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PMC:7161517 / 9734-19551 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T55 564-580 Body_part denotes zona glomerulosa http://purl.org/sig/ont/fma/fma69225
T56 588-603 Body_part denotes adrenal medulla http://purl.org/sig/ont/fma/fma15633
T57 822-841 Body_part denotes posterior pituitary http://purl.org/sig/ont/fma/fma74636
T58 861-881 Body_part denotes antidiuretic hormone http://purl.org/sig/ont/fma/fma74646
T59 936-943 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T60 1306-1310 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T61 1760-1767 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T62 1818-1825 Body_part denotes cytosol http://purl.org/sig/ont/fma/fma66836
T63 2170-2174 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T64 2182-2204 Body_part denotes peritoneal macrophages http://purl.org/sig/ont/fma/fma83025
T65 2305-2309 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T66 2360-2382 Body_part denotes peritoneal macrophages http://purl.org/sig/ont/fma/fma83025
T67 2409-2416 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T68 2580-2587 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T69 2712-2720 Body_part denotes monocyte http://purl.org/sig/ont/fma/fma62864
T70 2729-2740 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T71 2769-2774 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T72 2928-2932 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T73 3004-3008 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T74 3177-3188 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T75 3515-3522 Body_part denotes adenine http://purl.org/sig/ont/fma/fma82774
T76 3584-3612 Body_part denotes vascular smooth muscle cells http://purl.org/sig/ont/fma/fma284560
T77 3607-3612 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T78 4273-4277 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T79 4308-4323 Body_part denotes thoracic aortas http://purl.org/sig/ont/fma/fma3786
T80 4516-4530 Body_part denotes thoracic aorta http://purl.org/sig/ont/fma/fma3786
T81 4736-4752 Body_part denotes carotid arteries http://purl.org/sig/ont/fma/fma3939
T82 4744-4752 Body_part denotes arteries http://purl.org/sig/ont/fma/fma63812
T83 4841-4845 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T84 4850-4857 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T85 4896-4910 Body_part denotes arterial blood http://purl.org/sig/ont/fma/fma83066
T86 5703-5718 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T87 5862-5868 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T88 5968-5972 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T89 5992-5996 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T90 6301-6311 Body_part denotes myocardium http://purl.org/sig/ont/fma/fma9462
T91 6372-6384 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T92 6372-6376 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T93 6400-6406 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T94 6452-6472 Body_part denotes left coronary artery http://purl.org/sig/ont/fma/fma50040
T95 6509-6515 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T96 6557-6563 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T97 6633-6637 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T98 6719-6729 Body_part denotes myocardium http://purl.org/sig/ont/fma/fma9462
T99 6796-6802 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T100 6839-6845 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T101 7179-7189 Body_part denotes myocardium http://purl.org/sig/ont/fma/fma9462
T102 7478-7482 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T103 7487-7494 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T104 7523-7529 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T105 7611-7619 Body_part denotes collagen http://purl.org/sig/ont/fma/fma63891
T106 7923-7927 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T107 8452-8463 Body_part denotes endothelium http://purl.org/sig/ont/fma/fma63916
T108 8667-8671 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T109 8730-8734 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T110 8854-8860 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T111 8883-8889 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T112 8936-8940 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T113 9074-9078 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122
T114 9614-9618 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520
T115 9753-9757 Body_part denotes axis http://purl.org/sig/ont/fma/fma12520

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T35 76-79 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T36 281-305 Body_part denotes Renin-Angiotensin System http://purl.obolibrary.org/obo/UBERON_0018229
T37 588-603 Body_part denotes adrenal medulla http://purl.obolibrary.org/obo/UBERON_0001236
T38 1367-1391 Body_part denotes renin-angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229
T39 1393-1396 Body_part denotes RAS http://purl.obolibrary.org/obo/UBERON_0018229
T40 2769-2774 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T41 4308-4323 Body_part denotes thoracic aortas http://purl.obolibrary.org/obo/UBERON_0001515
T42 4446-4452 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T43 4516-4530 Body_part denotes thoracic aorta http://purl.obolibrary.org/obo/UBERON_0001515
T44 4525-4530 Body_part denotes aorta http://purl.obolibrary.org/obo/UBERON_0000947
T45 4896-4910 Body_part denotes arterial blood http://purl.obolibrary.org/obo/UBERON_0013755
T46 4905-4910 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T47 5438-5445 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055
T48 5703-5718 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T49 5712-5718 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T50 6301-6311 Body_part denotes myocardium http://purl.obolibrary.org/obo/UBERON_0002349
T51 6452-6472 Body_part denotes left coronary artery http://purl.obolibrary.org/obo/UBERON_0001626
T52 6457-6472 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T53 6466-6472 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T54 6719-6729 Body_part denotes myocardium http://purl.obolibrary.org/obo/UBERON_0002349
T55 7179-7189 Body_part denotes myocardium http://purl.obolibrary.org/obo/UBERON_0002349
T56 8452-8463 Body_part denotes endothelium http://purl.obolibrary.org/obo/UBERON_0001986

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T50 20-42 Disease denotes Cardiovascular Disease http://purl.obolibrary.org/obo/MONDO_0004995
T51 83-105 Disease denotes cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T52 207-230 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T53 323-331 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T54 832-841 Disease denotes pituitary http://purl.obolibrary.org/obo/MONDO_0021156
T55 1505-1508 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T56 1671-1704 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T57 1718-1726 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 1734-1742 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 1842-1851 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T60 2769-2782 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T61 4153-4156 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T62 5122-5125 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T63 5516-5519 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T64 5955-5958 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T65 6002-6023 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T66 6131-6134 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T67 6253-6256 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T68 6486-6507 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T69 6620-6623 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T70 6939-6942 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T71 7015-7036 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T72 7196-7217 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T73 7783-7786 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T74 7969-7972 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840
T75 8575-8578 Disease denotes AT1 http://purl.obolibrary.org/obo/MONDO_0008840

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T106 157-160 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T107 822-831 http://purl.obolibrary.org/obo/UBERON_0001353 denotes posterior
T108 1319-1320 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 1613-1616 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T110 2176-2181 http://purl.obolibrary.org/obo/CLO_0007836 denotes Mouse
T111 2182-2204 http://purl.obolibrary.org/obo/CL_0000581 denotes peritoneal macrophages
T112 2281-2289 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T113 2354-2359 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T114 2360-2382 http://purl.obolibrary.org/obo/CL_0000581 denotes peritoneal macrophages
T115 2706-2711 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T116 2712-2720 http://purl.obolibrary.org/obo/CL_0000576 denotes monocyte
T117 2769-2774 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T118 2769-2774 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T119 2769-2774 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T120 2769-2774 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T121 2894-2902 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T122 2968-2976 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T123 3102-3110 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T124 3165-3173 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T125 3272-3280 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T126 3301-3309 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T127 3500-3501 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 3593-3612 http://purl.obolibrary.org/obo/CL_0000192 denotes smooth muscle cells
T129 3633-3642 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T130 3941-3949 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T131 4127-4134 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T132 4237-4238 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 4308-4323 http://purl.obolibrary.org/obo/UBERON_0001515 denotes thoracic aortas
T134 4308-4323 http://www.ebi.ac.uk/efo/EFO_0002525 denotes thoracic aortas
T135 4446-4452 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
T136 4516-4530 http://purl.obolibrary.org/obo/UBERON_0001515 denotes thoracic aorta
T137 4516-4530 http://www.ebi.ac.uk/efo/EFO_0002525 denotes thoracic aorta
T138 4720-4728 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T139 4736-4752 http://www.ebi.ac.uk/efo/EFO_0000818 denotes carotid arteries
T140 4768-4775 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T141 4841-4845 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T142 4896-4904 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arterial
T143 4896-4904 http://www.ebi.ac.uk/efo/EFO_0000814 denotes arterial
T144 4905-4910 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T145 4905-4910 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T146 5061-5062 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T147 5169-5177 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T148 5246-5250 http://purl.obolibrary.org/obo/PR_000001307 denotes CD44
T149 5281-5283 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T150 5364-5372 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T151 5438-5445 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessels
T152 5572-5580 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T153 5581-5585 http://purl.obolibrary.org/obo/PR_000001307 denotes CD44
T154 5659-5661 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T155 5712-5718 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T156 5712-5718 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T157 5862-5868 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T158 6182-6190 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T159 6301-6311 http://purl.obolibrary.org/obo/UBERON_0002349 denotes myocardium
T160 6372-6376 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T161 6400-6406 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T162 6466-6472 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T163 6466-6472 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T164 6509-6515 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T165 6557-6563 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T166 6719-6729 http://purl.obolibrary.org/obo/UBERON_0002349 denotes myocardium
T167 6796-6802 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T168 6839-6845 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T169 6859-6867 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T170 7060-7061 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T171 7179-7189 http://purl.obolibrary.org/obo/UBERON_0002349 denotes myocardium
T172 7346-7348 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T173 7351-7352 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T174 7523-7529 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T175 7611-7619 http://purl.obolibrary.org/obo/CHEBI_3815 denotes collagen
T176 8452-8463 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T177 8597-8599 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T178 8667-8671 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T179 8748-8756 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T180 8854-8860 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T181 8883-8889 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T182 9126-9127 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T183 9128-9134 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T184 9389-9399 http://purl.obolibrary.org/obo/PR_000001898 denotes neprilysin
T185 9538-9544 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T186 9580-9590 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T187 9787-9788 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T113 76-79 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T114 126-140 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T115 130-140 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T116 287-298 Chemical denotes Angiotensin http://purl.obolibrary.org/obo/CHEBI_2719
T117 342-353 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T118 384-386 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T119 391-402 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T120 456-470 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T121 460-470 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T122 508-510 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T123 619-630 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T125 656-673 Chemical denotes mineralocorticoid http://purl.obolibrary.org/obo/CHEBI_25354
T126 695-700 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T127 730-734 Chemical denotes salt http://purl.obolibrary.org/obo/CHEBI_24866|http://purl.obolibrary.org/obo/CHEBI_26710
T129 765-782 Chemical denotes mineralocorticoid http://purl.obolibrary.org/obo/CHEBI_25354
T130 792-803 Chemical denotes antagonists http://purl.obolibrary.org/obo/CHEBI_48706
T131 847-849 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T132 874-881 Chemical denotes hormone http://purl.obolibrary.org/obo/CHEBI_24621
T133 903-908 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T134 1072-1083 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T135 1126-1128 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T136 1150-1152 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T137 1178-1189 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T138 1373-1384 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T139 1393-1396 Chemical denotes RAS http://purl.obolibrary.org/obo/CHEBI_63620
T140 1430-1432 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T141 1582-1584 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T142 1760-1767 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T143 1892-1894 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T144 2116-2120 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T145 2227-2238 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T147 2396-2439 Chemical denotes nicotinamide adenine dinucleotide phosphate http://purl.obolibrary.org/obo/CHEBI_18009|http://purl.obolibrary.org/obo/CHEBI_25523
T149 2396-2408 Chemical denotes nicotinamide http://purl.obolibrary.org/obo/CHEBI_17154
T150 2409-2416 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T151 2417-2429 Chemical denotes dinucleotide http://purl.obolibrary.org/obo/CHEBI_47885
T152 2430-2439 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T156 2448-2457 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T157 2459-2470 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T159 2567-2610 Chemical denotes nicotinamide adenine dinucleotide phosphate http://purl.obolibrary.org/obo/CHEBI_18009|http://purl.obolibrary.org/obo/CHEBI_25523
T161 2567-2579 Chemical denotes nicotinamide http://purl.obolibrary.org/obo/CHEBI_17154
T162 2580-2587 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T163 2588-2600 Chemical denotes dinucleotide http://purl.obolibrary.org/obo/CHEBI_47885
T164 2601-2610 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T168 2688-2698 Chemical denotes eplerenone http://purl.obolibrary.org/obo/CHEBI_31547
T169 2839-2853 Chemical denotes spironolactone http://purl.obolibrary.org/obo/CHEBI_9241
T170 3077-3087 Chemical denotes eplerenone http://purl.obolibrary.org/obo/CHEBI_31547
T171 3438-3440 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T172 3451-3462 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T174 3502-3545 Chemical denotes nicotinamide adenine dinucleotide phosphate http://purl.obolibrary.org/obo/CHEBI_18009|http://purl.obolibrary.org/obo/CHEBI_25523
T176 3502-3514 Chemical denotes nicotinamide http://purl.obolibrary.org/obo/CHEBI_17154
T177 3515-3522 Chemical denotes adenine http://purl.obolibrary.org/obo/CHEBI_16708
T178 3523-3535 Chemical denotes dinucleotide http://purl.obolibrary.org/obo/CHEBI_47885
T179 3536-3545 Chemical denotes phosphate http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474
T183 3630-3632 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T184 3730-3753 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T185 3739-3745 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T186 4009-4011 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T187 4213-4223 Chemical denotes olmesartan http://purl.obolibrary.org/obo/CHEBI_48416
T188 4352-4360 Chemical denotes atenolol http://purl.obolibrary.org/obo/CHEBI_2904|http://purl.obolibrary.org/obo/CHEBI_55352
T190 4365-4376 Chemical denotes hydralazine http://purl.obolibrary.org/obo/CHEBI_5775
T191 4481-4491 Chemical denotes olmesartan http://purl.obolibrary.org/obo/CHEBI_48416
T192 4637-4645 Chemical denotes atenolol http://purl.obolibrary.org/obo/CHEBI_2904|http://purl.obolibrary.org/obo/CHEBI_55352
T194 4649-4660 Chemical denotes hydralazine http://purl.obolibrary.org/obo/CHEBI_5775
T195 4813-4823 Chemical denotes olmesartan http://purl.obolibrary.org/obo/CHEBI_48416
T196 4850-4857 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T197 4998-5006 Chemical denotes atenolol http://purl.obolibrary.org/obo/CHEBI_2904|http://purl.obolibrary.org/obo/CHEBI_55352
T199 5010-5021 Chemical denotes hydralazine http://purl.obolibrary.org/obo/CHEBI_5775
T200 5084-5086 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T201 5107-5109 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T202 5191-5203 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T203 5198-5203 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T205 5313-5324 Chemical denotes telmisartan http://purl.obolibrary.org/obo/CHEBI_9434
T206 5389-5401 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T207 5396-5401 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T209 5545-5556 Chemical denotes telmisartan http://purl.obolibrary.org/obo/CHEBI_9434
T210 5811-5819 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T211 5824-5834 Chemical denotes olmesartan http://purl.obolibrary.org/obo/CHEBI_48416
T212 6520-6522 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T213 6751-6759 Chemical denotes ramipril http://purl.obolibrary.org/obo/CHEBI_8774
T214 6764-6773 Chemical denotes valsartan http://purl.obolibrary.org/obo/CHEBI_9927
T215 6817-6819 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T216 7234-7242 Chemical denotes ramipril http://purl.obolibrary.org/obo/CHEBI_8774
T217 7424-7434 Chemical denotes olmesartan http://purl.obolibrary.org/obo/CHEBI_48416
T218 7438-7449 Chemical denotes telmisartan http://purl.obolibrary.org/obo/CHEBI_9434
T219 7487-7494 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T220 7541-7543 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T221 7676-7690 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T222 7680-7690 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T223 7773-7775 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T224 7829-7831 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T225 8067-8069 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T226 8095-8109 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T227 8099-8109 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T228 8161-8175 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T229 8165-8175 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T230 8280-8294 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T231 8284-8294 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T232 8334-8336 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T233 8367-8377 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T234 8431-8441 Chemical denotes bradykinin http://purl.obolibrary.org/obo/CHEBI_3165
T235 8505-8518 Chemical denotes prostaglandin http://purl.obolibrary.org/obo/CHEBI_26333
T236 8523-8535 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T237 8530-8535 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T239 8702-8704 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T240 8816-8824 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T241 8894-8896 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T242 8969-8977 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T243 9006-9014 Chemical denotes losartan http://purl.obolibrary.org/obo/CHEBI_6541
T244 9019-9029 Chemical denotes lisinopril http://purl.obolibrary.org/obo/CHEBI_43755
T245 9096-9110 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T246 9100-9110 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T247 9188-9190 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T248 9367-9371 Chemical denotes zinc http://purl.obolibrary.org/obo/CHEBI_27363|http://purl.obolibrary.org/obo/CHEBI_30185
T250 9481-9495 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T251 9485-9495 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T36 5-15 http://purl.obolibrary.org/obo/GO_0065007 denotes Regulation
T37 111-121 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T38 619-640 http://purl.obolibrary.org/obo/GO_0035932 denotes aldosterone secretion
T39 631-640 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T40 735-744 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T41 874-891 http://purl.obolibrary.org/obo/GO_0046879 denotes hormone secretion
T42 882-891 http://purl.obolibrary.org/obo/GO_0046903 denotes secretion
T43 909-918 http://purl.obolibrary.org/obo/GO_0051235 denotes retention
T44 1029-1038 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T45 1029-1038 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T46 1492-1503 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T47 1798-1817 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into the host
T48 1856-1873 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T49 1856-1873 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T50 3421-3430 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T51 3478-3491 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T52 3633-3642 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T53 3658-3673 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T54 3677-3681 http://purl.obolibrary.org/obo/GO_0004707 denotes ERK1
T55 3730-3764 http://purl.obolibrary.org/obo/GO_1903409 denotes reactive oxygen species generation
T56 5622-5628 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T57 7748-7765 http://purl.obolibrary.org/obo/GO_0051100 denotes inhibited binding
T58 8474-8486 http://purl.obolibrary.org/obo/GO_0042311 denotes vasodilation
T59 8557-8567 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T60 8705-8714 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T61 9155-9168 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T67 0-42 Sentence denotes ACE2 Regulation and Cardiovascular Disease
T68 43-255 Sentence denotes Because of the importance of the RAS in cardiovascular disease, its regulation via ACE inhibitors, ARBs, and MRAs has played an essential role in the management of cardiovascular diseases (Central Illustration ).
T69 256-331 Sentence denotes Central Illustration The Renin-Angiotensin System Interaction With COVID-19
T70 332-471 Sentence denotes Normally, angiotensin I (Ang I) is converted to Ang II via angiotensin-converting enzyme (ACE), which could be inhibited by ACE inhibitors.
T71 472-553 Sentence denotes The pro-inflammatory effects of Ang II are mediated through AT1R in several ways:
T72 554-1039 Sentence denotes 1) in the zona glomerulosa of the adrenal medulla, it stimulates aldosterone secretion and binding to mineralocorticoid receptors to promote water reabsorption and to increase salt retention; it is inhibited by mineralocorticoid receptor antagonists (MRAs); 2) in the posterior pituitary, Ang II stimulates antidiuretic hormone secretion to promote water retention; and 3) in other tissues, it stimulates pathways responsible for hypertrophy, fibrosis, oxidative stress, and apoptosis.
T73 1040-1145 Sentence denotes These effects are attenuated by angiotensin receptor blockers (ARBs), which block Ang II binding to AT1R.
T74 1146-1285 Sentence denotes Ang II can also be converted to angiotensin 1-7 (Ang 1-7) via ACE2, which stimulates the Mas receptor promoting anti-inflammatory benefits.
T75 1286-1398 Sentence denotes The ACE2/Ang1-7/Mas axis acts as a counter regulatory pathway to the traditional renin-angiotensin system (RAS).
T76 1399-1425 Sentence denotes AT1R and ACE2 are coupled.
T77 1426-1504 Sentence denotes Ang II binding to AT1R allows dissociation of ACE2 and subsequent degradation.
T78 1505-1607 Sentence denotes ARB prevents dissociation of ACE2 and renders it availability for unused Ang II conversion to Ang 1-7.
T79 1608-1743 Sentence denotes ACE2 has been identified as the targeted receptor for both the severe acute respiratory syndrome coronavirus (SARS-CoV) 2 and SARS-CoV.
T80 1744-1874 Sentence denotes ACE2 mediates S protein binding that stimulates viral entry into the host cytosol that results in infection and viral replication.
T81 1875-2065 Sentence denotes Diversion of Ang II towards ACE2 could competitively inhibit viral binding and also counter regulate the adverse effects caused by AT1R and improve outcomes by Mas R−based favorable effects.
T82 2066-2175 Sentence denotes Several studies have elucidated the role of these drug classes on the modulation of the ACE2/Ang1-7/Mas axis.
T83 2176-2341 Sentence denotes Mouse peritoneal macrophages treated in vitro with aldosterone, demonstrated significantly increased ACE activity as well as ACE mRNA and significantly reduced ACE2.
T84 2342-2624 Sentence denotes However, in mouse peritoneal macrophages treated with nicotinamide adenine dinucleotide phosphate oxidase inhibitor, aldosterone could not increase ACE or decrease ACE2, which suggested these effects were mediated in part by nicotinamide adenine dinucleotide phosphate oxidase (42).
T85 2625-2705 Sentence denotes These effects were also attenuated with treatment with an MRA (eplerenone) (42).
T86 2706-2944 Sentence denotes Human monocyte-derived macrophages obtained from patients with heart failure before and after 1 month of treatment with another MRA (spironolactone; 25 mg/day) showed 47% reduction in ACE activity and 53% reduction in ACE mRNA expression.
T87 2945-3043 Sentence denotes At the same time, ACE2 activity increased by 300% and ACE2 mRNA expression increased by 654% (42).
T88 3044-3194 Sentence denotes In mice treated for 2 weeks with eplerenone, cardiac ACE2 activity increased 2-fold and was paralleled by increased ACE2 activity in macrophages (42).
T89 3195-3441 Sentence denotes This study demonstrated that the MRA reduced oxidative stress, decreased ACE activity, and increased ACE2 activity and/or expression, which suggested the protective role played by increased generation of Ang 1-7 and decreased formation of Ang II.
