659-28717 Sentence denotes Open-label adaptive RCT (NCT04321616, not yet recruiting).
T219 28718-28788 Sentence denotes Primary endpoint: all-cause in-hospital mortality (follow-up 3 weeks).
T220 28789-28900 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. losartan vs. placebos in patients with COVID-19.
T221 28901-28962 Sentence denotes Double-blind, adaptive RCT (NCT04328012, not yet recruiting).
T222 28963-29039 Sentence denotes Primary endpoint: NIAID COVID-19 Ordinal Severity Scale (follow-up 60 days).
T223 29040-29198 Sentence denotes • Comparison of convalescent plasma plus hydroxychloroquine plus azithromycin vs. hydroxychloroquine plus azithromycin in hospitalized patients with COVID-19.
T224 29199-29248 Sentence denotes Open-label RCT (NCT04332835, not yet recruiting).
T225 29249-29428 Sentence denotes Primary endpoints: (a) change in virus load at days 0, 4, 7, 14 and 28; (b) change in IgM COVID-19 titers at days 0, 4, 7, 14 and 28; (c) change in IgG at days 0, 4, 7, 14 and 28.
T226 29429-29598 Sentence denotes • Comparison of lopinavir/ritonavir vs. hydroxychloroquine vs. lopinavir/ritonavir plus interferon beta-1a vs. remdesivir vs. standard of care in patients with COVID-19.
T227 29599-29652 Sentence denotes Double-blind, adaptive RCT (NCT04315948, recruiting).
T228 29653-29724 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 15.
T229 29725-30087 Sentence denotes Methylprednisolone A subgroup of patients with severe COVID-19 might develop a cytokine storm syndrome which causes rapidly progressive pneumonia, ARDS and clinical deterioration and corticosteroids administration may halt the dysregulated cytokine release • Not available • Comparison of methylprednisolone vs. standard of care in patients with severe COVID-19.
T230 30088-30129 Sentence denotes Open-label RCT (NCT04244591, recruiting).
T231 30130-30196 Sentence denotes Primary endpoint: lower Murray lung injury score at days 7 and 14.
T232 30197-30279 Sentence denotes • Comparison of methylprednisolone vs. standard of care in patients with COVID-19.
T233 30280-30321 Sentence denotes Open-label RCT (NCT04273321, recruiting).
T234 30322-30378 Sentence denotes Primary endpoint: treatment failure (follow-up 14 days).
T235 30379-30579 Sentence denotes • Comparison of inhaled alpha interferon plus methylprednisolone plus umifenovir vs. thalidomide plus inhaled alpha interferon plus methylprednisolone plus umifenovir in patients with severe COVID-19.
T236 30580-30631 Sentence denotes Double-blind RCT (NCT04273581, not yet recruiting).
T237 30632-30699 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 28 days).
T238 30700-30782 Sentence denotes • Comparison of different dosages of methylprednisolone in patients with COVID-19.
T239 30783-30824 Sentence denotes Open-label RCT (NCT04263402, recruiting).
T240 30825-30906 Sentence denotes Primary endpoints: (a) disease readmission at day 7; (b) critical stage at day 7.
T241 30907-31015 Sentence denotes • Comparison of siltuximab (anti–IL-6 monoclonal antibody) vs. methylprednisolone in patients with COVID-19.
T242 31016-31065 Sentence denotes Open-label RCT (NCT04329650, not yet recruiting).
T243 31066-31117 Sentence denotes Primary endpoint: ICU admission (follow-up 29 days)
T244 31118-31234 Sentence denotes Tocilizumab Humanized monoclonal IgG1 antibody, tocilizumab inhibits both membrane-bound and soluble IL-6 receptors.
T245 31235-31485 Sentence denotes IL-6, is one of the main drivers of immunologic response and symptoms in patients with dysregulated cytokine release that has been observed in severe COVID-19 • Not available • Comparison of tocilizumab vs. standard of care in patients with COVID-19.
T246 31486-31535 Sentence denotes Open-label RCT (NCT04331808, not yet recruiting).
T247 31536-31638 Sentence denotes Primary endpoint: WHO progression scale at day 7 and 14 (severity rating on a 10-point ordinal scale).
T248 31639-31742 Sentence denotes • Comparison of favipiravir vs. tocilizumab vs. favipiravir plus tocilizumab in patients with COVID-19.
T249 31743-31784 Sentence denotes Open-label RCT (NCT04310228, recruiting).
T250 31785-31838 Sentence denotes Primary endpoint: clinical cure (follow-up 3 months).
T251 31839-31918 Sentence denotes • Comparison of tocilizumab vs. placebo in hospitalized patients with COVID-19.
T252 31919-31970 Sentence denotes Double-blind RCT (NCT04320615, not yet recruiting).
T253 31971-32042 Sentence denotes Primary endpoint: severity rating on a 7-point ordinal scale at day 28.
T254 32043-32179 Sentence denotes • Comparison of tocilizumab plus hydroxychloroquine plus azithromycin vs. tocilizumab plus hydroxychloroquine in patients with COVID-19.
T255 32180-32229 Sentence denotes Open-label RCT (NCT04332094, not yet recruiting).
T256 32230-32363 Sentence denotes Primary endpoints: (a) in-hospital mortality (follow-up 2 weeks); (b) need for mechanical ventilation in the ICU (follow-up 2 weeks).
T257 32364-32519 Sentence denotes • Comparison of chloroquine analog (GNS651) vs. tocilizumab vs. nivolumab vs. standard of care in patients with advanced or metastatic cancer and COVID-19.
T258 32520-32569 Sentence denotes Open-label RCT (NCT04333914, not yet recruiting).
T259 32570-32587 Sentence denotes Primary endpoint:
T260 32588-32604 Sentence denotes 28-day survival.
T261 32605-32806 Sentence denotes • Comparison of tocilizumab intravenously vs. tocilizumab subcutaneously vs. sarilumab (anti-interleukin 6 receptor α monoclonal antibody) subcutaneously vs. standard of care in patients with COVID-19.
T262 32807-32856 Sentence denotes Open-label RCT (NCT04322773, not yet recruiting).
T263 32857-32950 Sentence denotes Primary endpoint: time to independence from supplementary oxygen therapy (follow-up 28 days).
T264 32951-33152 Sentence denotes • Comparison of tocilizumab vs. anakinra (recombinant IL-1 receptor antagonist) vs. siltuximab vs. anakinra plus siltuximab vs. anakinra plus tocilizumab vs. standard of care in patients with COVID-19.
T265 33153-33202 Sentence denotes Open-label RCT (NCT04330638, not yet recruiting).
T266 33203-33270 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 15 days).
T267 33271-33387 Sentence denotes • Comparison of carrimycin vs. lopinavir/ritonavir or umifenovir or chloroquine in patients with COVID-19 pneumonia.
T268 33388-33437 Sentence denotes Open-label RCT (NCT04286503, not yet recruiting).
T269 33438-33620 Sentence denotes Primary endpoints: (a) fever to normal time (follow-up 30 days); (b) pulmonary inflammation resolution time (follow-up 30 days); (c) negative conversion of throat swab RT-PCR at EOT.
