PMC:7172841 / 10481-13310 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7172841","sourcedb":"PMC","sourceid":"7172841","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7172841","text":"Immunoparalysis of sepsis is characterized by significant decrease of the number of HLA-DR molecules on CD14 monocytes. This also happens in immune dysregulation caused by SARS-CoV-2 (Figures 1A and 1B). Although patients with bacterial-CAP-associated MAS also have decreased HLA-DR molecules on CD14 monocytes, their circulating ferritin is significantly higher than normal. This is a feature found only in a few patients with SARS-CoV-2 and MAS (Figure 1C). The absence of traits of MAS among cases of SARS-CoV-2 with immune dysregulation is further proven by the low scores of hemophagocytosis (HS). HScore is proposed as a classification tool for secondary MAS, and values more than 169 are highly diagnostic (Fardet et al., 2014). Seven patients with SARS-CoV-2 had HS above this cut-off, and all were properly classified by using ferritin (Figure 1D). Among patients with bacterial CAP at an intermediate immune state, the number of molecules of HLA-DR on their CD14 monocytes was lower than in healthy patients. However, patients with pneumonia caused by SARS-CoV-2 at an intermediate immune state maintained their number of molecules of HLA-DR on CD14 monocytes much closer to the healthy condition. When this number suddenly dropped, SRF supervened (Figures 1A and 1B). Moreover, the absolute counts of neutrophils and monocytes were higher among patients with immune dysregulation than patients with MAS (Figures 1E and 1F).\nFigure 1 Characteristics of Immune Dysregulation of COVID-19\n(A) Absolute numbers of the molecules of the human leukocyte antigen (mHLA-DR) on CD14 monocytes. Patients with bacterial CAP and CAP caused by SARS-CoV-2 are classified into three states of immune activation: intermediate, immunoparalysis for bacterial CAP and dysregulation for COVID-19, and MAS.\n(B) Mean fluorescence intensity (MFI) of HLA-DR on CD14 monocytes of healthy volunteers and of patients with CAP caused by SARS-CoV-2 classified according to their state of immune activation.\n(C) Ferritin concentrations in the serum of patients with bacterial CAP and sepsis and CAP caused by SAR-CoV-2 according to their state of immune activation.\n(D) Hemophagocytosis score among patients with CAP caused by SARS-CoV-2 classified according to their state of immune activation.\n(E) Absolute neutrophil counts among patients with CAP caused by SARS-CoV-2 classified according to their state of immune activation.\n(F) Absolute monocyte counts among patients with CAP caused by SARS-CoV-2 classified according to their state of immune activation.\nBars in each graphic represent mean values and standard errors. Statistical comparisons are indicated by the arrows; ns: non-significant; ∗p \u003c 0.05; ∗∗p \u003c 0.01; ∗∗∗p \u003c 0.001; ∗∗∗∗p \u003c 0.0001. Comparisons were done by the Mann-Whitney U test followed by correction for multiple comparisons.","divisions":[{"label":"label","span":{"begin":1435,"end":1443}},{"label":"p","span":{"begin":1444,"end":1495}},{"label":"p","span":{"begin":1496,"end":1794}},{"label":"p","span":{"begin":1795,"end":1986}},{"label":"p","span":{"begin":1987,"end":2144}},{"label":"p","span":{"begin":2145,"end":2274}},{"label":"p","span":{"begin":2275,"end":2408}},{"label":"p","span":{"begin":2409,"end":2540}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T44","span":{"begin":84,"end":87},"obj":"Body_part"},{"id":"T45","span":{"begin":109,"end":118},"obj":"Body_part"},{"id":"T46","span":{"begin":276,"end":279},"obj":"Body_part"},{"id":"T47","span":{"begin":301,"end":310},"obj":"Body_part"},{"id":"T48","span":{"begin":952,"end":955},"obj":"Body_part"},{"id":"T49","span":{"begin":973,"end":982},"obj":"Body_part"},{"id":"T50","span":{"begin":1145,"end":1148},"obj":"Body_part"},{"id":"T51","span":{"begin":1160,"end":1169},"obj":"Body_part"},{"id":"T52","span":{"begin":1312,"end":1323},"obj":"Body_part"},{"id":"T53","span":{"begin":1328,"end":1337},"obj":"Body_part"},{"id":"T54","span":{"begin":1547,"end":1556},"obj":"Body_part"},{"id":"T55","span":{"begin":1583,"end":1592},"obj":"Body_part"},{"id":"T56","span":{"begin":1836,"end":1839},"obj":"Body_part"},{"id":"T57","span":{"begin":1851,"end":1860},"obj":"Body_part"},{"id":"T58","span":{"begin":2022,"end":2027},"obj":"Body_part"},{"id":"T59","span":{"begin":2288,"end":2298},"obj":"Body_part"},{"id":"T60","span":{"begin":2422,"end":2430},"obj":"Body_part"}],"attributes":[{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma84795"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma63083"},{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma62864"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T56","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T57","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T10","span":{"begin":2022,"end":2027},"obj":"Body_part"}],"attributes":[{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T103","span":{"begin":172,"end":180},"obj":"Disease"},{"id":"T104","span":{"begin":172,"end":176},"obj":"Disease"},{"id":"T105","span":{"begin":252,"end":255},"obj":"Disease"},{"id":"T106","span":{"begin":428,"end":436},"obj":"Disease"},{"id":"T107","span":{"begin":428,"end":432},"obj":"Disease"},{"id":"T108","span":{"begin":443,"end":446},"obj":"Disease"},{"id":"T109","span":{"begin":485,"end":488},"obj":"Disease"},{"id":"T110","span":{"begin":504,"end":512},"obj":"Disease"},{"id":"T111","span":{"begin":504,"end":508},"obj":"Disease"},{"id":"T112","span":{"begin":661,"end":664},"obj":"Disease"},{"id":"T113","span":{"begin":756,"end":764},"obj":"Disease"},{"id":"T114","span":{"begin":756,"end":760},"obj":"Disease"},{"id":"T115","span":{"begin":1042,"end":1051},"obj":"Disease"},{"id":"T116","span":{"begin":1062,"end":1070},"obj":"Disease"},{"id":"T117","span":{"begin":1062,"end":1066},"obj":"Disease"},{"id":"T118","span":{"begin":1410,"end":1413},"obj":"Disease"},{"id":"T119","span":{"begin":1487,"end":1495},"obj":"Disease"},{"id":"T120","span":{"begin":1640,"end":1648},"obj":"Disease"},{"id":"T121","span":{"begin":1640,"end":1644},"obj":"Disease"},{"id":"T122","span":{"begin":1776,"end":1784},"obj":"Disease"},{"id":"T123","span":{"begin":1790,"end":1793},"obj":"Disease"},{"id":"T124","span":{"begin":1918,"end":1926},"obj":"Disease"},{"id":"T125","span":{"begin":1918,"end":1922},"obj":"Disease"},{"id":"T126","span":{"begin":2206,"end":2214},"obj":"Disease"},{"id":"T127","span":{"begin":2206,"end":2210},"obj":"Disease"},{"id":"T128","span":{"begin":2340,"end":2348},"obj":"Disease"},{"id":"T129","span":{"begin":2340,"end":2344},"obj":"Disease"},{"id":"T130","span":{"begin":2472,"end":2480},"obj":"Disease"},{"id":"T131","span":{"begin":2472,"end":2476},"obj":"Disease"}],"attributes":[{"id":"A103","pred":"mondo_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A104","pred":"mondo_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A105","pred":"mondo_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A106","pred":"mondo_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A107","pred":"mondo_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A108","pred":"mondo_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A109","pred":"mondo_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A110","pred":"mondo_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A111","pred":"mondo_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A112","pred":"mondo_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A113","pred":"mondo_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A114","pred":"mondo_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A115","pred":"mondo_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A116","pred":"mondo_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A117","pred":"mondo_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A119","pred":"mondo_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A120","pred":"mondo_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A121","pred":"mondo_id","subj":"T121","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A122","pred":"mondo_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A123","pred":"mondo_id","subj":"T123","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A124","pred":"mondo_id","subj":"T124","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A125","pred":"mondo_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A126","pred":"mondo_id","subj":"T126","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A127","pred":"mondo_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A128","pred":"mondo_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A129","pred":"mondo_id","subj":"T129","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A130","pred":"mondo_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A131","pred":"mondo_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T103","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T104","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T105","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T106","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T108","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T109","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T116","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T117","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T118","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T119","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T120","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T121","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T122","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T123","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T124","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T125","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T126","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T127","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T128","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T129","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T130","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T131","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T63","span":{"begin":109,"end":118},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T64","span":{"begin":301,"end":310},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T65","span":{"begin":384,"end":385},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T66","span":{"begin":408,"end":409},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T67","span":{"begin":625,"end":626},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T68","span":{"begin":973,"end":982},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T69","span":{"begin":1160,"end":1169},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T70","span":{"begin":1328,"end":1337},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T71","span":{"begin":1497,"end":1498},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T72","span":{"begin":1541,"end":1546},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T73","span":{"begin":1583,"end":1592},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T74","span":{"begin":1694,"end":1704},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T75","span":{"begin