PMC:7161517 / 773-1130 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":83,"end":87},"obj":"Body_part"},{"id":"T4","span":{"begin":128,"end":132},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T2","span":{"begin":128,"end":132},"obj":"Body_part"},{"id":"T3","span":{"begin":239,"end":263},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0018229"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T8","span":{"begin":157,"end":165},"obj":"Disease"},{"id":"T9","span":{"begin":166,"end":176},"obj":"Disease"},{"id":"T10","span":{"begin":278,"end":286},"obj":"Disease"}],"attributes":[{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T4","span":{"begin":128,"end":132},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T5","span":{"begin":128,"end":132},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T6","span":{"begin":181,"end":184},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T13","span":{"begin":245,"end":256},"obj":"Chemical"},{"id":"T14","span":{"begin":264,"end":274},"obj":"Chemical"}],"attributes":[{"id":"A13","pred":"chebi_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-sentences","denotations":[{"id":"T7","span":{"begin":0,"end":357},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T25","span":{"begin":67,"end":71},"obj":"G_3;PG_10;PR:000003622"},{"id":"T26","span":{"begin":72,"end":76},"obj":"PR:000036013"},{"id":"T27","span":{"begin":128,"end":132},"obj":"UBERON:0002048"},{"id":"T28","span":{"begin":157,"end":165},"obj":"SP_10"},{"id":"T29","span":{"begin":239,"end":244},"obj":"PR:000013883"},{"id":"T30","span":{"begin":264,"end":274},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T31","span":{"begin":278,"end":288},"obj":"SP_7"},{"id":"T69502","span":{"begin":67,"end":71},"obj":"G_3;PG_10;PR:000003622"},{"id":"T7389","span":{"begin":72,"end":76},"obj":"PR:000036013"},{"id":"T3955","span":{"begin":128,"end":132},"obj":"UBERON:0002048"},{"id":"T22854","span":{"begin":157,"end":165},"obj":"SP_10"},{"id":"T79821","span":{"begin":239,"end":244},"obj":"PR:000013883"},{"id":"T54661","span":{"begin":264,"end":274},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T15931","span":{"begin":278,"end":288},"obj":"SP_7"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}

{"project":"LitCovid-PubTator","denotations":[{"id":"29","span":{"begin":67,"end":71},"obj":"Gene"},{"id":"30","span":{"begin":72,"end":78},"obj":"Gene"},{"id":"35","span":{"begin":278,"end":288},"obj":"Species"},{"id":"39","span":{"begin":157,"end":176},"obj":"Disease"}],"attributes":[{"id":"A29","pred":"tao:has_database_id","subj":"29","obj":"Gene:59272"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"Gene:284"},{"id":"A35","pred":"tao:has_database_id","subj":"35","obj":"Tax:2697049"},{"id":"A39","pred":"tao:has_database_id","subj":"39","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Based on the anti-inflammatory benefits of the upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits of treatment with renin-angiotensin system inhibitors in SARS-CoV-2 may outweigh the risks and at the very least should not be withheld."}