> top > docs > PMC:7189872 > spans > 13727-15473 > annotations

PMC:7189872 / 13727-15473 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
267 509-514 Gene denotes HLA-A Gene:3105
268 525-530 Gene denotes MHC I
269 531-534 Gene denotes HLA Gene:3123
270 549-558 Chemical denotes Threonine MESH:D013912
271 625-633 Chemical denotes hydrogen MESH:D006859
272 731-744 Chemical denotes Glutamic acid MESH:D018698
273 749-755 Chemical denotes lysine MESH:D008239
280 941-946 Gene denotes HLA-A Gene:3105
281 957-962 Gene denotes MHC I
282 963-966 Gene denotes HLA Gene:3123
283 981-990 Chemical denotes Threonine MESH:D013912
284 1027-1035 Chemical denotes cysteine MESH:D003545
285 1090-1098 Chemical denotes hydrogen MESH:D006859
293 1307-1315 Gene denotes HLA-DRB1 Gene:3123
294 1332-1335 Gene denotes HLA Gene:3123
295 1350-1358 Chemical denotes Tyrosine MESH:D014443
296 1367-1376 Chemical denotes Glutamine MESH:D005973
297 1397-1403 Chemical denotes Serine MESH:D012694
298 1453-1461 Chemical denotes hydrogen MESH:D006859
299 1549-1560 Chemical denotes 7tharginine
301 1729-1732 Gene denotes HLA Gene:3123
306 117-120 Gene denotes HLA Gene:3123
307 98-101 Gene denotes MHC Gene:3107
308 425-428 Gene denotes HLA Gene:3123
309 133-141 Chemical denotes hydrogen MESH:D006859

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T135 68-72 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T136 98-101 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T137 117-120 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T138 425-428 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T139 509-512 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T140 525-528 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T141 531-534 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T142 549-558 Body_part denotes Threonine http://purl.org/sig/ont/fma/fma82765
T143 731-744 Body_part denotes Glutamic acid http://purl.org/sig/ont/fma/fma82762
T144 749-755 Body_part denotes lysine http://purl.org/sig/ont/fma/fma82758
T145 820-831 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T146 941-944 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T147 957-960 Body_part denotes MHC http://purl.org/sig/ont/fma/fma84079
T148 963-966 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T149 981-990 Body_part denotes Threonine http://purl.org/sig/ont/fma/fma82765
T150 1027-1035 Body_part denotes cysteine http://purl.org/sig/ont/fma/fma82751
T151 1186-1197 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T152 1307-1310 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T153 1332-1335 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795
T154 1350-1358 Body_part denotes Tyrosine http://purl.org/sig/ont/fma/fma82768
T155 1367-1376 Body_part denotes Glutamine http://purl.org/sig/ont/fma/fma82752
T156 1397-1403 Body_part denotes Serine http://purl.org/sig/ont/fma/fma82764
T157 1617-1628 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T158 1729-1732 Body_part denotes HLA http://purl.org/sig/ont/fma/fma84795