":1796,"end":1797},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T76","span":{"begin":1851,"end":1860},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T77","span":{"begin":1975,"end":1985},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T78","span":{"begin":2133,"end":2143},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T79","span":{"begin":2263,"end":2273},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T80","span":{"begin":2397,"end":2407},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T81","span":{"begin":2422,"end":2430},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T82","span":{"begin":2529,"end":2539},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T83","span":{"begin":2776,"end":2780},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"attributes":[{"subj":"T63","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T47","span":{"begin":88,"end":90},"obj":"Chemical"},{"id":"T48","span":{"begin":91,"end":100},"obj":"Chemical"},{"id":"T49","span":{"begin":280,"end":282},"obj":"Chemical"},{"id":"T50","span":{"begin":283,"end":292},"obj":"Chemical"},{"id":"T51","span":{"begin":598,"end":600},"obj":"Chemical"},{"id":"T52","span":{"begin":771,"end":773},"obj":"Chemical"},{"id":"T53","span":{"begin":939,"end":948},"obj":"Chemical"},{"id":"T54","span":{"begin":956,"end":958},"obj":"Chemical"},{"id":"T55","span":{"begin":1132,"end":1141},"obj":"Chemical"},{"id":"T56","span":{"begin":1149,"end":1151},"obj":"Chemical"},{"id":"T57","span":{"begin":1524,"end":1533},"obj":"Chemical"},{"id":"T58","span":{"begin":1557,"end":1564},"obj":"Chemical"},{"id":"T59","span":{"begin":1571,"end":1573},"obj":"Chemical"},{"id":"T60","span":{"begin":1840,"end":1842},"obj":"Chemical"},{"id":"T61","span":{"begin":1991,"end":1999},"obj":"Chemical"}],"attributes":[{"id":"A47","pred":"chebi_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A48","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A49","pred":"chebi_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A50","pred":"chebi_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A51","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_74056"},{"id":"A52","pred":"chebi_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_74056"},{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A54","pred":"chebi_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A55","pred":"chebi_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A56","pred":"chebi_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A57","pred":"chebi_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A58","pred":"chebi_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/CHEBI_59132"},{"id":"A59","pred":"chebi_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A60","pred":"chebi_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/CHEBI_73445"},{"id":"A61","pred":"chebi_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_82594"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T56","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T57","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T86","span":{"begin":0,"end":119},"obj":"Sentence"},{"id":"T87","span":{"begin":120,"end":203},"obj":"Sentence"},{"id":"T88","span":{"begin":204,"end":375},"obj":"Sentence"},{"id":"T89","span":{"begin":376,"end":459},"obj":"Sentence"},{"id":"T90","span":{"begin":460,"end":602},"obj":"Sentence"},{"id":"T91","span":{"begin":603,"end":735},"obj":"Sentence"},{"id":"T92","span":{"begin":736,"end":857},"obj":"Sentence"},{"id":"T93","span":{"begin":858,"end":1018},"obj":"Sentence"},{"id":"T94","span":{"begin":1019,"end":1207},"obj":"Sentence"},{"id":"T95","span":{"begin":1208,"end":1278},"obj":"Sentence"},{"id":"T96","span":{"begin":1279,"end":1434},"obj":"Sentence"},{"id":"T97","span":{"begin":1435,"end":1495},"obj":"Sentence"},{"id":"T98","span":{"begin":1496,"end":1593},"obj":"Sentence"},{"id":"T99","span":{"begin":1594,"end":1794},"obj":"Sentence"},{"id":"T100","span":{"begin":1795,"end":1986},"obj":"Sentence"},{"id":"T101","span":{"begin":1987,"end":2144},"obj":"Sentence"},{"id":"T102","span":{"begin":2145,"end":2274},"obj":"Sentence"},{"id":"T103","span":{"begin":2275,"end":2408},"obj":"Sentence"},{"id":"T104","span":{"begin":2409,"end":2540},"obj":"Sentence"},{"id":"T105","span":{"begin":2541,"end":2604},"obj":"Sentence"},{"id":"T106","span":{"begin":2605,"end":2731},"obj":"Sentence"},{"id":"T107","span":{"begin":2732,"end":2829},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T86","pred":"source","obj":"LitCovid-sentences"},{"subj":"T87","pred":"source","obj":"LitCovid-sentences"},{"subj":"T88","pred":"source","obj":"LitCovid-sentences"},{"subj":"T89","pred":"source","obj":"LitCovid-sentences"},{"subj":"T90","pred":"source","obj":"LitCovid-sentences"},{"subj":"T91","pred":"source","obj":"LitCovid-sentences"},{"subj":"T92","pred":"source","obj":"LitCovid-sentences"},{"subj":"T93","pred":"source","obj":"LitCovid-sentences"},{"subj":"T94","pred":"source","obj":"LitCovid-sentences"},{"subj":"T95","pred":"source","obj":"LitCovid-sentences"},{"subj":"T96","pred":"source","obj":"LitCovid-sentences"},{"subj":"T97","pred":"source","obj":"LitCovid-sentences"},{"subj":"T98","pred":"source","obj":"LitCovid-sentences"},{"subj":"T99","pred":"source","obj":"LitCovid-sentences"},{"subj":"T100","pred":"source","obj":"LitCovid-sentences"},{"subj":"T101","pred":"source","obj":"LitCovid-sentences"},{"subj":"T102","pred":"source","obj":"LitCovid-sentences"},{"subj":"T103","pred":"source","obj":"LitCovid-sentences"},{"subj":"T104","pred":"source","obj":"LitCovid-sentences"},{"subj":"T105","pred":"source","obj":"LitCovid-sentences"},{"subj":"T106","pred":"source","obj":"LitCovid-sentences