T90 3442-3770 Sentence denotes Overall, aldosterone decreased ACE2 transcription through a nicotinamide adenine dinucleotide phosphate oxidase−mediated pathway (42), and in vascular smooth muscle cells, potentiated Ang II signaling with increased phosphorylation of ERK1/2 and c-Jun kinase, which are also dependent on reactive oxygen species generation (43).
T91 3771-3915 Sentence denotes Thus, the beneficial effects of MRAs are likely associated with reduction of oxidative stress and differential control of these angiotensinases.
T92 3916-4073 Sentence denotes MRAs appeared to promote membrane ACE2 expression and suppress the peripheral effects of Ang II; however, the effect of MRAs on soluble ACE2 remains unclear.
T93 4074-4167 Sentence denotes Similar upregulation of ACE2 was observed in studies focused on the effects of ARB treatment.
T94 4168-4431 Sentence denotes Spontaneously hypertensive rats treated with olmesartan demonstrated a 5-fold greater expression of ACE2 mRNA and increased Ang1-7 in their thoracic aortas, whereas those treated with atenolol and hydralazine exhibited no change in ACE2 expression or Ang1-7 (44).
T95 4432-4666 Sentence denotes Comparison of vessel wall dimensions showed that olmesartan selectively reduced the thoracic aorta media-to-lumen ratio, whereas vascular hypertrophy was unchanged in spontaneously hypertensive rats given atenolol or hydralazine (44).
T96 4667-4776 Sentence denotes There was no change in ACE2/Ang1-7 expression and/or activity in the carotid arteries of the treated animals.
T97 4777-5027 Sentence denotes The possibility that the effects of olmesartan on vascular ACE2 gene and protein expression were the result of reduced arterial blood pressure was ruled out because of the comparative effect observed in mice treated with atenolol or hydralazine (44).
T98 5028-5285 Sentence denotes Sprague-Dawley rats treated with a 4-week course of Ang II infusion showed Ang II upregulated AT1 receptor, downregulated AT2 receptor, ACE2 activity, endothelial nitric oxide synthase expression, as well as increased CD44 expression and hyaluronidase (45).
T99 5286-5529 Sentence denotes However, rats treated with telmisartan exhibited significantly increased ACE2 activity and endothelial nitric oxide synthase expression in intracardiac vessels and intermyocardium, as well as downregulated local expression of the AT1 receptor.
T100 5530-5663 Sentence denotes Treatment with telmisartan also inhibited membrane CD44 expression and reduced transforming growth factor−β and Smad expression (45).
T101 5664-5909 Sentence denotes Studies in normotensive rats with post-coronary artery ligation left ventricular remodeling and dysfunction exhibited partial resolution following losartan and olmesartan treatment while augmenting plasma concentrations of the angiotensins (46).
T102 5910-6196 Sentence denotes This was associated with recovery of cardiac AT1 receptor mRNA and increased ACE2 mRNA post-myocardial infarction, which implied the beneficial effects of ARBs on cardiac remodeling were accompanied by direct blockade of AT1 receptors and increased ACE2 expression and/or activity (46).
T103 6197-6419 Sentence denotes The literature offers conflicting results pertaining to ARB use and the level of ACE2 expression on the myocardium; most of the controversy arises from the difference in ACE2 cell surface expression and plasma ACE2 levels.
T104 6420-6665 Sentence denotes In the Sprague-Dawley rats with left coronary artery ligation and myocardial infarction, plasma Ang II and Ang1-7 were not elevated, but plasma ACE2 was elevated, along with enhanced cardiac ACE2 and AT1 receptor mRNA at the infarct border (47).
T105 6666-6735 Sentence denotes Receptor upregulation was not observed in the remote myocardium (47).
T106 6736-7050 Sentence denotes Treatment with ramipril and valsartan resulted in increased plasma Ang I and Ang II and suppression in plasma ACE and ACE2 activity; however, neither monotherapy nor combination therapy affected ACE2 or AT1 receptor expression, both of which remained at levels comparable to non-myocardial infarction control (47).
T107 7051-7218 Sentence denotes However, a previous study in the same murine model showed ACE and ACE2 upregulation in the border, infarct zones, and in viable myocardium after myocardial infarction.
T108 7219-7350 Sentence denotes Treatment with ramipril reduced ACE expression, whereas ACE2 remained elevated compared with the noninfarcted control subject (48).
T109 7351-7637 Sentence denotes A recent study in the same murine model demonstrated that treatment with olmesartan or telmisartan increased both cardiac ACE2 mRNA and protein expression while augmenting plasma Ang1-7/Ang II ratios, which resulted in improved cardiac function and alleviated collagen disposition (49).
T110 7638-7742 Sentence denotes These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49).
T111 7743-7879 Sentence denotes ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shunted to ACE2 for conversion to Ang1-7.
T112 7880-8070 Sentence denotes These studies suggest that the ACE2/Ang1-7 axis collaborates with or is regulated by the AT1 receptor and may be important in mediating the vascular and cardiac remodeling effects of Ang II.
T113 8071-8126 Sentence denotes The mechanisms by which ACE inhibitors act are complex.
T114 8127-8279 Sentence denotes Although ACE2 is not inhibited by ACE inhibitors (19), an increase in Ang1-7 suggests their clinical effects are partly mediated by the angiotensinases.
T115 8280-8378 Sentence denotes ACE inhibitors inhibit the conversion of Ang I to Ang II and inhibit the hydrolysis of bradykinin.
T116 8379-8601 Sentence denotes ACE inhibition promotes the vasodilatory effects of bradykinin, improved endothelium-dependent vasodilation through increased prostaglandin and nitric oxide production, and down regulation of the AT1 receptor (50, 51, 52).
T117 8602-8762 Sentence denotes Studies that elucidated the effect of ACE inhibition on the ACE2 gene showed that inhibition of Ang II synthesis regulated ACE2 mRNA but not ACE2 activity (53).
T118 8763-8902 Sentence denotes However, ACE inhibition alone or in combination with losartan was demonstrated to increase plasma Ang1-7 while reducing plasma Ang II (53).
T119 8903-9174 Sentence denotes Compared with the degree of ACE2 mRNA upregulation seen with post-losartan monotherapy, combination of losartan and lisinopril resulted in suppressed upregulation of ACE2 mRNA, which suggested ACE inhibitors might override a signal that regulates ACE2 transcription (53).
T120 9175-9456 Sentence denotes Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline.
T121 9457-9619 Sentence denotes Thus, it can be assumed ACE inhibitors disrupt the balance between catalytically active ACE and ACE2, resulting in favored activation of the ACE2/Ang1-7/Mas axis.
T122 9620-9817 Sentence denotes Overall, because of the demonstrated anti-inflammatory, antifibrotic, and antithrombotic effects associated with the ACE2/Ang1-7/Mas axis, upregulation could serve as a valuable therapeutic target.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T9 20-42 Phenotype denotes Cardiovascular Disease http://purl.obolibrary.org/obo/HP_0001626
T10 83-105 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T11 207-230 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T12 903-918 Phenotype denotes water retention http://purl.obolibrary.org/obo/HP_0000969
T13 1007-1023 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T14 2769-2782 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T15 3240-3256 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T16 3848-3864 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T17 6002-6023 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T18 6486-6507 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T19 7015-7036 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T20 7196-7217 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T345 0-4 G_3;PG_10;PR:000003622 denotes ACE2
T346 5-15 GO:0065007 denotes Regulation
T347 20-34 UBERON:0004535 denotes Cardiovascular
T348 83-97 UBERON:0004535 denotes cardiovascular
T349 111-121 GO:0065007 denotes regulation
T350 130-140 CHEBI:35222;CHEBI:35222 denotes inhibitors
