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PMC:7160614 / 144-2589 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
10 203-211 Species denotes patients Tax:9606
11 43-67 Disease denotes coronavirus disease 2019 MESH:C000657245
12 69-77 Disease denotes COVID-19 MESH:C000657245
13 193-202 Disease denotes pneumonia MESH:D011014
14 229-237 Disease denotes COVID-19 MESH:C000657245
15 290-298 Disease denotes COVID-19 MESH:C000657245
20 434-442 Species denotes patients Tax:9606
21 498-506 Species denotes Patients Tax:9606
22 395-403 Disease denotes COVID-19 MESH:C000657245
23 415-433 Disease denotes COVID-19 pneumonia MESH:C000657245
25 1298-1306 Disease denotes COVID-19 MESH:C000657245
30 1686-1694 Species denotes patients Tax:9606
31 1676-1685 Disease denotes pneumonia MESH:D011014
32 1712-1720 Disease denotes COVID-19 MESH:C000657245
33 1857-1865 Disease denotes COVID-19 MESH:C000657245
37 1950-1958 Species denotes patients Tax:9606
38 1940-1949 Disease denotes pneumonia MESH:D011014
39 1976-1984 Disease denotes COVID-19 MESH:C000657245
41 2032-2040 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 1216-1220 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T2 1320-1324 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1216-1220 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 1320-1324 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T3 43-67 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T4 69-77 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 193-202 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T6 229-237 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 290-298 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 395-403 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 415-423 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 424-433 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T11 1298-1306 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T12 1676-1685 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T13 1712-1720 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 1857-1865 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 1940-1949 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T16 1976-1984 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 2032-2040 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T3 0-10 http://purl.obolibrary.org/obo/BFO_0000030 denotes Objectives
T4 115-118 http://purl.obolibrary.org/obo/PR_000001343 denotes aim
T5 267-268 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 368-369 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T7 590-594 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T8 608-612 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T9 635-639 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T10 1216-1220 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T11 1216-1220 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T12 1320-1324 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T13 1320-1324 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T14 1536-1537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 1743-1744 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T16 1807-1810 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T17 2009-2010 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 193-202 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 424-433 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 1676-1685 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 1940-1949 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-10 Sentence denotes Objectives
T4 11-111 Sentence denotes Rapid and accurate diagnosis of coronavirus disease 2019 (COVID-19) is critical during the epidemic.
T5 112-358 Sentence denotes We aim to identify differences in CT imaging and clinical manifestations between pneumonia patients with and without COVID-19, and to develop and validate a diagnostic model for COVID-19 based on radiological semantic and clinical features alone.
T6 360-367 Sentence denotes Methods
T7 368-497 Sentence denotes A consecutive cohort of 70 COVID-19 and 66 non-COVID-19 pneumonia patients were retrospectively recruited from five institutions.
T8 498-574 Sentence denotes Patients were divided into primary (n = 98) and validation (n = 38) cohorts.
T9 575-713 Sentence denotes The chi-square test, Student’s t test, and Kruskal-Wallis H test were performed, comparing 1745 lesions and 67 features in the two groups.
T10 714-835 Sentence denotes Three models were constructed using radiological semantic and clinical features through multivariate logistic regression.
T11 836-937 Sentence denotes Diagnostic efficacies of developed models were quantified by receiver operating characteristic curve.
T12 938-1007 Sentence denotes Clinical usage was evaluated by decision curve analysis and nomogram.
T13 1009-1016 Sentence denotes Results
T14 1017-1135 Sentence denotes Eighteen radiological semantic features and seventeen clinical features were identified to be significantly different.
T15 1136-1319 Sentence denotes Besides ground-glass opacities (p = 0.032) and consolidation (p = 0.001) in the lung periphery, the lesion size (1–3 cm) is also significant for the diagnosis of COVID-19 (p = 0.027).
T16 1320-1378 Sentence denotes Lung score presents no significant difference (p = 0.417).
T17 1379-1480 Sentence denotes Three diagnostic models achieved an area under the curve value as high as 0.986 (95% CI 0.966~1.000).
T18 1481-1603 Sentence denotes The clinical and radiological semantic models provided a better diagnostic performance and more considerable net benefits.
T19 1605-1616 Sentence denotes Conclusions
T20 1617-1742 Sentence denotes Based on CT imaging and clinical manifestations alone, the pneumonia patients with and without COVID-19 can be distinguished.
T21 1743-1866 Sentence denotes A model composed of radiological semantic and clinical features has an excellent performance for the diagnosis of COVID-19.
T22 1868-1878 Sentence denotes Key Points
T23 1879-2006 Sentence denotes • Based on CT imaging and clinical manifestations alone, the pneumonia patients with and without COVID-19 can be distinguished.
T24 2007-2273 Sentence denotes • A diagnostic model for COVID-19 was developed and validated using radiological semantic and clinical features, which had an area under the curve value of 0.986 (95% CI 0.966~1.000) and 0.936 (95% CI 0.866~1.000) in the primary and validation cohorts, respectively.
T25 2275-2308 Sentence denotes Electronic supplementary material
T26 2309-2445 Sentence denotes The online version of this article (10.1007/s00330-020-06829-2) contains supplementary material, which is available to authorized users.