PMC:7156291 / 8168-11037
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
155 | 0-7 | Species | denotes | Patient | Tax:9606 |
161 | 27-35 | Species | denotes | patients | Tax:9606 |
162 | 171-179 | Species | denotes | patients | Tax:9606 |
163 | 359-367 | Species | denotes | patients | Tax:9606 |
164 | 453-461 | Species | denotes | patients | Tax:9606 |
165 | 471-480 | Disease | denotes | pneumonia | MESH:D011014 |
181 | 2047-2050 | Gene | denotes | AST | Gene:26503 |
182 | 2148-2166 | Gene | denotes | C-reactive protein | Gene:1401 |
183 | 997-1004 | Species | denotes | Patient | Tax:9606 |
184 | 1229-1236 | Species | denotes | patient | Tax:9606 |
185 | 1010-1013 | Disease | denotes | NCP | MESH:C000657245 |
186 | 1220-1228 | Disease | denotes | infected | MESH:D007239 |
187 | 1284-1300 | Disease | denotes | symptoms Fever | MESH:D051271 |
188 | 1313-1318 | Disease | denotes | Cough | MESH:D003371 |
189 | 1357-1364 | Disease | denotes | Fatigue | MESH:D005221 |
190 | 1399-1418 | Disease | denotes | shortness of breath | MESH:D004417 |
191 | 1431-1443 | Disease | denotes | Pharyngalgia | MESH:D010608 |
192 | 1482-1490 | Disease | denotes | Headache | MESH:D006261 |
193 | 1501-1507 | Disease | denotes | Nausea | MESH:D009325 |
194 | 1515-1523 | Disease | denotes | vomiting | MESH:D014839 |
195 | 1532-1540 | Disease | denotes | Diarrhea | MESH:D003967 |
197 | 933-940 | Species | denotes | Patient | Tax:9606 |
199 | 2268-2276 | Species | denotes | patients | Tax:9606 |
201 | 2340-2343 | Gene | denotes | AST | Gene:26503 |
203 | 2371-2376 | Chemical | denotes | aData | |
206 | 2671-2674 | Gene | denotes | AST | Gene:26503 |
207 | 2709-2727 | Gene | denotes | C-reactive protein | Gene:1401 |
216 | 871-889 | Gene | denotes | C-reactive protein | Gene:1401 |
217 | 577-585 | Species | denotes | Patients | Tax:9606 |
218 | 657-664 | Species | denotes | patient | Tax:9606 |
219 | 850-858 | Species | denotes | patients | Tax:9606 |
220 | 915-923 | Species | denotes | patients | Tax:9606 |
221 | 648-656 | Disease | denotes | infected | MESH:D007239 |
222 | 703-708 | Disease | denotes | Fever | MESH:D005334 |
223 | 721-726 | Disease | denotes | cough | MESH:D003371 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T11 | 781-791 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T12 | 802-806 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T13 | 882-889 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T14 | 1377-1382 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T15 | 1456-1462 | Body_part | denotes | Muscle | http://purl.org/sig/ont/fma/fma32558 |
T16 | 1625-1641 | Body_part | denotes | White blood cell | http://purl.org/sig/ont/fma/fma62852 |
T17 | 1637-1641 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T18 | 1690-1700 | Body_part | denotes | Lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T19 | 1757-1768 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T20 | 1819-1831 | Body_part | denotes | neutrophilic | http://purl.org/sig/ont/fma/fma62860 |
T21 | 1832-1843 | Body_part | denotes | granulocyte | http://purl.org/sig/ont/fma/fma62854 |
T22 | 1896-1905 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
T23 | 1948-1958 | Body_part | denotes | Hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T24 | 2159-2166 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T25 | 2314-2321 | Body_part | denotes | alanine | http://purl.org/sig/ont/fma/fma82749 |
T26 | 2550-2566 | Body_part | denotes | white blood cell | http://purl.org/sig/ont/fma/fma62852 |
T27 | 2562-2566 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T28 | 2574-2584 | Body_part | denotes | lymphocyte | http://purl.org/sig/ont/fma/fma62863 |
T29 | 2600-2611 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T30 | 2621-2633 | Body_part | denotes | neutrophilic | http://purl.org/sig/ont/fma/fma62860 |
T31 | 2634-2645 | Body_part | denotes | granulocyte | http://purl.org/sig/ont/fma/fma62854 |
T32 | 2655-2664 | Body_part | denotes | monocytes | http://purl.org/sig/ont/fma/fma62864 |
T33 | 2693-2703 | Body_part | denotes | hemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T34 | 2720-2727 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T17 | 1377-1382 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T18 | 1631-1636 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