T270 33621-33658 Sentence denotes Anakinra Antagonist of IL-1 receptor.
T271 33659-33915 Sentence denotes IL-1 is one of the main drivers of immunologic response and symptoms in patients with cytokine-release syndrome. • Not available • Comparison of anakinra vs. emapalumab (anti–interferon γ monoclonal antibody) vs. standard of care in patients with COVID-19.
T272 33916-33965 Sentence denotes Open-label RCT (NCT04324021, not yet recruiting).
T273 33966-34012 Sentence denotes Primary endpoint: treatment success at day 15.
T274 34013-34214 Sentence denotes • Comparison of tocilizumab vs. anakinra (recombinant IL-1 receptor antagonist) vs. siltuximab vs. anakinra plus siltuximab vs. anakinra plus tocilizumab vs. standard of care in patients with COVID-19.
T275 34215-34264 Sentence denotes Open-label RCT (NCT04330638, not yet recruiting).
T276 34265-34332 Sentence denotes Primary endpoint: time to clinical improvement (follow-up 15 days).
T277 34333-34466 Sentence denotes Off-label drugs mostly provided in Italy during the first phase of the COVID-19 pandemic according to the authors' direct experience.
T278 34467-34650 Sentence denotes Of note, there are also registered RCT for other drugs to be investigated in patients with COVID-19 (e.g. the Janus kinase family inhibitors ruxolitinib, baricitinib and tofacitinib).
T279 34651-35170 Sentence denotes ARDS = acute respiratory distress syndrome; CI, confidence interval; COVID-19, coronavirus disease 2019; CT, computed tomography; EOT, end of treatment; HR, hazard ratio; Ig, immunoglobulin; IL-1, interleukin 1; IQR, interquartile range; ITT, intent to treat; mITT, modified intent to treat; Pao2/Fio2, of arterial oxygen partial pressure to fractional inspired oxygen; RCT, randomized controlled trial; RT-PCR, real-time PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; WHO, World Health Organization.
T280 35172-35283 Sentence denotes Question 1. how to use at best oxygen therapy and noninvasive mechanical ventilation for preventing intubation?
T281 35284-35487 Sentence denotes In moderate to severe cases, COVID-19 usually presents as a lung disease (mostly in the form of bilateral interstitial pneumonia) causing hypoxic respiratory failure and requiring passive oxygen therapy.
T282 35488-35586 Sentence denotes The prevalence of hypoxic respiratory failure in patients with COVID-19 may be as high as 19% [8].
T283 35587-35789 Sentence denotes In observational studies conducted in China, 4% to 13% of COVID-19 patients received noninvasive positive pressure ventilation, and 2.3% to 12% required invasive mechanical ventilation [[8], [9], [10]].
T284 35790-36078 Sentence denotes In general, oxygen treatment should be provided to patients with shortness of breath or hypoxaemia, or those in shock, which is aimed at maintaining an appropriate level of peripheral capillary oxygen saturation (Spo 2), avoiding values of Spo 2 lower than 90% (92–95% in pregnant women).
T285 36079-36144 Sentence denotes During oxygen supplementation, Spo 2 should not surpass 96% [11].
T286 36145-36257 Sentence denotes An alternative to conventional oxygen supplementation is supplementation through high-flow nasal cannula (HFNC).
T287 36258-36359 Sentence denotes HFNC is an oxygen supply system that provides a mixture of air and oxygen with a known concentration.
T288 36360-36641 Sentence denotes HFNC provides high concentrations of humidified oxygen and low levels of positive end-expiratory pressure; it can also facilitate the elimination of carbon dioxide, thereby potentially reducing the need for intubation compared to standard oxygen supplementation [[12], [13], [14]].
T289 36642-36956 Sentence denotes However, it should also be considered that there are no standard evidence-based guidelines for the use of HFNC and that the experience in patients with COVID-19 is still limited (and without adjusted comparison to standard oxygen supplement) to provide universal recommendations, at least pending further data [9].
T290 36957-37339 Sentence denotes Other relevant things to be considered are: (a) HFNC should be used in settings with rapid availability of endotracheal intubation in the case of rapid deterioration [15]; and (b) the possible increased risk of contracting the infection for healthcare personnel as a result of aerosol generation should be appropriately managed (HFNC should be used in negative-pressure rooms) [16].
T291 37340-37802 Sentence denotes These two considerations also apply to continuous positive airway pressure (CPAP) with helmet (the most frequent system of noninvasive mechanical ventilation used in real life), which can be considered if the patient does not respond to standard or HFNC oxygen supplementation (i.e. if the ratio of arterial oxygen partial pressure to fractional inspired oxygen (Pao 2/Fio 2) has a decreasing trend) and there is no urgent indication for endotracheal intubation.
T292 37803-37952 Sentence denotes As for HFNC, also in the case of CPAP with helmet, close monitoring and short interval assessment for worsening of respiratory failure are mandatory.
T293 37953-38340 Sentence denotes In addition, it should be necessarily noted that although CPAP with helmet has become an established procedure for primary hypoxemic lung failure in the last few years, some experts do not support its use for COVID-19 [15], arguing that success rates in critically ill COVID-19 patients may be limited and there could be a risk of delayed intubation unfavourably influencing the outcome.
T294 38341-38679 Sentence denotes However, considering the atypical physiopathology of acute lung injury in patients with COVID-19 [17], gentle ventilation with a positive end expiratory pressure (PEEP) not higher than 10 to 12 cm of water may represent a reasonable approach for avoiding excessive damage during CPAP with helmet and possibly also the need for intubation.
T295 38680-38814 Sentence denotes Large studies, possibly RCT, are urgently needed to definitely clarify the precise role of CPAP with helmet in patients with COVID-19.
T296 38815-39115 Sentence denotes Finally, borrowing from what is already known and used in intensive care, pronation, although certainly more difficult to implement during noninvasive than invasive mechanical ventilation, may allow improved gas exchange and decreased respiratory distress, and may also promote lung recruitment [18].
T297 39117-39137 Sentence denotes Question 1 statement
T298 39138-39334 Sentence denotes Supplementary oxygen should be administered to patients with hypoxic respiratory failure for avoiding values of Spo 2 lower than 90%, and it should be aimed at reaching values not higher than 96%.
T299 39335-39639 Sentence denotes Although still without firm evidence, we currently support the use of CPAP helmet (with gentle ventilation and a PEEP of no more than 10–12 cm of water) if the patient does not respond to standard/HFNC oxygen supplementation and there is no urgent indication for endotracheal intubation (expert opinion).
T300 39640-39722 Sentence denotes However, no clear indications/criteria can be provided pending further experience.
T301 39723-39977 Sentence denotes Finally, it should be kept in mind that patients with COVID-19 can get worse in a few hours, so they should be closely monitored for worsening respiratory function so that tracheal intubation and mechanical ventilation can be quickly performed if needed.
T302 39979-40031 Sentence denotes Question 2. should antiviral agents be administered?
T303 40032-40313 Sentence denotes Several antiviral agents have demonstrated in vitro activity against SARS-CoV-2 or other coronaviruses, but currently there are no approved antiviral agents for coronavirus-related diseases, and there are still no favourable efficacy results from RCT available at the present time.
