PMC:7160875 / 8715-9936
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7160875","sourcedb":"PMC","sourceid":"7160875","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7160875","text":"Rampp et al have contributed to firmly establishing MEG as one of the diagnostic tools in the presurgical evaluation of drug-resistant epilepsy. The next step for the field is to elevate the technology from “it would be nice to have in my backyard” to “I need this at my center”. What is needed to make this jump are new findings that would make MEG essential in the diagnostic workup for epilepsy surgery. One potential major advancement is for MEG to identify noninvasive biomarkers of the epileptogenic focus with high positive and negative predictive values. Coincidentally, in the very next issue of Brain after Rampp et al is another MEG paper9 reporting to be the first noninvasive study to detect high-frequency oscillations, address the efficacy of high-frequency oscillations over the different neural oscillatory frequencies, localize them and clinically validate them with the postsurgical outcome in patients with medically refractory epilepsy. Further studies that replicate and validate the finding that high-frequency oscillations detected by MEG significantly improve the presurgical assessment and can predict the postsurgical outcome would make MEG an indispensable technology in every epilepsy center.","tracks":[{"project":"TEST0","denotations":[{"id":"32313499-86-91-4311","span":{"begin":649,"end":650},"obj":"[\"31553044\"]"}],"attributes":[{"subj":"32313499-86-91-4311","pred":"source","obj":"TEST0"}]},{"project":"0_colil","denotations":[{"id":"32313499-31553044-4311","span":{"begin":649,"end":650},"obj":"31553044"}],"attributes":[{"subj":"32313499-31553044-4311","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"32313499-31553044-28641140","span":{"begin":649,"end":650},"obj":"31553044"}],"attributes":[{"subj":"32313499-31553044-28641140","pred":"source","obj":"2_test"}]},{"project":"MyTest","denotations":[{"id":"32313499-31553044-28641140","span":{"begin":649,"end":651},"obj":"31553044"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"32313499-31553044-28641140","pred":"source","obj":"MyTest"}]},{"project":"testtesttest","denotations":[{"id":"T25","span":{"begin":167,"end":172},"obj":"Body_part"},{"id":"T26","span":{"begin":605,"end":610},"obj":"Body_part"}],"attributes":[{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0007688"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"A27","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_6110636"},{"subj":"T25","pred":"source","obj":"testtesttest"},{"subj":"T26","pred":"source","obj":"testtesttest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#93baec","default":true},{"id":"0_colil","color":"#d4ec93"},{"id":"2_test","color":"#ea93ec"},{"id":"MyTest","color":"#93ecd0"},{"id":"testtesttest","color":"#ecb693"}]}]}}