T351 207-221 UBERON:0004535 denotes cardiovascular
T352 281-286 PR:000013883 denotes Renin
T353 323-340 SP_7 denotes COVID-19 Normally
T354 342-355 PR:000036008 denotes angiotensin I
T355 357-362 PR:000036008 denotes Ang I
T356 380-386 PR:000036009 denotes Ang II
T357 460-470 CHEBI:35222;CHEBI:35222 denotes inhibitors
T358 504-510 PR:000036009 denotes Ang II
T359 532-536 PR:000001251 denotes AT1R
T360 564-580 UBERON:0002053 denotes zona glomerulosa
T361 588-603 UBERON:0001236 denotes adrenal medulla
T362 619-630 CHEBI:27584;CHEBI:27584 denotes aldosterone
T363 656-673 CHEBI:25354;CHEBI:25354 denotes mineralocorticoid
T364 695-700 CHEBI:15377;CHEBI:15377 denotes water
T365 730-734 CHEBI:24866;CHEBI:24866 denotes salt
T366 765-782 CHEBI:25354;CHEBI:25354 denotes mineralocorticoid
T367 783-803 CHEBI:48561;CHEBI:48561 denotes receptor antagonists
T368 832-841 UBERON:0002198 denotes pituitary
T369 843-849 PR:000036009 denotes Ang II
T370 903-908 CHEBI:15377;CHEBI:15377 denotes water
T371 936-943 UBERON:0000479 denotes tissues
T372 1007-1016 MOP:0000568 denotes oxidative
T373 1029-1038 GO:0006915 denotes apoptosis
T374 1122-1125 CHEBI:37886;CHEBI:37886;PR:000036009 denotes Ang
T375 1126-1128 PR:000036009 denotes II
T376 1140-1144 PR:000001251 denotes AT1R
T377 1146-1152 PR:000036009 denotes Ang II
T378 1178-1191 PR:000036013 denotes angiotensin 1
T379 1195-1200 PR:000036013 denotes Ang 1
T380 1208-1212 PR:000003622;G_3;PG_10 denotes ACE2
T381 1235-1238 PR:000001563 denotes Mas
T382 1290-1294 G_3;PG_10;PR:000003622 denotes ACE2
T383 1295-1299 PR:000036013 denotes Ang1
T384 1367-1372 PR:000013883 denotes renin
T385 1399-1403 PR:000001251 denotes AT1R
T386 1408-1412 PR:000003622;G_3;PG_10 denotes ACE2
T387 1426-1432 PR:000036009 denotes Ang II
T388 1444-1448 PR:000001251 denotes AT1R
T389 1472-1476 PR:000003622;G_3;PG_10 denotes ACE2
T390 1534-1538 G_3;PG_10;PR:000003622 denotes ACE2
T391 1578-1584 PR:000036009 denotes Ang II
T392 1599-1604 PR:000036013 denotes Ang 1
T393 1608-1612 G_3;PG_10;PR:000003622 denotes ACE2
T394 1671-1683 SP_10 denotes severe acute
T395 1684-1695 SP_10;UBERON:0001004 denotes respiratory
T396 1696-1716 SP_10 denotes syndrome coronavirus
T397 1718-1726 SP_10 denotes SARS-CoV
T398 1734-1742 SP_10 denotes SARS-CoV
T399 1744-1748 G_3;PG_10;PR:000003622 denotes ACE2
T400 1758-1767 PG_1 denotes S protein
T401 1792-1797 NCBITaxon:10239;GO:0035376 denotes viral
T402 1798-1803 GO:0035376 denotes entry
T403 1813-1825 GO:0044164 denotes host cytosol
T404 1856-1861 NCBITaxon:10239;GO:0006260 denotes viral
T405 1862-1873 GO:0006260 denotes replication
T406 1888-1894 PR:000036009 denotes Ang II
T407 1903-1907 PR:000003622;G_3;PG_10 denotes ACE2
T408 1936-1941 NCBITaxon:10239 denotes viral
T409 2006-2010 PR:000001251 denotes AT1R
T410 2035-2040 PR:000001607 denotes Mas R
T468 2116-2120 CHEBI:23888;CHEBI:23888 denotes drug
T469 2136-2146 GO:0065007 denotes modulation
T470 2154-2158 G_3;PG_10;PR:000003622 denotes ACE2
T471 2159-2163 PR:000036013 denotes Ang1
T472 2176-2181 NCBITaxon:10088 denotes Mouse
T473 2182-2192 UBERON:0001179;CL:0000581 denotes peritoneal
T474 2193-2204 CL:0000581 denotes macrophages
T475 2227-2238 CHEBI:27584;CHEBI:27584 denotes aldosterone
T476 2336-2340 G_3;PG_10;PR:000003622 denotes ACE2
T477 2354-2359 NCBITaxon:10088 denotes mouse
T478 2360-2370 UBERON:0001179;CL:0000581 denotes peritoneal
T479 2371-2382 CL:0000581 denotes macrophages
T480 2396-2408 CHEBI:17154;CHEBI:17154 denotes nicotinamide
T481 2430-2439 CHEBI:18367;CHEBI:18367 denotes phosphate
T482 2448-2457 CHEBI:35222;CHEBI:35222 denotes inhibitor
T483 2459-2470 CHEBI:27584;CHEBI:27584 denotes aldosterone
T484 2506-2510 G_3;PG_10;PR:000003622 denotes ACE2
T485 2567-2579 CHEBI:17154;CHEBI:17154 denotes nicotinamide
T486 2688-2698 CHEBI:31547;CHEBI:31547 denotes eplerenone
T487 2706-2711 SP_6;NCBITaxon:9606 denotes Human
T488 2712-2720 CL:0000576 denotes monocyte
T489 2729-2740 CL:0000235 denotes macrophages
T490 2769-2774 UBERON:0000948 denotes heart
T491 2839-2853 CHEBI:9241;CHEBI:9241 denotes spironolactone
T492 2933-2943 GO:0010467 denotes expression
T493 2963-2967 G_3;PG_10;PR:000003622 denotes ACE2
T494 2999-3003 G_3;PG_10;PR:000003622 denotes ACE2
T495 3009-3019 GO:0010467 denotes expression
T496 3047-3051 NCBITaxon:10088 denotes mice
T497 3077-3087 CHEBI:31547;CHEBI:31547 denotes eplerenone
T498 3089-3096 UBERON:0000948 denotes cardiac
T499 3097-3101 G_3;PG_10;PR:000003622 denotes ACE2
T500 3160-3164 G_3;PG_10;PR:000003622 denotes ACE2
T501 3177-3188 CL:0000235 denotes macrophages
T502 3240-3249 MOP:0000568 denotes oxidative
T503 3296-3300 G_3;PG_10;PR:000003622 denotes ACE2
T504 3317-3327 GO:0010467 denotes expression
T505 3399-3404 PR:000036013 denotes Ang 1
T506 3434-3440 PR:000036009 denotes Ang II
T507 3451-3462 CHEBI:27584;CHEBI:27584 denotes aldosterone
T508 3473-3477 G_3;PG_10;PR:000003622 denotes ACE2
T509 3502-3514 CHEBI:17154;CHEBI:17154 denotes nicotinamide
T510 3536-3545 CHEBI:18367;CHEBI:18367 denotes phosphate
T511 3584-3592 CL:0000359 denotes vascular
T512 3593-3606 CL:0000359;UBERON:0004237 denotes smooth muscle
T513 3607-3612 CL:0000359 denotes cells
T514 3626-3632 PR:000036009 denotes Ang II
T515 3677-3681 PR:000000104 denotes ERK1
T516 3690-3693 PR:000009232 denotes Jun
T517 3730-3753 CHEBI:70982;CHEBI:70982 denotes reactive oxygen species
T518 3848-3857 MOP:0000568 denotes oxidative
T519 3882-3889 GO:0065007 denotes control
T520 3941-3949 GO:0016020 denotes membrane
T521 3950-3954 G_3;PG_10;PR:000003622 denotes ACE2
T522 3955-3965 GO:0010467 denotes expression
T523 4005-4011 PR:000036009 denotes Ang II
T524 4052-4056 G_3;PG_10;PR:000003622 denotes ACE2
T525 4098-4102 G_3;PG_10;PR:000003622 denotes ACE2
T526 4195-4199 NCBITaxon:10114 denotes rats
T527 4213-4223 CHEBI:48416;CHEBI:48416 denotes olmesartan
T528 4254-4264 GO:0010467 denotes expression
T529 4268-4272 G_3;PG_10;PR:000003622 denotes ACE2
T530 4292-4296 PR:000036013 denotes Ang1
T531 4308-4323 UBERON:0001515 denotes thoracic aortas
T532 4352-4360 CHEBI:2904;CHEBI:2904 denotes atenolol
T533 4365-4376 CHEBI:5775;CHEBI:5775 denotes hydralazine
T534 4400-4404 G_3;PG_10;PR:000003622 denotes ACE2
T535 4405-4415 GO:0010467 denotes expression
T536 4419-4423 PR:000036013 denotes Ang1
T537 4446-4452 UBERON:0000055 denotes vessel
T538 4453-4457 UBERON:0000060 denotes wall
T539 4516-4530 UBERON:0001515 denotes thoracic aorta
T540 4531-4536 UBERON:0004363 denotes media
T541 4626-4630 NCBITaxon:10114 denotes rats
T542 4637-4645 CHEBI:2904;CHEBI:2904 denotes atenolol
T543 4649-4660 CHEBI:5775;CHEBI:5775 denotes hydralazine
T544 4690-4694 G_3;PG_10;PR:000003622 denotes ACE2
T545 4695-4699 PR:000036013 denotes Ang1
T546 4702-4712 GO:0010467 denotes expression
T547 4736-4752 UBERON:0005396 denotes carotid arteries
T548 4768-4775 NCBITaxon:33208 denotes animals
T549 4836-4840 G_3;PG_10;PR:000003622 denotes ACE2
T550 4841-4845 SO:0000704;GO:0010467 denotes gene
T551 4850-4857 BV_20 denotes protein
T552 4858-4868 BV_20;GO:0010467 denotes expression
T553 4896-4910 UBERON:0013755 denotes arterial blood
T554 4980-4984 NCBITaxon:10088 denotes mice
T555 4998-5006 CHEBI:2904;CHEBI:2904 denotes atenolol
T556 5010-5021 CHEBI:5775;CHEBI:5775 denotes hydralazine
T557 5043-5047 NCBITaxon:10114 denotes rats
T558 5080-5083 CHEBI:37886;CHEBI:37886;PR:000036009 denotes Ang
T559 5084-5086 PR:000036009 denotes II
T560 5103-5106 CHEBI:37886;CHEBI:37886;PR:000036009 denotes Ang
T561 5107-5109 PR:000036009 denotes II
T562 5122-5125 PR:000001251 denotes AT1
T563 5150-5153 PR:000001191 denotes AT2
T564 5164-5168 PR:000003622;G_3;PG_10 denotes ACE2
T565 5179-5190 UBERON:0001986 denotes endothelial
T566 5191-5203 CHEBI:16480;CHEBI:16480 denotes nitric oxide
T567 5213-5223 GO:0010467 denotes expression
T568 5246-5250 PR:000001307 denotes CD44
T569 5251-5261 GO:0010467 denotes expression
T570 5295-5299 NCBITaxon:10114 denotes rats
T571 5313-5324 CHEBI:9434;CHEBI:9434 denotes telmisartan
T572 5359-5363 G_3;PG_10;PR:000003622 denotes ACE2
T573 5377-5388 UBERON:0001986 denotes endothelial
T574 5389-5401 CHEBI:16480;CHEBI:16480 denotes nitric oxide
T575 5411-5421 GO:0010467 denotes expression
T576 5425-5437 UBERON:0000948 denotes intracardiac
T577 5438-5445 UBERON:0000055 denotes vessels