T304 40314-40462 Sentence denotes Lopinavir is a protease inhibitor used for the treatment of HIV patients, administered in combination with ritonavir to improve its serum half-life.
T305 40463-40764 Sentence denotes On the basis of its activity against SARS-CoV-1 and/or Middle East respiratory syndrome (MERS)-CoV observed in in vitro and animal studies [[19], [20], [21]], lopinavir/ritonavir (LPV/RTV) was compared to supportive care alone for the treatment of COVID-19 patients in an open-label RCT in China [22].
T306 40765-41013 Sentence denotes The primary time-to-event endpoint was clinical improvement from randomization (defined as a composite of discharge from the hospital or improvement of two points on a seven-category ordinal scale, ranging from no need of hospitalization to death).
T307 41014-41117 Sentence denotes Overall, 199 patients were enrolled (99 and 100 in the LPV/RTV and supportive care arms, respectively).
T308 41118-41315 Sentence denotes No differences were observed in the intent-to-treat population with regard to clinical improvement (hazard ratio 1.24 with standard of care as reference, 95% confidence interval (CI) 0.90 to 1.72).
T309 41316-41584 Sentence denotes In addition, no associations were observed with regard to 28-day mortality, although a smaller number of deaths were registered in the LPV/RTV arm (19.2% vs. 25.0% in investigational and comparator arms, respectively; percentage difference −5.8%, 95% CI −17.3 to 5.7).
T310 41585-42231 Sentence denotes Although some important considerations preclude a definite judgement on the possible efficacy of LPV/RTV (e.g. some major limitations are the open-label nature of the trial and the fact that LPV/RTV was initiated late with respect to the onset of symptoms; see question 7), especially in the case of early therapy initiation, the results of this RCT provide evidence currently discouraging the use of LPV/RTV (or of other protease inhibitors such as darunavir) in COVID-19 patients (also considering the potential side effects; Table 3 ), unless favourable results from other ongoing RCT in specific subgroups of patients are available (Table 2).
T311 42232-42446 Sentence denotes Furthermore, harmful drug interactions of antivirals with other drugs (such as hydroxychloroquine) cannot be excluded a priori because there are currently no large clinical data about the use of these combinations.
T312 42447-42614 Sentence denotes Table 3 Known adverse events of marketed anti-infective and anti-inflammatory drugs mostly provided as off-label treatments in the first phase of the COVID-19 pandemic
T313 42615-42634 Sentence denotes Drug Adverse events
T314 42635-42720 Sentence denotes Lopinavir/ritonavir • Hypercholesterolaemia and increased serum triglycerides (3–39%)
T315 42721-42764 Sentence denotes • Increased γ-glutamyl transferase (10–29%)
T316 42765-42816 Sentence denotes • Diarrhoea (7–28%; greater with once-daily dosing)
T317 42817-42850 Sentence denotes • Increased serum ALT (grade 3/4:
T318 42851-42857 Sentence denotes 1–11%)
T319 42858-42874 Sentence denotes • Nausea (5–16%)
T320 42875-42916 Sentence denotes • Upper respiratory tract infection (14%)
T321 42917-42941 Sentence denotes • Abdominal pain (1–11%)
T322 42942-42959 Sentence denotes • Vomiting (2–7%)
T323 42960-42974 Sentence denotes • Fatigue (8%)
T324 42975-43021 Sentence denotes • Increased serum amylase and/or lipase (3–8%)
T325 43022-43039 Sentence denotes • Headache (2–6%)
T326 43040-43057 Sentence denotes • Skin rash (≤5%)
T327 43058-43083 Sentence denotes • Neutropenia (grade 3/4:
T328 43084-43089 Sentence denotes 1–5%)
T329 43090-43104 Sentence denotes • Anxiety (4%)
T330 43105-43121 Sentence denotes • Insomnia (≤4%)
T331 43122-43192 Sentence denotes Chloroquine/hydroxychloroquine • Retinopathy (4% of treated patients)a
T332 43193-43444 Sentence denotes • Other adverse effects with unknown frequency included Stevens-Johnson syndrome, abdominal pain, diarrhoea, nausea, vomiting, agranulocytosis, leukopenia, thrombocytopenia, abnormal hepatic function tests, acute hepatic ailure, myopathy, bronchospasm
T333 43445-43551 Sentence denotes • Risk of prolonged QT interval, further increased when administered with fluoroquinolones or azithromycin
T334 43552-43607 Sentence denotes Tocilizumab • Increased serum ALT (≤36%) and AST (≤22%)
T335 43608-43643 Sentence denotes • Increased LDL cholesterol (9–10%)
T336 43644-43677 Sentence denotes • Injection site reaction (4–10%)
T337 43678-43701 Sentence denotes • Neutropenia (grade 3:
T338 43702-43729 Sentence denotes 2–7% of all adult patients)
T339 43730-43747 Sentence denotes • Headache (1–7%)
T340 43748-43769 Sentence denotes • Hypertension (1–6%)
T341 43770-43786 Sentence denotes • Dizziness (3%)
T342 43787-43809 Sentence denotes • Hypothyroidism (<2%)
T343 43810-43831 Sentence denotes • Abdominal pain (2%)
T344 43832-43868 Sentence denotes • Oral mucosa or gastric ulcers (2%)
T345 43869-44042 Sentence denotes • Infections due to Pneumocystis, Mycobacterium tuberculosis and varicella zoster have been reported after tocilizumab, but their prevalence has not been clearly established
T346 44043-44087 Sentence denotes Anakinra • Injection site reactionb (24–71%)
T347 44088-44201 Sentence denotes • Antibody development (up to 50% of the patients but no correlation of antibody development and adverse effects)
T348 44202-44234 Sentence denotes • Headache and vomiting (12–14%)
T349 44235-44256 Sentence denotes • Arthralgia (10–12%)
T350 44257-44273 Sentence denotes • Fever (10–12%)
T351 44274-44368 Sentence denotes • Haematologic disorder including eosinophilia, leukopenia and change in platelet count (2–9%)
T352 44369-44398 Sentence denotes • Nausea and diarrhoea (7–8%)
T353 44399-44426 Sentence denotes • Serious infectionc (2–3%)
T354 44427-44560 Sentence denotes Off-label drugs mostly provided in Italy during the first phase of the COVID-19 pandemic according to the authors' direct experience.
T355 44561-44690 Sentence denotes ALT, alanine aminotransferase; AST, aspartate aminotransferase; COVID-19, coronavirus disease 2019; LDL, low-density lipoprotein.
T356 44691-44831 Sentence denotes a Serum concentration dependent adverse effect; early changes are generally reversible but may progress despite discontinuation if advanced.
T357 44832-44900 Sentence denotes b Injection site reactions were considered serious in 2–3% of cases.
T358 44901-44984 Sentence denotes c Serious infections included cellulitis, pneumonia, and bone and joint infections.
T359 44985-45240 Sentence denotes Remdesivir is an investigational nucleotide analogue undergoing clinical development for Ebola and showing in vitro activity against coronaviruses (SARS-CoV-2, SARS-CoV-1 and MERS-CoV) and favourable effects in animal MERS models [[23], [24], [25], [26]].