"},{"subj":"T107","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T48","span":{"begin":19,"end":25},"obj":"Phenotype"},{"id":"T49","span":{"begin":141,"end":161},"obj":"Phenotype"},{"id":"T50","span":{"begin":520,"end":540},"obj":"Phenotype"},{"id":"T51","span":{"begin":580,"end":596},"obj":"Phenotype"},{"id":"T52","span":{"begin":598,"end":600},"obj":"Phenotype"},{"id":"T53","span":{"begin":771,"end":773},"obj":"Phenotype"},{"id":"T54","span":{"begin":1042,"end":1051},"obj":"Phenotype"},{"id":"T55","span":{"begin":1370,"end":1390},"obj":"Phenotype"},{"id":"T56","span":{"begin":1463,"end":1483},"obj":"Phenotype"},{"id":"T57","span":{"begin":2063,"end":2069},"obj":"Phenotype"},{"id":"T58","span":{"begin":2149,"end":2165},"obj":"Phenotype"}],"attributes":[{"id":"A48","pred":"hp_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/HP_0100806"},{"id":"A49","pred":"hp_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/HP_0002958"},{"id":"A50","pred":"hp_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/HP_0002958"},{"id":"A51","pred":"hp_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/HP_0012156"},{"id":"A52","pred":"hp_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/HP_0012156"},{"id":"A53","pred":"hp_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/HP_0012156"},{"id":"A54","pred":"hp_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A55","pred":"hp_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/HP_0002958"},{"id":"A56","pred":"hp_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/HP_0002958"},{"id":"A57","pred":"hp_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/HP_0100806"},{"id":"A58","pred":"hp_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/HP_0012156"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T56","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T57","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T186","span":{"begin":84,"end":87},"obj":"PR:000029150"},{"id":"T187","span":{"begin":91,"end":100},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T188","span":{"begin":104,"end":108},"obj":"PR:000001889"},{"id":"T189","span":{"begin":109,"end":118},"obj":"CL:0000576"},{"id":"T190","span":{"begin":141,"end":147},"obj":"UBERON:0002405;GO:0045087"},{"id":"T191","span":{"begin":148,"end":161},"obj":"GO:0006955"},{"id":"T192","span":{"begin":172,"end":182},"obj":"SP_7"},{"id":"T193","span":{"begin":227,"end":236},"obj":"NCBITaxon:2"},{"id":"T194","span":{"begin":276,"end":279},"obj":"PR:000029150"},{"id":"T195","span":{"begin":283,"end":292},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T196","span":{"begin":296,"end":300},"obj":"PR:000001889"},{"id":"T197","span":{"begin":301,"end":310},"obj":"CL:0000576"},{"id":"T198","span":{"begin":428,"end":438},"obj":"SP_7"},{"id":"T199","span":{"begin":504,"end":514},"obj":"SP_7"},{"id":"T200","span":{"begin":520,"end":526},"obj":"UBERON:0002405"},{"id":"T201","span":{"begin":527,"end":540},"obj":"GO:0065007"},{"id":"T202","span":{"begin":580,"end":596},"obj":"GO:0030097"},{"id":"T203","span":{"begin":756,"end":766},"obj":"SP_7"},{"id":"T204","span":{"begin":878,"end":887},"obj":"NCBITaxon:2"},{"id":"T205","span":{"begin":911,"end":917},"obj":"UBERON:0002405"},{"id":"T206","span":{"begin":939,"end":948},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T207","span":{"begin":952,"end":955},"obj":"PR:000029150"},{"id":"T208","span":{"begin":968,"end":972},"obj":"PR:000001889"},{"id":"T209","span":{"begin":973,"end":982},"obj":"CL:0000576"},{"id":"T210","span":{"begin":1062,"end":1072},"obj":"SP_7"},{"id":"T211","span":{"begin":1092,"end":1098},"obj":"UBERON:0002405"},{"id":"T212","span":{"begin":1132,"end":1141},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T213","span":{"begin":1145,"end":1148},"obj":"PR:000029150"},{"id":"T214","span":{"begin":1155,"end":1159},"obj":"PR:000001889"},{"id":"T215","span":{"begin":1160,"end":1169},"obj":"CL:0000576"},{"id":"T216","span":{"begin":1312,"end":1323},"obj":"CL:0000775"},{"id":"T217","span":{"begin":1328,"end":1337},"obj":"CL:0000576"},{"id":"T218","span":{"begin":1370,"end":1376},"obj":"UBERON:0002405"},{"id":"T219","span":{"begin":1377,"end":1390},"obj":"GO:0065007"},{"id":"T220","span":{"begin":1487,"end":1495},"obj":"SP_7"},{"id":"T221","span":{"begin":1524,"end":1533},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T222","span":{"begin":1541,"end":1546},"obj":"SP_6;NCBITaxon:9606"},{"id":"T223","span":{"begin":1547,"end":1556},"obj":"CL:0000738"},{"id":"T224","span":{"begin":1557,"end":1564},"obj":"CHEBI:59132;CHEBI:59132"},{"id":"T225","span":{"begin":1578,"end":1582},"obj":"PR:000001889"},{"id":"T226","span":{"begin":1583,"end":1592},"obj":"CL:0000576"},{"id":"T227","span":{"begin":1608,"end":1617},"obj":"NCBITaxon:2"},{"id":"T228","span":{"begin":1640,"end":1650},"obj":"SP_7"},{"id":"T229","span":{"begin":1687,"end":1693},"obj":"UBERON:0002405;GO:0006955"},{"id":"T230","span":{"begin":1694,"end":1704},"obj":"GO:0042110"},{"id":"T231","span":{"begin":1740,"end":1749},"obj":"NCBITaxon:2"},{"id":"T232","span":{"begin":1758,"end":1771},"obj":"GO:0065007"},{"id":"T233","span":{"begin":1776,"end":1784},"obj":"SP_7"},{"id":"T234","span":{"begin":1836,"end":1839},"obj":"PR:000029150"},{"id":"T235","span":{"begin":1846,"end":1850},"obj":"PR:000001889"},{"id":"T236","span":{"begin":1851,"end":1860},"obj":"CL:0000576"},{"id":"T237","span":{"begin":1918,"end":1928},"obj":"SP_7"},{"id":"T238","span":{"begin":1968,"end":1974},"obj":"UBERON:0002405;GO:0006955"},{"id":"T239","span":{"begin":1975,"end":1985},"obj":"GO:0006955"},{"id":"T240","span":{"begin":1991,"end":1999},"obj":"CHEBI:82594;CHEBI:82594"},{"id":"T241","span":{"begin":2022,"end":