T19 | 2556-2561 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T34 | 471-480 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T35 | 1532-1540 | Disease | denotes | Diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T38 | 73-77 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
T39 | 73-77 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
T40 | 98-104 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | female |
T41 | 217-219 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T42 | 802-806 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T43 | 969-973 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T44 | 1034-1035 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T45 | 1089-1091 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
T46 | 1101-1103 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T47 | 1134-1138 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | Male |
T48 | 1134-1138 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | Male |
T49 | 1195-1197 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T50 | 1377-1382 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T51 | 1456-1462 | http://purl.obolibrary.org/obo/UBERON_0001630 | denotes | Muscle |
T52 | 1456-1462 | http://purl.obolibrary.org/obo/UBERON_0005090 | denotes | Muscle |
T53 | 1456-1462 | http://www.ebi.ac.uk/efo/EFO_0000801 | denotes | Muscle |
T54 | 1456-1462 | http://www.ebi.ac.uk/efo/EFO_0001949 | denotes | Muscle |
T55 | 1588-1595 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | testing |
T56 | 1631-1636 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
T57 | 1637-1641 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T58 | 1678-1680 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T59 | 1896-1905 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
T60 | 2177-2179 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
T61 | 2556-2561 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
T62 | 2562-2566 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T63 | 2655-2664 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocytes |
T64 | 2822-2824 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T12 | 73-77 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
T13 | 882-889 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T14 | 1052-1057 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
T15 | 1948-1958 | Chemical | denotes | Hemoglobin | http://purl.obolibrary.org/obo/CHEBI_5656 |
T16 | 2047-2050 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
T17 | 2091-2099 | Chemical | denotes | Creatine | http://purl.obolibrary.org/obo/CHEBI_16919 |
T18 | 2159-2166 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T19 | 2314-2321 | Chemical | denotes | alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
T20 | 2340-2343 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
T21 | 2344-2353 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
T24 | 2671-2674 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
T25 | 2676-2684 | Chemical | denotes | creatine | http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947 |
T27 | 2693-2703 | Chemical | denotes | hemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T28 | 2720-2727 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T24 | 471-480 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T25 | 703-708 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
T26 | 721-726 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
T27 | 1295-1300 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
T28 | 1313-1318 | Phenotype | denotes | Cough | http://purl.obolibrary.org/obo/HP_0012735 |
T29 | 1357-1364 | Phenotype | denotes | Fatigue | http://purl.obolibrary.org/obo/HP_0012378 |
T30 | 1399-1418 | Phenotype | denotes | shortness of breath | http://purl.obolibrary.org/obo/HP_0002098 |
T31 | 1431-1443 | Phenotype | denotes | Pharyngalgia | http://purl.obolibrary.org/obo/HP_0033050 |
T32 | 1482-1490 | Phenotype | denotes | Headache | http://purl.obolibrary.org/obo/HP_0002315 |
T33 | 1501-1523 | Phenotype | denotes | Nausea and/or vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T34 | 1532-1540 | Phenotype | denotes | Diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T73 | 0-20 | Sentence | denotes | Patient demographics |
T74 | 21-150 | Sentence | denotes | Of 88 patients in the study cohort, 51 (58.0%) were male and 37 (42.0%) were female; mean age was 42.7 years (range, 4–82 years). |
T75 | 151-246 | Sentence | denotes | Fifty-three (60.2%) patients had 2 CTs, 24 (27.2%) had 3 CTs, and 11 (12.5%) had 4 or more CTs. |