T578 5450-5465 UBERON:0002349 denotes intermyocardium
T579 5498-5508 GO:0010467 denotes expression
T580 5516-5519 PR:000001251 denotes AT1
T581 5545-5556 CHEBI:9434;CHEBI:9434 denotes telmisartan
T582 5572-5580 GO:0016020 denotes membrane
T583 5581-5585 PR:000001307 denotes CD44
T584 5586-5596 GO:0010467 denotes expression
T585 5609-5637 PR:000000046 denotes transforming growth factor−β
T586 5647-5657 GO:0010467 denotes expression
T587 5688-5692 NCBITaxon:10114 denotes rats
T588 5703-5718 UBERON:0001621 denotes coronary artery
T589 5728-5744 UBERON:0002084 denotes left ventricular
T590 5811-5819 CHEBI:4670;CHEBI:4670 denotes losartan
T591 5862-5868 UBERON:0001969 denotes plasma
T592 5947-5954 UBERON:0000948 denotes cardiac
T593 5955-5958 PR:000001251 denotes AT1
T594 5987-5991 PR:000003622;G_3;PG_10 denotes ACE2
T595 6002-6012 UBERON:0002349 denotes myocardial
T596 6073-6080 UBERON:0000948 denotes cardiac
T597 6131-6134 PR:000001251 denotes AT1
T598 6159-6163 PR:000003622;G_3;PG_10 denotes ACE2
T599 6164-6174 GO:0010467 denotes expression
T600 6278-6282 G_3;PG_10;PR:000003622 denotes ACE2
T601 6283-6293 GO:0010467 denotes expression
T602 6301-6311 UBERON:0002349 denotes myocardium
T603 6367-6371 G_3;PG_10;PR:000003622 denotes ACE2
T604 6377-6384 GO:0009986 denotes surface
T605 6385-6395 GO:0010467 denotes expression
T606 6400-6406 UBERON:0001969 denotes plasma
T607 6407-6411 G_3;PG_10;PR:000003622 denotes ACE2
T608 6442-6446 NCBITaxon:10114 denotes rats
T609 6452-6456 UBERON:0001652 denotes left
T610 6457-6472 UBERON:0001626 denotes coronary artery
T611 6486-6496 UBERON:0002349 denotes myocardial
T612 6509-6515 UBERON:0001969 denotes plasma
T613 6516-6522 PR:000036009 denotes Ang II
T614 6557-6563 UBERON:0001969 denotes plasma
T615 6564-6568 PR:000003622;G_3;PG_10 denotes ACE2
T616 6603-6610 UBERON:0000948 denotes cardiac
T617 6611-6615 PR:000003622;G_3;PG_10 denotes ACE2
T618 6620-6623 PR:000001251 denotes AT1
T619 6719-6729 UBERON:0002349 denotes myocardium
T620 6751-6759 CHEBI:8774;CHEBI:8774 denotes ramipril
T621 6796-6802 UBERON:0001969 denotes plasma
T622 6803-6806 CHEBI:29101;CHEBI:29101;PR:000036008 denotes Ang
T623 6807-6808 PR:000036008;CHEBI:16382;CHEBI:16382 denotes I
T624 6813-6819 PR:000036009 denotes Ang II
T625 6839-6845 UBERON:0001969 denotes plasma
T626 6854-6858 PR:000003622;G_3;PG_10 denotes ACE2
T627 6931-6935 PR:000003622;G_3;PG_10 denotes ACE2
T628 6939-6942 PR:000001251 denotes AT1
T629 6952-6962 GO:0010467 denotes expression
T630 7015-7025 UBERON:0002349 denotes myocardial
T631 7089-7095 NCBITaxon:39107 denotes murine
T632 7117-7121 G_3;PG_10;PR:000003622 denotes ACE2
T633 7179-7189 UBERON:0002349 denotes myocardium
T634 7196-7206 UBERON:0002349 denotes myocardial
T635 7234-7242 CHEBI:8774;CHEBI:8774 denotes ramipril
T636 7255-7265 GO:0010467 denotes expression
T637 7275-7279 G_3;PG_10;PR:000003622 denotes ACE2
T638 7378-7384 NCBITaxon:39107 denotes murine
T639 7424-7434 CHEBI:48416;CHEBI:48416 denotes olmesartan
T640 7438-7449 CHEBI:9434;CHEBI:9434 denotes telmisartan
T641 7465-7472 UBERON:0000948 denotes cardiac
T642 7473-7477 G_3;PG_10;PR:000003622 denotes ACE2
T643 7487-7494 BV_20 denotes protein
T644 7495-7505 BV_20;GO:0010467 denotes expression
T645 7523-7529 UBERON:0001969 denotes plasma
T646 7530-7534 PR:000036013 denotes Ang1
T647 7579-7586 UBERON:0000948 denotes cardiac
T648 7680-7690 CHEBI:35222;CHEBI:35222 denotes inhibitors
T649 7721-7725 G_3;PG_10;PR:000003622 denotes ACE2
T650 7726-7736 GO:0010467 denotes expression
T651 7769-7772 CHEBI:37886;CHEBI:37886;PR:000036009 denotes Ang
T652 7773-7775 PR:000036009 denotes II
T653 7825-7831 PR:000036009 denotes Ang II
T654 7849-7853 PR:000003622;G_3;PG_10 denotes ACE2
T655 7872-7876 PR:000036013 denotes Ang1
T656 7911-7915 G_3;PG_10;PR:000003622 denotes ACE2
T657 7916-7920 PR:000036013 denotes Ang1
T658 7952-7961 GO:0065007 denotes regulated
T659 7969-7972 PR:000001251 denotes AT1
T660 8033-8040 UBERON:0000948 denotes cardiac
T661 8063-8069 PR:000036009 denotes Ang II
T662 8099-8109 CHEBI:35222;CHEBI:35222 denotes inhibitors
T663 8136-8140 G_3;PG_10;PR:000003622 denotes ACE2
T664 8165-8175 CHEBI:35222;CHEBI:35222 denotes inhibitors
T665 8197-8201 PR:000036013 denotes Ang1
T666 8284-8294 CHEBI:35222;CHEBI:35222 denotes inhibitors
T667 8321-8324 PR:000036008 denotes Ang
T668 8325-8326 PR:000036008;CHEBI:16382;CHEBI:16382 denotes I
T669 8330-8333 CHEBI:37886;CHEBI:37886;PR:000036009 denotes Ang
T670 8334-8336 PR:000036009 denotes II
T671 8353-8363 MOP:0000619 denotes hydrolysis
T672 8367-8377 CHEBI:3165;CHEBI:3165 denotes bradykinin
T673 8431-8441 CHEBI:3165;CHEBI:3165 denotes bradykinin
T674 8452-8463 UBERON:0001986;GO:0017156 denotes endothelium
T675 8463-8473 GO:0017156 denotes -dependent
T676 8474-8486 GO:0042311 denotes vasodilation
T677 8505-8518 CHEBI:26333;CHEBI:26333 denotes prostaglandin
T678 8523-8535 CHEBI:16480;CHEBI:16480 denotes nitric oxide
T679 8575-8578 PR:000001251 denotes AT1
T680 8662-8666 G_3;PG_10;PR:000003622 denotes ACE2
T681 8667-8671 SO:0000704 denotes gene
T682 8698-8701 CHEBI:37886;CHEBI:37886;PR:000036009;GO:0034205 denotes Ang
T683 8702-8704 PR:000036009;GO:0034205 denotes II
T684 8705-8714 GO:0034205 denotes synthesis
T685 8715-8724 GO:0065007 denotes regulated
T686 8725-8729 G_3;PG_10;PR:000003622 denotes ACE2
T687 8743-8747 G_3;PG_10;PR:000003622 denotes ACE2
T688 8816-8824 CHEBI:6541;CHEBI:6541 denotes losartan
T689 8854-8860 UBERON:0001969 denotes plasma
T690 8861-8865 PR:000036013 denotes Ang1
T691 8883-8889 UBERON:0001969 denotes plasma
T692 8890-8896 PR:000036009 denotes Ang II
T693 8931-8935 G_3;PG_10;PR:000003622 denotes ACE2
T694 8969-8977 CHEBI:6541;CHEBI:6541 denotes losartan
T695 9006-9014 CHEBI:6541;CHEBI:6541 denotes losartan
T696 9019-9029 CHEBI:43755;CHEBI:43755 denotes lisinopril
T697 9069-9073 G_3;PG_10;PR:000003622 denotes ACE2
T698 9100-9110 CHEBI:35222;CHEBI:35222 denotes inhibitors
T699 9140-9149 GO:0065007 denotes regulates
T700 9150-9154 G_3;PG_10;PR:000003622 denotes ACE2
T701 9184-9190 PR:000036009 denotes Ang II
T702 9221-9225 PR:000003622;G_3;PG_10 denotes ACE2
T703 9243-9248 PR:000036008 denotes Ang I
T704 9254-9259 PR:000036012 denotes Ang 1
T705 9318-9323 PR:000036008 denotes Ang I
T706 9355-9360 PR:000036013 denotes Ang 1
T707 9389-9399 PR:000001898 denotes neprilysin
T708 9485-9495 CHEBI:35222;CHEBI:35222 denotes inhibitors
T709 9553-9557 G_3;PG_10;PR:000003622 denotes ACE2
T710 9598-9602 G_3;PG_10;PR:000003622 denotes ACE2
T711 9603-9607 PR:000036013 denotes Ang1
T712 9694-9708 GO:0007596 denotes antithrombotic
T713 9737-9741 G_3;PG_10;PR:000003622 denotes ACE2
T714 9742-9746 PR:000036013 denotes Ang1
T715 9749-9752 PR:000001563 denotes Mas
T48220 1670-1681 CL:0000581 denotes severe acu
T422 31-35 CHEBI:24866;CHEBI:24866 denotes lar
T423 66-83 CHEBI:25354;CHEBI:25354 denotes ce of the RAS in
T424 84-104 CHEBI:48561;CHEBI:48561 denotes ardiovascular diseas
T425 133-141 UBERON:0002198 denotes ibitors,
T426 143-149 PR:000036009 denotes RBs, a
T427 202-207 CHEBI:15377;CHEBI:15377 denotes t of
T428 235-242 UBERON:0000479 denotes tral Il
T429 305-313 MOP:0000568 denotes Interac
T430 326-335 GO:0006915 denotes ID-19 Nor
T431 418-421 CHEBI:37886;CHEBI:37886;PR:000036009 denotes me
T432 422-424 PR:000036009 denotes AC
T433 436-440 PR:000001251 denotes uld
T434 442-448 PR:000036009 denotes inhib
T435 474-487 PR:000036013 denotes e pro-inflamm
T436 491-496 PR:000036013 denotes y eff
T437 504-508 PR:000003622;G_3;PG_10 denotes Ang
T438 530-533 PR:000001563 denotes h A
T439 585-589 G_3;PG_10;PR:000003622 denotes he a
T440 590-594 PR:000036013 denotes rena
T441 662-667 PR:000013883 denotes locor
T442 694-698 PR:000001251 denotes wat
T443 703-707 PR:000003622;G_3;PG_10 denotes abso
T444 721-727 PR:000036009 denotes increa
T445 739-743 PR:000001251 denotes ntio
T446 767-771 PR:000003622;G_3;PG_10 denotes nera
T447 829-834 G_3;PG_10;PR:000003622 denotes or pi
T448 874-880 PR:000036009 denotes hormon
T449 895-900 PR:000036013 denotes promo
T450 904-908 G_3;PG_10;PR:000003622 denotes ater
T451 968-980 SP_10 denotes responsible
T452 981-991 SP_10;UBERON:0001004 denotes or hypertr
T453 992-1013 SP_10 denotes phy, fibrosis, oxidat
T454 1015-1023 SP_10 denotes e stress
T455 1031-1039 SP_10 denotes optosis.