2027},"obj":"UBERON:0001977"},{"id":"T242","span":{"begin":2045,"end":2054},"obj":"NCBITaxon:2"},{"id":"T243","span":{"begin":2149,"end":2165},"obj":"GO:0006909"},{"id":"T244","span":{"begin":2206,"end":2216},"obj":"SP_7"},{"id":"T245","span":{"begin":2256,"end":2262},"obj":"UBERON:0002405;GO:0006955"},{"id":"T246","span":{"begin":2263,"end":2273},"obj":"GO:0006955"},{"id":"T247","span":{"begin":2288,"end":2298},"obj":"CL:0000775"},{"id":"T248","span":{"begin":2340,"end":2350},"obj":"SP_7"},{"id":"T249","span":{"begin":2390,"end":2396},"obj":"UBERON:0002405;GO:0006955"},{"id":"T250","span":{"begin":2397,"end":2407},"obj":"GO:0006955"},{"id":"T251","span":{"begin":2422,"end":2430},"obj":"CL:0000576"},{"id":"T252","span":{"begin":2472,"end":2482},"obj":"SP_7"},{"id":"T253","span":{"begin":2522,"end":2528},"obj":"UBERON:0002405;GO:0006955"},{"id":"T254","span":{"begin":2529,"end":2539},"obj":"GO:0006955"},{"id":"T400","span":{"begin":8,"end":12},"obj":"PR:000001002"},{"id":"T401","span":{"begin":13,"end":17},"obj":"PR:000001006"},{"id":"T402","span":{"begin":19,"end":32},"obj":"CL:0000542"},{"id":"T403","span":{"begin":105,"end":114},"obj":"NCBITaxon:7719"},{"id":"T404","span":{"begin":115,"end":120},"obj":"NCBITaxon:10239"},{"id":"T405","span":{"begin":155,"end":163},"obj":"SP_7"},{"id":"T406","span":{"begin":179,"end":187},"obj":"SP_7"},{"id":"T407","span":{"begin":224,"end":229},"obj":"UBERON:0002405;GO:0006955"},{"id":"T408","span":{"begin":230,"end":240},"obj":"GO:0042110"},{"id":"T409","span":{"begin":256,"end":269},"obj":"GO:0065007"},{"id":"T410","span":{"begin":309,"end":312},"obj":"PR:000001004"},{"id":"T411","span":{"begin":313,"end":317},"obj":"PR:000001006"},{"id":"T412","span":{"begin":319,"end":330},"obj":"CL:0000542"},{"id":"T413","span":{"begin":344,"end":348},"obj":"PR:000001006"},{"id":"T414","span":{"begin":350,"end":361},"obj":"CL:0000542"},{"id":"T415","span":{"begin":371,"end":375},"obj":"PR:000001483"},{"id":"T416","span":{"begin":376,"end":380},"obj":"PR:000001024"},{"id":"T417","span":{"begin":381,"end":385},"obj":"PR:000001006"},{"id":"T418","span":{"begin":387,"end":398},"obj":"CL:0000542"},{"id":"T419","span":{"begin":408,"end":412},"obj":"PR:000001483"},{"id":"T420","span":{"begin":413,"end":417},"obj":"PR:000001024"},{"id":"T421","span":{"begin":418,"end":422},"obj":"PR:000001006"},{"id":"T422","span":{"begin":439,"end":443},"obj":"PR:000001002"},{"id":"T423","span":{"begin":444,"end":448},"obj":"PR:000001006"},{"id":"T424","span":{"begin":450,"end":461},"obj":"CL:0000542"},{"id":"T425","span":{"begin":493,"end":503},"obj":"UBERON:0001004"},{"id":"T426","span":{"begin":566,"end":575},"obj":"NCBITaxon:7719"},{"id":"T427","span":{"begin":576,"end":581},"obj":"NCBITaxon:10239"},{"id":"T428","span":{"begin":586,"end":594},"obj":"SP_7"},{"id":"T429","span":{"begin":600,"end":602},"obj":"PR:000001092"},{"id":"T430","span":{"begin":602,"end":605},"obj":"PR:000001092;GO:1990774"},{"id":"T431","span":{"begin":660,"end":667},"obj":"NCBITaxon:5478"},{"id":"T432","span":{"begin":668,"end":676},"obj":"NCBITaxon:8296"},{"id":"T98490","span":{"begin":1007,"end":1011},"obj":"PR:000001002"},{"id":"T81900","span":{"begin":1012,"end":1016},"obj":"PR:000001006"},{"id":"T4731","span":{"begin":1018,"end":1029},"obj":"CL:0000542"},{"id":"T98663","span":{"begin":1033,"end":1043},"obj":"GO:0006412"},{"id":"T87532","span":{"begin":1047,"end":1052},"obj":"UBERON:0001977"},{"id":"T7919","span":{"begin":1053,"end":1067},"obj":"GO:0019814"},{"id":"T90937","span":{"begin":1092,"end":1097},"obj":"GO:0071735"},{"id":"T37745","span":{"begin":1127,"end":1133},"obj":"UBERON:0001969"},{"id":"T25561","span":{"begin":1137,"end":1145},"obj":"SP_7"},{"id":"T59339","span":{"begin":1178,"end":1187},"obj":"NCBITaxon:2"},{"id":"T49058","span":{"begin":1218,"end":1222},"obj":"GO:0071735"},{"id":"T11188","span":{"begin":1227,"end":1230},"obj":"GO:0071735"},{"id":"T71125","span":{"begin":1251,"end":1260},"obj":"NCBITaxon:2"},{"id":"T12356","span":{"begin":1329,"end":1332},"obj":"GO:0071735"},{"id":"T4248","span":{"begin":1372,"end":1378},"obj":"UBERON:0002405"},{"id":"T79682","span":{"begin":1402,"end":1407},"obj":"UBERON:0002405"},{"id":"T72845","span":{"begin":1408,"end":1421},"obj":"GO:0065007"},{"id":"T54752","span":{"begin":1432,"end":1435},"obj":"GO:0071735"},{"id":"T81988","span":{"begin":1467,"end":1472},"obj":"UBERON:0002405"},{"id":"T92925","span":{"begin":1524,"end":1538},"obj":"GO:0019814"},{"id":"T35504","span":{"begin":1562,"end":1577},"obj":"SP_7"},{"id":"T59865","span":{"begin":1589,"end":1592},"obj":"GO:0071735"},{"id":"T4129","span":{"begin":1611,"end":1614},"obj":"GO:0071735"},{"id":"T21016","span":{"begin":1663,"end":1673},"obj":"SP_7"},{"id":"T96566","span":{"begin":1732,"end":1737},"obj":"UBERON:0002405;GO:0006955"},{"id":"T19391","span":{"begin":1738,"end":1748},"obj":"GO:0006955"},{"id":"T65950","span":{"begin":1764,"end":1777},"obj":"GO:0065007"},{"id":"T84161","span":{"begin":1838,"end":1847},"obj":"NCBITaxon:2"},{"id":"T35511","span":{"begin":1893,"end":1898},"obj":"UBERON:0002405;GO:0006955"},{"id":"T7097","span":{"begin":1899,"end":1909},"obj":"GO:0042110"},{"id":"T463","span":{"begin":2310,"end":2320},"obj":"SP_7"},{"id":"T464","span":{"begin":2321,"end":2326},"obj":"UBERON:0001977"},{"id":"T465","span":{"begin":2338,"end":2341},"obj":"GO:0071735"},{"id":"T466","span":{"begin":2360,"end":2363},"obj":"GO:0071735"},{"id":"T467","span":{"begin":2373,"end":2376},"obj":"GO:0071735"},{"id":"T468","span":{"begin":2413,"end":2423},"obj":"SP_7"},{"id":"T469","span":{"begin":2480,"end":2485},"obj":"UBERON:0002405;GO:0006955"},{"id":"T470","span":{"begin":2486,"end":2496},"obj":"GO:0006955"},{"id":"T471","span":{"begin":2512,"end":2526},"obj":"GO:0065007"},{"id":"T472","span":{"begin":2589,"end":2598},"obj":"NCBITaxon:2"},{"id":"T473","span":{"begin":2644,"end":2649},"obj":"UBERON:0002405;GO:0006955"},{"id":"T474","span":{"begin":2650,"end":2660},"obj":"GO:0006955"}],"attributes":[{"subj":"T186","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T187","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T188","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T189","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T190","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T191","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T192","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T193","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T194","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T195","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T196","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T197","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T198","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T199","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T200","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T201","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T202","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T203","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T204","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T205","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T206","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T207","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T208","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T209","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T210","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T211","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T212","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T213","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T214","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T215","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T216","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T217","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T218","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T219","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T220","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T221","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T222","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T223","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T224","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T225","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T226","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T227","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T228","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T229","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T230","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T231","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T232","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T233","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T234","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T235","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T236","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T237","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T238","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T239","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T240","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T241","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T242","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T243","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T244","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T245","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T246","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T247","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T248","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T249","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T250","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T251","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T252","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T253","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T254","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T400","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T401","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T402","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T403","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T404","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T405","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T406","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T407","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T408","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T409","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T410","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T411","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T412","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T413","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T414","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T415","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T416","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T417","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T418","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T419","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T420","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T421","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