PMC:7161517 / 26895-27129 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T150","span":{"begin":27,"end":34},"obj":"Body_part"},{"id":"T151","span":{"begin":42,"end":49},"obj":"Body_part"},{"id":"T152","span":{"begin":159,"end":165},"obj":"Body_part"}],"attributes":[{"id":"A150","pred":"fma_id","subj":"T150","obj":"http://purl.org/sig/ont/fma/fma66836"},{"id":"A151","pred":"fma_id","subj":"T151","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A152","pred":"fma_id","subj":"T152","obj":"http://purl.org/sig/ont/fma/fma82764"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T139","span":{"begin":105,"end":110},"obj":"Disease"}],"attributes":[{"id":"A139","pred":"mondo_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/MONDO_0005070"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T240","span":{"begin":216,"end":218},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T241","span":{"begin":223,"end":225},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T242","span":{"begin":223,"end":225},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T296","span":{"begin":42,"end":49},"obj":"Chemical"},{"id":"T297","span":{"begin":60,"end":64},"obj":"Chemical"},{"id":"T298","span":{"begin":159,"end":165},"obj":"Chemical"},{"id":"T299","span":{"begin":223,"end":225},"obj":"Chemical"}],"attributes":[{"id":"A296","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A297","pred":"chebi_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T67","span":{"begin":111,"end":119},"obj":"http://purl.obolibrary.org/obo/GO_0070265"},{"id":"T68","span":{"begin":111,"end":119},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T69","span":{"begin":111,"end":119},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T70","span":{"begin":111,"end":119},"obj":"http://purl.obolibrary.org/obo/GO_0001906"},{"id":"T71","span":{"begin":200,"end":209},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-sentences","denotations":[{"id":"T166","span":{"begin":0,"end":234},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T41","span":{"begin":105,"end":110},"obj":"Phenotype"}],"attributes":[{"id":"A41","pred":"hp_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T862","span":{"begin":22,"end":34},"obj":"GO:0044164"},{"id":"T863","span":{"begin":40,"end":49},"obj":"PG_1"},{"id":"T864","span":{"begin":60,"end":64},"obj":"CHEBI:37527;CHEBI:37527"},{"id":"T865","span":{"begin":65,"end":74},"obj":"GO:0010498"},{"id":"T866","span":{"begin":75,"end":86},"obj":"GO:0006508"},{"id":"T867","span":{"begin":87,"end":95},"obj":"MOP:0000780"},{"id":"T868","span":{"begin":99,"end":103},"obj":"G_3;PG_10;PR:000003622"},{"id":"T869","span":{"begin":128,"end":131},"obj":"PR:000000134"},{"id":"T870","span":{"begin":136,"end":149},"obj":"GO:0016020;PG_8"},{"id":"T871","span":{"begin":150,"end":167},"obj":"PG_8"},{"id":"T892","span":{"begin":22,"end":34},"obj":"GO:0044164"},{"id":"T893","span":{"begin":40,"end":49},"obj":"PG_1"},{"id":"T894","span":{"begin":60,"end":64},"obj":"CHEBI:37527;CHEBI:37527"},{"id":"T895","span":{"begin":65,"end":74},"obj":"GO:0010498"},{"id":"T896","span":{"begin":75,"end":86},"obj":"GO:0006508"},{"id":"T897","span":{"begin":87,"end":95},"obj":"MOP:0000780"},{"id":"T898","span":{"begin":99,"end":103},"obj":"G_3;PG_10;PR:000003622"},{"id":"T899","span":{"begin":128,"end":131},"obj":"PR:000000134"},{"id":"T900","span":{"begin":136,"end":149},"obj":"GO:0016020;PG_8"},{"id":"T901","span":{"begin":150,"end":167},"obj":"PG_8"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1142","span":{"begin":99,"end":103},"obj":"Gene"},{"id":"1143","span":{"begin":105,"end":134},"obj":"Gene"},{"id":"1144","span":{"begin":136,"end":167},"obj":"Gene"},{"id":"1150","span":{"begin":40,"end":41},"obj":"Gene"}],"attributes":[{"id":"A1142","pred":"tao:has_database_id","subj":"1142","obj":"Gene:59272"},{"id":"A1143","pred":"tao:has_database_id","subj":"1143","obj":"Gene:7124"},{"id":"A1144","pred":"tao:has_database_id","subj":"1144","obj":"Gene:7113"},{"id":"A1150","pred":"tao:has_database_id","subj":"1150","obj":"Gene:43740568"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit."}