T360 45241-45344 Sentence denotes Following these promising preclinical findings, RCT in COVID-19 patients have been initiated (Table 2).
T361 45345-45576 Sentence denotes However, pending their results, and considering the investigational nature of the drug, access to remdesivir outside RCT is currently provided only within strictly regulated and limited compassionate-use/expanded-access frameworks.
T362 45577-45736 Sentence denotes Oseltamivir and zanamivir are neuraminidase inhibitors used for treating influenza which are also being tested in RCT for treating COVID-19 patients (Table 2).
T363 45737-46046 Sentence denotes However, no apparent activity of oseltamivir and zanamivir has previously been observed against SARS-CoV-1 in vitro [27], and the fact that up to 76% of the first critically ill patients with COVID-19 received oseltamivir may also be related to the suspicion of infection (or coinfection) with influenza [28].
T364 46047-46224 Sentence denotes Overall, this information is currently insufficient for supporting the use of these agents in COVID-19 patients unless in the presence of suspected/proven concomitant influenza.
T365 46225-46478 Sentence denotes Other antiviral agents currently being investigated in RCT for the treatment of COVID-19 patients are favipiravir, an RNA-dependent RNA polymerase inhibitor with anti-influenza activity, and umifenovir, and anti-influenza membrane fusion inhibitor [29].
T366 46479-46841 Sentence denotes Even though these two agents attracted important media attention in the last few months, and even though there were some favourable preliminary results, especially for favipiravir, released as preprints, we advocate caution in using these agents outside investigational studies until completion of the standard peer-review processes of the first released trials.
T367 46842-47307 Sentence denotes For example, in a recent RCT comparing 120 COVID-19 patients treated with favipiravir versus 120 COVID-19 patients receiving umifenovir, higher rates of clinical recovery were observed in patients receiving favipiravir, but it is of note that the all-cause mortality was 0 in the entire study population, making it uncertain whether, if confirmed, these favourable results may be extrapolated to relevant survival endpoints in critically ill COVID-19 patients [30].
T368 47308-47448 Sentence denotes Finally, antiviral activity against SARS-CoV-2 in vitro has been recently reported for ivermectin, but clinical data are still lacking [31].
T369 47450-47470 Sentence denotes Question 2 statement
T370 47471-47601 Sentence denotes At the present time, evidence from the first published RCT does not support off-label treatment with LPV/RTV in COVID-19 patients.
T371 47602-47746 Sentence denotes This result should also discourage the use of other protease inhibitors (e.g. darunavir), at least until results of dedicated RCT are available.
T372 47747-47979 Sentence denotes Although promising in preclinical studies, remdesivir should be currently provided for treating COVID-19 patients only within RCT (preferentially) or compassionate-use/expanded-access programmes, owing to its investigational nature.
T373 47980-48161 Sentence denotes Pending high-level supporting evidence, favipiravir and umifenovir should not be provided outside RCT, at least in those countries where they are not approved for other indications.
T374 48162-48269 Sentence denotes Oseltamivir or zanamivir should be provided only in the presence of suspected/proven concomitant influenza.
T375 48271-48337 Sentence denotes Question 3. should chloroquine/hydroxychloroquine be administered?
T376 48338-48517 Sentence denotes The rationale of using chloroquine for treating COVID-19 patients is based on two potential and non–mutually exclusive mechanisms: antiviral activity and immunomodulatory effects.
T377 48518-48851 Sentence denotes With regard to antiviral activity, chloroquine has been shown to inhibit various viruses in cell cultures, including SARS-CoV-1 and SARS-CoV-2, possibly via pH-dependent inhibition of virus–endosome fusion and/or posttranslational modifications of CoV proteins, although other mechanisms may also contribute [[32], [33], [34], [35]].
T378 48852-49200 Sentence denotes With regard to the immunomodulatory effects, the attenuated production of tumor necrosis factor alpha, interleukin (IL)-6 and interferons that follows the administration of chloroquine might help counteract an exaggerated proinflammatory response, which is thought to contribute to the organ damage observed in SARS-CoV-2–infected patients [36,37].
T379 49201-49356 Sentence denotes However, some authors have pointed out that an unfavourable immunomodulatory effect cannot be excluded, based on a reduced T helper 2 differentiation [38].
T380 49357-49579 Sentence denotes In our opinion, hydroxychloroquine should be preferred over chloroquine because of its less toxic profile (reduced ocular toxicity and fewer drug interactions) and its more potent in vitro activity against SARS-CoV-2 [39].
T381 49580-49839 Sentence denotes Recently, Cortegiani et al. [40] reviewed the available information on ongoing case series, comparative observational studies and RCT evaluating the use of chloroquine or hydroxychloroquine in patients with COVID-19 and registered in Chinese or US registries.
T382 49840-49892 Sentence denotes They found 23 studies, all being conducted in China.
T383 49893-50082 Sentence denotes However, in the few weeks after the paper was made available online (10 March 2020), the number of registered studies being conducted in countries other than China has multiplied (Table 2).
T384 50083-50363 Sentence denotes In particular, results of registered RCT are necessary to guide (or discourage) the use of chloroquine/hydroxychloroquine in two different settings: prophylaxis of exposed individuals and treatment of proven cases, stratified for the severity of clinical presentation/progression.
T385 50364-50506 Sentence denotes In the meantime, a small controlled nonrandomized study of COVID-19 patients treated with hydroxychloroquine has been recently published [41].
T386 50507-50760 Sentence denotes In this study, Gautret et al. enrolled 26 COVID-19 patients to receive 200 mg of hydroxychloroquine every 8 hours for 10 days, whereas a total of 16 patients who denied consent as well as untreated patients from another centre were included as controls.
T387 50761-50842 Sentence denotes Of note, six patients treated with hydroxychloroquine also received azithromycin.
T388 50843-50977 Sentence denotes The primary endpoint was virologic clearance (based on results of real-time PCR on nasopharyngeal specimens) at day 6 after inclusion.
T389 50978-51333 Sentence denotes At day 6, 70% (14/20) of hydroxychloroquine-treated patients were virologically cured versus 12.5% (2/16) in the control group (p 0.001), although it cannot be excluded that selection bias and baseline virus load played a role in influencing results, thereby biasing results towards observing a favourable effect of hydroxychloroquine administration [42].
T390 51334-51565 Sentence denotes Furthermore, the opposite results (apparent absence of reduction of virus clearance) were recently described by another French group (albeit in a tiny sample size of 11 patients receiving hydroxychloroquine plus azithromycin) [43].
T391 51566-51914 Sentence denotes Uncertainty also surrounds the more marked positive effect observed in patients receiving azithromycin in addition to hydroxychloroquine in the study by Gautret et al., especially because of the very small number of patients in the combined treatment subgroup and the possible increased risk of QT prolongation by combining the two drugs (Table 3).
T392 51916-51936 Sentence denotes Question 3 statement
T393 51937-52195 Sentence denotes Pending results of RCT, the use of hydroxychloroquine may be considered for treating worsening patients with COVID-19 only if no important drug interactions can be anticipated and with close monitoring of hepatic function, renal function and QT prolongation.
