PMC:7161517 / 31050-31943
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T185 | 0-18 | Body_part | denotes | Lipopolysaccharide | http://purl.org/sig/ont/fma/fma82785 |
T186 | 33-37 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T187 | 98-102 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T188 | 178-183 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T189 | 241-245 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T190 | 259-263 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T191 | 341-359 | Body_part | denotes | lipopolysaccharide | http://purl.org/sig/ont/fma/fma82785 |
T192 | 430-437 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T193 | 459-463 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T194 | 539-543 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T77 | 33-37 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T78 | 98-102 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T79 | 241-245 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T80 | 259-263 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T81 | 459-463 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T82 | 501-504 | Body_part | denotes | RAS | http://purl.obolibrary.org/obo/UBERON_0018229 |
T83 | 539-543 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T84 | 648-651 | Body_part | denotes | RAS | http://purl.obolibrary.org/obo/UBERON_0018229 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T166 | 27-44 | Disease | denotes | acute lung injury | http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796 |
T168 | 38-44 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T169 | 120-126 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T170 | 264-270 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T171 | 378-384 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T172 | 419-427 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T173 | 515-523 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T174 | 590-593 | Disease | denotes | AT1 | http://purl.obolibrary.org/obo/MONDO_0008840 |
T175 | 680-688 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T294 | 33-37 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T295 | 33-37 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T296 | 45-50 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T297 | 98-102 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T298 | 98-102 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T299 | 178-183 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T300 | 241-245 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T301 | 241-245 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T302 | 259-263 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T303 | 259-263 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T304 | 459-463 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T305 | 459-463 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T306 | 539-543 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T307 | 539-543 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T326 | 0-18 | Chemical | denotes | Lipopolysaccharide | http://purl.obolibrary.org/obo/CHEBI_16412|http://purl.obolibrary.org/obo/CHEBI_89981 |
T328 | 301-315 | Chemical | denotes | ACE inhibitors | http://purl.obolibrary.org/obo/CHEBI_35457 |
T329 | 305-315 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T330 | 341-359 | Chemical | denotes | lipopolysaccharide | http://purl.obolibrary.org/obo/CHEBI_16412 |
T331 | 430-437 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T332 | 501-504 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
T333 | 648-651 | Chemical | denotes | RAS | http://purl.obolibrary.org/obo/CHEBI_63620 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T189 | 0-271 | Sentence | denotes | Lipopolysaccharide-induced acute lung injury mouse models exhibited decreased expression of ACE2, lung and inflammatory injury; however, this was ameliorated by the injection of cells transfected with ACE2 and resulted in the improvement of lung function and lung injury. |
T190 | 272-390 | Sentence | denotes | Treatment of these mice with ACE inhibitors and ARBs also alleviated lipopolysaccharide-induced pneumonic injury (67). |
T191 | 391-505 | Sentence | denotes | Previous studies showed the SARS-CoV S protein can exaggerate acute lung failure through dysregulation of the RAS. |
