PMC:7170415 / 21818-22788
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 329 | 139-157 | Gene | denotes | C-reactive protein | Gene:1401 |
| 330 | 440-464 | Gene | denotes | alanine aminotransferase | Gene:2875 |
| 331 | 48-56 | Species | denotes | patients | Tax:9606 |
| 332 | 679-689 | Species | denotes | SARS–CoV-2 | Tax:2697049 |
| 333 | 761-769 | Species | denotes | patients | Tax:9606 |
| 334 | 470-480 | Chemical | denotes | creatinine | MESH:D003404 |
| 335 | 536-545 | Chemical | denotes | bilirubin | MESH:D001663 |
| 336 | 550-560 | Chemical | denotes | creatinine | MESH:D003404 |
| 337 | 62-70 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 338 | 264-275 | Disease | denotes | lymphopenia | MESH:D008231 |
| 339 | 496-506 | Disease | denotes | leukopenia | MESH:D007970 |
| 340 | 508-520 | Disease | denotes | leukocytosis | MESH:D007964 |
| 341 | 714-735 | Disease | denotes | end-organ dysfunction | MESH:C564816 |
| 342 | 775-781 | Disease | denotes | sepsis | MESH:D018805 |
| 343 | 912-920 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T38 | 150-157 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T39 | 370-381 | Body_part | denotes | erythrocyte | http://purl.org/sig/ont/fma/fma62845 |
| T40 | 440-447 | Body_part | denotes | alanine | http://purl.org/sig/ont/fma/fma82749 |
| T41 | 718-723 | Body_part | denotes | organ | http://purl.org/sig/ont/fma/fma67498 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T21 | 718-723 | Body_part | denotes | organ | http://purl.obolibrary.org/obo/UBERON_0000062 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T97 | 62-70 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T98 | 264-275 | Disease | denotes | lymphopenia | http://purl.obolibrary.org/obo/MONDO_0003783 |
| T99 | 496-506 | Disease | denotes | leukopenia | http://purl.obolibrary.org/obo/MONDO_0003785 |
| T100 | 679-683 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T101 | 912-920 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T204 | 370-381 | http://purl.obolibrary.org/obo/CL_0000232 | denotes | erythrocyte |
| T205 | 718-723 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organ |
| T206 | 897-898 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T24 | 150-157 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T25 | 201-208 | Chemical | denotes | lactate | http://purl.obolibrary.org/obo/CHEBI_24996 |
| T26 | 412-421 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
| T29 | 440-447 | Chemical | denotes | alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
| T30 | 470-480 | Chemical | denotes | creatinine | http://purl.obolibrary.org/obo/CHEBI_16737 |
| T31 | 536-545 | Chemical | denotes | bilirubin | http://purl.obolibrary.org/obo/CHEBI_16990 |
| T32 | 550-560 | Chemical | denotes | creatinine | http://purl.obolibrary.org/obo/CHEBI_16737 |
| T33 | 791-800 | Chemical | denotes | biomarker | http://purl.obolibrary.org/obo/CHEBI_59163 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T155 | 0-310 | Sentence | denotes | The most common laboratory features reported in patients with COVID-19 include decreased albumin (75.8% [95% CI, 30.5% to 100%]), elevated C-reactive protein (58.3% [CI, 21.8% to 94.7%]), and elevated lactate dehydrogenase levels (57.0% [CI, 38.0% to 76.0%]), and lymphopenia (43.1% [CI, 18.9% to 67.3%]) (56). |
| T156 | 311-576 | Sentence | denotes | Other biomarkers that have been reported include increased erythrocyte sedimentation rates; elevated aspartate aminotransferase, alanine aminotransferase, and creatinine kinase levels; leukopenia; leukocytosis; and increased bilirubin and creatinine levels (57–59). |
| T157 | 577-787 | Sentence | denotes | Such findings are not surprising, because these biomarkers represent an inflammatory host response to SARS–CoV-2 or are early markers of end-organ dysfunction, similar to that seen in patients with sepsis (60). |
| T158 | 788-970 | Sentence | denotes | No biomarker or combination of biomarkers currently exists that is sensitive or specific enough to establish a diagnosis of COVID-19, or to pragmatically predict its clinical course. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T5 | 264-275 | Phenotype | denotes | lymphopenia | http://purl.obolibrary.org/obo/HP_0001888 |
| T6 | 360-401 | Phenotype | denotes | increased erythrocyte sedimentation rates | http://purl.obolibrary.org/obo/HP_0003565 |
| T7 | 496-506 | Phenotype | denotes | leukopenia | http://purl.obolibrary.org/obo/HP_0001882 |
| T8 | 508-520 | Phenotype | denotes | leukocytosis | http://purl.obolibrary.org/obo/HP_0001974 |
| T9 | 526-545 | Phenotype | denotes | increased bilirubin | http://purl.obolibrary.org/obo/HP_0003573 |
| T10 | 775-781 | Phenotype | denotes | sepsis | http://purl.obolibrary.org/obo/HP_0100806 |