PMC:7172841 / 16171-16909 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7172841","sourcedb":"PMC","sourceid":"7172841","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7172841","text":"Moderate Derangement of Circulating Immunoglobulins in Pneumonia Caused by SARS-CoV-2\nSerum amounts of IgG subclasses (A–D), IgM (E), and IgA (F) of patients with CAP caused by SARS-CoV-2 are shown. Patients are classified into three states of immune activation: intermediate, dysregulation, and MAS. Findings are compared with those in patients with bacterial CAP, who are classified into three states of immune activation: intermediate, immunoparalysis, and MAS.\nBars in each graphic represent mean values and standard errors. Only statistically significant comparisons are indicated by the arrows; ∗p \u003c 0.05; ∗∗p \u003c 0.0001; ∗∗∗p \u003c 0.0001. Comparisons were done by the Mann-Whitney U test followed by correction for multiple comparisons.","divisions":[{"label":"p","span":{"begin":0,"end":85}},{"label":"p","span":{"begin":86,"end":464}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T99","span":{"begin":36,"end":51},"obj":"Body_part"},{"id":"T100","span":{"begin":86,"end":91},"obj":"Body_part"},{"id":"T101","span":{"begin":103,"end":106},"obj":"Body_part"},{"id":"T102","span":{"begin":125,"end":128},"obj":"Body_part"},{"id":"T103","span":{"begin":138,"end":141},"obj":"Body_part"}],"attributes":[{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma63083"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma62873"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma62874"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T102","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T103","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T12","span":{"begin":86,"end":91},"obj":"Body_part"}],"attributes":[{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"subj":"T12","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T154","span":{"begin":55,"end":64},"obj":"Disease"},{"id":"T155","span":{"begin":75,"end":83},"obj":"Disease"},{"id":"T156","span":{"begin":75,"end":79},"obj":"Disease"},{"id":"T157","span":{"begin":177,"end":185},"obj":"Disease"},{"id":"T158","span":{"begin":177,"end":181},"obj":"Disease"},{"id":"T159","span":{"begin":296,"end":299},"obj":"Disease"},{"id":"T160","span":{"begin":460,"end":463},"obj":"Disease"}],"attributes":[{"id":"A154","pred":"mondo_id","subj":"T154","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A155","pred":"mondo_id","subj":"T155","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A156","pred":"mondo_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A157","pred":"mondo_id","subj":"T157","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A158","pred":"mondo_id","subj":"T158","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A159","pred":"mondo_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A160","pred":"mondo_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"subj":"T154","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T155","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T156","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T157","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T158","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T159","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T160","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T159","span":{"begin":119,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T160","span":{"begin":251,"end":261},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T161","span":{"begin":413,"end":423},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T162","span":{"begin":685,"end":689},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"attributes":[{"subj":"T159","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T160","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T161","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T162","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T127","span":{"begin":86,"end":198},"obj":"Sentence"},{"id":"T128","span":{"begin":199,"end":300},"obj":"Sentence"},{"id":"T129","span":{"begin":301,"end":464},"obj":"Sentence"},{"id":"T130","span":{"begin":465,"end":528},"obj":"Sentence"},{"id":"T131","span":{"begin":529,"end":640},"obj":"Sentence"},{"id":"T132","span":{"begin":641,"end":738},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T127","pred":"source","obj":"LitCovid-sentences"},{"subj":"T128","pred":"source","obj":"LitCovid-sentences"},{"subj":"T129","pred":"source","obj":"LitCovid-sentences"},{"subj":"T130","pred":"source","obj":"LitCovid-sentences"},{"subj":"T131","pred":"source","obj":"LitCovid-sentences"},{"subj":"T132","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T63","span":{"begin":55,"end":64},"obj":"Phenotype"}],"attributes":[{"id":"A63","pred":"hp_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