PMC:7187150 / 76-547 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T2","span":{"begin":136,"end":141},"obj":"Body_part"},{"id":"T3","span":{"begin":181,"end":206},"obj":"Body_part"},{"id":"T4","span":{"begin":201,"end":206},"obj":"Body_part"},{"id":"T5","span":{"begin":214,"end":219},"obj":"Body_part"},{"id":"T6","span":{"begin":227,"end":232},"obj":"Body_part"},{"id":"T7","span":{"begin":242,"end":249},"obj":"Body_part"},{"id":"T8","span":{"begin":265,"end":270},"obj":"Body_part"},{"id":"T9","span":{"begin":272,"end":278},"obj":"Body_part"},{"id":"T10","span":{"begin":283,"end":296},"obj":"Body_part"},{"id":"T11","span":{"begin":283,"end":288},"obj":"Body_part"},{"id":"T12","span":{"begin":352,"end":364},"obj":"Body_part"},{"id":"T13","span":{"begin":369,"end":375},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma62499"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma7203"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T2","span":{"begin":265,"end":270},"obj":"Body_part"},{"id":"T3","span":{"begin":272,"end":296},"obj":"Body_part"},{"id":"T4","span":{"begin":272,"end":278},"obj":"Body_part"},{"id":"T5","span":{"begin":283,"end":296},"obj":"Body_part"},{"id":"T6","span":{"begin":283,"end":288},"obj":"Body_part"},{"id":"T7","span":{"begin":289,"end":296},"obj":"Body_part"},{"id":"T8","span":{"begin":352,"end":364},"obj":"Body_part"},{"id":"T9","span":{"begin":352,"end":357},"obj":"Body_part"},{"id":"T10","span":{"begin":358,"end":364},"obj":"Body_part"},{"id":"T11","span":{"begin":369,"end":375},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0003517"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T3","span":{"begin":12,"end":20},"obj":"Disease"},{"id":"T4","span":{"begin":43,"end":90},"obj":"Disease"},{"id":"T5","span":{"begin":43,"end":76},"obj":"Disease"},{"id":"T6","span":{"begin":92,"end":100},"obj":"Disease"},{"id":"T7","span":{"begin":324,"end":332},"obj":"Disease"},{"id":"T8","span":{"begin":400,"end":409},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T5","span":{"begin":110,"end":115},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T6","span":{"begin":136,"end":141},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T7","span":{"begin":190,"end":219},"obj":"http://purl.obolibrary.org/obo/CL_0000082"},{"id":"T8","span":{"begin":227,"end":232},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T9","span":{"begin":265,"end":270},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T10","span":{"begin":265,"end":270},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T11","span":{"begin":265,"end":270},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T12","span":{"begin":265,"end":270},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T13","span":{"begin":272,"end":278},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T14","span":{"begin":272,"end":278},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T15","span":{"begin":272,"end":278},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T16","span":{"begin":283,"end":296},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T17","span":{"begin":283,"end":296},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T18","span":{"begin":346,"end":351},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T19","span":{"begin":352,"end":364},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T20","span":{"begin":352,"end":364},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T21","span":{"begin":369,"end":375},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T22","span":{"begin":369,"end":375},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T23","span":{"begin":369,"end":375},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T24","span":{"begin":427,"end":435},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":122,"end":135},"obj":"http://purl.obolibrary.org/obo/GO_0044409"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T2","span":{"begin":0,"end":104},"obj":"Sentence"},{"id":"T3","span":{"begin":105,"end":297},"obj":"Sentence"},{"id":"T4","span":{"begin":298,"end":471},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"13","span":{"begin":146,"end":150},"obj":"Gene"},{"id":"14","span":{"begin":456,"end":460},"obj":"Gene"},{"id":"15","span":{"begin":43,"end":90},"obj":"Species"},{"id":"16","span":{"begin":92,"end":102},"obj":"Species"},{"id":"17","span":{"begin":324,"end":334},"obj":"Species"},{"id":"18","span":{"begin":346,"end":351},"obj":"Species"},{"id":"19","span":{"begin":430,"end":435},"obj":"Species"},{"id":"20","span":{"begin":12,"end":20},"obj":"Disease"},{"id":"21","span":{"begin":400,"end":409},"obj":"Disease"}],"attributes":[{"id":"A13","pred":"tao:has_database_id","subj":"13","obj":"Gene:59272"},{"id":"A14","pred":"tao:has_database_id","subj":"14","obj":"Gene:59272"},{"id":"A15","pred":"tao:has_database_id","subj":"15","obj":"Tax:2697049"},{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"Tax:2697049"},{"id":"A17","pred":"tao:has_database_id","subj":"17","obj":"Tax:2697049"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"Tax:9606"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Tax:9606"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"MESH:C000657245"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus gains entry to host cells via ACE2, which is expressed by type 2 alveolar epithelial cells in the lungs and by cells in other tissues, including the heart, kidney and blood vessels. Researchers now show that SARS-CoV-2 can infect human blood vessel and kidney organoids and that this infection can be inhibited by human recombinant soluble ACE2 (hrsACE2)."}