T76 | 247-346 | Sentence | denotes | The mean time interval between symptom onset and baseline CT was 5.5 ± 3.5 days (range, 1–15 days). |
T77 | 347-441 | Sentence | denotes | Five (5.7%) patients in the study cohort were known to have been discharged from the hospital. |
T78 | 442-514 | Sentence | denotes | All of the patients had mild pneumonia based on the WHO definition [10]. |
T79 | 515-576 | Sentence | denotes | The demographics of the study cohort are detailed in Table 1. |
T80 | 577-702 | Sentence | denotes | Patients with exposure history (recent travel to Wuhan or contact with infected patient) accounted for 85.2% of study cohort. |
T81 | 703-776 | Sentence | denotes | Fever (84.1%) and cough (56.8%) were the most common presenting symptoms. |
T82 | 777-924 | Sentence | denotes | Low lymphocyte and white cell counts were observed in 26.4% and 25.0% of patients, while high C-reactive protein was observed in 55.0% of patients. |
T83 | 925-981 | Sentence | denotes | Table 1 Patient demographics and laboratory test results |
T84 | 982-1022 | Sentence | denotes | Characteristic Patient with NCP (n = 88) |
T85 | 1023-1047 | Sentence | denotes | Age (years)a 42.7 ± 14.5 |
T86 | 1048-1065 | Sentence | denotes | Age group (years) |
T87 | 1066-1080 | Sentence | denotes | < 15 2 (2.3) |
T88 | 1081-1098 | Sentence | denotes | 15–44 48 (54.5) |
T89 | 1099-1116 | Sentence | denotes | 45–64 28 (31.8) |
T90 | 1117-1133 | Sentence | denotes | ≥ 65 10 (11.4) |
T91 | 1134-1152 | Sentence | denotes | Male sex 51 (58.0) |
T92 | 1153-1169 | Sentence | denotes | Exposure history |
T93 | 1170-1204 | Sentence | denotes | Recent travel to Wuhan 45 (51.1) |
T94 | 1205-1246 | Sentence | denotes | Contact with infected patient 30 (34.1) |
T95 | 1247-1275 | Sentence | denotes | Unknown exposure 13 (14.8) |
T96 | 1276-1292 | Sentence | denotes | Initial symptoms |
T97 | 1293-1310 | Sentence | denotes | Fever 74 (84.1) |
T98 | 1311-1328 | Sentence | denotes | Cough 50 (56.8) |
T99 | 1329-1354 | Sentence | denotes | Expectoration 19 (21.6) |
T100 | 1355-1374 | Sentence | denotes | Fatigue 15 (17.0) |
T101 | 1375-1428 | Sentence | denotes | Chest distress and/or shortness of breath 12 (13.6) |
T102 | 1429-1453 | Sentence | denotes | Pharyngalgia 10 (11.4) |
T103 | 1454-1479 | Sentence | denotes | Muscle soreness 7 (8.0) |
T104 | 1480-1498 | Sentence | denotes | Headache 5 (5.7) |
T105 | 1499-1529 | Sentence | denotes | Nausea and/or vomiting 0 (0) |
T106 | 1530-1546 | Sentence | denotes | Diarrhea 0 (0) |
T107 | 1547-1576 | Sentence | denotes | No obvious symptoms 3 (3.4) |
T108 | 1577-1622 | Sentence | denotes | Laboratory testing at initial hospital visitb |
T109 | 1623-1687 | Sentence | denotes | White blood cell count (–, ↑, ↓) 62 (70.5), 4 (4.5), 22 (25.0) |
T110 | 1688-1746 | Sentence | denotes | Lymphocyte count (–, ↑, ↓) 62 (71.3), 2 (2.3), 23 (26.4) |
T111 | 1747-1808 | Sentence | denotes | Percent lymphocytes (–, ↑, ↓) 55 (62.5), 7 (8.0), 26 (29.5) |
T112 | 1809-1885 | Sentence | denotes | Percent neutrophilic granulocyte (–, ↑, ↓) 59 (67.1), 17 (19.3), 12 (13.6) |
T113 | 1886-1945 | Sentence | denotes | Percent monocytes (–, ↑, ↓) 59 (67.1), 26 (29.5), 3 (3.4) |
T114 | 1946-1998 | Sentence | denotes | Hemoglobin (–, ↑, ↓) 68 (77.3), 8 (9.1), 12 (13.6) |
T115 | 1999-2044 | Sentence | denotes | ALT (–, ↑, ↓) 70 (79.5), 16 (18.2), 2 (2.3) |
T116 | 2045-2088 | Sentence | denotes | AST (–, ↑, ↓) 73 (83.0), 15 (17.0), 0 (0) |
T117 | 2089-2145 | Sentence | denotes | Creatine kinase (–, ↑, ↓) 73 (84.9), 4 (4.6), 9 (10.5) |
T118 | 2146-2204 | Sentence | denotes | C-reactive protein (–, ↑, ↓) 36 (45.0), 44 (55.0), 0 (0) |
T119 | 2205-2309 | Sentence | denotes | Unless otherwise indicated, data are reported as the number of patients, with percentages in parentheses |
T120 | 2310-2370 | Sentence | denotes | ALT alanine aminotransferase, AST aspartate aminotransferase |
T121 | 2371-2423 | Sentence | denotes | aData are reported as the mean ± standard derivation |
T122 | 2424-2532 | Sentence | denotes | bThe signs –, ↑, and ↓ represent within, above, and below normal ranges of laboratory results, respectively. |
T123 | 2533-2869 | Sentence | denotes | Normal ranges of white blood cell count, lymphocyte count, percent lymphocytes, percent neutrophilic granulocyte, percent monocytes, ALT, AST, creatine kinase, hemoglobin, and C-reactive protein were 3.5–9.5 × 109/L, 1.10–3.20 × 109/L, 20–50%, 3.0–10.0%, 40–75%, 115–150 g/L, 7–40 U/L, 13–35 U/L, 40–200 U/L, and 0–10 mg/L, respectively |