PMC:7161517 / 9777-11799
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T55 | 521-537 | Body_part | denotes | zona glomerulosa | http://purl.org/sig/ont/fma/fma69225 |
| T56 | 545-560 | Body_part | denotes | adrenal medulla | http://purl.org/sig/ont/fma/fma15633 |
| T57 | 779-798 | Body_part | denotes | posterior pituitary | http://purl.org/sig/ont/fma/fma74636 |
| T58 | 818-838 | Body_part | denotes | antidiuretic hormone | http://purl.org/sig/ont/fma/fma74646 |
| T59 | 893-900 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
| T60 | 1263-1267 | Body_part | denotes | axis | http://purl.org/sig/ont/fma/fma12520 |
| T61 | 1717-1724 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T62 | 1775-1782 | Body_part | denotes | cytosol | http://purl.org/sig/ont/fma/fma66836 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T35 | 33-36 | Body_part | denotes | RAS | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T36 | 238-262 | Body_part | denotes | Renin-Angiotensin System | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T37 | 545-560 | Body_part | denotes | adrenal medulla | http://purl.obolibrary.org/obo/UBERON_0001236 |
| T38 | 1324-1348 | Body_part | denotes | renin-angiotensin system | http://purl.obolibrary.org/obo/UBERON_0018229 |
| T39 | 1350-1353 | Body_part | denotes | RAS | http://purl.obolibrary.org/obo/UBERON_0018229 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T51 | 40-62 | Disease | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T52 | 164-187 | Disease | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/MONDO_0004995 |
| T53 | 280-288 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T54 | 789-798 | Disease | denotes | pituitary | http://purl.obolibrary.org/obo/MONDO_0021156 |
| T55 | 1462-1465 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
| T56 | 1628-1661 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T57 | 1675-1683 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T58 | 1691-1699 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T59 | 1799-1808 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T106 | 114-117 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T107 | 779-788 | http://purl.obolibrary.org/obo/UBERON_0001353 | denotes | posterior |
| T108 | 1276-1277 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T109 | 1570-1573 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T113 | 33-36 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
| T114 | 83-97 | Chemical | denotes | ACE inhibitors | http://purl.obolibrary.org/obo/CHEBI_35457 |
| T115 | 87-97 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T116 | 244-255 | Chemical | denotes | Angiotensin | http://purl.obolibrary.org/obo/CHEBI_2719 |
| T117 | 299-310 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T118 | 341-343 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T119 | 348-359 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T120 | 413-427 | Chemical | denotes | ACE inhibitors | http://purl.obolibrary.org/obo/CHEBI_35457 |
| T121 | 417-427 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T122 | 465-467 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T123 | 576-587 | Chemical | denotes | aldosterone | http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834 |
| T125 | 613-630 | Chemical | denotes | mineralocorticoid | http://purl.obolibrary.org/obo/CHEBI_25354 |
| T126 | 652-657 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T127 | 687-691 | Chemical | denotes | salt | http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710 |
| T129 | 722-739 | Chemical | denotes | mineralocorticoid | http://purl.obolibrary.org/obo/CHEBI_25354 |
| T130 | 749-760 | Chemical | denotes | antagonists | http://purl.obolibrary.org/obo/CHEBI_48706 |