T456 1041-1045 G_3;PG_10;PR:000003622 denotes hese
T457 1055-1065 PG_1 denotes re attenua
T458 1089-1094 NCBITaxon:10239;GO:0035376 denotes tor b
T459 1095-1100 GO:0035376 denotes ocker
T460 1110-1122 GO:0044164 denotes which block
T461 1153-1158 NCBITaxon:10239;GO:0006260 denotes can a
T462 1159-1170 GO:0006260 denotes so be conve
T463 1185-1191 PR:000036009 denotes nsin 1
T464 1200-1204 PR:000003622;G_3;PG_10 denotes -7)
T465 1234-1239 NCBITaxon:10239 denotes Mas
T466 1304-1309 PR:000001251 denotes s axi
T467 1334-1339 PR:000001607 denotes atory
T89708 1415-1419 CHEBI:23888;CHEBI:23888 denotes e co
T16250 1435-1445 GO:0065007 denotes nding to A
T24993 1453-1457 G_3;PG_10;PR:000003622 denotes ws d
T40191 1458-1462 PR:000036013 denotes ssoc
T14894 1474-1479 NCBITaxon:10088 denotes E2 an
T95497 1480-1490 UBERON:0001179;CL:0000581 denotes subsequen
T5844 1491-1502 CL:0000581 denotes degradatio
T3127 1525-1536 CHEBI:27584;CHEBI:27584 denotes ation of AC
T32730 1635-1639 G_3;PG_10;PR:000003622 denotes the
T99955 1653-1658 NCBITaxon:10088 denotes ptor
T27470 1659-1669 UBERON:0001179;CL:0000581 denotes or both th
T26688 1696-1708 CHEBI:17154;CHEBI:17154 denotes syndrome cor
T64863 1729-1738 CHEBI:18367;CHEBI:18367 denotes and SARS
T51748 1746-1755 CHEBI:35222;CHEBI:35222 denotes E2 mediat
T79147 1757-1768 CHEBI:27584;CHEBI:27584 denotes S protein
T23025 1805-1809 G_3;PG_10;PR:000003622 denotes nto
T84481 1866-1878 CHEBI:17154;CHEBI:17154 denotes ication. Div
T4704 1984-1994 CHEBI:31547;CHEBI:31547 denotes rse effect
T67581 2002-2007 SP_6;NCBITaxon:9606 denotes by A
T67016 2008-2016 CL:0000576 denotes 1R and i
T80087 2025-2036 CL:0000235 denotes tcomes by M
T18992 2065-2070 UBERON:0000948 denotes Seve
T31322 2135-2148 CHEBI:9241;CHEBI:9241 denotes modulation o
T65607 2229-2239 GO:0010467 denotes dosterone,
T63851 2259-2263 G_3;PG_10;PR:000003622 denotes ican
T37523 2295-2299 G_3;PG_10;PR:000003622 denotes ll a
T52917 2305-2315 GO:0010467 denotes mRNA and s
T20330 2343-2347 NCBITaxon:10088 denotes owev
T67854 2373-2383 CHEBI:31547;CHEBI:31547 denotes crophages
T68420 2385-2392 UBERON:0000948 denotes eated w
T17389 2393-2397 G_3;PG_10;PR:000003622 denotes th n
T21485 2458-2462 G_3;PG_10;PR:000003622 denotes ald
T43223 2475-2486 CL:0000235 denotes d not incre
T52621 2538-2546 MOP:0000568 denotes cts were
T13234 2594-2598 G_3;PG_10;PR:000003622 denotes eoti
T67008 2616-2626 GO:0010467 denotes se (42). T
T6775 2699-2704 PR:000036013 denotes (42)
T76816 2734-2740 PR:000036009 denotes phages
T82259 2751-2762 CHEBI:27584;CHEBI:27584 denotes rom patient
T28961 2773-2777 G_3;PG_10;PR:000003622 denotes t fa
T21763 2802-2814 CHEBI:17154;CHEBI:17154 denotes month of tre
T7075 2835-2845 CHEBI:18367;CHEBI:18367 denotes RA (spiron
T6242 2883-2891 CL:0000359 denotes ion in A
T57466 2892-2904 CL:0000359;UBERON:0004237 denotes E activity a
T21141 2905-2910 CL:0000359 denotes d 53%
T12094 2924-2930 PR:000036009 denotes ACE mR
T22669 2975-2979 PR:000000104 denotes y in
T30163 2988-2991 PR:000009232 denotes y 3
T73442 3028-3051 CHEBI:70982;CHEBI:70982 denotes d by 654% (42). In mice
T49074 3146-3154 MOP:0000568 denotes by incr
T27310 3179-3186 GO:0065007 denotes crophag
T72608 3238-3247 GO:0016020 denotes d oxidati
T87411 3248-3252 G_3;PG_10;PR:000003622 denotes e st
T69430 3253-3263 GO:0010467 denotes ess, decre
T7887 3303-3309 PR:000036009 denotes tivity
T82843 3350-3354 G_3;PG_10;PR:000003622 denotes rote
T64927 3396-3400 G_3;PG_10;PR:000003622 denotes of A
T2864 3493-3497 NCBITaxon:10114 denotes hrou
T75186 3511-3521 CHEBI:48416;CHEBI:48416 denotes ide adenin
T41759 3554-3564 GO:0010467 denotes mediated p
T99248 3568-3572 G_3;PG_10;PR:000003622 denotes ay (
T90139 3592-3596 PR:000036013 denotes smo
T20676 3609-3624 UBERON:0001515 denotes lls, potentiate
T14808 3653-3661 CHEBI:2904;CHEBI:2904 denotes ased pho
T53336 3666-3677 CHEBI:5775;CHEBI:5775 denotes ylation of
T75817 3701-3705 G_3;PG_10;PR:000003622 denotes whi
T33850 3706-3716 GO:0010467 denotes h are also
T31286 3720-3724 PR:000036013 denotes ende
T46627 3747-3753 UBERON:0000055 denotes pecies
T86512 3754-3758 UBERON:0000060 denotes gene
T9294 3817-3831 UBERON:0001515 denotes y associated w
T66808 3832-3837 UBERON:0004363 denotes th re
T37862 3928-3932 NCBITaxon:10114 denotes d to
T72848 3939-3947 CHEBI:2904;CHEBI:2904 denotes e membra
T28474 3951-3962 CHEBI:5775;CHEBI:5775 denotes CE2 express
T95172 3992-3996 G_3;PG_10;PR:000003622 denotes l ef
T54342 3997-4001 PR:000036013 denotes ects
T8468 4004-4014 GO:0010467 denotes Ang II; h
T76399 4038-4054 UBERON:0005396 denotes As on soluble AC
T76616 4070-4077 NCBITaxon:33208 denotes ar. Sim
T23650 4138-4142 G_3;PG_10;PR:000003622 denotes the
T20063 4143-4147 SO:0000704;GO:0010467 denotes ffec
T90002 4152-4159 BV_20 denotes ARB tr
T2173 4160-4170 BV_20;GO:0010467 denotes atment. Sp
T84173 4198-4212 UBERON:0013755 denotes s treated with
T25744 4282-4286 NCBITaxon:10088 denotes incr
T59010 4300-4308 CHEBI:2904;CHEBI:2904 denotes n their
T47013 4312-4323 CHEBI:5775;CHEBI:5775 denotes acic aortas
T34872 4345-4349 NCBITaxon:10114 denotes d wi
T53714 4382-4385 CHEBI:37886;CHEBI:37886;PR:000036009 denotes ite
T14892 4386-4388 PR:000036009 denotes n
T88568 4405-4408 CHEBI:37886;CHEBI:37886;PR:000036009 denotes exp
T25496 4409-4411 PR:000036009 denotes es
T6560 4424-4427 PR:000001251 denotes 7 (
T62928 4452-4455 PR:000001191 denotes wa
T35232 4466-4470 PR:000003622;G_3;PG_10 denotes ns s
T26354 4481-4492 UBERON:0001986 denotes olmesartan
T89670 4493-4504 CHEBI:16480;CHEBI:16480 denotes electively
T84189 4514-4524 GO:0010467 denotes e thoracic
T10845 4547-4551 PR:000001307 denotes atio
T1909 4552-4562 GO:0010467 denotes whereas v
T89580 4596-4600 NCBITaxon:10114 denotes in s
T30307 4614-4625 CHEBI:9434;CHEBI:9434 denotes ypertensive
T38415 4660-4664 G_3;PG_10;PR:000003622 denotes (44
T98868 4678-4689 UBERON:0001986 denotes o change in
T64155 4690-4701 CHEBI:16480;CHEBI:16480 denotes ACE2/Ang1-7
T75423 4711-4721 GO:0010467 denotes n and/or a
T30401 4725-4737 UBERON:0000948 denotes ity in the c
T13751 4738-4745 UBERON:0000055 denotes rotid a
T36514 4750-4765 UBERON:0002349 denotes es of the treat
T22953 4798-4808 GO:0010467 denotes the effect
T33050 4816-4819 PR:000001251 denotes esa
T74336 4845-4856 CHEBI:9434;CHEBI:9434 denotes and protei
T29878 4872-4880 GO:0016020 denotes e the re
T86770 4881-4885 PR:000001307 denotes ult
T46947 4886-4896 GO:0010467 denotes f reduced
T78149 4909-4937 PR:000000046 denotes d pressure was ruled out bec
T7543 4947-4957 GO:0010467 denotes e comparat
T19226 4988-4992 NCBITaxon:10114 denotes ated
T6758 5003-5018 UBERON:0001621 denotes lol or hydralaz
T95747 5028-5044 UBERON:0002084 denotes Sprague-Dawley r
T8675 5111-5119 CHEBI:4670;CHEBI:4670 denotes pregulat
T91170 5162-5168 UBERON:0001969 denotes , ACE2
T42939 5248-5255 UBERON:0000948 denotes 44 expr
T89507 5256-5259 PR:000001251 denotes ssi
T67399 5288-5292 PR:000003622;G_3;PG_10 denotes weve
T50252 5303-5313 UBERON:0002349 denotes ated with
T80802 5374-5381 UBERON:0000948 denotes nd endo
T66318 5433-5436 PR:000001251 denotes dia
T59358 5461-5465 PR:000003622;G_3;PG_10 denotes dium
T3857 5466-5476 GO:0010467 denotes as well a
T15004 5580-5584 G_3;PG_10;PR:000003622 denotes CD4
T55429 5585-5595 GO:0010467 denotes expressio
T56789 5603-5613 UBERON:0002349 denotes duced tran
T22016 5669-5673 G_3;PG_10;PR:000003622 denotes es i
T73746 5679-5686 GO:0009986 denotes otensiv
T3793 5687-5697 GO:0010467 denotes rats with
T94556 5702-5708 UBERON:0001969 denotes -coron
T7532 5709-5713 G_3;PG_10;PR:000003622 denotes ry a
T59750 5744-5748 NCBITaxon:10114 denotes rem
T68812 5754-5758 UBERON:0001652 denotes g an
T80708 5759-5774 UBERON:0001626 denotes dysfunction ex
T19064 5788-5798 UBERON:0002349 denotes l resoluti
T68086 5811-5817 UBERON:0001969 denotes losart
T9555 5818-5824 PR:000036009 denotes n and
T46842 5859-5865 UBERON:0001969 denotes ng pla
T63923 5866-5870 PR:000003622;G_3;PG_10 denotes ma c
T57073 5905-5912 UBERON:0000948 denotes 46). Th
T11029 5913-5917 PR:000003622;G_3;PG_10 denotes s wa
T22615 5922-5925 PR:000001251 denotes oci
T54648 6021-6031 UBERON:0002349 denotes on, which
T39259 6053-6061 CHEBI:8774;CHEBI:8774 denotes effects
T49629 6098-6104 UBERON:0001969 denotes ccompa
T84997 6105-6108 CHEBI:29101;CHEBI:29101;PR:000036008 denotes ied
T62274 6109-6110 PR:000036008;CHEBI:16382;CHEBI:16382 denotes b
T49616 6115-6121 PR:000036009 denotes ect bl
T93686 6141-6147 UBERON:0001969 denotes ors an
T73758 6156-6160 PR:000003622;G_3;PG_10 denotes ed A
T15813 6233-6237 PR:000003622;G_3;PG_10 denotes sult
T48553 6241-6244 PR:000001251 denotes rta
T52193 6254-6264 GO:0010467 denotes RB use and
T47893 6317-6327 UBERON:0002349 denotes of the co
T5376 6391-6396 NCBITaxon:39107 denotes sion
T50240 6418-6422 G_3;PG_10;PR:000003622 denotes . In
T48024 6480-6490 UBERON:0002349 denotes n and myoc
T2031 6497-6507 UBERON:0002349 denotes infarction
T75536 6535-6543 CHEBI:8774;CHEBI:8774 denotes ere not
T21825 6556-6566 GO:0010467 denotes plasma AC
T49779 6576-6580 G_3;PG_10;PR:000003622 denotes vate
T30668 6679-6684 NCBITaxon:39107 denotes gulat
T69554 6724-6734 CHEBI:48416;CHEBI:48416 denotes rdium (47)
T74716 6738-6749 CHEBI:9434;CHEBI:9434 denotes eatment wit
T88764 6765-6772 UBERON:0000948 denotes alsarta
T80829 6773-6777 G_3;PG_10;PR:000003622 denotes res
T65771 6787-6794 BV_20 denotes ncrease
T58470 6795-6805 BV_20;GO:0010467 denotes plasma An
T72678 6823-6829 UBERON:0001969 denotes suppr
T79500 6830-6834 PR:000036013 denotes ssio
T87382 6879-6886 UBERON:0000948 denotes either
T91462 6980-6990 CHEBI:35222;CHEBI:35222 denotes mained at
T59581 7021-7025 G_3;PG_10;PR:000003622 denotes dial
T32923 7026-7036 GO:0010467 denotes infarction
T89116 7069-7072 CHEBI:37886;CHEBI:37886;PR:000036009 denotes s s
T52084 7073-7075 PR:000036009 denotes ud
T59745 7126-7132 PR:000036009 denotes gulati
T42872 7150-7154 PR:000003622;G_3;PG_10 denotes infa
T18348 7173-7177 PR:000036013 denotes iabl
T25440 7212-7216 G_3;PG_10;PR:000003622 denotes ctio
T42655 7217-7221 PR:000036013 denotes . Tr
T1503 7252-7261 GO:0065007 denotes CE expres
T18131 7269-7272 PR:000001251 denotes ere
T33157 7333-7340 UBERON:0000948 denotes rol sub
T63784 7363-7369 PR:000036009 denotes dy in
T32447 7400-7410 CHEBI:35222;CHEBI:35222 denotes ted that t
T28230 7437-7441 G_3;PG_10;PR:000003622 denotes tel
T56486 7466-7476 CHEBI:35222;CHEBI:35222 denotes ardiac ACE
T60150 7498-7502 PR:000036013 denotes ress
T27622 7585-7595 CHEBI:35222;CHEBI:35222 denotes c function
T45254 7622-7625 PR:000036008 denotes spo
T68302 7626-7627 PR:000036008;CHEBI:16382;CHEBI:16382 denotes i
T53701 7631-7634 CHEBI:37886;CHEBI:37886;PR:000036009 denotes (4
T10363 7635-7637 PR:000036009 denotes ).