T192 | 506-608 | Sentence | denotes | However, SARS-CoV Spike–mediated lung failure could be rescued by inhibition of the AT1 receptor (67). |
T193 | 609-893 | Sentence | denotes | Again, adequate data on the effects of RAS inhibition in patients with COVID-19 is not available, and ongoing clinical and/or observations studies are being conducted (see previous mentions of NCT04318301, NCT04318418, NCT04312009, NCT04311177, NCT04287686, NCT04330300, NCT04329195). |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T48 | 27-44 | Phenotype | denotes | acute lung injury | http://www.orpha.net/ORDO/Orphanet_178320 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1012 | 0-18 | CHEBI:16412;CHEBI:16412 | denotes | Lipopolysaccharide |
T1013 | 33-37 | UBERON:0002048 | denotes | lung |
T1014 | 45-50 | NCBITaxon:10088 | denotes | mouse |
T1015 | 78-88 | GO:0010467 | denotes | expression |
T1016 | 92-96 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T1017 | 98-102 | UBERON:0002048 | denotes | lung |
T1018 | 184-195 | GO:0009294 | denotes | transfected |
T1019 | 201-205 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T1020 | 241-245 | UBERON:0002048 | denotes | lung |
T1021 | 259-263 | UBERON:0002048 | denotes | lung |
T1022 | 291-295 | NCBITaxon:10088 | denotes | mice |
T1023 | 305-315 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
T1024 | 341-359 | CHEBI:16412;CHEBI:16412 | denotes | lipopolysaccharide |
T1025 | 368-377 | UBERON:0006562 | denotes | pneumonic |
T1026 | 419-427 | SP_10 | denotes | SARS-CoV |
T1027 | 428-437 | PG_1 | denotes | S protein |
T1028 | 459-463 | UBERON:0002048 | denotes | lung |
T1029 | 480-493 | GO:0065007 | denotes | dysregulation |
T1030 | 515-523 | SP_10 | denotes | SARS-CoV |
T1031 | 539-543 | UBERON:0002048 | denotes | lung |
T1032 | 590-593 | PR:000001251 | denotes | AT1 |
T1033 | 680-688 | SP_7 | denotes | COVID-19 |
T45949 | 0-18 | CHEBI:16412;CHEBI:16412 | denotes | Lipopolysaccharide |
T26573 | 33-37 | UBERON:0002048 | denotes | lung |
T67408 | 45-50 | NCBITaxon:10088 | denotes | mouse |
T64221 | 78-88 | GO:0010467 | denotes | expression |
T339 | 92-96 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T57577 | 98-102 | UBERON:0002048 | denotes | lung |
T30771 | 184-195 | GO:0009294 | denotes | transfected |
T2102 | 201-205 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T26427 | 241-245 | UBERON:0002048 | denotes | lung |
T88548 | 259-263 | UBERON:0002048 | denotes | lung |
T40701 | 291-295 | NCBITaxon:10088 | denotes | mice |
T25934 | 305-315 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
T13796 | 341-359 | CHEBI:16412;CHEBI:16412 | denotes | lipopolysaccharide |
T57031 | 368-377 | UBERON:0006562 | denotes | pneumonic |
T56145 | 419-427 | SP_10 | denotes | SARS-CoV |
T3099 | 428-437 | PG_1 | denotes | S protein |
T33336 | 459-463 | UBERON:0002048 | denotes | lung |
T48754 | 480-493 | GO:0065007 | denotes | dysregulation |
T39370 | 515-523 | SP_10 | denotes | SARS-CoV |
T41763 | 539-543 | UBERON:0002048 | denotes | lung |
T35901 | 590-593 | PR:000001251 | denotes | AT1 |
T86863 | 680-688 | SP_7 | denotes | COVID-19 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1316 | 92-96 | Gene | denotes | ACE2 | Gene:70008 |
1317 | 201-205 | Gene | denotes | ACE2 | Gene:70008 |
1318 | 301-304 | Gene | denotes | ACE | Gene:11421 |
1319 | 45-50 | Species | denotes | mouse | Tax:10090 |
1320 | 291-295 | Species | denotes | mice | Tax:10090 |
1321 | 419-427 | Species | denotes | SARS-CoV | Tax:694009 |
1322 | 515-523 | Species | denotes | SARS-CoV | Tax:694009 |
1323 | 666-674 | Species | denotes | patients | Tax:9606 |
1324 | 0-18 | Chemical | denotes | Lipopolysaccharide | MESH:D008070 |
1325 | 341-359 | Chemical | denotes | lipopolysaccharide | MESH:D008070 |
1326 | 27-44 | Disease | denotes | acute lung injury | MESH:D055371 |
1327 | 259-270 | Disease | denotes | lung injury | MESH:D055370 |
1328 | 368-384 | Disease | denotes | pneumonic injury | MESH:D011014 |
1329 | 459-471 | Disease | denotes | lung failure | MESH:D012131 |
1330 | 539-551 | Disease | denotes | lung failure | MESH:D012131 |
1331 | 680-688 | Disease | denotes | COVID-19 | MESH:C000657245 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32305401-31805278-55253005 | 386-388 | 31805278 | denotes | 67 |
32305401-31805278-55253006 | 604-606 | 31805278 | denotes | 67 |