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PMC:7161517 / 26779-27422 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T149 107-114 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T150 143-150 Body_part denotes cytosol http://purl.org/sig/ont/fma/fma66836
T151 158-165 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 275-281 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T153 500-510 Body_part denotes calmodulin http://purl.org/sig/ont/fma/fma62343

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T137 0-47 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T138 49-57 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T139 221-226 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T140 453-461 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T240 332-334 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T241 339-341 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T242 339-341 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T243 351-353 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T244 351-353 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T245 361-368 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T246 386-394 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T295 107-114 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T296 158-165 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T297 176-180 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T298 275-281 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T299 339-341 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T300 351-353 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T301 361-368 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T302 511-521 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T67 227-235 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T68 227-235 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T69 227-235 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T70 227-235 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T71 316-325 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T72 433-444 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T73 533-552 http://purl.obolibrary.org/obo/GO_0006509 denotes ectodomain cleavage

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T165 0-115 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the catalytic site of ACE2 via its S protein.
T166 116-350 Sentence denotes To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit.
T167 351-464 Sentence denotes S2 fusion peptide inserts into the membrane, which allows for clatherin-dependent endocytosis of ACE2-SARS-CoV-2.
T168 465-561 Sentence denotes Viral binding stimulates TNF-α and calmodulin inhibitors to promote ectodomain cleavage of ACE2.
T169 562-643 Sentence denotes ADAM 17 = disintegrin and metalloprotease 17; other abbreviations as in Figure 1.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T41 221-226 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T856 7-12 SP_7 denotes acute
T857 13-24 SP_7;GO:0045333;UBERON:0001004 denotes respiratory
T858 25-47 SP_7 denotes syndrome coronavirus 2
T859 49-59 SP_7 denotes SARS-CoV-2
T860 92-96 G_3;PG_10;PR:000003622 denotes ACE2
T861 105-114 PG_1 denotes S protein
T862 138-150 GO:0044164 denotes host cytosol
T863 156-165 PG_1 denotes S protein
T864 176-180 CHEBI:37527;CHEBI:37527 denotes acid
T865 181-190 GO:0010498 denotes dependent
T866 191-202 GO:0006508 denotes proteolytic
T867 203-211 MOP:0000780 denotes cleavage
T868 215-219 G_3;PG_10;PR:000003622 denotes ACE2
T869 244-247 PR:000000134 denotes TNF
T870 252-265 GO:0016020;PG_8 denotes transmembrane
T871 266-283 PG_8 denotes protease serine 2
T872 369-376 SO:0000667 denotes inserts
T873 386-394 GO:0016020 denotes membrane
T874 413-432 GO:0017156 denotes clatherin-dependent
T875 433-444 GO:0006897 denotes endocytosis
T876 448-452 G_3;PG_10;PR:000003622 denotes ACE2
T877 453-463 SP_7 denotes SARS-CoV-2
T878 490-495 PR:000000134 denotes TNF-α
T879 500-510 PR:000004978 denotes calmodulin
T880 511-521 CHEBI:35222;CHEBI:35222 denotes inhibitors
T881 544-552 MOP:0000780 denotes cleavage
T882 556-560 PR:000003622;G_3;PG_10 denotes ACE2
T883 562-569 PR:000001279 denotes ADAM 17
T886 0-12 SP_7 denotes Severe acute
T887 13-24 SP_7;UBERON:0001004;GO:0045333 denotes respiratory
T888 25-47 SP_7 denotes syndrome coronavirus 2
T889 49-59 SP_7 denotes SARS-CoV-2
T890 92-96 G_3;PG_10;PR:000003622 denotes ACE2
T891 105-114 PG_1 denotes S protein
T892 138-150 GO:0044164 denotes host cytosol
T893 156-165 PG_1 denotes S protein
T894 176-180 CHEBI:37527;CHEBI:37527 denotes acid
T895 181-190 GO:0010498 denotes dependent
T896 191-202 GO:0006508 denotes proteolytic
T897 203-211 MOP:0000780 denotes cleavage
T898 215-219 G_3;PG_10;PR:000003622 denotes ACE2
T899 244-247 PR:000000134 denotes TNF
T900 252-265 GO:0016020;PG_8 denotes transmembrane
T901 266-283 PG_8 denotes protease serine 2
T902 369-376 SO:0000667 denotes inserts
T903 386-394 GO:0016020 denotes membrane
T904 413-432 GO:0017156 denotes clatherin-dependent
T905 433-444 GO:0006897 denotes endocytosis
T906 448-452 G_3;PG_10;PR:000003622 denotes ACE2
T907 453-463 SP_7 denotes SARS-CoV-2
T908 490-495 PR:000000134 denotes TNF-α
T909 500-510 PR:000004978 denotes calmodulin
T910 511-521 CHEBI:35222;CHEBI:35222 denotes inhibitors
T911 544-552 MOP:0000780 denotes cleavage
T912 556-560 PR:000003622;G_3;PG_10 denotes ACE2
T913 562-569 PR:000001279 denotes ADAM 17

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1141 92-96 Gene denotes ACE2 Gene:59272
1142 215-219 Gene denotes ACE2 Gene:59272
1143 221-250 Gene denotes tumor necrosis factor (TNF)-α Gene:7124
1144 252-283 Gene denotes transmembrane protease serine 2 Gene:7113
1145 448-452 Gene denotes ACE2 Gene:59272
1146 490-495 Gene denotes TNF-α Gene:7124
1147 500-510 Gene denotes calmodulin Gene:801
1148 556-560 Gene denotes ACE2 Gene:59272
1149 562-569 Gene denotes ADAM 17 Gene:6868
1150 156-157 Gene denotes S Gene:43740568
1151 105-106 Gene denotes S Gene:43740568
1152 0-47 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
1153 49-59 Species denotes SARS-CoV-2 Tax:2697049
1154 453-463 Species denotes SARS-CoV-2 Tax:2697049
1155 413-422 Chemical denotes clatherin