T56333 7654-7664 MOP:0000619 denotes s suggeste
T27917 7668-7678 CHEBI:3165;CHEBI:3165 denotes at both AC
T15920 7732-7742 CHEBI:3165;CHEBI:3165 denotes sion (49).
T33386 7753-7764 UBERON:0001986;GO:0017156 denotes ited bindin
T67450 7764-7774 GO:0017156 denotes g of Ang I
T25824 7775-7787 GO:0042311 denotes to the AT1
T87208 7806-7819 CHEBI:26333;CHEBI:26333 denotes mitted circul
T9658 7824-7835 CHEBI:16480;CHEBI:16480 denotes Ang II to
T36835 7875-7878 PR:000001251 denotes 1-7
T72048 7963-7967 G_3;PG_10;PR:000003622 denotes y th
T5759 7968-7972 SO:0000704 denotes AT1
T63904 7999-8002 CHEBI:37886;CHEBI:37886;PR:000036009;GO:0034205 denotes ant
T97196 8003-8005 PR:000036009;GO:0034205 denotes in
T84140 8006-8015 GO:0034205 denotes mediating
T65944 8016-8025 GO:0065007 denotes the vascu
T2616 8026-8030 G_3;PG_10;PR:000003622 denotes ar a
T8775 8044-8048 G_3;PG_10;PR:000003622 denotes odel
T7666 8117-8125 CHEBI:6541;CHEBI:6541 denotes complex
T40696 8155-8161 UBERON:0001969 denotes ed by
T51121 8162-8166 PR:000036013 denotes CE i
T58974 8184-8190 UBERON:0001969 denotes incre
T80784 8191-8197 PR:000036009 denotes se in
T33334 8232-8236 G_3;PG_10;PR:000003622 denotes cts
T83597 8270-8278 CHEBI:6541;CHEBI:6541 denotes nsinases
T62347 8307-8315 CHEBI:6541;CHEBI:6541 denotes conversi
T16234 8320-8330 CHEBI:43755;CHEBI:43755 denotes Ang I to
T90761 8370-8374 G_3;PG_10;PR:000003622 denotes dyki
T25248 8401-8411 CHEBI:35222;CHEBI:35222 denotes s the vaso
T50049 8441-8450 GO:0065007 denotes , improve
T45483 8451-8455 G_3;PG_10;PR:000003622 denotes end
T32689 8485-8491 PR:000036009 denotes n thro
T27991 8522-8526 PR:000003622;G_3;PG_10 denotes nit
T22569 8545-8550 PR:000036008 denotes n, an
T41693 8556-8561 PR:000036012 denotes regu
T9119 8620-8625 PR:000036008 denotes dated
T90264 8657-8662 PR:000036013 denotes the
T46244 8689-8699 PR:000001898 denotes ition of A
T39670 8785-8795 CHEBI:35222;CHEBI:35222 denotes n alone or
T35970 8853-8857 G_3;PG_10;PR:000003622 denotes pla
T45388 8898-8902 G_3;PG_10;PR:000003622 denotes 53).
T37721 8903-8907 PR:000036013 denotes Comp
T77914 8993-9007 GO:0007596 denotes mbination of l
T92396 9036-9040 G_3;PG_10;PR:000003622 denotes ed i
T36791 9041-9045 PR:000036013 denotes sup
T91226 9048-9051 PR:000001563 denotes sse
T41455 9116-9120 G_3;PG_10;PR:000003622 denotes ove
T47287 9125-9129 PR:000036013 denotes a s
T94041 9149-9153 G_3;PG_10;PR:000003622 denotes ACE
T46256 9154-9163 GO:0065007 denotes transcri
T27522 9190-9196 PR:000036009 denotes is th
T18328 9197-9200 PR:000001251 denotes pr
T97445 9242-9246 G_3;PG_10;PR:000003622 denotes Ang
T95349 9247-9251 PR:000036013 denotes I in
T57032 9370-9382 UBERON:0001004 denotes c metallopep
T84387 9419-9437 UBERON:0002012 denotes less favorable ki
T17302 9460-9465 NCBITaxon:39107 denotes s, it
T83070 9494-9503 GO:0065007 denotes s disrupt
T26990 9574-9580 NCBITaxon:9606 denotes vored
T44915 9653-9658 SP_6;NCBITaxon:9606;PG_10 denotes ted a
T17920 9659-9690 PG_10;PR:000003622 denotes ti-inflammatory, antifibrotic,

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
428 0-4 Gene denotes ACE2 Gene:59272
429 20-42 Disease denotes Cardiovascular Disease MESH:D002318
431 323-331 Disease denotes COVID-19 MESH:C000657245
470 342-355 Gene denotes angiotensin I Gene:183
471 357-362 Gene denotes Ang I Gene:183
472 380-386 Gene denotes Ang II Gene:183
473 391-420 Gene denotes angiotensin-converting enzyme Gene:1636
474 422-425 Gene denotes ACE Gene:1636
475 456-459 Gene denotes ACE Gene:1636
476 504-510 Gene denotes Ang II Gene:183
477 532-536 Gene denotes AT1R Gene:185
478 765-791 Gene denotes mineralocorticoid receptor Gene:4306
479 843-849 Gene denotes Ang II Gene:183
480 1122-1128 Gene denotes Ang II Gene:183
481 1140-1144 Gene denotes AT1R Gene:185
482 1146-1152 Gene denotes Ang II Gene:183
483 1195-1202 Gene denotes Ang 1-7 Gene:284
484 1208-1212 Gene denotes ACE2 Gene:59272
485 1290-1294 Gene denotes ACE2 Gene:59272
486 1295-1301 Gene denotes Ang1-7 Gene:284
487 1399-1403 Gene denotes AT1R Gene:185
488 1408-1412 Gene denotes ACE2 Gene:59272
489 1426-1432 Gene denotes Ang II Gene:183
490 1444-1448 Gene denotes AT1R Gene:185
491 1472-1476 Gene denotes ACE2 Gene:59272
492 1534-1538 Gene denotes ACE2 Gene:59272
493 1599-1606 Gene denotes Ang 1-7 Gene:284
494 1608-1612 Gene denotes ACE2 Gene:59272
495 1744-1748 Gene denotes ACE2 Gene:59272
496 1903-1907 Gene denotes ACE2 Gene:59272
497 2006-2010 Gene denotes AT1R Gene:185
498 1578-1584 Gene denotes Ang II Gene:183
499 1888-1891 Gene denotes Ang Gene:283
500 1671-1716 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
501 1718-1729 Species denotes SARS-CoV) 2 Tax:2697049
502 1734-1742 Species denotes SARS-CoV Tax:694009
503 695-700 Chemical denotes water MESH:D014867
504 903-908 Chemical denotes water MESH:D014867
505 984-995 Disease denotes hypertrophy MESH:D006984
506 997-1005 Disease denotes fibrosis MESH:D005355
507 1842-1851 Disease denotes infection MESH:D007239
511 126-129 Gene denotes ACE Gene:1636
512 83-105 Disease denotes cardiovascular disease MESH:D002318
513 207-230 Disease denotes cardiovascular diseases MESH:D002318
552 2154-2158 Gene denotes ACE2 Gene:59272
553 2159-2165 Gene denotes Ang1-7 Gene:284
554 2277-2280 Gene denotes ACE Gene:11421
555 2301-2304 Gene denotes ACE Gene:11421
556 2336-2340 Gene denotes ACE2 Gene:70008
557 2490-2493 Gene denotes ACE Gene:11421
558 2506-2510 Gene denotes ACE2 Gene:70008
559 2924-2927 Gene denotes ACE Gene:1636
560 2963-2967 Gene denotes ACE2 Gene:59272
561 2999-3003 Gene denotes ACE2 Gene:59272
562 3097-3101 Gene denotes ACE2 Gene:70008
563 3160-3164 Gene denotes ACE2 Gene:70008
564 3268-3271 Gene denotes ACE Gene:11421
565 3296-3300 Gene denotes ACE2 Gene:70008
566 3399-3406 Gene denotes Ang 1-7 Gene:284
567 3434-3440 Gene denotes Ang II Gene:183
568 3473-3477 Gene denotes ACE2 Gene:70008
569 3626-3632 Gene denotes Ang II Gene:183
570 3677-3683 Gene denotes ERK1/2 Gene:5595
571 3950-3954 Gene denotes ACE2 Gene:70008
572 4005-4011 Gene denotes Ang II Gene:183
573 4052-4056 Gene denotes ACE2 Gene:70008
574 2890-2893 Gene denotes ACE Gene:1636
575 2176-2181 Species denotes Mouse Tax:10090
576 2354-2359 Species denotes mouse Tax:10090
577 2706-2711 Species denotes Human Tax:9606
578 2755-2763 Species denotes patients Tax:9606
579 3047-3051 Species denotes mice Tax:10090
580 2227-2238 Chemical denotes aldosterone MESH:D000450
581 2396-2429 Chemical denotes nicotinamide adenine dinucleotide MESH:D009243
582 2459-2470 Chemical denotes aldosterone MESH:D000450
583 2688-2698 Chemical denotes eplerenone MESH:D000077545
584 2839-2853 Chemical denotes spironolactone MESH:D013148
585 3077-3087 Chemical denotes eplerenone MESH:D000077545
586 3451-3462 Chemical denotes aldosterone MESH:D000450
587 3502-3535 Chemical denotes nicotinamide adenine dinucleotide MESH:D009243
588 3739-3745 Chemical denotes oxygen MESH:D010100
589 2769-2782 Disease denotes heart failure MESH:D006333
613 4098-4102 Gene denotes ACE2 Gene:59272
614 4268-4272 Gene denotes ACE2 Gene:302668
615 4292-4298 Gene denotes Ang1-7 Gene:305843
616 4400-4404 Gene denotes ACE2 Gene:302668
617 4419-4425 Gene denotes Ang1-7 Gene:305843
618 4690-4694 Gene denotes ACE2 Gene:302668