T394 52196-52404 Sentence denotes This is based on its activity in vitro against SARS-CoV-2 (although weak) and on the availability of low-level clinical evidence of anticipation of virus clearance from a small controlled nonrandomized study.
T395 52405-52577 Sentence denotes However, it should also be kept in mind that the study was highly susceptible to bias and there are still no data regarding hard clinical endpoints such as crude mortality.
T396 52578-52702 Sentence denotes For these reasons, hydroxychloroquine should be preferentially administered within the framework of investigational studies.
T397 52703-52812 Sentence denotes When this is unfeasible, off-label use may be considered according to local protocols and consent procedures.
T398 52813-53009 Sentence denotes In view of the absence of evidence, we are currently unable to support the use of hydroxychloroquine in asymptomatic or mildly symptomatic nonhospitalized patients outside investigational studies.
T399 53010-53047 Sentence denotes The same applies to prophylactic use.
T400 53049-53096 Sentence denotes Question 4. should antibiotics be administered?
T401 53097-53299 Sentence denotes Bacterial infections can present simultaneously with COVID-19 or occur later during the course of the disease, worsening clinical conditions of patients who were recovering from primary viral pneumonia.
T402 53300-53400 Sentence denotes Information regarding the prevalence of bacterial coinfection or superinfection is scant [28,44,45].
T403 53401-53535 Sentence denotes According to the available reports, prevalence of bacterial infections in patients with COVID-19 ranges between 1% and 10% [28,44,46].
T404 53536-53668 Sentence denotes In these reports, bacterial infections were due to Gram-negative bacteria including Enterobacterales and nonfermenting rods [28,44].
T405 53669-53967 Sentence denotes It is of note that up to 98% of COVID-19 patients in available experiences received intravenous broad-spectrum empirical antibiotics [28,44,45,47], probably reflecting the frequent inability to exclude the presence of bacterial coinfection at the onset of severe clinical presentations of COVID-19.
T406 53968-54053 Sentence denotes This could have possibly lowered the overall prevalence of bacterial superinfections.
T407 54054-54296 Sentence denotes Extrapolating data from experiences on bacterial superinfection in pneumonia due to other viruses in a retrospective case series of critically ill patients with MERS in Saudi Arabia, bacterial infection was registered in 18% of patients [48].
T408 54297-54435 Sentence denotes With similar prevalence, bacterial pneumonia occurred in about 20% of patients hospitalized for primary influenza virus infection [49,50].
T409 54436-54541 Sentence denotes In these studies, mortality related to influenza was mostly due to secondary bacterial pneumonia [49,50].
T410 54542-54728 Sentence denotes Common bacteria implicated were Staphylococcus aureus, including methicillin-resistant strains [51], Streptococcus pneumoniae, Haemophilus influenzae and group A streptococci [49,52,53].
T411 54729-54900 Sentence denotes There are currently no large data regarding any possible favourable effects in COVID-19 patients related to possible anti-inflammatory or antiviral effect of azithromycin.
T412 54901-55029 Sentence denotes Furthermore, the small experiences of the administration of azithromycin in COVID-19 patients have provided conflicting results.
T413 55031-55051 Sentence denotes Question 4 statement
T414 55052-55234 Sentence denotes In our opinion, it might be prudent to consider empiric antibiotic treatment in critically ill patients with pneumonia due to COVID-19 in whom bacterial infection cannot be excluded.
T415 55235-55473 Sentence denotes This suggestion is based on the facts that bacterial coinfection is common in patients with viral pneumonia and that it can be associated with a substantial risk of delaying appropriate treatment, thereby potentially increasing mortality.
T416 55474-55721 Sentence denotes Because of the limited available data on both the microbiologic epidemiology (and the prevalence of antimicrobial resistance) of bacterial superinfections in COVID-19 patients, it is difficult to provide specific pathogen-oriented recommendations.
T417 55722-56136 Sentence denotes Therefore, pending further studies, we suggest to empirically treat COVID-19 patients according to their clinical syndrome (e.g. community-acquired pneumonia, hospital-acquired pneumonia), choosing the best antimicrobial agent or agents on the basis of local guidelines and local antibiotic susceptibility patterns, with early de-escalation or discontinuation according to microbiology results, whenever available.
T418 56138-56182 Sentence denotes Question 5. should steroids be administered?
T419 56183-56425 Sentence denotes So far, no RCT has been performed on corticosteroids administration in patients with COVID-19, and there are controversial opinions regarding the extrapolation of inference from previous studies in SARS-CoV-1 and MERS-CoV patients [15,54,55].
T420 56426-56834 Sentence denotes In an observational study conducted in 84 COVID-19 patients with acute respiratory distress syndrome (ARDS) in China, administration of methylprednisolone was associated with reduced progression to death (hazard ratio 0.38, 95% confidence interval 0.20–0.72, p 0.003), although the unadjusted analysis and the relatively small sample size preclude firm generalization and call for further investigation [47].
T421 56835-57051 Sentence denotes Indirect data on the possible efficacy (RCT) or effectiveness (observational comparative studies) of corticosteroid therapy come from studies performed in patients with MERS-CoV, SARS-CoV-1 or other viral infections.
T422 57052-57240 Sentence denotes With regard to patients with mild clinical presentation, a RCT including 16 not critically ill patients with SARS-CoV-1 did not report a beneficial effect of hydrocortisone administration.
T423 57241-57388 Sentence denotes Of note, higher viraemia was observed in the second and third weeks after infection in the hydrocortisone group compared to the control group [56].
T424 57389-57710 Sentence denotes Moreover, as reported in a systematic review and meta-analysis of observational studies on corticosteroids provided to patients with SARS-CoV-1, only four studies provided conclusive data, reporting no survival benefit and possible harms including avascular necrosis, psychosis, diabetes and delayed virus clearance [57].
T425 57711-57915 Sentence denotes In critically ill patients, corticosteroids may be provided to decrease the inflammation–coagulation–fibroproliferation observed during acute respiratory distress syndrome (ARDS) [[58], [59], [60], [61]].
T426 57916-58185 Sentence denotes A meta-analysis on corticosteroid use in ARDS including eight controlled studies reported a significant reduction in markers of systemic inflammation, pulmonary and extrapulmonary organ dysfunction scores, duration of mechanical ventilation and ICU length of stay [62].
T427 58186-58292 Sentence denotes A recent multicentre RCT included 277 patients with ARDS to assess the effects of dexamethasone treatment.
T428 58293-58439 Sentence denotes Patients in the study arm received dexamethasone 20 mg once daily from day 1 to day 5, which was reduced to 10 mg once daily from day 6 to day 10.
T429 58440-58719 Sentence denotes This study reported a significant reduction in duration of mechanical ventilation in the dexamethasone group than in the control group (between-group difference 4.8 days, p < 0.0001) and a significant reduction in mortality at 60 days (between-group difference −15.3%, p 0.0047).
T430 58720-58841 Sentence denotes The proportion of adverse events did not differ significantly between the dexamethasone group and the control group [63].
T431 58842-58990 Sentence denotes Data on the use of corticosteroids in critically ill patients with SARS-CoV-1 and MERS-CoV infection are available, albeit with conflicting results.