| T131 | 804-806 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T132 | 831-838 | Chemical | denotes | hormone | http://purl.obolibrary.org/obo/CHEBI_24621 |
| T133 | 860-865 | Chemical | denotes | water | http://purl.obolibrary.org/obo/CHEBI_15377 |
| T134 | 1029-1040 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T135 | 1083-1085 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T136 | 1107-1109 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T137 | 1135-1146 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T138 | 1330-1341 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T139 | 1350-1353 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
| T140 | 1387-1389 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T141 | 1539-1541 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
| T142 | 1717-1724 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T143 | 1849-1851 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T37 | 68-78 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T38 | 576-597 | http://purl.obolibrary.org/obo/GO_0035932 | denotes | aldosterone secretion |
| T39 | 588-597 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T40 | 692-701 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | retention |
| T41 | 831-848 | http://purl.obolibrary.org/obo/GO_0046879 | denotes | hormone secretion |
| T42 | 839-848 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
| T43 | 866-875 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | retention |
| T44 | 986-995 | http://purl.obolibrary.org/obo/GO_0097194 | denotes | apoptosis |
| T45 | 986-995 | http://purl.obolibrary.org/obo/GO_0006915 | denotes | apoptosis |
| T46 | 1449-1460 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
| T47 | 1755-1774 | http://purl.obolibrary.org/obo/GO_0044409 | denotes | entry into the host |
| T48 | 1813-1830 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
| T49 | 1813-1830 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T68 | 0-212 | Sentence | denotes | Because of the importance of the RAS in cardiovascular disease, its regulation via ACE inhibitors, ARBs, and MRAs has played an essential role in the management of cardiovascular diseases (Central Illustration ). |
| T69 | 213-288 | Sentence | denotes | Central Illustration The Renin-Angiotensin System Interaction With COVID-19 |
| T70 | 289-428 | Sentence | denotes | Normally, angiotensin I (Ang I) is converted to Ang II via angiotensin-converting enzyme (ACE), which could be inhibited by ACE inhibitors. |
| T71 | 429-510 | Sentence | denotes | The pro-inflammatory effects of Ang II are mediated through AT1R in several ways: |
| T72 | 511-996 | Sentence | denotes | 1) in the zona glomerulosa of the adrenal medulla, it stimulates aldosterone secretion and binding to mineralocorticoid receptors to promote water reabsorption and to increase salt retention; it is inhibited by mineralocorticoid receptor antagonists (MRAs); 2) in the posterior pituitary, Ang II stimulates antidiuretic hormone secretion to promote water retention; and 3) in other tissues, it stimulates pathways responsible for hypertrophy, fibrosis, oxidative stress, and apoptosis. |
| T73 | 997-1102 | Sentence | denotes | These effects are attenuated by angiotensin receptor blockers (ARBs), which block Ang II binding to AT1R. |
| T74 | 1103-1242 | Sentence | denotes | Ang II can also be converted to angiotensin 1-7 (Ang 1-7) via ACE2, which stimulates the Mas receptor promoting anti-inflammatory benefits. |
| T75 | 1243-1355 | Sentence | denotes | The ACE2/Ang1-7/Mas axis acts as a counter regulatory pathway to the traditional renin-angiotensin system (RAS). |
| T76 | 1356-1382 | Sentence | denotes | AT1R and ACE2 are coupled. |
| T77 | 1383-1461 | Sentence | denotes | Ang II binding to AT1R allows dissociation of ACE2 and subsequent degradation. |
