> top > docs > PMC:7190487 > spans > 4638-5573 > annotations

PMC:7190487 / 4638-5573 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T29 37-40 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T30 134-151 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T31 146-151 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 219-236 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T33 231-236 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T34 837-842 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T27 0-4 Disease denotes Zika http://purl.obolibrary.org/obo/MONDO_0018661
T28 677-685 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 804-812 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 926-934 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T60 5-10 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T61 19-20 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T62 41-46 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T63 51-52 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 53-61 http://purl.obolibrary.org/obo/NCBITaxon_7157 denotes mosquito
T65 86-87 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T66 100-106 http://purl.obolibrary.org/obo/CLO_0004307 denotes HUVECs
T67 111-116 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T68 134-151 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T69 219-236 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T70 243-253 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activation
T71 299-309 http://purl.obolibrary.org/obo/CLO_0001658 denotes activators
T72 419-428 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activated
T73 480-485 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T74 549-552 http://purl.obolibrary.org/obo/CLO_0009915 denotes MX1
T75 689-690 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T76 704-707 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T77 830-836 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T78 830-836 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T79 830-836 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T80 830-836 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T81 837-842 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T82 879-880 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T67 117-124 Chemical denotes retinal http://purl.obolibrary.org/obo/CHEBI_15035
T68 294-309 Chemical denotes AMPK activators http://purl.obolibrary.org/obo/CHEBI_85053
T69 311-320 Chemical denotes metformin http://purl.obolibrary.org/obo/CHEBI_6801
T70 325-355 Chemical denotes 5-aminoimidazole-4-carboxamide http://purl.obolibrary.org/obo/CHEBI_2030
T71 327-341 Chemical denotes aminoimidazole http://purl.obolibrary.org/obo/CHEBI_22512
T72 344-355 Chemical denotes carboxamide http://purl.obolibrary.org/obo/CHEBI_23004|http://purl.obolibrary.org/obo/CHEBI_37622
T74 356-370 Chemical denotes ribonucleotide http://purl.obolibrary.org/obo/CHEBI_26561
T75 372-377 Chemical denotes AICAR http://purl.obolibrary.org/obo/CHEBI_18406
T76 497-506 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T77 779-781 Chemical denotes DG http://purl.obolibrary.org/obo/CHEBI_73450
T78 908-917 Chemical denotes metformin http://purl.obolibrary.org/obo/CHEBI_6801

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T44 173-177 http://purl.obolibrary.org/obo/GO_0050405 denotes AMPK
T45 173-177 http://purl.obolibrary.org/obo/GO_0047322 denotes AMPK
T46 173-177 http://purl.obolibrary.org/obo/GO_0004691 denotes AMPK
T47 257-261 http://purl.obolibrary.org/obo/GO_0050405 denotes AMPK
T48 257-261 http://purl.obolibrary.org/obo/GO_0047322 denotes AMPK
T49 257-261 http://purl.obolibrary.org/obo/GO_0004691 denotes AMPK
T50 294-298 http://purl.obolibrary.org/obo/GO_0050405 denotes AMPK
T51 294-298 http://purl.obolibrary.org/obo/GO_0047322 denotes AMPK
T52 294-298 http://purl.obolibrary.org/obo/GO_0004691 denotes AMPK
T53 429-433 http://purl.obolibrary.org/obo/GO_0050405 denotes AMPK
T54 429-433 http://purl.obolibrary.org/obo/GO_0047322 denotes AMPK
T55 429-433 http://purl.obolibrary.org/obo/GO_0004691 denotes AMPK
T56 722-746 http://purl.obolibrary.org/obo/GO_0045820 denotes inhibition of glycolysis
T57 736-746 http://purl.obolibrary.org/obo/GO_0006096 denotes glycolysis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T41 0-85 Sentence denotes Zika virus (ZIKV), a single-stranded RNA virus, is a mosquito transmitted flavivirus.
T42 86-242 Sentence denotes A study using HUVECs and human retinal vascular endothelial cells (HRvECs) showed that AMPK restricts the replication of ZIKV in the endothelial cells [16].
T43 243-418 Sentence denotes Activation of AMPK with the help of two well-known AMPK activators, metformin and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) led to attenuation of ZIKV replication.
T44 419-613 Sentence denotes Activated AMPK further potentiated the expression of certain genes with known antiviral properties such as IFNs, OAS2, ISG15, and MX1 while inhibiting inflammatory mediators like TNF-α and CCL5.
T45 614-688 Sentence denotes It would be useful to explore whether the same is observed for SARS-CoV-2.
T46 689-848 Sentence denotes A recent study has reported that inhibition of glycolysis by non-toxic concentration of 2-DG completely attenuated SARS-CoV-2 replication in Caco-2 cells [17].
T47 849-935 Sentence denotes All of these indicate towards a possible frontline role of metformin against COVID-19.

2_test

Id Subject Object Predicate Lexical cue
32360697-32086387-25244891 238-240 32086387 denotes 16

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
216 173-177 Gene denotes AMPK Gene:5563
217 257-261 Gene denotes AMPK Gene:5563
218 294-298 Gene denotes AMPK Gene:5563
219 429-433 Gene denotes AMPK Gene:5563
220 532-536 Gene denotes OAS2 Gene:4939
221 538-543 Gene denotes ISG15 Gene:9636
222 549-552 Gene denotes MX1 Gene:4599
223 598-603 Gene denotes TNF-α Gene:7124
224 608-612 Gene denotes CCL5 Gene:6352
225 0-10 Species denotes Zika virus Tax:64320
226 12-16 Species denotes ZIKV Tax:64320
227 19-46 Species denotes a single-stranded RNA virus Tax:674971
228 111-116 Species denotes human Tax:9606
229 207-211 Species denotes ZIKV Tax:64320
230 401-405 Species denotes ZIKV Tax:64320
231 677-687 Species denotes SARS-CoV-2 Tax:2697049
232 804-814 Species denotes SARS-CoV-2 Tax:2697049
233 311-320 Chemical denotes metformin MESH:D008687
234 325-370 Chemical denotes 5-aminoimidazole-4-carboxamide ribonucleotide MESH:C031143
235 372-377 Chemical denotes AICAR MESH:C031143
236 777-781 Chemical denotes 2-DG MESH:D003847
237 908-917 Chemical denotes metformin MESH:D008687
238 926-934 Disease denotes COVID-19 MESH:C000657245
239 830-836 CellLine denotes Caco-2 CVCL:0025