PMC:7166305 / 513-1444 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":24,"end":47},"obj":"Body_part"},{"id":"T5","span":{"begin":49,"end":52},"obj":"Body_part"},{"id":"T6","span":{"begin":148,"end":151},"obj":"Body_part"},{"id":"T7","span":{"begin":450,"end":453},"obj":"Body_part"},{"id":"T8","span":{"begin":599,"end":602},"obj":"Body_part"},{"id":"T9","span":{"begin":681,"end":688},"obj":"Body_part"},{"id":"T10","span":{"begin":760,"end":763},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma63170"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma63170"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma63170"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma63170"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma63170"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma63170"}],"text":"In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection: 3.5 (3.0–4.4); on admission: 2.8 (2.3–3.1), p \u003c 0.01; progression: 2.5 (2.3–3.0); discharge: 3.6 (2.7–4.1); median (IQR), in mmol/L). In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission). The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels. Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio: 4.48, 95% IC: 1.55–12.92, p = 0.006) and in-hospital death (odds ratio: 21.72, 95% IC: 1.40–337.54, p = 0.028)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":133,"end":142},"obj":"Disease"},{"id":"T8","span":{"begin":278,"end":287},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection: 3.5 (3.0–4.4); on admission: 2.8 (2.3–3.1), p \u003c 0.01; progression: 2.5 (2.3–3.0); discharge: 3.6 (2.7–4.1); median (IQR), in mmol/L). In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission). The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels. Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio: 4.48, 95% IC: 1.55–12.92, p = 0.006) and in-hospital death (odds ratio: 21.72, 95% IC: 1.40–337.54, p = 0.028)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T6","span":{"begin":24,"end":47},"obj":"Chemical"},{"id":"T7","span":{"begin":36,"end":47},"obj":"Chemical"},{"id":"T8","span":{"begin":49,"end":52},"obj":"Chemical"},{"id":"T9","span":{"begin":148,"end":151},"obj":"Chemical"},{"id":"T10","span":{"begin":450,"end":453},"obj":"Chemical"},{"id":"T11","span":{"begin":599,"end":602},"obj":"Chemical"},{"id":"T12","span":{"begin":681,"end":688},"obj":"Chemical"},{"id":"T13","span":{"begin":760,"end":763},"obj":"Chemical"}],"attributes":[{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_6495"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_39026"}],"text":"In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection: 3.5 (3.0–4.4); on admission: 2.8 (2.3–3.1), p \u003c 0.01; progression: 2.5 (2.3–3.0); discharge: 3.6 (2.7–4.1); median (IQR), in mmol/L). In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission). The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels. Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio: 4.48, 95% IC: 1.55–12.92, p = 0.006) and in-hospital death (odds ratio: 21.72, 95% IC: 1.40–337.54, p = 0.028)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T10","span":{"begin":0,"end":288},"obj":"Sentence"},{"id":"T11","span":{"begin":289,"end":317},"obj":"Sentence"},{"id":"T12","span":{"begin":318,"end":355},"obj":"Sentence"},{"id":"T13","span":{"begin":356,"end":381},"obj":"Sentence"},{"id":"T14","span":{"begin":382,"end":422},"obj":"Sentence"},{"id":"T15","span":{"begin":423,"end":577},"obj":"Sentence"},{"id":"T16","span":{"begin":578,"end":696},"obj":"Sentence"},{"id":"T17","span":{"begin":697,"end":819},"obj":"Sentence"},{"id":"T18","span":{"begin":820,"end":833},"obj":"Sentence"},{"id":"T19","span":{"begin":834,"end":891},"obj":"Sentence"},{"id":"T20","span":{"begin":892,"end":906},"obj":"Sentence"},{"id":"T21","span":{"begin":907,"end":931},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection: 3.5 (3.0–4.4); on admission: 2.8 (2.3–3.1), p \u003c 0.01; progression: 2.5 (2.3–3.0); discharge: 3.6 (2.7–4.1); median (IQR), in mmol/L). In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission). The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels. Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio: 4.48, 95% IC: 1.55–12.92, p = 0.006) and in-hospital death (odds ratio: 21.72, 95% IC: 1.40–337.54, p = 0.028)."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T10","span":{"begin":514,"end":519},"obj":"GO:0016265"},{"id":"T11","span":{"begin":670,"end":688},"obj":"PR:000005897"},{"id":"T12","span":{"begin":873,"end":878},"obj":"GO:0016265"},{"id":"T30280","span":{"begin":514,"end":519},"obj":"GO:0016265"},{"id":"T58122","span":{"begin":670,"end":688},"obj":"PR:000005897"},{"id":"T71297","span":{"begin":873,"end":878},"obj":"GO:0016265"}],"text":"In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection: 3.5 (3.0–4.4); on admission: 2.8 (2.3–3.1), p \u003c 0.01; progression: 2.5 (2.3–3.0); discharge: 3.6 (2.7–4.1); median (IQR), in mmol/L). In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission). The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels. Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio: 4.48, 95% IC: 1.55–12.92, p = 0.006) and in-hospital death (odds ratio: 21.72, 95% IC: 1.40–337.54, p = 0.028)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"23","span":{"begin":670,"end":688},"obj":"Gene"},{"id":"24","span":{"begin":254,"end":262},"obj":"Species"},{"id":"25","span":{"begin":440,"end":448},"obj":"Species"},{"id":"26","span":{"begin":133,"end":142},"obj":"Disease"},{"id":"27","span":{"begin":278,"end":287},"obj":"Disease"},{"id":"28","span":{"begin":514,"end":519},"obj":"Disease"},{"id":"29","span":{"begin":873,"end":878},"obj":"Disease"}],"attributes":[{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"Gene:1401"},{"id":"A24","pred":"tao:has_database_id","subj":"24","obj":"Tax:9606"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"Tax:9606"},{"id":"A26","pred":"tao:has_database_id","subj":"26","obj":"MESH:D007239"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"MESH:D007239"},{"id":"A28","pred":"tao:has_database_id","subj":"28","obj":"MESH:D003643"},{"id":"A29","pred":"tao:has_database_id","subj":"29","obj":"MESH:D003643"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection: 3.5 (3.0–4.4); on admission: 2.8 (2.3–3.1), p \u003c 0.01; progression: 2.5 (2.3–3.0); discharge: 3.6 (2.7–4.1); median (IQR), in mmol/L). In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission). The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels. Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio: 4.48, 95% IC: 1.55–12.92, p = 0.006) and in-hospital death (odds ratio: 21.72, 95% IC: 1.40–337.54, p = 0.028)."}