| T78 | 1462-1564 | Sentence | denotes | ARB prevents dissociation of ACE2 and renders it availability for unused Ang II conversion to Ang 1-7. |
| T79 | 1565-1700 | Sentence | denotes | ACE2 has been identified as the targeted receptor for both the severe acute respiratory syndrome coronavirus (SARS-CoV) 2 and SARS-CoV. |
| T80 | 1701-1831 | Sentence | denotes | ACE2 mediates S protein binding that stimulates viral entry into the host cytosol that results in infection and viral replication. |
| T81 | 1832-2022 | Sentence | denotes | Diversion of Ang II towards ACE2 could competitively inhibit viral binding and also counter regulate the adverse effects caused by AT1R and improve outcomes by Mas R−based favorable effects. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T10 | 40-62 | Phenotype | denotes | cardiovascular disease | http://purl.obolibrary.org/obo/HP_0001626 |
| T11 | 164-187 | Phenotype | denotes | cardiovascular diseases | http://purl.obolibrary.org/obo/HP_0001626 |
| T12 | 860-875 | Phenotype | denotes | water retention | http://purl.obolibrary.org/obo/HP_0000969 |
| T13 | 964-980 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T348 | 40-54 | UBERON:0004535 | denotes | cardiovascular |
| T349 | 68-78 | GO:0065007 | denotes | regulation |
| T350 | 87-97 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T351 | 164-178 | UBERON:0004535 | denotes | cardiovascular |
| T352 | 238-243 | PR:000013883 | denotes | Renin |
| T353 | 280-297 | SP_7 | denotes | COVID-19 Normally |
| T354 | 299-312 | PR:000036008 | denotes | angiotensin I |
| T355 | 314-319 | PR:000036008 | denotes | Ang I |
| T356 | 337-343 | PR:000036009 | denotes | Ang II |
| T357 | 417-427 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T358 | 461-467 | PR:000036009 | denotes | Ang II |
| T359 | 489-493 | PR:000001251 | denotes | AT1R |
| T360 | 521-537 | UBERON:0002053 | denotes | zona glomerulosa |
| T361 | 545-560 | UBERON:0001236 | denotes | adrenal medulla |
| T362 | 576-587 | CHEBI:27584;CHEBI:27584 | denotes | aldosterone |
| T363 | 613-630 | CHEBI:25354;CHEBI:25354 | denotes | mineralocorticoid |
| T364 | 652-657 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T365 | 687-691 | CHEBI:24866;CHEBI:24866 | denotes | salt |
| T366 | 722-739 | CHEBI:25354;CHEBI:25354 | denotes | mineralocorticoid |
| T367 | 740-760 | CHEBI:48561;CHEBI:48561 | denotes | receptor antagonists |
| T368 | 789-798 | UBERON:0002198 | denotes | pituitary |
| T369 | 800-806 | PR:000036009 | denotes | Ang II |
| T370 | 860-865 | CHEBI:15377;CHEBI:15377 | denotes | water |
| T371 | 893-900 | UBERON:0000479 | denotes | tissues |
| T372 | 964-973 | MOP:0000568 | denotes | oxidative |
| T373 | 986-995 | GO:0006915 | denotes | apoptosis |
| T374 | 1079-1082 | CHEBI:37886;CHEBI:37886;PR:000036009 | denotes | Ang |
| T375 | 1083-1085 | PR:000036009 | denotes | II |
| T376 | 1097-1101 | PR:000001251 | denotes | AT1R |
| T377 | 1103-1109 | PR:000036009 | denotes | Ang II |
| T378 | 1135-1148 | PR:000036013 | denotes | angiotensin 1 |
| T379 | 1152-1157 | PR:000036013 | denotes | Ang 1 |
| T380 | 1165-1169 | PR:000003622;G_3;PG_10 | denotes | ACE2 |
| T381 | 1192-1195 | PR:000001563 | denotes | Mas |
| T382 | 1247-1251 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T383 | 1252-1256 | PR:000036013 | denotes | Ang1 |
| T384 | 1324-1329 | PR:000013883 | denotes | renin |
| T385 | 1356-1360 | PR:000001251 | denotes | AT1R |
| T386 | 1365-1369 | PR:000003622;G_3;PG_10 | denotes | ACE2 |
| T387 | 1383-1389 | PR:000036009 | denotes | Ang II |
| T388 | 1401-1405 | PR:000001251 | denotes | AT1R |
| T389 | 1429-1433 | PR:000003622;G_3;PG_10 | denotes | ACE2 |
| T390 | 1491-1495 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T391 | 1535-1541 | PR:000036009 | denotes | Ang II |
| T392 | 1556-1561 | PR:000036013 | denotes | Ang 1 |