T422","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T423","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T424","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T425","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T426","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T427","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T428","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T429","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T430","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T431","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T432","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T98490","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T81900","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T4731","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T98663","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T87532","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T7919","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T90937","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T37745","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T25561","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T59339","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T49058","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T11188","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T71125","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T12356","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T4248","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T79682","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T72845","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T54752","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T81988","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T92925","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T35504","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T59865","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T4129","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T21016","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T96566","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T19391","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T65950","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T84161","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T35511","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T7097","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T463","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T464","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T465","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T466","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T467","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T468","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T469","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T470","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T471","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T472","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T473","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T474","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"2_test","denotations":[{"id":"32320677-24782338-19656936","span":{"begin":729,"end":733},"obj":"24782338"}],"attributes":[{"subj":"32320677-24782338-19656936","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"369","span":{"begin":1487,"end":1495},"obj":"Disease"},{"id":"376","span":{"begin":1578,"end":1582},"obj":"Gene"},{"id":"377","span":{"begin":1594,"end":1602},"obj":"Species"},{"id":"378","span":{"begin":1640,"end":1650},"obj":"Species"},{"id":"379","span":{"begin":1541,"end":1546},"obj":"Species"},{"id":"380","span":{"begin":1720,"end":1735},"obj":"Disease"},{"id":"381","span":{"begin":1776,"end":1784},"obj":"Disease"},{"id":"385","span":{"begin":1846,"end":1850},"obj":"Gene"},{"id":"386","span":{"begin":1890,"end":1898},"obj":"Species"},{"id":"387","span":{"begin":1918,"end":1928},"obj":"Species"},{"id":"392","span":{"begin":2031,"end":2039},"obj":"Species"},{"id":"393","span":{"begin":2088,"end":2091},"obj":"Species"},{"id":"394","span":{"begin":2092,"end":2097},"obj":"Species"},{"id":"395","span":{"begin":2063,"end":2069},"obj":"Disease"},{"id":"398","span":{"begin":2178,"end":2186},"obj":"Species"},{"id":"399","span":{"begin":2206,"end":2216},"obj":"Species"},{"id":"402","span":{"begin":2312,"end":2320},"obj":"Species"},{"id":"403","span":{"begin":2340,"end":2350},"obj":"Species"},{"id":"406","span":{"begin":2444,"end":2452},"obj":"Species"},{"id":"407","span":{"begin":2472,"end":2482},"obj":"Species"},{"id":"428","span":{"begin":104,"end":108},"obj":"Gene"},{"id":"429","span":{"begin":296,"end":300},"obj":"Gene"},{"id":"430","span":{"begin":968,"end":972},"obj":"Gene"},{"id":"431","span":{"begin":1155,"end":1159},"obj":"Gene"},{"id":"432","span":{"begin":172,"end":182},"obj":"Species"},{"id":"433","span":{"begin":213,"end":221},"obj":"Species"},{"id":"434","span":{"begin":414,"end":422},"obj":"Species"},{"id":"435","span":{"begin":428,"end":438},"obj":"Species"},{"id":"436","span":{"begin":504,"end":514},"obj":"Species"},{"id":"437","span":{"begin":742,"end":750},"obj":"Species"},{"id":"438","span":{"begin":756,"end":766},"obj":"Species"},{"id":"439","span":{"begin":864,"end":872},"obj":"Species"},{"id":"440","span":{"begin":1009,"end":1017},"obj":"Species"},{"id":"441","span":{"begin":1028,"end":1036},"obj":"Species"},{"id":"442","span":{"begin":1062,"end":1072},"obj":"Species"},{"id":"443","span":{"begin":1356,"end":1364},"obj":"Species"},{"id":"444","span":{"begin":1396,"end":1404},"obj":"Species"},{"id":