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PMC:7170415 / 8397-11172 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
144 152-162 Species denotes SARS–CoV-2 Tax:2697049
145 310-317 Species denotes persons Tax:9606
146 1638-1645 Species denotes persons Tax:9606
147 343-351 Disease denotes COVID-19 MESH:C000657245
148 548-557 Disease denotes infection MESH:D007239
149 1689-1699 Disease denotes infections MESH:D007239
152 1926-1933 Species denotes persons Tax:9606
153 1959-1967 Disease denotes COVID-19 MESH:C000657245
159 2123-2131 Species denotes patients Tax:9606
160 2597-2607 Species denotes SARS–CoV-2 Tax:2697049
161 2685-2695 Species denotes SARS–CoV-2 Tax:2697049
162 2706-2716 Species denotes SARS–CoV-2 Tax:2697049
163 2719-2772 Species denotes severe acute respiratory syndrome–related coronavirus Tax:694009

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T41 152-156 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T42 343-351 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 548-557 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T44 1689-1699 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T45 1959-1967 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 2597-2601 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T47 2685-2689 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T48 2706-2710 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T49 2719-2752 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T65 11-18 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Testing
T66 103-108 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T67 161-167 http://purl.obolibrary.org/obo/CLO_0001196 denotes 2 (25)
T68 296-303 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T69 430-431 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T70 432-436 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T71 465-469 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Test
T72 535-539 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T73 580-585 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T74 635-639 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T75 685-690 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T76 748-749 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T77 785-792 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T78 845-849 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T79 987-991 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T80 1071-1076 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T81 1105-1110 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T82 1193-1198 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T83 1220-1221 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T84 1392-1393 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 1394-1398 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T86 1524-1525 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 1536-1540 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T88 1578-1579 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 1652-1658 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T90 1747-1750 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T91 1761-1762 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 1825-1829 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T93 1912-1919 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T94 1969-1970 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T95 1971-1975 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T96 2186-2190 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T97 2209-2210 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 2239-2243 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T99 2349-2356 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T100 2382-2388 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T101 2528-2533 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T4 2501-2513 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T5 2509-2513 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T9 2543-2560 http://purl.obolibrary.org/obo/GO_0044405 denotes detection of host

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T62 0-19 Sentence denotes Diagnostic Testing:
T63 20-42 Sentence denotes Defining Key Use Cases
T64 43-237 Sentence denotes Despite the remarkable speed with which accurate diagnostic tests have been developed and made available for SARS–CoV-2 (25), current tools only partially meet several clinically relevant needs.
T65 238-352 Sentence denotes Figure 1 illustrates different indications for diagnostic testing among persons with proven or suspected COVID-19.
T66 353-464 Sentence denotes For each of these, the most important consideration is the clinical decision a test result will help to inform.
T67 465-932 Sentence denotes Test designs must account for several parameters, such as whether the test detects infection directly (such as the virus itself) or indirectly (such as host antibodies), test turnaround time, the ability to perform many tests at the same time (that is, throughput), the need to have a minimum number of specimens before testing (that is, batching), and the ability to perform the test in low-infrastructure settings (such as on cruise ships or in remote communities).
T68 933-1003 Sentence denotes The potential for use at the point of care depends on test complexity.
T69 1004-1012 Sentence denotes The U.S.
T70 1013-1097 Sentence denotes Food and Drug Administration (FDA) categorizes diagnostic tests by their complexity:
T71 1098-1233 Sentence denotes Waived tests are available for use at the point of care, whereas moderate- and high-complexity tests must be performed in a laboratory.
T72 1234-1310 Sentence denotes The intended use also determines which specimen types are ideal or feasible.
T73 1311-1430 Sentence denotes Finally, it is important to recognize that the acceptable diagnostic accuracy of a test may vary according to use case.
T74 1431-1700 Sentence denotes For example, sensitivity and specificity requirements of an assay used to confirm results of a screening test need not be as stringent as those of a method used for standalone diagnosis, because the pool of persons being tested is already enriched with true infections.
T75 1701-1863 Sentence denotes The Foundation for Innovative New Diagnostics has published a detailed assessment of priority use cases to be considered by test developers and policymakers (26).
T76 1864-1873 Sentence denotes Figure 1.
T77 1875-1968 Sentence denotes Examples of use cases for diagnostic testing among persons with proven or suspected COVID-19.
T78 1969-2181 Sentence denotes A test well suited for one use case (such as epidemiologic surveillance) may be completely inadequate for another (such as rapid screening of symptomatic patients for allocation of personal protective equipment).
T79 2182-2417 Sentence denotes For test results to enable a specific clinical decision, test developers, policymakers, and clinicians need to consider each of these with respect to the intention of testing and the population being tested as specifically as possible.
T80 2418-2705 Sentence denotes For the moment, most use cases placed above the green and gray bar are best met by nucleic acid amplification tests, whereas detection of host-derived antibodies directed against SARS–CoV-2 will be crucial for surveillance, epidemic forecasting, and determination of SARS–CoV-2 immunity.
T81 2706-2775 Sentence denotes SARS–CoV-2 = severe acute respiratory syndrome–related coronavirus-2.