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T102 49-50 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 66-72 http://purl.obolibrary.org/obo/CL_0000084 denotes T-Cell
T104 360-361 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 513-514 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T106 623-624 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 793-794 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 945-946 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T109 1088-1089 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 1451-1452 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T111 1590-1591 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T94 114-116 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T95 133-141 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T96 483-490 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T97 595-602 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T98 625-633 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T99 702-707 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T100 731-744 Chemical denotes Glutamic acid http://purl.obolibrary.org/obo/CHEBI_18237
T101 740-744 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T102 749-755 Chemical denotes lysine http://purl.obolibrary.org/obo/CHEBI_18019|http://purl.obolibrary.org/obo/CHEBI_25094
T104 795-799 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T106 820-831 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T107 820-825 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T108 826-831 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T109 915-922 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T110 1027-1035 Chemical denotes cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T111 1059-1066 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T112 1090-1098 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T113 1167-1172 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T114 1186-1197 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T115 1186-1191 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T116 1192-1197 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T117 1281-1288 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T118 1350-1358 Chemical denotes Tyrosine http://purl.obolibrary.org/obo/CHEBI_17895|http://purl.obolibrary.org/obo/CHEBI_18186
T120 1367-1376 Chemical denotes Glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T121 1397-1403 Chemical denotes Serine http://purl.obolibrary.org/obo/CHEBI_17115|http://purl.obolibrary.org/obo/CHEBI_17822
T123 1423-1430 Chemical denotes epitope http://purl.obolibrary.org/obo/CHEBI_53000
T124 1453-1461 Chemical denotes hydrogen http://purl.obolibrary.org/obo/CHEBI_49637
T125 1530-1535 Chemical denotes atoms http://purl.obolibrary.org/obo/CHEBI_33250
T126 1592-1596 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T128 1617-1628 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T129 1617-1622 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T130 1623-1628 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T16 147-156 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T125 0-200 Sentence denotes In Fig. 3, Fig. 4, Fig. 5 , interactions between a selected three T-Cell epitopes with respective MHC Class I and II HLA-Alleles via hydrogen bond formation and van der Waals interactions is depicted.
T126 201-341 Sentence denotes After positive docking results, these epitopes were subjected to further Molecular dynamic simulation and biochemical parameters assessment.
T127 342-437 Sentence denotes Fig. 6 represents a graphical plot of binding scores for epitopes interacting with HLA-Alleles.
T128 438-542 Sentence denotes Fig. 3 FTIGTVTLK Epitope interaction with an antigen-binding pocket of HLA-A*68:01, of MHC I-HLA Allele.
T129 543-869 Sentence denotes Here, Threonine at 2nd,5th, and 7th position in the epitope generate preferably a hydrogen bond due to the presence of partially charged positive and negative atoms, and also 4th position Glutamic acid and lysine at 8th position side chains can form a salt bridge, while other amino acids result in van der Waals interactions.
T130 870-974 Sentence denotes Fig. 4 ITLCFTLKR Epitope interaction with an antigen-binding pocket of HLA-A*68:01, of MHC I-HLA Allele.
T131 975-1235 Sentence denotes Here, Threonine at 2nd and 6th position, as well as cysteine at the 4th position in epitope, generate preferably a hydrogen bond due to the presence of partially charged positive and negative atoms, while other amino acids result in van der Waals interactions.
T132 1236-1666 Sentence denotes Fig. 5 VYQLRARSV Epitope interaction with an antigen-binding pocket of HLA-DRB1*07:01, of MHCII-HLA Allele, Here, Tyrosine at 2nd, Glutamine at 3rd position and Serine at 8th position in epitope generate preferably a hydrogen bond due to the presence of partially charged positive and negative atoms, and 5th and 7tharginine residue side chains can form a salt bridge, while other amino acids result in van der Waals interactions.
T133 1667-1746 Sentence denotes Fig. 6 Binding energy graphical plot for selected Epitope and HLA-Allelic pair.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T249 66-72 CL:0000084;BV_24 denotes T-Cell
T250 73-81 BV_24 denotes epitopes
T251 98-109 GO:0042613 denotes MHC Class I
T252 117-120 PR:000029150 denotes HLA
T253 121-128 SO:0001023 denotes Alleles
T254 239-247 BV_9 denotes epitopes
T255 399-407 BV_9 denotes epitopes
T256 429-436 SO:0001023 denotes Alleles
T257 455-462 BV_9 denotes Epitope
T258 483-490 CHEBI:59132;CHEBI:59132 denotes antigen
T259 509-514 PR:000002009 denotes HLA-A
T260 525-530 GO:0042613 denotes MHC I
T261 535-541 SO:0001023 denotes Allele
T262 595-602 BV_9 denotes epitope
T263 702-707 CHEBI:33250;CHEBI:33250 denotes atoms
T264 772-783 CHEBI:50325;CHEBI:50325 denotes side chains
T265 795-799 CHEBI:24866;CHEBI:24866 denotes salt
T266 887-894 BV_9 denotes Epitope
T267 915-922 CHEBI:59132;CHEBI:59132 denotes antigen
T268 941-946 PR:000002009 denotes HLA-A
T269 957-962 GO:0042613 denotes MHC I
T270 967-973 SO:0001023 denotes Allele
T271 1059-1066 BV_9 denotes epitope
T272 1167-1172 CHEBI:33250;CHEBI:33250 denotes atoms
T273 1253-1260 BV_9 denotes Epitope
T274 1281-1288 CHEBI:59132;CHEBI:59132 denotes antigen
T275 1307-1315 PR:000002019 denotes HLA-DRB1
T276 1326-1331 GO:0042611 denotes MHCII
T277 1336-1342 SO:0001023 denotes Allele
T278 1423-1430 BV_9 denotes epitope
T279 1530-1535 CHEBI:33250;CHEBI:33250 denotes atoms
T280 1569-1580 CHEBI:50325;CHEBI:50325 denotes side chains
T281 1592-1596 CHEBI:24866;CHEBI:24866 denotes salt
T282 1717-1724 BV_9 denotes Epitope
T283 1733-1740 SO:0001023 denotes Allelic