"445","span":{"begin":0,"end":25},"obj":"Disease"},{"id":"446","span":{"begin":1042,"end":1051},"obj":"Disease"},{"id":"447","span":{"begin":1243,"end":1246},"obj":"Disease"}],"attributes":[{"id":"A369","pred":"tao:has_database_id","subj":"369","obj":"MESH:C000657245"},{"id":"A376","pred":"tao:has_database_id","subj":"376","obj":"Gene:929"},{"id":"A377","pred":"tao:has_database_id","subj":"377","obj":"Tax:9606"},{"id":"A378","pred":"tao:has_database_id","subj":"378","obj":"Tax:2697049"},{"id":"A379","pred":"tao:has_database_id","subj":"379","obj":"Tax:9606"},{"id":"A381","pred":"tao:has_database_id","subj":"381","obj":"MESH:C000657245"},{"id":"A385","pred":"tao:has_database_id","subj":"385","obj":"Gene:929"},{"id":"A386","pred":"tao:has_database_id","subj":"386","obj":"Tax:9606"},{"id":"A387","pred":"tao:has_database_id","subj":"387","obj":"Tax:2697049"},{"id":"A392","pred":"tao:has_database_id","subj":"392","obj":"Tax:9606"},{"id":"A393","pred":"tao:has_database_id","subj":"393","obj":"Tax:2698737"},{"id":"A394","pred":"tao:has_database_id","subj":"394","obj":"Tax:2697049"},{"id":"A395","pred":"tao:has_database_id","subj":"395","obj":"MESH:D018805"},{"id":"A398","pred":"tao:has_database_id","subj":"398","obj":"Tax:9606"},{"id":"A399","pred":"tao:has_database_id","subj":"399","obj":"Tax:2697049"},{"id":"A402","pred":"tao:has_database_id","subj":"402","obj":"Tax:9606"},{"id":"A403","pred":"tao:has_database_id","subj":"403","obj":"Tax:2697049"},{"id":"A406","pred":"tao:has_database_id","subj":"406","obj":"Tax:9606"},{"id":"A407","pred":"tao:has_database_id","subj":"407","obj":"Tax:2697049"},{"id":"A428","pred":"tao:has_database_id","subj":"428","obj":"Gene:929"},{"id":"A429","pred":"tao:has_database_id","subj":"429","obj":"Gene:929"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"Gene:929"},{"id":"A431","pred":"tao:has_database_id","subj":"431","obj":"Gene:929"},{"id":"A432","pred":"tao:has_database_id","subj":"432","obj":"Tax:2697049"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"Tax:9606"},{"id":"A434","pred":"tao:has_database_id","subj":"434","obj":"Tax:9606"},{"id":"A435","pred":"tao:has_database_id","subj":"435","obj":"Tax:2697049"},{"id":"A436","pred":"tao:has_database_id","subj":"436","obj":"Tax:2697049"},{"id":"A437","pred":"tao:has_database_id","subj":"437","obj":"Tax:9606"},{"id":"A438","pred":"tao:has_database_id","subj":"438","obj":"Tax:2697049"},{"id":"A439","pred":"tao:has_database_id","subj":"439","obj":"Tax:9606"},{"id":"A440","pred":"tao:has_database_id","subj":"440","obj":"Tax:9606"},{"id":"A441","pred":"tao:has_database_id","subj":"441","obj":"Tax:9606"},{"id":"A442","pred":"tao:has_database_id","subj":"442","obj":"Tax:2697049"},{"id":"A443","pred":"tao:has_database_id","subj":"443","obj":"Tax:9606"},{"id":"A444","pred":"tao:has_database_id","subj":"444","obj":"Tax:9606"},{"id":"A445","pred":"tao:has_database_id","subj":"445","obj":"MESH:D018805"},{"id":"A446","pred":"tao:has_database_id","subj":"446","obj":"MESH:D011014"},{"subj":"369","pred":"source","obj":"LitCovid-PubTator"},{"subj":"376","pred":"source","obj":"LitCovid-PubTator"},{"subj":"377","pred":"source","obj":"LitCovid-PubTator"},{"subj":"378","pred":"source","obj":"LitCovid-PubTator"},{"subj":"379","pred":"source","obj":"LitCovid-PubTator"},{"subj":"380","pred":"source","obj":"LitCovid-PubTator"},{"subj":"381","pred":"source","obj":"LitCovid-PubTator"},{"subj":"385","pred":"source","obj":"LitCovid-PubTator"},{"subj":"386","pred":"source","obj":"LitCovid-PubTator"},{"subj":"387","pred":"source","obj":"LitCovid-PubTator"},{"subj":"392","pred":"source","obj":"LitCovid-PubTator"},{"subj":"393","pred":"source","obj":"LitCovid-PubTator"},{"subj":"394","pred":"source","obj":"LitCovid-PubTator"},{"subj":"395","pred":"source","obj":"LitCovid-PubTator"},{"subj":"398","pred":"source","obj":"LitCovid-PubTator"},{"subj":"399","pred":"source","obj":"LitCovid-PubTator"},{"subj":"402","pred":"source","obj":"LitCovid-PubTator"},{"subj":"403","pred":"source","obj":"LitCovid-PubTator"},{"subj":"406","pred":"source","obj":"LitCovid-PubTator"},{"subj":"407","pred":"source","obj":"LitCovid-PubTator"},{"subj":"428","pred":"source","obj":"LitCovid-PubTator"},{"subj":"429","pred":"source","obj":"LitCovid-PubTator"},{"subj":"430","pred":"source","obj":"LitCovid-PubTator"},{"subj":"431","pred":"source","obj":"LitCovid-PubTator"},{"subj":"432","pred":"source","obj":"LitCovid-PubTator"},{"subj":"433","pred":"source","obj":"LitCovid-PubTator"},{"subj":"434","pred":"source","obj":"LitCovid-PubTator"},{"subj":"435","pred":"source","obj":"LitCovid-PubTator"},{"subj":"436","pred":"source","obj":"LitCovid-PubTator"},{"subj":"437","pred":"source","obj":"LitCovid-PubTator"},{"subj":"438","pred":"source","obj":"LitCovid-PubTator"},{"subj":"439","pred":"source","obj":"LitCovid-PubTator"},{"subj":"440","pred":"source","obj":"LitCovid-PubTator"},{"subj":"441","pred":"source","obj":"LitCovid-PubTator"},{"subj":"442","pred":"source","obj":"LitCovid-PubTator"},{"subj":"443","pred":"source","obj":"LitCovid-PubTator"},{"subj":"444","pred":"source","obj":"LitCovid-PubTator"},{"subj":"445","pred":"source","obj":"LitCovid-PubTator"},{"subj":"446","pred":"source","obj":"LitCovid-PubTator"},{"subj":"447","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#93b1ec","default":true},{"id":"LitCovid-PD-UBERON","color":"#cbec93"},{"id":"LitCovid-PD-MONDO","color":"#ec93e5"},{"id":"LitCovid-PD-CLO","color":"#93ecd8"},{"id":"LitCovid-PD-CHEBI","color":"#ecbe93"},{"id":"LitCovid-sentences","color":"#a493ec"},{"id":"LitCovid-PD-HP","color":"#9bec93"},{"id":"LitCovid-PMC-OGER-BB","color":"#ec93b5"},{"id":"2_test","color":"#93cfec"},{"id":"LitCovid-PubTator","color":"#e9ec93"}]}]}}