PMC:7160614 / 8632-10028 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"161","span":{"begin":1099,"end":1104},"obj":"Disease"},{"id":"167","span":{"begin":454,"end":462},"obj":"Disease"},{"id":"168","span":{"begin":576,"end":585},"obj":"Disease"},{"id":"169","span":{"begin":594,"end":603},"obj":"Disease"},{"id":"170","span":{"begin":612,"end":621},"obj":"Disease"},{"id":"171","span":{"begin":641,"end":650},"obj":"Disease"}],"attributes":[{"id":"A161","pred":"tao:has_database_id","subj":"161","obj":"MESH:D005334"},{"id":"A167","pred":"tao:has_database_id","subj":"167","obj":"MESH:C000657245"},{"id":"A168","pred":"tao:has_database_id","subj":"168","obj":"MESH:D007239"},{"id":"A169","pred":"tao:has_database_id","subj":"169","obj":"MESH:D007239"},{"id":"A170","pred":"tao:has_database_id","subj":"170","obj":"MESH:D007239"},{"id":"A171","pred":"tao:has_database_id","subj":"171","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T16","span":{"begin":324,"end":328},"obj":"Body_part"},{"id":"T17","span":{"begin":400,"end":404},"obj":"Body_part"},{"id":"T18","span":{"begin":483,"end":487},"obj":"Body_part"},{"id":"T19","span":{"begin":1215,"end":1231},"obj":"Body_part"},{"id":"T20","span":{"begin":1315,"end":1331},"obj":"Body_part"},{"id":"T21","span":{"begin":1367,"end":1382},"obj":"Body_part"}],"attributes":[{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma7333"},{"id":"A20","pred":"fma_id","subj":"T20","obj":"http://purl.org/sig/ont/fma/fma7333"},{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma27360"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T7","span":{"begin":324,"end":328},"obj":"Body_part"},{"id":"T8","span":{"begin":400,"end":404},"obj":"Body_part"},{"id":"T9","span":{"begin":483,"end":487},"obj":"Body_part"},{"id":"T10","span":{"begin":488,"end":492},"obj":"Body_part"},{"id":"T11","span":{"begin":523,"end":527},"obj":"Body_part"},{"id":"T12","span":{"begin":1227,"end":1231},"obj":"Body_part"},{"id":"T13","span":{"begin":1327,"end":1331},"obj":"Body_part"},{"id":"T14","span":{"begin":1367,"end":1382},"obj":"Body_part"},{"id":"T15","span":{"begin":1367,"end":1371},"obj":"Body_part"},{"id":"T16","span":{"begin":1372,"end":1382},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A10","pred":"uberon_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0008946"},{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0000353"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T48","span":{"begin":454,"end":462},"obj":"Disease"},{"id":"T49","span":{"begin":576,"end":585},"obj":"Disease"},{"id":"T50","span":{"begin":594,"end":603},"obj":"Disease"},{"id":"T51","span":{"begin":612,"end":621},"obj":"Disease"},{"id":"T52","span":{"begin":641,"end":650},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T50","span":{"begin":132,"end":133},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T51","span":{"begin":324,"end":328},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T52","span":{"begin":324,"end":328},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T53","span":{"begin":400,"end":404},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T54","span":{"begin":400,"end":404},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T55","span":{"begin":430,"end":432},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T56","span":{"begin":483,"end":487},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T57","span":{"begin":483,"end":487},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T58","span":{"begin":721,"end":722},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T59","span":{"begin":757,"end":758},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T60","span":{"begin":768,"end":770},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"},{"id":"T61","span":{"begin":962,"end":964},"obj":"http://purl.obolibrary.org/obo/CLO_0002860"},{"id":"T62","span":{"begin":1031,"end":1032},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T63","span":{"begin":1045,"end":1051},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T64","span":{"begin":1057,"end":1058},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T65","span":{"begin":1139,"end":1140},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T66","span":{"begin":1367,"end":1371},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T67","span":{"begin":1367,"end":1371},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T14","span":{"begin":1099,"end":1104},"obj":"Phenotype"}],"attributes":[{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0001945"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}

{"project":"LitCovid-sentences","denotations":[{"id":"T69","span":{"begin":0,"end":189},"obj":"Sentence"},{"id":"T70","span":{"begin":190,"end":285},"obj":"Sentence"},{"id":"T71","span":{"begin":286,"end":434},"obj":"Sentence"},{"id":"T72","span":{"begin":435,"end":665},"obj":"Sentence"},{"id":"T73","span":{"begin":666,"end":756},"obj":"Sentence"},{"id":"T74","span":{"begin":757,"end":862},"obj":"Sentence"},{"id":"T75","span":{"begin":863,"end":966},"obj":"Sentence"},{"id":"T76","span":{"begin":967,"end":1023},"obj":"Sentence"},{"id":"T77","span":{"begin":1024,"end":1105},"obj":"Sentence"},{"id":"T78","span":{"begin":1106,"end":1232},"obj":"Sentence"},{"id":"T79","span":{"begin":1233,"end":1268},"obj":"Sentence"},{"id":"T80","span":{"begin":1269,"end":1310},"obj":"Sentence"},{"id":"T81","span":{"begin":1311,"end":1396},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"For extraction of radiological semantic features, two senior radiologists (D.L. and X.C., more than 15 years of experience) reached a consensus, blinded to clinical and laboratory findings. The radiological semantic features included both qualitative and quantitative imaging features. The lesions in the outer third of the lung were defined as peripheral, and lesions in the inner two-thirds of the lung were defined as central [22]. The progression of COVID-19 lesions within each lung lobe was evaluated by scoring each lobe from 0 to 4 [7], corresponding to normal, 1~25% infection, 26~50% infection, 51~75% infection, and more than 75% infection, respectively. The scores were combined for all five lobes to provide a total score ranging from 0 to 20. A total of 41 radiological features (26 quantitative and 15 qualitative) were extracted for the analysis. The descriptions of radiological semantic features are listed in the Supplementary Material (Table E2). Figure 1 is one example of the evaluation of CT imaging.\nFig. 1 A 23-year-old female with a travel history to Wuhan presenting with fever. Axial noncontrast CT image shows a consolidation with ground-glass opacities in the peripheral region by the right upper lobe. Air bronchogram is found in lesion. The maximum diameter of lesion is 2.8 cm. The right upper lobe score is 1 because of the involved lung parenchyma less than 1/4"}