T452","span":{"begin":36,"end":51},"obj":"GO:0019814"},{"id":"T453","span":{"begin":75,"end":91},"obj":"SP_7"},{"id":"T454","span":{"begin":103,"end":106},"obj":"GO:0071735"},{"id":"T455","span":{"begin":125,"end":128},"obj":"GO:0071735"},{"id":"T456","span":{"begin":177,"end":187},"obj":"SP_7"},{"id":"T457","span":{"begin":244,"end":250},"obj":"UBERON:0002405;GO:0006955"},{"id":"T458","span":{"begin":251,"end":261},"obj":"GO:0006955"},{"id":"T459","span":{"begin":277,"end":290},"obj":"GO:0065007"},{"id":"T460","span":{"begin":351,"end":360},"obj":"NCBITaxon:2"},{"id":"T461","span":{"begin":406,"end":412},"obj":"UBERON:0002405;GO:0006955"},{"id":"T462","span":{"begin":413,"end":423},"obj":"GO:0042110"},{"id":"T3948","span":{"begin":42,"end":47},"obj":"NCBITaxon:10239"},{"id":"T69859","span":{"begin":55,"end":65},"obj":"SP_7"},{"id":"T47500","span":{"begin":72,"end":77},"obj":"UBERON:0001977"},{"id":"T74511","span":{"begin":89,"end":94},"obj":"PR:000000134"},{"id":"T65601","span":{"begin":96,"end":100},"obj":"PR:000001393"},{"id":"T78897","span":{"begin":141,"end":151},"obj":"SP_7"},{"id":"T58470","span":{"begin":178,"end":183},"obj":"UBERON:0002405;GO:0006955"},{"id":"T10607","span":{"begin":184,"end":194},"obj":"GO:0006955"},{"id":"T41441","span":{"begin":210,"end":223},"obj":"GO:0065007"},{"id":"T555","span":{"begin":549,"end":554},"obj":"UBERON:0002405"},{"id":"T556","span":{"begin":592,"end":602},"obj":"SP_7"},{"id":"T557","span":{"begin":607,"end":620},"obj":"GO:1990774"},{"id":"T558","span":{"begin":621,"end":626},"obj":"GO:1990774;PR:000000134"},{"id":"T559","span":{"begin":668,"end":677},"obj":"NCBITaxon:2"},{"id":"T560","span":{"begin":721,"end":726},"obj":"GO:0006955;UBERON:0002405"},{"id":"T561","span":{"begin":727,"end":737},"obj":"GO:0042110"}],"attributes":[{"subj":"T452","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T453","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T454","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T455","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T456","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T457","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T458","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T459","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T460","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T461","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T462","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T3948","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T69859","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T47500","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T74511","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T65601","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T78897","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T58470","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T10607","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T41441","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T555","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T556","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T557","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T558","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T559","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T560","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T561","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"627","span":{"begin":55,"end":64},"obj":"Disease"},{"id":"633","span":{"begin":149,"end":157},"obj":"Species"},{"id":"634","span":{"begin":177,"end":187},"obj":"Species"},{"id":"635","span":{"begin":199,"end":207},"obj":"Species"},{"id":"636","span":{"begin":337,"end":345},"obj":"Species"},{"id":"637","span":{"begin":439,"end":454},"obj":"Disease"}],"attributes":[{"id":"A627","pred":"tao:has_database_id","subj":"627","obj":"MESH:D011014"},{"id":"A633","pred":"tao:has_database_id","subj":"633","obj":"Tax:9606"},{"id":"A634","pred":"tao:has_database_id","subj":"634","obj":"Tax:2697049"},{"id":"A635","pred":"tao:has_database_id","subj":"635","obj":"Tax:9606"},{"id":"A636","pred":"tao:has_database_id","subj":"636","obj":"Tax:9606"},{"subj":"627","pred":"source","obj":"LitCovid-PubTator"},{"subj":"633","pred":"source","obj":"LitCovid-PubTator"},{"subj":"634","pred":"source","obj":"LitCovid-PubTator"},{"subj":"635","pred":"source","obj":"LitCovid-PubTator"},{"subj":"636","pred":"source","obj":"LitCovid-PubTator"},{"subj":"637","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93bf","default":true},{"id":"LitCovid-PD-UBERON","color":"#93d9ec"},{"id":"LitCovid-PD-MONDO","color":"#ece493"},{"id":"LitCovid-PD-CLO","color":"#ca93ec"},{"id":"LitCovid-sentences","color":"#93ecb0"},{"id":"LitCovid-PD-HP","color":"#ec9693"},{"id":"LitCovid-PMC-OGER-BB","color":"#93a9ec"},{"id":"LitCovid-PubTator","color":"#c3ec93"}]}]}}