| T393 | 1565-1569 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T394 | 1628-1640 | SP_10 | denotes | severe acute |
| T395 | 1641-1652 | SP_10;UBERON:0001004 | denotes | respiratory |
| T396 | 1653-1673 | SP_10 | denotes | syndrome coronavirus |
| T397 | 1675-1683 | SP_10 | denotes | SARS-CoV |
| T398 | 1691-1699 | SP_10 | denotes | SARS-CoV |
| T399 | 1701-1705 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
| T400 | 1715-1724 | PG_1 | denotes | S protein |
| T401 | 1749-1754 | NCBITaxon:10239;GO:0035376 | denotes | viral |
| T402 | 1755-1760 | GO:0035376 | denotes | entry |
| T403 | 1770-1782 | GO:0044164 | denotes | host cytosol |
| T404 | 1813-1818 | NCBITaxon:10239;GO:0006260 | denotes | viral |
| T405 | 1819-1830 | GO:0006260 | denotes | replication |
| T406 | 1845-1851 | PR:000036009 | denotes | Ang II |
| T407 | 1860-1864 | PR:000003622;G_3;PG_10 | denotes | ACE2 |
| T408 | 1893-1898 | NCBITaxon:10239 | denotes | viral |
| T409 | 1963-1967 | PR:000001251 | denotes | AT1R |
| T410 | 1992-1997 | PR:000001607 | denotes | Mas R |
| T48220 | 1627-1638 | CL:0000581 | denotes | severe acu |
| T423 | 23-40 | CHEBI:25354;CHEBI:25354 | denotes | ce of the RAS in |
| T424 | 41-61 | CHEBI:48561;CHEBI:48561 | denotes | ardiovascular diseas |
| T425 | 90-98 | UBERON:0002198 | denotes | ibitors, |
| T426 | 100-106 | PR:000036009 | denotes | RBs, a |
| T427 | 159-164 | CHEBI:15377;CHEBI:15377 | denotes | t of |
| T428 | 192-199 | UBERON:0000479 | denotes | tral Il |
| T429 | 262-270 | MOP:0000568 | denotes | Interac |
| T430 | 283-292 | GO:0006915 | denotes | ID-19 Nor |
| T431 | 375-378 | CHEBI:37886;CHEBI:37886;PR:000036009 | denotes | me |
| T432 | 379-381 | PR:000036009 | denotes | AC |
| T433 | 393-397 | PR:000001251 | denotes | uld |
| T434 | 399-405 | PR:000036009 | denotes | inhib |
| T435 | 431-444 | PR:000036013 | denotes | e pro-inflamm |
| T436 | 448-453 | PR:000036013 | denotes | y eff |
| T437 | 461-465 | PR:000003622;G_3;PG_10 | denotes | Ang |
| T438 | 487-490 | PR:000001563 | denotes | h A |
| T439 | 542-546 | G_3;PG_10;PR:000003622 | denotes | he a |
| T440 | 547-551 | PR:000036013 | denotes | rena |
| T441 | 619-624 | PR:000013883 | denotes | locor |
| T442 | 651-655 | PR:000001251 | denotes | wat |
| T443 | 660-664 | PR:000003622;G_3;PG_10 | denotes | abso |
| T444 | 678-684 | PR:000036009 | denotes | increa |
| T445 | 696-700 | PR:000001251 | denotes | ntio |
| T446 | 724-728 | PR:000003622;G_3;PG_10 | denotes | nera |
| T447 | 786-791 | G_3;PG_10;PR:000003622 | denotes | or pi |
| T448 | 831-837 | PR:000036009 | denotes | hormon |
| T449 | 852-857 | PR:000036013 | denotes | promo |
| T450 | 861-865 | G_3;PG_10;PR:000003622 | denotes | ater |
| T451 | 925-937 | SP_10 | denotes | responsible |
| T452 | 938-948 | SP_10;UBERON:0001004 | denotes | or hypertr |
| T453 | 949-970 | SP_10 | denotes | phy, fibrosis, oxidat |
| T454 | 972-980 | SP_10 | denotes | e stress |
| T455 | 988-996 | SP_10 | denotes | optosis. |
| T456 | 998-1002 | G_3;PG_10;PR:000003622 | denotes | hese |
| T457 | 1012-1022 | PG_1 | denotes | re attenua |
| T458 | 1046-1051 | NCBITaxon:10239;GO:0035376 | denotes | tor b |
| T459 | 1052-1057 | GO:0035376 | denotes | ocker |
| T460 | 1067-1079 | GO:0044164 | denotes | which block |
| T461 | 1110-1115 | NCBITaxon:10239;GO:0006260 | denotes | can a |
| T462 | 1116-1127 | GO:0006260 | denotes | so be conve |
| T463 | 1142-1148 | PR:000036009 | denotes | nsin 1 |
| T464 | 1157-1161 | PR:000003622;G_3;PG_10 | denotes | -7) |
| T465 | 1191-1196 | NCBITaxon:10239 | denotes | Mas |
| T466 | 1261-1266 | PR:000001251 | denotes | s axi |
| T467 | 1291-1296 | PR:000001607 | denotes | atory |
| T89708 | 1372-1376 | CHEBI:23888;CHEBI:23888 | denotes | e co |
| T16250 | 1392-1402 | GO:0065007 | denotes | nding to A |
