PMC:7172841 / 17999-18297 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T109","span":{"begin":222,"end":227},"obj":"Body_part"},{"id":"T110","span":{"begin":237,"end":246},"obj":"Body_part"}],"attributes":[{"id":"A109","pred":"fma_id","subj":"T109","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A110","pred":"fma_id","subj":"T110","obj":"http://purl.org/sig/ont/fma/fma62864"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T168","span":{"begin":65,"end":74},"obj":"Disease"},{"id":"T169","span":{"begin":85,"end":93},"obj":"Disease"},{"id":"T170","span":{"begin":85,"end":89},"obj":"Disease"},{"id":"T171","span":{"begin":165,"end":176},"obj":"Disease"}],"attributes":[{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A170","pred":"mondo_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A171","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0003783"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T169","span":{"begin":106,"end":107},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T170","span":{"begin":222,"end":227},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T171","span":{"begin":237,"end":246},"obj":"http://purl.obolibrary.org/obo/CL_0000576"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T78","span":{"begin":140,"end":147},"obj":"Chemical"},{"id":"T79","span":{"begin":293,"end":295},"obj":"Chemical"}],"attributes":[{"id":"A78","pred":"chebi_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A79","pred":"chebi_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A80","pred":"chebi_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T27","span":{"begin":140,"end":160},"obj":"http://purl.obolibrary.org/obo/GO_0019882"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-sentences","denotations":[{"id":"T140","span":{"begin":0,"end":298},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T69","span":{"begin":65,"end":74},"obj":"Phenotype"},{"id":"T70","span":{"begin":165,"end":176},"obj":"Phenotype"}],"attributes":[{"id":"A69","pred":"hp_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A70","pred":"hp_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/HP_0001888"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T501","span":{"begin":50,"end":53},"obj":"PR:000015613"},{"id":"T502","span":{"begin":85,"end":95},"obj":"SP_7"},{"id":"T503","span":{"begin":140,"end":147},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T504","span":{"begin":213,"end":227},"obj":"CL:0000542"},{"id":"T505","span":{"begin":237,"end":246},"obj":"CL:0000576"},{"id":"T506","span":{"begin":283,"end":287},"obj":"PR:000000134"},{"id":"T507","span":{"begin":287,"end":288},"obj":"PR:000000134;GO:1990774"},{"id":"T508","span":{"begin":293,"end":297},"obj":"PR:000001393"},{"id":"T593","span":{"begin":6,"end":10},"obj":"PR:000001393"},{"id":"T594","span":{"begin":90,"end":95},"obj":"NCBITaxon:10239"},{"id":"T595","span":{"begin":103,"end":113},"obj":"SP_7"},{"id":"T596","span":{"begin":121,"end":126},"obj":"UBERON:0001977"},{"id":"T597","span":{"begin":138,"end":143},"obj":"PR:000000134"},{"id":"T598","span":{"begin":145,"end":149},"obj":"PR:000001393"},{"id":"T599","span":{"begin":190,"end":200},"obj":"SP_7"},{"id":"T600","span":{"begin":227,"end":232},"obj":"UBERON:0002405;GO:0006955"},{"id":"T601","span":{"begin":233,"end":243},"obj":"GO:0006955"},{"id":"T602","span":{"begin":259,"end":272},"obj":"GO:0065007"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}

{"project":"LitCovid-PubTator","denotations":[{"id":"777","span":{"begin":283,"end":288},"obj":"Gene"},{"id":"778","span":{"begin":293,"end":297},"obj":"Gene"},{"id":"788","span":{"begin":85,"end":95},"obj":"Species"},{"id":"794","span":{"begin":50,"end":74},"obj":"Disease"},{"id":"795","span":{"begin":165,"end":176},"obj":"Disease"}],"attributes":[{"id":"A777","pred":"tao:has_database_id","subj":"777","obj":"Gene:7124"},{"id":"A778","pred":"tao:has_database_id","subj":"778","obj":"Gene:3569"},{"id":"A788","pred":"tao:has_database_id","subj":"788","obj":"Tax:2697049"},{"id":"A794","pred":"tao:has_database_id","subj":"794","obj":"MESH:C538353"},{"id":"A795","pred":"tao:has_database_id","subj":"795","obj":"MESH:D008231"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This generated the hypothesis that in the case of SRF-aggravated pneumonia caused by SARS-CoV-2, there is a unique combination of defective antigen presentation and lymphopenia that leads to defective function of lymphoid cells, whereas monocytes remain potent for the production of TNF-α and IL-6."}