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PMC:7170368 / 170-1062 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
18 538-542 Gene denotes IL-6 Gene:3569
19 615-618 Gene denotes CD8 Gene:925
20 116-124 Species denotes patients Tax:9606
21 327-335 Species denotes patients Tax:9606
22 427-435 Species denotes patients Tax:9606
23 865-873 Species denotes patients Tax:9606
24 75-96 Disease denotes coronavirus infection MESH:D018352
25 106-114 Disease denotes COVID-19 MESH:C000657245
26 318-326 Disease denotes COVID-19 MESH:C000657245
27 341-353 Disease denotes hypertension MESH:D006973
28 856-864 Disease denotes COVID-19 MESH:C000657245
29 879-891 Disease denotes hypertension MESH:D006973

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 557-562 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T2 621-625 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T3 647-652 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T2 23-47 Body_part denotes renin-angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229
T3 49-52 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T4 138-141 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T5 394-397 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T6 557-562 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T7 647-652 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T3 87-96 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T4 106-114 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 318-326 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 341-353 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T7 454-457 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T8 585-588 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T9 856-864 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 879-891 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 54-57 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 470-471 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 506-507 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 521-522 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 557-562 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T6 557-562 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T7 607-610 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T8 607-610 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T9 615-618 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T10 619-625 http://purl.obolibrary.org/obo/CL_0000084 denotes T cell
T11 647-652 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T12 647-652 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T3 29-40 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T4 49-52 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T5 138-141 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T6 142-152 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T7 162-202 Chemical denotes angiotensin-converting enzyme inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T8 162-173 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T9 185-202 Chemical denotes enzyme inhibitors http://purl.obolibrary.org/obo/CHEBI_23924
T10 192-202 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T11 204-209 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457
T12 215-229 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T15 215-226 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T16 227-229 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T17 394-397 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T18 398-408 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T19 538-540 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T21 705-727 Chemical denotes antihypertensive drugs http://purl.obolibrary.org/obo/CHEBI_35674
T22 722-727 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T23 773-778 Chemical denotes ACEIs http://purl.obolibrary.org/obo/CHEBI_35457

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T7 0-317 Sentence denotes The dysfunction of the renin-angiotensin system (RAS) has been observed in coronavirus infection disease (COVID-19) patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type 1 receptor blockers (ARBs), are associated with clinical outcomes remains unknown.
T8 318-409 Sentence denotes COVID-19 patients with hypertension were enrolled to evaluate the effect of RAS inhibitors.
T9 410-563 Sentence denotes We observed that patients receiving ACEI or ARB therapy had a lower rate of severe diseases and a trend toward a lower level of IL-6 in peripheral blood.
T10 564-728 Sentence denotes In addition, ACEI or ARB therapy increased CD3 and CD8 T cell counts in peripheral blood and decreased the peak viral load compared to other antihypertensive drugs.
T11 729-892 Sentence denotes This evidence supports the benefit of using ACEIs or ARBs to potentially contribute to the improvement of clinical outcomes of COVID-19 patients with hypertension.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 341-353 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T3 879-891 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822