T432 58991-59239 Sentence denotes In a retrospective observational study of 152 SARS-CoV-1–infected, critically ill patients, corticosteroid therapy was found to reduce mortality and shorten the length of hospital stay (odds ratio 0.08, 95% confidence intervals 0.01–0.97, p 0.046).
T433 59240-59359 Sentence denotes The study did not report increased secondary infections or other complications with corticosteroid administration [64].
T434 59360-59594 Sentence denotes Conversely, in a retrospective observational study on 309 critically ill patients with MERS-CoV, the administration of a median hydrocortisone equivalent dose of 300 mg per day was not associated with a difference in 90-day mortality.
T435 59595-59734 Sentence denotes In addition, corticosteroid administration was associated with delayed clearance of MERS-CoV RNA from the patients' respiratory tract [65].
T436 59735-59976 Sentence denotes With regard to other viral infections, it is worth noting that a recent meta-analysis on patients with influenza pneumonia (including ten observational studies with a total of 6548 included patients) reported increased mortality (risk ratio:
T437 59977-60056 Sentence denotes 1.75, 95% CI 1.3–2.4; p 0.0002), increased length of ICU stay (mean difference:
T438 60057-60164 Sentence denotes 2.1, 95% CI 1.2–3.1; p < 0.0001) and increased rate of secondary bacterial or fungal infection (risk ratio:
T439 60165-60240 Sentence denotes 2.0, 95% CI 1.0–3.8; p 0.04) in patients who received corticosteroids [66].
T440 60242-60262 Sentence denotes Question 5 statement
T441 60263-60416 Sentence denotes So far, no definitive efficacy or effectiveness data are available on the benefit of corticosteroid administration in patients with SARS-CoV-2 infection.
T442 60417-60583 Sentence denotes As the World Health Organization underlines, there is an important need for efficacy data from RCT for supporting corticosteroids therapy in patients with SARS-CoV-2.
T443 60584-61045 Sentence denotes However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for the rapidly progressive pneumonia and clinical deterioration in COVID-19 patients [44,58,67], we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission).
T444 61046-61274 Sentence denotes However, in the absence of convincing evidence, the following cannot currently be supported: steroid administration stratified according to inflammatory markers and steroid administration in non–critically ill COVID-19 patients.
T445 61276-61369 Sentence denotes Question 6. should other immunosuppressive and/or immunomodulatory therapies be administered?
T446 61370-61655 Sentence denotes According to some recent evidence, some patients with COVID-19 may develop secondary haemophagocytic lymphohistiocytosis, an underrecognized hyperinflammatory syndrome characterized by a fulminant and fatal hypercytokinaemia, with development of ARDS and multiorgan failure [46,47,67].
T447 61656-61791 Sentence denotes Consequently, immunosuppressive and/or immunomodulatory therapies have been proposed to contrast COVID-19–associated hyperinflammation.
T448 61792-62164 Sentence denotes Tocilizumab is a recombinant humanized monoclonal antibody inhibiting membrane-bound and soluble IL-6 receptors [68] and is currently approved for the treatment of patients with rheumatoid arthritis, giant-cell arteritis, juvenile idiopathic arthritis and patients with chimeric antigen receptor T-cell–induced severe or life-threatening cytokine release syndrome [68,69].
T449 62165-62320 Sentence denotes In this regard, tocilizumab may help mitigate the cytokine release syndrome by decreasing cytokine concentrations and acute-phase reactant production [70].
T450 62321-62440 Sentence denotes In a recent preprint paper, Xu et al. [71] reported their experience of treating 21 COVID-19 patients with tocilizumab.
T451 62441-62831 Sentence denotes In their still-to-be-peer-reviewed case series, the following were observed after tocilizumab administration: (a) reduction in body temperature (21/21, 100%); (b) improved blood oxygenation (15/21, 71.4%); (c) normalization of lymphocyte count (10/17, 58.8%); (d) normalization of C-reactive protein (16/19, 82.4%); and (c) resolution of abnormalities on computed tomography (19/21, 90.5%).
T452 62832-62958 Sentence denotes Interestingly, no adverse reactions were observed after tocilizumab administration, but long-term follow-up was not available.
T453 62959-63117 Sentence denotes Tocilizumab has been deemed by Chinese National Health Commission to be a possible treatment option for patients with severe COVID-19 with elevated IL-6 [72].
T454 63118-63300 Sentence denotes The recommended dose is 4 to 8 mg/kg or 400 mg standard dose provided intravenously once, with the option to repeat a dose after 8 to 12 hours (not to exceed a total dose of 800 mg).
T455 63301-63498 Sentence denotes However, it should be noted that the optimal time for administering tocilizumab has not yet been fully elucidated; nor is there a clear IL-6 threshold associated with progression to severe disease.
T456 63499-63641 Sentence denotes At the time of writing, there are at least eight ongoing RCT evaluating the efficacy and safety of tocilizumab in COVID-19 patients (Table 2).
T457 63642-63838 Sentence denotes Other immune-modulatory drugs including anakinra (interleukin 1 receptor antagonist) or Janus kinase family enzyme inhibitors have been proposed for the management of SARS-CoV-2–infected patients.
T458 63839-63938 Sentence denotes Notably, there is currently no supporting clinical evidence, and RCT are ongoing (Table 2) [67,73].
T459 63939-64210 Sentence denotes Finally, modifications of the immune response through administration of high-dose intravenous immunoglobulin or convalescent plasma have also been proposed or used in small case series, and they merit further investigation in dedicated RCT [[74], [75], [76], [77], [78]].
T460 64212-64232 Sentence denotes Question 6 statement
T461 64233-64387 Sentence denotes Owing to the lack of high-level evidence, administration of tocilizumab in patients with COVID-19 should preferentially occur within the framework of RCT.
T462 64388-64714 Sentence denotes Off-label use according to local protocols and consent procedures may be considered only in those COVID-19 patients excluded from RCT (or hospitalized where RCT are not available or still to be implemented) and who are worsening while receiving standard supportive care (in the absence of concomitant/superimposed infections).
T463 64715-65191 Sentence denotes In our opinion, this could be a reasonable off-label use of tocilizumab in these early phases of the COVID-19 pandemic, although patients and physicians should be fully aware that currently there is only a non–peer-reviewed, noncomparative, observational experience (very low evidence from an unreviewed cases series), and that it only supports a potential favourable effect on inflammatory signs and symptoms, while there is no information on any possible effect on survival.
T464 65192-65411 Sentence denotes In the absence of clinical studies, we suggest that also other immunosuppressive and/or immunomodulatory therapies (e.g. anakinra, Janus kinase family enzyme inhibitors) should be preferentially administered within RCT.
T465 65412-65750 Sentence denotes This also applies to modifications of the immune response through high-dose intravenous immunoglobulins or plasma from convalescent patients, which, although promising in very small case series, both deserve dedicated RCT investigation to clearly understand their tolerability as well as the role they play in affecting COVID-19 outcomes.
T466 65752-65815 Sentence denotes Question 7. what is the optimal timing of treatment initiation?