619 4695-4701 Gene denotes Ang1-7 Gene:305843
620 4836-4840 Gene denotes ACE2 Gene:70008
621 4195-4199 Species denotes rats Tax:10116
622 4626-4630 Species denotes rats Tax:10116
623 4980-4984 Species denotes mice Tax:10090
624 4213-4223 Chemical denotes olmesartan MESH:C437965
625 4352-4360 Chemical denotes atenolol MESH:D001262
626 4365-4376 Chemical denotes hydralazine MESH:D006830
627 4481-4491 Chemical denotes olmesartan MESH:C437965
628 4637-4645 Chemical denotes atenolol MESH:D001262
629 4649-4660 Chemical denotes hydralazine MESH:D006830
630 4813-4823 Chemical denotes olmesartan MESH:C437965
631 4998-5006 Chemical denotes atenolol MESH:D001262
632 5010-5021 Chemical denotes hydralazine MESH:D006830
633 4182-4194 Disease denotes hypertensive MESH:D006973
634 4561-4581 Disease denotes vascular hypertrophy MESH:D006984
635 4613-4625 Disease denotes hypertensive MESH:D006973
695 5080-5086 Gene denotes Ang II Gene:183
696 5164-5168 Gene denotes ACE2 Gene:59272
697 5179-5212 Gene denotes endothelial nitric oxide synthase Gene:4846
698 5359-5363 Gene denotes ACE2 Gene:302668
699 5377-5410 Gene denotes endothelial nitric oxide synthase Gene:4846
700 5609-5637 Gene denotes transforming growth factor−β Gene:7124
701 5987-5991 Gene denotes ACE2 Gene:302668
702 6159-6163 Gene denotes ACE2 Gene:302668
703 6278-6282 Gene denotes ACE2 Gene:302668
704 6367-6371 Gene denotes ACE2 Gene:302668
705 6407-6411 Gene denotes ACE2 Gene:302668
706 6516-6522 Gene denotes Ang II Gene:24179
707 6527-6533 Gene denotes Ang1-7 Gene:305843
708 6564-6568 Gene denotes ACE2 Gene:302668
709 6611-6615 Gene denotes ACE2 Gene:302668
710 6846-6849 Gene denotes ACE Gene:24310
711 6854-6858 Gene denotes ACE2 Gene:302668
712 6931-6935 Gene denotes ACE2 Gene:302668
713 7109-7112 Gene denotes ACE Gene:11421
714 7117-7121 Gene denotes ACE2 Gene:70008
715 7251-7254 Gene denotes ACE Gene:11421
716 7275-7279 Gene denotes ACE2 Gene:70008
717 7473-7477 Gene denotes ACE2 Gene:70008
718 7530-7536 Gene denotes Ang1-7 Gene:11727
719 7537-7543 Gene denotes Ang II Gene:11606
720 7676-7679 Gene denotes ACE Gene:11421
721 7721-7725 Gene denotes ACE2 Gene:70008
722 7769-7775 Gene denotes Ang II Gene:11606
723 7825-7831 Gene denotes Ang II Gene:11606
724 7849-7853 Gene denotes ACE2 Gene:70008
725 7872-7878 Gene denotes Ang1-7 Gene:11727
726 7911-7915 Gene denotes ACE2 Gene:70008
727 7916-7922 Gene denotes Ang1-7 Gene:11727
728 8063-8069 Gene denotes Ang II Gene:11606
729 6803-6806 Gene denotes Ang Gene:283
730 5103-5106 Gene denotes Ang Gene:283
731 5028-5047 Species denotes Sprague-Dawley rats Tax:10116
732 5295-5299 Species denotes rats Tax:10116
733 5688-5692 Species denotes rats Tax:10116
734 6427-6446 Species denotes Sprague-Dawley rats Tax:10116
735 7089-7095 Species denotes murine Tax:10090
736 7378-7384 Species denotes murine Tax:10090
737 6813-6816 Gene denotes Ang Gene:283
738 5313-5324 Chemical denotes telmisartan MESH:D000077333
739 5545-5556 Chemical denotes telmisartan MESH:D000077333
740 5811-5819 Chemical denotes losartan MESH:D019808
741 5824-5834 Chemical denotes olmesartan MESH:C437965
742 6751-6759 Chemical denotes ramipril MESH:D017257
743 6764-6773 Chemical denotes valsartan MESH:D000068756
744 7234-7242 Chemical denotes ramipril MESH:D017257
745 7424-7434 Chemical denotes olmesartan MESH:C437965
746 7438-7449 Chemical denotes telmisartan MESH:D000077333
747 5733-5771 Disease denotes ventricular remodeling and dysfunction MESH:D020257
748 6002-6023 Disease denotes myocardial infarction MESH:D009203
749 6486-6507 Disease denotes myocardial infarction MESH:D009203
750 6645-6652 Disease denotes infarct MESH:D007238
751 7015-7036 Disease denotes myocardial infarction MESH:D009203
752 7150-7163 Disease denotes infarct zones MESH:D007238
753 7196-7217 Disease denotes myocardial infarction MESH:D009203
796 8095-8098 Gene denotes ACE Gene:1636
797 8136-8140 Gene denotes ACE2 Gene:59272
798 8161-8164 Gene denotes ACE Gene:1636
799 8197-8203 Gene denotes Ang1-7 Gene:284
800 8280-8283 Gene denotes ACE Gene:1636
801 8367-8377 Gene denotes bradykinin Gene:3827
802 8379-8382 Gene denotes ACE Gene:1636
803 8431-8441 Gene denotes bradykinin Gene:3827
804 8640-8643 Gene denotes ACE Gene:1636
805 8662-8666 Gene denotes ACE2 Gene:59272
806 8698-8704 Gene denotes Ang II Gene:183
807 8725-8729 Gene denotes ACE2 Gene:59272
808 8743-8747 Gene denotes ACE2 Gene:59272
809 8772-8775 Gene denotes ACE Gene:1636
810 8861-8867 Gene denotes Ang1-7 Gene:284
811 8890-8896 Gene denotes Ang II Gene:183
812 8931-8935 Gene denotes ACE2 Gene:59272
813 9069-9073 Gene denotes ACE2 Gene:59272
814 9096-9099 Gene denotes ACE Gene:1636
815 9150-9154 Gene denotes ACE2 Gene:59272
816 9184-9190 Gene denotes Ang II Gene:183
817 9221-9225 Gene denotes ACE2 Gene:59272
818 9254-9261 Gene denotes Ang 1-9 Gene:284
819 9301-9308 Gene denotes Ang 1-7 Gene:284
820 9313-9316 Gene denotes ACE Gene:1636
821 9318-9323 Gene denotes Ang I Gene:183
822 9355-9362 Gene denotes Ang 1-7 Gene:284
823 9389-9399 Gene denotes neprilysin Gene:4311
824 9481-9484 Gene denotes ACE Gene:1636
825 9545-9548 Gene denotes ACE Gene:1636
826 9553-9557 Gene denotes ACE2 Gene:59272
827 9598-9602 Gene denotes ACE2 Gene:59272
828 9603-9609 Gene denotes Ang1-7 Gene:284
829 8330-8336 Gene denotes Ang II Gene:183
830 9243-9248 Gene denotes Ang I Gene:183
831 8321-8326 Gene denotes Ang I Gene:183
832 8505-8518 Chemical denotes prostaglandin MESH:D011453
833 8523-8535 Chemical denotes nitric oxide MESH:D009569
834 8816-8824 Chemical denotes losartan MESH:D019808
835 8969-8977 Chemical denotes losartan MESH:D019808
836 9006-9014 Chemical denotes losartan MESH:D019808
837 9019-9029 Chemical denotes lisinopril MESH:D017706
840 9737-9741 Gene denotes ACE2 Gene:59272
841 9742-9748 Gene denotes Ang1-7 Gene:284

2_test

Id Subject Object Predicate Lexical cue
32305401-16179584-55252946 2620-2622 16179584 denotes 42
32305401-16179584-55252947 2701-2703 16179584 denotes 42
32305401-16179584-55252948 3039-3041 16179584 denotes 42
32305401-16179584-55252949 3190-3192 16179584 denotes 42
32305401-16179584-55252950 3572-3574 16179584 denotes 42
32305401-15159288-55252951 3766-3768 15159288 denotes 43
32305401-15833808-55252952 4427-4429 15833808 denotes 44
32305401-15833808-55252953 4662-4664 15833808 denotes 44
32305401-15833808-55252954 5023-5025 15833808 denotes 44
32305401-27085217-55252955 5281-5283 27085217 denotes 45
32305401-27085217-55252956 5659-5661 27085217 denotes 45
32305401-15007027-55252957 5905-5907 15007027 denotes 46
32305401-15007027-55252958 6192-6194 15007027 denotes 46
32305401-22715807-55252959 6661-6663 22715807 denotes 47
32305401-22715807-55252960 6731-6733 22715807 denotes 47
32305401-22715807-55252961 7046-7048 22715807 denotes 47
32305401-28656296-55252962 7633-7635 28656296 denotes 49
32305401-28656296-55252963 7738-7740 28656296 denotes 49
32305401-2849100-55252964 8177-8179 2849100 denotes 19
32305401-10892668-55252965 8589-8591 10892668 denotes 50
32305401-8793704-55252966 8593-8595 8793704 denotes 51
32305401-9461243-55252967 8758-8760 9461243 denotes 53
32305401-9461243-55252968 8898-8900 9461243 denotes 53
32305401-9461243-55252969 9170-9172 9461243 denotes 53
32305401-15283675-55252970 9401-9403 15283675 denotes 17