PMC:7161517 / 86-490 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":98,"end":102},"obj":"Body_part"},{"id":"T2","span":{"begin":296,"end":300},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma12520"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T2","span":{"begin":32,"end":79},"obj":"Disease"},{"id":"T3","span":{"begin":81,"end":89},"obj":"Disease"},{"id":"T4","span":{"begin":103,"end":112},"obj":"Disease"},{"id":"T5","span":{"begin":214,"end":222},"obj":"Disease"}],"attributes":[{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":98,"end":102},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T2","span":{"begin":332,"end":340},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":139,"end":150},"obj":"Chemical"},{"id":"T3","span":{"begin":267,"end":278},"obj":"Chemical"},{"id":"T4","span":{"begin":390,"end":404},"obj":"Chemical"},{"id":"T7","span":{"begin":390,"end":401},"obj":"Chemical"},{"id":"T8","span":{"begin":402,"end":404},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_2719"},{"id":"A5","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_48432"},{"id":"A6","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_58506"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}

{"project":"LitCovid-sentences","denotations":[{"id":"T3","span":{"begin":23,"end":31},"obj":"Sentence"},{"id":"T4","span":{"begin":32,"end":178},"obj":"Sentence"},{"id":"T5","span":{"begin":179,"end":381},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T3","span":{"begin":32,"end":44},"obj":"SP_7"},{"id":"T4","span":{"begin":45,"end":56},"obj":"SP_7;UBERON:0001004"},{"id":"T5","span":{"begin":56,"end":79},"obj":"SP_7"},{"id":"T6","span":{"begin":81,"end":91},"obj":"SP_7"},{"id":"T7","span":{"begin":139,"end":170},"obj":"PG_10;PR:000003622"},{"id":"T8","span":{"begin":172,"end":176},"obj":"G_3;PG_10;PR:000003622"},{"id":"T9","span":{"begin":188,"end":201},"obj":"GO:0065007"},{"id":"T10","span":{"begin":214,"end":222},"obj":"SP_10"},{"id":"T11","span":{"begin":262,"end":266},"obj":"G_3;PG_10;PR:000003622"},{"id":"T12","span":{"begin":267,"end":280},"obj":"PR:000036013"},{"id":"T13","span":{"begin":284,"end":288},"obj":"PR:000036013"},{"id":"T14","span":{"begin":327,"end":331},"obj":"G_3;PG_10;PR:000003622"},{"id":"T15","span":{"begin":390,"end":404},"obj":"DG_37;PR:000001118"},{"id":"T60295","span":{"begin":32,"end":44},"obj":"SP_7"},{"id":"T90939","span":{"begin":45,"end":56},"obj":"SP_7;UBERON:0001004"},{"id":"T19070","span":{"begin":56,"end":79},"obj":"SP_7"},{"id":"T26357","span":{"begin":81,"end":91},"obj":"SP_7"},{"id":"T3432","span":{"begin":139,"end":170},"obj":"PG_10;PR:000003622"},{"id":"T99057","span":{"begin":172,"end":176},"obj":"G_3;PG_10;PR:000003622"},{"id":"T53282","span":{"begin":188,"end":201},"obj":"GO:0065007"},{"id":"T31949","span":{"begin":214,"end":222},"obj":"SP_10"},{"id":"T17436","span":{"begin":262,"end":266},"obj":"G_3;PG_10;PR:000003622"},{"id":"T37458","span":{"begin":267,"end":280},"obj":"PR:000036013"},{"id":"T46294","span":{"begin":284,"end":288},"obj":"PR:000036013"},{"id":"T60166","span":{"begin":327,"end":331},"obj":"G_3;PG_10;PR:000003622"},{"id":"T39187","span":{"begin":390,"end":404},"obj":"DG_37;PR:000001118"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}

{"project":"LitCovid-PubTator","denotations":[{"id":"21","span":{"begin":139,"end":170},"obj":"Gene"},{"id":"22","span":{"begin":172,"end":176},"obj":"Gene"},{"id":"23","span":{"begin":262,"end":282},"obj":"Gene"},{"id":"24","span":{"begin":284,"end":290},"obj":"Gene"},{"id":"25","span":{"begin":327,"end":331},"obj":"Gene"},{"id":"31","span":{"begin":32,"end":79},"obj":"Species"},{"id":"32","span":{"begin":81,"end":91},"obj":"Species"},{"id":"33","span":{"begin":214,"end":222},"obj":"Species"},{"id":"36","span":{"begin":103,"end":112},"obj":"Disease"}],"attributes":[{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"Gene:59272"},{"id":"A22","pred":"tao:has_database_id","subj":"22","obj":"Gene:59272"},{"id":"A23","pred":"tao:has_database_id","subj":"23","obj":"Gene:59272"},{"id":"A24","pred":"tao:has_database_id","subj":"24","obj":"Gene:284"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"Gene:59272"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"Tax:2697049"},{"id":"A32","pred":"tao:has_database_id","subj":"32","obj":"Tax:2697049"},{"id":"A33","pred":"tao:has_database_id","subj":"33","obj":"Tax:694009"},{"id":"A36","pred":"tao:has_database_id","subj":"36","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"iew Topic of the Week\n\nAbstract\nSevere acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation observed in SARS-CoV was previously postulated to be due to ACE2/angiotensin 1-7 (Ang1-7)/Mas axis downregulation; increased ACE2 activity was shown to mediate disease protection. Because angiotensin II"}