PMC:7170415 / 27332-28332 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7170415","sourcedb":"PMC","sourceid":"7170415","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7170415","text":"Other Considerations\nCritical considerations for diagnostics used for epidemic diseases of public health importance include the quality assurance and regulatory frameworks surrounding testing. Mature regulatory agencies have developed mechanisms to account for emergencies, such as the FDA's EUA stream, but pragmatic solutions must be found to facilitate wide-scale, independent evaluation of emerging tests.\nInitially, the need for elaborate biosafety precautions and inconsistent recommendations for their application across regions severely hampered COVID-19 testing. Although these continue to evolve, current recommendations in Canada and the United States acknowledge that nonpropagative work for molecular testing may be performed in containment level 2 conditions found in routine diagnostic laboratories and provide specific guidance on diagnostic testing of specimens conducted outside a biosafety level 2 laboratory, such as rapid respiratory testing performed at the point of care (67) .","divisions":[{"label":"title","span":{"begin":0,"end":20}},{"label":"p","span":{"begin":21,"end":409}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"374","span":{"begin":943,"end":954},"obj":"Species"},{"id":"375","span":{"begin":554,"end":562},"obj":"Disease"}],"attributes":[{"id":"A374","pred":"tao:has_database_id","subj":"374","obj":"Tax:12814"},{"id":"A375","pred":"tao:has_database_id","subj":"375","obj":"MESH:C000657245"},{"subj":"374","pred":"source","obj":"LitCovid-PubTator"},{"subj":"375","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T25","span":{"begin":361,"end":366},"obj":"Body_part"}],"attributes":[{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0002542"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T107","span":{"begin":554,"end":562},"obj":"Disease"}],"attributes":[{"id":"A107","pred":"mondo_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T240","span":{"begin":184,"end":191},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T241","span":{"begin":403,"end":408},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T242","span":{"begin":563,"end":570},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T243","span":{"begin":714,"end":721},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T244","span":{"begin":858,"end":865},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T245","span":{"begin":897,"end":898},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T246","span":{"begin":955,"end":962},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"}],"attributes":[{"subj":"T240","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T241","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T242","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T243","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T244","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T245","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T246","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T43","span":{"begin":509,"end":520},"obj":"Chemical"}],"attributes":[{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T187","span":{"begin":0,"end":20},"obj":"Sentence"},{"id":"T188","span":{"begin":21,"end":192},"obj":"Sentence"},{"id":"T189","span":{"begin":193,"end":409},"obj":"Sentence"},{"id":"T190","span":{"begin":410,"end":571},"obj":"Sentence"},{"id":"T191","span":{"begin":572,"end":1000},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T187","pred":"source","obj":"LitCovid-sentences"},{"subj":"T188","pred":"source","obj":"LitCovid-sentences"},{"subj":"T189","pred":"source","obj":"LitCovid-sentences"},{"subj":"T190","pred":"source","obj":"LitCovid-sentences"},{"subj":"T191","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#e5ec93","default":true},{"id":"LitCovid-PD-UBERON","color":"#d993ec"},{"id":"LitCovid-PD-MONDO","color":"#93ecbf"},{"id":"LitCovid-PD-CLO","color":"#eca593"},{"id":"LitCovid-PD-CHEBI","color":"#939bec"},{"id":"LitCovid-sentences","color":"#b5ec93"}]}]}}