T467 65816-66016 Sentence denotes Most clinical data on the timing of antiviral therapy initiation are derived from studies on viruses other than SARS-CoV-2, and it remains unclear whether these data can be extrapolated to SARS-CoV-2.
T468 66017-66200 Sentence denotes Previous studies in SARS-CoV-1 and influenza showed a possible favourable impact on mortality of early initiation of antiviral treatment after symptoms onset [[79], [80], [81], [82]].
T469 66201-66604 Sentence denotes With regard to SARS-CoV-2, although the results of the previously cited RCT comparing LPV/RTV versus standard of care eventually does not support the use of LPV/RTV in patients with COVID-19, it is also of note that the median time between symptom onset and randomization was 13 days (interquartile range, 11–16 days), so in most cases, the drug was initiated late during the course of the disease [22].
T470 66605-66733 Sentence denotes Consequently, we cannot exclude the possibility that an earlier initiation of LPV/RTV may be associated with improved prognosis.
T471 66734-66953 Sentence denotes In this regard, we think the results of this RCT may be hypothesis generating and may help guide the design of further RCT evaluating the efficacy of LPV/RTV (and/or other antivirals) in an earlier phase of the disease.
T472 66954-67201 Sentence denotes However, until such RCT will be available, we think the currently available clinical evidence is insufficient to support the use of LPV/RTV and/or other antivirals for treating COVID-19 outside the framework of RCT or compassionate-use programmes.
T473 67202-67306 Sentence denotes The optimal time of chloroquine/hydroxychloroquine and corticosteroids initiation still remains unknown.
T474 67307-67803 Sentence denotes Although based on low-level evidence, the positive effect of virus clearance observed by Gautret et al. [41] was observed in a mixed group of non-ICU patients with upper respiratory tract symptoms, non-ICU patients with lower respiratory tract symptoms and asymptomatic subjects, which overall may support a positive effect of early hydroxychloroquine initiation in non-ICU settings (although information on the exact time of treatment initiation with respect to symptoms onset was not provided).
T475 67804-67951 Sentence denotes With regard to steroid treatment, there is currently no evidence of a positive impact of early initiation in non–critically ill, non-ARDS patients.
T476 67952-68210 Sentence denotes Although lack of evidence is not a synonym of lack of effect, in our opinion, steroid treatment, considering also its potential detrimental effects, should currently be limited to ARDS patients or non-ARDS patients with worsening conditions (see question 5).
T477 68212-68232 Sentence denotes Question 7 statement
T478 68233-68529 Sentence denotes Supportive therapy (symptomatic therapy, rehydration and oxygen supplementation, if necessary) should be provided as soon as the patient presents with respiratory or systemic symptoms including severe asthenia, high fever, persistent cough and/or clinical or radiologic signs of lung involvement.
T479 68530-68801 Sentence denotes Pending further evidence, in our opinion, antiviral treatments should not be initiated in patients with SARS-CoV-2 infection outside RCT or compassionate-use programmes (with the exception of early oseltamivir initiation in patients with suspected concomitant influenza).
T480 68802-69074 Sentence denotes Corticosteroids should be initiated early in well-defined categories of patients (patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections), while their role in other COVID-19 patients still remains uncertain.
T481 69075-69458 Sentence denotes Although based on low-level evidence and pending RCT results, in our opinion, early hydroxychloroquine administration may be considered in COVID-19 patients who have moderate to severe symptoms, whereas further data are needed to better delineate the true balance between possible favourable effects and toxicity of hydroxychloroquine in mildly symptomatic and asymptomatic patients.
T482 69460-69511 Sentence denotes Question 8. what is the optimal treatment duration?
T483 69512-69815 Sentence denotes In the absence of proven effective treatment, treatment duration also remains unclear; it is currently based on expert opinion which is based on treatment durations in other approved indications for the drugs provided and aimed at a balance between potential activity and risk of undesired side effects.
T484 69816-69863 Sentence denotes Nonetheless, suggested durations vary markedly.
T485 69864-70269 Sentence denotes For example, a wide range of chloroquine/hydroxychloroquine treatment durations (from 5 to 20 days) have been recommended/provided in different centres/studies, making it impossible to provide an univocal recommendation in the absence of direct comparisons of different lengths of treatment with regard to relevant clinical endpoints (e.g. mortality, ICU admission) and safety [33,40,41,[83], [84], [85]].
T486 70270-70431 Sentence denotes There is no standard steroid treatment duration, with different consensus/study groups suggesting steroid administration for no longer than 7 to 10 days [54,85].
T487 70433-70453 Sentence denotes Question 8 statement
T488 70454-70761 Sentence denotes Chloroquine/hydroxychloroquine treatment should be continued for at least 5 days and possibly prolonged up to 20 days according to some expert opinions, although it should be noted that data regarding the relative safety of different lengths of administration in COVID-19 patients are currently unavailable.
T489 70762-70898 Sentence denotes Early discontinuation should be considered in the presence of adverse effects (e.g. QT prolongation or hepatic/renal toxicity; Table 3).
T490 70899-71176 Sentence denotes If the administration of remdesivir is approved within compassionate-use/expanded-access programmes, treatment duration should follow compassionate or expanded access protocols (e.g. up to 10 days according to the most recent compassionate protocol at the time of this review).
T491 71177-71301 Sentence denotes If corticosteroids are administered, we suggest a total treatment duration of 7 to 10 days, with progressive dose reduction.
T492 71302-71557 Sentence denotes If the patient deteriorates with worsening lung physiology after removal of steroid treatment in the absence of bacterial or fungal superinfection, a second course of corticosteroid treatment may be considered, followed by slow tapering after improvement.
T493 71559-71578 Sentence denotes Future perspectives
T494 71579-72089 Sentence denotes In these first phases of the COVID-19 pandemic, where there are no clearly supported and approved treatments, there are two apparently mutually exclusive forces driving therapeutic choices supported only by preclinical and/or low-level clinical evidence: the willingness to administer potentially active therapies to COVID-19 patients; and the willingness not to harm by administering potentially inactive therapies that may unfavourably influence the outcome because of either expected or unexpected toxicity.
T495 72090-72262 Sentence denotes Finding the right balance between these two forces is certainly not simple, but it remains more necessary than ever if we want to rapidly find effective and safe treatment.
T496 72263-72476 Sentence denotes For this reason, RCT should always be the first option to be proposed to patients because RCT are the only way to provide high-level efficacy and safety information for optimizing the treatment of future patients.
T497 72477-72792 Sentence denotes However, even when rapidly implemented during evolving pandemics, RCT are usually not immediately available (e.g. even if accelerated, local approval still and correctly requires time to guarantee ethical standards), and also many patients are usually excluded from RCT because of strict selection criteria [86,87].
T498 72793-73086 Sentence denotes For some of these patients, off-label uses (for drugs approved for other indications) and compassionate-use/expanded-access programmes (for investigational drugs) may represent an ethically justifiable option in the case of worsening conditions and unlikely survival with only supportive care.
T499 73087-73284 Sentence denotes Against this background, the role of the attending physician is crucial, by favouring and not discouraging RCT participation (in favour of off-label administration) whenever the former is possible.
