PMC:7160442 / 4486-5477
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7160442","sourcedb":"PMC","sourceid":"7160442","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7160442","text":"The virus causing COVID-19 was identified and announced on 7 January and by 10 January, sequences of five genomes had been shared, providing scientists around the world with a basis for development of diagnostic tests [8]. There was fast growing knowledge about several important parameters for understanding the spread of disease. A number of studies in various settings determined the basic reproductive number R0 to be within the range of 2–3 [9,10]; the incubation period was determined as ranging from 1 to 14 days with an average of 5–6 days; transmission through droplets was established as the main mode of transmission; the clinical picture that emerged included a wide range from mild symptoms with fever, sore throat and cough to severe pneumonias with characteristic features on computed tomography scans; in Hubei, China, up to 13.8% of laboratory-confirmed patients had severe disease, 6.1% were critically ill and the case fatality rate among all COVID-19 cases was 2.3% 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