| T24993 | 1410-1414 | G_3;PG_10;PR:000003622 | denotes | ws d |
| T40191 | 1415-1419 | PR:000036013 | denotes | ssoc |
| T14894 | 1431-1436 | NCBITaxon:10088 | denotes | E2 an |
| T95497 | 1437-1447 | UBERON:0001179;CL:0000581 | denotes | subsequen |
| T5844 | 1448-1459 | CL:0000581 | denotes | degradatio |
| T3127 | 1482-1493 | CHEBI:27584;CHEBI:27584 | denotes | ation of AC |
| T32730 | 1592-1596 | G_3;PG_10;PR:000003622 | denotes | the |
| T99955 | 1610-1615 | NCBITaxon:10088 | denotes | ptor |
| T27470 | 1616-1626 | UBERON:0001179;CL:0000581 | denotes | or both th |
| T26688 | 1653-1665 | CHEBI:17154;CHEBI:17154 | denotes | syndrome cor |
| T64863 | 1686-1695 | CHEBI:18367;CHEBI:18367 | denotes | and SARS |
| T51748 | 1703-1712 | CHEBI:35222;CHEBI:35222 | denotes | E2 mediat |
| T79147 | 1714-1725 | CHEBI:27584;CHEBI:27584 | denotes | S protein |
| T23025 | 1762-1766 | G_3;PG_10;PR:000003622 | denotes | nto |
| T84481 | 1823-1835 | CHEBI:17154;CHEBI:17154 | denotes | ication. Div |
| T4704 | 1941-1951 | CHEBI:31547;CHEBI:31547 | denotes | rse effect |
| T67581 | 1959-1964 | SP_6;NCBITaxon:9606 | denotes | by A |
| T67016 | 1965-1973 | CL:0000576 | denotes | 1R and i |
| T80087 | 1982-1993 | CL:0000235 | denotes | tcomes by M |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 431 | 280-288 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 470 | 299-312 | Gene | denotes | angiotensin I | Gene:183 |
| 471 | 314-319 | Gene | denotes | Ang I | Gene:183 |
| 472 | 337-343 | Gene | denotes | Ang II | Gene:183 |
| 473 | 348-377 | Gene | denotes | angiotensin-converting enzyme | Gene:1636 |
| 474 | 379-382 | Gene | denotes | ACE | Gene:1636 |
| 475 | 413-416 | Gene | denotes | ACE | Gene:1636 |
| 476 | 461-467 | Gene | denotes | Ang II | Gene:183 |
| 477 | 489-493 | Gene | denotes | AT1R | Gene:185 |
| 478 | 722-748 | Gene | denotes | mineralocorticoid receptor | Gene:4306 |
| 479 | 800-806 | Gene | denotes | Ang II | Gene:183 |
| 480 | 1079-1085 | Gene | denotes | Ang II | Gene:183 |
| 481 | 1097-1101 | Gene | denotes | AT1R | Gene:185 |
| 482 | 1103-1109 | Gene | denotes | Ang II | Gene:183 |
| 483 | 1152-1159 | Gene | denotes | Ang 1-7 | Gene:284 |
| 484 | 1165-1169 | Gene | denotes | ACE2 | Gene:59272 |
| 485 | 1247-1251 | Gene | denotes | ACE2 | Gene:59272 |
| 486 | 1252-1258 | Gene | denotes | Ang1-7 | Gene:284 |
| 487 | 1356-1360 | Gene | denotes | AT1R | Gene:185 |
| 488 | 1365-1369 | Gene | denotes | ACE2 | Gene:59272 |
| 489 | 1383-1389 | Gene | denotes | Ang II | Gene:183 |
| 490 | 1401-1405 | Gene | denotes | AT1R | Gene:185 |
| 491 | 1429-1433 | Gene | denotes | ACE2 | Gene:59272 |
| 492 | 1491-1495 | Gene | denotes | ACE2 | Gene:59272 |
| 493 | 1556-1563 | Gene | denotes | Ang 1-7 | Gene:284 |
| 494 | 1565-1569 | Gene | denotes | ACE2 | Gene:59272 |
| 495 | 1701-1705 | Gene | denotes | ACE2 | Gene:59272 |
| 496 | 1860-1864 | Gene | denotes | ACE2 | Gene:59272 |
| 497 | 1963-1967 | Gene | denotes | AT1R | Gene:185 |
| 498 | 1535-1541 | Gene | denotes | Ang II | Gene:183 |
| 499 | 1845-1848 | Gene | denotes | Ang | Gene:283 |
| 500 | 1628-1673 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
| 501 | 1675-1686 | Species | denotes | SARS-CoV) 2 | Tax:2697049 |
| 502 | 1691-1699 | Species | denotes | SARS-CoV | Tax:694009 |
| 503 | 652-657 | Chemical | denotes | water | MESH:D014867 |
| 504 | 860-865 | Chemical | denotes | water | MESH:D014867 |
| 505 | 941-952 | Disease | denotes | hypertrophy | MESH:D006984 |
| 506 | 954-962 | Disease | denotes | fibrosis | MESH:D005355 |
| 507 | 1799-1808 | Disease | denotes | infection | MESH:D007239 |
| 511 | 83-86 | Gene | denotes | ACE | Gene:1636 |
| 512 | 40-62 | Disease | denotes | cardiovascular disease | MESH:D002318 |
| 513 | 164-187 | Disease | denotes | cardiovascular diseases | MESH:D002318 |