T500 73285-73559 Sentence denotes Otherwise, scientific data will still be produced, but most information will be burdened by only partially adjustable selection biases and confounding factors, with consequent risks of inconclusive results and low-level supporting evidence for the various treatment options.
T501 73560-73850 Sentence denotes If participation in RCT is maximized, high-level evidence will be available for guiding treatment, with lower-level evidence from off-label uses still remaining useful for hypothesis-generating purposes in order to better design further RCT (and not for directly guiding treatment choices).
T502 73851-74320 Sentence denotes Notably, this is what, in our opinion, happened with LPV/RTV: (a) preclinical data supported activity against coronaviruses; (b) patients were enrolled onto RCT whenever possible, and otherwise they were offered off-label administration when not spontaneously improving; (c) because many patients were rapidly enrolled onto the first RCT, evidence rapidly become available that in our opinion discouraged a universal off-label provision of LPV/RTV in COVID-19 patients.
T503 74322-74333 Sentence denotes Conclusions
T504 74334-74455 Sentence denotes Many off-label antiviral and anti-inflammatory drugs are being administered in this first phase of the COVID-19 pandemic.
T505 74456-74717 Sentence denotes While we do not discourage their use, physicians must be aware that because of the lack of high-level evidence, they may be ethically justifiable only in those worsening patients unlikely to improve with only supportive care and who cannot be enrolled onto RCT.
T506 74718-74919 Sentence denotes Implementation of well-designed RCT should be expanded as much as possible, as RCTs are the most secure way to change for the better our approach to COVID-19 patients, including our frontline opinions.
T507 74921-74945 Sentence denotes Transparency Declaration
T508 74946-75015 Sentence denotes All authors report no conflicts of interest relevant to this article.

2_test

Id Subject Object Predicate Lexical cue
32360444-32178769-22369750 2644-2645 32178769 denotes 6
32360444-32119825-22369751 2775-2776 32119825 denotes 7
32360444-32187464-22369752 15638-15640 32187464 denotes 22
32360444-32105632-22369753 35779-35780 32105632 denotes 9
32360444-25981908-22369754 36624-36626 25981908 denotes 12
32360444-19467849-22369755 36630-36632 19467849 denotes 13
32360444-28860265-22369756 36636-36638 28860265 denotes 14
32360444-32105632-22369757 36953-36954 32105632 denotes 9
32360444-32105633-22369758 37335-37337 32105633 denotes 16
32360444-23688302-22369759 39111-39113 23688302 denotes 18
32360444-27585965-22369760 40604-40606 27585965 denotes 19
32360444-27344959-22369761 40610-40612 27344959 denotes 20
32360444-26198719-22369762 40616-40618 26198719 denotes 21
32360444-32187464-22369763 40760-40762 32187464 denotes 22
32360444-32020029-22369764 45217-45219 32020029 denotes 23
32360444-31924756-22369765 45223-45225 31924756 denotes 24
32360444-32054787-22369766 45229-45231 32054787 denotes 25
32360444-15200845-22369767 45854-45856 15200845 denotes 27
32360444-32007143-22369768 46042-46044 32007143 denotes 28
32360444-32147628-22369769 46474-46476 32147628 denotes 29
32360444-32251768-22369770 47444-47446 32251768 denotes 31
32360444-15351731-22369771 48828-48830 15351731 denotes 32
32360444-32203437-22369772 48846-48848 32203437 denotes 35
32360444-9002011-22369773 49193-49195 9002011 denotes 36
32360444-32194152-22369774 49575-49577 32194152 denotes 39
32360444-32007143-22369775 53390-53392 32007143 denotes 28
32360444-31986264-22369776 53393-53395 31986264 denotes 44
32360444-32109013-22369777 53396-53398 32109013 denotes 45
32360444-32007143-22369778 53525-53527 32007143 denotes 28
32360444-31986264-22369779 53528-53530 31986264 denotes 44
32360444-32007143-22369780 53661-53663 32007143 denotes 28
32360444-31986264-22369781 53664-53666 31986264 denotes 44
32360444-32007143-22369782 53803-53805 32007143 denotes 28
32360444-31986264-22369783 53806-53808 31986264 denotes 44
32360444-32109013-22369784 53809-53811 32109013 denotes 45
32360444-31573350-22369785 54292-54294 31573350 denotes 48
32360444-22387143-22369786 54428-54430 22387143 denotes 49
32360444-20508031-22369787 54431-54433 20508031 denotes 50
32360444-22387143-22369788 54534-54536 22387143 denotes 49
32360444-20508031-22369789 54537-54539 20508031 denotes 50
32360444-16707043-22369790 54638-54640 16707043 denotes 51
32360444-22387143-22369791 54718-54720 22387143 denotes 49
32360444-22291193-22369792 54721-54723 22291193 denotes 52
32360444-20377405-22369793 54724-54726 20377405 denotes 53
32360444-32122468-22369794 56418-56420 32122468 denotes 54
32360444-32043983-22369795 56421-56423 32043983 denotes 55
32360444-15494274-22369796 57384-57386 15494274 denotes 56
32360444-16968120-22369797 57706-57708 16968120 denotes 57
32360444-22088618-22369798 57892-57894 22088618 denotes 58
32360444-7587435-22369799 57898-57900 7587435 denotes 59
32360444-11934726-22369800 57904-57906 11934726 denotes 60
32360444-21983371-22369801 57910-57912 21983371 denotes 61
32360444-19325471-22369802 58181-58183 19325471 denotes 62
32360444-32043986-22369803 58837-58839 32043986 denotes 63
32360444-16778260-22369804 59355-59357 16778260 denotes 64
32360444-29161116-22369805 59730-59732 29161116 denotes 65
32360444-30917856-22369806 60236-60238 30917856 denotes 66
32360444-31986264-22369807 60777-60779 31986264 denotes 44
32360444-22088618-22369808 60780-60782 22088618 denotes 58
32360444-32192578-22369809 60783-60785 32192578 denotes 67
32360444-32192578-22369810 61651-61653 32192578 denotes 67
32360444-24834925-22369811 61905-61907 24834925 denotes 68
32360444-24834925-22369812 62157-62159 24834925 denotes 68
32360444-18358927-22369813 62160-62162 18358927 denotes 69
32360444-32192578-22369814 63931-63933 32192578 denotes 67
32360444-32032529-22369815 63934-63936 32032529 denotes 73
32360444-32167489-22369816 64181-64183 32167489 denotes 74
32360444-32258207-22369817 64199-64201 32258207 denotes 77
32360444-32178711-22369818 64205-64207 32178711 denotes 78
32360444-14660806-22369819 66177-66179 14660806 denotes 79
32360444-30304487-22369820 66183-66185 30304487 denotes 80
32360444-22843781-22369821 66189-66191 22843781 denotes 81
32360444-24815805-22369822 66195-66197 24815805 denotes 82
32360444-32187464-22369823 66600-66602 32187464 denotes 22
32360444-32164085-22369824 70258-70260 32164085 denotes 84
32360444-32122468-22369825 70424-70426 32122468 denotes 54
32360444-29240890-22369826 72785-72787 29240890 denotes 86
32360444-31607179-22369827 72788-72790 31607179 denotes 87